Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice

Cell Metabolism

Volumn 2, Issue 2, 2005, Pages 105-117

  Moynihan, Kathryn A ^a   Grimm, Andrew A ^a   Plueger, Marie M ^a   Bernal Mizrachi, Ernesto ^a   Ford, Eric ^a   Cras Méneur, Corentin ^a   Permutt, M Alan ^a   Imai, Shin Ichiro ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; INSULIN; POTASSIUM CHLORIDE; SILENT INFORMATION REGULATOR PROTEIN 2; UNCOUPLING PROTEIN 2; GLUCAGON; SIRT1 PROTEIN, MOUSE; SIRTUIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MICROARRAY ANALYSIS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS PERFUSION; PHENOTYPIC VARIATION; PRIORITY JOURNAL; RAT; TRANSGENIC MOUSE; ANIMAL; CELL CULTURE; CYTOLOGY; DNA MICROARRAY; FEMALE; GENE DOSAGE; GENE EXPRESSION PROFILING; GENETICS; GLUCOSE TOLERANCE TEST; METABOLISM; PANCREAS ISLET; PHYSIOLOGY; SECRETION;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

ANIMALS; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; FEMALE; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLUCAGON; GLUCOSE; GLUCOSE TOLERANCE TEST; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIRTUINS;

EID: 25144454432     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2005.07.001     Document Type: Article

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