-
1
-
-
0036096897
-
Oxysterols: Friends, foes, or just fellow passengers?
-
Björkhem, I.; Diczfalusy, U. Oxysterols: Friends, foes, or just fellow passengers? Arterioscler. Thromb. Vasc. Biol. 2002, 22, 734-742.
-
(2002)
Arterioscler. Thromb. Vasc. Biol
, vol.22
, pp. 734-742
-
-
Björkhem, I.1
Diczfalusy, U.2
-
2
-
-
84900108597
-
Oxysterols and oxysterol-binding proteins in cellular lipid metabolism
-
In, Ehnholm, C., Ed.; Springer: Heidelberg, Germany
-
Olkkonen, V.M. Oxysterols and oxysterol-binding proteins in cellular lipid metabolism. In Cellular Lipid Metabolism; Ehnholm, C., Ed.; Springer: Heidelberg, Germany, 2009, pp. 27-71.
-
(2009)
Cellular Lipid Metabolism
, pp. 27-71
-
-
Olkkonen, V.M.1
-
3
-
-
0342316532
-
Oxysterols: Modulators of cholesterol metabolism and other processes
-
Schroepfer, G.J., Jr. Oxysterols: Modulators of cholesterol metabolism and other processes. Physiol. Rev. 2000, 80, 361-554.
-
(2000)
Physiol. Rev
, vol.80
, pp. 361-554
-
-
Schroepfer Jr., G.J.1
-
4
-
-
0034672672
-
Oxysterol biosynthetic enzymes
-
Russell, D.W. Oxysterol biosynthetic enzymes. Biochim. Biophys. Acta 2000, 1529, 126-135.
-
(2000)
Biochim. Biophys. Acta
, vol.1529
, pp. 126-135
-
-
Russell, D.W.1
-
5
-
-
34547887264
-
Cytochrome P450-Physiological key factor against cholesterol accumulation and the atherosclerotic vascular process
-
Luoma, P.V. Cytochrome P450-Physiological key factor against cholesterol accumulation and the atherosclerotic vascular process. Ann. Med. 2007, 39, 359-370.
-
(2007)
Ann. Med
, vol.39
, pp. 359-370
-
-
Luoma, P.V.1
-
6
-
-
33947706821
-
Rediscovery of cerebrosterol
-
Björkhem, I. Rediscovery of cerebrosterol. Lipids 2007, 42, 5-14.
-
(2007)
Lipids
, vol.42
, pp. 5-14
-
-
Björkhem, I.1
-
7
-
-
0035076216
-
Genes involved in initial steps of bile acid synthesis
-
Björkhem, I.; Eggertsen, G. Genes involved in initial steps of bile acid synthesis. Curr. Opin. Lipidol. 2001, 12, 97-103.
-
(2001)
Curr. Opin. Lipidol
, vol.12
, pp. 97-103
-
-
Björkhem, I.1
Eggertsen, G.2
-
8
-
-
0030720329
-
Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport
-
Babiker, A.; Andersson, O.; Lund, E.; Xiu, R.J.; Deeb, S.; Reshef, A.; Leitersdorf, E.; Diczfalusy, U.; Björkhem, I. Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport. J. Biol. Chem. 1997, 272, 26253-26261.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 26253-26261
-
-
Babiker, A.1
Andersson, O.2
Lund, E.3
Xiu, R.J.4
Deeb, S.5
Reshef, A.6
Leitersdorf, E.7
Diczfalusy, U.8
Björkhem, I.9
-
9
-
-
0037200017
-
Metabolism of 4 beta-hydroxycholesterol in humans
-
Bodin, K.; Andersson, U.; Rystedt, E.; Ellis, E.; Norlin, M.; Pikuleva, I.; Eggertsen, G.; Björkhem, I.; Diczfalusy, U. Metabolism of 4 beta-hydroxycholesterol in humans. J. Biol. Chem. 2002, 277, 31534-31540.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 31534-31540
-
-
Bodin, K.1
Andersson, U.2
Rystedt, E.3
Ellis, E.4
Norlin, M.5
Pikuleva, I.6
Eggertsen, G.7
Björkhem, I.8
Diczfalusy, U.9
-
10
-
-
0032890337
-
Oxysterols and atherosclerosis
-
Brown, A.J.; Jessup, W. Oxysterols and atherosclerosis. Atherosclerosis 1999, 142, 1-28.
-
(1999)
Atherosclerosis
, vol.142
, pp. 1-28
-
-
Brown, A.J.1
Jessup, W.2
-
11
-
-
63249096864
-
Oxysterols and mechanisms of apoptotic signaling: Implications in the pathology of degenerative diseases
-
Lordan, S.; Mackrill, J.J.; O'Brien, N.M. Oxysterols and mechanisms of apoptotic signaling: Implications in the pathology of degenerative diseases. J. Nutr. Biochem. 2009, 20, 321-336.
-
(2009)
J. Nutr. Biochem
, vol.20
, pp. 321-336
-
-
Lordan, S.1
Mackrill, J.J.2
O'Brien, N.M.3
-
12
-
-
11144233997
-
Oxysterols and oxysterol binding proteins: Role in lipid metabolism and atherosclerosis
-
Olkkonen, V.M.; Lehto, M. Oxysterols and oxysterol binding proteins: Role in lipid metabolism and atherosclerosis. Ann. Med. 2004, 36, 562-572.
-
(2004)
Ann. Med
, vol.36
, pp. 562-572
-
-
Olkkonen, V.M.1
Lehto, M.2
-
13
-
-
77958057683
-
Macrophages, oxysterols and atherosclerosis
-
Shibata, N.; Glass, C.K. Macrophages, oxysterols and atherosclerosis. Circ. J. 2010, 74, 2045-2051.
-
(2010)
Circ. J
, vol.74
, pp. 2045-2051
-
-
Shibata, N.1
Glass, C.K.2
-
14
-
-
84860317712
-
Contribution of cholesterol and oxysterols in the physiopathology of cataract: Implication for the development of pharmacological treatments
-
doi:10.1155/2011/471947
-
Vejux, A.; Samadi, M.; Lizard, G. Contribution of cholesterol and oxysterols in the physiopathology of cataract: Implication for the development of pharmacological treatments. J. Ophthalmol. 2011, 2011, doi:10.1155/2011/471947.
-
(2011)
J. Ophthalmol
, vol.2011
-
-
Vejux, A.1
Samadi, M.2
Lizard, G.3
-
15
-
-
0034961072
-
Good cholesterol, bad cholesterol: Role of oxysterols in biliary tract diseases
-
Wang, D.Q.; Afdhal, N.H. Good cholesterol, bad cholesterol: Role of oxysterols in biliary tract diseases. Gastroenterology 2001, 121, 216-218.
-
(2001)
Gastroenterology
, vol.121
, pp. 216-218
-
-
Wang, D.Q.1
Afdhal, N.H.2
-
16
-
-
65549154386
-
The retinal oxysterol pathway: A unifying hypothesis for the cause of age-related macular degeneration
-
Javitt, N.B.; Javitt, J.C. The retinal oxysterol pathway: A unifying hypothesis for the cause of age-related macular degeneration. Curr. Opin. Ophthalmol. 2009, 20, 151-157.
-
(2009)
Curr. Opin. Ophthalmol
, vol.20
, pp. 151-157
-
-
Javitt, N.B.1
Javitt, J.C.2
-
17
-
-
79954986242
-
Oxysterol derivatives of cholesterol in neurodegenerative disorders
-
Jeitner, T.M.; Voloshyna, I.; Reiss, A.B. Oxysterol derivatives of cholesterol in neurodegenerative disorders. Curr. Med. Chem. 2011, 18, 1515-1525.
-
(2011)
Curr. Med. Chem
, vol.18
, pp. 1515-1525
-
-
Jeitner, T.M.1
Voloshyna, I.2
Reiss, A.B.3
-
18
-
-
53149118574
-
Sterol regulators of cholesterol homeostasis and beyond: The oxysterol hypothesis revisited and revised
-
Gill, S.; Chow, R.; Brown, A.J. Sterol regulators of cholesterol homeostasis and beyond: The oxysterol hypothesis revisited and revised. Prog. Lipid Res. 2008, 47, 391-404.
-
(2008)
Prog. Lipid Res
, vol.47
, pp. 391-404
-
-
Gill, S.1
Chow, R.2
Brown, A.J.3
-
19
-
-
0029805887
-
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
-
Janowski, B.A.; Willy, P.J.; Devi, T.R.; Falck, J.R.; Mangelsdorf, D.J. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 1996, 383, 728-731.
-
(1996)
Nature
, vol.383
, pp. 728-731
-
-
Janowski, B.A.1
Willy, P.J.2
Devi, T.R.3
Falck, J.R.4
Mangelsdorf, D.J.5
-
20
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
Lehmann, J.M.; Kliewer, S.A.; Moore, L.B.; Smith-Oliver, T.A.; Oliver, B.B.; Su, J.L.; Sundseth, S.S.; Winegar, D.A.; Blanchard, D.E.; Spencer, T.A.; Willson, T.M. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J. Biol. Chem. 1997, 272, 3137-3140.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Willson, T.M.11
-
21
-
-
0035914330
-
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
-
Fu, X.; Menke, J.G.; Chen, Y.; Zhou, G.; MacNaul, K.L.; Wright, S.D.; Sparrow, C.P.; Lund, E.G. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J. Biol. Chem. 2001, 276, 38378-38387.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 38378-38387
-
-
Fu, X.1
Menke, J.G.2
Chen, Y.3
Zhou, G.4
McNaul, K.L.5
Wright, S.D.6
Sparrow, C.P.7
Lund, E.G.8
-
22
-
-
0037503924
-
Liver X receptor signaling pathways in cardiovascular disease
-
Tontonoz, P.; Mangelsdorf, D.J. Liver X receptor signaling pathways in cardiovascular disease. Mol. Endocrinol. 2003, 17, 985-993.
-
(2003)
Mol. Endocrinol
, vol.17
, pp. 985-993
-
-
Tontonoz, P.1
Mangelsdorf, D.J.2
-
23
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
Joseph, S.B.; Castrillo, A.; Laffitte, B.A.; Mangelsdorf, D.J.; Tontonoz, P. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 2003, 9, 213-219.
-
(2003)
Nat. Med
, vol.9
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
24
-
-
77955129487
-
Liver x receptor signaling pathways and atherosclerosis
-
Calkin, A.C.; Tontonoz, P. Liver x receptor signaling pathways and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2010, 30, 1513-1518.
-
(2010)
Arterioscler. Thromb. Vasc. Biol
, vol.30
, pp. 1513-1518
-
-
Calkin, A.C.1
Tontonoz, P.2
-
25
-
-
0037188553
-
Synthetic LXR ligand inhibits the development of atherosclerosis in mice
-
Joseph, S.B.; McKilligin, E.; Pei, L.; Watson, M.A.; Collins, A.R.; Laffitte, B.A.; Chen, M.; Noh, G.; Goodman, J.; Hagger, G.N.; Tran, J.; Tippin, T.K.; Wang, X.; Lusis, A.J.; Hsueh, W.A.; Law, R.E.; Collins, J.L.; Willson, T.M.; Tontonoz, P. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proc. Natl. Acad. Sci. USA 2002, 99, 7604-7609.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7604-7609
-
-
Joseph, S.B.1
McKilligin, E.2
Pei, L.3
Watson, M.A.4
Collins, A.R.5
Laffitte, B.A.6
Chen, M.7
Noh, G.8
Goodman, J.9
Hagger, G.N.10
Tran, J.11
Tippin, T.K.12
Wang, X.13
Lusis, A.J.14
Hsueh, W.A.15
Law, R.E.16
Collins, J.L.17
Willson, T.M.18
Tontonoz, P.19
-
26
-
-
0037183561
-
Accumulation of foam cells in liver X receptor-deficient mice
-
Schuster, G.U.; Parini, P.; Wang, L.; Alberti, S.; Steffensen, K.R.; Hansson, G.K.; Angelin, B.; Gustafsson, J.A. Accumulation of foam cells in liver X receptor-deficient mice. Circulation 2002, 106, 1147-1153.
-
(2002)
Circulation
, vol.106
, pp. 1147-1153
-
-
Schuster, G.U.1
Parini, P.2
Wang, L.3
Alberti, S.4
Steffensen, K.R.5
Hansson, G.K.6
Angelin, B.7
Gustafsson, J.A.8
-
27
-
-
0034669171
-
Role of LXRs in control of lipogenesis
-
Schultz, J.R.; Tu, H.; Luk, A.; Repa, J.J.; Medina, J.C.; Li, L.; Schwendner, S.; Wang, S.; Thoolen, M.; Mangelsdorf, D.J.; Lustig, K.D.; Shan, B. Role of LXRs in control of lipogenesis. Genes Dev. 2000, 14, 2831-2838.
-
(2000)
Genes Dev
, vol.14
, pp. 2831-2838
-
-
Schultz, J.R.1
Tu, H.2
Luk, A.3
Repa, J.J.4
Medina, J.C.5
Li, L.6
Schwendner, S.7
Wang, S.8
Thoolen, M.9
Mangelsdorf, D.J.10
Lustig, K.D.11
Shan, B.12
-
28
-
-
78651346813
-
Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosis
-
Lo Sasso, G.; Murzilli, S.; Salvatore, L.; D'Errico, I.; Petruzzelli, M.; Conca, P.; Jiang, Z.Y.; Calabresi, L.; Parini, P.; Moschetta, A. Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosis. Cell. Metab. 2010, 12, 187-193.
-
(2010)
Cell. Metab
, vol.12
, pp. 187-193
-
-
Lo Sasso, G.1
Murzilli, S.2
Salvatore, L.3
D'Errico, I.4
Petruzzelli, M.5
Conca, P.6
Jiang, Z.Y.7
Calabresi, L.8
Parini, P.9
Moschetta, A.10
-
29
-
-
77950911589
-
Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo
-
Yasuda, T.; Grillot, D.; Billheimer, J.T.; Briand, F.; Delerive, P.; Huet, S.; Rader, D.J. Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo. Arterioscler. Thromb. Vasc. Biol. 2010, 30, 781-786.
-
(2010)
Arterioscler. Thromb. Vasc. Biol
, vol.30
, pp. 781-786
-
-
Yasuda, T.1
Grillot, D.2
Billheimer, J.T.3
Briand, F.4
Delerive, P.5
Huet, S.6
Rader, D.J.7
-
30
-
-
33845587711
-
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
-
Chen, W.; Chen, G.; Head, D.L.; Mangelsdorf, D.J.; Russell, D.W. Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab. 2007, 5, 73-79.
-
(2007)
Cell Metab
, vol.5
, pp. 73-79
-
-
Chen, W.1
Chen, G.2
Head, D.L.3
Mangelsdorf, D.J.4
Russell, D.W.5
-
31
-
-
80052965098
-
Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo
-
Shafaati, M.; Olin, M.; Bavner, A.; Pettersson, H.; Rozell, B.; Meaney, S.; Parini, P.; Björkhem, I. Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. J. Intern. Med. 2011, 270, 377-387.
-
(2011)
J. Intern. Med
, vol.270
, pp. 377-387
-
-
Shafaati, M.1
Olin, M.2
Bavner, A.3
Pettersson, H.4
Rozell, B.5
Meaney, S.6
Parini, P.7
Björkhem, I.8
-
32
-
-
10044271037
-
SREBP transcription factors: Master regulators of lipid homeostasis
-
Eberle, D.; Hegarty, B.; Bossard, P.; Ferre, P.; Foufelle, F. SREBP transcription factors: Master regulators of lipid homeostasis. Biochimie 2004, 86, 839-848.
-
(2004)
Biochimie
, vol.86
, pp. 839-848
-
-
Eberle, D.1
Hegarty, B.2
Bossard, P.3
Ferre, P.4
Foufelle, F.5
-
33
-
-
30344473341
-
Protein sensors for membrane sterols
-
Goldstein, J.L.; DeBose-Boyd, R.A.; Brown, M.S. Protein sensors for membrane sterols. Cell 2006, 124, 35-46.
-
(2006)
Cell
, vol.124
, pp. 35-46
-
-
Goldstein, J.L.1
DeBose-Boyd, R.A.2
Brown, M.S.3
-
34
-
-
10644239801
-
Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs
-
Adams, C.M.; Reitz, J.; De Brabander, J.K.; Feramisco, J.D.; Li, L.; Brown, M.S.; Goldstein, J.L. Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs. J. Biol. Chem. 2004, 279, 52772-52780.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 52772-52780
-
-
Adams, C.M.1
Reitz, J.2
De Brabander, J.K.3
Feramisco, J.D.4
Li, L.5
Brown, M.S.6
Goldstein, J.L.7
-
35
-
-
0036671360
-
Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism
-
Brown, A.J.; Sun, L.; Feramisco, J.D.; Brown, M.S.; Goldstein, J.L. Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism. Mol. Cell 2002, 10, 237-245.
-
(2002)
Mol. Cell
, vol.10
, pp. 237-245
-
-
Brown, A.J.1
Sun, L.2
Feramisco, J.D.3
Brown, M.S.4
Goldstein, J.L.5
-
36
-
-
34249848111
-
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig
-
Radhakrishnan, A.; Ikeda, Y.; Kwon, H.J.; Brown, M.S.; Goldstein, J.L. Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig. Proc. Natl. Acad. Sci. USA 2007, 104, 6511-6518.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6511-6518
-
-
Radhakrishnan, A.1
Ikeda, Y.2
Kwon, H.J.3
Brown, M.S.4
Goldstein, J.L.5
-
37
-
-
34249861927
-
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins
-
Sun, L.P.; Seemann, J.; Goldstein, J.L.; Brown, M.S. Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins. Proc. Natl. Acad. Sci. USA 2007, 104, 6519-6526.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6519-6526
-
-
Sun, L.P.1
Seemann, J.2
Goldstein, J.L.3
Brown, M.S.4
-
38
-
-
38349112601
-
Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase
-
Lange, Y.; Ory, D.S.; Ye, J.; Lanier, M.H.; Hsu, F.F.; Steck, T.L. Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase. J. Biol. Chem. 2008, 283, 1445-1455.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 1445-1455
-
-
Lange, Y.1
Ory, D.S.2
Ye, J.3
Lanier, M.H.4
Hsu, F.F.5
Steck, T.L.6
-
39
-
-
0019420840
-
Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide
-
Nelson, J.A.; Steckbeck, S.R.; Spencer, T.A. Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide. J. Biol. Chem. 1981, 256, 1067-1068.
-
(1981)
J. Biol. Chem
, vol.256
, pp. 1067-1068
-
-
Nelson, J.A.1
Steckbeck, S.R.2
Spencer, T.A.3
-
40
-
-
0035976936
-
The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols
-
Janowski, B.A.; Shan, B.; Russell, D.W. The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols. J. Biol. Chem. 2001, 276, 45408-45416.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 45408-45416
-
-
Janowski, B.A.1
Shan, B.2
Russell, D.W.3
-
41
-
-
0030064188
-
Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells
-
Mark, M.; Muller, P.; Maier, R.; Eisele, B. Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells. J. Lipid. Res. 1996, 37, 148-158.
-
(1996)
J. Lipid. Res
, vol.37
, pp. 148-158
-
-
Mark, M.1
Muller, P.2
Maier, R.3
Eisele, B.4
-
42
-
-
0033524420
-
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
-
Janowski, B.A.; Grogan, M.J.; Jones, S.A.; Wisely, G.B.; Kliewer, S.A.; Corey, E.J.; Mangelsdorf, D.J. Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. Proc. Natl. Acad. Sci. USA 1999, 96, 266-271.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 266-271
-
-
Janowski, B.A.1
Grogan, M.J.2
Jones, S.A.3
Wisely, G.B.4
Kliewer, S.A.5
Corey, E.J.6
Mangelsdorf, D.J.7
-
43
-
-
34247139296
-
Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol
-
Beyea, M.M.; Heslop, C.L.; Sawyez, C.G.; Edwards, J.Y.; Markle, J.G.; Hegele, R.A.; Huff, M.W. Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. J. Biol. Chem. 2007, 282, 5207-5216.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 5207-5216
-
-
Beyea, M.M.1
Heslop, C.L.2
Sawyez, C.G.3
Edwards, J.Y.4
Markle, J.G.5
Hegele, R.A.6
Huff, M.W.7
-
44
-
-
0142120095
-
Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:Lanosterol cyclase: A novel mechanism for the attenuation of foam cell formation
-
Rowe, A.H.; Argmann, C.A.; Edwards, J.Y.; Sawyez, C.G.; Morand, O.H.; Hegele, R.A.; Huff, M.W. Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: A novel mechanism for the attenuation of foam cell formation. Circ. Res. 2003, 93, 717-725.
-
(2003)
Circ. Res
, vol.93
, pp. 717-725
-
-
Rowe, A.H.1
Argmann, C.A.2
Edwards, J.Y.3
Sawyez, C.G.4
Morand, O.H.5
Hegele, R.A.6
Huff, M.W.7
-
45
-
-
34247381583
-
Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol
-
doi:10.1186/1476-511X-6-10
-
Wong, J.; Quinn, C.M.; Brown, A.J. Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol. Lipids Health Dis. 2007, 6, doi:10.1186/1476-511X-6-10.
-
(2007)
Lipids Health Dis
, vol.6
-
-
Wong, J.1
Quinn, C.M.2
Brown, A.J.3
-
46
-
-
38149138153
-
Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis
-
Wong, J.; Quinn, C.M.; Gelissen, I.C.; Brown, A.J. Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis. J. Biol. Chem. 2008, 283, 700-707.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 700-707
-
-
Wong, J.1
Quinn, C.M.2
Gelissen, I.C.3
Brown, A.J.4
-
47
-
-
36249006573
-
Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis
-
Wong, J.; Quinn, C.M.; Guillemin, G.; Brown, A.J. Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis. J. Neurochem. 2007, 103, 1764-1773.
-
(2007)
J. Neurochem
, vol.103
, pp. 1764-1773
-
-
Wong, J.1
Quinn, C.M.2
Guillemin, G.3
Brown, A.J.4
-
48
-
-
44849097130
-
Epoxycholesterol impairs cholesteryl ester hydrolysis in macrophage foam cells, resulting in decreased cholesterol efflux
-
Ouimet, M.; Wang, M.D.; Cadotte, N.; Ho, K.; Marcel, Y.L. Epoxycholesterol impairs cholesteryl ester hydrolysis in macrophage foam cells, resulting in decreased cholesterol efflux. Arterioscler. Thromb. Vasc. Biol. 2008, 28, 1144-1150.
-
(2008)
Arterioscler. Thromb. Vasc. Biol
, vol.28
, pp. 1144-1150
-
-
Ouimet, M.1
Wang, M.D.2
Cadotte, N.3
Ho, K.4
Marcel, Y.L.5
-
49
-
-
66849099394
-
Retinoid-related orphan receptors (RORs): Critical roles in development, immunity, circadian rhythm, and cellular metabolism
-
doi:10.1621/nrs.07003
-
Jetten, A.M. Retinoid-related orphan receptors (RORs): Critical roles in development, immunity, circadian rhythm, and cellular metabolism. Nucl. Recept. Signal. 2009, 7, doi:10.1621/nrs.07003.
-
(2009)
Nucl. Recept. Signal
, vol.7
-
-
Jetten, A.M.1
-
50
-
-
0036238332
-
Nuclear hormone receptors in T lymphocytes
-
Winoto, A.; Littman, D.R. Nuclear hormone receptors in T lymphocytes. Cell 2002, 109, S57-S66.
-
(2002)
Cell
, vol.109
-
-
Winoto, A.1
Littman, D.R.2
-
51
-
-
35548949049
-
Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism
-
Kang, H.S.; Angers, M.; Beak, J.Y.; Wu, X.; Gimble, J.M.; Wada, T.; Xie, W.; Collins, J.B.; Grissom, S.F.; Jetten, A.M. Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism. Physiol. Genomics 2007, 31, 281-294.
-
(2007)
Physiol. Genomics
, vol.31
, pp. 281-294
-
-
Kang, H.S.1
Angers, M.2
Beak, J.Y.3
Wu, X.4
Gimble, J.M.5
Wada, T.6
Xie, W.7
Collins, J.B.8
Grissom, S.F.9
Jetten, A.M.10
-
52
-
-
77951149298
-
Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands
-
Wang, Y.; Kumar, N.; Solt, L.A.; Richardson, T.I.; Helvering, L.M.; Crumbley, C.; Garcia-Ordonez, R.D.; Stayrook, K.R.; Zhang, X.; Novick, S.; Chalmers, M.J.; Griffin, P.R.; Burris, T.P. Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands. J. Biol. Chem. 2010, 285, 5013-5025.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 5013-5025
-
-
Wang, Y.1
Kumar, N.2
Solt, L.A.3
Richardson, T.I.4
Helvering, L.M.5
Crumbley, C.6
Garcia-Ordonez, R.D.7
Stayrook, K.R.8
Zhang, X.9
Novick, S.10
Chalmers, M.J.11
Griffin, P.R.12
Burris, T.P.13
-
53
-
-
77953243855
-
A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol)
-
Wang, Y.; Kumar, N.; Crumbley, C.; Griffin, P.R.; Burris, T.P. A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol). Biochim. Biophys. Acta 2010, 1801, 917-923.
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 917-923
-
-
Wang, Y.1
Kumar, N.2
Crumbley, C.3
Griffin, P.R.4
Burris, T.P.5
-
54
-
-
54549090146
-
The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno-and endobiotic gene regulation
-
Wada, T.; Kang, H.S.; Jetten, A.M.; Xie, W. The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno-and endobiotic gene regulation. Exp. Biol. Med. 2008, 233, 1191-1201.
-
(2008)
Exp. Biol. Med
, vol.233
, pp. 1191-1201
-
-
Wada, T.1
Kang, H.S.2
Jetten, A.M.3
Xie, W.4
-
55
-
-
35148833054
-
Deconstructing the hedgehog pathway in development and disease
-
Jacob, L.; Lum, L. Deconstructing the hedgehog pathway in development and disease. Science 2007, 318, 66-68.
-
(2007)
Science
, vol.318
, pp. 66-68
-
-
Jacob, L.1
Lum, L.2
-
57
-
-
33744788672
-
Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells
-
Corcoran, R.B.; Scott, M.P. Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells. Proc. Natl. Acad. Sci. USA 2006, 103, 8408-8413.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8408-8413
-
-
Corcoran, R.B.1
Scott, M.P.2
-
58
-
-
34247844371
-
Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells
-
Dwyer, J.R.; Sever, N.; Carlson, M.; Nelson, S.F.; Beachy, P.A.; Parhami, F. Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells. J. Biol. Chem. 2007, 282, 8959-8968.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 8959-8968
-
-
Dwyer, J.R.1
Sever, N.2
Carlson, M.3
Nelson, S.F.4
Beachy, P.A.5
Parhami, F.6
-
59
-
-
38449113816
-
20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism
-
Kim, W.K.; Meliton, V.; Amantea, C.M.; Hahn, T.J.; Parhami, F. 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism. J. Bone Miner. Res. 2007, 22, 1711-1719.
-
(2007)
J. Bone Miner. Res
, vol.22
, pp. 1711-1719
-
-
Kim, W.K.1
Meliton, V.2
Amantea, C.M.3
Hahn, T.J.4
Parhami, F.5
-
60
-
-
79954544086
-
Novel oxysterols have pro-osteogenic and anti-adipogenic effects in vitro and induce spinal fusion in vivo
-
Johnson, J.S.; Meliton, V.; Kim, W.K.; Lee, K.B.; Wang, J.C.; Nguyen, K.; Yoo, D.; Jung, M.E.; Atti, E.; Tetradis, S.; Pereira, R.C.; Magyar, C.; Nargizyan, T.; Hahn, T.J.; Farouz, F.; Thies, S.; Parhami, F. Novel oxysterols have pro-osteogenic and anti-adipogenic effects in vitro and induce spinal fusion in vivo. J. Cell. Biochem. 2011, 112, 1673-1684.
-
(2011)
J. Cell. Biochem
, vol.112
, pp. 1673-1684
-
-
Johnson, J.S.1
Meliton, V.2
Kim, W.K.3
Lee, K.B.4
Wang, J.C.5
Nguyen, K.6
Yoo, D.7
Jung, M.E.8
Atti, E.9
Tetradis, S.10
Pereira, R.C.11
Magyar, C.12
Nargizyan, T.13
Hahn, T.J.14
Farouz, F.15
Thies, S.16
Parhami, F.17
-
61
-
-
54849424320
-
Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling
-
Amantea, C.M.; Kim, W.K.; Meliton, V.; Tetradis, S.; Parhami, F. Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling. J. Cell. Biochem. 2008, 105, 424-436.
-
(2008)
J. Cell. Biochem
, vol.105
, pp. 424-436
-
-
Amantea, C.M.1
Kim, W.K.2
Meliton, V.3
Tetradis, S.4
Parhami, F.5
-
62
-
-
77953372061
-
Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells
-
Kim, W.K.; Meliton, V.; Tetradis, S.; Weinmaster, G.; Hahn, T.J.; Carlson, M.; Nelson, S.F.; Parhami, F. Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells. J. Bone Miner. Res. 2010, 25, 782-795.
-
(2010)
J. Bone Miner. Res
, vol.25
, pp. 782-795
-
-
Kim, W.K.1
Meliton, V.2
Tetradis, S.3
Weinmaster, G.4
Hahn, T.J.5
Carlson, M.6
Nelson, S.F.7
Parhami, F.8
-
63
-
-
84856098531
-
Oxysterols are allosteric activators of the oncoprotein Smoothened
-
Nachtergaele, S.; Mydock, L.K.; Krishnan, K.; Rammohan, J.; Schlesinger, P.H.; Covey, D.F.; Rohatgi, R. Oxysterols are allosteric activators of the oncoprotein Smoothened. Nat. Chem. Biol. 2012, 8, 211-220.
-
(2012)
Nat. Chem. Biol
, vol.8
, pp. 211-220
-
-
Nachtergaele, S.1
Mydock, L.K.2
Krishnan, K.3
Rammohan, J.4
Schlesinger, P.H.5
Covey, D.F.6
Rohatgi, R.7
-
64
-
-
33644638521
-
Estrogen receptors and human disease
-
Deroo, B.J.; Korach, K.S. Estrogen receptors and human disease. J. Clin. Invest. 2006, 116, 561-570.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 561-570
-
-
Deroo, B.J.1
Korach, K.S.2
-
65
-
-
0033542402
-
The protective effects of estrogen on the cardiovascular system
-
Mendelsohn, M.E.; Karas, R.H. The protective effects of estrogen on the cardiovascular system. N. Engl. J. Med. 1999, 340, 1801-1811.
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 1801-1811
-
-
Mendelsohn, M.E.1
Karas, R.H.2
-
66
-
-
35848931483
-
Cardioprotection in females: A role for nitric oxide and altered gene expression
-
Murphy, E.; Steenbergen, C. Cardioprotection in females: A role for nitric oxide and altered gene expression. Heart Fail. Rev. 2007, 12, 293-300.
-
(2007)
Heart Fail. Rev
, vol.12
, pp. 293-300
-
-
Murphy, E.1
Steenbergen, C.2
-
67
-
-
34948820661
-
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
-
Umetani, M.; Domoto, H.; Gormley, A.K.; Yuhanna, I.S.; Cummins, C.L.; Javitt, N.B.; Korach, K.S.; Shaul, P.W.; Mangelsdorf, D.J. 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nat. Med. 2007, 13, 1185-1192.
-
(2007)
Nat. Med
, vol.13
, pp. 1185-1192
-
-
Umetani, M.1
Domoto, H.2
Gormley, A.K.3
Yuhanna, I.S.4
Cummins, C.L.5
Javitt, N.B.6
Korach, K.S.7
Shaul, P.W.8
Mangelsdorf, D.J.9
-
68
-
-
38049008502
-
27-hydroxycholesterol is an endogenous selective estrogen receptor modulator
-
Dusell, C.D.; Umetani, M.; Shaul, P.W.; Mangelsdorf, D.J.; McDonnell, D.P. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol. Endocrinol. 2008, 22, 65-77.
-
(2008)
Mol. Endocrinol
, vol.22
, pp. 65-77
-
-
Dusell, C.D.1
Umetani, M.2
Shaul, P.W.3
Mangelsdorf, D.J.4
McDonnell, D.P.5
-
69
-
-
77954892925
-
The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis
-
DuSell, C.D.; Nelson, E.R.; Wang, X.; Abdo, J.; Modder, U.I.; Umetani, M.; Gesty-Palmer, D.; Javitt, N.B.; Khosla, S.; McDonnell, D.P. The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. Endocrinology 2010, 151, 3675-8365.
-
(2010)
Endocrinology
, vol.151
, pp. 3675-8365
-
-
DuSell, C.D.1
Nelson, E.R.2
Wang, X.3
Abdo, J.4
Modder, U.I.5
Umetani, M.6
Gesty-Palmer, D.7
Javitt, N.B.8
Khosla, S.9
McDonnell, D.P.10
-
70
-
-
82355163429
-
The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver x receptors
-
Nelson, E.R.; Dusell, C.D.; Wang, X.; Howe, M.K.; Evans, G.; Michalek, R.D.; Umetani, M.; Rathmell, J.C.; Khosla, S.; Gesty-Palmer, D.; McDonnell, D.P. The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver x receptors. Endocrinology 2011, 152, 4691-4705.
-
(2011)
Endocrinology
, vol.152
, pp. 4691-4705
-
-
Nelson, E.R.1
Dusell, C.D.2
Wang, X.3
Howe, M.K.4
Evans, G.5
Michalek, R.D.6
Umetani, M.7
Rathmell, J.C.8
Khosla, S.9
Gesty-Palmer, D.10
McDonnell, D.P.11
-
71
-
-
79958238550
-
27-hydroxycholesterol induces the transition of MCF7 cells into a mesenchymal phenotype
-
Torres, C.G.; Ramirez, M.E.; Cruz, P.; Epunan, M.J.; Valladares, L.E.; Sierralta, W.D. 27-hydroxycholesterol induces the transition of MCF7 cells into a mesenchymal phenotype. Oncol. Rep. 2011, 26, 389-397.
-
(2011)
Oncol. Rep
, vol.26
, pp. 389-397
-
-
Torres, C.G.1
Ramirez, M.E.2
Cruz, P.3
Epunan, M.J.4
Valladares, L.E.5
Sierralta, W.D.6
-
72
-
-
27744556268
-
Lipid microdomains and insulin resistance: Is there a connection?
-
doi:10.1126/stke.2682005pe3
-
Ikonen, E.; Vainio, S. Lipid microdomains and insulin resistance: Is there a connection? Sci. STKE 2005, 2005, doi:10.1126/stke.2682005pe3.
-
(2005)
Sci. STKE
, vol.2005
-
-
Ikonen, E.1
Vainio, S.2
-
73
-
-
41949099869
-
Dissecting lipid raft facilitated cell signaling pathways in cancer
-
Patra, S.K. Dissecting lipid raft facilitated cell signaling pathways in cancer. Biochim. Biophys. Acta 2008, 1785, 182-206.
-
(2008)
Biochim. Biophys. Acta
, vol.1785
, pp. 182-206
-
-
Patra, S.K.1
-
74
-
-
67349262029
-
Interactions of oxysterols with membranes and proteins
-
Olkkonen, V.M.; Hynynen, R. Interactions of oxysterols with membranes and proteins. Mol. Aspects Med. 2009, 30, 123-133.
-
(2009)
Mol. Aspects Med
, vol.30
, pp. 123-133
-
-
Olkkonen, V.M.1
Hynynen, R.2
-
75
-
-
34250308322
-
Apoptosis: A review of programmed cell death
-
Elmore, S. Apoptosis: A review of programmed cell death. Toxicol. Pathol. 2007, 35, 495-516.
-
(2007)
Toxicol. Pathol
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
76
-
-
0345505644
-
Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate
-
Monier, S.; Samadi, M.; Prunet, C.; Denance, M.; Laubriet, A.; Athias, A.; Berthier, A.; Steinmetz, E.; Jurgens, G.; Negre-Salvayre, A.; Bessede, G.; Lemaire-Ewing, S.; Neel, D.; Gambert, P.; Lizard, G. Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate. Biochem. Biophys. Res. Commun. 2003, 303, 814-824.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.303
, pp. 814-824
-
-
Monier, S.1
Samadi, M.2
Prunet, C.3
Denance, M.4
Laubriet, A.5
Athias, A.6
Berthier, A.7
Steinmetz, E.8
Jurgens, G.9
Negre-Salvayre, A.10
Bessede, G.11
Lemaire-Ewing, S.12
Neel, D.13
Gambert, P.14
Lizard, G.15
-
77
-
-
3042827082
-
Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: Implications for proatherogenic gene modulation
-
Biasi, F.; Leonarduzzi, G.; Vizio, B.; Zanetti, D.; Sevanian, A.; Sottero, B.; Verde, V.; Zingaro, B.; Chiarpotto, E.; Poli, G. Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: Implications for proatherogenic gene modulation. FASEB J. 2004, 18, 693-695.
-
(2004)
FASEB J
, vol.18
, pp. 693-695
-
-
Biasi, F.1
Leonarduzzi, G.2
Vizio, B.3
Zanetti, D.4
Sevanian, A.5
Sottero, B.6
Verde, V.7
Zingaro, B.8
Chiarpotto, E.9
Poli, G.10
-
78
-
-
1642422735
-
Trojan horse-like behavior of a biologically representative mixture of oxysterols
-
Leonarduzzi, G.; Biasi, F.; Chiarpotto, E.; Poli, G. Trojan horse-like behavior of a biologically representative mixture of oxysterols. Mol. Aspects Med. 2004, 25, 155-167.
-
(2004)
Mol. Aspects Med
, vol.25
, pp. 155-167
-
-
Leonarduzzi, G.1
Biasi, F.2
Chiarpotto, E.3
Poli, G.4
-
79
-
-
85016372604
-
7-ketocholesterol is not cytotoxic to U937 cells when incorporated into acetylated low density lipoprotein
-
(Epub ahead of print)
-
Rutherford, L.D.; Gieseg, S.P. 7-ketocholesterol is not cytotoxic to U937 cells when incorporated into acetylated low density lipoprotein. Lipids 2011, (Epub ahead of print).
-
(2011)
Lipids
-
-
Rutherford, L.D.1
Gieseg, S.P.2
-
80
-
-
0035008597
-
Fas/Fas ligand-mediated death pathway is involved in oxLDL-induced apoptosis in vascular smooth muscle cells
-
Lee, T.; Chau, L. Fas/Fas ligand-mediated death pathway is involved in oxLDL-induced apoptosis in vascular smooth muscle cells. Am. J. Physiol. Cell. Physiol. 2001, 280, C709-C718.
-
(2001)
Am. J. Physiol. Cell. Physiol
, vol.280
-
-
Lee, T.1
Chau, L.2
-
81
-
-
45949109637
-
Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis
-
Lordan, S.; Mackrill, J.J.; O'Brien, N.M. Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis. Int. J. Toxicol. 2008, 27, 279-285.
-
(2008)
Int. J. Toxicol
, vol.27
, pp. 279-285
-
-
Lordan, S.1
Mackrill, J.J.2
O'Brien, N.M.3
-
82
-
-
21344443874
-
TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol
-
Lee, H.S.; Chang, J.S.; Baek, J.A.; Chung, M.Y.; Lee, H.C.; Rhim, B.Y.; Sok, D.E.; Rho, M.C.; Kim, Y.K.; Kim, K. TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol. Biochem. Biophys. Res. Commun. 2005, 333, 1093-1099.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.333
, pp. 1093-1099
-
-
Lee, H.S.1
Chang, J.S.2
Baek, J.A.3
Chung, M.Y.4
Lee, H.C.5
Rhim, B.Y.6
Sok, D.E.7
Rho, M.C.8
Kim, Y.K.9
Kim, K.10
-
83
-
-
0037085365
-
Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes
-
Landis, M.S.; Patel, H.V.; Capone, J.P. Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes. J. Biol. Chem. 2002, 277, 4713-4721.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 4713-4721
-
-
Landis, M.S.1
Patel, H.V.2
Capone, J.P.3
-
84
-
-
33745788418
-
Multiplexed flow cytometric analyses of pro-and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients
-
Prunet, C.; Montange, T.; Vejux, A.; Laubriet, A.; Rohmer, J.F.; Riedinger, J.M.; Athias, A.; Lemaire-Ewing, S.; Neel, D.; Petit, J.M.; Steinmetz, E.; Brenot, R.; Gambert, P.; Lizard, G. Multiplexed flow cytometric analyses of pro-and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients. Cytom. A 2006, 69, 359-373.
-
(2006)
Cytom. A
, vol.69
, pp. 359-373
-
-
Prunet, C.1
Montange, T.2
Vejux, A.3
Laubriet, A.4
Rohmer, J.F.5
Riedinger, J.M.6
Athias, A.7
Lemaire-Ewing, S.8
Neel, D.9
Petit, J.M.10
Steinmetz, E.11
Brenot, R.12
Gambert, P.13
Lizard, G.14
-
85
-
-
33947106449
-
25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages
-
Erridge, C.; Webb, D.J.; Spickett, C.M. 25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages. Free Radic. Res. 2007, 41, 260-266.
-
(2007)
Free Radic. Res
, vol.41
, pp. 260-266
-
-
Erridge, C.1
Webb, D.J.2
Spickett, C.M.3
-
86
-
-
0032421830
-
Different patterns of IL-1beta secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7alpha-, 7beta-hydroxycholesterol, or 7-ketocholesterol
-
Lemaire, S.; Lizard, G.; Monier, S.; Miguet, C.; Gueldry, S.; Volot, F.; Gambert, P.; Neel, D. Different patterns of IL-1beta secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7alpha-, 7beta-hydroxycholesterol, or 7-ketocholesterol. FEBS Lett. 1998, 440, 434-439.
-
(1998)
FEBS Lett
, vol.440
, pp. 434-439
-
-
Lemaire, S.1
Lizard, G.2
Monier, S.3
Miguet, C.4
Gueldry, S.5
Volot, F.6
Gambert, P.7
Neel, D.8
-
87
-
-
32244433775
-
Regulation and interplay of apoptotic and non-apoptotic cell death
-
Kim, R.; Emi, M.; Tanabe, K.; Murakami, S.; Uchida, Y.; Arihiro, K. Regulation and interplay of apoptotic and non-apoptotic cell death. J. Pathol. 2006, 208, 319-326.
-
(2006)
J. Pathol
, vol.208
, pp. 319-326
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
Murakami, S.4
Uchida, Y.5
Arihiro, K.6
-
88
-
-
17644424665
-
Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide
-
Ryan, L.; O'Callaghan, Y.C.; O'Brien, N.M. Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. Cell Biol. Toxicol. 2004, 20, 313-323.
-
(2004)
Cell Biol. Toxicol
, vol.20
, pp. 313-323
-
-
Ryan, L.1
O'Callaghan, Y.C.2
O'Brien, N.M.3
-
89
-
-
0037098448
-
7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells
-
Ghelli, A.; Porcelli, A.M.; Zanna, C.; Rugolo, M. 7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells. Arch. Biochem. Biophys. 2002, 402, 208-217.
-
(2002)
Arch. Biochem. Biophys
, vol.402
, pp. 208-217
-
-
Ghelli, A.1
Porcelli, A.M.2
Zanna, C.3
Rugolo, M.4
-
90
-
-
77953535991
-
Tyrosine kinase inhibitor AG126 reduces 7-ketocholesterol-induced cell death by suppressing mitochondria-mediated apoptotic process
-
Kim, Y.J.; Lee, C.S. Tyrosine kinase inhibitor AG126 reduces 7-ketocholesterol-induced cell death by suppressing mitochondria-mediated apoptotic process. Neurochem. Res. 2010, 35, 603-612.
-
(2010)
Neurochem. Res
, vol.35
, pp. 603-612
-
-
Kim, Y.J.1
Lee, C.S.2
-
91
-
-
70349336667
-
Cholesterol secoaldehyde induces apoptosis in J774 macrophages via mitochondrial pathway but not involving reactive oxygen species as mediators
-
Gao, X.; Raghavamenon, A.C.; D'Auvergne, O.; Uppu, R.M. Cholesterol secoaldehyde induces apoptosis in J774 macrophages via mitochondrial pathway but not involving reactive oxygen species as mediators. Biochem. Biophys. Res. Commun. 2009, 389, 382-387.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.389
, pp. 382-387
-
-
Gao, X.1
Raghavamenon, A.C.2
D'Auvergne, O.3
Uppu, R.M.4
-
92
-
-
34247371033
-
Cell survival, cell death and cell cycle pathways are interconnected: Implications for cancer therapy
-
Maddika, S.; Ande, S.R.; Panigrahi, S.; Paranjothy, T.; Weglarczyk, K.; Zuse, A.; Eshraghi, M.; Manda, K.D.; Wiechec, E.; Los, M. Cell survival, cell death and cell cycle pathways are interconnected: Implications for cancer therapy. Drug Resist. Updat. 2007, 10, 13-29.
-
(2007)
Drug Resist. Updat
, vol.10
, pp. 13-29
-
-
Maddika, S.1
Ande, S.R.2
Panigrahi, S.3
Paranjothy, T.4
Weglarczyk, K.5
Zuse, A.6
Eshraghi, M.7
Manda, K.D.8
Wiechec, E.9
Los, M.10
-
93
-
-
34247120074
-
Redox regulation of 7-ketocholesterol-induced apoptosis by beta-carotene in human macrophages
-
Palozza, P.; Serini, S.; Verdecchia, S.; Ameruso, M.; Trombino, S.; Picci, N.; Monego, G.; Ranelletti, F.O. Redox regulation of 7-ketocholesterol-induced apoptosis by beta-carotene in human macrophages. Free Radic. Biol. Med. 2007, 42, 1579-1590.
-
(2007)
Free Radic. Biol. Med
, vol.42
, pp. 1579-1590
-
-
Palozza, P.1
Serini, S.2
Verdecchia, S.3
Ameruso, M.4
Trombino, S.5
Picci, N.6
Monego, G.7
Ranelletti, F.O.8
-
94
-
-
33644508080
-
Apoptotic effects of 25-hydroxycholesterol in immature rat Sertoli cells: Prevention by 17beta-estradiol
-
Le Goff, D.; Viville, C.; Carreau, S. Apoptotic effects of 25-hydroxycholesterol in immature rat Sertoli cells: Prevention by 17beta-estradiol. Reprod. Toxicol. 2006, 21, 329-334.
-
(2006)
Reprod. Toxicol
, vol.21
, pp. 329-334
-
-
Le Goff, D.1
Viville, C.2
Carreau, S.3
-
95
-
-
70349235462
-
Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia
-
doi:10.1155/2009/456208
-
Perales, S.; Alejandre, M.J.; Palomino-Morales, R.; Torres, C.; Iglesias, J.; Linares, A. Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia. J. Biomed. Biotechnol. 2009, 2009, doi:10.1155/2009/456208.
-
(2009)
J. Biomed. Biotechnol
, vol.2009
-
-
Perales, S.1
Alejandre, M.J.2
Palomino-Morales, R.3
Torres, C.4
Iglesias, J.5
Linares, A.6
-
96
-
-
33845733075
-
Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells
-
Roussi, S.; Gosse, F.; Aoude-Werner, D.; Zhang, X.; Marchioni, E.; Geoffroy, P.; Miesch, M.; Raul, F. Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells. Apoptosis 2007, 12, 87-96.
-
(2007)
Apoptosis
, vol.12
, pp. 87-96
-
-
Roussi, S.1
Gosse, F.2
Aoude-Werner, D.3
Zhang, X.4
Marchioni, E.5
Geoffroy, P.6
Miesch, M.7
Raul, F.8
-
97
-
-
70350153778
-
The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide
-
Lordan, S.; O'Brien, N.M.; Mackrill, J.J. The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. J. Biochem. Mol. Toxicol. 2009, 23, 324-332.
-
(2009)
J. Biochem. Mol. Toxicol
, vol.23
, pp. 324-332
-
-
Lordan, S.1
O'Brien, N.M.2
Mackrill, J.J.3
-
98
-
-
73649095857
-
7-ketocholesterol and 5,6-secosterol modulate differently the stress-activated mitogen-activated protein kinases (MAPKs) in liver cells
-
Anticoli, S.; Arciello, M.; Mancinetti, A.; de Martinis, M.; Ginaldi, L.; Iuliano, L.; Balsano, C. 7-ketocholesterol and 5,6-secosterol modulate differently the stress-activated mitogen-activated protein kinases (MAPKs) in liver cells. J. Cell. Physiol. 2010, 222, 586-595.
-
(2010)
J. Cell. Physiol
, vol.222
, pp. 586-595
-
-
Anticoli, S.1
Arciello, M.2
Mancinetti, A.3
de Martinis, M.4
Ginaldi, L.5
Iuliano, L.6
Balsano, C.7
-
99
-
-
78650414582
-
7-ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-kappaB and Akt pathways
-
Jang, E.R.; Lee, C.S. 7-ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-kappaB and Akt pathways. Neurochem. Int. 2011, 58, 52-59.
-
(2011)
Neurochem. Int
, vol.58
, pp. 52-59
-
-
Jang, E.R.1
Lee, C.S.2
-
100
-
-
80051546276
-
Lanthanum chloride suppresses oxysterol-induced ECV-304 cell apoptosis via inhibition of intracellular Ca(2+) concentration elevation, oxidative stress, and activation of ERK and NF-kappaB signaling pathways
-
Liu, H.; Zhang, C.; Huang, K. Lanthanum chloride suppresses oxysterol-induced ECV-304 cell apoptosis via inhibition of intracellular Ca(2+) concentration elevation, oxidative stress, and activation of ERK and NF-kappaB signaling pathways. J. Biol. Inorg. Chem. 2011, 16, 671-681.
-
(2011)
J. Biol. Inorg. Chem
, vol.16
, pp. 671-681
-
-
Liu, H.1
Zhang, C.2
Huang, K.3
-
101
-
-
78650916676
-
MAPK signaling in H9c2 cardiomyoblasts exposed to cholesterol secoaldehyde-Role of hydrogen peroxide
-
Laynes, L.; Raghavamenon, A.C.; D'Auvergne, O.; Achuthan, V.; Uppu, R.M. MAPK signaling in H9c2 cardiomyoblasts exposed to cholesterol secoaldehyde-Role of hydrogen peroxide. Biochem. Biophys. Res. Commun. 2011, 404, 90-95.
-
(2011)
Biochem. Biophys. Res. Commun
, vol.404
, pp. 90-95
-
-
Laynes, L.1
Raghavamenon, A.C.2
D'Auvergne, O.3
Achuthan, V.4
Uppu, R.M.5
-
102
-
-
65349111246
-
7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: Oxysterols-induced IL-8 secretion is calcium-dependent
-
Lemaire-Ewing, S.; Berthier, A.; Royer, M.C.; Logette, E.; Corcos, L.; Bouchot, A.; Monier, S.; Prunet, C.; Raveneau, M.; Rebe, C.; Desrumaux, C.; Lizard, G.; Neel, D. 7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: Oxysterols-induced IL-8 secretion is calcium-dependent. Cell Biol. Toxicol. 2009, 25, 127-139.
-
(2009)
Cell Biol. Toxicol
, vol.25
, pp. 127-139
-
-
Lemaire-Ewing, S.1
Berthier, A.2
Royer, M.C.3
Logette, E.4
Corcos, L.5
Bouchot, A.6
Monier, S.7
Prunet, C.8
Raveneau, M.9
Rebe, C.10
Desrumaux, C.11
Lizard, G.12
Neel, D.13
-
103
-
-
78650175733
-
Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: Effective protection by epigallocatechin-3-gallate
-
Mascia, C.; Maina, M.; Chiarpotto, E.; Leonarduzzi, G.; Poli, G.; Biasi, F. Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: Effective protection by epigallocatechin-3-gallate. Free Radic. Biol. Med. 2010, 49, 2049-2057.
-
(2010)
Free Radic. Biol. Med
, vol.49
, pp. 2049-2057
-
-
Mascia, C.1
Maina, M.2
Chiarpotto, E.3
Leonarduzzi, G.4
Poli, G.5
Biasi, F.6
-
104
-
-
78049373374
-
Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: Cytoprotective effects and prevention of VEGF secretion by resveratrol
-
Dugas, B.; Charbonnier, S.; Baarine, M.; Ragot, K.; Delmas, D.; Menetrier, F.; Lherminier, J.; Malvitte, L.; Khalfaoui, T.; Bron, A.; Creuzot-Garcher, C.; Latruffe, N.; Lizard, G. Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: Cytoprotective effects and prevention of VEGF secretion by resveratrol. Eur. J. Nutr. 2010, 49, 435-446.
-
(2010)
Eur. J. Nutr
, vol.49
, pp. 435-446
-
-
Dugas, B.1
Charbonnier, S.2
Baarine, M.3
Ragot, K.4
Delmas, D.5
Menetrier, F.6
Lherminier, J.7
Malvitte, L.8
Khalfaoui, T.9
Bron, A.10
Creuzot-Garcher, C.11
Latruffe, N.12
Lizard, G.13
-
105
-
-
77956800486
-
Cholesterol oxidation in the retina: Implications of 7KCh formation in chronic inflammation and age-related macular degeneration
-
Rodriguez, I.R.; Larrayoz, I.M. Cholesterol oxidation in the retina: Implications of 7KCh formation in chronic inflammation and age-related macular degeneration. J. Lipid Res. 2010, 51, 2847-2862.
-
(2010)
J. Lipid Res
, vol.51
, pp. 2847-2862
-
-
Rodriguez, I.R.1
Larrayoz, I.M.2
-
106
-
-
70349730033
-
25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production
-
Bauman, D.R.; Bitmansour, A.D.; McDonald, J.G.; Thompson, B.M.; Liang, G.; Russell, D.W. 25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production. Proc. Natl. Acad. Sci. USA 2009, 106, 16764-16769.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 16764-16769
-
-
Bauman, D.R.1
Bitmansour, A.D.2
McDonald, J.G.3
Thompson, B.M.4
Liang, G.5
Russell, D.W.6
-
107
-
-
78649752711
-
Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons
-
Park, K.; Scott, A.L. Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons. J. Leukoc. Biol. 2010, 88, 1081-1087.
-
(2010)
J. Leukoc. Biol
, vol.88
, pp. 1081-1087
-
-
Park, K.1
Scott, A.L.2
-
108
-
-
79960908110
-
Oxysterols direct B-cell migration through EBI2
-
Liu, C.; Yang, X.V.; Wu, J.; Kuei, C.; Mani, N.S.; Zhang, L.; Yu, J.; Sutton, S.W.; Qin, N.; Banie, H.; Karlsson, L.; Sun, S.; Lovenberg, T.W. Oxysterols direct B-cell migration through EBI2. Nature 2011, 475, 519-523.
-
(2011)
Nature
, vol.475
, pp. 519-523
-
-
Liu, C.1
Yang, X.V.2
Wu, J.3
Kuei, C.4
Mani, N.S.5
Zhang, L.6
Yu, J.7
Sutton, S.W.8
Qin, N.9
Banie, H.10
Karlsson, L.11
Sun, S.12
Lovenberg, T.W.13
-
109
-
-
79960909447
-
Oxysterols direct immune cell migration via EBI2
-
Hannedouche, S.; Zhang, J.; Yi, T.; Shen, W.; Nguyen, D.; Pereira, J.P.; Guerini, D.; Baumgarten, B.U.; Roggo, S.; Wen, B.; Knochenmuss, R.; Noel, S.; Gessier, F.; Kelly, L.M.; Vanek, M.; Laurent, S.; Preuss, I.; Miault, C.; Christen, I.; Karuna, R.; Li, W.; Koo, D.I.; Suply, T.; Schmedt, C.; Peters, E.C.; Falchetto, R.; Katopodis, A.; Spanka, C.; Roy, M.O.; Detheux, M.; Chen, Y.A.; Schultz, P.G.; Cho, C.Y.; Seuwen, K.; Cyster, J.G.; Sailer, A.W. Oxysterols direct immune cell migration via EBI2. Nature 2011, 475, 524-527.
-
(2011)
Nature
, vol.475
, pp. 524-527
-
-
Hannedouche, S.1
Zhang, J.2
Yi, T.3
Shen, W.4
Nguyen, D.5
Pereira, J.P.6
Guerini, D.7
Baumgarten, B.U.8
Roggo, S.9
Wen, B.10
Knochenmuss, R.11
Noel, S.12
Gessier, F.13
Kelly, L.M.14
Vanek, M.15
Laurent, S.16
Preuss, I.17
Miault, C.18
Christen, I.19
Karuna, R.20
Li, W.21
Koo, D.I.22
Suply, T.23
Schmedt, C.24
Peters, E.C.25
Falchetto, R.26
Katopodis, A.27
Spanka, C.28
Roy, M.O.29
Detheux, M.30
Chen, Y.A.31
Schultz, P.G.32
Cho, C.Y.33
Seuwen, K.34
Cyster, J.G.35
Sailer, A.W.36
more..
-
110
-
-
0038193542
-
Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages
-
Castrillo, A.; Joseph, S.B.; Marathe, C.; Mangelsdorf, D.J.; Tontonoz, P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J. Biol. Chem. 2003, 278, 10443-10449.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 10443-10449
-
-
Castrillo, A.1
Joseph, S.B.2
Marathe, C.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
111
-
-
63049122784
-
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
-
Ghisletti, S.; Huang, W.; Jepsen, K.; Benner, C.; Hardiman, G.; Rosenfeld, M.G.; Glass, C.K. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009, 23, 681-693.
-
(2009)
Genes Dev
, vol.23
, pp. 681-693
-
-
Ghisletti, S.1
Huang, W.2
Jepsen, K.3
Benner, C.4
Hardiman, G.5
Rosenfeld, M.G.6
Glass, C.K.7
-
112
-
-
0242361567
-
Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism
-
Castrillo, A.; Joseph, S.B.; Vaidya, S.A.; Haberland, M.; Fogelman, A.M.; Cheng, G.; Tontonoz, P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Mol. Cell 2003, 12, 805-816.
-
(2003)
Mol. Cell
, vol.12
, pp. 805-816
-
-
Castrillo, A.1
Joseph, S.B.2
Vaidya, S.A.3
Haberland, M.4
Fogelman, A.M.5
Cheng, G.6
Tontonoz, P.7
-
113
-
-
57849144598
-
TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis
-
Naiki, Y.; Sorrentino, R.; Wong, M.H.; Michelsen, K.S.; Shimada, K.; Chen, S.; Yilmaz, A.; Slepenkin, A.; Schroder, N.W.; Crother, T.R.; Bulut, Y.; Doherty, T.M.; Bradley, M.; Shaposhnik, Z.; Peterson, E.M.; Tontonoz, P.; Shah, P.K.; Arditi, M. TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. J. Immunol. 2008, 181, 7176-7185.
-
(2008)
J. Immunol
, vol.181
, pp. 7176-7185
-
-
Naiki, Y.1
Sorrentino, R.2
Wong, M.H.3
Michelsen, K.S.4
Shimada, K.5
Chen, S.6
Yilmaz, A.7
Slepenkin, A.8
Schroder, N.W.9
Crother, T.R.10
Bulut, Y.11
Doherty, T.M.12
Bradley, M.13
Shaposhnik, Z.14
Peterson, E.M.15
Tontonoz, P.16
Shah, P.K.17
Arditi, M.18
-
114
-
-
68949145931
-
Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR
-
A-Gonzalez, N.; Bensinger, S.J.; Hong, C.; Beceiro, S.; Bradley, M.N.; Zelcer, N.; Deniz, J.; Ramirez, C.; Diaz, M.; Gallardo, G.; de Galarreta, C.R.; Salazar, J.; Lopez, F.; Edwards, P.; Parks, J.; Andujar, M.; Tontonoz, P.; Castrillo, A. Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR. Immunity 2009, 31, 245-258.
-
(2009)
Immunity
, vol.31
, pp. 245-258
-
-
Gonzalez, A.N.1
Bensinger, S.J.2
Hong, C.3
Beceiro, S.4
Bradley, M.N.5
Zelcer, N.6
Deniz, J.7
Ramirez, C.8
Diaz, M.9
Gallardo, G.10
de Galarreta, C.R.11
Salazar, J.12
Lopez, F.13
Edwards, P.14
Parks, J.15
Andujar, M.16
Tontonoz, P.17
Castrillo, A.18
-
115
-
-
46149098344
-
LXR signaling couples sterol metabolism to proliferation in the acquired immune response
-
Bensinger, S.J.; Bradley, M.N.; Joseph, S.B.; Zelcer, N.; Janssen, E.M.; Hausner, M.A.; Shih, R.; Parks, J.S.; Edwards, P.A.; Jamieson, B.D.; Tontonoz, P. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell 2008, 134, 97-111.
-
(2008)
Cell
, vol.134
, pp. 97-111
-
-
Bensinger, S.J.1
Bradley, M.N.2
Joseph, S.B.3
Zelcer, N.4
Janssen, E.M.5
Hausner, M.A.6
Shih, R.7
Parks, J.S.8
Edwards, P.A.9
Jamieson, B.D.10
Tontonoz, P.11
-
116
-
-
4744363991
-
The pathophysiology and mechanisms of NP-C disease
-
Sturley, S.L.; Patterson, M.C.; Balch, W.; Liscum, L. The pathophysiology and mechanisms of NP-C disease. Biochim. Biophys. Acta 2004, 1685, 83-87.
-
(2004)
Biochim. Biophys. Acta
, vol.1685
, pp. 83-87
-
-
Sturley, S.L.1
Patterson, M.C.2
Balch, W.3
Liscum, L.4
-
117
-
-
78649916808
-
Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes
-
Wang, M.L.; Motamed, M.; Infante, R.E.; Abi-Mosleh, L.; Kwon, H.J.; Brown, M.S.; Goldstein, J.L. Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes. Cell. Metab. 2010, 12, 166-173.
-
(2010)
Cell. Metab
, vol.12
, pp. 166-173
-
-
Wang, M.L.1
Motamed, M.2
Infante, R.E.3
Abi-Mosleh, L.4
Kwon, H.J.5
Brown, M.S.6
Goldstein, J.L.7
-
118
-
-
78651328466
-
A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking
-
Du, X.; Kumar, J.; Ferguson, C.; Schulz, T.A.; Ong, Y.S.; Hong, W.; Prinz, W.A.; Parton, R.G.; Brown, A.J.; Yang, H. A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J. Cell Biol. 2011, 192, 121-135.
-
(2011)
J. Cell Biol
, vol.192
, pp. 121-135
-
-
Du, X.1
Kumar, J.2
Ferguson, C.3
Schulz, T.A.4
Ong, Y.S.5
Hong, W.6
Prinz, W.A.7
Parton, R.G.8
Brown, A.J.9
Yang, H.10
-
119
-
-
38149069055
-
Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein
-
Infante, R.E.; Abi-Mosleh, L.; Radhakrishnan, A.; Dale, J.D.; Brown, M.S.; Goldstein, J.L. Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein. J. Biol. Chem. 2008, 283, 1052-1063.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 1052-1063
-
-
Infante, R.E.1
Abi-Mosleh, L.2
Radhakrishnan, A.3
Dale, J.D.4
Brown, M.S.5
Goldstein, J.L.6
-
120
-
-
38149068309
-
Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop
-
Infante, R.E.; Radhakrishnan, A.; Abi-Mosleh, L.; Kinch, L.N.; Wang, M.L.; Grishin, N.V.; Goldstein, J.L.; Brown, M.S. Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop. J. Biol. Chem. 2008, 283, 1064-1075.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 1064-1075
-
-
Infante, R.E.1
Radhakrishnan, A.2
Abi-Mosleh, L.3
Kinch, L.N.4
Wang, M.L.5
Grishin, N.V.6
Goldstein, J.L.7
Brown, M.S.8
-
121
-
-
23744478870
-
Give lipids a START: The StAR-related lipid transfer (START) domain in mammals
-
Alpy, F.; Tomasetto, C. Give lipids a START: The StAR-related lipid transfer (START) domain in mammals. J. Cell. Sci. 2005, 118, 2791-2801.
-
(2005)
J. Cell. Sci
, vol.118
, pp. 2791-2801
-
-
Alpy, F.1
Tomasetto, C.2
-
122
-
-
23244431956
-
Human StarD5, a cytosolic StAR-related lipid binding protein
-
Rodriguez-Agudo, D.; Ren, S.; Hylemon, P.B.; Redford, K.; Natarajan, R.; Del Castillo, A.; Gil, G.; Pandak, W.M. Human StarD5, a cytosolic StAR-related lipid binding protein. J. Lipid Res. 2005, 46, 1615-1623.
-
(2005)
J. Lipid Res
, vol.46
, pp. 1615-1623
-
-
Rodriguez-Agudo, D.1
Ren, S.2
Hylemon, P.B.3
Redford, K.4
Natarajan, R.5
Del Castillo, A.6
Gil, G.7
Pandak, W.M.8
-
123
-
-
21444455252
-
Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress
-
Soccio, R.E.; Adams, R.M.; Maxwell, K.N.; Breslow, J.L. Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress. J. Biol. Chem. 2005, 280, 19410-19418.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 19410-19418
-
-
Soccio, R.E.1
Adams, R.M.2
Maxwell, K.N.3
Breslow, J.L.4
-
124
-
-
80051471035
-
Cytoplasmic oxysterol-binding proteins: Sterol sensors or transporters?
-
Vihervaara, T.; Jansen, M.; Uronen, R.L.; Ohsaki, Y.; Ikonen, E.; Olkkonen, V.M. Cytoplasmic oxysterol-binding proteins: Sterol sensors or transporters? Chem. Phys. Lipids 2011, 164, 443-450.
-
(2011)
Chem. Phys. Lipids
, vol.164
, pp. 443-450
-
-
Vihervaara, T.1
Jansen, M.2
Uronen, R.L.3
Ohsaki, Y.4
Ikonen, E.5
Olkkonen, V.M.6
-
125
-
-
33744728346
-
Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein
-
Perry, R.J.; Ridgway, N.D. Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein. Mol. Biol. Cell 2006, 17, 2604-2616.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2604-2616
-
-
Perry, R.J.1
Ridgway, N.D.2
-
126
-
-
78650123509
-
Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIalpha
-
Banerji, S.; Ngo, M.; Lane, C.F.; Robinson, C.A.; Minogue, S.; Ridgway, N.D. Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIalpha. Mol. Biol. Cell 2010, 21, 4141-4150.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 4141-4150
-
-
Banerji, S.1
Ngo, M.2
Lane, C.F.3
Robinson, C.A.4
Minogue, S.5
Ridgway, N.D.6
-
127
-
-
34247370976
-
Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis
-
Yan, D.; Lehto, M.; Rasilainen, L.; Metso, J.; Ehnholm, C.; Ylä-Herttuala, S.; Jauhiainen, M.; Olkkonen, V.M. Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis. Arterioscler. Thromb. Vasc. Biol. 2007, 27, 1108-1114.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 1108-1114
-
-
Yan, D.1
Lehto, M.2
Rasilainen, L.3
Metso, J.4
Ehnholm, C.5
Ylä-Herttuala, S.6
Jauhiainen, M.7
Olkkonen, V.M.8
-
128
-
-
30844437681
-
Docosahexaneoic acid (22:6, n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk-and 26S proteasome-dependent pathways
-
Botolin, D.; Wang, Y.; Christian, B.; Jump, D.B. Docosahexaneoic acid (22:6, n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk-and 26S proteasome-dependent pathways. J. Lipid Res. 2006, 47, 181-192.
-
(2006)
J. Lipid Res
, vol.47
, pp. 181-192
-
-
Botolin, D.1
Wang, Y.2
Christian, B.3
Jump, D.B.4
-
129
-
-
49649095715
-
OSBP negatively regulates ABCA1 protein stability
-
Bowden, K.; Ridgway, N.D. OSBP negatively regulates ABCA1 protein stability. J. Biol. Chem. 2008, 283, 18210-18217.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 18210-18217
-
-
Bowden, K.1
Ridgway, N.D.2
-
130
-
-
14644391519
-
OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation
-
Wang, P.Y.; Weng, J.; Anderson, R.G. OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation. Science 2005, 307, 1472-1476.
-
(2005)
Science
, vol.307
, pp. 1472-1476
-
-
Wang, P.Y.1
Weng, J.2
Anderson, R.G.3
-
131
-
-
43149086626
-
The N terminus controls sterol binding while the C terminus regulates the scaffolding function of OSBP
-
Wang, P.Y.; Weng, J.; Lee, S.; Anderson, R.G. The N terminus controls sterol binding while the C terminus regulates the scaffolding function of OSBP. J. Biol. Chem. 2008, 283, 8034-8045.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 8034-8045
-
-
Wang, P.Y.1
Weng, J.2
Lee, S.3
Anderson, R.G.4
-
132
-
-
44349141839
-
Oxysterol and diabetes activate STAT3, and control endothelial expression of profilin-1 via OSBP1
-
Romeo, G.R.; Kazlauskas, A. Oxysterol and diabetes activate STAT3, and control endothelial expression of profilin-1 via OSBP1. J Biol Chem 2008, 283, 9595-9605.
-
(2008)
J Biol Chem
, vol.283
, pp. 9595-9605
-
-
Romeo, G.R.1
Kazlauskas, A.2
-
133
-
-
33845698910
-
Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation
-
Lessmann, E.; Ngo, M.; Leitges, M.; Minguet, S.; Ridgway, N.D.; Huber, M. Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation. Cell Signal 2007, 19, 384-392.
-
(2007)
Cell Signal
, vol.19
, pp. 384-392
-
-
Lessmann, E.1
Ngo, M.2
Leitges, M.3
Minguet, S.4
Ridgway, N.D.5
Huber, M.6
-
134
-
-
42949170513
-
Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein
-
doi:10.1186/1750-1326-3-5
-
Zerbinatti, C.V.; Cordy, J.M.; Chen, C.D.; Guillily, M.; Suon, S.; Ray, W.J.; Seabrook, G.R.; Abraham, C.R.; Wolozin, B. Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein. Mol. Neurodegener 2008, 3, doi:10.1186/1750-1326-3-5.
-
(2008)
Mol. Neurodegener
, vol.3
-
-
Zerbinatti, C.V.1
Cordy, J.M.2
Chen, C.D.3
Guillily, M.4
Suon, S.5
Ray, W.J.6
Seabrook, G.R.7
Abraham, C.R.8
Wolozin, B.9
-
135
-
-
0026564767
-
Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding
-
Ridgway, N.D.; Dawson, P.A.; Ho, Y.K.; Brown, M.S.; Goldstein, J.L. Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding. J. Cell Biol. 1992, 116, 307-319.
-
(1992)
J. Cell Biol
, vol.116
, pp. 307-319
-
-
Ridgway, N.D.1
Dawson, P.A.2
Ho, Y.K.3
Brown, M.S.4
Goldstein, J.L.5
-
136
-
-
0034947717
-
Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells
-
Mohammadi, A.; Perry, R.J.; Storey, M.K.; Cook, H.W.; Byers, D.M.; Ridgway, N.D. Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells. J. Lipid Res. 2001, 42, 1062-1071.
-
(2001)
J. Lipid Res
, vol.42
, pp. 1062-1071
-
-
Mohammadi, A.1
Perry, R.J.2
Storey, M.K.3
Cook, H.W.4
Byers, D.M.5
Ridgway, N.D.6
-
137
-
-
77954204064
-
Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation
-
Nhek, S.; Ngo, M.; Yang, X.; Ng, M.M.; Field, S.J.; Asara, J.M.; Ridgway, N.D.; Toker, A. Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation. Mol. Biol. Cell 2010, 21, 2327-2337.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2327-2337
-
-
Nhek, S.1
Ngo, M.2
Yang, X.3
Ng, M.M.4
Field, S.J.5
Asara, J.M.6
Ridgway, N.D.7
Toker, A.8
-
138
-
-
69549113556
-
Role of oxysterol binding protein in hepatitis C virus infection
-
Amako, Y.; Sarkeshik, A.; Hotta, H.; Yates, J., 3rd; Siddiqui, A. Role of oxysterol binding protein in hepatitis C virus infection. J. Virol. 2009, 83, 9237-9246.
-
(2009)
J. Virol
, vol.83
, pp. 9237-9246
-
-
Amako, Y.1
Sarkeshik, A.2
Hotta, H.3
Yates III, J.4
Siddiqui, A.5
-
139
-
-
79953215325
-
Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein
-
Amako, Y.; Syed, G.H.; Siddiqui, A. Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein. J. Biol. Chem. 2011, 286, 11265-11274.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 11265-11274
-
-
Amako, Y.1
Syed, G.H.2
Siddiqui, A.3
-
140
-
-
84855984714
-
Oxysterol-binding protein (OSBP) enhances replication of intracellular Salmonella and binds the Salmonella SPI-2 effector SseL via its N-terminus
-
Auweter, S.D.; Yu, H.B.; Arena, E.T.; Guttman, J.A.; Finlay, B.B. Oxysterol-binding protein (OSBP) enhances replication of intracellular Salmonella and binds the Salmonella SPI-2 effector SseL via its N-terminus. Microbes Infect. 2011, 14, 148-154.
-
(2011)
Microbes Infect
, vol.14
, pp. 148-154
-
-
Auweter, S.D.1
Yu, H.B.2
Arena, E.T.3
Guttman, J.A.4
Finlay, B.B.5
-
141
-
-
38049136886
-
OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages
-
Yan, D.; Mäyränpää, M.I.; Wong, J.; Perttilä, J.; Lehto, M.; Jauhiainen, M.; Kovanen, P.T.; Ehnholm, C.; Brown, A.J.; Olkkonen, V.M. OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages. J. Biol. Chem. 2008, 283, 332-340.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 332-340
-
-
Yan, D.1
Mäyränpää, M.I.2
Wong, J.3
Perttilä, J.4
Lehto, M.5
Jauhiainen, M.6
Kovanen, P.T.7
Ehnholm, C.8
Brown, A.J.9
Olkkonen, V.M.10
-
142
-
-
79958859962
-
OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62
-
doi:10.1371/journal.pone.0021078
-
Zhou, T.; Li, S.; Zhong, W.; Vihervaara, T.; Beaslas, O.; Perttilä, J.; Luo, W.; Jiang, Y.; Lehto, M.; Olkkonen, V.M.; Yan, D. OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62. PLoS One 2011, 6, doi:10.1371/journal.pone.0021078.
-
(2011)
PLoS One
, vol.6
-
-
Zhou, T.1
Li, S.2
Zhong, W.3
Vihervaara, T.4
Beaslas, O.5
Perttilä, J.6
Luo, W.7
Jiang, Y.8
Lehto, M.9
Olkkonen, V.M.10
Yan, D.11
-
143
-
-
33847003020
-
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin
-
Johansson, M.; Rocha, N.; Zwart, W.; Jordens, I.; Janssen, L.; Kuijl, C.; Olkkonen, V.M.; Neefjes, J. Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin. J. Cell Biol. 2007, 176, 459-471.
-
(2007)
J. Cell Biol
, vol.176
, pp. 459-471
-
-
Johansson, M.1
Rocha, N.2
Zwart, W.3
Jordens, I.4
Janssen, L.5
Kuijl, C.6
Olkkonen, V.M.7
Neefjes, J.8
-
144
-
-
79951552363
-
Sterol binding by OSBP-related protein 1L regulates late endosome motility and function
-
Vihervaara, T.; Uronen, R.L.; Wohlfahrt, G.; Björkhem, I.; Ikonen, E.; Olkkonen, V.M. Sterol binding by OSBP-related protein 1L regulates late endosome motility and function. Cell. Mol. Life Sci. 2011, 68, 537-551.
-
(2011)
Cell. Mol. Life Sci
, vol.68
, pp. 537-551
-
-
Vihervaara, T.1
Uronen, R.L.2
Wohlfahrt, G.3
Björkhem, I.4
Ikonen, E.5
Olkkonen, V.M.6
-
145
-
-
67649600680
-
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning
-
Rocha, N.; Kuijl, C.; van der Kant, R.; Janssen, L.; Houben, D.; Janssen, H.; Zwart, W.; Neefjes, J. Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning. J. Cell Biol. 2009, 185, 1209-1225.
-
(2009)
J. Cell Biol
, vol.185
, pp. 1209-1225
-
-
Rocha, N.1
Kuijl, C.2
van der Kant, R.3
Janssen, L.4
Houben, D.5
Janssen, H.6
Zwart, W.7
Neefjes, J.8
-
146
-
-
33745755614
-
Inter-organelle membrane contact sites: Through a glass, darkly
-
Levine, T.; Loewen, C. Inter-organelle membrane contact sites: Through a glass, darkly. Curr. Opin. Cell Biol. 2006, 18, 371-378.
-
(2006)
Curr. Opin. Cell Biol
, vol.18
, pp. 371-378
-
-
Levine, T.1
Loewen, C.2
-
147
-
-
34250873397
-
Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice
-
Yan, D.; Jauhiainen, M.; Hildebrand, R.B.; van Dijk, K.W.; Van Berkel, T.J.C.; Ehnholm, C.; Van Eck, M.; Olkkonen, V.M. Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 2007, 27, 1618-1624.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 1618-1624
-
-
Yan, D.1
Jauhiainen, M.2
Hildebrand, R.B.3
van Dijk, K.W.4
Van Berkel, T.J.C.5
Ehnholm, C.6
Van Eck, M.7
Olkkonen, V.M.8
-
148
-
-
33645727511
-
Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides
-
Raychaudhuri, S.; Im, Y.J.; Hurley, J.H.; Prinz, W.A. Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides. J. Cell Biol. 2006, 173, 107-119.
-
(2006)
J. Cell Biol
, vol.173
, pp. 107-119
-
-
Raychaudhuri, S.1
Im, Y.J.2
Hurley, J.H.3
Prinz, W.A.4
-
149
-
-
33745475883
-
Sterol trafficking between the endoplasmic reticulum and plasma membrane in yeast
-
Sullivan, D.P.; Ohvo-Rekila, H.; Baumann, N.A.; Beh, C.T.; Menon, A.K. Sterol trafficking between the endoplasmic reticulum and plasma membrane in yeast. Biochem. Soc. Trans. 2006, 34, 356-358.
-
(2006)
Biochem. Soc. Trans
, vol.34
, pp. 356-358
-
-
Sullivan, D.P.1
Ohvo-Rekila, H.2
Baumann, N.A.3
Beh, C.T.4
Menon, A.K.5
-
150
-
-
80052630805
-
Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM
-
Georgiev, A.G.; Sullivan, D.P.; Kersting, M.C.; Dittman, J.S.; Beh, C.T.; Menon, A.K. Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM. Traffic 2011, 12, 1341-1355.
-
(2011)
Traffic
, vol.12
, pp. 1341-1355
-
-
Georgiev, A.G.1
Sullivan, D.P.2
Kersting, M.C.3
Dittman, J.S.4
Beh, C.T.5
Menon, A.K.6
-
151
-
-
65249161758
-
Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function
-
Ngo, M.; Ridgway, N.D. Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function. Mol. Biol. Cell 2009, 20, 1388-1399.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1388-1399
-
-
Ngo, M.1
Ridgway, N.D.2
-
152
-
-
78651076417
-
Role of ORPs in sterol transport from plasma membrane to ER and lipid droplets in mammalian cells
-
Jansen, M.; Ohsaki, Y.; Rita Rega, L.; Bittman, R.; Olkkonen, V.M.; Ikonen, E. Role of ORPs in sterol transport from plasma membrane to ER and lipid droplets in mammalian cells. Traffic 2011, 12, 218-231.
-
(2011)
Traffic
, vol.12
, pp. 218-231
-
-
Jansen, M.1
Ohsaki, Y.2
Rita Rega, L.3
Bittman, R.4
Olkkonen, V.M.5
Ikonen, E.6
-
153
-
-
34249299703
-
An experimentally derived database of candidate Ras-interacting proteins
-
Goldfinger, L.E.; Ptak, C.; Jeffery, E.D.; Shabanowitz, J.; Han, J.; Haling, J.R.; Sherman, N.E.; Fox, J.W.; Hunt, D.F.; Ginsberg, M.H. An experimentally derived database of candidate Ras-interacting proteins. J. Proteome Res. 2007, 6, 1806-1811.
-
(2007)
J. Proteome Res
, vol.6
, pp. 1806-1811
-
-
Goldfinger, L.E.1
Ptak, C.2
Jeffery, E.D.3
Shabanowitz, J.4
Han, J.5
Haling, J.R.6
Sherman, N.E.7
Fox, J.W.8
Hunt, D.F.9
Ginsberg, M.H.10
-
154
-
-
42149161113
-
The R-Ras interaction partner ORP3 regulates cell adhesion
-
Lehto, M.; Mäyränpää, M.I.; Pellinen, T.; P., I.; Lehtonen, S.; Kovanen, P.T.; Groop, P.H.; Ivaska, J.; Olkkonen, V.M. The R-Ras interaction partner ORP3 regulates cell adhesion. J. Cell Sci. 2008, 121, 695-705.
-
(2008)
J. Cell Sci
, vol.121
, pp. 695-705
-
-
Lehto, M.1
Mäyränpää, M.I.2
Pellinen, T.P.I.3
Lehtonen, S.4
Kovanen, P.T.5
Groop, P.H.6
Ivaska, J.7
Olkkonen, V.M.8
-
155
-
-
0029803610
-
Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis
-
Fang, M.; Kearns, B.G.; Gedvilaite, A.; Kagiwada, S.; Kearns, M.; Fung, M.K.; Bankaitis, V.A. Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. EMBO J. 1996, 15, 6447-6459.
-
(1996)
EMBO J
, vol.15
, pp. 6447-6459
-
-
Fang, M.1
Kearns, B.G.2
Gedvilaite, A.3
Kagiwada, S.4
Kearns, M.5
Fung, M.K.6
Bankaitis, V.A.7
-
156
-
-
0036544518
-
Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex
-
Li, X.; Rivas, M.P.; Fang, M.; Marchena, J.; Mehrotra, B.; Chaudhary, A.; Feng, L.; Prestwich, G.D.; Bankaitis, V.A. Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. J. Cell Biol. 2002, 157, 63-77.
-
(2002)
J. Cell Biol
, vol.157
, pp. 63-77
-
-
Li, X.1
Rivas, M.P.2
Fang, M.3
Marchena, J.4
Mehrotra, B.5
Chaudhary, A.6
Feng, L.7
Prestwich, G.D.8
Bankaitis, V.A.9
-
157
-
-
34848818827
-
The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function
-
Fairn, G.D.; Curwin, A.J.; Stefan, C.J.; McMaster, C.R. The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function. Proc. Natl. Acad. Sci. USA 2007, 104, 15352-15357.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 15352-15357
-
-
Fairn, G.D.1
Curwin, A.J.2
Stefan, C.J.3
McMaster, C.R.4
-
158
-
-
80053594641
-
The sterol-binding protein Kes1/Osh4p is a regulator of polarized exocytosis
-
Alfaro, G.; Johansen, J.; Dighe, S.A.; Duamel, G.; Kozminski, K.G.; Beh, C.T. The sterol-binding protein Kes1/Osh4p is a regulator of polarized exocytosis. Traffic 2011, 12, 1521-1536.
-
(2011)
Traffic
, vol.12
, pp. 1521-1536
-
-
Alfaro, G.1
Johansen, J.2
Dighe, S.A.3
Duamel, G.4
Kozminski, K.G.5
Beh, C.T.6
-
159
-
-
84855474121
-
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers
-
De Saint-Jean, M.; Delfosse, V.; Douguet, D.; Chicanne, G.; Payrastre, B.; Bourguet, W.; Antonny, B.; Drin, G. Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J. Cell Biol. 2011, 195, 965-978.
-
(2011)
J. Cell Biol
, vol.195
, pp. 965-978
-
-
De Saint-Jean, M.1
Delfosse, V.2
Douguet, D.3
Chicanne, G.4
Payrastre, B.5
Bourguet, W.6
Antonny, B.7
Drin, G.8
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