Downregulation of Dynamin-Related Protein 1 Contributes to Impaired Autophagic Flux and Angiogenic Function in Senescent Endothelial Cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 35, Issue 6, 2015, Pages 1413-1422

  Lin, Jing Rong ^a   Shen, Wei Li ^a   Yan, Chen ^a   Gao, Ping Jin ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

aging; autophagy; endothelial dysfunction; mitochondria; reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CELL PROTEIN; DYNAMIN; DYNAMIN RELATED PROTEIN 1; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 6; LIGHT CHAIN 3 PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN P16; PROTEIN P21; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; DNM1L PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL PROTEIN;

AGED; ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; BIOACCUMULATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; MICROVASCULATURE; MITOCHONDRIAL DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENESCENCE; THORACIC AORTA; VASCULAR RING; ANIMAL; CELL AGING; CYTOLOGY; METABOLISM; MUSCLE MITOCHONDRION; PHYSIOLOGY; UMBILICUS; VASCULAR SMOOTH MUSCLE; VASCULARIZATION; VEIN; WISTAR KYOTO RAT;

ANIMALS; AUTOPHAGY; CELL AGING; DOWN-REGULATION; ENDOTHELIAL CELLS; GTP PHOSPHOHYDROLASES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE, SMOOTH, VASCULAR; RATS, INBRED WKY; REACTIVE OXYGEN SPECIES; UMBILICUS; VEINS;

EID: 84933041134     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.305706     Document Type: Article

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