-
1
-
-
0028040875
-
The POZ domain: A conserved protein-protein interaction motif
-
V.J. Bardwell, and R. Treisman The POZ domain: a conserved protein-protein interaction motif Genes Dev. 8 1994 1664 1677
-
(1994)
Genes Dev.
, vol.8
, pp. 1664-1677
-
-
Bardwell, V.J.1
Treisman, R.2
-
2
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
A. Brunet, L.B. Sweeney, J.F. Sturgill, K.F. Chua, P.L. Greer, Y. Lin, H. Tran, S.E. Ross, R. Mostoslavsky, and H.Y. Cohen Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2004 2011 2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
3
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
S. Burma, B.P. Chen, M. Murphy, A. Kurimasa, and D.J. Chen ATM phosphorylates histone H2AX in response to DNA double-strand breaks J. Biol. Chem. 276 2001 42462 42467
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
4
-
-
0034639710
-
Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome
-
M.G. Carter, M.A. Johns, X. Zeng, L. Zhou, M.C. Zink, J.L. Mankowski, D.M. Donovan, and S.B. Baylin Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome Hum. Mol. Genet. 9 2000 413 419
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 413-419
-
-
Carter, M.G.1
Johns, M.A.2
Zeng, X.3
Zhou, L.4
Zink, M.C.5
Mankowski, J.L.6
Donovan, D.M.7
Baylin, S.B.8
-
5
-
-
0000346996
-
Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation
-
W.Y. Chen, and T.M. Townes Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation Proc. Natl. Acad. Sci. USA 97 2000 377 382
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 377-382
-
-
Chen, W.Y.1
Townes, T.M.2
-
6
-
-
5444259434
-
Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis
-
W.Y. Chen, T.K. Cooper, C.A. Zahnow, M. Overholtzer, Z. Zhao, M. Ladanyi, J.E. Karp, N. Gokgoz, J.S. Wunder, and I.L. Andrulis Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis Cancer Cell 6 2004 387 398
-
(2004)
Cancer Cell
, vol.6
, pp. 387-398
-
-
Chen, W.Y.1
Cooper, T.K.2
Zahnow, C.A.3
Overholtzer, M.4
Zhao, Z.5
Ladanyi, M.6
Karp, J.E.7
Gokgoz, N.8
Wunder, J.S.9
Andrulis, I.L.10
-
7
-
-
0037312934
-
Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors
-
W.Y. Chen, X. Zeng, M.G. Carter, C.N. Morrell, R.W. Chiu Yen, M. Esteller, D.N. Watkins, J.G. Herman, J.L. Mankowski, and S.B. Baylin Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors Nat. Genet. 33 2003 197 202
-
(2003)
Nat. Genet.
, vol.33
, pp. 197-202
-
-
Chen, W.Y.1
Zeng, X.2
Carter, M.G.3
Morrell, C.N.4
Chiu Yen, R.W.5
Esteller, M.6
Watkins, D.N.7
Herman, J.G.8
Mankowski, J.L.9
Baylin, S.B.10
-
8
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
H.Y. Cohen, C. Miller, K.J. Bitterman, N.R. Wall, B. Hekking, B. Kessler, K.T. Howitz, M. Gorospe, R. de Cabo, and D.A. Sinclair Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase Science 305 2004 390 392
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
9
-
-
0037444803
-
Histone deacetylases (HDACs): Characterization of the classical HDAC family
-
A.J. de Ruijter, A.H. van Gennip, H.N. Caron, S. Kemp, and A.B. van Kuilenburg Histone deacetylases (HDACs): characterization of the classical HDAC family Biochem. J. 370 2003 737 749
-
(2003)
Biochem. J.
, vol.370
, pp. 737-749
-
-
De Ruijter, A.J.1
Van Gennip, A.H.2
Caron, H.N.3
Kemp, S.4
Van Kuilenburg, A.B.5
-
10
-
-
0033593036
-
Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: The case of HIC-1 and gammaFBP-B
-
S. Deltour, C. Guerardel, and D. Leprince Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B Proc. Natl. Acad. Sci. USA 96 1999 14831 14836
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14831-14836
-
-
Deltour, S.1
Guerardel, C.2
Leprince, D.3
-
11
-
-
0036274143
-
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif
-
S. Deltour, S. Pinte, C. Guerardel, B. Wasylyk, and D. Leprince The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif Mol. Cell. Biol. 22 2002 4890 4901
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4890-4901
-
-
Deltour, S.1
Pinte, S.2
Guerardel, C.3
Wasylyk, B.4
Leprince, D.5
-
12
-
-
0030923519
-
Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein
-
P. Dhordain, O. Albagli, R.J. Lin, S. Ansieau, S. Quief, A. Leutz, J.P. Kerckaert, R.M. Evans, and D. Leprince Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein Proc. Natl. Acad. Sci. USA 94 1997 10762 10767
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10762-10767
-
-
Dhordain, P.1
Albagli, O.2
Lin, R.J.3
Ansieau, S.4
Quief, S.5
Leutz, A.6
Kerckaert, J.P.7
Evans, R.M.8
Leprince, D.9
-
13
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
E.R. Fearon, and B. Vogelstein A genetic model for colorectal tumorigenesis Cell 61 1990 759 767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
14
-
-
17144458786
-
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia
-
F. Grignani, S. De Matteis, C. Nervi, L. Tomassoni, V. Gelmetti, M. Cioce, M. Fanelli, M. Ruthardt, F.F. Ferrara, and I. Zamir Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia Nature 391 1998 815 818
-
(1998)
Nature
, vol.391
, pp. 815-818
-
-
Grignani, F.1
De Matteis, S.2
Nervi, C.3
Tomassoni, L.4
Gelmetti, V.5
Cioce, M.6
Fanelli, M.7
Ruthardt, M.8
Ferrara, F.F.9
Zamir, I.10
-
15
-
-
0345561556
-
Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome
-
C. Grimm, R. Sporle, T.E. Schmid, I.D. Adler, J. Adamski, K. Schughart, and J. Graw Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome Hum. Mol. Genet. 8 1999 697 710
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 697-710
-
-
Grimm, C.1
Sporle, R.2
Schmid, T.E.3
Adler, I.D.4
Adamski, J.5
Schughart, K.6
Graw, J.7
-
16
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
L. Guarente Sir2 links chromatin silencing, metabolism, and aging Genes Dev. 14 2000 1021 1026
-
(2000)
Genes Dev.
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
17
-
-
0035793579
-
Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53
-
C. Guerardel, S. Deltour, S. Pinte, D. Monte, A. Begue, A.K. Godwin, and D. Leprince Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53 J. Biol. Chem. 276 2001 3078 3089
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3078-3089
-
-
Guerardel, C.1
Deltour, S.2
Pinte, S.3
Monte, D.4
Begue, A.5
Godwin, A.K.6
Leprince, D.7
-
18
-
-
0028230596
-
Down-regulation of bcl-2 by p53 in breast cancer cells
-
S. Haldar, M. Negrini, M. Monne, S. Sabbioni, and C.M. Croce Down-regulation of bcl-2 by p53 in breast cancer cells Cancer Res. 54 1994 2095 2097
-
(1994)
Cancer Res.
, vol.54
, pp. 2095-2097
-
-
Haldar, S.1
Negrini, M.2
Monne, M.3
Sabbioni, S.4
Croce, C.M.5
-
19
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
T.C. He, S. Zhou, L.T. da Costa, J. Yu, K.W. Kinzler, and B. Vogelstein A simplified system for generating recombinant adenoviruses Proc. Natl. Acad. Sci. USA 95 1998 2509 2514
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
20
-
-
0037370309
-
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
-
M.T. Hemann, J.S. Fridman, J.T. Zilfou, E. Hernando, P.J. Paddison, C. Cordon-Cardo, G.J. Hannon, and S.W. Lowe An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo Nat. Genet. 33 2003 396 400
-
(2003)
Nat. Genet.
, vol.33
, pp. 396-400
-
-
Hemann, M.T.1
Fridman, J.S.2
Zilfou, J.T.3
Hernando, E.4
Paddison, P.J.5
Cordon-Cardo, C.6
Hannon, G.J.7
Lowe, S.W.8
-
21
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
K.T. Howitz, K.J. Bitterman, H.Y. Cohen, D.W. Lamming, S. Lavu, J.G. Wood, R.E. Zipkin, P. Chung, A. Kisielewski, and L.L. Zhang Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan Nature 425 2003 191 196
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
-
22
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
S. Imai, C.M. Armstrong, M. Kaeberlein, and L. Guarente Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase Nature 403 2000 795 800
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
23
-
-
0028001087
-
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
-
J.P. Issa, Y.L. Ottaviano, P. Celano, S.R. Hamilton, N.E. Davidson, and S.B. Baylin Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon Nat. Genet. 7 1994 536 540
-
(1994)
Nat. Genet.
, vol.7
, pp. 536-540
-
-
Issa, J.P.1
Ottaviano, Y.L.2
Celano, P.3
Hamilton, S.R.4
Davidson, N.E.5
Baylin, S.B.6
-
24
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
R.W. Johnstone, A.A. Ruefli, and S.W. Lowe Apoptosis: a link between cancer genetics and chemotherapy Cell 108 2002 153 164
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
25
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
P.A. Jones, and S.B. Baylin The fundamental role of epigenetic events in cancer Nat. Rev. Genet. 3 2002 415 428
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
26
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
M. Kaeberlein, M. McVey, and L. Guarente The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms Genes Dev. 13 1999 2570 2580
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
27
-
-
0032546017
-
Role of the histone deacetylase complex in acute promyelocytic leukaemia
-
R.J. Lin, L. Nagy, S. Inoue, W. Shao, W.H. Miller Jr., and R.M. Evans Role of the histone deacetylase complex in acute promyelocytic leukaemia Nature 391 1998 811 814
-
(1998)
Nature
, vol.391
, pp. 811-814
-
-
Lin, R.J.1
Nagy, L.2
Inoue, S.3
Shao, W.4
Miller Jr., W.H.5
Evans, R.M.6
-
28
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
S.J. Lin, P.A. Defossez, and L. Guarente Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae Science 289 2000 2126 2128
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
29
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
J. Luo, A.Y. Nikolaev, S. Imai, D. Chen, F. Su, A. Shiloh, L. Guarente, and W. Gu Negative control of p53 by Sir2alpha promotes cell survival under stress Cell 107 2001 137 148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
30
-
-
1442330508
-
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo
-
J. Luo, M. Li, Y. Tang, M. Laszkowska, R.G. Roeder, and W. Gu Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo Proc. Natl. Acad. Sci. USA 101 2004 2259 2264
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2259-2264
-
-
Luo, J.1
Li, M.2
Tang, Y.3
Laszkowska, M.4
Roeder, R.G.5
Gu, W.6
-
31
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
T. Miyashita, and J.C. Reed Tumor suppressor p53 is a direct transcriptional activator of the human bax gene Cell 80 1995 293 299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
32
-
-
0028292480
-
Identification of a p53-dependent negative response element in the bcl-2 gene
-
T. Miyashita, M. Harigai, M. Hanada, and J.C. Reed Identification of a p53-dependent negative response element in the bcl-2 gene Cancer Res. 54 1994 3131 3135
-
(1994)
Cancer Res.
, vol.54
, pp. 3131-3135
-
-
Miyashita, T.1
Harigai, M.2
Hanada, M.3
Reed, J.C.4
-
33
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
M.C. Motta, N. Divecha, M. Lemieux, C. Kamel, D. Chen, W. Gu, Y. Bultsma, M. McBurney, and L. Guarente Mammalian SIRT1 represses forkhead transcription factors Cell 116 2004 551 563
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
34
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
S. Nemoto, M.M. Fergusson, and T. Finkel Nutrient availability regulates SIRT1 through a forkhead-dependent pathway Science 306 2004 2105 2108
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
35
-
-
2942564591
-
Sirtuins: Sir2-related NAD-dependent protein deacetylases
-
B.J. North, and E. Verdin Sirtuins: Sir2-related NAD-dependent protein deacetylases Genome Biol. 5 2004 224
-
(2004)
Genome Biol.
, vol.5
, pp. 224
-
-
North, B.J.1
Verdin, E.2
-
36
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
E. Oda, R. Ohki, H. Murasawa, J. Nemoto, T. Shibue, T. Yamashita, T. Tokino, T. Taniguchi, and N. Tanaka Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis Science 288 2000 1053 1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
37
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
T.T. Paull, E.P. Rogakou, V. Yamazaki, C.U. Kirchgessner, M. Gellert, and W.M. Bonner A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage Curr. Biol. 10 2000 886 895
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
38
-
-
4644346198
-
The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: Definition of its consensus binding sequence and analysis of its DNA binding and repressive properties
-
S. Pinte, N. Stankovic-Valentin, S. Deltour, B.R. Rood, C. Guerardel, and D. Leprince The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties J. Biol. Chem. 279 2004 38313 38324
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 38313-38324
-
-
Pinte, S.1
Stankovic-Valentin, N.2
Deltour, S.3
Rood, B.R.4
Guerardel, C.5
Leprince, D.6
-
39
-
-
0346094379
-
Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain
-
J. Sakamoto, T. Miura, K. Shimamoto, and Y. Horio Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain FEBS Lett. 556 2004 281 286
-
(2004)
FEBS Lett.
, vol.556
, pp. 281-286
-
-
Sakamoto, J.1
Miura, T.2
Shimamoto, K.3
Horio, Y.4
-
40
-
-
0242322010
-
Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression
-
T. Senawong, V.J. Peterson, D. Avram, D.M. Shepherd, R.A. Frye, S. Minucci, and M. Leid Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression J. Biol. Chem. 278 2003 43041 43050
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43041-43050
-
-
Senawong, T.1
Peterson, V.J.2
Avram, D.3
Shepherd, D.M.4
Frye, R.A.5
Minucci, S.6
Leid, M.7
-
41
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
M. Serrano, H. Lee, L. Chin, C. Cordon-Cardo, D. Beach, and R.A. DePinho Role of the INK4a locus in tumor suppression and cell mortality Cell 85 1996 27 37
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
Depinho, R.A.6
-
42
-
-
2442564700
-
Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG
-
L.Q. Sun, D.W. Lee, Q. Zhang, W. Xiao, E.H. Raabe, A. Meeker, D. Miao, D.L. Huso, and R.J. Arceci Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG Genes Dev. 18 2004 1035 1046
-
(2004)
Genes Dev.
, vol.18
, pp. 1035-1046
-
-
Sun, L.Q.1
Lee, D.W.2
Zhang, Q.3
Xiao, W.4
Raabe, E.H.5
Meeker, A.6
Miao, D.7
Huso, D.L.8
Arceci, R.J.9
-
43
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
H.A. Tissenbaum, and L. Guarente Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 410 2001 227 230
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
44
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
M. Toyota, N. Ahuja, M. Ohe-Toyota, J.G. Herman, S.B. Baylin, and J.P. Issa CpG island methylator phenotype in colorectal cancer Proc. Natl. Acad. Sci. USA 96 1999 8681 8686
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
Herman, J.G.4
Baylin, S.B.5
Issa, J.P.6
-
45
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
A. Vaquero, M. Scher, D. Lee, H. Erdjument-Bromage, P. Tempst, and D. Reinberg Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin Mol. Cell 16 2004 93 105
-
(2004)
Mol. Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
46
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
H. Vaziri, S.K. Dessain, E. Ng Eaton, S.I. Imai, R.A. Frye, T.K. Pandita, L. Guarente, and R.A. Weinberg hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase Cell 107 2001 149 159
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
47
-
-
0029014425
-
P53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3
-
M.M. Wales, M.A. Biel, W. el Deiry, B.D. Nelkin, J.P. Issa, W.K. Cavenee, S.J. Kuerbitz, and S.B. Baylin p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3 Nat. Med. 1 1995 570 577
-
(1995)
Nat. Med.
, vol.1
, pp. 570-577
-
-
Wales, M.M.1
Biel, M.A.2
El Deiry, W.3
Nelkin, B.D.4
Issa, J.P.5
Cavenee, W.K.6
Kuerbitz, S.J.7
Baylin, S.B.8
-
49
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
J.G. Wood, B. Rogina, S. Lavu, K. Howitz, S.L. Helfand, M. Tatar, and D. Sinclair Sirtuin activators mimic caloric restriction and delay ageing in metazoans Nature 430 2004 686 689
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.7
-
50
-
-
0025822948
-
Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site
-
W.E. Wright, M. Binder, and W. Funk Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site Mol. Cell. Biol. 11 1991 4104 4110
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 4104-4110
-
-
Wright, W.E.1
Binder, M.2
Funk, W.3
-
51
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
J. Yu, L. Zhang, P.M. Hwang, K.W. Kinzler, and B. Vogelstein PUMA induces the rapid apoptosis of colorectal cancer cells Mol. Cell 7 2001 673 682
-
(2001)
Mol. Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
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