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Volumn 155, Issue , 2016, Pages 10-21

Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis

Author keywords

HIF 1 ; Oxidative phosphorylation; PGC 1 ; Reactive oxygen species

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHRL1; HIF1A PROTEIN, HUMAN; PPARGC1A PROTEIN, HUMAN; SIRT1 PROTEIN, HUMAN;

EID: 84959559301     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2016.02.003     Document Type: Review
Times cited : (223)

References (140)
  • 2
    • 69249116960 scopus 로고    scopus 로고
    • SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD
    • Amat R., Planavila A., Chen S.L., Iglesias R., Giralt M., Villarroya F. SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. J. Biol. Chem. 2009, 284:1872-1880.
    • (2009) J. Biol. Chem. , vol.284 , pp. 1872-1880
    • Amat, R.1    Planavila, A.2    Chen, S.L.3    Iglesias, R.4    Giralt, M.5    Villarroya, F.6
  • 3
    • 77954353059 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis
    • Aquilano K., Vigilanza P., Baldelli S., Pagliei B., Rotilio G., Ciriolo M.R. Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J. Biol. Chem. 2010, 285:21590-21599.
    • (2010) J. Biol. Chem. , vol.285 , pp. 21590-21599
    • Aquilano, K.1    Vigilanza, P.2    Baldelli, S.3    Pagliei, B.4    Rotilio, G.5    Ciriolo, M.R.6
  • 4
    • 84878941111 scopus 로고    scopus 로고
    • Extranuclear localization of SIRT1 and PGC-1: an insight into possible roles in diseases associated with mitochondrial dysfunction
    • Aquilano K., Baldelli S., Pagliei B., Ciriolo M.R. Extranuclear localization of SIRT1 and PGC-1: an insight into possible roles in diseases associated with mitochondrial dysfunction. Curr. Mol. Med. 2013, 13:140-154.
    • (2013) Curr. Mol. Med. , vol.13 , pp. 140-154
    • Aquilano, K.1    Baldelli, S.2    Pagliei, B.3    Ciriolo, M.R.4
  • 5
    • 84891275812 scopus 로고    scopus 로고
    • Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1
    • Arunachalam G., Samuel S.M., Marei I., Ding H., Triggle C.R. Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1. Br. J. Pharmacol. 2014, 171:523-535.
    • (2014) Br. J. Pharmacol. , vol.171 , pp. 523-535
    • Arunachalam, G.1    Samuel, S.M.2    Marei, I.3    Ding, H.4    Triggle, C.R.5
  • 6
    • 79956331962 scopus 로고    scopus 로고
    • Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1
    • Back J.H., Rezvani H.R., Zhu Y.C., Guyonnet-Duperat V., Athar M., Ratner D., Kim A.L. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1. J. Biol. Chem. 2011, 286:19100-19108.
    • (2011) J. Biol. Chem. , vol.286 , pp. 19100-19108
    • Back, J.H.1    Rezvani, H.R.2    Zhu, Y.C.3    Guyonnet-Duperat, V.4    Athar, M.5    Ratner, D.6    Kim, A.L.7
  • 9
    • 84864708402 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5-mediated hyperphosphorylation of sirtuin-1 contributes to the development of endothelial senescence and atherosclerosis
    • Bai B., Liang Y., Xu C., Lee M.Y., Xu A., Wu D., Vanhoutte P.M., Wang Y. Cyclin-dependent kinase 5-mediated hyperphosphorylation of sirtuin-1 contributes to the development of endothelial senescence and atherosclerosis. Circulation 2012, 126:729-740.
    • (2012) Circulation , vol.126 , pp. 729-740
    • Bai, B.1    Liang, Y.2    Xu, C.3    Lee, M.Y.4    Xu, A.5    Wu, D.6    Vanhoutte, P.M.7    Wang, Y.8
  • 10
    • 84927946082 scopus 로고    scopus 로고
    • PGC-1alpha buffers ROS-mediated removal of mitochondria during myogenesis
    • Baldelli S., Aquilano K., Ciriolo M.R. PGC-1alpha buffers ROS-mediated removal of mitochondria during myogenesis. Cell Death Dis. 2014, 5:e1515.
    • (2014) Cell Death Dis. , vol.5 , pp. e1515
    • Baldelli, S.1    Aquilano, K.2    Ciriolo, M.R.3
  • 12
    • 84892539196 scopus 로고    scopus 로고
    • Do we age because we have mitochondria?
    • Bereiter-Hahn J. Do we age because we have mitochondria?. Protoplasma 2014, 251:3-23.
    • (2014) Protoplasma , vol.251 , pp. 3-23
    • Bereiter-Hahn, J.1
  • 13
    • 84937969345 scopus 로고    scopus 로고
    • Mitochondrial dynamics: orchestrating the journey to advanced age
    • Biala A.K., Dhingra R., Kirshenbaum L.A. Mitochondrial dynamics: orchestrating the journey to advanced age. J. Mol. Cell. Cardiol. 2015, 83:37-43.
    • (2015) J. Mol. Cell. Cardiol. , vol.83 , pp. 37-43
    • Biala, A.K.1    Dhingra, R.2    Kirshenbaum, L.A.3
  • 14
    • 84887020906 scopus 로고    scopus 로고
    • Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3
    • Brenmoehl J., Hoeflich A. Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3. Mitochondrion 2013, 13:755-761.
    • (2013) Mitochondrion , vol.13 , pp. 755-761
    • Brenmoehl, J.1    Hoeflich, A.2
  • 15
    • 78650048197 scopus 로고    scopus 로고
    • Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K IGF-1R signaling in human cancer cells
    • Byles Vanessa, Chmilewski L.K., Wang Joyce, Zhu Lijia, Forman Lora W., Faller Douglas V., Dai Yan Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K IGF-1R signaling in human cancer cells. Int. J. Biol. Sci. 2010, 6:599-612.
    • (2010) Int. J. Biol. Sci. , vol.6 , pp. 599-612
    • Byles, V.1    Chmilewski, L.K.2    Wang, J.3    Zhu, L.4    Forman, L.W.5    Faller, D.V.6    Dai, Y.7
  • 16
    • 77956180402 scopus 로고    scopus 로고
    • SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress
    • Caito S., Rajendrasozhan S., Cook S., Chung S., Yao H.W., Friedman A.E., Brookes P.S., Rahman I. SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress. FASEB J. 2010, 24:3145-3159.
    • (2010) FASEB J. , vol.24 , pp. 3145-3159
    • Caito, S.1    Rajendrasozhan, S.2    Cook, S.3    Chung, S.4    Yao, H.W.5    Friedman, A.E.6    Brookes, P.S.7    Rahman, I.8
  • 20
    • 84939979971 scopus 로고    scopus 로고
    • Mitochondria: biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations
    • Carelli V., Maresca A., Caporali L., Trifunov S., Zanna C., Rugolo M. Mitochondria: biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations. Int. J. Biochem. Cell Biol. 2015, 63:21-24.
    • (2015) Int. J. Biochem. Cell Biol. , vol.63 , pp. 21-24
    • Carelli, V.1    Maresca, A.2    Caporali, L.3    Trifunov, S.4    Zanna, C.5    Rugolo, M.6
  • 21
    • 27544434763 scopus 로고    scopus 로고
    • Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
    • Chen W.Y., Wang D.H., Yen R.C., Luo J., Gu W., Baylin S.B. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 2005, 123:437-448.
    • (2005) Cell , vol.123 , pp. 437-448
    • Chen, W.Y.1    Wang, D.H.2    Yen, R.C.3    Luo, J.4    Gu, W.5    Baylin, S.B.6
  • 22
    • 79954609893 scopus 로고    scopus 로고
    • Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner
    • Chen R., Dioum E.M., Hogg R.T., Gerard R.D., Garcia J.A. Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner. J. Biol. Chem. 2011, 286:13869-13878.
    • (2011) J. Biol. Chem. , vol.286 , pp. 13869-13878
    • Chen, R.1    Dioum, E.M.2    Hogg, R.T.3    Gerard, R.D.4    Garcia, J.A.5
  • 24
    • 84888131014 scopus 로고    scopus 로고
    • Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT
    • Choi S.E., Fu T., Seok S., Kim D.H., Yu E., Lee K.W., Kang Y., Li X., Kemper B., Kemper J.K. Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT. Aging Cell 2013, 12:1062-1072.
    • (2013) Aging Cell , vol.12 , pp. 1062-1072
    • Choi, S.E.1    Fu, T.2    Seok, S.3    Kim, D.H.4    Yu, E.5    Lee, K.W.6    Kang, Y.7    Li, X.8    Kemper, B.9    Kemper, J.K.10
  • 26
    • 84876230292 scopus 로고    scopus 로고
    • DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair
    • Dehennaut V., Loison I., Dubuissez M., Nassour J., Abbadie C., Leprince D. DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair. J. Biol. Chem. 2013, 288:10254-10264.
    • (2013) J. Biol. Chem. , vol.288 , pp. 10254-10264
    • Dehennaut, V.1    Loison, I.2    Dubuissez, M.3    Nassour, J.4    Abbadie, C.5    Leprince, D.6
  • 28
    • 84857293902 scopus 로고    scopus 로고
    • The role of PGC-1 coactivators in aging skeletal muscle and heart
    • Dillon L.M., Rebelo A.P., Moraes C.T. The role of PGC-1 coactivators in aging skeletal muscle and heart. IUBMB Life 2012, 64:231-241.
    • (2012) IUBMB Life , vol.64 , pp. 231-241
    • Dillon, L.M.1    Rebelo, A.P.2    Moraes, C.T.3
  • 30
    • 84857852626 scopus 로고    scopus 로고
    • Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition
    • Dixit D., Sharma V., Ghosh S., Mehta V.S., Sen E. Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition. Cell Death Dis. 2012, 9:e271.
    • (2012) Cell Death Dis. , vol.9 , pp. e271
    • Dixit, D.1    Sharma, V.2    Ghosh, S.3    Mehta, V.S.4    Sen, E.5
  • 31
    • 84855929223 scopus 로고    scopus 로고
    • SIRT1 protects against alpha-Synuclein aggregation by activating molecular chaperones
    • Donmez G., Arun A., Chung C.Y., McLean P.J., Lindquist S., Guarente L. SIRT1 protects against alpha-Synuclein aggregation by activating molecular chaperones. J. Neurosci. 2012, 32:124-132.
    • (2012) J. Neurosci. , vol.32 , pp. 124-132
    • Donmez, G.1    Arun, A.2    Chung, C.Y.3    McLean, P.J.4    Lindquist, S.5    Guarente, L.6
  • 34
    • 53649100104 scopus 로고    scopus 로고
    • JNK2-dependent regulation of SIRT1 protein stability
    • Ford J., Ahmed S., Allison S., Jiang M., Milner J. JNK2-dependent regulation of SIRT1 protein stability. Cell Cycle 2008, 7:3091-3097.
    • (2008) Cell Cycle , vol.7 , pp. 3091-3097
    • Ford, J.1    Ahmed, S.2    Allison, S.3    Jiang, M.4    Milner, J.5
  • 35
    • 0033887456 scopus 로고    scopus 로고
    • Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
    • Frye R.A. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem. Biophys. Res. Commun. 2000, 273:793-798.
    • (2000) Biochem. Biophys. Res. Commun. , vol.273 , pp. 793-798
    • Frye, R.A.1
  • 36
    • 34250758020 scopus 로고    scopus 로고
    • 2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD(+) depletion
    • 2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD(+) depletion. Cell. Physiol. Biochem. 2007, 20:45-54.
    • (2007) Cell. Physiol. Biochem. , vol.20 , pp. 45-54
    • Furukawa, A.1    Tada-Oikawa, S.2    Kawanishi, S.3    Oikawa, S.4
  • 38
    • 84918836448 scopus 로고    scopus 로고
    • The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction excessive superoxide production, and inflammation with aging in mice
    • Gano L.B., Donato A.J., Pasha H.M., Hearon C.M., Sindler A.L., Seals D.R. The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction excessive superoxide production, and inflammation with aging in mice. Am. J. Physiol. Heart Circ. Physiol. 2014, 307:H1754-H1763.
    • (2014) Am. J. Physiol. Heart Circ. Physiol. , vol.307 , pp. H1754-H1763
    • Gano, L.B.1    Donato, A.J.2    Pasha, H.M.3    Hearon, C.M.4    Sindler, A.L.5    Seals, D.R.6
  • 39
    • 84924245051 scopus 로고    scopus 로고
    • MicroRNA-204-5p-mediated regulation of SIRT1 contributes to the delay of epithelial cell cycle traversal in diabetic corneas
    • Gao J., Wang Y., Zhao X., Chen P., Xie L. MicroRNA-204-5p-mediated regulation of SIRT1 contributes to the delay of epithelial cell cycle traversal in diabetic corneas. Investig. Ophthalmol. Vis. Sci. 2015, 56:1493-1504.
    • (2015) Investig. Ophthalmol. Vis. Sci. , vol.56 , pp. 1493-1504
    • Gao, J.1    Wang, Y.2    Zhao, X.3    Chen, P.4    Xie, L.5
  • 40
    • 79959355078 scopus 로고    scopus 로고
    • Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity
    • Gao Z.G., Zhang J., Kheterpal I., Kennedy N., Davis R.J., Ye J.P. Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity. J. Biol. Chem. 2011, 286:22227-22234.
    • (2011) J. Biol. Chem. , vol.286 , pp. 22227-22234
    • Gao, Z.G.1    Zhang, J.2    Kheterpal, I.3    Kennedy, N.4    Davis, R.J.5    Ye, J.P.6
  • 42
    • 84906937543 scopus 로고    scopus 로고
    • Mitochondrial function and mitochondrial DNA maintenance with advancing age
    • Gaziev A.I., Abdullaev S., Podlutsky A. Mitochondrial function and mitochondrial DNA maintenance with advancing age. Biogerontology 2014, 15:417-438.
    • (2014) Biogerontology , vol.15 , pp. 417-438
    • Gaziev, A.I.1    Abdullaev, S.2    Podlutsky, A.3
  • 44
    • 84914145498 scopus 로고    scopus 로고
    • Age-dependent tissue expression patterns of Sirt1 in senescence-accelerated mice
    • Gong H., Pang J., Han Y.W., Dai Y., Dai D.P., Cai J.P., Zhang T.M. Age-dependent tissue expression patterns of Sirt1 in senescence-accelerated mice. Mol. Med. Rep. 2014, 10:3296-3302.
    • (2014) Mol. Med. Rep. , vol.10 , pp. 3296-3302
    • Gong, H.1    Pang, J.2    Han, Y.W.3    Dai, Y.4    Dai, D.P.5    Cai, J.P.6    Zhang, T.M.7
  • 45
  • 46
    • 77950584927 scopus 로고    scopus 로고
    • MicroRNA-125a represses cell growth by targeting HuR in breast cancer
    • Guo X., Wu Y., Hartley R.S. MicroRNA-125a represses cell growth by targeting HuR in breast cancer. RNA Biol. 2009, 6:575-583.
    • (2009) RNA Biol. , vol.6 , pp. 575-583
    • Guo, X.1    Wu, Y.2    Hartley, R.S.3
  • 47
    • 78649852533 scopus 로고    scopus 로고
    • SIRT1 is regulated by a PPAR-SIRT1 negative feedback loop associated with senescence
    • Han L., Zhou R., Niu J., McNutt M.A., Wang P., Tong T. SIRT1 is regulated by a PPAR-SIRT1 negative feedback loop associated with senescence. Nucleic Acids Res. 2010, 38:7458-7471.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 7458-7471
    • Han, L.1    Zhou, R.2    Niu, J.3    McNutt, M.A.4    Wang, P.5    Tong, T.6
  • 48
    • 34248379575 scopus 로고    scopus 로고
    • Ubiquitin and ubiquitin-like proteins in protein regulation
    • Herrmann J., Lerman L.O., Lerman A. Ubiquitin and ubiquitin-like proteins in protein regulation. Circ. Res. 2007, 100:1276-1291.
    • (2007) Circ. Res. , vol.100 , pp. 1276-1291
    • Herrmann, J.1    Lerman, L.O.2    Lerman, A.3
  • 49
    • 84893459319 scopus 로고    scopus 로고
    • SIRT1 in neurodevelopment and brain senescence
    • Herskovits A.Z., Guarente L. SIRT1 in neurodevelopment and brain senescence. Neuron 2014, 81:471-483.
    • (2014) Neuron , vol.81 , pp. 471-483
    • Herskovits, A.Z.1    Guarente, L.2
  • 52
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
    • Jager S., Handschin C., St-Pierre J., Spiegelman B.M. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:12017-12022.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 53
    • 84928895286 scopus 로고    scopus 로고
    • Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR-YY1-PGC1alpha pathway
    • Ji K., Zheng J., Lv J., Xu J., Ji X., Luo Y.B., Li W., Zhao Y., Yan C. Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR-YY1-PGC1alpha pathway. Free Radic. Biol. Med. 2015, 84:161-170.
    • (2015) Free Radic. Biol. Med. , vol.84 , pp. 161-170
    • Ji, K.1    Zheng, J.2    Lv, J.3    Xu, J.4    Ji, X.5    Luo, Y.B.6    Li, W.7    Zhao, Y.8    Yan, C.9
  • 55
    • 69949138641 scopus 로고    scopus 로고
    • CK2 Is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage
    • Kang H., Jung J.W., Kim M.K., Chung J.H. CK2 Is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage. PLoS One 2009, 4:e6611.
    • (2009) PLoS One , vol.4 , pp. e6611
    • Kang, H.1    Jung, J.W.2    Kim, M.K.3    Chung, J.H.4
  • 57
    • 84929162383 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species modulate innate immune response to influenza A virus in human nasal epithelium
    • Kim S., Kim M.J., Park D.Y., Chung H.J., Kim C.H., Yoon J.H., Kim H.J. Mitochondrial reactive oxygen species modulate innate immune response to influenza A virus in human nasal epithelium. Antivir. Res. 2015, 119:78-83.
    • (2015) Antivir. Res. , vol.119 , pp. 78-83
    • Kim, S.1    Kim, M.J.2    Park, D.Y.3    Chung, H.J.4    Kim, C.H.5    Yoon, J.H.6    Kim, H.J.7
  • 59
    • 84929320357 scopus 로고    scopus 로고
    • Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia
    • Kuo C.Y., Chiu Y.C., Lee A.Y., Hwang T.L. Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia. Mitochondrion 2015, 23:7-16.
    • (2015) Mitochondrion , vol.23 , pp. 7-16
    • Kuo, C.Y.1    Chiu, Y.C.2    Lee, A.Y.3    Hwang, T.L.4
  • 60
    • 84905221611 scopus 로고    scopus 로고
    • Mitochondrial quality control and age-associated arterial stiffening
    • LaRocca T.J., Hearon C.M., Henson G.D., Seals D.R. Mitochondrial quality control and age-associated arterial stiffening. Exp. Gerontol. 2014, 58:78-82.
    • (2014) Exp. Gerontol. , vol.58 , pp. 78-82
    • LaRocca, T.J.1    Hearon, C.M.2    Henson, G.D.3    Seals, D.R.4
  • 62
    • 79952742806 scopus 로고    scopus 로고
    • Increased expression of miR-34a and miR-93 in rat liver during aging: and their impact on the expression of Mgst1 and Sirt1
    • Li N., Muthusamy S., Liang R.Q., Sarojini H., Wang E. Increased expression of miR-34a and miR-93 in rat liver during aging: and their impact on the expression of Mgst1 and Sirt1. Mech. Ageing Dev. 2011, 132:75-85.
    • (2011) Mech. Ageing Dev. , vol.132 , pp. 75-85
    • Li, N.1    Muthusamy, S.2    Liang, R.Q.3    Sarojini, H.4    Wang, E.5
  • 63
    • 84883416378 scopus 로고    scopus 로고
    • Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor alpha (ERRalpha)
    • Li Y., He L., Zeng N., Sahu D., Cadenas E., Shearn C., Li W., Stiles B.L. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor alpha (ERRalpha). J. Biol. Chem. 2013, 288:25007-25024.
    • (2013) J. Biol. Chem. , vol.288 , pp. 25007-25024
    • Li, Y.1    He, L.2    Zeng, N.3    Sahu, D.4    Cadenas, E.5    Shearn, C.6    Li, W.7    Stiles, B.L.8
  • 64
    • 84941560081 scopus 로고    scopus 로고
    • Mitofusin-2-mediated tethering of mitochondria and endoplasmic reticulum promotes cell cycle arrest of vascular smooth muscle cells in G0/G1 phase
    • Li D., Li X., Guan Y., Guo X. Mitofusin-2-mediated tethering of mitochondria and endoplasmic reticulum promotes cell cycle arrest of vascular smooth muscle cells in G0/G1 phase. Acta Biochim. Biophys. Sin. (Shanghai) 2015, 47:441-450.
    • (2015) Acta Biochim. Biophys. Sin. (Shanghai) , vol.47 , pp. 441-450
    • Li, D.1    Li, X.2    Guan, Y.3    Guo, X.4
  • 65
    • 84938986138 scopus 로고    scopus 로고
    • Overexpression of SIRT1 induced by resveratrol and inhibitor of miR-204 suppresses activation and proliferation of microglia
    • Li L., Sun Q., Li Y., Yang Y., Yang Y., Chang T., Man M., Zheng L. Overexpression of SIRT1 induced by resveratrol and inhibitor of miR-204 suppresses activation and proliferation of microglia. J. Mol. Neurosci. 2015, 56:858-867.
    • (2015) J. Mol. Neurosci. , vol.56 , pp. 858-867
    • Li, L.1    Sun, Q.2    Li, Y.3    Yang, Y.4    Yang, Y.5    Chang, T.6    Man, M.7    Zheng, L.8
  • 66
    • 84906462901 scopus 로고    scopus 로고
    • Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3 K/Akt signaling to improve the effects of exercise in elderly rat hearts
    • Lin C.H., Lin C.C., Ting W.J., Pai P.Y., Kuo C.H., Ho T.J., Kuo W.W., Chang C.H., Huang C.Y., Lin W.T. Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3 K/Akt signaling to improve the effects of exercise in elderly rat hearts. Age (Dordr) 2014, 36:9705.
    • (2014) Age (Dordr) , vol.36 , pp. 9705
    • Lin, C.H.1    Lin, C.C.2    Ting, W.J.3    Pai, P.Y.4    Kuo, C.H.5    Ho, T.J.6    Kuo, W.W.7    Chang, C.H.8    Huang, C.Y.9    Lin, W.T.10
  • 67
    • 84933041134 scopus 로고    scopus 로고
    • Downregulation of dynamin-related protein 1 contributes to impaired autophagic flux and angiogenic function in senescent endothelial cells
    • Lin J.R., Shen W.L., Yan C., Gao P.J. Downregulation of dynamin-related protein 1 contributes to impaired autophagic flux and angiogenic function in senescent endothelial cells. Arterioscler. Thromb. Vasc. Biol. 2015, 35:1413-1422.
    • (2015) Arterioscler. Thromb. Vasc. Biol. , vol.35 , pp. 1413-1422
    • Lin, J.R.1    Shen, W.L.2    Yan, C.3    Gao, P.J.4
  • 68
    • 77951738458 scopus 로고    scopus 로고
    • A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms
    • Little J.P., Safdar A., Wilkin G.P., Tarnopolsky M.A., Gibala M.J. A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms. J. Physiol. 2010, 588:1011-1022.
    • (2010) J. Physiol. , vol.588 , pp. 1011-1022
    • Little, J.P.1    Safdar, A.2    Wilkin, G.P.3    Tarnopolsky, M.A.4    Gibala, M.J.5
  • 70
    • 84905457110 scopus 로고    scopus 로고
    • Ethanol suppresses PGC-1α expression by interfering with the cAMP-CREB pathway in neuronal cells
    • Liu Z., Liu Y., Gao R., Li H., Dunn T., Wu P., Smith R.G., Sarkar P.S., Fang X. Ethanol suppresses PGC-1α expression by interfering with the cAMP-CREB pathway in neuronal cells. PLoS One 2014, 9:e104247.
    • (2014) PLoS One , vol.9 , pp. e104247
    • Liu, Z.1    Liu, Y.2    Gao, R.3    Li, H.4    Dunn, T.5    Wu, P.6    Smith, R.G.7    Sarkar, P.S.8    Fang, X.9
  • 73
    • 84857873333 scopus 로고    scopus 로고
    • Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors
    • Lutzner N., Arce J.D., Rosl F. Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors. PLoS One 2012, 7:e32590.
    • (2012) PLoS One , vol.7 , pp. e32590
    • Lutzner, N.1    Arce, J.D.2    Rosl, F.3
  • 75
    • 84894143537 scopus 로고    scopus 로고
    • Partial reversal of skeletal muscle aging by restoration of normal NAD(+) levels
    • Mendelsohn A.R., Larrick J.W. Partial reversal of skeletal muscle aging by restoration of normal NAD(+) levels. Rejuvenation Res. 2014, 17:62-69.
    • (2014) Rejuvenation Res. , vol.17 , pp. 62-69
    • Mendelsohn, A.R.1    Larrick, J.W.2
  • 76
    • 84856554652 scopus 로고    scopus 로고
    • The role of SirT1 in muscle mitochondrial turnover
    • Menzies K.J., Hood D.A. The role of SirT1 in muscle mitochondrial turnover. Mitochondrion 2012, 12:5-13.
    • (2012) Mitochondrion , vol.12 , pp. 5-13
    • Menzies, K.J.1    Hood, D.A.2
  • 77
    • 26244436281 scopus 로고    scopus 로고
    • Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
    • Michishita E., Park J.Y., Burneskis J.M., Barrett J.C., Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Biol. Cell 2005, 16:4623-4635.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4623-4635
    • Michishita, E.1    Park, J.Y.2    Burneskis, J.M.3    Barrett, J.C.4    Horikawa, I.5
  • 78
    • 84923107636 scopus 로고    scopus 로고
    • Dysregulation of SIRT-1 in aging mice increases skeletal muscle fatigue by a PARP-1-dependent mechanism
    • Mohamed J.S., Wilson J.C., Myers M.J., Sisson K.J., Alway S.E. Dysregulation of SIRT-1 in aging mice increases skeletal muscle fatigue by a PARP-1-dependent mechanism. Aging (Albany NY) 2014, 6:820-834.
    • (2014) Aging (Albany NY) , vol.6 , pp. 820-834
    • Mohamed, J.S.1    Wilson, J.C.2    Myers, M.J.3    Sisson, K.J.4    Alway, S.E.5
  • 79
    • 34250340017 scopus 로고    scopus 로고
    • Glucose: palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line
    • Morgan D., Oliveira-Emilio H.R., Keane D., Hirata A.E., da Rocha M.S., Bordin S., Curi R., Newsholme P., Carpinelli A.R. Glucose: palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line. Diabetologia 2007, 50:359-369.
    • (2007) Diabetologia , vol.50 , pp. 359-369
    • Morgan, D.1    Oliveira-Emilio, H.R.2    Keane, D.3    Hirata, A.E.4    da Rocha, M.S.5    Bordin, S.6    Curi, R.7    Newsholme, P.8    Carpinelli, A.R.9
  • 80
    • 84874108083 scopus 로고    scopus 로고
    • Seven sirtuins for seven deadly diseases of aging
    • Morris B.J. Seven sirtuins for seven deadly diseases of aging. Free Radic. Biol. Med. 2013, 56:133-171.
    • (2013) Free Radic. Biol. Med. , vol.56 , pp. 133-171
    • Morris, B.J.1
  • 83
    • 10844236451 scopus 로고    scopus 로고
    • Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
    • Nemoto S., Fergusson M.M., Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004, 306:2105-2108.
    • (2004) Science , vol.306 , pp. 2105-2108
    • Nemoto, S.1    Fergusson, M.M.2    Finkel, T.3
  • 84
    • 0032988358 scopus 로고    scopus 로고
    • Glutamine metabolism by lymphocytes, macrophages, and neutrophils: its importance in health and disease
    • Newsholme F., Curi R., Curi T.C.P., Murphy C.J., Garcia C., de Melo M.P. Glutamine metabolism by lymphocytes, macrophages, and neutrophils: its importance in health and disease. J. Nutri. Biochem. 1999, 10:316-324.
    • (1999) J. Nutri. Biochem. , vol.10 , pp. 316-324
    • Newsholme, F.1    Curi, R.2    Curi, T.C.P.3    Murphy, C.J.4    Garcia, C.5    de Melo, M.P.6
  • 90
    • 84894141623 scopus 로고    scopus 로고
    • High glucose induced oxidative stress and apoptosis in cardiac microvascular endothelial cells are regulated by FoxO3a
    • Peng C., Ma J., Gao X., Tian P., Li W., Zhang L. High glucose induced oxidative stress and apoptosis in cardiac microvascular endothelial cells are regulated by FoxO3a. PLoS One 2013, 8:e79739.
    • (2013) PLoS One , vol.8 , pp. e79739
    • Peng, C.1    Ma, J.2    Gao, X.3    Tian, P.4    Li, W.5    Zhang, L.6
  • 91
    • 84868277570 scopus 로고    scopus 로고
    • Skeletal muscle mitochondria and aging: a review
    • Peterson C.M., Johannsen D.L., Ravussin E. Skeletal muscle mitochondria and aging: a review. J. Aging Res. 2012, 2012:194821.
    • (2012) J. Aging Res. , vol.2012 , pp. 194821
    • Peterson, C.M.1    Johannsen, D.L.2    Ravussin, E.3
  • 92
    • 84884149486 scopus 로고    scopus 로고
    • Aging and calorie restriction oppositely affect mitochondrial biogenesis through TFAM binding at both origins of mitochondrial DNA replication in rat liver
    • Picca A., Pesce V., Fracasso F., Joseph A.M., Leeuwenburgh C., Lezza A.M.S. Aging and calorie restriction oppositely affect mitochondrial biogenesis through TFAM binding at both origins of mitochondrial DNA replication in rat liver. PLoS One 2013, 8:e74644.
    • (2013) PLoS One , vol.8 , pp. e74644
    • Picca, A.1    Pesce, V.2    Fracasso, F.3    Joseph, A.M.4    Leeuwenburgh, C.5    Lezza, A.M.S.6
  • 93
    • 80051590849 scopus 로고    scopus 로고
    • Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice
    • Pramanik D., Campbell N.R., Karikari C., Chivukula R., Kent O.A., Mendell J.T., Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol. Cancer Ther. 2011, 10:1470-1480.
    • (2011) Mol. Cancer Ther. , vol.10 , pp. 1470-1480
    • Pramanik, D.1    Campbell, N.R.2    Karikari, C.3    Chivukula, R.4    Kent, O.A.5    Mendell, J.T.6    Maitra, A.7
  • 94
    • 63449112017 scopus 로고    scopus 로고
    • Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
    • Purushotham A., Schug T.T., Xu Q., Surapureddi S., Guo X.M., Li X.L. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab. 2009, 9:327-338.
    • (2009) Cell Metab. , vol.9 , pp. 327-338
    • Purushotham, A.1    Schug, T.T.2    Xu, Q.3    Surapureddi, S.4    Guo, X.M.5    Li, X.L.6
  • 95
    • 84918525766 scopus 로고    scopus 로고
    • Metformin prevents LYRM1-induced insulin resistance in 3T3-L1 adipocytes via a mitochondrial-dependent mechanism
    • Qin Z.Y., Zhang M., Dai Y.M., Wang Y.M., Zhu G.Z., Zhao Y.P., Ji C.B., Qiu J., Cao X.G., Guo X.R. Metformin prevents LYRM1-induced insulin resistance in 3T3-L1 adipocytes via a mitochondrial-dependent mechanism. Exp. Biol. Med. 2014, 239:1567-1574.
    • (2014) Exp. Biol. Med. , vol.239 , pp. 1567-1574
    • Qin, Z.Y.1    Zhang, M.2    Dai, Y.M.3    Wang, Y.M.4    Zhu, G.Z.5    Zhao, Y.P.6    Ji, C.B.7    Qiu, J.8    Cao, X.G.9    Guo, X.R.10
  • 96
    • 84923920035 scopus 로고    scopus 로고
    • Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid
    • Radogna F., Albertini M.C., De Nicola M., Diederich M., Bejarano I., Ghibelli L. Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid. Mitochondrion 2015, 21:113-121.
    • (2015) Mitochondrion , vol.21 , pp. 113-121
    • Radogna, F.1    Albertini, M.C.2    De Nicola, M.3    Diederich, M.4    Bejarano, I.5    Ghibelli, L.6
  • 97
    • 79952846843 scopus 로고    scopus 로고
    • Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic beta-islets
    • Ramachandran D., Roy U., Garg S., Ghosh S., Pathak S., Kolthur-Seetharam U. Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic beta-islets. FEBS J. 2011, 278:1167-1174.
    • (2011) FEBS J. , vol.278 , pp. 1167-1174
    • Ramachandran, D.1    Roy, U.2    Garg, S.3    Ghosh, S.4    Pathak, S.5    Kolthur-Seetharam, U.6
  • 98
    • 84961289051 scopus 로고    scopus 로고
    • Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases
    • Ramis M.R., Esteban S., Miralles A., Tan D.X., Reiter R.J. Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases. Mech. Ageing Dev. 2015, 146-148:28-41.
    • (2015) Mech. Ageing Dev. , pp. 28-41
    • Ramis, M.R.1    Esteban, S.2    Miralles, A.3    Tan, D.X.4    Reiter, R.J.5
  • 99
    • 84874228973 scopus 로고    scopus 로고
    • The ways and means that fine tune Sirt1 activity
    • Revollo J.R., Li X.L. The ways and means that fine tune Sirt1 activity. Trends Biochem. Sci. 2013, 38:160-167.
    • (2013) Trends Biochem. Sci. , vol.38 , pp. 160-167
    • Revollo, J.R.1    Li, X.L.2
  • 100
    • 37349110355 scopus 로고    scopus 로고
    • Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways
    • Rodgers J.T., Lerin C., Gerhart-Hines Z., Puigserver P. Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett. 2008, 582:46-53.
    • (2008) FEBS Lett. , vol.582 , pp. 46-53
    • Rodgers, J.T.1    Lerin, C.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 101
    • 84900481019 scopus 로고    scopus 로고
    • Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies
    • Rogers R.P., Rogina B. Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies. Aging (Albany NY) 2014, 6:335-350.
    • (2014) Aging (Albany NY) , vol.6 , pp. 335-350
    • Rogers, R.P.1    Rogina, B.2
  • 102
    • 84903723290 scopus 로고    scopus 로고
    • Bioenergetics and mitochondrial dysfunction in aging: recent insights for a therapeutical approach
    • Romano A.D., Greco E., Vendemiale G., Serviddio G. Bioenergetics and mitochondrial dysfunction in aging: recent insights for a therapeutical approach. Curr. Pharm. Des. 2014, 20:2978-2992.
    • (2014) Curr. Pharm. Des. , vol.20 , pp. 2978-2992
    • Romano, A.D.1    Greco, E.2    Vendemiale, G.3    Serviddio, G.4
  • 103
    • 0037123765 scopus 로고    scopus 로고
    • Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination
    • Rosenberg M.I., Parkhurst S.M. Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination. Cell 2002, 109:447-458.
    • (2002) Cell , vol.109 , pp. 447-458
    • Rosenberg, M.I.1    Parkhurst, S.M.2
  • 104
    • 84924653266 scopus 로고    scopus 로고
    • PPARó/á prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism
    • Salvadó Laia, Barroso Emma, Gómez-Foix Anna Maria, Palomer Xavier, Michalik Liliane, Wahli Walter, Vázquez-Carrera M. PPARó/á prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. Diabetologia 2014, 57:2126-2135.
    • (2014) Diabetologia , vol.57 , pp. 2126-2135
    • Salvadó, L.1    Barroso, E.2    Gómez-Foix, A.M.3    Palomer, X.4    Michalik, L.5    Wahli, W.6    Vázquez-Carrera, M.7
  • 106
    • 84883476818 scopus 로고    scopus 로고
    • Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
    • Satoh A., Brace C.S., Rensing N., Cliften P., Wozniak D.F., Herzog E.D., Yamada K.A., Imai S. Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab. 2013, 18:416-430.
    • (2013) Cell Metab. , vol.18 , pp. 416-430
    • Satoh, A.1    Brace, C.S.2    Rensing, N.3    Cliften, P.4    Wozniak, D.F.5    Herzog, E.D.6    Yamada, K.A.7    Imai, S.8
  • 107
    • 79957960940 scopus 로고    scopus 로고
    • Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
    • Scarpulla R.C. Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim. Biophys. Acta 2011, 1813:1269-1278.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1269-1278
    • Scarpulla, R.C.1
  • 109
    • 84864778051 scopus 로고    scopus 로고
    • Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-beta
    • Schonrock N., Humphreys D.T., Preiss T., Gotz J. Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-beta. J. Mol. Neurosci. 2012, 46:324-335.
    • (2012) J. Mol. Neurosci. , vol.46 , pp. 324-335
    • Schonrock, N.1    Humphreys, D.T.2    Preiss, T.3    Gotz, J.4
  • 111
    • 84902330009 scopus 로고    scopus 로고
    • Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart
    • Sin T.K., Yu A.P., Yung B.Y., Yip S.P., Chan L.W., Wong C.S., Ying M., Rudd J.A., Siu P.M. Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart. J. Physiol. 2014, 592:2535-2548.
    • (2014) J. Physiol. , vol.592 , pp. 2535-2548
    • Sin, T.K.1    Yu, A.P.2    Yung, B.Y.3    Yip, S.P.4    Chan, L.W.5    Wong, C.S.6    Ying, M.7    Rudd, J.A.8    Siu, P.M.9
  • 113
    • 34147208064 scopus 로고    scopus 로고
    • An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity
    • Stankovic-Valentin N., Deltour S., Seeler J., Pinte S., Vergoten G., Guerardel C., Dejean A., Leprince D. An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity. Mol. Cell. Biol. 2007, 27:1675-2661.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 1675-2661
    • Stankovic-Valentin, N.1    Deltour, S.2    Seeler, J.3    Pinte, S.4    Vergoten, G.5    Guerardel, C.6    Dejean, A.7    Leprince, D.8
  • 114
    • 68649119963 scopus 로고    scopus 로고
    • Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats
    • Sudheesh N.P., Ajith T.A., Janardhanan K.K., Krishnan C.V. Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats. Food Chem. Toxicol. 2009, 47:2124-2128.
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 2124-2128
    • Sudheesh, N.P.1    Ajith, T.A.2    Janardhanan, K.K.3    Krishnan, C.V.4
  • 115
    • 34250365395 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1
    • Tanno M., Sakamoto J., Miura T., Shimamoto K., Horio Y. Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1. J. Biol. Chem. 2007, 282:6823-6832.
    • (2007) J. Biol. Chem. , vol.282 , pp. 6823-6832
    • Tanno, M.1    Sakamoto, J.2    Miura, T.3    Shimamoto, K.4    Horio, Y.5
  • 126
    • 84938064270 scopus 로고    scopus 로고
    • Mitochondrial biogenesis is impaired in osteoarthritic chondrocytes but reversible via peroxisome proliferator-activated receptor-γ coactivator 1α
    • Wang Y., Zhao X., Lotz M., Terkeltaub R., Liu-Bryan R. Mitochondrial biogenesis is impaired in osteoarthritic chondrocytes but reversible via peroxisome proliferator-activated receptor-γ coactivator 1α. Arthritis Rheumatol. 2015, 67:2141-2153.
    • (2015) Arthritis Rheumatol. , vol.67 , pp. 2141-2153
    • Wang, Y.1    Zhao, X.2    Lotz, M.3    Terkeltaub, R.4    Liu-Bryan, R.5
  • 127
    • 84875246546 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis and PGC-1alpha under cellular stress
    • Wenz T. Regulation of mitochondrial biogenesis and PGC-1alpha under cellular stress. Mitochondrion 2013, 13:134-142.
    • (2013) Mitochondrion , vol.13 , pp. 134-142
    • Wenz, T.1
  • 128
    • 79953152333 scopus 로고    scopus 로고
    • FoxO1 mediates an autofeedback loop regulating SIRT1 expression
    • Xiong S., Salazar G., Patrushev N., Alexander R.W. FoxO1 mediates an autofeedback loop regulating SIRT1 expression. J. Biol. Chem. 2011, 286:5289-5299.
    • (2011) J. Biol. Chem. , vol.286 , pp. 5289-5299
    • Xiong, S.1    Salazar, G.2    Patrushev, N.3    Alexander, R.W.4
  • 130
    • 78549256935 scopus 로고    scopus 로고
    • Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma
    • Xu F., Zhang X.T., Lei Y.T., Liu X.W., Liu Z.Y., Tong T.J., Wang W.G. Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma. J. Cell. Biochem. 2010, 111:727-734.
    • (2010) J. Cell. Biochem. , vol.111 , pp. 727-734
    • Xu, F.1    Zhang, X.T.2    Lei, Y.T.3    Liu, X.W.4    Liu, Z.Y.5    Tong, T.J.6    Wang, W.G.7
  • 131
    • 84895538240 scopus 로고    scopus 로고
    • Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis
    • Xu Q., Xia P., Li X., Wang W., Liu Z., Gao X. Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis. PLoS One 2014, 9:e88243.
    • (2014) PLoS One , vol.9 , pp. e88243
    • Xu, Q.1    Xia, P.2    Li, X.3    Wang, W.4    Liu, Z.5    Gao, X.6
  • 133
    • 84867861519 scopus 로고    scopus 로고
    • Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
    • Yao H., Rahman I. Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence. Biochem. Pharmacol. 2012, 84:1332-1339.
    • (2012) Biochem. Pharmacol. , vol.84 , pp. 1332-1339
    • Yao, H.1    Rahman, I.2
  • 135
    • 84893421418 scopus 로고    scopus 로고
    • MicroRNA-217 promotes angiogenesis of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and FOXO3A
    • Zhang S.C., Liu L., Wang R.J., Tuo H.Z., Guo Y.J., Yi L., Wang D.X., Wang J.W. MicroRNA-217 promotes angiogenesis of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and FOXO3A. PLoS One 2013, 8:e83620.
    • (2013) PLoS One , vol.8 , pp. e83620
    • Zhang, S.C.1    Liu, L.2    Wang, R.J.3    Tuo, H.Z.4    Guo, Y.J.5    Yi, L.6    Wang, D.X.7    Wang, J.W.8
  • 136
    • 84888004362 scopus 로고    scopus 로고
    • MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS
    • Zhang S.C., Liu L., Wang R.J., Tuo H.Z., Guo Y.J., Yi L., Wang J.W., Wang D.X. MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS. Arch. Virol. 2013, 158:2443-2452.
    • (2013) Arch. Virol. , vol.158 , pp. 2443-2452
    • Zhang, S.C.1    Liu, L.2    Wang, R.J.3    Tuo, H.Z.4    Guo, Y.J.5    Yi, L.6    Wang, J.W.7    Wang, D.X.8
  • 137
    • 85027938704 scopus 로고    scopus 로고
    • MiR-132 inhibits expression of SIRT1 and induces pro-inflammatory processes of vascular endothelial inflammation through blockade of the SREBP-1c metabolic pathway
    • Zhang L.W., Huang D.S., Wang Q.S., Shen D., Wang Y.M., Chen B.Y., Zhang J.Q., Gai L.Y. MiR-132 inhibits expression of SIRT1 and induces pro-inflammatory processes of vascular endothelial inflammation through blockade of the SREBP-1c metabolic pathway. Cardiovasc. Drugs Ther. 2014, 28:303-311.
    • (2014) Cardiovasc. Drugs Ther. , vol.28 , pp. 303-311
    • Zhang, L.W.1    Huang, D.S.2    Wang, Q.S.3    Shen, D.4    Wang, Y.M.5    Chen, B.Y.6    Zhang, J.Q.7    Gai, L.Y.8
  • 138
    • 79958041304 scopus 로고    scopus 로고
    • Fine tuning our cellular factories: sirtuins in mitochondrial biology
    • Zhong L., Mostoslavsky R. Fine tuning our cellular factories: sirtuins in mitochondrial biology. Cell Metab. 2011, 13:621-626.
    • (2011) Cell Metab. , vol.13 , pp. 621-626
    • Zhong, L.1    Mostoslavsky, R.2
  • 139
    • 80052908737 scopus 로고    scopus 로고
    • MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1
    • Zhu H.Q., Yang Y.X., Wang Y.P., Li J.M., Schiller P.W., Peng T.Q. MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1. Cardiovasc. Res. 2011, 92:75-84.
    • (2011) Cardiovasc. Res. , vol.92 , pp. 75-84
    • Zhu, H.Q.1    Yang, Y.X.2    Wang, Y.P.3    Li, J.M.4    Schiller, P.W.5    Peng, T.Q.6
  • 140
    • 62049084424 scopus 로고    scopus 로고
    • Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2
    • Zschoernig B., Mahlknecht U. Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2. Biochem. Biophys. Res. Commun. 2009, 381:372-377.
    • (2009) Biochem. Biophys. Res. Commun. , vol.381 , pp. 372-377
    • Zschoernig, B.1    Mahlknecht, U.2


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