메뉴 건너뛰기




Volumn 29, Issue 5, 2015, Pages 1725-1738

AMPKα is critical for enhancing skeletal muscle fatty acid utilization during in vivo exercise in mice

Author keywords

CD36; Fat oxidation; Glucose uptake; Physical activity; TBC1D1

Indexed keywords

ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE ALPHA; ADENYLATE KINASE; CLUSTER OF DIFFERENTIATION 36; FATTY ACID; FATTY ACID TRANSPORTER; MUSCLE PROTEIN; PLASMA MEMBRANE FATTY ACID BINDING PROTEIN; TBC1D1 PROTEIN; UNCLASSIFIED DRUG; AMPK ALPHA1 SUBUNIT, MOUSE; AMPK ALPHA2 SUBUNIT, MOUSE; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

EID: 84930606183     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-266650     Document Type: Article
Times cited : (68)

References (49)
  • 2
    • 84895539245 scopus 로고    scopus 로고
    • Mitochondrial function in metabolic health: A genetic and environmental tug of war
    • Stephenson, E. J., and Hawley, J. A. (2014) Mitochondrial function in metabolic health: a genetic and environmental tug of war. Biochim. Biophys. Acta 1840, 1285-1294
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 1285-1294
    • Stephenson, E.J.1    Hawley, J.A.2
  • 3
    • 70349921265 scopus 로고    scopus 로고
    • A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle
    • Treebak, J. T., Birk, J. B., Hansen, B. F., Olsen, G. S., and Wojtaszewski, J. F. (2009) A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle. Am. J. Physiol. Cell Physiol. 297, C1041-C1052
    • (2009) Am. J. Physiol. Cell Physiol. , vol.297 , pp. C1041-C1052
    • Treebak, J.T.1    Birk, J.B.2    Hansen, B.F.3    Olsen, G.S.4    Wojtaszewski, J.F.5
  • 4
    • 84858782079 scopus 로고    scopus 로고
    • AMPK: A nutrient and energy sensor that maintains energy homeostasis
    • Hardie, D. G., Ross, F. A., and Hawley, S. A. (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13, 251-262
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 5
    • 0020624753 scopus 로고
    • Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat
    • McGarry, J. D., Mills, S. E., Long, C. S., and Foster, D. W. (1983) Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat. Biochem. J. 214, 21-28
    • (1983) Biochem. J. , vol.214 , pp. 21-28
    • McGarry, J.D.1    Mills, S.E.2    Long, C.S.3    Foster, D.W.4
  • 6
    • 0029978799 scopus 로고    scopus 로고
    • Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
    • Winder, W. W., and Hardie, D. G. (1996) Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am. J. Physiol. 270, E299-E304
    • (1996) Am. J. Physiol. , vol.270 , pp. E299-E304
    • Winder, W.W.1    Hardie, D.G.2
  • 7
    • 0024998320 scopus 로고
    • Time course of exercise-induced decline in malonyl-CoA in different muscle types
    • Winder, W. W., Arogyasami, J., Elayan, I. M., and Cartmill, D. (1990) Time course of exercise-induced decline in malonyl-CoA in different muscle types. Am. J. Physiol. 259, E266-E271
    • (1990) Am. J. Physiol. , vol.259 , pp. E266-E271
    • Winder, W.W.1    Arogyasami, J.2    Elayan, I.M.3    Cartmill, D.4
  • 8
    • 0037677773 scopus 로고    scopus 로고
    • Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling
    • Luiken, J. J. F. P., Coort, S. L. M., Willems, J., Coumans, W. A., Bonen, A., Van Der Vusse, G. J., and Glatz, J. F. C. (2003) Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling. Diabetes 52, 1627-1634
    • (2003) Diabetes , vol.52 , pp. 1627-1634
    • Luiken, J.J.F.P.1    Coort, S.L.M.2    Willems, J.3    Coumans, W.A.4    Bonen, A.5    Van Der Vusse, G.J.6    Glatz, J.F.C.7
  • 9
    • 17644379557 scopus 로고    scopus 로고
    • The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR
    • Chabowski, A., Coort, S. L. M., Calles-Escandon, J., Tandon, N. N., Glatz, J. F. C., Luiken, J. J. F. P., and Bonen, A. (2005) The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR. FEBS Lett. 579, 2428-2432
    • (2005) FEBS Lett. , vol.579 , pp. 2428-2432
    • Chabowski, A.1    Coort, S.L.M.2    Calles-Escandon, J.3    Tandon, N.N.4    Glatz, J.F.C.5    Luiken, J.J.F.P.6    Bonen, A.7
  • 10
    • 0032998539 scopus 로고    scopus 로고
    • Proteinmediated palmitate uptake and expression of fatty acid transport proteins in heart giant vesicles
    • Luiken, J. J. F. P., Turcotte, L. P., and Bonen, A. (1999) Proteinmediated palmitate uptake and expression of fatty acid transport proteins in heart giant vesicles. J. Lipid Res. 40, 1007-1016
    • (1999) J. Lipid Res. , vol.40 , pp. 1007-1016
    • Luiken, J.J.F.P.1    Turcotte, L.P.2    Bonen, A.3
  • 11
    • 36749103888 scopus 로고    scopus 로고
    • Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane
    • Chabowski, A., Górski, J., Luiken, J. J., Glatz, J. F., and Bonen, A. (2007) Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane. Prostaglandins Leukot. Essent. Fatty Acids 77, 345-353
    • (2007) Prostaglandins Leukot. Essent. Fatty Acids , vol.77 , pp. 345-353
    • Chabowski, A.1    Górski, J.2    Luiken, J.J.3    Glatz, J.F.4    Bonen, A.5
  • 17
    • 84880181066 scopus 로고    scopus 로고
    • Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: Changes occurring in the diaphragm
    • Miura, S., Kai, Y., Tadaishi, M., Tokutake, Y., Sakamoto, K, Bruce, C. R., Febbraio, M. A., Kita, K, Chohnan, S., and Ezaki, O. (2013) Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. Am. J. Physiol. Endocrinol. Metab. 305, E213-E229
    • (2013) Am. J. Physiol. Endocrinol. Metab. , vol.305 , pp. E213-E229
    • Miura, S.1    Kai, Y.2    Tadaishi, M.3    Tokutake, Y.4    Sakamoto, K.5    Bruce, C.R.6    Febbraio, M.A.7    Kita, K.8    Chohnan, S.9    Ezaki, O.10
  • 22
    • 0345832116 scopus 로고    scopus 로고
    • Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside but not contraction-induced glucose uptake in skeletal muscle
    • Jørgensen, S. B., Viollet, B., Andreelli, F., Frøsig, C., Birk, J. B., Schjerling, P., Vaulont, S., Richter, E. A, and Wojtaszewski, J. F. (2004) Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside but not contraction-induced glucose uptake in skeletal muscle. J. Biol. Chem. 279, 1070-1079
    • (2004) J. Biol. Chem. , vol.279 , pp. 1070-1079
    • Jørgensen, S.B.1    Viollet, B.2    Andreelli, F.3    Frøsig, C.4    Birk, J.B.5    Schjerling, P.6    Vaulont, S.7    Richter, E.A.8    Wojtaszewski, J.F.9
  • 24
    • 0001960537 scopus 로고
    • Determination of blood sugar
    • Somogyi, M. (1945) Determination of blood sugar. J. Biol. Chem. 160, 69-73
    • (1945) J. Biol. Chem. , vol.160 , pp. 69-73
    • Somogyi, M.1
  • 25
    • 0022036226 scopus 로고
    • Dose-response curves for in vivo insulin sensitivity in individual tissues in rats
    • Kraegen, E. W., James, D. E., Jenkins, A. B., and Chisholm, D. J. (1985) Dose-response curves for in vivo insulin sensitivity in individual tissues in rats. Am. J. Physiol. 248, E353-E362
    • (1985) Am. J. Physiol. , vol.248 , pp. E353-E362
    • Kraegen, E.W.1    James, D.E.2    Jenkins, A.B.3    Chisholm, D.J.4
  • 26
    • 0346157023 scopus 로고    scopus 로고
    • Distributed control of glucose uptake by working muscles of conscious mice: Roles of transport and phosphorylation
    • Fueger, P. T., Bracy, D. P., Malabanan, C. M., Pencek, R. R, and Wasserman, D. H. (2004) Distributed control of glucose uptake by working muscles of conscious mice: roles of transport and phosphorylation. Am. J. Physiol. Endocrinol. Metab. 286, E77-E84
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.286 , pp. E77-E84
    • Fueger, P.T.1    Bracy, D.P.2    Malabanan, C.M.3    Pencek, R.R.4    Wasserman, D.H.5
  • 27
    • 77953768762 scopus 로고    scopus 로고
    • AMPKalpha1 deletion shortens erythrocyte life span in mice: Role of oxidative stress
    • Wang, S., Dale, G. L., Song, P., Viollet, B., and Zou, M. H. (2010) AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress. J. Biol. Chem. 285, 19976-19985
    • (2010) J. Biol. Chem. , vol.285 , pp. 19976-19985
    • Wang, S.1    Dale, G.L.2    Song, P.3    Viollet, B.4    Zou, M.H.5
  • 28
    • 2142640818 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages
    • Jhun, B. S., Jin, Q., Oh, Y T., Kim, S. S., Kong, Y, Cho, Y H., Ha, J., Baik, H. H., and Kang, I. (2004) 5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages. Biochem. Biophys. Res. Commun. 318, 372-380
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 372-380
    • Jhun, B.S.1    Jin, Q.2    Oh, Y.T.3    Kim, S.S.4    Kong, Y.5    Cho, Y.H.6    Ha, J.7    Baik, H.H.8    Kang, I.9
  • 29
    • 58849115949 scopus 로고    scopus 로고
    • Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype. J
    • Sag, D., Carling, D., Stout, R. D., and Suttles, J. (2008) Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype. J. Immunol. 181, 8633-8641
    • (2008) Immunol. , vol.181 , pp. 8633-8641
    • Sag, D.1    Carling, D.2    Stout, R.D.3    Suttles, J.4
  • 30
    • 0028334748 scopus 로고
    • Balance of carbohydrate and lipid utilization during exercise: The "crossover" concept
    • Brooks, G. A., and Mercier, J. (1994) Balance of carbohydrate and lipid utilization during exercise: the "crossover" concept. J. Appl. Physiol. 76, 2253-2261
    • (1994) J. Appl. Physiol. , vol.76 , pp. 2253-2261
    • Brooks, G.A.1    Mercier, J.2
  • 33
    • 74949084316 scopus 로고    scopus 로고
    • Membrane fatty acid transporters as regulators of lipid metabolism: Implications for metabolic disease
    • Glatz, J. F. C., Luiken, J. J. F. P., Andbonen, A. (2010) Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. Physiol. Rev. 90, 367-417
    • (2010) Physiol. Rev. , vol.90 , pp. 367-417
    • Glatz, J.F.C.1    Luiken, J.J.F.P.2    Andbonen, A.3
  • 34
    • 0034693232 scopus 로고    scopus 로고
    • Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice
    • Coburn, C. T., Knapp, F. F., Jr., Febbraio, M., Beets, A. L., Silverstein, R L., and Abumrad, N. A. (2000) Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J. Biol. Chem. 275, 32523-32529
    • (2000) J. Biol. Chem. , vol.275 , pp. 32523-32529
    • Coburn, C.T.1    Knapp, F.F.2    Febbraio, M.3    Beets, A.L.4    Silverstein, R.L.5    Abumrad, N.A.6
  • 35
    • 34447555830 scopus 로고    scopus 로고
    • A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism
    • Bonen, A., Han, X. X., Habets, D. D. J., Febbraio, M., Glatz, J. F. C., and Luiken, J. J. F. P. (2007) A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism. Am. J. Physiol. Endocrinol. Metab. 292, E1740-E1749
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.292 , pp. E1740-E1749
    • Bonen, A.1    Han, X.X.2    Habets, D.D.J.3    Febbraio, M.4    Glatz, J.F.C.5    Luiken, J.J.F.P.6
  • 36
    • 1842457594 scopus 로고    scopus 로고
    • Overexpression of membrane-associated fatty acid binding protein (FABPpm) in vivo increases fatty acid sarcolemmal transport and metabolism
    • Clarke, D. C., Miskovic, D., Han, X. X., Calles-Escandon, J., Glatz, J. F. C., Luiken, J. J. F. P., Heikkila, J. J., and Bonen, A. (2004) Overexpression of membrane-associated fatty acid binding protein (FABPpm) in vivo increases fatty acid sarcolemmal transport and metabolism. Physiol. Genomics 17, 31-37
    • (2004) Physiol. Genomics , vol.17 , pp. 31-37
    • Clarke, D.C.1    Miskovic, D.2    Han, X.X.3    Calles-Escandon, J.4    Glatz, J.F.C.5    Luiken, J.J.F.P.6    Heikkila, J.J.7    Bonen, A.8
  • 39
    • 69049099087 scopus 로고    scopus 로고
    • Genetic disruption of AMPK signaling abolishes both contractionand insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle
    • Pehmøller, C., Treebak, J. T., Birk, J. B., Chen, S., Mackintosh, C., Hardie, D. G., Richter, E. A., and Wojtaszewski, J. F. (2009) Genetic disruption of AMPK signaling abolishes both contractionand insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 297, E665-E675
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297 , pp. E665-E675
    • Pehmøller, C.1    Treebak, J.T.2    Birk, J.B.3    Chen, S.4    Mackintosh, C.5    Hardie, D.G.6    Richter, E.A.7    Wojtaszewski, J.F.8
  • 42
    • 84884692647 scopus 로고    scopus 로고
    • Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle
    • Dokas, J., Chadt, A., Nolden, T., Himmelbauer, H., Zierath, J. R., Joost, H. G., and Al-Hasani, H. (2013) Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle. Endocrinology 154, 3502-3514
    • (2013) Endocrinology , vol.154 , pp. 3502-3514
    • Dokas, J.1    Chadt, A.2    Nolden, T.3    Himmelbauer, H.4    Zierath, J.R.5    Joost, H.G.6    Al-Hasani, H.7
  • 44
    • 84859387660 scopus 로고    scopus 로고
    • Insulin and AMPK regulate FA translocase/CD36 plasma membrane recruitment in cardiomyocytes via Rab GAP AS160 and Rab8a Rab GTPase
    • Samovski, D., Su, X., Xu, Y., Abumrad, N. A., and Stahl, P. D. (2012) Insulin and AMPK regulate FA translocase/CD36 plasma membrane recruitment in cardiomyocytes via Rab GAP AS160 and Rab8a Rab GTPase. J. Lipid Res. 53, 709-717
    • (2012) J. Lipid Res. , vol.53 , pp. 709-717
    • Samovski, D.1    Su, X.2    Xu, Y.3    Abumrad, N.A.4    Stahl, P.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.