메뉴 건너뛰기




Volumn 24, Issue 21, 2015, Pages 5965-5976

Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with alzheimer-like Tau pathology

(21)  Burlot, Marie Anne a,b,c   Braudeau, Jérôme a,b   Michaelsen Preusse, Kristin d,e   Potier, Brigitte f   Ayciriex, Sophie g   Varin, Jennifer c   Gautier, Benoit a,b   Djelti, Fathia a,b,c   Audrain, Mickael a,b,c   Dauphinot, Luce h   Fernandez Gomez, Francisco Jose i,j   Caillierez, Raphaëlle i,j   Laprévote, Olivier g   Bièche, Ivan c   Auzeil, Nicolas g   Potier, Marie Claude h   Dutar, Patrick f   Korte, Martin d,e   Buée, Luc i,j,k   Blum, David i,j,k   more..


Author keywords

[No Author keywords available]

Indexed keywords

24 HYDROXYCHOLESTEROL; AMYLOID PROTEIN; CHOLESTEROL; CHOLESTEROL 24 HYDROXYLASE; OXYGENASE; PARVOVIRUS VECTOR; TAU PROTEIN; UNCLASSIFIED DRUG; 24-HYDROXYCHOLESTEROL; CHOLESTEROL 24-HYDROXYLASE; CHOLESTEROL DERIVATIVE; STEROID MONOOXYGENASE;

EID: 84949256198     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv268     Document Type: Article
Times cited : (96)

References (66)
  • 2
    • 0033850407 scopus 로고    scopus 로고
    • Tau protein isoforms, phosphorylation and role in neurodegenerative disorders Brain Res
    • Buee, L., Bussiere, T., Buee-Scherrer, V., Delacourte, A. and Hof, P.R. (2000) Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res. Brain Res. Rev., 33, 95-130.
    • (2000) Brain Res. Rev. , vol.33 , pp. 95-130
    • Buee, L.1    Bussiere, T.2    Buee-Scherrer, V.3    Delacourte, A.4    Hof, P.R.5
  • 8
    • 84872620881 scopus 로고    scopus 로고
    • NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model
    • Burnouf, S., Martire, A., Derisbourg, M., Laurent, C., Belarbi, K., Leboucher, A., Fernandez-Gomez, F.J., Troquier, L., Eddarkaoui, S., Grosjean, M.E. et al. (2013) NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model. Aging Cell, 12, 11-23.
    • (2013) Aging Cell , vol.12 , pp. 11-23
    • Burnouf, S.1    Martire, A.2    Derisbourg, M.3    Laurent, C.4    Belarbi, K.5    Leboucher, A.6    Fernandez-Gomez, F.J.7    Troquier, L.8    Eddarkaoui, S.9    Grosjean, M.E.10
  • 10
    • 69449093036 scopus 로고    scopus 로고
    • Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology
    • Polydoro, M., Acker, C.M., Duff, K., Castillo, P.E. and Davies, P. (2009) Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology. J. Neurosci., 29, 10741-10749.
    • (2009) J. Neurosci. , vol.29 , pp. 10741-10749
    • Polydoro, M.1    Acker, C.M.2    Duff, K.3    Castillo, P.E.4    Davies, P.5
  • 12
    • 84907952097 scopus 로고    scopus 로고
    • PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments
    • Hippocampus, in press
    • Chaalal, A., Poirier, R., Blum, D., Gillet, B., Le Blanc, P., Basquin, M., Buee, L., Laroche, S. and Enderlin, V. (2014) PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments. Hippocampus, in press.
    • (2014)
    • Chaalal, A.1    Poirier, R.2    Blum, D.3    Gillet, B.4    Le Blanc, P.5    Basquin, M.6    Buee, L.7    Laroche, S.8    Enderlin, V.9
  • 13
    • 79952629918 scopus 로고    scopus 로고
    • Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission
    • Van der Jeugd, A., Ahmed, T., Burnouf, S., Belarbi, K., Hamdame, M., Grosjean, M.E., Humez, S., Balschun, D., Blum, D., Buee, L. et al. (2011) Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. Neurobiol. Learn. Mem., 95, 296-304.
    • (2011) Neurobiol. Learn. Mem. , vol.95 , pp. 296-304
    • Van der Jeugd, A.1    Ahmed, T.2    Burnouf, S.3    Belarbi, K.4    Hamdame, M.5    Grosjean, M.E.6    Humez, S.7    Balschun, D.8    Blum, D.9    Buee, L.10
  • 14
    • 0345669752 scopus 로고    scopus 로고
    • Alzheimer's disease: the cholesterol connection
    • Puglielli, L., Tanzi, R.E. and Kovacs, D.M. (2003) Alzheimer's disease: the cholesterol connection. Nature Neurosci., 6, 345-351.
    • (2003) Nature Neurosci , vol.6 , pp. 345-351
    • Puglielli, L.1    Tanzi, R.E.2    Kovacs, D.M.3
  • 15
    • 2442684094 scopus 로고    scopus 로고
    • Cholesterol and APOE genotype interact to influence Alzheimer disease progression
    • Evans, R.M., Hui, S., Perkins, A., Lahiri, D.K., Poirier, J. and Farlow, M.R. (2004) Cholesterol and APOE genotype interact to influence Alzheimer disease progression. Neurology, 62, 1869-1871.
    • (2004) Neurology , vol.62 , pp. 1869-1871
    • Evans, R.M.1    Hui, S.2    Perkins, A.3    Lahiri, D.K.4    Poirier, J.5    Farlow, M.R.6
  • 16
    • 67349270965 scopus 로고    scopus 로고
    • Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
    • Bu, G. (2009) Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy. Nature Rev. Neurosci., 10, 333-344.
    • (2009) Nature Rev. Neurosci. , vol.10 , pp. 333-344
    • Bu, G.1
  • 17
    • 68249134074 scopus 로고    scopus 로고
    • The role of apolipoprotein E in Alzheimer's disease
    • Kim, J., Basak, J.M. and Holtzman, D.M. (2009) The role of apolipoprotein E in Alzheimer's disease. Neuron, 63, 287-303.
    • (2009) Neuron , vol.63 , pp. 287-303
    • Kim, J.1    Basak, J.M.2    Holtzman, D.M.3
  • 18
    • 33751096969 scopus 로고    scopus 로고
    • Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain
    • Bjorkhem, I. (2006) Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. J. Intern. Med., 260, 493-508.
    • (2006) J. Intern. Med. , vol.260 , pp. 493-508
    • Bjorkhem, I.1
  • 19
    • 0033594903 scopus 로고    scopus 로고
    • cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
    • Lund, E.G., Guileyardo, J.M. and Russell, D.W. (1999) cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. Proc. Natl. Acad. Sci. U.S.A., 96, 7238-7243.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 7238-7243
    • Lund, E.G.1    Guileyardo, J.M.2    Russell, D.W.3
  • 21
    • 84872340627 scopus 로고    scopus 로고
    • Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients
    • Lazar, A.N., Bich, C., Panchal, M., Desbenoit, N., Petit, V.W., Touboul, D., Dauphinot, L., Marquer, C., Laprevote, O., Brunelle, A. et al. (2013) Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients. Acta Neuropathol., 125, 133-144.
    • (2013) Acta Neuropathol , vol.125 , pp. 133-144
    • Lazar, A.N.1    Bich, C.2    Panchal, M.3    Desbenoit, N.4    Petit, V.W.5    Touboul, D.6    Dauphinot, L.7    Marquer, C.8    Laprevote, O.9    Brunelle, A.10
  • 22
    • 0034925263 scopus 로고    scopus 로고
    • Tangle-bearing neurons contain more free cholesterol than adjacent tangle-free neurons
    • Distl, R., Meske, V. and Ohm, T.G. (2001) Tangle-bearing neurons contain more free cholesterol than adjacent tangle-free neurons. Acta Neuropathol., 101, 547-554.
    • (2001) Acta Neuropathol , vol.101 , pp. 547-554
    • Distl, R.1    Meske, V.2    Ohm, T.G.3
  • 26
    • 67650432608 scopus 로고    scopus 로고
    • Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease
    • Solomon, A., Leoni, V., Kivipelto, M., Besga, A., Oksengard, A.R., Julin, P., Svensson, L., Wahlund, L.O., Andreasen, N., Winblad, B. et al. (2009) Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. Neurosci. Lett., 462, 89-93.
    • (2009) Neurosci. Lett. , vol.462 , pp. 89-93
    • Solomon, A.1    Leoni, V.2    Kivipelto, M.3    Besga, A.4    Oksengard, A.R.5    Julin, P.6    Svensson, L.7    Wahlund, L.O.8    Andreasen, N.9    Winblad, B.10
  • 29
    • 74149083432 scopus 로고    scopus 로고
    • Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease
    • Hudry, E., Van Dam, D., Kulik, W., De Deyn, P.P., Stet, F.S., Ahouansou, O., Benraiss, A., Delacourte, A., Bougneres, P., Aubourg, P. et al. (2010) Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. Mol. Ther., 18, 44-53.
    • (2010) Mol. Ther. , vol.18 , pp. 44-53
    • Hudry, E.1    Van Dam, D.2    Kulik, W.3    De Deyn, P.P.4    Stet, F.S.5    Ahouansou, O.6    Benraiss, A.7    Delacourte, A.8    Bougneres, P.9    Aubourg, P.10
  • 45
    • 84908091587 scopus 로고    scopus 로고
    • Liver X receptor agonist T0901317 reduces neuropathological changes and improves memory in mouse models of experimental dementia
    • Sodhi, R.K. and Singh, N. (2014) Liver X receptor agonist T0901317 reduces neuropathological changes and improves memory in mouse models of experimental dementia. Eur. J. Pharmacol., 732, 50-59.
    • (2014) Eur. J. Pharmacol. , vol.732 , pp. 50-59
    • Sodhi, R.K.1    Singh, N.2
  • 46
    • 77958594257 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice
    • Donkin, J.J., Stukas, S., Hirsch-Reinshagen, V., Namjoshi, D., Wilkinson, A., May, S., Chan, J., Fan, J., Collins, J. andWellington, C.L. (2010) ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice. J. Biol. Chem., 285, 34144-34154.
    • (2010) J. Biol. Chem. , vol.285 , pp. 34144-34154
    • Donkin, J.J.1    Stukas, S.2    Hirsch-Reinshagen, V.3    Namjoshi, D.4    Wilkinson, A.5    May, S.6    Chan, J.7    Fan, J.8    Collins, J.9    Wellington, C.L.10
  • 47
    • 77952630395 scopus 로고    scopus 로고
    • Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice
    • Fitz, N.F., Cronican, A., Pham, T., Fogg, A., Fauq, A.H., Chapman, R., Lefterov, I. and Koldamova, R. (2010) Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice. J. Neurosci., 30, 6862-6872.
    • (2010) J. Neurosci. , vol.30 , pp. 6862-6872
    • Fitz, N.F.1    Cronican, A.2    Pham, T.3    Fogg, A.4    Fauq, A.H.5    Chapman, R.6    Lefterov, I.7    Koldamova, R.8
  • 49
    • 80052965098 scopus 로고    scopus 로고
    • Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo
    • Shafaati, M., Olin, M., Bavner, A., Pettersson, H., Rozell, B., Meaney, S., Parini, P. and Bjorkhem, I. (2011) Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. J. Intern. Med., 270, 377-387.
    • (2011) J. Intern. Med. , vol.270 , pp. 377-387
    • Shafaati, M.1    Olin, M.2    Bavner, A.3    Pettersson, H.4    Rozell, B.5    Meaney, S.6    Parini, P.7    Bjorkhem, I.8
  • 50
    • 49649084975 scopus 로고    scopus 로고
    • Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation
    • Kotti, T., Head, D.D., McKenna, C.E. and Russell, D.W. (2008) Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. Proc. Natl. Acad. Sci. U.S.A., 105, 11394-11399.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 11394-11399
    • Kotti, T.1    Head, D.D.2    McKenna, C.E.3    Russell, D.W.4
  • 53
    • 84855798135 scopus 로고    scopus 로고
    • Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction
    • Alldred, M.J., Duff, K.E. and Ginsberg, S.D. (2012) Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction. Neurobiol. Dis., 45, 751-762.
    • (2012) Neurobiol. Dis. , vol.45 , pp. 751-762
    • Alldred, M.J.1    Duff, K.E.2    Ginsberg, S.D.3
  • 55
    • 33847163934 scopus 로고    scopus 로고
    • Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus
    • Kee, N., Teixeira, C.M., Wang, A.H. and Frankland, P.W. (2007) Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus. Nature Neurosci., 10, 355-362.
    • (2007) Nature Neurosci , vol.10 , pp. 355-362
    • Kee, N.1    Teixeira, C.M.2    Wang, A.H.3    Frankland, P.W.4
  • 57
    • 84872228584 scopus 로고    scopus 로고
    • Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia. Behav
    • Van der Jeugd, A., Blum, D., Raison, S., Eddarkaoui, S., Buee, L. and D'Hooge, R. (2013) Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia. Behav. Brain Res., 242, 34-39.
    • (2013) Brain Res , vol.242 , pp. 34-39
    • Van der Jeugd, A.1    Blum, D.2    Raison, S.3    Eddarkaoui, S.4    Buee, L.5    D'Hooge, R.6
  • 58
    • 33746652117 scopus 로고    scopus 로고
    • Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
    • Schindowski, K., Bretteville, A., Leroy, K., Begard, S., Brion, J.P., Hamdane, M. and Buee, L. (2006) Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. Am. J. Pathol., 169, 599-616.
    • (2006) Am. J. Pathol. , vol.169 , pp. 599-616
    • Schindowski, K.1    Bretteville, A.2    Leroy, K.3    Begard, S.4    Brion, J.P.5    Hamdane, M.6    Buee, L.7
  • 61
    • 84870866676 scopus 로고    scopus 로고
    • Development of a novel method for quantification of sterols and oxysterols by UPLC-ESI-HRMS: application to a neuroinflammation rat model
    • Ayciriex, S., Regazzetti, A., Gaudin, M., Prost, E., Dargere, D., Massicot, F., Auzeil, N. and Laprevote, O. (2012) Development of a novel method for quantification of sterols and oxysterols by UPLC-ESI-HRMS: application to a neuroinflammation rat model. Anal. Bioanal. Chem., 404, 3049-3059.
    • (2012) Anal. Bioanal. Chem. , vol.404 , pp. 3049-3059
    • Ayciriex, S.1    Regazzetti, A.2    Gaudin, M.3    Prost, E.4    Dargere, D.5    Massicot, F.6    Auzeil, N.7    Laprevote, O.8
  • 62
    • 4544242247 scopus 로고    scopus 로고
    • Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft microdomains: importance for excitatory amino acid transporter localization and function
    • Butchbach, M.E., Tian, G., Guo, H. and Lin, C.L. (2004) Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft microdomains: importance for excitatory amino acid transporter localization and function. J. Biol. Chem., 279, 34388-34396.
    • (2004) J. Biol. Chem. , vol.279 , pp. 34388-34396
    • Butchbach, M.E.1    Tian, G.2    Guo, H.3    Lin, C.L.4
  • 63
    • 0035866350 scopus 로고    scopus 로고
    • Identification of CGA as a novel estrogen receptor-responsive gene in breast cancer: an outstanding candidate marker to predict the response to endocrine therapy
    • Bieche, I., Parfait, B., Le Doussal, V., Olivi, M., Rio, M.C., Lidereau, R. and Vidaud, M. (2001) Identification of CGA as a novel estrogen receptor-responsive gene in breast cancer: an outstanding candidate marker to predict the response to endocrine therapy. Cancer Res., 61, 1652-1658.
    • (2001) Cancer Res , vol.61 , pp. 1652-1658
    • Bieche, I.1    Parfait, B.2    Le Doussal, V.3    Olivi, M.4    Rio, M.C.5    Lidereau, R.6    Vidaud, M.7
  • 64
    • 84555179176 scopus 로고    scopus 로고
    • Chronic treatment with a promnesiant GABA-A alpha5-selective inverse agonist increases immediate early genes expression during memory processing in mice and rectifies their expression levels in a down syndrome mouse model
    • Braudeau, J., Dauphinot, L., Duchon, A., Loistron, A., Dodd, R.H., Herault, Y., Delatour, B. and Potier, M.C. (2011) Chronic treatment with a promnesiant GABA-A alpha5-selective inverse agonist increases immediate early genes expression during memory processing in mice and rectifies their expression levels in a down syndrome mouse model. Adv. Pharmacol. Sci., 2011, 153218.
    • (2011) Adv. Pharmacol. Sci. , vol.2011
    • Braudeau, J.1    Dauphinot, L.2    Duchon, A.3    Loistron, A.4    Dodd, R.H.5    Herault, Y.6    Delatour, B.7    Potier, M.C.8
  • 65
    • 78349291932 scopus 로고    scopus 로고
    • Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats
    • Potier, B., Billard, J.M., Riviere, S., Sinet, P.M., Denis, I., Champeil-Potokar, G., Grintal, B., Jouvenceau, A., Kollen, M. and Dutar, P. (2010) Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats. Aging Cell, 9, 722-735.
    • (2010) Aging Cell , vol.9 , pp. 722-735
    • Potier, B.1    Billard, J.M.2    Riviere, S.3    Sinet, P.M.4    Denis, I.5    Champeil-Potokar, G.6    Grintal, B.7    Jouvenceau, A.8    Kollen, M.9    Dutar, P.10
  • 66
    • 78649713359 scopus 로고    scopus 로고
    • Neurotrophin receptors TrkB.T1 and p75NTR cooperate in modulating both functional and structural plasticity in mature hippocampal neurons
    • Michaelsen, K., Zagrebelsky, M., Berndt-Huch, J., Polack, M., Buschler, A., Sendtner, M. and Korte, M. (2010) Neurotrophin receptors TrkB.T1 and p75NTR cooperate in modulating both functional and structural plasticity in mature hippocampal neurons. Eur. J. Neurosci., 32, 1854-1865.
    • (2010) Eur. J. Neurosci. , vol.32 , pp. 1854-1865
    • Michaelsen, K.1    Zagrebelsky, M.2    Berndt-Huch, J.3    Polack, M.4    Buschler, A.5    Sendtner, M.6    Korte, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.