Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation

Journal of Lipid Research

Volumn 52, Issue 5, 2011, Pages 1004-1010

  Shafaati, Marjan ^a   Marutle, Amelia ^b   Pettersson, Hanna ^a   Lövgren Sandblom, Anita ^a   Olin, Maria ^a   Pikuleva, Irina ^c   Winblad, Bengt ^b   Nordberg, Agneta ^b   Björkhem, Ingemar ^a  

^a Department of Laboratory Medicine ^*  (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Cholesterol metabolism; Cytochrome P450; Oxysterols; Phytosterols

Indexed keywords

26 HYDROXYCHOLESTEROL; AMYLOID PRECURSOR PROTEIN; CAMPESTEROL; SITOSTEROL; SWEDISH AMYLOID PRECURSOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ALZHEIMER DISEASE; APPSWE GENE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN LEVEL; CASE REPORT; CHOLESTEROL METABOLISM; CONTROLLED STUDY; GENE; GENE MUTATION; HETEROZYGOTE; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; BLOTTING, WESTERN; BRAIN; CHOLESTEROL; FEMALE; HUMANS; HYDROXYCHOLESTEROLS; MALE; MIDDLE AGED; MUTATION; PHYTOSTEROLS; SITOSTEROLS;

EID: 79955038570     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M014548     Document Type: Article

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