메뉴 건너뛰기




Volumn 68, Issue , 2015, Pages 13-18

Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap?

Author keywords

Alpha synuclein; Alzheimer's disease; Endoplasmic reticulum stress; Oxysterols; Parkinson's disease

Indexed keywords

26 HYDROXYCHOLESTEROL; ALPHA SYNUCLEIN; CHOLESTEROL; OXYSTEROL; OXYSTEROL 26 HYDROXYCHOLESTEROL; UNCLASSIFIED DRUG; 27-HYDROXYCHOLESTEROL; CHOLESTEROL DERIVATIVE; CHOLESTEROL INTAKE; LIVER X RECEPTOR; ORPHAN NUCLEAR RECEPTOR;

EID: 84941313899     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2014.09.013     Document Type: Review
Times cited : (75)

References (47)
  • 1
    • 79960533372 scopus 로고    scopus 로고
    • Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases
    • Bazan N.G., Molina M.F., Gordon W.C. Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases. Annu. Rev. Nutr. 2011, 31:321-351.
    • (2011) Annu. Rev. Nutr. , vol.31 , pp. 321-351
    • Bazan, N.G.1    Molina, M.F.2    Gordon, W.C.3
  • 2
    • 0035985702 scopus 로고    scopus 로고
    • Oxysterols in human circulation: which role do they have?
    • Bjorkhem I., Meaney S., Diczfalusy U. Oxysterols in human circulation: which role do they have?. Curr. Opin. Lipidol. 2002, 13:247-253.
    • (2002) Curr. Opin. Lipidol. , vol.13 , pp. 247-253
    • Bjorkhem, I.1    Meaney, S.2    Diczfalusy, U.3
  • 3
    • 33646451063 scopus 로고    scopus 로고
    • Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization
    • Bosco D.A., Fowler D.M., Zhang Q., Nieva J., Powers E.T., Wentworth P., Lerner R.A., Kelly J.W. Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nat. Chem. Biol. 2006, 5:249-253.
    • (2006) Nat. Chem. Biol. , vol.5 , pp. 249-253
    • Bosco, D.A.1    Fowler, D.M.2    Zhang, Q.3    Nieva, J.4    Powers, E.T.5    Wentworth, P.6    Lerner, R.A.7    Kelly, J.W.8
  • 4
    • 0032890337 scopus 로고    scopus 로고
    • Oxysterols and atherosclerosis
    • Brown A.J., Jessup W. Oxysterols and atherosclerosis. Atherosclerosis 1999, 142:1-28.
    • (1999) Atherosclerosis , vol.142 , pp. 1-28
    • Brown, A.J.1    Jessup, W.2
  • 6
    • 42649109113 scopus 로고    scopus 로고
    • Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease
    • (Apr 3)
    • Chen X., Gawryluk J.W., Wagener J.F., Ghribi O., Geiger J.D. Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. J. Neuroinflammation 2008, 5:12. (Apr 3).
    • (2008) J. Neuroinflammation , vol.5 , pp. 12
    • Chen, X.1    Gawryluk, J.W.2    Wagener, J.F.3    Ghribi, O.4    Geiger, J.D.5
  • 7
    • 56749091143 scopus 로고    scopus 로고
    • Regulation of alpha-synuclein expression by liver X receptor ligands in vitro
    • Cheng D., Kim W.S., Garner B. Regulation of alpha-synuclein expression by liver X receptor ligands in vitro. Neuroreport 2008, 19:1685-1689.
    • (2008) Neuroreport , vol.19 , pp. 1685-1689
    • Cheng, D.1    Kim, W.S.2    Garner, B.3
  • 12
    • 0023764870 scopus 로고
    • Familial hypercholesterolemia and apolipoprotein E4
    • (Aug)
    • Eto M., Watanabe K., Chonan N., Ishii K. Familial hypercholesterolemia and apolipoprotein E4. Atherosclerosis 1988, 72(2-3):123-128. (Aug).
    • (1988) Atherosclerosis , vol.72 , Issue.2-3 , pp. 123-128
    • Eto, M.1    Watanabe, K.2    Chonan, N.3    Ishii, K.4
  • 13
    • 33749161414 scopus 로고    scopus 로고
    • Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets
    • Ghribi O., Golovko M.Y., Larsen B., Schrag M., Murphy E.J. Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets. J. Neurochem. 2006, 99(2):438-449.
    • (2006) J. Neurochem. , vol.99 , Issue.2 , pp. 438-449
    • Ghribi, O.1    Golovko, M.Y.2    Larsen, B.3    Schrag, M.4    Murphy, E.J.5
  • 14
    • 33746299216 scopus 로고    scopus 로고
    • High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus
    • Ghribi O., Larsen B., Schrag M., Herman M.M. High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus. Exp. Neurol. 2006, 200(2):460-467.
    • (2006) Exp. Neurol. , vol.200 , Issue.2 , pp. 460-467
    • Ghribi, O.1    Larsen, B.2    Schrag, M.3    Herman, M.M.4
  • 15
    • 0030032104 scopus 로고    scopus 로고
    • Phylogenetic position of the order Lagomorpha (rabbits, hares and allies)
    • Graur D., Duret L., Gouy M. Phylogenetic position of the order Lagomorpha (rabbits, hares and allies). Nature 1999, 379:333-335.
    • (1999) Nature , vol.379 , pp. 333-335
    • Graur, D.1    Duret, L.2    Gouy, M.3
  • 18
    • 77955941572 scopus 로고    scopus 로고
    • Total cholesterol and the risk of Parkinson's disease: a review for some new findings
    • Hu G. Total cholesterol and the risk of Parkinson's disease: a review for some new findings. Park. Dis. 2010, 2010:836962.
    • (2010) Park. Dis. , vol.2010 , pp. 836962
    • Hu, G.1
  • 19
    • 44949137294 scopus 로고    scopus 로고
    • Total cholesterol and the risk of Parkinson disease
    • (May 20)
    • Hu G., Antikainen R., Jousilahti P., Kivipelto M., Tuomilehto J. Total cholesterol and the risk of Parkinson disease. Neurology 2008, 70(21):1972-1979. (May 20).
    • (2008) Neurology , vol.70 , Issue.21 , pp. 1972-1979
    • Hu, G.1    Antikainen, R.2    Jousilahti, P.3    Kivipelto, M.4    Tuomilehto, J.5
  • 20
    • 80051603129 scopus 로고    scopus 로고
    • Parkinson Study Group DATATOP Investigators. Serum cholesterol and the progression of Parkinson's disease: results from DATATOP
    • Huang X., Auinger P., Eberly S., Oakes D., Schwarzschild M., Ascherio A., Mailman R., Chen H. Parkinson Study Group DATATOP Investigators. Serum cholesterol and the progression of Parkinson's disease: results from DATATOP. PLoS One 2011, 6(8):e22854.
    • (2011) PLoS One , vol.6 , Issue.8 , pp. e22854
    • Huang, X.1    Auinger, P.2    Eberly, S.3    Oakes, D.4    Schwarzschild, M.5    Ascherio, A.6    Mailman, R.7    Chen, H.8
  • 22
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski B.A., Willy P.J., Devi T.R., Falck J.R., Mangelsdorf D.J. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 1996, 383:728-731.
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 24
    • 0025853543 scopus 로고    scopus 로고
    • Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis
    • Johnstone E.M., Chaney M.O., Norris F.H., Pascual R., Little S.P. Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis. Brain Res. Mol. Brain Res. 1999, 10:299-305.
    • (1999) Brain Res. Mol. Brain Res. , vol.10 , pp. 299-305
    • Johnstone, E.M.1    Chaney, M.O.2    Norris, F.H.3    Pascual, R.4    Little, S.P.5
  • 25
    • 0035169488 scopus 로고    scopus 로고
    • Lewy body pathology in Alzheimer's disease
    • (Oct)
    • Kotzbauer P.T., Trojanowsk J.Q., Lee V.M. Lewy body pathology in Alzheimer's disease. J. Mol. Neurosci. 2001, 17(2):225-232. (Oct).
    • (2001) J. Mol. Neurosci. , vol.17 , Issue.2 , pp. 225-232
    • Kotzbauer, P.T.1    Trojanowsk, J.Q.2    Lee, V.M.3
  • 26
    • 0033384957 scopus 로고    scopus 로고
    • Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol
    • Lange Y., Ye J., Rigney M., Steck T.L. Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol. J. Lipid Res. 1999, 40:2264-2270.
    • (1999) J. Lipid Res. , vol.40 , pp. 2264-2270
    • Lange, Y.1    Ye, J.2    Rigney, M.3    Steck, T.L.4
  • 27
    • 0029835410 scopus 로고    scopus 로고
    • Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
    • Lutjohann D., Breuer O., Ahlborg G., Nennesmo I., Siden A., Diczfalusy U., Bjorkhem I. Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:9799-9804.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 9799-9804
    • Lutjohann, D.1    Breuer, O.2    Ahlborg, G.3    Nennesmo, I.4    Siden, A.5    Diczfalusy, U.6    Bjorkhem, I.7
  • 30
    • 77149145513 scopus 로고    scopus 로고
    • Leptin is involved in accumulation of amyloid-beta and tau phosphorylation induced by 27-hydroxycholesterol in organotypic slices from adult rabbit hippocampus
    • Marwarha G., Dasari B., Prasanthi J.R.P., Schommer J., Ghribi O. Leptin is involved in accumulation of amyloid-beta and tau phosphorylation induced by 27-hydroxycholesterol in organotypic slices from adult rabbit hippocampus. J. Alzheimers Dis. 2010, 19(3):1007-1019.
    • (2010) J. Alzheimers Dis. , vol.19 , Issue.3 , pp. 1007-1019
    • Marwarha, G.1    Dasari, B.2    Prasanthi, J.R.P.3    Schommer, J.4    Ghribi, O.5
  • 31
    • 81255157521 scopus 로고    scopus 로고
    • The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors - relevance to Parkinson's disease
    • (Dec)
    • Marwarha G., Rhen T., Schommer T., Ghribi O. The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors - relevance to Parkinson's disease. J. Neurochem. 2011, 119(5):1119-1136. (Dec).
    • (2011) J. Neurochem. , vol.119 , Issue.5 , pp. 1119-1136
    • Marwarha, G.1    Rhen, T.2    Schommer, T.3    Ghribi, O.4
  • 32
    • 83555172246 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol
    • (Feb)
    • Marwarha G., Dasari B., Ghribi O. Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol. Cell. Signal. 2012, 24(2):484-492. (Feb).
    • (2012) Cell. Signal. , vol.24 , Issue.2 , pp. 484-492
    • Marwarha, G.1    Dasari, B.2    Ghribi, O.3
  • 33
    • 84881258722 scopus 로고    scopus 로고
    • Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells
    • (Aug 9)
    • Marwarha G., Raza S., Prasanthi J.R., Ghribi O. Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells. PLoS One 2013, 8(8):e70773. (Aug 9).
    • (2013) PLoS One , vol.8 , Issue.8 , pp. e70773
    • Marwarha, G.1    Raza, S.2    Prasanthi, J.R.3    Ghribi, O.4
  • 35
    • 62149140601 scopus 로고    scopus 로고
    • Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells
    • Prasanthi J.R.P., Huls A., Thomasson S., Thompson A., Schommer E., Ghribi O. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. Mol. Neurodegener. 2009, 4:1.
    • (2009) Mol. Neurodegener. , vol.4 , pp. 1
    • Prasanthi, J.R.P.1    Huls, A.2    Thomasson, S.3    Thompson, A.4    Schommer, E.5    Ghribi, O.6
  • 36
    • 0142105914 scopus 로고    scopus 로고
    • Cholesterol: from heart attacks to Alzheimer's disease
    • (Aug)
    • Raffai R.L., Weisgraber K.H. Cholesterol: from heart attacks to Alzheimer's disease. J. Lipid Res. 2003, 44(8):1423-1430. (Aug).
    • (2003) J. Lipid Res. , vol.44 , Issue.8 , pp. 1423-1430
    • Raffai, R.L.1    Weisgraber, K.H.2
  • 37
    • 56749183934 scopus 로고    scopus 로고
    • Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells
    • Rantham Prabhakara J.P., Feist G., Thomasson S., Thompson A., Schommer E., Ghribi O. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. J. Neurochem. 2008, 107:1722-1729.
    • (2008) J. Neurochem. , vol.107 , pp. 1722-1729
    • Rantham Prabhakara, J.P.1    Feist, G.2    Thomasson, S.3    Thompson, A.4    Schommer, E.5    Ghribi, O.6
  • 38
    • 84893825608 scopus 로고    scopus 로고
    • Associations between serum cholesterol levels and cerebral amyloidosis
    • (Feb)
    • Reed B., Villeneuve S., Mack W., DeCarli C., Chui H.C., Jagust W. Associations between serum cholesterol levels and cerebral amyloidosis. JAMA Neurol. 2014, 71(2):195-200. (Feb).
    • (2014) JAMA Neurol. , vol.71 , Issue.2 , pp. 195-200
    • Reed, B.1    Villeneuve, S.2    Mack, W.3    DeCarli, C.4    Chui, H.C.5    Jagust, W.6
  • 40
    • 78650094288 scopus 로고    scopus 로고
    • Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease
    • (Dec)
    • Reitz C., Tang M.X., Schupf N., Manly J.J., Mayeux R., Luchsinger J.A. Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease. Arch. Neurol. 2010, 67(12):1491-1497. (Dec).
    • (2010) Arch. Neurol. , vol.67 , Issue.12 , pp. 1491-1497
    • Reitz, C.1    Tang, M.X.2    Schupf, N.3    Manly, J.J.4    Mayeux, R.5    Luchsinger, J.A.6
  • 41
    • 40849102760 scopus 로고    scopus 로고
    • Hippocampus of Ames dwarf mice is resistant to beta-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels
    • Schrag M., Sharma S., Brown-Borg H., Ghribi O. Hippocampus of Ames dwarf mice is resistant to beta-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels. Hippocampus 2008, 18(3):239-244.
    • (2008) Hippocampus , vol.18 , Issue.3 , pp. 239-244
    • Schrag, M.1    Sharma, S.2    Brown-Borg, H.3    Ghribi, O.4
  • 42
    • 84861088134 scopus 로고    scopus 로고
    • Dietary cholesterol concentration and duration degrade long-term memory of classical conditioning of the rabbit's nictitating membrane response
    • Schreurs B.G., Wang D., Smith-Bell C.A., Burhans L.B., Bell R., Gonzalez-Joekes J. Dietary cholesterol concentration and duration degrade long-term memory of classical conditioning of the rabbit's nictitating membrane response. Int. J. Alzheimers Dis. 2012, 2012:732634.
    • (2012) Int. J. Alzheimers Dis. , vol.2012 , pp. 732634
    • Schreurs, B.G.1    Wang, D.2    Smith-Bell, C.A.3    Burhans, L.B.4    Bell, R.5    Gonzalez-Joekes, J.6
  • 43
    • 56349160982 scopus 로고    scopus 로고
    • Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling
    • (Dec)
    • Sharma S., Prasanthi R.P.J., Schommer E., Feist G., Ghribi O. Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling. Neurobiol. Dis. 2008, 32(3):426-432. (Dec).
    • (2008) Neurobiol. Dis. , vol.32 , Issue.3 , pp. 426-432
    • Sharma, S.1    Prasanthi, R.P.J.2    Schommer, E.3    Feist, G.4    Ghribi, O.5
  • 44
    • 67749114631 scopus 로고    scopus 로고
    • Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later
    • Solomon A., Kivipelto M., Wolozin B., Zhou J., Whitmer R.A. Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later. Dement. Geriatr. Cogn. Disord. 2009, 28:75-80.
    • (2009) Dement. Geriatr. Cogn. Disord. , vol.28 , pp. 75-80
    • Solomon, A.1    Kivipelto, M.2    Wolozin, B.3    Zhou, J.4    Whitmer, R.A.5
  • 45
    • 0028177562 scopus 로고
    • Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
    • Sparks D.L., Scheff S.W., Hunsaker J.C., Liu H., Landers T., Gross D.R. Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp. Neurol. 1994, 126:88-94.
    • (1994) Exp. Neurol. , vol.126 , pp. 88-94
    • Sparks, D.L.1    Scheff, S.W.2    Hunsaker, J.C.3    Liu, H.4    Landers, T.5    Gross, D.R.6
  • 46
    • 33847072196 scopus 로고    scopus 로고
    • Effects of heme oxygenase-1 expression on sterol homeostasis in rat astroglia
    • (Mar 15)
    • Vaya J., Song W., Khatib S., Geng G., Schipper H.M. Effects of heme oxygenase-1 expression on sterol homeostasis in rat astroglia. Free Radic. Biol. Med. 2007, 42(6):864-871. (Mar 15).
    • (2007) Free Radic. Biol. Med. , vol.42 , Issue.6 , pp. 864-871
    • Vaya, J.1    Song, W.2    Khatib, S.3    Geng, G.4    Schipper, H.M.5
  • 47
    • 34247187959 scopus 로고    scopus 로고
    • Effects of paradigm and inter-stimulus interval on age differences in eyeblink classical conditioning in rabbits
    • (Apr 6)
    • Woodruff-Pak D.S., Seta S.E., Roker L.A., Lehr M.A. Effects of paradigm and inter-stimulus interval on age differences in eyeblink classical conditioning in rabbits. Learn. Mem. 2007, 14(4):287-294. (Apr 6).
    • (2007) Learn. Mem. , vol.14 , Issue.4 , pp. 287-294
    • Woodruff-Pak, D.S.1    Seta, S.E.2    Roker, L.A.3    Lehr, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.