-
1
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
DOI 10.1126/science.1099196
-
Cohen, H. Y, Miller, C, Bitterman, K.J., Wall, N. R, Hekking, B., Kessler, B., Howitz, K. T., Gorospe, M., de Cabo, R, and Sinclair, D. A. (2004) Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305, 390-392 (Pubitemid 38938153)
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
2
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
DOI 10.1101/gad.13.19.2570
-
Kaeberlein, M., McVey, M., and Guarente, L. (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13, 2570-2580 (Pubitemid 29489648)
-
(1999)
Genes and Development
, vol.13
, Issue.19
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
3
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
DOI 10.1038/35065638
-
Tissenbaum, H. A., and Guarente, L. (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410, 227-230 (Pubitemid 32216597)
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
5
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
Wang, R. H., Sengupta, K, Li, C, and Kim., H. S., Cao, L., Xiao, C, Kim, S., Xu, X., Zheng, Y., Chilton, B., Jia, R., Zheng, Z. M., Appella, E., Wang, X. W., Ried, T., and Deng, C. X. (2008) Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14, 312-323
-
(2008)
Cancer Cell
, vol.14
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
Kim, H.S.4
Cao, L.5
Xiao, C.6
Kim, S.7
Xu, X.8
Zheng, Y.9
Chilton, B.10
Jia, R.11
Zheng, Z.M.12
Appella, E.13
Wang, X.W.14
Ried, T.15
Deng, C.X.16
-
6
-
-
68949113934
-
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
-
Boily, G., and He., X. H., Pearce, B., Jardine, K, and McBurney, M. W. (2009) SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol. Oncogene 28, 2882-2893
-
(2009)
Oncogene
, vol.28
, pp. 2882-2893
-
-
Boily, G.1
He, X.H.2
Pearce, B.3
Jardine, K.4
McBurney, M.W.5
-
7
-
-
30544445468
-
Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells
-
DOI 10.1038/sj.onc.1209049, PII 1209049
-
Ota, H., Tokunaga, E., Chang, K, Hikasa, M., Iijima, K, Eto, M., Kozaki, K, Akishita, M., Ouchi, Y, and Kaneki, M. (2006) Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells. Oncogene 25, 176-185 (Pubitemid 43083679)
-
(2006)
Oncogene
, vol.25
, Issue.2
, pp. 176-185
-
-
Ota, H.1
Tokunaga, E.2
Chang, K.3
Hikasa, M.4
Iijima, K.5
Eto, M.6
Kozaki, K.7
Akishita, M.8
Ouchi, Y.9
Kaneki, M.10
-
8
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
DOI 10.1073/pnas.1934713100
-
Cheng, H. L., Mostoslavsky, R., Saito, S., Manis, J. P., Gu, Y., Patel, P., Bronson, R., Appella, E., and Alt., F. W., and Chua, K F. (2003) Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 100, 10794-10799 (Pubitemid 37140107)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.19
, pp. 10794-10799
-
-
Cheng, H.-L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
Bronson, R.7
Appella, E.8
Alt, F.W.9
Chua, K.F.10
-
9
-
-
34648837170
-
SIRT1 activation confers neuroprotection in experimental optic neuritis
-
DOI 10.1167/iovs.07-0131
-
Shindler, K. S., Ventura, E., Rex, T. S., Elliott, P., and Rostami, A. (2007) SIRT1 activation confers neuroprotection in experimental optic neuritis. Invest. Ophthalmol. Vis. Sci. 48, 3602-3609 (Pubitemid 351261095)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.8
, pp. 3602-3609
-
-
Shindler, K.S.1
Ventura, E.2
Rex, T.S.3
Elliott, P.4
Rostami, A.5
-
10
-
-
34250365395
-
+-dependent histone deacetylase SIRT1
-
DOI 10.1074/jbc.M609554200
-
Tanno, M., Sakamoto, J., Miura, T., Shimamoto, K, and Horio, Y. (2007) Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1. J. Biol. Chem. 282, 6823-6832 (Pubitemid 47100909)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.9
, pp. 6823-6832
-
-
Tanno, M.1
Sakamoto, J.2
Miura, T.3
Shimamoto, K.4
Horio, Y.5
-
11
-
-
35748962613
-
SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress
-
DOI 10.1038/ncb1645, PII NCB1645
-
Yang, Y, Fu, W., Chen, J., Olashaw, N., Zhang, X., Nicosia, S. V., Bhalla, K, and Bai, W. (2007) SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress. Nat. Cell Biol. 9, 1253-1262 (Pubitemid 350042357)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.11
, pp. 1253-1262
-
-
Yang, Y.1
Fu, W.2
Chen, J.3
Olashaw, N.4
Zhang, X.5
Nicosia, S.V.6
Bhalla, K.7
Bai, W.8
-
12
-
-
43049121395
-
Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
-
DOI 10.1016/j.devcel.2008.02.004, PII S1534580708000749
-
Fulco, M., Cen, Y, Zhao, P., and Hoffman., E. P., McBurney, M. W., Sauve, A A, and Sartorelli, V. (2008) Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev. Cell. 14, 661-673 (Pubitemid 351622608)
-
(2008)
Developmental Cell
, vol.14
, Issue.5
, pp. 661-673
-
-
Fulco, M.1
Cen, Y.2
Zhao, P.3
Hoffman, E.P.4
McBurney, M.W.5
Sauve, A.A.6
Sartorelli, V.7
-
13
-
-
8844247034
-
Silent information regulator 2α, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes
-
DOI 10.1161/01.RES.0000147557.75257.ff
-
Alcendor, R R, Kirshenbaum, L. A., Imai, S., Vatner, S. F., and Sadoshima, J. (2004) Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. Circ. Res. 95, 971-980 (Pubitemid 39532327)
-
(2004)
Circulation Research
, vol.95
, Issue.10
, pp. 971-980
-
-
Alcendor, R.R.1
Kirshenbaum, L.A.2
Imai, S.-I.3
Vatner, S.F.4
Sadoshima, J.5
-
14
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
DOI 10.1161/01.RES.0000267723.65696.4a
-
Alcendor, R. R., Gao, S., Zhai, P., Zablocki, D., Holle, E., Yu, X., Tian, B., Wagner, T., Vatner, S. F., and Sadoshima, J. (2007) Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ. Res. 100, 1512-1521 (Pubitemid 46834764)
-
(2007)
Circulation Research
, vol.100
, Issue.10
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
Zablocki, D.4
Holle, E.5
Yu, X.6
Tian, B.7
Wagner, T.8
Vatner, S.F.9
Sadoshima, J.10
-
15
-
-
54149090275
-
-
World Health Organization, Geneva, Switzerland/Ebrary, Inc., Palo Alto, CA, USA
-
Mathers, C, Fat, D. M., and Boerma, J. T., eds. (2008) The global burden of disease: 2004 update. World Health Organization, Geneva, Switzerland/Ebrary, Inc., Palo Alto, CA, USA
-
(2008)
The Global Burden of Disease: 2004 Update.
-
-
Mathers, C.1
Fat, D.M.2
Boerma, J.T.3
-
16
-
-
0032873703
-
Ischemia-reperfusion in the adult mouse heart influence of age
-
DOI 10.1016/S0531-5565(99)00031-5, PII S0531556599000315
-
Azhar, G., Gao, W., Liu, L. X., and Wei, J. Y. (1999) Ischemiareperfusion in the adult mouse heart influence of age. Exp. Gerontol. 34, 699-714 (Pubitemid 29420332)
-
(1999)
Experimental Gerontology
, vol.34
, Issue.5
, pp. 699-714
-
-
Azhar, G.1
Gao, W.2
Liu, L.3
Wei, J.Y.4
-
17
-
-
77954515012
-
Lack of SIRT1 (mammalian sirtuin 1) activity leads to liver steatosis in the SIRT1+/- Mice: A role of lipid mobilization and inflammation
-
Xu, F., Gao, Z., Zhang, J., Rivera, C. A., Yin, J., Weng, J., and Ye, J. (2010) Lack of SIRT1 (mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation. Endocrinology 151, 2504-2514
-
(2010)
Endocrinology
, vol.151
, pp. 2504-2514
-
-
Xu, F.1
Gao, Z.2
Zhang, J.3
Rivera, C.A.4
Yin, J.5
Weng, J.6
Ye, J.7
-
18
-
-
77954729858
-
Sumoylation and regulation of cardiac gene expression
-
Wang, J., and Schwartz, R.J. (2010) Sumoylation and regulation of cardiac gene expression. Circ. Res. 107, 19-29
-
(2010)
Circ. Res.
, vol.107
, pp. 19-29
-
-
Wang, J.1
Schwartz, R.J.2
-
19
-
-
38749137749
-
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
-
DOI 10.1038/nature06504, PII NATURE06504
-
Miller, E. J., Li, J., Leng, L., McDonald, C, Atsumi, T., Bucala, R, and Young, L. H. (2008) Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature 4 51, 578-582 (Pubitemid 351186266)
-
(2008)
Nature
, vol.451
, Issue.7178
, pp. 578-582
-
-
Miller, E.J.1
Li, J.2
Leng, L.3
McDonald, C.4
Atsumi, T.5
Bucala, R.6
Young, L.H.7
-
20
-
-
79959817748
-
Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling
-
Wang, J., Yang, L., Rezaie, A. R., and Li, J. (2011) Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling. J. Thromb. Haemost. 9, 1308-1317
-
(2011)
J. Thromb. Haemost.
, vol.9
, pp. 1308-1317
-
-
Wang, J.1
Yang, L.2
Rezaie, A.R.3
Li, J.4
-
21
-
-
80052322424
-
Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, akt, and JNK signaling in nondiabetic mice
-
Morrison, A., Yan, X., Tong, C., and Li, J. (2011) Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice. Am. J. Physiol. Heart Circ. Physiol. 301, H895-H902
-
(2011)
Am. J. Physiol. Heart Circ. Physiol.
, vol.301
-
-
Morrison, A.1
Yan, X.2
Tong, C.3
Li, J.4
-
22
-
-
77954959087
-
Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart
-
Ma, H., Wang, J., Thomas, D. P., Tong, C, Leng, L., Wang, W., Merk, M., Zierow, S., Bernhagen, J., Ren, J., Bucala, R., and Li, J. (2010) Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart. Circulation 122, 282-292
-
(2010)
Circulation
, vol.122
, pp. 282-292
-
-
Ma, H.1
Wang, J.2
Thomas, D.P.3
Tong, C.4
Leng, L.5
Wang, W.6
Merk, M.7
Zierow, S.8
Bernhagen, J.9
Ren, J.10
Bucala, R.11
Li, J.12
-
23
-
-
49549114451
-
Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats
-
Lin, J. F., and Lin., S. M., Chih, C. L., Nien, M. W., and Su., H. H., Hu, B. R., Huang, S. S., and Tsai, S. K (2008) Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats. Life Sci. 83, 313-317
-
(2008)
Life Sci.
, vol.83
, pp. 313-317
-
-
Lin, J.F.1
Lin, S.M.2
Chih, C.L.3
Nien, M.W.4
Su, H.H.5
Hu, B.R.6
Huang, S.S.7
Tsai, S.K.8
-
24
-
-
78149279712
-
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
-
DOI 10.1172/JCI200419297
-
Russell, R. R., 3rd, Li, J., Coven, D. L., Pypaert, M., Zechner, C, Palmeri, M., Giordano, F. J., Mu, J., Birnbaum, M. J., and Young, L. H. (2004) AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J. Clin. Invest. 114, 495-503 (Pubitemid 39572099)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.4
, pp. 495-503
-
-
Russell III, R.R.1
Li, J.2
Coven, D.L.3
Pypaert, M.4
Zechner, C.5
Palmeri, M.6
Giordano, F.J.7
Mu, J.8
Birnbaum, M.J.9
Young, L.H.10
-
25
-
-
77953508427
-
Overnutrition and maternal obesity in sheep pregnancy alter the JNK-IRS-1 signaling cascades and cardiac function in the fetal heart
-
Wang, J., Ma, H., Tong, C, Zhang, H., and Lawlis., G. B., Li, Y., Zang, M., Ren, J., and Nijland., M. J., Ford, S. P., Nathanielsz, P. W., and Li, J. (2010) Overnutrition and maternal obesity in sheep pregnancy alter the JNK-IRS-1 signaling cascades and cardiac function in the fetal heart. FASEBJ. 24, 2066-2076
-
(2010)
FASEBJ
, vol.24
, pp. 2066-2076
-
-
Wang, J.1
Ma, H.2
Tong, C.3
Zhang, H.4
Lawlis, G.B.5
Li, Y.6
Zang, M.7
Ren, J.8
Nijland, M.J.9
Ford, S.P.10
Nathanielsz, P.W.11
Li, J.12
-
26
-
-
78649679988
-
Macrophage migration inhibitory factor deficiency augments cardiac dysfunction in type 1 diabetic murine cardiomyocytes
-
Tong, C., Morrison, A., Yan, X., Zhao, P., and Yeung., E. D., Wang, J., Xie, J., and Li, J. (2010) Macrophage migration inhibitory factor deficiency augments cardiac dysfunction in type 1 diabetic murine cardiomyocytes. J. Diabetes. 2, 267-274
-
(2010)
J. Diabetes.
, vol.2
, pp. 267-274
-
-
Tong, C.1
Morrison, A.2
Yan, X.3
Zhao, P.4
Yeung, E.D.5
Wang, J.6
Xie, J.7
Li, J.8
-
27
-
-
84455162752
-
Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway
-
Yeung, E. D., Morrison, A., Plumeri, D., Wang, J., Tong, C., Yan, X., and Li, J. (2012) Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway. Prostate 72, 165-172
-
(2012)
Prostate
, vol.72
, pp. 165-172
-
-
Yeung, E.D.1
Morrison, A.2
Plumeri, D.3
Wang, J.4
Tong, C.5
Yan, X.6
Li, J.7
-
28
-
-
33749508911
-
CD44 Is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex
-
DOI 10.1016/j.immuni.2006.08.020, PII S1074761306004328
-
Shi, X., Leng, L., Wang, T., Wang, W., Du, X., Li, J., McDonald, C., Chen, Z., Murphy, J. W., Lolis, E., Noble, P., Knudson, W., and Bucala, R. (2006) CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity 25, 595-606 (Pubitemid 44529040)
-
(2006)
Immunity
, vol.25
, Issue.4
, pp. 595-606
-
-
Shi, X.1
Leng, L.2
Wang, T.3
Wang, W.4
Du, X.5
Li, J.6
McDonald, C.7
Chen, Z.8
Murphy, J.W.9
Lolis, E.10
Noble, P.11
Knudson, W.12
Bucala, R.13
-
29
-
-
15944406765
-
SUMO: A history of modification
-
DOI 10.1016/j.molcel.2005.03.012
-
Hay, R. T. (2005) SUMO: a history of modification. Mol Cell 18, 1-12 (Pubitemid 40444643)
-
(2005)
Molecular Cell
, vol.18
, Issue.1
, pp. 1-12
-
-
Hay, R.T.1
-
30
-
-
0032504021
-
Structure determination of the small ubiquitin-related modifier SUMO-1
-
DOI 10.1006/jmbi.1998.1839
-
Bayer, P., Arndt, A., Metzger, S., Mahajan, R., Melchior, F., Jaenicke, R., and Becker, J. (1998) Structure determination of the small ubiquitin-related modifier SUMO-1. J. Mol. Biol. 280, 275-286 (Pubitemid 28325519)
-
(1998)
Journal of Molecular Biology
, vol.280
, Issue.2
, pp. 275-286
-
-
Bayer, P.1
Arndt, A.2
Metzger, S.3
Mahajan, R.4
Melchior, F.5
Jaenicke, R.6
Becker, J.7
-
31
-
-
84857626547
-
Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction
-
Kim, E. Y, Chen, L., Ma, Y, Yu, W., Chang, J., Moskowitz, I. P., and Wang, J. (2012) Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J. Mol. Cell. Cardiol. 52, 638-649
-
(2012)
J. Mol. Cell. Cardiol.
, vol.52
, pp. 638-649
-
-
Kim, E.Y.1
Chen, L.2
Ma, Y.3
Yu, W.4
Chang, J.5
Moskowitz, I.P.6
Wang, J.7
-
32
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
-
DOI 10.1038/nature03354
-
Rodgers, J. T., Lerin, C., Haas, W., Gygi, S. P., and Spiegelman., B. M., and Puigserver, P. (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434, 113-118 (Pubitemid 40349395)
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
33
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Canto, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., and Elliott., P. J., Puigserver, P., and Auwerx, J. (2009) AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458, 1056-1060
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
34
-
-
36749087548
-
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
-
DOI 10.1038/nature06261, PII NATURE06261
-
Milne, J. C., and Lambert., P. D., Schenk, S., Carney, D. P., and Smith., J. J., Gagne, D.J., Jin, L., Boss, O., Perni, R. B., and Vu., C. B., Bemis, J. E., Xie, R., Disch, J. S., Ng, P. Y, Nunes, J. J., Lynch, A. V., Yang, H., Galonek, H., Israelian, K, Choy, W., Iffland, A., Lavu, S., Medvedik, O., Sinclair, D. A., Olefsky, J. M., Jirousek, M. R., Elliott, P. J., and Westphal, C. H. (2007) Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450, 712-716 (Pubitemid 350207685)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 712-716
-
-
Milne, J.C.1
Lambert, P.D.2
Schenk, S.3
Carney, D.P.4
Smith, J.J.5
Gagne, D.J.6
Jin, L.7
Boss, O.8
Perni, R.B.9
Vu, C.B.10
Bemis, J.E.11
Xie, R.12
Disch, J.S.13
Ng, P.Y.14
Nunes, J.J.15
Lynch, A.V.16
Yang, H.17
Galonek, H.18
Israelian, K.19
Choy, W.20
Iffland, A.21
Lavu, S.22
Medvedik, O.23
Sinclair, D.A.24
Olefsky, J.M.25
Jirousek, M.R.26
Elliott, P.J.27
Westphal, C.H.28
more..
-
35
-
-
0032539911
-
HL-1 cells: A cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte
-
DOI 10.1073/pnas.95.6.2979
-
Claycomb, W. C., and Lanson., N. A., Jr., Stallworth, B. S., Egeland, D. B., Delcarpio, J. B., Bahinski, A., and Izzo, N. J., Jr. (1998) HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc. Natl. Acad. Sci. U. S. A. 95, 2979-2984 (Pubitemid 28135840)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.6
, pp. 2979-2984
-
-
Claycomb, W.C.1
Lanson Jr., N.A.2
Stallworth, B.S.3
Egeland, D.B.4
Delcarpio, J.B.5
Bahinski, A.6
Izzo Jr., N.J.7
-
36
-
-
0034095121
-
Upregulation of p53 protein in rat heart subjected to a transient occlusion of the coronary artery followed by reperfusion
-
Xie, Z. L., Koyama, T., Abe, K, Fujii, Y., Sawa, H., and Nagashima, K (2000) Upregulation of p53 protein in rat heart subjected to a transient occlusion of the coronary artery followed by reperfusion. Jpn. J. Physiol. 50, 159-162 (Pubitemid 30243420)
-
(2000)
Japanese Journal of Physiology
, vol.50
, Issue.1
, pp. 159-162
-
-
Xie, Z.1
Koyama, T.2
Abe, K.3
Fujii, Y.4
Sawa, H.5
Nagashima, K.6
-
37
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
DOI 10.1016/S0092-8674(01)00527-X
-
Vaziri, H., Dessain, S. K, Eagon, E. N., and Imai., S. I., Frye, R. A., Pandita, T. K, Guarente, L., and Weinberg, R. A. (2001) hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107, 149-159 (Pubitemid 33035942)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.-I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
38
-
-
60649088334
-
Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate
-
Fukuda, I., Ito, A., Hirai, G., Nishimura, S., Kawasaki, H., Saitoh, H., Kimura, K, Sodeoka, M., and Yoshida, M. (2009) Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. Chem. Biol. 16, 133-140
-
(2009)
Chem. Biol.
, vol.16
, pp. 133-140
-
-
Fukuda, I.1
Ito, A.2
Hirai, G.3
Nishimura, S.4
Kawasaki, H.5
Saitoh, H.6
Kimura, K.7
Sodeoka, M.8
Yoshida, M.9
-
39
-
-
0037147318
-
A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast
-
DOI 10.1074/jbc.M207991200
-
Stade, K, Vogel, F., Schwienhorst, I., Meusser, B., Volkwein, C., Nentwig, B., Dohmen, R. J., and Sommer, T. (2002) A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast. J. Biol. Chem. 277, 49554-49561 (Pubitemid 36014394)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.51
, pp. 49554-49561
-
-
Stade, K.1
Vogel, F.2
Schwienhorst, I.3
Meusser, B.4
Volkwein, C.5
Nentwig, B.6
Dohmen, R.J.7
Sommer, T.8
-
40
-
-
77958550713
-
Ubiquitin/SUMO modification regulates VHL protein stability and nucleocytoplasmic localization
-
Cai, Q., and Robertson, E. S. (2010) Ubiquitin/SUMO modification regulates VHL protein stability and nucleocytoplasmic localization. PLoS One 5, e12636
-
(2010)
PLoS One
, vol.5
-
-
Cai, Q.1
Robertson, E.S.2
-
41
-
-
34547113757
-
Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation
-
DOI 10.1074/jbc.M611041200
-
Wei, F., and Scholer., H. R., and Atchison, M. L. (2007) Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation. J. Biol. Chem. 282, 21551-21560 (Pubitemid 47099909)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.29
, pp. 21551-21560
-
-
Wei, F.1
Scholer, H.R.2
Atchison, M.L.3
-
42
-
-
0037011958
-
P53 mutant mice that display early ageing-associated phenotypes
-
DOI 10.1038/415045a
-
Tyner, S. D., Venkatachalam, S., Choi, J., Jones, S., Ghebranious, N., Igelmann, H., Lu, X. B., Soron, G., Cooper, B., Brayton, C., Park, S. H., Thompson, T., Karsenty, G., Bradley, A., and Donehower, L. A. (2002) p53 mutant mice that display early ageing-associated phenotypes. Nature 415, 45-53 (Pubitemid 34062443)
-
(2002)
Nature
, vol.415
, Issue.6867
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
Jones, S.4
Ghebranious, N.5
Igelmann, H.6
Lu, X.7
Soron, G.8
Cooper, B.9
Brayton, C.10
Sang, H.P.11
Thompson, T.12
Karsenty, G.13
Bradley, A.14
Donehower, L.A.15
-
43
-
-
46649083580
-
Aging and dietary restriction effects on ubiquitination, sumoylation, and the proteasome in the heart
-
Li, F., Zhang, L., Craddock, J., Bruce-Keller, A. J., Dasuri, K, Nguyen, A., and Keller, J. N. (2008) Aging and dietary restriction effects on ubiquitination, sumoylation, and the proteasome in the heart. Mech. Ageing Dev. 129, 515-521
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 515-521
-
-
Li, F.1
Zhang, L.2
Craddock, J.3
Bruce-Keller, A.J.4
Dasuri, K.5
Nguyen, A.6
Keller, J.N.7
-
44
-
-
78650172708
-
Silent information regulator 1 protects the heart from ischemia/reperfusion
-
Hsu, C. P., Zhai, P., Yamamoto, T., Maejima, Y, Matsushima, S., Hariharan, N., Shao, D., Takagi, H., Oka, S., and Sadoshima, J. (2010) Silent information regulator 1 protects the heart from ischemia/reperfusion. Circulation 122, 2170-2182
-
(2010)
Circulation
, vol.122
, pp. 2170-2182
-
-
Hsu, C.P.1
Zhai, P.2
Yamamoto, T.3
Maejima, Y.4
Matsushima, S.5
Hariharan, N.6
Shao, D.7
Takagi, H.8
Oka, S.9
Sadoshima, J.10
-
45
-
-
33750445309
-
NAD metabolism and sirtuins: Metabolic regulation of protein deacetylation in stress and toxicity
-
DOI 10.1208/aapsj080472
-
Yang, T. L., and Sauve, A. A. (2006) NAD metabolism and sirtuins: Metabolic regulation of protein deacetylation in stress and toxicity. AAPS J. 8, E632-E643 (Pubitemid 44644162)
-
(2006)
AAPS Journal
, vol.8
, Issue.4
-
-
Yang, T.1
Sauve, A.A.2
-
47
-
-
0036724599
-
Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex
-
Zhang, H., Saitoh, H., and Matunis, M.J. (2002) Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex. Mol. Cell. Biol. 22, 6498-6508
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6498-6508
-
-
Zhang, H.1
Saitoh, H.2
Matunis, M.J.3
-
48
-
-
63549094179
-
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
-
Smith, J. J., and Kenney., R. D., Gagne, D. J., Frushour, B. P., Ladd, W., and Galonek., H. L., Israelian, K, Song, J., Razvadauskaite, G., Lynch, A. V., Carney, D. P., Johnson, R. J., Lavu, S., Iffland, A., Elliott, P. J., Lambert, P. D., Elliston, K. O., Jirousek, M. R., Milne, J. C., and Boss, O. (2009) Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo. BMC Syst. Biol. 3, 31
-
(2009)
BMC Syst. Biol.
, vol.3
, pp. 31
-
-
Smith, J.J.1
Kenney, R.D.2
Gagne, D.J.3
Frushour, B.P.4
Ladd, W.5
Galonek, H.L.6
Israelian, K.7
Song, J.8
Razvadauskaite, G.9
Lynch, A.V.10
Carney, D.P.11
Johnson, R.J.12
Lavu, S.13
Iffland, A.14
Elliott, P.J.15
Lambert, P.D.16
Elliston, K.O.17
Jirousek, M.R.18
Milne, J.C.19
Boss, O.20
more..
|