-
1
-
-
0036083491
-
Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats
-
Abete P, Testa G, Ferrara N, De Santis D, Capaccio P, Viati L, Calabrese C, Cacciatore F, Longobardi G, Condorelli M, Napoli C, Rengo F (2002) Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats. Am J Physiol Heart Circ Physiol 282: H1978-H1987.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
-
-
Abete, P.1
Testa, G.2
Ferrara, N.3
De Santis, D.4
Capaccio, P.5
Viati, L.6
Calabrese, C.7
Cacciatore, F.8
Longobardi, G.9
Condorelli, M.10
Napoli, C.11
Rengo, F.12
-
2
-
-
19944432303
-
Tandem action of exercise training and food restriction completely preserves ischemic preconditioning in the aging heart
-
Abete P, Testa G, Galizia G, Mazzella F, Della Morte D, de Santis D, Calabrese C, Cacciatore F, Gargiulo G, Ferrara N, Rengo G, Sica V, Napoli C, Rengo F (2005) Tandem action of exercise training and food restriction completely preserves ischemic preconditioning in the aging heart. Exp Gerontol 40: 43-50.
-
(2005)
Exp Gerontol
, vol.40
, pp. 43-50
-
-
Abete, P.1
Testa, G.2
Galizia, G.3
Mazzella, F.4
della Morte, D.5
de Santis, D.6
Calabrese, C.7
Cacciatore, F.8
Gargiulo, G.9
Ferrara, N.10
Rengo, G.11
Sica, V.12
Napoli, C.13
Rengo, F.14
-
3
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
Adams JM, Cory S (2007) The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337.
-
(2007)
Oncogene
, vol.26
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
4
-
-
0033772264
-
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28
-
Alexander C, Votruba M, Pesch UE, Thiselton DL, Mayer S et al (2000) OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nat Genet 26: 211-215.
-
(2000)
Nat Genet
, vol.26
, pp. 211-215
-
-
Alexander, C.1
Votruba, M.2
Pesch, U.E.3
Thiselton, D.L.4
Mayer, S.5
-
5
-
-
69449106873
-
Autophagy is required for extension of yeast chronological life span by rapamycin
-
Alvers AL, Wood MS, Hu D, Kaywell AC, Dunn WA, Aris JP (2009) Autophagy is required for extension of yeast chronological life span by rapamycin. Autophagy 5: 847-849.
-
(2009)
Autophagy
, vol.5
, pp. 847-849
-
-
Alvers, A.L.1
Wood, M.S.2
Hu, D.3
Kaywell, A.C.4
Dunn, W.A.5
Aris, J.P.6
-
6
-
-
68949125118
-
OPA1-associated disorders: phenotypes and pathophysiology
-
Amati-Bonneau P, Milea D, Bonneau D, Chevrollier A, Ferré M et al (2009) OPA1-associated disorders: phenotypes and pathophysiology. Int J Biochem Cell Biol 41: 1855-1865.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1855-1865
-
-
Amati-Bonneau, P.1
Milea, D.2
Bonneau, D.3
Chevrollier, A.4
Ferré, M.5
-
8
-
-
77952083662
-
Rapamycin extends maximal lifespan in cancer-prone mice
-
Anisimov VN, Zabezhinski MA, Popovich IG, Piskunova TS, Semenchenko AV, Tyndyk ML et al (2010) Rapamycin extends maximal lifespan in cancer-prone mice. Am J Pathol 176: 2092-2097.
-
(2010)
Am J Pathol
, vol.176
, pp. 2092-2097
-
-
Anisimov, V.N.1
Zabezhinski, M.A.2
Popovich, I.G.3
Piskunova, T.S.4
Semenchenko, A.V.5
Tyndyk, M.L.6
-
9
-
-
68949132677
-
From mitochondrial dynamics and arrhythmias
-
Aon MA, Cortassa S, Akar FG, Brown DA, Zhou L, ÓRourke B (2009) From mitochondrial dynamics and arrhythmias. Int J Biochem Cell Biol 41: 1940-1948.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1940-1948
-
-
Aon, M.A.1
Cortassa, S.2
Akar, F.G.3
Brown, D.A.4
Zhou, L.5
ÓRourke, B.6
-
10
-
-
20644434910
-
Mitochondrial K(ATP) channels in cell survival and death
-
Ardehali H, O'Rourke B (2005) Mitochondrial K(ATP) channels in cell survival and death. J Mol Cell Cardiol 39: 7-16.
-
(2005)
J Mol Cell Cardiol
, vol.39
, pp. 7-16
-
-
Ardehali, H.1
O'Rourke, B.2
-
11
-
-
33845885125
-
Mitochondrial fragmentation in apoptosis
-
Arnoult D (2007) Mitochondrial fragmentation in apoptosis. Trends Cell Biol 17: 6-12.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 6-12
-
-
Arnoult, D.1
-
12
-
-
33947235594
-
Exercise-induced cardioprotection: biochemical morphological functional evidence in whole tissue and isolated mitochondria
-
Ascensão A, Frereira R, Magalhães J (2007) Exercise-induced cardioprotection: biochemical morphological functional evidence in whole tissue and isolated mitochondria. Int J Cardiol 117: 16-30.
-
(2007)
Int J Cardiol
, vol.117
, pp. 16-30
-
-
Ascensão, A.1
Frereira, R.2
Magalhães, J.3
-
13
-
-
0037593949
-
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity
-
Bach D, Pich S, Soriano FX, Vega N, Baumgartner B, Oriola J et al (2003) Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem 278: 17190-17197.
-
(2003)
J Biol Chem
, vol.278
, pp. 17190-17197
-
-
Bach, D.1
Pich, S.2
Soriano, F.X.3
Vega, N.4
Baumgartner, B.5
Oriola, J.6
-
14
-
-
24144462451
-
Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6
-
Bach D, Naon D, Pich S, Soriano FX, Vega N, Rieusset J et al (2005) Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6. Diabetes 54: 2685-2693.
-
(2005)
Diabetes
, vol.54
, pp. 2685-2693
-
-
Bach, D.1
Naon, D.2
Pich, S.3
Soriano, F.X.4
Vega, N.5
Rieusset, J.6
-
16
-
-
37749043369
-
Mitochondrial dynamics and peripheral neurophathy
-
Baloh RH (2008) Mitochondrial dynamics and peripheral neurophathy. Neuroscientist 14(1): 12-18.
-
(2008)
Neuroscientist
, vol.14
, Issue.1
, pp. 12-18
-
-
Baloh, R.H.1
-
17
-
-
0033972463
-
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
-
Barja G, Herrero A (2000) Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J 14: 312-318.
-
(2000)
FASEB J
, vol.14
, pp. 312-318
-
-
Barja, G.1
Herrero, A.2
-
18
-
-
9644262490
-
Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae
-
Barros MH, Bandy B, Tahara EB, Kowaltowski AJ (2004) Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae. J Biol Chem 279: 49883-49888.
-
(2004)
J Biol Chem
, vol.279
, pp. 49883-49888
-
-
Barros, M.H.1
Bandy, B.2
Tahara, E.B.3
Kowaltowski, A.J.4
-
19
-
-
77956187689
-
Yeast as a model to study mitochondrial mechanisms in ageing
-
Barros MH, da Cunha FM, Oliveira GA, Tahara EB, Kowaltowski AJ (2010) Yeast as a model to study mitochondrial mechanisms in ageing. Mech Ageing Dev 131: 494-502.
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 494-502
-
-
Barros, M.H.1
da Cunha, F.M.2
Oliveira, G.A.3
Tahara, E.B.4
Kowaltowski, A.J.5
-
20
-
-
21544477514
-
At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products
-
Basta G, Lazzerini G, Del Turo S, Ratto GM, Schmidt AM, DeCaterina R (2005) At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products. Arterioscler Thromb Vasc Biol 25: 1401-1407.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1401-1407
-
-
Basta, G.1
Lazzerini, G.2
Del Turo, S.3
Ratto, G.M.4
Schmidt, A.M.5
DeCaterina, R.6
-
21
-
-
39149145854
-
In vivo reactive oxygen species production induced by ischemia in muscle arterioles of mice: involvement of xanthine oxidase and mitochondria
-
Baudry N, Laemmel E, Vicaut E (2008) In vivo reactive oxygen species production induced by ischemia in muscle arterioles of mice: involvement of xanthine oxidase and mitochondria. Am J Physiol Heart Circ Physiol 294: H821-H828.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Baudry, N.1
Laemmel, E.2
Vicaut, E.3
-
22
-
-
25444474703
-
Mitochondria take center stage in aging and neurodegeneration
-
Beal MF (2005) Mitochondria take center stage in aging and neurodegeneration. Ann Neurol 58: 495-505.
-
(2005)
Ann Neurol
, vol.58
, pp. 495-505
-
-
Beal, M.F.1
-
23
-
-
34047173074
-
Mitochondrial bioenergetics and structural network organization
-
Benard G, Bellance N, James D, Parrone P, Fernandez H, Lettellier T, Rossignol R (2007) Mitochondrial bioenergetics and structural network organization. J Cell Sci 120: 838-848.
-
(2007)
J Cell Sci
, vol.120
, pp. 838-848
-
-
Benard, G.1
Bellance, N.2
James, D.3
Parrone, P.4
Fernandez, H.5
Lettellier, T.6
Rossignol, R.7
-
24
-
-
80053637543
-
Effects of aging and calorie restriction on white matter in rhesus macaques
-
Bendlin BB, Canu E, Willette A, Kastman EK, McLaren DG et al (2011) Effects of aging and calorie restriction on white matter in rhesus macaques. Neurobiol Aging 32(12): 2319e1-2319e11.
-
(2011)
Neurobiol Aging
, vol.32
, Issue.12
-
-
Bendlin, B.B.1
Canu, E.2
Willette, A.3
Kastman, E.K.4
McLaren, D.G.5
-
25
-
-
38049012963
-
Poly(ADP-ribosyl)ation in mammal ageing
-
Beneke S, Bürkle A (2007) Poly(ADP-ribosyl)ation in mammal ageing. Nucleic Acids Res 35(22): 7456-7465.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.22
, pp. 7456-7465
-
-
Beneke, S.1
Bürkle, A.2
-
26
-
-
77953081730
-
Enzyme characteristics of recombinant poly(ADP-ribose) polymerases-1 of rat and human origin mirror the correlation between cellular poly(ADP-ribosyl)ation capacity and species-specific life span
-
Beneke S, Scherr A-L, Ponath V, Popp O, Bürkle A (2010) Enzyme characteristics of recombinant poly(ADP-ribose) polymerases-1 of rat and human origin mirror the correlation between cellular poly(ADP-ribosyl)ation capacity and species-specific life span. Mech Ageing Dev 131: 366-369.
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 366-369
-
-
Beneke, S.1
Scherr, A.-L.2
Ponath, V.3
Popp, O.4
Bürkle, A.5
-
28
-
-
0028047262
-
Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria
-
Bereiter-Hahn J, Vöth M (1994) Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria. Mircrosc Res Techn 27: 198-219.
-
(1994)
Mircrosc Res Techn
, vol.27
, pp. 198-219
-
-
Bereiter-Hahn, J.1
Vöth, M.2
-
31
-
-
41449095822
-
Autophagy functions in programmed cell death
-
Berry DL, Baehrecke EH (2008) Autophagy functions in programmed cell death. Autophagy 4: 359-360.
-
(2008)
Autophagy
, vol.4
, pp. 359-360
-
-
Berry, D.L.1
Baehrecke, E.H.2
-
32
-
-
0027371027
-
Morphological plasticity of synaptic mitochondria during aging
-
Bertoni-Freddari C, Fattoretti P, Casoli T, Meier-Ruge W, Ulrich J (1993) Morphological plasticity of synaptic mitochondria during aging. Brain Res 628: 193-200.
-
(1993)
Brain Res
, vol.628
, pp. 193-200
-
-
Bertoni-Freddari, C.1
Fattoretti, P.2
Casoli, T.3
Meier-Ruge, W.4
Ulrich, J.5
-
33
-
-
0037292417
-
Inverse correlation between mitochondrial size and metabolic competence: a quantitative cytochemical study of cytochrome oxidase activity
-
Bertoni-Freddari C, Fattoretti P, Paolini R, Caselli U, Giorgetti B, Solazzi M (2003) Inverse correlation between mitochondrial size and metabolic competence: a quantitative cytochemical study of cytochrome oxidase activity. Naturwi 90: 68-71.
-
(2003)
Naturwi
, vol.90
, pp. 68-71
-
-
Bertoni-Freddari, C.1
Fattoretti, P.2
Paolini, R.3
Caselli, U.4
Giorgetti, B.5
Solazzi, M.6
-
34
-
-
2342464382
-
Role of mitochondrial deterioration in physiological and pathological brain aging
-
Bertoni-Freddari C, Fattoretti P, Giorgetti B, Solazzi M, Balietti M, Meier-Ruge W (2004) Role of mitochondrial deterioration in physiological and pathological brain aging. Gerontology 50: 187-192.
-
(2004)
Gerontology
, vol.50
, pp. 187-192
-
-
Bertoni-Freddari, C.1
Fattoretti, P.2
Giorgetti, B.3
Solazzi, M.4
Balietti, M.5
Meier-Ruge, W.6
-
35
-
-
13844270599
-
Age-related decline in metabolic competence of small and medium-sized synaptic mitochondria
-
Bertoni-Freddari C, Fattoretti P, Giorgetti B, Spazzafumo L, Solazzi M, Balietti M (2005) Age-related decline in metabolic competence of small and medium-sized synaptic mitochondria. Naturwi 92: 82-85.
-
(2005)
Naturwi
, vol.92
, pp. 82-85
-
-
Bertoni-Freddari, C.1
Fattoretti, P.2
Giorgetti, B.3
Spazzafumo, L.4
Solazzi, M.5
Balietti, M.6
-
36
-
-
34249891333
-
Two neurons mediate diet restriction-induced longevity in C. elegans
-
Bishop NA, Guarente L (2007) Two neurons mediate diet restriction-induced longevity in C. elegans. Nature 447(7144): 545-549.
-
(2007)
Nature
, vol.447
, Issue.7144
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
37
-
-
55849152355
-
Aging: ROS or TOR
-
Blagosklonny MV (2008) Aging: ROS or TOR. Cell Cycle 7(21): 3344-3354.
-
(2008)
Cell Cycle
, vol.7
, Issue.21
, pp. 3344-3354
-
-
Blagosklonny, M.V.1
-
38
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
Bluher M, Kahn BB, Kahn CR (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Sci 299: 572-574.
-
(2003)
Sci
, vol.299
, pp. 572-574
-
-
Bluher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
39
-
-
21744434924
-
Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning
-
Boengler K, Dodoni G, Rodriguez-Sinovas A, Cabestrero A, Ruiz-Meana M, Gres P et al (2005) Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning. Cardiovasc Res 67: 234-244.
-
(2005)
Cardiovasc Res
, vol.67
, pp. 234-244
-
-
Boengler, K.1
Dodoni, G.2
Rodriguez-Sinovas, A.3
Cabestrero, A.4
Ruiz-Meana, M.5
Gres, P.6
-
40
-
-
34147188924
-
Loss of ischemic preconditioning's cardioprotection in aged mouse hearts is associated with reduced gap junctional and mitochondrial levels of connexin 43
-
Boengler K, Konietzka I, Buechert A, Heinen Y, Garcia-Dorado D, Heusch G et al (2007) Loss of ischemic preconditioning's cardioprotection in aged mouse hearts is associated with reduced gap junctional and mitochondrial levels of connexin 43. Am J Physiol Heart Circ Physiol 292: H1764-H1769.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Boengler, K.1
Konietzka, I.2
Buechert, A.3
Heinen, Y.4
Garcia-Dorado, D.5
Heusch, G.6
-
41
-
-
0029165277
-
DNA damage, mutation and fine structure DNA repair in aging
-
Bohr VA, Anson RM (1995) DNA damage, mutation and fine structure DNA repair in aging. Mutation Res 338(1-6): 25-34.
-
(1995)
Mutation Res
, vol.338
, Issue.1-6
, pp. 25-34
-
-
Bohr, V.A.1
Anson, R.M.2
-
42
-
-
0037029132
-
Mitochondrial DNA repair of oxidative damage in mammalian cells
-
Bohr VA, Stevnsner T, de Souza-Pinto NC (2002) Mitochondrial DNA repair of oxidative damage in mammalian cells. Gene 286: 127-134.
-
(2002)
Gene
, vol.286
, pp. 127-134
-
-
Bohr, V.A.1
Stevnsner, T.2
de Souza-Pinto, N.C.3
-
43
-
-
36248975293
-
SIRT1 transgenic mice show phenotypes resembling calorie restriction
-
Bordone L, Cohen D, Robinson A, Motta MC, van Veen E, Czopik A, Steele AD, Crowe H, Marmor S, Luo J et al (2007) SIRT1 transgenic mice show phenotypes resembling calorie restriction. Aging Cell 6: 759-767.
-
(2007)
Aging Cell
, vol.6
, pp. 759-767
-
-
Bordone, L.1
Cohen, D.2
Robinson, A.3
Motta, M.C.4
van Veen, E.5
Czopik, A.6
Steele, A.D.7
Crowe, H.8
Marmor, S.9
Luo, J.10
-
45
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134: 707-716.
-
(1973)
Biochem J
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
46
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dorken B, Jenuwein T, Schmitt CA (2005) Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436: 660-665.
-
(2005)
Nature
, vol.436
, pp. 660-665
-
-
Braig, M.1
Lee, S.2
Loddenkemper, C.3
Rudolph, C.4
Peters, A.H.5
Schlegelberger, B.6
Stein, H.7
Dorken, B.8
Jenuwein, T.9
Schmitt, C.A.10
-
47
-
-
84866037994
-
The role of mitochondria in the aging processes of yeast
-
In: M. Breitenbach et al. (eds.), doi: 10. 1007/978-94-007-2561-4_3
-
Breitenbach M, Laun P, Dickinson JR, Klocker A, et al. (2012) The role of mitochondria in the aging processes of yeast. In: M. Breitenbach et al. (eds.), Aging Research in Yeast, Subcellular Biochemistry 57. doi: 10. 1007/978-94-007-2561-4_3.
-
(2012)
Aging Research in Yeast, Subcellular Biochemistry
, vol.57
-
-
Breitenbach, M.1
Laun, P.2
Dickinson, J.R.3
Klocker, A.4
-
48
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
49
-
-
0036236006
-
The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis
-
Brunk UT, Terman A (2002) The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur J Biochem 269: 1996-2002.
-
(2002)
Eur J Biochem
, vol.269
, pp. 1996-2002
-
-
Brunk, U.T.1
Terman, A.2
-
50
-
-
0033850407
-
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
-
Buee L, Bussiere T, Buee-Scherrer V, Delacourte A, Hot PR (2000) Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res Rev 33: 95-130.
-
(2000)
Brain Res Rev
, vol.33
, pp. 95-130
-
-
Buee, L.1
Bussiere, T.2
Buee-Scherrer, V.3
Delacourte, A.4
Hot, P.R.5
-
51
-
-
77749264564
-
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-δ: implications for vascular disease
-
Cai W, Torreggiani M, Zhu L, Chen X, He JC, Striker GE, Vlassara H (2010) AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-δ: implications for vascular disease. Am J Physiol Cell Physiol 298: C624-C634.
-
(2010)
Am J Physiol Cell Physiol
, vol.298
-
-
Cai, W.1
Torreggiani, M.2
Zhu, L.3
Chen, X.4
He, J.C.5
Striker, G.E.6
Vlassara, H.7
-
52
-
-
2942531063
-
Mitochondrial defects in cancer
-
Carew JS, Huang P (2002) Mitochondrial defects in cancer. Mol Cancer 1: 9.
-
(2002)
Mol Cancer
, vol.1
, pp. 9
-
-
Carew, J.S.1
Huang, P.2
-
53
-
-
23844494686
-
Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise
-
Cartoni R, Leger B, Hock MB, Praz M, Crettenand A, Pich S et al (2005) Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise. J Physiol 567: 349-358.
-
(2005)
J Physiol
, vol.567
, pp. 349-358
-
-
Cartoni, R.1
Leger, B.2
Hock, M.B.3
Praz, M.4
Crettenand, A.5
Pich, S.6
-
54
-
-
84155165077
-
Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys
-
Castro MR, Suarez E, Kraselburd E, Isidro A, Paz J, Ferder L, Ayala-Torres S (2012) Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys. Exptl Gerontol 47(1): 29-37.
-
(2012)
Exptl Gerontol
, vol.47
, Issue.1
, pp. 29-37
-
-
Castro, M.R.1
Suarez, E.2
Kraselburd, E.3
Isidro, A.4
Paz, J.5
Ferder, L.6
Ayala-Torres, S.7
-
55
-
-
65449139544
-
Mitochondria, calcium and cell death: a deadly triad in neurodegeneration
-
Celsi F, Pizzo P, Brini M, Leo S, Fotino C et al (2009) Mitochondria, calcium and cell death: a deadly triad in neurodegeneration. Biochim Biophys Acta 1787: 335-344.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 335-344
-
-
Celsi, F.1
Pizzo, P.2
Brini, M.3
Leo, S.4
Fotino, C.5
-
56
-
-
77951096150
-
Mitochondrial dynamics-fusion, fission, movement and mitophagy-in neurodegenerative diseases
-
Chen H, Chan DC (2009) Mitochondrial dynamics-fusion, fission, movement and mitophagy-in neurodegenerative diseases. Human Mol Gen 18(2): R169-R179.
-
(2009)
Human Mol Gen
, vol.18
, Issue.2
-
-
Chen, H.1
Chan, D.C.2
-
57
-
-
0033840947
-
Age- and myopathy-dependent changes in connexins of normal and cardiomyopathic Syrian hamster ventricular myocardium
-
Chen M, Jones DL (2000) Age- and myopathy-dependent changes in connexins of normal and cardiomyopathic Syrian hamster ventricular myocardium. Can J Physiol Pharmacol 78: 669-678.
-
(2000)
Can J Physiol Pharmacol
, vol.78
, pp. 669-678
-
-
Chen, M.1
Jones, D.L.2
-
58
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC (2003) Mitofusins Mfn1 and Mfn2coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160: 189-200.
-
(2003)
J Cell Biol
, vol.160
, pp. 189-200
-
-
Chen, H.1
Detmer, S.A.2
Ewald, A.J.3
Griffin, E.E.4
Fraser, S.E.5
Chan, D.C.6
-
59
-
-
22544451586
-
Disruption of fusion results in mitochondrial heterogeneity and dysfunction
-
Chen H, Chomyn A, Chan DC (2005a) Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J Biol Chem 280: 26185-26192.
-
(2005)
J Biol Chem
, vol.280
, pp. 26185-26192
-
-
Chen, H.1
Chomyn, A.2
Chan, D.C.3
-
60
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA et al (2005b) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436: 725-730.
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
Lin, H.K.4
Dotan, Z.A.5
-
61
-
-
34547601410
-
Mitochondrial fusion protects against neurodegeneration in the cerebellum
-
Chen H, McCaffery A, Chan DC (2007) Mitochondrial fusion protects against neurodegeneration in the cerebellum. Cell 130: 548-562.
-
(2007)
Cell
, vol.130
, pp. 548-562
-
-
Chen, H.1
McCaffery, A.2
Chan, D.C.3
-
62
-
-
40849139513
-
Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats
-
Chicco AJ, McCune SA, Emter CA, Sparagna GC, Rees ML, Bolden DA, Marshall KD, Murphy RC, Moore RL (2008) Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats. Hypertension 51: 1096-1102.
-
(2008)
Hypertension
, vol.51
, pp. 1096-1102
-
-
Chicco, A.J.1
McCune, S.A.2
Emter, C.A.3
Sparagna, G.C.4
Rees, M.L.5
Bolden, D.A.6
Marshall, K.D.7
Murphy, R.C.8
Moore, R.L.9
-
63
-
-
79954632356
-
The role of mitochondria in Drosophila aging
-
Cho J, Hur JH, Walker DW (2011) The role of mitochondria in Drosophila aging. Exp Gerontol 46: 331-334.
-
(2011)
Exp Gerontol
, vol.46
, pp. 331-334
-
-
Cho, J.1
Hur, J.H.2
Walker, D.W.3
-
64
-
-
33745685054
-
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling
-
Cipolat S, Rudka T, Hartmann D, Costa V, Serneels L, Craessaerts K et al (2006) Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. Cell 126: 163-175.
-
(2006)
Cell
, vol.126
, pp. 163-175
-
-
Cipolat, S.1
Rudka, T.2
Hartmann, D.3
Costa, V.4
Serneels, L.5
Craessaerts, K.6
-
65
-
-
23244447893
-
Tumour biology: senescence in premalignant tumours
-
Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguria A, Zaballos A, Flores JM, Barbacid M et al (2005) Tumour biology: senescence in premalignant tumours. Nature 436: 642.
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Barradas, M.6
Benguria, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
-
66
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R (2009) Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 325: 201-204.
-
(2009)
Science
, vol.325
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
Kastman, E.K.4
Kosmatka, K.J.5
Beasley, T.M.6
Allison, D.B.7
Cruzen, C.8
Simmons, H.A.9
Kemnitz, J.W.10
Weindruch, R.11
-
67
-
-
84864954362
-
Mitochondrial dynamics in cancer and neurodegenerative and neuroinflammatory diseases
-
doi:10.1155/2012/729290
-
Corrado M, Scorrano L, Campello S (2012) Mitochondrial dynamics in cancer and neurodegenerative and neuroinflammatory diseases. Int J Cell Biol. doi: 10. 1155/2012/729290.
-
(2012)
Int J Cell Biol
-
-
Corrado, M.1
Scorrano, L.2
Campello, S.3
-
68
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age
-
Corral-Debrinski M, Horton T, Lott MT, Shoffner JM, Beal MF, Wallace DC (1992) Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age. Nat Genet 2: 324-329.
-
(1992)
Nat Genet
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
69
-
-
0009933968
-
Mitochondrial distributions in hearts of male rats as a function of aging
-
Cosmas AC, Edington DW, Manfredi TG (1994) Mitochondrial distributions in hearts of male rats as a function of aging. Age 17: 158.
-
(1994)
Age
, vol.17
, pp. 158
-
-
Cosmas, A.C.1
Edington, D.W.2
Manfredi, T.G.3
-
70
-
-
65249153029
-
RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes
-
Coughlan MT, Thorburn DR, Penfold SA, Laskowski A, Harcour BE et al (2009) RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes. J Am Soc Nephrol 20: 742-752.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 742-752
-
-
Coughlan, M.T.1
Thorburn, D.R.2
Penfold, S.A.3
Laskowski, A.4
Harcour, B.E.5
-
71
-
-
84861674629
-
Mitochondria as a central sensor for axonal degenerative stimuli
-
Court FA, Coleman MP (2012) Mitochondria as a central sensor for axonal degenerative stimuli. Trends in Neurosci 35(6): 364-372.
-
(2012)
Trends in Neurosci
, vol.35
, Issue.6
, pp. 364-372
-
-
Court, F.A.1
Coleman, M.P.2
-
72
-
-
0030881789
-
Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells
-
Croteau DL, Bohr VA (1997) Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J Biol Chem 272: 25409-25412.
-
(1997)
J Biol Chem
, vol.272
, pp. 25409-25412
-
-
Croteau, D.L.1
Bohr, V.A.2
-
73
-
-
84873627310
-
Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells
-
Csiszar A, Sosnowska D, Tucsek Z, Gautam T, Toth P et al (2012) Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. J Gerontol Ser A 68(3): 235-249.
-
(2012)
J Gerontol Ser A
, vol.68
, Issue.3
, pp. 235-249
-
-
Csiszar, A.1
Sosnowska, D.2
Tucsek, Z.3
Gautam, T.4
Toth, P.5
-
74
-
-
84861857638
-
Aerobic exercise training upregulates skeletal muscle calpain and ubiquitin-proteasome systems in healthy mice
-
Cunha TF, Moreira JB, Paixão NA, Campos JC, Monteiro AW, Bacurau AV, Bueno CR Jr, Ferreira JC, Brum PC (2012) Aerobic exercise training upregulates skeletal muscle calpain and ubiquitin-proteasome systems in healthy mice. J Appl Physiol 112: 1839-1846.
-
(2012)
J Appl Physiol
, vol.112
, pp. 1839-1846
-
-
Cunha, T.F.1
Moreira, J.B.2
Paixão, N.A.3
Campos, J.C.4
Monteiro, A.W.5
Bacurau, A.V.6
Bueno Jr., C.R.7
Ferreira, J.C.8
Brum, P.C.9
-
75
-
-
77951264436
-
Cardiac aging in mice and humans: the role of mitochondrial oxidative stress
-
Dai D-F, Rabinovitch PS (2009) Cardiac aging in mice and humans: the role of mitochondrial oxidative stress. Trends Cardiovasc med 19(7): 213-220.
-
(2009)
Trends Cardiovasc Med
, vol.19
, Issue.7
, pp. 213-220
-
-
Dai, D.-F.1
Rabinovitch, P.S.2
-
76
-
-
34447314190
-
Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function
-
Davies VJ, Hollins AJ, Piechota MJ, YipW DJR, White KE et al (2007) Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function. Hum Mol Genet 16: 1307-1318.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1307-1318
-
-
Davies, V.J.1
Hollins, A.J.2
Piechota, M.J.3
Yip, W.D.J.R.4
White, K.E.5
-
77
-
-
38349000606
-
Mitofusin 2: a mitochondria-shaping protein with signaling roles beyond fusion
-
De Brito OM, Scorrano L (2008) Mitofusin 2: a mitochondria-shaping protein with signaling roles beyond fusion. Antiox Redox Signal 10: 621-633.
-
(2008)
Antiox Redox Signal
, vol.10
, pp. 621-633
-
-
De Brito, O.M.1
Scorrano, L.2
-
78
-
-
20244381365
-
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein is mutated in dominant optic atrophy
-
Delettre C, Lenaers G, Griffoin JM, Gigarel N, Lorenzo C et al (2000) Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein is mutated in dominant optic atrophy. Nat Genet 26: 207-210.
-
(2000)
Nat Genet
, vol.26
, pp. 207-210
-
-
Delettre, C.1
Lenaers, G.2
Griffoin, J.M.3
Gigarel, N.4
Lorenzo, C.5
-
79
-
-
84862282562
-
Mitochondrial stress signaling HTRA2 and Parkinsońs disease
-
doi:10.1155/2012/607929
-
Desideri E, Martins M (2012) Mitochondrial stress signaling HTRA2 and Parkinsońs disease. Int J Cell Biol 2012: 607929. doi: 10. 1155/2012/607929.
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 607929
-
-
Desideri, E.1
Martins, M.2
-
81
-
-
33746620461
-
(De)constructing mitochondria: what for?
-
Dimmer KS, Scorrano L (2006) (De)constructing mitochondria: what for? Physiol 21: 233-241.
-
(2006)
Physiol
, vol.21
, pp. 233-241
-
-
Dimmer, K.S.1
Scorrano, L.2
-
82
-
-
75849118659
-
Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation
-
Dölle C, Niere M, Lohndal E, Ziegler M (2010) Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation. Cell Mol Life Sci 67: 433-443.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 433-443
-
-
Dölle, C.1
Niere, M.2
Lohndal, E.3
Ziegler, M.4
-
83
-
-
0034875011
-
Age-related changes in the autophagic proteolysis of rat isolated liver cells: effects of antiaging dietary restrictions
-
Donati A, Cavallini G, Paradiso C, Vittorini S, Pollera M, Gori Z, Bergamini E (2001) Age-related changes in the autophagic proteolysis of rat isolated liver cells: effects of antiaging dietary restrictions. J Gerontol A Biol Sci Med Sci 56: B375-B383.
-
(2001)
J Gerontol A Biol Sci Med Sci
, vol.56
-
-
Donati, A.1
Cavallini, G.2
Paradiso, C.3
Vittorini, S.4
Pollera, M.5
Gori, Z.6
Bergamini, E.7
-
85
-
-
67649814648
-
Heterogeneity of nervous system mitochondria: location, location, location
-
Dubinsky JM (2009) Heterogeneity of nervous system mitochondria: location, location, location. Exp Neurol 218(2): 293-307.
-
(2009)
Exp Neurol
, vol.218
, Issue.2
, pp. 293-307
-
-
Dubinsky, J.M.1
-
86
-
-
84870670254
-
Mitochondrial membranes in brain ageing and neurodegeneration
-
Eckmann J, Eckert SH, Leuner K, Müller WE, Eckert GP (2013) Mitochondrial membranes in brain ageing and neurodegeneration. Int J Biochem Cell Biol 45(1): 76-80.
-
(2013)
Int J Biochem Cell Biol
, vol.45
, Issue.1
, pp. 76-80
-
-
Eckmann, J.1
Eckert, S.H.2
Leuner, K.3
Müller, W.E.4
Eckert, G.P.5
-
87
-
-
78649908644
-
Life-long caloric restriction elicits pronounced protection of the aged myocardium: A role for AMPK
-
Edwards AG, Donato AJ, Lesniewski LA, Gioscia RA, Seals DR, Moore RL (2010) Life-long caloric restriction elicits pronounced protection of the aged myocardium: A role for AMPK. Mech Ageing Devel 131: 739-742.
-
(2010)
Mech Ageing Devel
, vol.131
, pp. 739-742
-
-
Edwards, A.G.1
Donato, A.J.2
Lesniewski, L.A.3
Gioscia, R.A.4
Seals, D.R.5
Moore, R.L.6
-
88
-
-
13244277942
-
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life
-
Elchuri S, Oberley TD, Qi W et al (2005) CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 24: 367-380.
-
(2005)
Oncogene
, vol.24
, pp. 367-380
-
-
Elchuri, S.1
Oberley, T.D.2
Qi, W.3
-
89
-
-
0029689984
-
Contractile-induced mitochondrial biogenesis in skeletal muscle
-
Essing DA (1996) Contractile-induced mitochondrial biogenesis in skeletal muscle. Exerc Sports Sci Rev 24: 289-319.
-
(1996)
Exerc Sports Sci Rev
, vol.24
, pp. 289-319
-
-
Essing, D.A.1
-
90
-
-
39449118273
-
Exercise training promotes SIRT1 activity in aged rats
-
Ferrara N, Rinaldi B, Corbi G, Conti V, Stiuso P, Boccuti S, Rengo G, Rossi F, Filippelli A (2008) Exercise training promotes SIRT1 activity in aged rats. Rejuv Res 11(1): 139-150.
-
(2008)
Rejuv Res
, vol.11
, Issue.1
, pp. 139-150
-
-
Ferrara, N.1
Rinaldi, B.2
Corbi, G.3
Conti, V.4
Stiuso, P.5
Boccuti, S.6
Rengo, G.7
Rossi, F.8
Filippelli, A.9
-
92
-
-
84862884156
-
Mitochondrial quality control: an integrated network of pathways
-
Fischer F, Hamann A, Osiewacz HD (2012) Mitochondrial quality control: an integrated network of pathways. Trends Biochem Sci 37(7): 284-292.
-
(2012)
Trends Biochem Sci
, vol.37
, Issue.7
, pp. 284-292
-
-
Fischer, F.1
Hamann, A.2
Osiewacz, H.D.3
-
93
-
-
0036751954
-
Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases
-
Floyd RA, Hensley K (2002) Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging 23(5): 795-807.
-
(2002)
Neurobiol Aging
, vol.23
, Issue.5
, pp. 795-807
-
-
Floyd, R.A.1
Hensley, K.2
-
94
-
-
0029978498
-
Age-related losses of cognitive function and motor skills in mice are associated with oxidative protein damage in the brain
-
Forster MJ, Dubey A, Dawson KM, Stutts WA, Lal H, Sohal RS (1996) Age-related losses of cognitive function and motor skills in mice are associated with oxidative protein damage in the brain. Proc Natl Acad Sci U S A 93: 4765-4769.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 4765-4769
-
-
Forster, M.J.1
Dubey, A.2
Dawson, K.M.3
Stutts, W.A.4
Lal, H.5
Sohal, R.S.6
-
95
-
-
8144229685
-
Deletion of p66shc gene protects against age-related endothelial dysfunction
-
Francia P, Delli Gatti C, Bachschmid M, Martin-Padura I, Savoia C, Migliaccio E, Pelicci PG, Schiavoni M, Luscher TF, Volpe M, Cosentino F (2004) Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation 110: 2889-2895.
-
(2004)
Circulation
, vol.110
, pp. 2889-2895
-
-
Francia, P.1
Delli Gatti, C.2
Bachschmid, M.3
Martin-Padura, I.4
Savoia, C.5
Migliaccio, E.6
Pelicci, P.G.7
Schiavoni, M.8
Luscher, T.F.9
Volpe, M.10
Cosentino, F.11
-
96
-
-
84867578930
-
Mitochondria, oxidative stress and neurodegeneration
-
Frederico A, Cardaioli E, DaPozzo P, Formichi P, Gallus GN, Radi E (2012) Mitochondria, oxidative stress and neurodegeneration. J Neurol Sci 322: 254-262.
-
(2012)
J Neurol Sci
, vol.322
, pp. 254-262
-
-
Frederico, A.1
Cardaioli, E.2
DaPozzo, P.3
Formichi, P.4
Gallus, G.N.5
Radi, E.6
-
97
-
-
75949130828
-
PINK1/PARKIN-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S, Holmström KM, Skujat D, Fiesel FC, Rothfuss OC (2010) PINK1/PARKIN-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nature Cell Biol 12(2): 119-131.
-
(2010)
Nature Cell Biol
, vol.12
, Issue.2
, pp. 119-131
-
-
Geisler, S.1
Holmström, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
-
98
-
-
26944442371
-
Improvement of memory for context by inhibition of caspase-1 in aged rats
-
Gemma C, Fister M, Hudson C, Bickford PC (2005) Improvement of memory for context by inhibition of caspase-1 in aged rats. Eur J Neurosci 22: 1751-1756.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 1751-1756
-
-
Gemma, C.1
Fister, M.2
Hudson, C.3
Bickford, P.C.4
-
99
-
-
34247259630
-
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1a
-
Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P (2007) Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1a. EMBO J 26: 1913-1923.
-
(2007)
EMBO J
, vol.26
, pp. 1913-1923
-
-
Gerhart-Hines, Z.1
Rodgers, J.T.2
Bare, O.3
Lerin, C.4
Kim, S.H.5
Mostoslavsky, R.6
Alt, F.W.7
Wu, Z.8
Puigserver, P.9
-
100
-
-
77950127881
-
SIRT1 negatively regulates the mammalian target of rapamycin
-
Ghosh HS, McBurney M, Robbins PD (2010) SIRT1 negatively regulates the mammalian target of rapamycin. PLoS One 5(2): e9199.
-
(2010)
PLoS One
, vol.5
, Issue.2
-
-
Ghosh, H.S.1
McBurney, M.2
Robbins, P.D.3
-
101
-
-
68949156130
-
Mitochondrial DNA nucleoids determine mitochondrial genetics and dysfunction
-
Gilkerson RW (2009) Mitochondrial DNA nucleoids determine mitochondrial genetics and dysfunction. Int J Biochem Cell Biol 41: 1899-1906.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1899-1906
-
-
Gilkerson, R.W.1
-
102
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio M, Migliaccio E, Orsini F, Paolucci D, Moroni M, Contursi C, Pelliccia G, Luzi L, Minucci S, Marcaccio M, Pinton P, Rizzuto R, Bernardi P, Paolucci F, Pelicci PG (2005) Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 122: 221-233.
-
(2005)
Cell
, vol.122
, pp. 221-233
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
Pinton, P.11
Rizzuto, R.12
Bernardi, P.13
Paolucci, F.14
Pelicci, P.G.15
-
103
-
-
68949148655
-
Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology
-
Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41: 1837-1845.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1837-1845
-
-
Gnaiger, E.1
-
104
-
-
41149105722
-
Mitochondria in cancer cells: what is so special about them?
-
Gogvadze V, Orrenius S, Zhivotovsky B (2008) Mitochondria in cancer cells: what is so special about them? Trends Cell Biol 18(4): 165-173.
-
(2008)
Trends Cell Biol
, vol.18
, Issue.4
, pp. 165-173
-
-
Gogvadze, V.1
Orrenius, S.2
Zhivotovsky, B.3
-
105
-
-
50949115617
-
High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy
-
Gomes LC, Scorrano L (2008) High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy. Biochim Biophys Acta 1777: 860-866.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 860-866
-
-
Gomes, L.C.1
Scorrano, L.2
-
106
-
-
79955623510
-
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
-
Gomes LC, Di Benedetto G, Scorrano L (2011) During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. Nature Cell Biol 13(5): 589-600.
-
(2011)
Nature Cell Biol
, vol.13
, Issue.5
, pp. 589-600
-
-
Gomes, L.C.1
Di Benedetto, G.2
Scorrano, L.3
-
107
-
-
33751409127
-
Cardiac mitochondrial connexin 43 regulates apoptosis
-
Goubaeva F, Mikami M, Giardina S, Ding B, Abe J, Yang J (2007) Cardiac mitochondrial connexin 43 regulates apoptosis. Biochem Biophys Res Commun 352: 97-103.
-
(2007)
Biochem Biophys Res Commun
, vol.352
, pp. 97-103
-
-
Goubaeva, F.1
Mikami, M.2
Giardina, S.3
Ding, B.4
Abe, J.5
Yang, J.6
-
108
-
-
80055008140
-
Hydrogen peroxide: a Jekyll and Hyde signalling molecule
-
doi: 10. 1038/cddis. 2011. 96
-
Gough DR, Cotter TG (2011) Hydrogen peroxide: a Jekyll and Hyde signalling molecule. Cell Death Dis 2: e213. doi: 10. 1038/cddis. 2011. 96.
-
(2011)
Cell Death Dis
, vol.2
-
-
Gough, D.R.1
Cotter, T.G.2
-
109
-
-
79957923566
-
Mitochondria regulate autophagy by conserved signalling pathways
-
Graef M, Nunnari J (2011) Mitochondria regulate autophagy by conserved signalling pathways. EMBO J 30: 2101-2114.
-
(2011)
EMBO J
, vol.30
, pp. 2101-2114
-
-
Graef, M.1
Nunnari, J.2
-
110
-
-
0035403165
-
Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart
-
Gredilla R, Sanz A, Lopez-Torres M, Barja G (2001) Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart. FASEB J 15: 1589-1591.
-
(2001)
FASEB J
, vol.15
, pp. 1589-1591
-
-
Gredilla, R.1
Sanz, A.2
Lopez-Torres, M.3
Barja, G.4
-
111
-
-
33747877758
-
Mitochondrial free radical generation and lifespan control in the fungal aging model Podosopora anserina
-
Gredilla R, Grief J, Osiewacz HD (2006) Mitochondrial free radical generation and lifespan control in the fungal aging model Podosopora anserina. Exp Gerontol 41: 439-447.
-
(2006)
Exp Gerontol
, vol.41
, pp. 439-447
-
-
Gredilla, R.1
Grief, J.2
Osiewacz, H.D.3
-
112
-
-
77953348161
-
Mitochondrial DNA repair and association with aging -An update
-
Gredilla R, Bohr VA, Stevsner T (2010) Mitochondrial DNA repair and association with aging -An update. Exp Gerontol 45(7-8): 478-488.
-
(2010)
Exp Gerontol
, vol.45
, Issue.7-8
, pp. 478-488
-
-
Gredilla, R.1
Bohr, V.A.2
Stevsner, T.3
-
113
-
-
34547946356
-
Differential proteomic profiling of mitochondria from Podospora anserina, rat and human reveals distinct patterns of age-related oxidative changes
-
Groebe K, Krause F, Kunstmann B, Unterluggauer H et al (2007) Differential proteomic profiling of mitochondria from Podospora anserina, rat and human reveals distinct patterns of age-related oxidative changes. Exptl Gerontol 42: 887-898.
-
(2007)
Exptl Gerontol
, vol.42
, pp. 887-898
-
-
Groebe, K.1
Krause, F.2
Kunstmann, B.3
Unterluggauer, H.4
-
114
-
-
4344677922
-
Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and "aggresomes" during oxidative stress, aging, and disease
-
Grune T, Jung T, Merker K, Davies KJ (2004) Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and "aggresomes" during oxidative stress, aging, and disease. Int J Biochem Cell Biol 36: 2519-2530.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2519-2530
-
-
Grune, T.1
Jung, T.2
Merker, K.3
Davies, K.J.4
-
115
-
-
33845868198
-
Sirtuins as potential targets for metabolic syndrome
-
Guarente L (2006) Sirtuins as potential targets for metabolic syndrome. Nature 444: 868-874.
-
(2006)
Nature
, vol.444
, pp. 868-874
-
-
Guarente, L.1
-
116
-
-
38649132337
-
Mitochondria-a nexus for aging, calorie restriction, and sirtuins?
-
Guarente L (2008) Mitochondria-a nexus for aging, calorie restriction, and sirtuins? Cell 132: 171-176.
-
(2008)
Cell
, vol.132
, pp. 171-176
-
-
Guarente, L.1
-
117
-
-
84899547370
-
Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors
-
Guglielmotto M, Giliberto L, Tamagno E, Tabaton M (2010) Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors. Front Aging Neurosci 2(3): 1-8.
-
(2010)
Front Aging Neurosci
, vol.2
, Issue.3
, pp. 1-8
-
-
Guglielmotto, M.1
Giliberto, L.2
Tamagno, E.3
Tabaton, M.4
-
118
-
-
73349088166
-
Tap63 induces senescence and suppresses tumorigenesis in vivo
-
Guo X, Keyes WM, Papazoglu C, Zuber J, Li W, Lowe SW, Vogel H, Mills AA (2009) Tap63 induces senescence and suppresses tumorigenesis in vivo. Nature Cell Biol 11: 1451-1457.
-
(2009)
Nature Cell Biol
, vol.11
, pp. 1451-1457
-
-
Guo, X.1
Keyes, W.M.2
Papazoglu, C.3
Zuber, J.4
Li, W.5
Lowe, S.W.6
Vogel, H.7
Mills, A.A.8
-
120
-
-
79952266729
-
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
-
Hafner AV, Dai J, Gomes AP, Xiao CY, Palmeira CM, Rosenzweig A, Sinclair DA (2010) Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging (Albany NY) 2(12): 914-923.
-
(2010)
Aging (Albany NY)
, vol.2
, Issue.12
, pp. 914-923
-
-
Hafner, A.V.1
Dai, J.2
Gomes, A.P.3
Xiao, C.Y.4
Palmeira, C.M.5
Rosenzweig, A.6
Sinclair, D.A.7
-
121
-
-
0030915483
-
Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase
-
Hagen TM, Yowe DL, Bartholomew JC, Wehr CM, Do KL, Park J-Y, Ames BN (1997) Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci USA 94: 3064-3069.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3064-3069
-
-
Hagen, T.M.1
Yowe, D.L.2
Bartholomew, J.C.3
Wehr, C.M.4
Do, K.L.5
Park, J.-Y.6
Ames, B.N.7
-
122
-
-
33746207799
-
Mitochondria and preconditioning: a connexin connection?
-
Halestrap AP (2006) Mitochondria and preconditioning: a connexin connection? Circ Res 99: 10-12.
-
(2006)
Circ Res
, vol.99
, pp. 10-12
-
-
Halestrap, A.P.1
-
123
-
-
33748414614
-
Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart
-
Hamacher-Brady A, Brady NR, Gottlieb RA, Gustafsson AB (2006) Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart. Autophagy 2: 307-309.
-
(2006)
Autophagy
, vol.2
, pp. 307-309
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Gottlieb, R.A.3
Gustafsson, A.B.4
-
124
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
Hamasaki M, Furuta N, Matsuda A, Nezu A, Yamamoto A et al (2013) Autophagosomes form at ER-mitochondria contact sites. Nature 495: 389-395.
-
(2013)
Nature
, vol.495
, pp. 389-395
-
-
Hamasaki, M.1
Furuta, N.2
Matsuda, A.3
Nezu, A.4
Yamamoto, A.5
-
126
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11: 298-300.
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
127
-
-
0015319592
-
The biologic clock: the mitochondria?
-
Harman D (1972) The biologic clock: the mitochondria? J Am GerSoc 20(4): 145-147.
-
(1972)
J Am GerSoc
, vol.20
, Issue.4
, pp. 145-147
-
-
Harman, D.1
-
128
-
-
33744478401
-
Free radical theory of aging: an update: increasing the functional life span
-
Harman D (2006) Free radical theory of aging: an update: increasing the functional life span. Ann N Y Acad Sci 1067: 10-21.
-
(2006)
Ann N Y Acad Sci
, vol.1067
, pp. 10-21
-
-
Harman, D.1
-
129
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K et al (2009) Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460(7253): 392-395.
-
(2009)
Nature
, vol.460
, Issue.7253
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
-
130
-
-
51649126499
-
Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor A in mice
-
Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M et al (2008) Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor A in mice. J Neurosci 28(34): 8624-8634.
-
(2008)
J Neurosci
, vol.28
, Issue.34
, pp. 8624-8634
-
-
Hayashi, Y.1
Yoshida, M.2
Yamato, M.3
Ide, T.4
Wu, Z.5
Ochi-Shindou, M.6
-
131
-
-
34249981756
-
A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: the benefit depends on the type of training performed
-
Haykowsky MJ, Liang Y, Pechter D, Jones LW, McAlister FA, Clark AM (2007) A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: the benefit depends on the type of training performed. J Am Coll Cardiol 49: 2329-2336.
-
(2007)
J Am Coll Cardiol
, vol.49
, pp. 2329-2336
-
-
Haykowsky, M.J.1
Liang, Y.2
Pechter, D.3
Jones, L.W.4
McAlister, F.A.5
Clark, A.M.6
-
132
-
-
70549089770
-
Cellular and nuclear degradation during apoptosis
-
He B, Lu N, Zhou Z (2009) Cellular and nuclear degradation during apoptosis. Curr Op Cell Biol 21: 900-912.
-
(2009)
Curr Op Cell Biol
, vol.21
, pp. 900-912
-
-
He, B.1
Lu, N.2
Zhou, Z.3
-
133
-
-
0034912378
-
Effect of age on mitochondrial and nuclear DNA oxidative damage in the heart and brain throughout the life-span of the rat
-
Herrero A, Barja G (2001) Effect of age on mitochondrial and nuclear DNA oxidative damage in the heart and brain throughout the life-span of the rat. J Am Aging Assoc 24: 45-50.
-
(2001)
J Am Aging Assoc
, vol.24
, pp. 45-50
-
-
Herrero, A.1
Barja, G.2
-
134
-
-
34250163244
-
Yeast apurinic / apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
-
Ho R, Rachek LI, Xu Y, Kelley MR, LeDoux SP, Wilson GL (2007) Yeast apurinic / apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress. J Neurochem 102: 13-24.
-
(2007)
J Neurochem
, vol.102
, pp. 13-24
-
-
Ho, R.1
Rachek, L.I.2
Xu, Y.3
Kelley, M.R.4
LeDoux, S.P.5
Wilson, G.L.6
-
135
-
-
63349106641
-
Bioenergetics and permeability transition pore opening in heart subsarcolemmal and interfibrillar mitochondria: effects of aging and lifelong calorie restriction
-
Hofer T, Servais S, Seo AY, Marzetti E, Hiona A, Upadhyay SJ, Wohlgemutz SE, Leeuwenburgh C (2009) Bioenergetics and permeability transition pore opening in heart subsarcolemmal and interfibrillar mitochondria: effects of aging and lifelong calorie restriction. Mech Ageing Dev 130: 297-307.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 297-307
-
-
Hofer, T.1
Servais, S.2
Seo, A.Y.3
Marzetti, E.4
Hiona, A.5
Upadhyay, S.J.6
Wohlgemutz, S.E.7
Leeuwenburgh, C.8
-
136
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, Cervera P, Le Bouc Y (2003) IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421: 182-187.
-
(2003)
Nature
, vol.421
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Geloen, A.5
Even, P.C.6
Cervera, P.7
Le Bouc, Y.8
-
137
-
-
0037230261
-
Plasticity of skeletal muscle mitochondria: structure and function
-
Hoppeler H, Flück M (2003) Plasticity of skeletal muscle mitochondria: structure and function. Med Sci Sports Exerc 35(1): 95-104.
-
(2003)
Med Sci Sports Exerc
, vol.35
, Issue.1
, pp. 95-104
-
-
Hoppeler, H.1
Flück, M.2
-
138
-
-
0015865749
-
The ultrastructure of the normal human skeletal muscle. A morphometric analysis on untrained men, women and well-trained orienteers
-
Hoppeler H, Lüthi P, Claassen H, Weibel ER, Howald H (1973) The ultrastructure of the normal human skeletal muscle. A morphometric analysis on untrained men, women and well-trained orienteers. Pflügers Arch 344: 217-232.
-
(1973)
Pflügers Arch
, vol.344
, pp. 217-232
-
-
Hoppeler, H.1
Lüthi, P.2
Claassen, H.3
Weibel, E.R.4
Howald, H.5
-
139
-
-
85044703856
-
No reduction of metabolic rate in food restricted Caenorhabditis elegans
-
Houthoofd K, Braeckman BP, Lenaerts I, Brys K, De Vreese A, van Eygen S, Vanfleteren JR (2002a) No reduction of metabolic rate in food restricted Caenorhabditis elegans. Exp Gerontol 37(12): 1359-1369.
-
(2002)
Exp Gerontol
, vol.37
, Issue.12
, pp. 1359-1369
-
-
Houthoofd, K.1
Braeckman, B.P.2
Lenaerts, I.3
Brys, K.4
De Vreese, A.5
van Eygen, S.6
Vanfleteren, J.R.7
-
140
-
-
0036975161
-
Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans
-
Houthoofd K, Braeckman BP, Lenaerts I et al (2002b) Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans. Exp Gerontol 37(12): 1371-1378.
-
(2002)
Exp Gerontol
, vol.37
, Issue.12
, pp. 1371-1378
-
-
Houthoofd, K.1
Braeckman, B.P.2
Lenaerts, I.3
-
141
-
-
25644432048
-
Dietary restriction in the nematode Caenorhabditis elegans
-
Houthoofd K, Johnson TE, Vanfleteren JR (2005) Dietary restriction in the nematode Caenorhabditis elegans. J Gerontol A 60(9): 1125-1131.
-
(2005)
J Gerontol A
, vol.60
, Issue.9
, pp. 1125-1131
-
-
Houthoofd, K.1
Johnson, T.E.2
Vanfleteren, J.R.3
-
142
-
-
33846189759
-
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-ß, and Bcl-2
-
Høyer-Hansen M, Bastholm L, Szymiaroski P, Campanella M, Szabadakai G et al (2007) Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-ß, and Bcl-2. Mol Cell 25: 193-205.
-
(2007)
Mol Cell
, vol.25
, pp. 193-205
-
-
Høyer-Hansen, M.1
Bastholm, L.2
Szymiaroski, P.3
Campanella, M.4
Szabadakai, G.5
-
143
-
-
40149092156
-
Sirt1 protects the heart from aging and stress
-
Hsu CP, Odewale I, Alcendor RR, Sadoshima J (2008) Sirt1 protects the heart from aging and stress. Biol Chem 389(3): 221-231.
-
(2008)
Biol Chem
, vol.389
, Issue.3
, pp. 221-231
-
-
Hsu, C.P.1
Odewale, I.2
Alcendor, R.R.3
Sadoshima, J.4
-
144
-
-
34547138950
-
Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis
-
Hua G, Zhang Q, Fan Z (2007) Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis. J Biol Chem 282: 20553-20560.
-
(2007)
J Biol Chem
, vol.282
, pp. 20553-20560
-
-
Hua, G.1
Zhang, Q.2
Fan, Z.3
-
145
-
-
2942563805
-
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
-
Hwangbo DS, Gersham B, Tu MP, Palmer M, Tatar M (2004) Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 429: 562-566.
-
(2004)
Nature
, vol.429
, pp. 562-566
-
-
Hwangbo, D.S.1
Gersham, B.2
Tu, M.P.3
Palmer, M.4
Tatar, M.5
-
146
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
Ishihara T, Hong M, Zhang B, Nakagawa Y, Lee MK, Trojanowski JQ, Lee VM (1999) Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron 24: 751-762.
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
Lee, V.M.7
-
147
-
-
68249087424
-
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
-
Ishihara N, Nomura M, Jofuku A, Kato H, Suzuki SO et al (2009) Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol 11: 958-966.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 958-966
-
-
Ishihara, N.1
Nomura, M.2
Jofuku, A.3
Kato, H.4
Suzuki, S.O.5
-
148
-
-
62349116477
-
The mitochondrial theory of aging: insight from transgenic and knockout mouse models
-
Jang YC, van Remmen H (2009) The mitochondrial theory of aging: insight from transgenic and knockout mouse models. Exp Gerontol 44(4): 256-260.
-
(2009)
Exp Gerontol
, vol.44
, Issue.4
, pp. 256-260
-
-
Jang, Y.C.1
van Remmen, H.2
-
149
-
-
18844444203
-
Morpho-dynamic changes of mitochondria during aging of human endothelial cells
-
Jendrach M, Pohl S, Vöth M, Kowald A, Hammerstein P, Bereiter-Hahn J (2005) Morpho-dynamic changes of mitochondria during aging of human endothelial cells. Mech Aging Dev 126: 813-821.
-
(2005)
Mech Aging Dev
, vol.126
, pp. 813-821
-
-
Jendrach, M.1
Pohl, S.2
Vöth, M.3
Kowald, A.4
Hammerstein, P.5
Bereiter-Hahn, J.6
-
150
-
-
53049099984
-
Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress
-
Jendrach M, Mai S, Pohl S, Vöth M, Bereiter-Hahn J (2008) Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress. Mitochondrion 8: 293-304.
-
(2008)
Mitochondrion
, vol.8
, pp. 293-304
-
-
Jendrach, M.1
Mai, S.2
Pohl, S.3
Vöth, M.4
Bereiter-Hahn, J.5
-
151
-
-
69049090808
-
Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia
-
Ježek P, Plecitá-Hlavatá L (2009) Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia. Int J Biochem Cell Biol 41: 1790-1804.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1790-1804
-
-
Ježek, P.1
Plecitá-Hlavatá, L.2
-
152
-
-
0005280130
-
Exercise-induced oxidative stress in the heart
-
C. K. Sen, L. Packer, O. Hanninen, C. K. Sen, L. Packer, and O. Hanninens (Eds.), Basel: Elsevier BV
-
Ji L (2000) Exercise-induced oxidative stress in the heart. In: Sen CK, Packer L, Hanninen O, Sen CK, Packer L, Hanninens O (eds) Handbook of oxidants and antioxidants in exercise. Elsevier BV, Basel, pp 689-712.
-
(2000)
Handbook of Oxidants and Antioxidants in Exercise
, pp. 689-712
-
-
Ji, L.1
-
153
-
-
34250164631
-
Elevated hydrostatic pressure triggers mitochondrial fission and decreases cellular ATP in differentiated RGC-5 cells
-
Ju W-K, Quan Liu Q, Kim KJ, Crowston JG, Lindsey JD, Agarwal N, Ellisman MH, Perkins GA, Weinreb RN (2007) Elevated hydrostatic pressure triggers mitochondrial fission and decreases cellular ATP in differentiated RGC-5 cells. Invest Ophthalmol Visual Sci 48(5): 2145-2151.
-
(2007)
Invest Ophthalmol Visual Sci
, vol.48
, Issue.5
, pp. 2145-2151
-
-
Ju, W.-K.1
Quan Liu, Q.2
Kim, K.J.3
Crowston, J.G.4
Lindsey, J.D.5
Agarwal, N.6
Ellisman, M.H.7
Perkins, G.A.8
Weinreb, R.N.9
-
154
-
-
84862605918
-
Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage
-
Kageyama Y, Zhang Z, Roda R, Fukaya M, Wkabayashi J et al (2012) Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage. J Cell Biol 197(4): 535-551.
-
(2012)
J Cell Biol
, vol.197
, Issue.4
, pp. 535-551
-
-
Kageyama, Y.1
Zhang, Z.2
Roda, R.3
Fukaya, M.4
Wkabayashi, J.5
-
155
-
-
0008235624
-
Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats
-
Kajstura J, Cheng W, Sarangarajan R, Li P, Li B, Nitahara JA, Chapnick S, Reiss K, Olivetti G, Anversa P (1996) Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol 271: H1215-H1228.
-
(1996)
Am J Physiol
, vol.271
-
-
Kajstura, J.1
Cheng, W.2
Sarangarajan, R.3
Li, P.4
Li, B.5
Nitahara, J.A.6
Chapnick, S.7
Reiss, K.8
Olivetti, G.9
Anversa, P.10
-
156
-
-
14644422657
-
Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer
-
Kang D, Hamasaki N (2005) Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer. Curr Med Chem 12: 429-441.
-
(2005)
Curr Med Chem
, vol.12
, pp. 429-441
-
-
Kang, D.1
Hamasaki, N.2
-
157
-
-
7644237446
-
Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA
-
Kanki T, Ohgaki K, Gaspari M, Gustafsson CM, Fukuoh A, Sasaki N, Hamasaki N, Kang D (2004) Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA. Mol Cell Biol 24: 9823-9834.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9823-9834
-
-
Kanki, T.1
Ohgaki, K.2
Gaspari, M.3
Gustafsson, C.M.4
Fukuoh, A.5
Sasaki, N.6
Hamasaki, N.7
Kang, D.8
-
158
-
-
0019888393
-
Multiple autopoly(ADP-ribosyl)ation of rat liver poly(ADP-ribose) synthetase. Mode of modification and properties of automodified synthetase
-
Kawaichi M, Ueda K, Hayaishi O (1981) Multiple autopoly(ADP-ribosyl)ation of rat liver poly(ADP-ribose) synthetase. Mode of modification and properties of automodified synthetase. J Biol Chem 256: 9483-9489.
-
(1981)
J Biol Chem
, vol.256
, pp. 9483-9489
-
-
Kawaichi, M.1
Ueda, K.2
Hayaishi, O.3
-
159
-
-
0035917440
-
A conserved regulatory system for aging
-
Kenyon C (2001) A conserved regulatory system for aging. Cell 105: 165-168.
-
(2001)
Cell
, vol.105
, pp. 165-168
-
-
Kenyon, C.1
-
160
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366: 461-464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
161
-
-
55349102294
-
Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer
-
Kiebish MA, Han X, Cheng H, Chuang JH, Seyfried TN (2008) Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer. J Lipid Res 49: 2545-2556.
-
(2008)
J Lipid Res
, vol.49
, pp. 2545-2556
-
-
Kiebish, M.A.1
Han, X.2
Cheng, H.3
Chuang, J.H.4
Seyfried, T.N.5
-
163
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim Y, Park J, Kim S, Song S, Kwon SK, Lee SH, Kitada T, Kim JM, Chung J (2008) PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem Biophys Res Commun 377: 975-980.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
Kim, S.3
Song, S.4
Kwon, S.K.5
Lee, S.H.6
Kitada, T.7
Kim, J.M.8
Chung, J.9
-
164
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh H, Lleonart ME, Gil J, Wang J, Dega P, Peters G, Martinez D, Carnero A, Beach D (2005) Glycolytic enzymes can modulate cellular life span. Cancer Res 65: 177-185.
-
(2005)
Cancer Res
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Dega, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
165
-
-
33645282296
-
Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy
-
Konhilas JP, Watson PA, Maass A, Boucek DM, Horn T, Stauffer BL, Luckey SW, Rosenberg P, Leinwand LA (2006) Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circ Res 98: 540-548.
-
(2006)
Circ Res
, vol.98
, pp. 540-548
-
-
Konhilas, J.P.1
Watson, P.A.2
Maass, A.3
Boucek, D.M.4
Horn, T.5
Stauffer, B.L.6
Luckey, S.W.7
Rosenberg, P.8
Leinwand, L.A.9
-
166
-
-
27744524523
-
On the relevance of mitochondrial fusions for the accumulation of mitochondrial deletion mutants: a modelling study
-
Kowald A, Jendrach M, Pohl S, Bereiter-Hahn J, Hammerstein P (2005) On the relevance of mitochondrial fusions for the accumulation of mitochondrial deletion mutants: a modelling study. Aging Cell 4: 273-283.
-
(2005)
Aging Cell
, vol.4
, pp. 273-283
-
-
Kowald, A.1
Jendrach, M.2
Pohl, S.3
Bereiter-Hahn, J.4
Hammerstein, P.5
-
167
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G, Galluzzi L, Brenner C (2007) Mitochondrial membrane permeabilization in cell death. Physiol Rev 87: 99-163.
-
(2007)
Physiol Rev
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
168
-
-
84858007124
-
The failure to extend lifespan via disruption of complex II is linked to preservation of dynamic control of energy metabolism
-
Kuang J, Ebert PR (2012) The failure to extend lifespan via disruption of complex II is linked to preservation of dynamic control of energy metabolism. Mitochondrion 12: 280-287.
-
(2012)
Mitochondrion
, vol.12
, pp. 280-287
-
-
Kuang, J.1
Ebert, P.R.2
-
169
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth GC, Hiona TD, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA et al (2005) Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309: 481-484.
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, T.D.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
-
170
-
-
80051972817
-
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA
-
Kukat C, Wurm CA, Spåhr H, Falkenberg M, Larsson N-G, Jakobs S (2011) Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA. PNAS 108(33): 13534-13539.
-
(2011)
Pnas
, vol.108
, Issue.33
, pp. 13534-13539
-
-
Kukat, C.1
Wurm, C.A.2
Spåhr, H.3
Falkenberg, M.4
Larsson, N.-G.5
Jakobs, S.6
-
171
-
-
84875472017
-
The role of free radicals in the aging brain and Parkinson's disease: convergence and parallelism
-
Kumar H, Lim H-W, More SV, Kim B-W, Koppula S et al (2012) The role of free radicals in the aging brain and Parkinson's disease: convergence and parallelism. Int J Mol Sci 13: 10478-10504.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 10478-10504
-
-
Kumar, H.1
Lim, H.-W.2
More, S.V.3
Kim, B.-W.4
Koppula, S.5
-
172
-
-
80052966447
-
Mitochondrial dynamics: a potential new therapeutic target for heart failure
-
Kuzmicic J, del Campo A, López-Crisosto C, Morales PE et al (2011) Mitochondrial dynamics: a potential new therapeutic target for heart failure. Rev Esp Cardiol 654(10): 916-923.
-
(2011)
Rev Esp Cardiol
, vol.654
, Issue.10
, pp. 916-923
-
-
Kuzmicic, J.1
del Campo, A.2
López-Crisosto, C.3
Morales, P.E.4
-
173
-
-
33845399894
-
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P et al (2006) Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1. Cell 127: 1109-1122.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
-
174
-
-
0036743518
-
A mutation in the ATP2 gene abrogates the age asymmetry between mother and daughter cells of the yeast Saccharomyces cerevisiae
-
Lai C-Y, Jaruga E, Borghouts C, Jazwinski SM (2002) A mutation in the ATP2 gene abrogates the age asymmetry between mother and daughter cells of the yeast Saccharomyces cerevisiae. Genetics 162: 73-87.
-
(2002)
Genetics
, vol.162
, pp. 73-87
-
-
Lai, C.-Y.1
Jaruga, E.2
Borghouts, C.3
Jazwinski, S.M.4
-
175
-
-
0032573178
-
The genetics of caloric restriction in Caenorhabditis elegans
-
Lakowski B, Hekimi S (1998) The genetics of caloric restriction in Caenorhabditis elegans. Proc Nat Acad Sci USA 95(22): 13091-13096.
-
(1998)
Proc Nat Acad Sci USA
, vol.95
, Issue.22
, pp. 13091-13096
-
-
Lakowski, B.1
Hekimi, S.2
-
176
-
-
77953627194
-
Somatic mitochondrial DNA mutations in mammalian aging
-
Larsson NG (2010). Somatic mitochondrial DNA mutations in mammalian aging. Annu Rev Biochem 79: 683-706.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 683-706
-
-
Larsson, N.G.1
-
177
-
-
66149090291
-
Exercise training inducibility of MnSOD protein expression and activity is retained while reducing prooxidant signaling in the heart of senescent rats
-
Lawler JM, Kwak HB, Kim JH, Suk MH (2009) Exercise training inducibility of MnSOD protein expression and activity is retained while reducing prooxidant signaling in the heart of senescent rats. Am J Physiol Regul Integr Comp Physiol 296(5): R1496-R1502.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.296
, Issue.5
-
-
Lawler, J.M.1
Kwak, H.B.2
Kim, J.H.3
Suk, M.H.4
-
178
-
-
0036420161
-
Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence
-
Lee H-C, Yin P-H, Chib C-W, Wei Y-H (2002a) Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J Biomed Sci 9: 517-526.
-
(2002)
J Biomed Sci
, vol.9
, pp. 517-526
-
-
Lee, H.-C.1
Yin, P.-H.2
Chib, C.-W.3
Wei, Y.-H.4
-
179
-
-
0037154311
-
Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty
-
Lee TM, Su SF, Chou TF, Lee YT, Tsai CH (2002b) Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty. Circulation 105(3): 334-340.
-
(2002)
Circulation
, vol.105
, Issue.3
, pp. 334-340
-
-
Lee, T.M.1
Su, S.F.2
Chou, T.F.3
Lee, Y.T.4
Tsai, C.H.5
-
180
-
-
34547958816
-
Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence
-
Lee S, Jeong S-Y, Lim W-C, Kim S, Park Y-Y et al (2007) Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence. J Biol Chem 282(31): 22977-22983.
-
(2007)
J Biol Chem
, vol.282
, Issue.31
, pp. 22977-22983
-
-
Lee, S.1
Jeong, S.-Y.2
Lim, W.-C.3
Kim, S.4
Park, Y.-Y.5
-
181
-
-
0036906665
-
Mitochondrial fusin in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins
-
Legros F, Lombès A, Frachon P, Rojo M (2002) Mitochondrial fusin in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell 13: 4343-4354.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 4343-4354
-
-
Legros, F.1
Lombès, A.2
Frachon, P.3
Rojo, M.4
-
182
-
-
4344573135
-
Insulin-like growth factor-I (IGF-I) regulates glucose-induced mitochondrial depolarization and apoptosis in human neuroblastoma
-
Leinninger GM, Russell JW, van Golen CM, Berent A, Feldman EL (2004) Insulin-like growth factor-I (IGF-I) regulates glucose-induced mitochondrial depolarization and apoptosis in human neuroblastoma. Cell Death Differ 11: 885-896.
-
(2004)
Cell Death Differ
, vol.11
, pp. 885-896
-
-
Leinninger, G.M.1
Russell, J.W.2
van Golen, C.M.3
Berent, A.4
Feldman, E.L.5
-
183
-
-
33746881744
-
Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1
-
Leinninger GM, Backus C, WSastry AM, Yi Y-B, Wang C-W, Feldman EL (2006) Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiol Dis 23(1): 11-22.
-
(2006)
Neurobiol Dis
, vol.23
, Issue.1
, pp. 11-22
-
-
Leinninger, G.M.1
Backus, C.2
WSastry, A.M.3
Yi, Y.-B.4
Wang, C.-W.5
Feldman, E.L.6
-
184
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G (2008) Autophagy in the pathogenesis of disease. Cell 132: 27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
185
-
-
48249092267
-
Bcl-2 family members: dual regulators of apoptosis and autophagy
-
Levine B, Sinha S, Kroemer B (2008) Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 4(5): 600-606.
-
(2008)
Autophagy
, vol.4
, Issue.5
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, B.3
-
186
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC et al (1995) Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 11(4): 376-381.
-
(1995)
Nat Genet
, vol.11
, Issue.4
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melov, S.4
Ursell, P.C.5
-
187
-
-
10944269186
-
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
-
Li Z, Okamoto K-I, Hayashi Y, Sheng M (2004) The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119: 873-887.
-
(2004)
Cell
, vol.119
, pp. 873-887
-
-
Li, Z.1
Okamoto, K.-I.2
Hayashi, Y.3
Sheng, M.4
-
188
-
-
0037081814
-
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
-
Lin MT, Simon DK, Ahn CH, Kim LM, Beal MF (2002a) High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Hum Mol Genet 11: 133-145.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 133-145
-
-
Lin, M.T.1
Simon, D.K.2
Ahn, C.H.3
Kim, L.M.4
Beal, M.F.5
-
189
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L (2002b) Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418: 344-348.
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
190
-
-
0036402136
-
Reactive oxygen species stimulated human hepatoma cell proliferation via cross-talk between PI3-K/PKB and JNK signaling pathways
-
Liu SL, Lin X, Shi DY, Cheng J, Wu CQ, Zhang YD (2002) Reactive oxygen species stimulated human hepatoma cell proliferation via cross-talk between PI3-K/PKB and JNK signaling pathways. Arch Biochem Biophys 406(2): 173-182.
-
(2002)
Arch Biochem Biophys
, vol.406
, Issue.2
, pp. 173-182
-
-
Liu, S.L.1
Lin, X.2
Shi, D.Y.3
Cheng, J.4
Wu, C.Q.5
Zhang, Y.D.6
-
191
-
-
74549184412
-
The polarisome is required for segregation and retrograde transport of protein aggregates
-
Liu B, Larsson L, Caballero A, Hao X, Öling D, Grantham J, Nyström T (2009) The polarisome is required for segregation and retrograde transport of protein aggregates. Cell 140: 257-267.
-
(2009)
Cell
, vol.140
, pp. 257-267
-
-
Liu, B.1
Larsson, L.2
Caballero, A.3
Hao, X.4
Öling, D.5
Grantham, J.6
Nyström, T.7
-
192
-
-
57349140895
-
Linking sirtuins, IGF-1 signaling, and starvation
-
Longo VD (2009) Linking sirtuins, IGF-1 signaling, and starvation. Exp Gerontol 44: 70-74.
-
(2009)
Exp Gerontol
, vol.44
, pp. 70-74
-
-
Longo, V.D.1
-
193
-
-
0037470488
-
Evolutionary medicine: from dwarf model systems to healthy centenarians?
-
Longo VD, Finch CE (2003) Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 299: 1342-1346.
-
(2003)
Science
, vol.299
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
194
-
-
79958773159
-
Age-related alterations in mitochondrial physiological parameters and nitric oxide production in synaptic and non-synaptic brain cortex mitochondria
-
Lores-Arnaiz S, Bustamante J (2011) Age-related alterations in mitochondrial physiological parameters and nitric oxide production in synaptic and non-synaptic brain cortex mitochondria. Neurosci 188: 117-124.
-
(2011)
Neurosci
, vol.188
, pp. 117-124
-
-
Lores-Arnaiz, S.1
Bustamante, J.2
-
195
-
-
0033984570
-
Decreased base excision repair and increased helicase activity in Alzheimer's disease brain
-
Lovell MA, Xie C, Markesbery WR (2000) Decreased base excision repair and increased helicase activity in Alzheimer's disease brain. Brain Res 855: 116-123.
-
(2000)
Brain Res
, vol.855
, pp. 116-123
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
196
-
-
84865738522
-
Chronic exercise modifies age-related telomere dynamics in a tissue-specific fashion
-
Ludlow AT, Witkowski S, Marshall MR, Wang J, Lima LCJ, Guth LM et al (2012) Chronic exercise modifies age-related telomere dynamics in a tissue-specific fashion. J Gerontol A Biol Sci Med Sci 67(9): 911-926.
-
(2012)
J Gerontol A Biol Sci Med Sci
, vol.67
, Issue.9
, pp. 911-926
-
-
Ludlow, A.T.1
Witkowski, S.2
Marshall, M.R.3
Wang, J.4
Lima, L.C.J.5
Guth, L.M.6
-
197
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB (2005) Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120: 237-248.
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
Thompson, C.B.7
-
198
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M et al (2004) ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science 304: 448-452.
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
-
199
-
-
33745921507
-
Mitochondria at the synapse
-
Ly CV, Verstreken P (2006) Mitochondria at the synapse. Neuroscientist 12: 291-299.
-
(2006)
Neuroscientist
, vol.12
, pp. 291-299
-
-
Ly, C.V.1
Verstreken, P.2
-
200
-
-
46349099816
-
Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell
-
Lyamzaev KG, Nepryankhina OK, Saprunova VB, Bakeeva LE, Pletjushkina OY, Chernyak BV, Skulachev P (2008) Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell. Biochim Biophys Acta 1777: 817-825.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 817-825
-
-
Lyamzaev, K.G.1
Nepryankhina, O.K.2
Saprunova, V.B.3
Bakeeva, L.E.4
Pletjushkina, O.Y.5
Chernyak, B.V.6
Skulachev, P.7
-
201
-
-
78649907737
-
Aging impair myocardium-induced dilatation of coronary arterioles: role of hydrogen peroxide and angiotensin
-
Machii H, Saitoh S-I, Kaneshiro T, Takeishi Y (2010) Aging impair myocardium-induced dilatation of coronary arterioles: role of hydrogen peroxide and angiotensin. Mech Ageing Dev 131: 710-717.
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 710-717
-
-
Machii, H.1
Saitoh, S.-I.2
Kaneshiro, T.3
Takeishi, Y.4
-
202
-
-
84857858536
-
Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
-
Maday S, Wallace KE, Holzbaur ELF (2012) Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. J Cell Biol 196(4): 407-417.
-
(2012)
J Cell Biol
, vol.196
, Issue.4
, pp. 407-417
-
-
Maday, S.1
Wallace, K.E.2
Holzbaur, E.L.F.3
-
204
-
-
77951199668
-
Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1
-
Mai S, Klinkenberg M, Auburger G, Bereiter-Hahn J, Jendrach M (2010) Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1. J Cell Sci 123: 917-926.
-
(2010)
J Cell Sci
, vol.123
, pp. 917-926
-
-
Mai, S.1
Klinkenberg, M.2
Auburger, G.3
Bereiter-Hahn, J.4
Jendrach, M.5
-
205
-
-
84856492243
-
Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence life span
-
Mai S, Muster B, Bereiter-Hahn J, Jendrach M (2012) Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence life span. Autophagy 8(1): 47-62.
-
(2012)
Autophagy
, vol.8
, Issue.1
, pp. 47-62
-
-
Mai, S.1
Muster, B.2
Bereiter-Hahn, J.3
Jendrach, M.4
-
206
-
-
30944446045
-
Separate fusion of outer and inner mitochondrial membranes
-
Malka F, Guillery O, Cifuentes-Diaz C, Guillou E, Belenguer P, Lombès A, Rojo M (2005) Separate fusion of outer and inner mitochondrial membranes. EMBO Rep 6(9): 853-859.
-
(2005)
EMBO Rep
, vol.6
, Issue.9
, pp. 853-859
-
-
Malka, F.1
Guillery, O.2
Cifuentes-Diaz, C.3
Guillou, E.4
Belenguer, P.5
Lombès, A.6
Rojo, M.7
-
207
-
-
34347249232
-
Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy
-
Maloyan A, Gulick J, Glabe CG, Kayed R, Robbins J (2007) Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy. Proc Natl Acad Sci USA 104: 5995-6000.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5995-6000
-
-
Maloyan, A.1
Gulick, J.2
Glabe, C.G.3
Kayed, R.4
Robbins, J.5
-
208
-
-
33646152108
-
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
-
Manczak M, Anekonda TS, Henson E, Park BS, Quinn J, Reddy PH (2006) Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum Mol Genet 15: 1437-1449.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
210
-
-
34948873673
-
Merging mitochondria for neuronal survival
-
Manfredi G, Beal MF (2007) Merging mitochondria for neuronal survival. Nature Med 13(10): 1140-1141.
-
(2007)
Nature Med
, vol.13
, Issue.10
, pp. 1140-1141
-
-
Manfredi, G.1
Beal, M.F.2
-
211
-
-
29544446876
-
Skeletal muscle mitochondrial DNA content in exercising humans
-
Marcuello A, Gonzalez-Alonso J, Calbet JAL, Damsgaard R, López-Pérez D-S (2005) Skeletal muscle mitochondrial DNA content in exercising humans. J Appl Physiol 99: 1372-1377.
-
(2005)
J Appl Physiol
, vol.99
, pp. 1372-1377
-
-
Marcuello, A.1
Gonzalez-Alonso, J.2
Calbet, J.A.L.3
Damsgaard, R.4
López-Pérez, D.-S.5
-
212
-
-
0027282957
-
Dietary restriction and aging
-
Masoro EJ (1993) Dietary restriction and aging. J Am Geriatr Soc 41: 994-999.
-
(1993)
J Am Geriatr Soc
, vol.41
, pp. 994-999
-
-
Masoro, E.J.1
-
213
-
-
34147168105
-
Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
-
Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H et al (2007) Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 100: 914-922.
-
(2007)
Circ Res
, vol.100
, pp. 914-922
-
-
Matsui, Y.1
Takagi, H.2
Qu, X.3
Abdellatif, M.4
Sakoda, H.5
-
214
-
-
35549008884
-
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
-
Mattagajasingh I, Kim CS, Nagvi A, Yamamori T, Hoffman TA, Jung SB, DeRicco J, Kasuno K, Irani K (2007) SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase. Proc Natl Acad Sci USA 104: 14855-14860.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14855-14860
-
-
Mattagajasingh, I.1
Kim, C.S.2
Nagvi, A.3
Yamamori, T.4
Hoffman, T.A.5
Jung, S.B.6
DeRicco, J.7
Kasuno, K.8
Irani, K.9
-
215
-
-
0037434879
-
Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin
-
Mattenberger Y, James DI, Martinou JC (2003) Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin. FEBS Lett 538: 53-59.
-
(2003)
FEBS Lett
, vol.538
, pp. 53-59
-
-
Mattenberger, Y.1
James, D.I.2
Martinou, J.C.3
-
216
-
-
78149338997
-
Exercise training restores impaired dilator responses of cerebral arterioles during chronic exposure to nicotine
-
Mayhan WG, Arrick DM, Sun H, Patel KP (2010) Exercise training restores impaired dilator responses of cerebral arterioles during chronic exposure to nicotine. J Appl Physiol 109(4): 1109-1114.
-
(2010)
J Appl Physiol
, vol.109
, Issue.4
, pp. 1109-1114
-
-
Mayhan, W.G.1
Arrick, D.M.2
Sun, H.3
Patel, K.P.4
-
217
-
-
0037207475
-
The mammalian SIR2α protein has a role in embryogenesis and gametogenesis
-
McBurney MW, Yang X, Jardine K, Hixon M, Boekelheide K, Webb JR, Lansdorp PM, Lemieux M (2003) The mammalian SIR2α protein has a role in embryogenesis and gametogenesis. Mol Cell Biol 23: 38-54.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 38-54
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Hixon, M.4
Boekelheide, K.5
Webb, J.R.6
Lansdorp, P.M.7
Lemieux, M.8
-
218
-
-
33646807843
-
Tissue-specific deletion patterns of the mitochondrial lgenome with advancing age
-
Meissner C, Bruse P, Oehmichen M (2006) Tissue-specific deletion patterns of the mitochondrial lgenome with advancing age. Exp Gerontol 41: 518-524.
-
(2006)
Exp Gerontol
, vol.41
, pp. 518-524
-
-
Meissner, C.1
Bruse, P.2
Oehmichen, M.3
-
219
-
-
33748288148
-
Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress
-
Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress. Diabetes 55: 1642-1650.
-
(2006)
Diabetes
, vol.55
, pp. 1642-1650
-
-
Menini, S.1
Amadio, L.2
Oddi, G.3
Ricci, C.4
Pesce, C.5
Pugliese, F.6
-
220
-
-
26244456362
-
Could the low level of expression of the gene encoding skeletal muscle mitofusin-2 account for the metabolic inflexibility of obesity?
-
Mingrone G, Manco M, Calvani M, Castagneto M, Naon D, Zorzano A (2005) Could the low level of expression of the gene encoding skeletal muscle mitofusin-2 account for the metabolic inflexibility of obesity? Diabetologia 48: 2108-2114.
-
(2005)
Diabetologia
, vol.48
, pp. 2108-2114
-
-
Mingrone, G.1
Manco, M.2
Calvani, M.3
Castagneto, M.4
Naon, D.5
Zorzano, A.6
-
221
-
-
77949801029
-
Mitofusin 2 is necessary for transport of axonal mitochondria an interacts with the Miro/Milton complex
-
Misko A, Jiang S, Wegorzewska I, Milbrandt J, Baloh RH (2010) Mitofusin 2 is necessary for transport of axonal mitochondria an interacts with the Miro/Milton complex. J Neurosci 30(12): 4232-4240.
-
(2010)
J Neurosci
, vol.30
, Issue.12
, pp. 4232-4240
-
-
Misko, A.1
Jiang, S.2
Wegorzewska, I.3
Milbrandt, J.4
Baloh, R.H.5
-
222
-
-
74049102401
-
The efficiency of mitochondrial electron transport chain is increased in the long-lived S. cerevisiae
-
Mittal N, Babu M, Roy N (2009) The efficiency of mitochondrial electron transport chain is increased in the long-lived S. cerevisiae. Aging Cell 8: 643-653.
-
(2009)
Aging Cell
, vol.8
, pp. 643-653
-
-
Mittal, N.1
Babu, M.2
Roy, N.3
-
223
-
-
56849084137
-
Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model
-
Miwa S, Lawless C, von Zglinicki T (2008) Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model. Aging Cell 7: 920-923.
-
(2008)
Aging Cell
, vol.7
, pp. 920-923
-
-
Miwa, S.1
Lawless, C.2
von Zglinicki, T.3
-
224
-
-
32444443812
-
Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis
-
Miyoshi N, Oubrahim H, Chock PB, Stadtman ER (2006) Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. Proc Natl Acad Sci U S A 103(6): 1727-1731.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.6
, pp. 1727-1731
-
-
Miyoshi, N.1
Oubrahim, H.2
Chock, P.B.3
Stadtman, E.R.4
-
225
-
-
38049007502
-
Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
-
Mortusewicz O, Amé J-C, Schreiber V, Leonhardt H (2007) Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res 35(22): 7665-7675.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.22
, pp. 7665-7675
-
-
Mortusewicz, O.1
Amé, J.-C.2
Schreiber, V.3
Leonhardt, H.4
-
226
-
-
67650348459
-
Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function
-
Mouli KP, Twig G, Shirihai OS (2009) Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function. Biophys J 96: 3509-3518.
-
(2009)
Biophys J
, vol.96
, pp. 3509-3518
-
-
Mouli, K.P.1
Twig, G.2
Shirihai, O.S.3
-
227
-
-
4344716374
-
Death-associated protein3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death
-
Mukamel Z, Kimchi A (2004) Death-associated protein3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death. J Biol Chem 279: 36732-36738.
-
(2004)
J Biol Chem
, vol.279
, pp. 36732-36738
-
-
Mukamel, Z.1
Kimchi, A.2
-
228
-
-
79251599453
-
Overexpresson of PaParp encoding the poly(ADP-ribose) polymerase of Podospora anserina affects organismal aging
-
Müller-Ohldach M, Brust D, Hamann A, Osiewacz HD (2010) Overexpresson of PaParp encoding the poly(ADP-ribose) polymerase of Podospora anserina affects organismal aging. Mech Ageing Dev 132: 33-42.
-
(2010)
Mech Ageing Dev
, vol.132
, pp. 33-42
-
-
Müller-Ohldach, M.1
Brust, D.2
Hamann, A.3
Osiewacz, H.D.4
-
229
-
-
77955638748
-
Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells
-
doi:10.1371/journal.pone.0011910
-
Muster B, Kohl W, Wittig I, Strecker V, Joos F et al (2010) Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells. PLoS One 5(7): e11910. doi: 10. 1371/journal. pone. 0011910.
-
(2010)
PLoS One
, vol.5
, Issue.7
-
-
Muster, B.1
Kohl, W.2
Wittig, I.3
Strecker, V.4
Joos, F.5
-
230
-
-
80053226539
-
SIRT1 mediated acute cardioprotection
-
doi:10.1152/ajpheart.00294.2011
-
Nadtochiy S, Yao H, McBurney M, Gu W, Guarente L, Rahman I, Brookes P (2011) SIRT1 mediated acute cardioprotection. AJP Heart 301(4): H1506-H1512. doi: 10. 1152/ajpheart. 00294. 2011.
-
(2011)
AJP Heart
, vol.301
, Issue.4
-
-
Nadtochiy, S.1
Yao, H.2
McBurney, M.3
Gu, W.4
Guarente, L.5
Rahman, I.6
Brookes, P.7
-
231
-
-
0034881326
-
Inter-mitochondrial complementation: mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA
-
Nakada K, Inoue K, Ono T, Isobe K, Ogura A et al (2001) Inter-mitochondrial complementation: mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat Med 7: 934-940.
-
(2001)
Nat Med
, vol.7
, pp. 934-940
-
-
Nakada, K.1
Inoue, K.2
Ono, T.3
Isobe, K.4
Ogura, A.5
-
232
-
-
68949150810
-
Mitochondrial functional complementation in mitochondrial DNA-based diseases
-
Nakada K, Sato A, Hayashi J-I (2009) Mitochondrial functional complementation in mitochondrial DNA-based diseases. Int J Biochem Cell Biol 41: 1907-1913.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1907-1913
-
-
Nakada, K.1
Sato, A.2
Hayashi, J.-I.3
-
233
-
-
0037452461
-
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
Napoli C, Martin-Padura I, de Nigris F, Giorgio M, Mansueto G, Somma P, Condorelli M, Sica G, De Rosa G, Pelicci PG (2003) Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc Natl Acad Sci U S A 100: 2112-2116.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2112-2116
-
-
Napoli, C.1
Martin-Padura, I.2
de Nigris, F.3
Giorgio, M.4
Mansueto, G.5
Somma, P.6
Condorelli, M.7
Sica, G.8
De Rosa, G.9
Pelicci, P.G.10
-
234
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183: 795-803.
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
235
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate parkin
-
Narendra DP, Jin SM, Tanaka A, Suen D-F, Gautier CA, Shen J, Cookson MR, Youle RJ (2010) PINK1 is selectively stabilized on impaired mitochondria to activate parkin. PloS Biology 8(1): e100298.
-
(2010)
PloS Biology
, vol.8
, Issue.1
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.-F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
236
-
-
33847059997
-
The mitochondrial energy transduction system and the aging process
-
Navarro A, Boveris A (2007) The mitochondrial energy transduction system and the aging process. Am J Physiol Cell Physiol 292: C670-C686.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Navarro, A.1
Boveris, A.2
-
237
-
-
0036084827
-
Behavioral dysfunction, brain oxidative stress, and impaired mitochondrial electron transfer in aging mice
-
Navarro A, Sánchez Del Pino MJ, Gómez C, Peralta JL, Boveris A (2002) Behavioral dysfunction, brain oxidative stress, and impaired mitochondrial electron transfer in aging mice. Am J Physiol Regul Integr Comp Physiol 282: R985-R989.
-
(2002)
Am J Physiol Regul Integr Comp Physiol
, vol.282
-
-
Navarro, A.1
Sánchez Del Pino, M.J.2
Gómez, C.3
Peralta, J.L.4
Boveris, A.5
-
238
-
-
1342309919
-
Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer
-
Navarro A, Gomez C, López-Cepero JM, Boveris A (2004) Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer. Am J Physiol Reg Physiol 286(3): R505-R511.
-
(2004)
Am J Physiol Reg Physiol
, vol.286
, Issue.3
-
-
Navarro, A.1
Gomez, C.2
López-Cepero, J.M.3
Boveris, A.4
-
239
-
-
27144436412
-
Vitamin E at high doses improves survival, neurological performance, and brain mitochondrial function in aging male mice
-
Navarro A, Gómez C, Sánchez-Pino MJ, González H, Bández MJ, Boveris AD, Boveris A (2005) Vitamin E at high doses improves survival, neurological performance, and brain mitochondrial function in aging male mice. Am J Physiol Regul Integr Comp Physiol 289: R1329-R1399.
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.289
-
-
Navarro, A.1
Gómez, C.2
Sánchez-Pino, M.J.3
González, H.4
Bández, M.J.5
Boveris, A.D.6
Boveris, A.7
-
240
-
-
36549002757
-
Giant mitochondria do not fuse and exchange their contents with normal mitochondria
-
Navratil M, Terman A, Arriaga EA (2008) Giant mitochondria do not fuse and exchange their contents with normal mitochondria. Exp Cell Res 314: 164-172.
-
(2008)
Exp Cell Res
, vol.314
, pp. 164-172
-
-
Navratil, M.1
Terman, A.2
Arriaga, E.A.3
-
241
-
-
38349023008
-
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers
-
Neuspiel M, Schauss AC, Braschi E, Zunino R, Rippstein P, Rachubinski RA et al (2008) Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Curr Biol 18: 102-108.
-
(2008)
Curr Biol
, vol.18
, pp. 102-108
-
-
Neuspiel, M.1
Schauss, A.C.2
Braschi, E.3
Zunino, R.4
Rippstein, P.5
Rachubinski, R.A.6
-
242
-
-
79251478801
-
Obesity induces signs of premature cardiac aging in younger patients. The role of mitochondria
-
Niemann B, Chen Y, Teschner M, Li L, Silber R-E, Rohrbach S (2011) Obesity induces signs of premature cardiac aging in younger patients. The role of mitochondria. J Am Coll Cardiol 57(5): 578-585.
-
(2011)
J Am Coll Cardiol
, vol.57
, Issue.5
, pp. 578-585
-
-
Niemann, B.1
Chen, Y.2
Teschner, M.3
Li, L.4
Silber, R.-E.5
Rohrbach, S.6
-
243
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E et al (2005) Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310: 314-317.
-
(2005)
Science
, vol.310
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
Tedesco, L.6
Falcone, S.7
Valerio, A.8
Cantoni, O.9
Clementi, E.10
-
244
-
-
56349130742
-
Increased aerobic metabolism is essential for the beneficial effects of caloric restriction on yeast life span
-
Oliveira GA, Tahara EB, Gombert AK, Barros MH, Kowaltowski AJ (2008) Increased aerobic metabolism is essential for the beneficial effects of caloric restriction on yeast life span. J Bioenerg Biomembr 40: 381-388.
-
(2008)
J Bioenerg Biomembr
, vol.40
, pp. 381-388
-
-
Oliveira, G.A.1
Tahara, E.B.2
Gombert, A.K.3
Barros, M.H.4
Kowaltowski, A.J.5
-
245
-
-
77952236126
-
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury
-
Ong SB, Subrayan S, Lim SY, Yellon DM, Davidson SM, Hausenloy DJ (2010) Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury. Circulation 121: 2012-2022.
-
(2010)
Circulation
, vol.121
, pp. 2012-2022
-
-
Ong, S.B.1
Subrayan, S.2
Lim, S.Y.3
Yellon, D.M.4
Davidson, S.M.5
Hausenloy, D.J.6
-
246
-
-
40849147435
-
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking
-
Orr AL, Li S, Wang CE, Li H, Wang J, Rong J, Xu X, Mastroberardino PG, Greenamyre JT, Li XJ (2008) N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking. J Neurosci 28: 2783-2792.
-
(2008)
J Neurosci
, vol.28
, pp. 2783-2792
-
-
Orr, A.L.1
Li, S.2
Wang, C.E.3
Li, H.4
Wang, J.5
Rong, J.6
Xu, X.7
Mastroberardino, P.G.8
Greenamyre, J.T.9
Li, X.J.10
-
247
-
-
84859760175
-
Mitochondrial dynamics: functional link with apoptosis
-
doi:10.1155/2012/821676
-
Otera H, Mihara K (2012) Mitochondrial dynamics: functional link with apoptosis. Int J Cell Biol. doi: 10. 1155/2012/821676.
-
(2012)
Int J Cell Biol
-
-
Otera, H.1
Mihara, K.2
-
248
-
-
0030897739
-
Genetic and functional changes in mitochondria associated with aging
-
Ozawa T (1997) Genetic and functional changes in mitochondria associated with aging. Physiol Rev 77: 425-464.
-
(1997)
Physiol Rev
, vol.77
, pp. 425-464
-
-
Ozawa, T.1
-
249
-
-
6344256347
-
A new, potent Poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging
-
Pacher P, Vaslin A, Benkó R, Mabley JB, Liaudet L, Haskó G, Marton A, Bátkai S, Kollai M, Szabó C (2004) A new, potent Poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging. J Pharmacol Exptl Therap 311: 485-491.
-
(2004)
J Pharmacol Exptl Therap
, vol.311
, pp. 485-491
-
-
Pacher, P.1
Vaslin, A.2
Benkó, R.3
Mabley, J.B.4
Liaudet, L.5
Haskó, G.6
Marton, A.7
Bátkai, S.8
Kollai, M.9
Szabó, C.10
-
250
-
-
0017740356
-
Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle
-
Palmer JW, Tandler B, Hoppel CL (1977) Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle. J Biol Chem 252: 8731-8739.
-
(1977)
J Biol Chem
, vol.252
, pp. 8731-8739
-
-
Palmer, J.W.1
Tandler, B.2
Hoppel, C.L.3
-
251
-
-
78651329567
-
Some highlights of research on aging with invertebrates
-
Partridge L (2010) Some highlights of research on aging with invertebrates. Aging Cell 10(1): 5-9.
-
(2010)
Aging Cell
, vol.10
, Issue.1
, pp. 5-9
-
-
Partridge, L.1
-
252
-
-
79959450877
-
Mitochondrial DNA mutations in disease and aging
-
Park CB, Larsson N-G (2011) Mitochondrial DNA mutations in disease and aging. J Cell Biol 193(5): 809-818.
-
(2011)
J Cell Biol
, vol.193
, Issue.5
, pp. 809-818
-
-
Park, C.B.1
Larsson, N.-G.2
-
253
-
-
33745742159
-
Mitochondrial fission and apoptosis: an ongoing trial
-
Parone PA, Martinou J-C (2006) Mitochondrial fission and apoptosis: an ongoing trial. Biochim Biophys Acta 1763: 522-530.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 522-530
-
-
Parone, P.A.1
Martinou, J.-C.2
-
254
-
-
3442888512
-
Redox regulation of glial inflammatory response to lipopolysaccharide and interferon γ
-
Pawate S, Shen Q, Fan F, Bhat NR (2004) Redox regulation of glial inflammatory response to lipopolysaccharide and interferon γ. J Neurosci Res 77: 540-551.
-
(2004)
J Neurosci Res
, vol.77
, pp. 540-551
-
-
Pawate, S.1
Shen, Q.2
Fan, F.3
Bhat, N.R.4
-
255
-
-
75749098116
-
The micro-architecture of mitochondria at active zones: electron tomography reveals novel anchoring scaffolds and cristae structures for high-rate metabolism
-
Perkins GA, Thong J, Brown JM, Poquiz PH, Scott RT et al (2010) The micro-architecture of mitochondria at active zones: electron tomography reveals novel anchoring scaffolds and cristae structures for high-rate metabolism. J Neurosci 30(3): 1015-1026.
-
(2010)
J Neurosci
, vol.30
, Issue.3
, pp. 1015-1026
-
-
Perkins, G.A.1
Thong, J.2
Brown, J.M.3
Poquiz, P.H.4
Scott, R.T.5
-
256
-
-
52049089147
-
Mitochondria dysfunction in rat brain with aging: involvement of complex I, reactive oxygen species and cardiolipin
-
Petrosillo G, Matera M, Casanova G, Ruggiero FM, Paradies G (2008) Mitochondria dysfunction in rat brain with aging: involvement of complex I, reactive oxygen species and cardiolipin. Neurochem Int 53(5): 126-131.
-
(2008)
Neurochem Int
, vol.53
, Issue.5
, pp. 126-131
-
-
Petrosillo, G.1
Matera, M.2
Casanova, G.3
Ruggiero, F.M.4
Paradies, G.5
-
257
-
-
0024547664
-
Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity
-
Phillips JP, Campbell SD, Michaud D, Charbonneau M, Hilliker AJ (1989) Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity. Proc Nat Acad Sci USA 86(8): 2761-2765.
-
(1989)
Proc Nat Acad Sci USA
, vol.86
, Issue.8
, pp. 2761-2765
-
-
Phillips, J.P.1
Campbell, S.D.2
Michaud, D.3
Charbonneau, M.4
Hilliker, A.J.5
-
258
-
-
0024547664
-
Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity
-
Phillips JP, Campbell SD, Michaud D, Charbonneau M, Hilliker AJ (1998) Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity. Proc Nat Acad Sci USA 86(8): 2761-2765.
-
(1998)
Proc Nat Acad Sci USA
, vol.86
, Issue.8
, pp. 2761-2765
-
-
Phillips, J.P.1
Campbell, S.D.2
Michaud, D.3
Charbonneau, M.4
Hilliker, A.J.5
-
259
-
-
0037418168
-
Exercise and heart failure: a statement from the American Heart Association Committee on exercise, rehabilitation, and prevention
-
Pina IL, Apstein CS, Balady GJ, Belardinelli R, Chaitman BR, Duscha BD, Fletcher BJ, Fleg JL, Myers JN, Sullivan MJ (2003) Exercise and heart failure: a statement from the American Heart Association Committee on exercise, rehabilitation, and prevention. Circulation 107: 1210-1225.
-
(2003)
Circulation
, vol.107
, pp. 1210-1225
-
-
Pina, I.L.1
Apstein, C.S.2
Balady, G.J.3
Belardinelli, R.4
Chaitman, B.R.5
Duscha, B.D.6
Fletcher, B.J.7
Fleg, J.L.8
Myers, J.N.9
Sullivan, M.J.10
-
260
-
-
46649095406
-
Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopy
-
Plecita-Hlavata L, Lessard M, Šantorova J, Bewersdorf J, Ježek P (2008) Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopy. Biochim Biophys Acta 1777: 834-846.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 834-846
-
-
Plecita-Hlavata, L.1
Lessard, M.2
Šantorova, J.3
Bewersdorf, J.4
Ježek, P.5
-
261
-
-
84864929483
-
Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response
-
Pohjoismäki JLO, Boettger T, Liu Z, Goffart S, Szibor M, Braun T (2012) Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response. Nucl Acids Res 40(14): 6595-6607.
-
(2012)
Nucl Acids Res
, vol.40
, Issue.14
, pp. 6595-6607
-
-
Pohjoismäki, J.L.O.1
Boettger, T.2
Liu, Z.3
Goffart, S.4
Szibor, M.5
Braun, T.6
-
262
-
-
84857718301
-
Preliminary evidences on mitochondrial injury and impaired oxidative metabolism in breast cancer
-
Putignani L, Raffa L, Pescosolido R, Rizza T, Del Chierico F et al (2011) Preliminary evidences on mitochondrial injury and impaired oxidative metabolism in breast cancer. Mitochondrion 12: 363-369.
-
(2011)
Mitochondrion
, vol.12
, pp. 363-369
-
-
Putignani, L.1
Raffa, L.2
Pescosolido, R.3
Rizza, T.4
Del Chierico, F.5
-
263
-
-
27444443028
-
Interactive role of the Toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation
-
Qin L, Li G, Qian X, Liu Y, Wu X, Liu B, Hong JS, Block ML (2005) Interactive role of the Toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation. Glia 52: 78-84.
-
(2005)
Glia
, vol.52
, pp. 78-84
-
-
Qin, L.1
Li, G.2
Qian, X.3
Liu, Y.4
Wu, X.5
Liu, B.6
Hong, J.S.7
Block, M.L.8
-
264
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D (2010) Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab 12(6): 662-667.
-
(2010)
Cell Metab
, vol.12
, Issue.6
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
265
-
-
37749029855
-
Hormesis in aging
-
Rattan SI (2008) Hormesis in aging. Ageing Res Rev 7: 63-78.
-
(2008)
Ageing Res Rev
, vol.7
, pp. 63-78
-
-
Rattan, S.I.1
-
266
-
-
84860914473
-
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
-
Rehmann J, Zhang HJ, Toth PT, Zhang Y, Marsboom G (2012) Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer. FASEB J 26: 2175-2186.
-
(2012)
FASEB J
, vol.26
, pp. 2175-2186
-
-
Rehmann, J.1
Zhang, H.J.2
Toth, P.T.3
Zhang, Y.4
Marsboom, G.5
-
267
-
-
0028055287
-
Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster
-
Reveillaud J, Phillips J, Duyf B, Hilliker A, Kongpachith A, Fleming JE (1994) Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster. Mol cellBiol 14(2): 1302-1307.
-
(1994)
Mol CellBiol
, vol.14
, Issue.2
, pp. 1302-1307
-
-
Reveillaud, J.1
Phillips, J.2
Duyf, B.3
Hilliker, A.4
Kongpachith, A.5
Fleming, J.E.6
-
268
-
-
35448962513
-
A continuous correlation between oxidative stress and telomere shortening in fibroblasts
-
Richter T, von Zglinicki T (2007) A continuous correlation between oxidative stress and telomere shortening in fibroblasts. Exp Gerontol 42: 1039-1042.
-
(2007)
Exp Gerontol
, vol.42
, pp. 1039-1042
-
-
Richter, T.1
von Zglinicki, T.2
-
269
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1a and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P (2005) Nutrient control of glucose homeostasis through a complex of PGC-1a and SIRT1. Nature 434: 113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
270
-
-
33646766829
-
Caloric restriction and mitochondrial function in the ageing myocardium
-
Rohrbach S, Niemann B, Abushouk AM, Holtz J (2006) Caloric restriction and mitochondrial function in the ageing myocardium. Exp Gerontol 41: 525-531.
-
(2006)
Exp Gerontol
, vol.41
, pp. 525-531
-
-
Rohrbach, S.1
Niemann, B.2
Abushouk, A.M.3
Holtz, J.4
-
271
-
-
77952586060
-
Mitochondrial fission and remodeling contributes to muscle atrophy
-
Romanello V, Guadagnin E, Gomes L, Roder I, Sandri C et al (2010) Mitochondrial fission and remodeling contributes to muscle atrophy. EMBO J 29: 1774-185.
-
(2010)
EMBO J
, vol.29
, pp. 1185-1774
-
-
Romanello, V.1
Guadagnin, E.2
Gomes, L.3
Roder, I.4
Sandri, C.5
-
272
-
-
79955783575
-
Voluntary exercise in pregnant rats positively influences fetal growth without initiating a maternal physiological stress response
-
Rosa BV, Firth EX, Blair HT, Vickers MH, Morel PCH (2011) Voluntary exercise in pregnant rats positively influences fetal growth without initiating a maternal physiological stress response. Am J Physiol - Reg Physiol 300(5): R1134-R1141.
-
(2011)
Am J Physiol - Reg Physiol
, vol.300
, Issue.5
-
-
Rosa, B.V.1
Firth, E.X.2
Blair, H.T.3
Vickers, M.H.4
Morel, P.C.H.5
-
273
-
-
38849201088
-
Mitochondrial connexin43 as a new layer in the pathophysiology of myocardial ischaemia-reperfusion injury
-
Ruiz-Meana M, Rodri{dotless}́guez-Sinovas A, Cabestrero A, Boengler K, Heusch G, Garcia-Dorado D (2008) Mitochondrial connexin43 as a new layer in the pathophysiology of myocardial ischaemia-reperfusion injury. Cardiovasc Res 77: 325-333.
-
(2008)
Cardiovasc Res
, vol.77
, pp. 325-333
-
-
Ruiz-Meana, M.1
Rodríguez-Sinovas, A.2
Cabestrero, A.3
Boengler, K.4
Heusch, G.5
Garcia-Dorado, D.6
-
274
-
-
79953232671
-
Exercise increases mitochondrial pgc-1α content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis
-
Safdar A, Little JP, Stokl AJ, Hettinga BP, Akhtar M, Tarnopolsky MA (2011) Exercise increases mitochondrial pgc-1α content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis. J Biol Chem 286: 10605-10617.
-
(2011)
J Biol Chem
, vol.286
, pp. 10605-10617
-
-
Safdar, A.1
Little, J.P.2
Stokl, A.J.3
Hettinga, B.P.4
Akhtar, M.5
Tarnopolsky, M.A.6
-
275
-
-
84868302530
-
Sedentary behavior and physical activity are independently related to functional fitness in older adults
-
Santos DA, Silva AM, Baptista F, Santos R, Vale S, Mota J, Sardinha LB (2002) Sedentary behavior and physical activity are independently related to functional fitness in older adults. Exptl Gerontol 37: 908-912.
-
(2002)
Exptl Gerontol
, vol.37
, pp. 908-912
-
-
Santos, D.A.1
Silva, A.M.2
Baptista, F.3
Santos, R.4
Vale, S.5
Mota, J.6
Sardinha, L.B.7
-
276
-
-
54349125852
-
Podospora anserina: a model organism to study mechanisms of healthy ageing
-
Scheckhuber CQ, Osiewacz HD (2008) Podospora anserina: a model organism to study mechanisms of healthy ageing. Mol Genet Genomics 280: 365-374.
-
(2008)
Mol Genet Genomics
, vol.280
, pp. 365-374
-
-
Scheckhuber, C.Q.1
Osiewacz, H.D.2
-
277
-
-
0037013154
-
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
-
Schmitt CA, Fridman JS, Yang M, Lee S, Baranov E, Hoffman RM, Lowe SW (2002) A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy. Cell 109: 335-346.
-
(2002)
Cell
, vol.109
, pp. 335-346
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Lee, S.4
Baranov, E.5
Hoffman, R.M.6
Lowe, S.W.7
-
278
-
-
34748850786
-
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
-
Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M (2007) Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metabolism 6(4): 280-293.
-
(2007)
Cell Metabolism
, vol.6
, Issue.4
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
279
-
-
26444463430
-
Proteins that fuse and fragment mitochondria in apoptosis: con-fissing a deadly con-fusion
-
Scorrano L (2005) Proteins that fuse and fragment mitochondria in apoptosis: con-fissing a deadly con-fusion. J Bioenerg Biomemb 37(3): 165-170.
-
(2005)
J Bioenerg Biomemb
, vol.37
, Issue.3
, pp. 165-170
-
-
Scorrano, L.1
-
280
-
-
57649219323
-
The role of external and matrix pH in mitochondrial reactive oxygen species generation
-
Selivanov VA, Zeak JA, Roca J, Cascante M, Trucco M, Votyakova TV (2008) The role of external and matrix pH in mitochondrial reactive oxygen species generation. J Biol Chem 283(43): 29292-29300.
-
(2008)
J Biol Chem
, vol.283
, Issue.43
, pp. 29292-29300
-
-
Selivanov, V.A.1
Zeak, J.A.2
Roca, J.3
Cascante, M.4
Trucco, M.5
Votyakova, T.V.6
-
281
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, Tsujimoto Y (2004) Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 6: 1221-1228.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
282
-
-
37349051709
-
Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase
-
Shinmura K, Tamaki K, Saito K, Nakano Y, Tobe T, Bolli R (2007) Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase. Circulation 116: 2809-2817.
-
(2007)
Circulation
, vol.116
, pp. 2809-2817
-
-
Shinmura, K.1
Tamaki, K.2
Saito, K.3
Nakano, Y.4
Tobe, T.5
Bolli, R.6
-
283
-
-
57349200508
-
Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1
-
Shinmura K, Tamaki K, Bolli R (2008) Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1. Am J Physiol Heart Circ Physiol 295: H2348-H2355.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Shinmura, K.1
Tamaki, K.2
Bolli, R.3
-
284
-
-
79952585486
-
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
-
Shirendeb U, Reddy AP, Manczak M, Calkins MJ, Mao P et al (2011) Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage. Hum Mol Gen 20(7): 1438-1455.
-
(2011)
Hum Mol Gen
, vol.20
, Issue.7
, pp. 1438-1455
-
-
Shirendeb, U.1
Reddy, A.P.2
Manczak, M.3
Calkins, M.J.4
Mao, P.5
-
285
-
-
38949099761
-
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
-
Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD (2008) Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 4: 176-184.
-
(2008)
Autophagy
, vol.4
, pp. 176-184
-
-
Simonsen, A.1
Cumming, R.C.2
Brech, A.3
Isakson, P.4
Schubert, D.R.5
Finley, K.D.6
-
286
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273(5271): 59-63.
-
(1996)
Science
, vol.273
, Issue.5271
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
287
-
-
56349133547
-
Positioning mitochondrial plasticity within cellular signaling cascades
-
Soubannier V, McBride HM (2009) Positioning mitochondrial plasticity within cellular signaling cascades. Biochim Biophys Acta 1793: 154-170.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 154-170
-
-
Soubannier, V.1
McBride, H.M.2
-
288
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and app vesicles in neurons and enhances oxidative stress
-
Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow E-M (2002) Tau blocks traffic of organelles, neurofilaments, and app vesicles in neurons and enhances oxidative stress. J Cell Biol 156: 1051-1063.
-
(2002)
J Cell Biol
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.-M.5
-
289
-
-
79952749507
-
Listeria monocytogenes transiently alters mitochondrial dynamics during infection
-
Stavru F, Bouillaud F, Sartori A, Ricquier D, Cossart P (2011) Listeria monocytogenes transiently alters mitochondrial dynamics during infection. Proc Nat Acad Sci USA 108(9): 3612-3617.
-
(2011)
Proc Nat Acad Sci USA
, vol.108
, Issue.9
, pp. 3612-3617
-
-
Stavru, F.1
Bouillaud, F.2
Sartori, A.3
Ricquier, D.4
Cossart, P.5
-
290
-
-
80054691291
-
Exercise training increases mitochondrial biogenesis in the brain
-
Steiner JL, Murphy EA, McClellan JL, Carmichael MD, Davis JM (2011) Exercise training increases mitochondrial biogenesis in the brain. J Appl Physiol 111(4): 1066-1071.
-
(2011)
J Appl Physiol
, vol.111
, Issue.4
, pp. 1066-1071
-
-
Steiner, J.L.1
Murphy, E.A.2
McClellan, J.L.3
Carmichael, M.D.4
Davis, J.M.5
-
291
-
-
74149088456
-
Aging of different avian cultured cells: lack of ROS-induced damage and quality control mechanisms
-
Strecker V, Mai S, Muster B, Beneke S, Bürkle A, Bereiter-Hahn J, Jendrach M (2010) Aging of different avian cultured cells: lack of ROS-induced damage and quality control mechanisms. Mech Ageing Develop 131: 48-59.
-
(2010)
Mech Ageing Develop
, vol.131
, pp. 48-59
-
-
Strecker, V.1
Mai, S.2
Muster, B.3
Beneke, S.4
Bürkle, A.5
Bereiter-Hahn, J.6
Jendrach, M.7
-
292
-
-
84861889858
-
Impact of chronic exercise training on the blood pressure response to orthostatic stimulation
-
Sugawara J, Komine H, Miyazawa T, Imai T, Fisher JP, Ogoh S (2012) Impact of chronic exercise training on the blood pressure response to orthostatic stimulation. J Appl Physiol 112: 1891-1896.
-
(2012)
J Appl Physiol
, vol.112
, pp. 1891-1896
-
-
Sugawara, J.1
Komine, H.2
Miyazawa, T.3
Imai, T.4
Fisher, J.P.5
Ogoh, S.6
-
293
-
-
77449115593
-
Endurance exercise causes mitochondrial and oxidative stress in rat liver: effects of a combination of mitochondrial targeting nutrients
-
Sun L, Shen W, Liu Z, Guan S, Liu J, Ding S (2010) Endurance exercise causes mitochondrial and oxidative stress in rat liver: effects of a combination of mitochondrial targeting nutrients. Life Sci 86(1-2): 39-44.
-
(2010)
Life Sci
, vol.86
, Issue.1-2
, pp. 39-44
-
-
Sun, L.1
Shen, W.2
Liu, Z.3
Guan, S.4
Liu, J.5
Ding, S.6
-
294
-
-
84865013141
-
Microglial cathepsin b contributes to the initiation of peripheral inflammation-induced chronic pain
-
Sun L, Wu Z, Hayashi Y, Peters C, Tsuda M, Inoue K, Nakanishi H (2012) Microglial cathepsin b contributes to the initiation of peripheral inflammation-induced chronic pain. J Neurosci 32(33): 11330-113.
-
(2012)
J Neurosci
, vol.32
, Issue.33
, pp. 11113-11330
-
-
Sun, L.1
Wu, Z.2
Hayashi, Y.3
Peters, C.4
Tsuda, M.5
Inoue, K.6
Nakanishi, H.7
-
295
-
-
0019319464
-
Regulation of cellular energy metabolism: the Crabtree effect
-
Sussman I, Erecinska M, Wilson DF (1980) Regulation of cellular energy metabolism: the Crabtree effect. Biochim Biophys Acta 591: 209-223.
-
(1980)
Biochim Biophys Acta
, vol.591
, pp. 209-223
-
-
Sussman, I.1
Erecinska, M.2
Wilson, D.F.3
-
296
-
-
80053892506
-
Brain aging, Alzheimer's disease, and mitochondria
-
Swerdlow RH (2011) Brain aging, Alzheimer's disease, and mitochondria. Biochim Biophys Acta 1812: 1630-1639.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1630-1639
-
-
Swerdlow, R.H.1
-
297
-
-
4944222095
-
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2{thorn} waves and protects against Ca2{thorn}-mediated apoptosis
-
Szabadkai G, Simoni AM, Chami M, Wieckowski MR, Youle RJ, Rizzuto R (2004) Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2{thorn} waves and protects against Ca2{thorn}-mediated apoptosis. Mol Cell 16: 59-68.
-
(2004)
Mol Cell
, vol.16
, pp. 59-68
-
-
Szabadkai, G.1
Simoni, A.M.2
Chami, M.3
Wieckowski, M.R.4
Youle, R.J.5
Rizzuto, R.6
-
298
-
-
34547097247
-
Brain IRS2 signaling coordinates life span and nutrient homeostasis
-
Taguchi A, Wartschow LM, White MF (2007) Brain IRS2 signaling coordinates life span and nutrient homeostasis. Science 317: 369-372.
-
(2007)
Science
, vol.317
, pp. 369-372
-
-
Taguchi, A.1
Wartschow, L.M.2
White, M.F.3
-
299
-
-
33845999916
-
Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging
-
Tahara EB, Barros MH, Oliveira GA, Netto LE, Kowaltowski AJ (2007) Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging. FASEB J 21: 274-283.
-
(2007)
FASEB J
, vol.21
, pp. 274-283
-
-
Tahara, E.B.1
Barros, M.H.2
Oliveira, G.A.3
Netto, L.E.4
Kowaltowski, A.J.5
-
300
-
-
38549101188
-
Quality control of mitochondria: protection against neurodegeneration and ageing
-
Tatsuta T, Langer T (2008) Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J 27: 306-314.
-
(2008)
EMBO J
, vol.27
, pp. 306-314
-
-
Tatsuta, T.1
Langer, T.2
-
301
-
-
27644467802
-
Autophagy in cardiac myocyte homeostasis, aging, and pathology
-
Terman A, Brunk UT (2005) Autophagy in cardiac myocyte homeostasis, aging, and pathology. Cardiovasc Res 68: 355-365.
-
(2005)
Cardiovasc Res
, vol.68
, pp. 355-365
-
-
Terman, A.1
Brunk, U.T.2
-
302
-
-
75349112375
-
Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging
-
Terman A, Kurz T, Navratil M, Ariaga EA, Brunk UT (2010) Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging. Antioxidants & Redox Signalling 12(4): 503-535.
-
(2010)
Antioxidants & Redox Signalling
, vol.12
, Issue.4
, pp. 503-535
-
-
Terman, A.1
Kurz, T.2
Navratil, M.3
Ariaga, E.A.4
Brunk, U.T.5
-
303
-
-
84872577068
-
RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice
-
Thomas RR, Khan SM, Smigrodzki RM, Onyango IG, Dennis J et al (2012) RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice. Aging 4(9): 620-635.
-
(2012)
Aging
, vol.4
, Issue.9
, pp. 620-635
-
-
Thomas, R.R.1
Khan, S.M.2
Smigrodzki, R.M.3
Onyango, I.G.4
Dennis, J.5
-
304
-
-
0345596416
-
Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging
-
Tian L, Cai Q, Wei H (1998) Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging. Free Radic Biol Med 24(9): 1477-1484.
-
(1998)
Free Radic Biol Med
, vol.24
, Issue.9
, pp. 1477-1484
-
-
Tian, L.1
Cai, Q.2
Wei, H.3
-
305
-
-
34248546383
-
Mitoptosis: different pathways for mitochondrial execution
-
Tinari A, Garofalo T, Sorice M, Esposti MD, Malorni W (2007) Mitoptosis: different pathways for mitochondrial execution. Autophagy 3: 282-284.
-
(2007)
Autophagy
, vol.3
, pp. 282-284
-
-
Tinari, A.1
Garofalo, T.2
Sorice, M.3
Esposti, M.D.4
Malorni, W.5
-
306
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410: 227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
307
-
-
0036007110
-
Model organisms as a guide to mammalian aging
-
Tissenbaum HA, Guarente L (2002) Model organisms as a guide to mammalian aging. Dev Cell 2: 9-19.
-
(2002)
Dev Cell
, vol.2
, pp. 9-19
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
308
-
-
33646676497
-
Mitochondrial redox control of matrix metalloproteinase signaling in resistance arteries
-
Touyz RM (2006) Mitochondrial redox control of matrix metalloproteinase signaling in resistance arteries. Arterioscler Thromb Vasc Bio 26: 685-688.
-
(2006)
Arterioscler Thromb Vasc Bio
, vol.26
, pp. 685-688
-
-
Touyz, R.M.1
-
309
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A, Wredenberg A, Falkenberg M et al (2004) Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429: 417-423.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
-
310
-
-
29144458899
-
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
-
Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, Khvorostov I, Spelbrink JN, Wibom R, Jacobs HT, Larsson NG (2005) Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proc Natl Acad Sci USA 102: 17993-17998.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17993-17998
-
-
Trifunovic, A.1
Hansson, A.2
Wredenberg, A.3
Rovio, A.T.4
Dufour, E.5
Khvorostov, I.6
Spelbrink, J.N.7
Wibom, R.8
Jacobs, H.T.9
Larsson, N.G.10
-
311
-
-
71849116489
-
The mitochondrial brain: from mitochondrial genome to neurodegeneration
-
Turnbull HE, Lax NZ, Diodato D, Ansorge O, Turnbull DM (2010) The mitochondrial brain: from mitochondrial genome to neurodegeneration. Biochim Biophys Acta 1802(1): 111-121.
-
(2010)
Biochim Biophys Acta
, vol.1802
, Issue.1
, pp. 111-121
-
-
Turnbull, H.E.1
Lax, N.Z.2
Diodato, D.3
Ansorge, O.4
Turnbull, D.M.5
-
312
-
-
49349102894
-
Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view
-
Twig G, Hyde B, Shirihai OS (2008) Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim Biophys Acta 1777: 1092-1097.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 1092-1097
-
-
Twig, G.1
Hyde, B.2
Shirihai, O.S.3
-
313
-
-
34447307110
-
Identification of cultivation-independent markers of human endothelial cell senescence in vitro
-
Unterluggauer H, Hütter E, Voglauer R, Grillari J, Vöth M, Bereiter-Hahn J, Jansen-Dürr P, Jendrach M (2007) Identification of cultivation-independent markers of human endothelial cell senescence in vitro. Biogerontol 8: 383-397.
-
(2007)
Biogerontol
, vol.8
, pp. 383-397
-
-
Unterluggauer, H.1
Hütter, E.2
Voglauer, R.3
Grillari, J.4
Vöth, M.5
Bereiter-Hahn, J.6
Jansen-Dürr, P.7
Jendrach, M.8
-
314
-
-
12144288373
-
Lifelong reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
van Remmen H, Ikeno Y, Hamilton M et al (2003) Lifelong reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics 16(1): 29-37.
-
(2003)
Physiol Genomics
, vol.16
, Issue.1
, pp. 29-37
-
-
van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
-
315
-
-
74149093894
-
Calorie restriction causes healthy life span extension in filamentous fungus Podospora anserina
-
vanDiepeningen A, Maas MFPM, Huberts DHEW, Goedbloed DJ, Engelmoer DJP, Slakhorst SM, Koopmanschap AB, Krause F, Dencher NA, Sellem CH, Sainsard-Chanet A, Hoekstra RF, Debets AJM (2010) Calorie restriction causes healthy life span extension in filamentous fungus Podospora anserina. Mech Aging Devel 131: 60-68.
-
(2010)
Mech Aging Devel
, vol.131
, pp. 60-68
-
-
vanDiepeningen, A.1
Maas, M.F.P.M.2
Huberts, D.H.E.W.3
Goedbloed, D.J.4
Engelmoer, D.J.P.5
Slakhorst, S.M.6
Koopmanschap, A.B.7
Krause, F.8
Dencher, N.A.9
Sellem, C.H.10
Sainsard-Chanet, A.11
Hoekstra, R.F.12
Debets, A.J.M.13
-
316
-
-
0033429333
-
Mechanisms of life span determination in Caenorhabditis elegans
-
Vanfleteren JR, Braeckman BP (1999) Mechanisms of life span determination in Caenorhabditis elegans. Neurobiol Aging 20: 487-502.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 487-502
-
-
Vanfleteren, J.R.1
Braeckman, B.P.2
-
317
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virág L, Szabó C (2002) The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54: 375-429.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 375-429
-
-
Virág, L.1
Szabó, C.2
-
318
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C, Zhou C, Huang Y, Cui M, deVries RLA, Kim J et al (2010) PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Nat Aca Sci 107(1): 378-383.
-
(2010)
Proc Nat Aca Sci
, vol.107
, Issue.1
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
deVries, R.L.A.5
Kim, J.6
-
319
-
-
20144388541
-
The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes
-
Walder K, Kerr-Bayles L, Civitarese A, Jowett J, Curran J, Elliott K et al (2005) The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes. Diabetol 48: 459-468.
-
(2005)
Diabetol
, vol.48
, pp. 459-468
-
-
Walder, K.1
Kerr-Bayles, L.2
Civitarese, A.3
Jowett, J.4
Curran, J.5
Elliott, K.6
-
320
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
-
Wallace DC (2005) A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 39: 359-407.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
321
-
-
67650732998
-
Impaired balance of mitochondria fission and fusion in Alzheimer disease
-
Wang X, Su B, Lee HG, Perry G, Zhu X (2009) Impaired balance of mitochondria fission and fusion in Alzheimer disease. J Neurosci 29(28): 9090-9103.
-
(2009)
J Neurosci
, vol.29
, Issue.28
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Perry, G.4
Zhu, X.5
-
322
-
-
0004970436
-
-
Berlin: Springer Verlag. Translated: The metabolism of tumors. Lindon: Arnold Constable 1930
-
Warburg O (1930) Über den Stoffwechsel der Tumore. Berlin: Springer Verlag. Translated: The metabolism of tumors. Lindon: Arnold Constable 1930.
-
(1930)
Über den Stoffwechsel der Tumore
-
-
Warburg, O.1
-
324
-
-
34548802393
-
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment
-
Weissman L, Jo DG, Sorensen M, de Souza-Pinto NC, Markesbery WR, Mattson MP, Bohr VA (2007) Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment. Nucleic Acids Res 35(16): 5545-5555.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.16
, pp. 5545-5555
-
-
Weissman, L.1
Jo, D.G.2
Sorensen, M.3
de Souza-Pinto, N.C.4
Markesbery, W.R.5
Mattson, M.P.6
Bohr, V.A.7
-
325
-
-
64349105425
-
Eating to exit: autophagy-enabled senescence revealed
-
White E, Lowe SW (2009) Eating to exit: autophagy-enabled senescence revealed. Genes Dev 23: 784-787.
-
(2009)
Genes Dev
, vol.23
, pp. 784-787
-
-
White, E.1
Lowe, S.W.2
-
326
-
-
33750706163
-
Mitochondrial DNA damage and the aging process-facts and imaginations
-
Wiesner RJ, Zsurka G, Kunz WS (2006) Mitochondrial DNA damage and the aging process-facts and imaginations. Free Radic Res 40: 1284-1294.
-
(2006)
Free Radic Res
, vol.40
, pp. 1284-1294
-
-
Wiesner, R.J.1
Zsurka, G.2
Kunz, W.S.3
-
327
-
-
0016663293
-
The effect of age on mitochondria. Ultrastructure and enzyme cytochemistry
-
Wilson PD, Franks LM (1975) The effect of age on mitochondria. Ultrastructure and enzyme cytochemistry. Biochem Soc Trans 3: 126-128.
-
(1975)
Biochem Soc Trans
, vol.3
, pp. 126-128
-
-
Wilson, P.D.1
Franks, L.M.2
-
328
-
-
0036217327
-
Aerobic exercise reduces cardiomyocyte hypertrophy and increases contractility, Ca2+ sensitivity and SERCA-2 in rat after myocardial infarction
-
Wisloff U, Loennechen JP, Currie S, Smith GL, Ellingsen O (2002) Aerobic exercise reduces cardiomyocyte hypertrophy and increases contractility, Ca2+ sensitivity and SERCA-2 in rat after myocardial infarction. Cardiovasc Res 54: 162-174.
-
(2002)
Cardiovasc Res
, vol.54
, pp. 162-174
-
-
Wisloff, U.1
Loennechen, J.P.2
Currie, S.3
Smith, G.L.4
Ellingsen, O.5
-
330
-
-
34548271691
-
Pathogenic mitochondrial DNA mutations in protein-coding genes
-
Wong LJ (2007) Pathogenic mitochondrial DNA mutations in protein-coding genes. Muscle Nerve 36: 279-293.
-
(2007)
Muscle Nerve
, vol.36
, pp. 279-293
-
-
Wong, L.J.1
-
331
-
-
10244236554
-
Mitochondrial degeneration in amyotrophic lateral sclerosis
-
Xu Z, Jung C, Higgins C, Levine J, Kong J (2004) Mitochondrial degeneration in amyotrophic lateral sclerosis. J Bioenerg Biomembr 36: 395-399.
-
(2004)
J Bioenerg Biomembr
, vol.36
, pp. 395-399
-
-
Xu, Z.1
Jung, C.2
Higgins, C.3
Levine, J.4
Kong, J.5
-
332
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, Cordon-Cardo C, Lowe SW (2007) Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445: 656-660.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
333
-
-
78650455712
-
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans
-
Article ID e1000556
-
Yang W, Hekimi S (2010) A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biology 8(12), Article ID e1000556.
-
(2010)
PLoS Biology
, vol.8
, Issue.12
-
-
Yang, W.1
Hekimi, S.2
-
334
-
-
77954158731
-
High mitochondrial DNA copy number has detrimental effects in mice
-
Ylikallio E, Tyynismaa H, Tsutsui H, Ide T, Suomalainen A (2010) High mitochondrial DNA copy number has detrimental effects in mice. Hum Mol Genet 19(13): 2695-2705.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.13
, pp. 2695-2705
-
-
Ylikallio, E.1
Tyynismaa, H.2
Tsutsui, H.3
Ide, T.4
Suomalainen, A.5
-
335
-
-
33749265862
-
Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1
-
Yoon YS, Yoon DS, Lim IK, Yoon SH, Chung HY, Rojo M, Malka F, Jou MJ, Martinou JC, Yoon G (2006) Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1. J Cell Physiol 209: 68-480.
-
(2006)
J Cell Physiol
, vol.209
, pp. 68-480
-
-
Yoon, Y.S.1
Yoon, D.S.2
Lim, I.K.3
Yoon, S.H.4
Chung, H.Y.5
Rojo, M.6
Malka, F.7
Jou, M.J.8
Martinou, J.C.9
Yoon, G.10
-
336
-
-
0037402505
-
The role of oxidative stress in diabetic vascular and neural disease
-
Yorek M (2003) The role of oxidative stress in diabetic vascular and neural disease. Free Rad Res 37(5): 471-480.
-
(2003)
Free Rad Res
, vol.37
, Issue.5
, pp. 471-480
-
-
Yorek, M.1
-
337
-
-
33644552417
-
Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
-
Yu T, Robotham JL, Yoon Y (2006) Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc Natl Acad Sci U S A 103: 2653-2681.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2653-2681
-
-
Yu, T.1
Robotham, J.L.2
Yoon, Y.3
-
338
-
-
46749156297
-
Mitochondrial fission mediates high glucose induced cell death through elevated production of reactive oxygen species
-
Yu T, Sheu SS, Robotham JL, Yoon Y (2008) Mitochondrial fission mediates high glucose induced cell death through elevated production of reactive oxygen species. Cardiovasc Res 79: 341-351.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 341-351
-
-
Yu, T.1
Sheu, S.S.2
Robotham, J.L.3
Yoon, Y.4
-
339
-
-
84870060477
-
Relationship between physical activity and brain atrophy progression
-
Yuki A, Lee S, Kim H, Kozakai R, Ando F, Shimokata H (2012) Relationship between physical activity and brain atrophy progression. Med Sci Sports Exerc 44(12): 2362-2368.
-
(2012)
Med Sci Sports Exerc
, vol.44
, Issue.12
, pp. 2362-2368
-
-
Yuki, A.1
Lee, S.2
Kim, H.3
Kozakai, R.4
Ando, F.5
Shimokata, H.6
-
340
-
-
16544365687
-
p66ShcA modulates tissue response to hindlimb ischemia
-
Zaccagnini G, Martelli F, Fasanaro P, Magenta A, Gaetano C, Di Carlo A, Biglioli P, Giorgio M, Martin-Padura I, Pelicci PG, Capogrossi MC (2004) p66ShcA modulates tissue response to hindlimb ischemia. Circulation 109: 2917-2923.
-
(2004)
Circulation
, vol.109
, pp. 2917-2923
-
-
Zaccagnini, G.1
Martelli, F.2
Fasanaro, P.3
Magenta, A.4
Gaetano, C.5
Di Carlo, A.6
Biglioli, P.7
Giorgio, M.8
Martin-Padura, I.9
Pelicci, P.G.10
Capogrossi, M.C.11
-
341
-
-
38849190029
-
OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion
-
Zanna C, Ghelli A, Procelli AM, Karbowski M, Youle RJ et al (2008) OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. Brain 13(2): 352-367.
-
(2008)
Brain
, vol.13
, Issue.2
, pp. 352-367
-
-
Zanna, C.1
Ghelli, A.2
Procelli, A.M.3
Karbowski, M.4
Youle, R.J.5
-
342
-
-
24144450324
-
Mitochondrial inhibition and oxidative stress: reciprocating players in neurodegeneration
-
Zeevalk GD, Bernard LP, Song C, Gluck M, Ehrhart J (2005) Mitochondrial inhibition and oxidative stress: reciprocating players in neurodegeneration. Antioxid Redox Signal 7: 1117-1139.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1117-1139
-
-
Zeevalk, G.D.1
Bernard, L.P.2
Song, C.3
Gluck, M.4
Ehrhart, J.5
-
343
-
-
33645524328
-
Glycated proteins stimulate reactive oxygen species production in cardiac myocytes
-
Zhang M, Kho AL, Anikumar N, Chibber R, Pagno PJ, Shah AM, Cave AC (2006) Glycated proteins stimulate reactive oxygen species production in cardiac myocytes. Circulation 113: 1235-1243.
-
(2006)
Circulation
, vol.113
, pp. 1235-1243
-
-
Zhang, M.1
Kho, A.L.2
Anikumar, N.3
Chibber, R.4
Pagno, P.J.5
Shah, A.M.6
Cave, A.C.7
-
344
-
-
69449090286
-
The novel conserved mitochondrial inner-membrane protein MTGM regulates mitochondrial morphology and cell proliferation
-
Zhao J, Liu T, Jin S-B, Tomllin N, Castro J, Shupliakov O, Nistér M (2009) The novel conserved mitochondrial inner-membrane protein MTGM regulates mitochondrial morphology and cell proliferation. J Cell Sci 122: 2252-2262.
-
(2009)
J Cell Sci
, vol.122
, pp. 2252-2262
-
-
Zhao, J.1
Liu, T.2
Jin, S.-B.3
Tomllin, N.4
Castro, J.5
Shupliakov, O.6
Nistér, M.7
-
345
-
-
77953230237
-
Increasing mitochondrial superoxide dismutase abundance leads to impairments in protein quality control and ROS scavenging systems and to lifespan shortening
-
Zintel S, Schwitalla D, Luce K, Hamann A, Osiewacz HD (2010) Increasing mitochondrial superoxide dismutase abundance leads to impairments in protein quality control and ROS scavenging systems and to lifespan shortening. Exp Gerontol 45: 525-532.
-
(2010)
Exp Gerontol
, vol.45
, pp. 525-532
-
-
Zintel, S.1
Schwitalla, D.2
Luce, K.3
Hamann, A.4
Osiewacz, H.D.5
-
346
-
-
68949116271
-
Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes
-
Zorzano A, Liesaa M, Palacína M (2009) Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes. Int J Biochem Cell Biol 41: 1846-1854.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1846-1854
-
-
Zorzano, A.1
Liesaa, M.2
Palacína, M.3
-
347
-
-
2442589922
-
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
-
Zuchner S, Mersiyanova IV, Muglia M, Bissar-Tadmour N, Rochelle J et al (2004) Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat Genet 36: 449-451.
-
(2004)
Nat Genet
, vol.36
, pp. 449-451
-
-
Zuchner, S.1
Mersiyanova, I.V.2
Muglia, M.3
Bissar-Tadmour, N.4
Rochelle, J.5
-
348
-
-
34248225298
-
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function
-
Zunino R, Schauss A, Rippstein P, Andrade-Navarro M, McBride HM (2007) The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. J Cell Sci 120: 1178-1188.
-
(2007)
J Cell Sci
, vol.120
, pp. 1178-1188
-
-
Zunino, R.1
Schauss, A.2
Rippstein, P.3
Andrade-Navarro, M.4
McBride, H.M.5
|