-
1
-
-
38649132337
-
Mitochondria-a nexus for aging, calorie restriction, and sirtuins?
-
Guarente L. Mitochondria-a nexus for aging, calorie restriction, and sirtuins? Cell. 2008; 132:171-176.
-
(2008)
Cell
, vol.132
, pp. 171-176
-
-
Guarente, L.1
-
2
-
-
32444437067
-
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
-
Lopez-Lluch G, Hunt N, Jones B, Zhu M, Jamieson H, Hilmer S, Cascajo MV, Allard J, Ingram DK, Navas P, and De Cabo R. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc Natl Acad Sci USA 2006; 103:1768-1773.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1768-1773
-
-
Lopez-Lluch, G.1
Hunt, N.2
Jones, B.3
Zhu, M.4
Jamieson, H.5
Hilmer, S.6
Cascajo, M.V.7
Allard, J.8
Ingram, D.K.9
Navas, P.10
De Cabo, R.11
-
3
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E, Moncada S, and Carruba MO. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science. 2005; 310:314-317.
-
(2005)
Science
, vol.310
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
Tedesco, L.6
Falcone, S.7
Valerio, A.8
Cantoni, O.9
Clementi, E.10
Moncada, S.11
Carruba, M.O.12
-
4
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
-
Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 2005; 39:359-407.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
5
-
-
43449097534
-
Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor
-
Choi NH, Kim JH, Yang DJ, Kim YS, and Yoo MA. Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor. Aging. 2008; Cell 7:318-334.
-
(2008)
Aging
, vol.CELL 7
, pp. 318-334
-
-
Choi, N.H.1
Kim, J.H.2
Yang, D.J.3
Kim, Y.S.4
Yoo, M.A.5
-
6
-
-
60549105369
-
Long-lived Indy induces reduced mitochondrial reactive oxygen species production and oxidative damage
-
Neretti N, Wang PY, Brodsky AS, Nyguyen HH, White KP, Rogina B, and Helfand SL. Long-lived Indy induces reduced mitochondrial reactive oxygen species production and oxidative damage. Proc Natl Acad Sci USA 2009; 106:2277-2282.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2277-2282
-
-
Neretti, N.1
Wang, P.Y.2
Brodsky, A.S.3
Nyguyen, H.H.4
White, K.P.5
Rogina, B.6
Helfand, S.L.7
-
7
-
-
79960969204
-
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice
-
Birkenfeld AL, Lee HY, Guebre-Egziabher F, Alves TC, Jurczak MJ, Jornayvaz FR, Zhang D, Hsiao JJ, Martin-Montalvo A, Fischer-Rosinsky A, Spranger J, Pfeiffer AF, Jordan J, et al. Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Cell Metab. 2011; 14:184-195.
-
(2011)
Cell Metab
, vol.14
, pp. 184-195
-
-
Birkenfeld, A.L.1
Lee, H.Y.2
Guebre-Egziabher, F.3
Alves, T.C.4
Jurczak, M.J.5
Jornayvaz, F.R.6
Zhang, D.7
Hsiao, J.J.8
Martin-Montalvo, A.9
Fischer-Rosinsky, A.10
Spranger, J.11
Pfeiffer, A.F.12
Jordan, J.13
-
8
-
-
0037458617
-
Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span
-
Fei YJ, Inoue K, and Ganapathy V. Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. J Biol Chem. 2003; 278:6136-6144.
-
(2003)
J Biol Chem
, vol.278
, pp. 6136-6144
-
-
Fei, Y.J.1
Inoue, K.2
Ganapathy, V.3
-
9
-
-
33745519687
-
The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates
-
Knauf F, Mohebbi N, Teichert C, Herold D, Rogina B, Helfand S, Gollash M, Luft FC, and Aronson PS. The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates. Biochem J. 2006; 387:25-29.
-
(2006)
Biochem J
, vol.387
, pp. 25-29
-
-
Knauf, F.1
Mohebbi, N.2
Teichert, C.3
Herold, D.4
Rogina, B.5
Helfand, S.6
Gollash, M.7
Luft, F.C.8
Aronson, P.S.9
-
10
-
-
0037195166
-
Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy
-
Knauf F, Rogina B, Jiang Z, Aronson PS, and Helfand SL. Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy. Proc Natl Acad Sci USA. 2002; 99:14315-14319.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14315-14319
-
-
Knauf, F.1
Rogina, B.2
Jiang, Z.3
Aronson, P.S.4
Helfand, S.L.5
-
11
-
-
1842844288
-
Relevance of NAC-2 and NA+-coupled citrate transporter, to lifespan, body size and fat content in Caenorhabditis elegans
-
Fei JY, Liu JC, Inoue K, Zhuang L, Miyake K, Miyauchi S, and Ganapathy V. Relevance of NAC-2 and NA+-coupled citrate transporter, to lifespan, body size and fat content in Caenorhabditis elegans. Biochem J. 2004; 379:191-198.
-
(2004)
Biochem J
, vol.379
, pp. 191-198
-
-
Fei, J.Y.1
Liu, J.C.2
Inoue, K.3
Zhuang, L.4
Miyake, K.5
Miyauchi, S.6
Ganapathy, V.7
-
12
-
-
84885879455
-
Indy mutations and Drosophila longevity
-
doi 10.3389/fgene.2013.00047
-
Rogina B, and Helfand SL. Indy mutations and Drosophila longevity. Front Genet. 2013; 4, doi: 10.3389/fgene.2013.00047.
-
(2013)
Front Genet
, vol.4
-
-
Rogina, B.1
Helfand, S.L.2
-
13
-
-
0034671596
-
Extended lifespan conferred by cotransporter gene mutations in Drosophila
-
Rogina B, Reenan RA, Nilsen S, and Helfand SL. Extended lifespan conferred by cotransporter gene mutations in Drosophila. Science. 2000; 290:2137-2140.
-
(2000)
Science
, vol.290
, pp. 2137-2140
-
-
Rogina, B.1
Reenan, R.A.2
Nilsen, S.3
Helfand, S.L.4
-
14
-
-
66649130906
-
Long-lived Indy and calorie restriction interact to extend life span
-
Wang PY, Neretti N, Whitaker R, Hosier S, Chang C, Lu D, Rogina B. and Helfand SL. Long-lived Indy and calorie restriction interact to extend life span. Proc Natl Acad Sci USA. 2009; 106:9262-9267.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9262-9267
-
-
Wang, P.Y.1
Neretti, N.2
Whitaker, R.3
Hosier, S.4
Chang, C.5
Lu, D.6
Rogina, B.7
Helfand, S.L.8
-
15
-
-
34248207609
-
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO
-
Gershman B, Puig O, Hang L, Peitzch RM, Tatar M and Garofalo RS. High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiol. Genomics. 2007; 29:24-34.
-
(2007)
Physiol. Genomics
, vol.29
, pp. 24-34
-
-
Gershman, B.1
Puig, O.2
Hang, L.3
Peitzch, R.M.4
Tatar, M.5
Garofalo, R.S.6
-
16
-
-
0037326196
-
Peroxisome proliferatoractivated receptor-gamma coactivator 1alpha (PGC-1alpha): transcriptional coactivator and metabolic regulator
-
Puigserver P, and Spiegelman BM. Peroxisome proliferatoractivated receptor-gamma coactivator 1alpha (PGC-1alpha): transcriptional coactivator and metabolic regulator. Endocr Rev. 2003; 24:78-90.
-
(2003)
Endocr Rev
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
17
-
-
80455143200
-
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
-
Rera M, Bahadorani S, Cho J, Koehler CL, Ulgherait M, Hur JH, Ansari WS, Lo TJr, Jones DL, and Walker DW. Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab. 2011; 14:623-634.
-
(2011)
Cell Metab
, vol.14
, pp. 623-634
-
-
Rera, M.1
Bahadorani, S.2
Cho, J.3
Koehler, C.L.4
Ulgherait, M.5
Hur, J.H.6
Ansari, W.S.7
Lo Jr., T.8
Jones, D.L.9
Walker, D.W.10
-
18
-
-
79551610653
-
Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
-
Hochmuth CE, Biteau B, Bohmann D, and Jasper H. Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Cell Stem Cell. 2011; 8:188-199.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 188-199
-
-
Hochmuth, C.E.1
Biteau, B.2
Bohmann, D.3
Jasper, H.4
-
19
-
-
78649519914
-
Metabolic regulation of stem cell behavior and implications for aging
-
Jasper H and Jones DL. Metabolic regulation of stem cell behavior and implications for aging. Cell Metab. 2010; 12:561-565.
-
(2010)
Cell Metab
, vol.12
, pp. 561-565
-
-
Jasper, H.1
Jones, D.L.2
-
20
-
-
31444452338
-
Evidence that ste cells reside in the adult Drosophila midgut epithelium
-
Micchelli CA and Perrimon N. Evidence that ste cells reside in the adult Drosophila midgut epithelium. Nature. 2006; 439:475-479.
-
(2006)
Nature
, vol.439
, pp. 475-479
-
-
Micchelli, C.A.1
Perrimon, N.2
-
21
-
-
31444444485
-
The adult Drosophila posterior midgut is maintained by pluripotent stem cells
-
Ohlstein B. Spradling A. The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature. 2006. 439:470-474.
-
(2006)
Nature
, vol.439
, pp. 470-474
-
-
Ohlstein, B.1
Spradling, A.2
-
22
-
-
33847168133
-
Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling
-
Ohlstein B, and Spradling A. Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling. Science. 2007; 315:988-992.
-
(2007)
Science
, vol.315
, pp. 988-992
-
-
Ohlstein, B.1
Spradling, A.2
-
24
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jager S, Handschin C, Zheng K, Lin J, Yang W, Simon DK, Bachoo R, and Spiegelman BM. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell. 2006; 127:397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
25
-
-
78449240115
-
Lifespan extension by preserving proliferative homeostasis in Drosophila
-
Biteau B, Karpac J, Supoyo S, DeGennaro M, Lehmann R, and Jasper H. Lifespan extension by preserving proliferative homeostasis in Drosophila. PLoS Genet. 2010; 6:e1001159.
-
(2010)
PLoS Genet
, vol.6
-
-
Biteau, B.1
Karpac, J.2
Supoyo, S.3
DeGennaro, M.4
Lehmann, R.5
Jasper, H.6
-
26
-
-
34249058364
-
Exploring strategies for protein trapping in Drosophila
-
Quinones-Coello AT, Petrella LN, Ayers K, Melillo A, Mazzalupo S, Hudson AM, Wang S, Castiblanco C, Buszczak M, Hoskins RA, and Cooley L. Exploring strategies for protein trapping in Drosophila. Genetics. 2007; 175:1089-1104.
-
(2007)
Genetics
, vol.175
, pp. 1089-1104
-
-
Quinones-Coello, A.T.1
Petrella, L.N.2
Ayers, K.3
Melillo, A.4
Mazzalupo, S.5
Hudson, A.M.6
Wang, S.7
Castiblanco, C.8
Buszczak, M.9
Hoskins, R.A.10
Cooley, L.11
-
27
-
-
0035962664
-
Histone H3 phosphorylation and cell division
-
Hans F, and Dimitrov FH. Histone H3 phosphorylation and cell division. Oncogene. 2001; 20:3021-3027.
-
(2001)
Oncogene
, vol.20
, pp. 3021-3027
-
-
Hans, F.1
Dimitrov, F.H.2
-
28
-
-
0027160708
-
Targeted gene expression as a mean of altering cell fates and generating dominant phenotypes
-
Brand AH, and Perrimon N. Targeted gene expression as a mean of altering cell fates and generating dominant phenotypes. Development. 1993; 118:401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
29
-
-
84876057074
-
Indy mutants: live long and prosper
-
doi: 10.3389/fgene.2012.00013
-
Frankel S, and Rogina B. Indy mutants: live long and prosper. Front Genet. 2012; 3:13 doi: 10.3389/fgene.2012.00013.
-
(2012)
Front Genet
, vol.3
, pp. 13
-
-
Frankel, S.1
Rogina, B.2
-
30
-
-
36048969072
-
No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects
-
Toivonen JM, Walker GA, Martinez-Diaz P, Bjedov I, Driege Y, Jacobs HT, Gems D, and Partridge L. No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. PLoS Genet. 2007; 3:e95.
-
(2007)
PLoS Genet
, vol.3
-
-
Toivonen, J.M.1
Walker, G.A.2
Martinez-Diaz, P.3
Bjedov, I.4
Driege, Y.5
Jacobs, H.T.6
Gems, D.7
Partridge, L.8
-
31
-
-
84855490988
-
The metabolome of induced pluripotent stem cells reveals metabolic changes occuring in somatic cell reprogramming
-
Panopoulos AD, Yanes O, Ruiz S, Kida YS, Diep D, Tautenhahn R, Herrerias A, Batchelder EM, Plongthongkum N, Lutz M, Berggren WT, Zhanf K, Evans RM, et al. The metabolome of induced pluripotent stem cells reveals metabolic changes occuring in somatic cell reprogramming. Cell Res. 2012; 22:168-177.
-
(2012)
Cell Res
, vol.22
, pp. 168-177
-
-
Panopoulos, A.D.1
Yanes, O.2
Ruiz, S.3
Kida, Y.S.4
Diep, D.5
Tautenhahn, R.6
Herrerias, A.7
Batchelder, E.M.8
Plongthongkum, N.9
Lutz, M.10
Berggren, W.T.11
Zhanf, K.12
Evans, R.M.13
-
32
-
-
84868351585
-
Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal
-
Zhang J, Nuebel E, Daley GQ, Koehler CM, and Teiteli MA. Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal. Cell Stem Cells. 2012; 11:589-595.
-
(2012)
Cell Stem Cells
, vol.11
, pp. 589-595
-
-
Zhang, J.1
Nuebel, E.2
Daley, G.Q.3
Koehler, C.M.4
Teiteli, M.A.5
-
33
-
-
80155123827
-
Altered modes of stem cell division drive adaptive intestinal growth
-
O'Brien LE, Soliman SS, Li X, and Bilder D. Altered modes of stem cell division drive adaptive intestinal growth. Cell 2011; 147:603-614.
-
(2011)
Cell
, vol.147
, pp. 603-614
-
-
O'Brien, L.E.1
Soliman, S.S.2
Li, X.3
Bilder, D.4
-
34
-
-
52949093944
-
JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut
-
Biteau B, Hochmuth CE, and Jasper H. JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut. Cell Stem Cell 2008; 3:442-455.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 442-455
-
-
Biteau, B.1
Hochmuth, C.E.2
Jasper, H.3
-
35
-
-
80755174406
-
Maintaining tissue homeostasis: dynamic control of somatic stem cell activity
-
Biteau B, Hochmuth CE, and Jasper H. Maintaining tissue homeostasis: dynamic control of somatic stem cell activity. Cell Stem Cell 2011; 9:402-411.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 402-411
-
-
Biteau, B.1
Hochmuth, C.E.2
Jasper, H.3
-
36
-
-
84863119126
-
Skeletal muscle transcriptional coactivator PGC-1a mediates mitochondrial, but not metabolic, changes during caloric restriction
-
Finley LWS, Lee J, Souza A, Desquiret-Dumas V, Bullock K, Rowe GC, Procaccio V, Clish CB., Arany Z, and Haigis M. Skeletal muscle transcriptional coactivator PGC-1a mediates mitochondrial, but not metabolic, changes during caloric restriction. Proc. Natl. Acad. Sci. USA. 2012; 109:2931-2936.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 2931-2936
-
-
Finley, L.W.S.1
Lee, J.2
Souza, A.3
Desquiret-Dumas, V.4
Bullock, K.5
Rowe, G.C.6
Procaccio, V.7
Clish, C.B.8
Arany, Z.9
Haigis, M.10
-
37
-
-
81755187019
-
Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway
-
Choi NH, Lucchetta E, and Ohlstein B. Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway. Proc. Natl. Aca. Sci. USA 2011; 108:18702-18707.
-
(2011)
Proc. Natl. Aca. Sci. USA
, vol.108
, pp. 18702-18707
-
-
Choi, N.H.1
Lucchetta, E.2
Ohlstein, B.3
-
38
-
-
0026750601
-
latheo, a new gene involved in associative learning and memory in Drosophila melanogaster identified from P element mutagenesis
-
Boynton S, and Tully T. latheo, a new gene involved in associative learning and memory in Drosophila melanogaster identified from P element mutagenesis. Genetics. 1992; 131:655-672.
-
(1992)
Genetics
, vol.131
, pp. 655-672
-
-
Boynton, S.1
Tully, T.2
-
39
-
-
34447530305
-
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
-
Dietzl G, Chen D, Schnorrer F, Su KC, Barinova Y, Fellner M, Gasser B, Kinsey K, Oppel S, Scheiblauer S, Couto A, Marra V, Keleman K, and Dickson BJ. A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature. 2007; 448:442-447.
-
(2007)
Nature
, vol.448
, pp. 442-447
-
-
Dietzl, G.1
Chen, D.2
Schnorrer, F.3
Su, K.C.4
Barinova, Y.5
Fellner, M.6
Gasser, B.7
Kinsey, K.8
Oppel, S.9
Scheiblauer, S.10
Couto, A.11
Marra, V.12
Keleman, K.13
Dickson, B.J.14
|