A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 2, 2012, Pages 621-626

  Fusco, Salvatore ^a   Ripoli, Cristian ^a   Podda, Maria Vittoria ^a   Ranieri, Sofia Chiatamone ^a,f   Leone, Lucia ^a   Toietta, Gabriele ^b   McBurney, Michael W ^c   Schütz, Günther ^d   Riccio, Antonella ^e   Grassi, Claudio ^a   Galeotti, Tommaso ^a   Pani, Giovambattista ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^c OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f S MARIA NUOVA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NEURONAL NITRIC OXIDE SYNTHASE; NEUROTROPHIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN NERVE CELL; CALORIC RESTRICTION; CELL METABOLISM; CELL SURVIVAL; CHROMATIN; CONTROLLED STUDY; ENERGY METABOLISM; FOREBRAIN; GENE EXPRESSION; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MEMORY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; NUTRIENT AVAILABILITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SOCIAL BEHAVIOR; TRANSCRIPTION REGULATION;

ANALYSIS OF VARIANCE; ANIMALS; CALORIC RESTRICTION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION; LONG-TERM POTENTIATION; MALE; MEMORY; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NEURONAL PLASTICITY; NEURONS; PROSENCEPHALON; PSYCHOMOTOR PERFORMANCE; SIRTUIN 1; SOCIAL BEHAVIOR;

ANIMALIA; MUS;

EID: 84855994224     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109237109     Document Type: Article

References (43)

1. Fontana L, Partridge L, Longo VD (2010) Extending healthy life span-From yeast to humans. Science 328:321-326.
2. Maalouf M, Rho JM, Mattson MP (2009) The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Brain Res Rev 59: 293-315.
3. Takeda S, et al. (2010) Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes. Proc Natl Acad Sci USA 107:7036-7041.
4. de la Monte SM (2009) Insulin resistance and Alzheimer's disease. BMB Rep 42: 475-481.
5. Haigis MC, Guarente LP (2006) Mammalian sirtuins-Emerging roles in physiology, aging, and calorie restriction. Genes Dev 20:2913-2921. (Pubitemid 44771725)
6. Finkel T, Deng CX, Mostoslavsky R (2009) Recent progress in the biology and physiology of sirtuins. Nature 460:587-591.
7. Cohen DE, Supinski AM, Bonkowski MS, Donmez G, Guarente LP (2009) Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction. Genes Dev 23:2812-2817.
8. Qin W, et al. (2006) Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem 281:21745-21754. (Pubitemid 44181878)
9. Donmez G, Wang D, Cohen DE, Guarente L (2010) SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell 142:320-332.
10. Riccio A, Ahn S, Davenport CM, Blendy JA, Ginty DD (1999) Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 286:2358-2361. (Pubitemid 30016901)
11. Finkbeiner S (2000) CREB couples neurotrophin signals to survival messages. Neuron 25:11-14.
12. Zuccato C, et al. (2001) Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293:493-498. (Pubitemid 32679077)
13. Cui L, et al. (2006) Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 127:59-69. (Pubitemid 44466642)
14. Caccamo A, Maldonado MA, Bokov AF, Majumder S, Oddo S (2010) CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 107:22687-22692.
15. Altarejos JY, Montminy M (2011) CREB and the CRTC co-activators: Sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol 12:141-151.
16. Gao J, et al. (2010) A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 466:1105-1109.
17. Halagappa VK, et al. (2007) Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol Dis 26:212-220. (Pubitemid 46436499)
18. Mantamadiotis T, et al. (2002) Disruption of CREB function in brain leads to neurodegeneration. Nat Genet 31:47-54.
19. Bevins RA, Besheer J (2006) Object recognition in rats andmice: A one-trial non-matchingto- sample learning task to study 'recognition memory'. Nat Protoc 1:1306-1311.
20. Bourtchuladze R, et al. (1994) Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell 79:59-68.
21. Koizumi H, Hashimoto K, Iyo M (2006) Dietary restriction changes behaviours in brainderived neurotrophic factor heterozygous mice: Role of serotonergic system. Eur J Neurosci 24:2335-2344. (Pubitemid 44622354)
22. Nelson RJ, et al. (1995) Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature 378:383-386.
23. Zhang X, et al. (2005) Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci USA 102:4459-4464. (Pubitemid 40397134)
24. Hori N, Hirotsu I, Davis PJ, Carpenter DO (1992) Long-term potentiation is lost in aged rats but preserved by calorie restriction. Neuroreport 3:1085-1088. (Pubitemid 23034707)
25. Balschun D, et al. (2003) Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory? J Neurosci 23:6304-6314. (Pubitemid 36875632)
26. Nisoli E, Clementi E, Moncada S, Carruba MO (2004) Mitochondrial biogenesis as a cellular signaling framework. Biochem Pharmacol 67:1-15. (Pubitemid 37518530)
27. Rodgers JT, et al. (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434:113-118. (Pubitemid 40349395)
28. Vaquero A, et al. (2004) Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell 16:93-105. (Pubitemid 39330155)
29. Riccio A, et al. (2006) A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons. Mol Cell 21:283-294. (Pubitemid 43099943)
30. Impey S, et al. (2004) Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell 119:1041-1054. (Pubitemid 40037616)
31. Nemoto S, Fergusson MM, Finkel T (2004) Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 306:2105-2108. (Pubitemid 40007664)
32. Vaziri H, et al. (2001) hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107:149-159. (Pubitemid 33035942)
33. Brunet A, et al. (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303:2011-2015. (Pubitemid 38393275)
34. Sauve AA, Schramm VL (2003) Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry. Biochemistry 42:9249-9256. (Pubitemid 36959231)
35. Du K, Asahara H, Jhala US, Wagner BL, Montminy M (2000) Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo. Mol Cell Biol 20:4320-4327. (Pubitemid 30346626)
36. Peunova N, Enikolopov G (1995) Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells. Nature 375:68-73.
37. Boily G, et al. (2008) SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One 3:e1759.
38. Altarejos JY, et al. (2008) The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med 14:1112-1117.
39. Cohen HY, et al. (2004) Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305:390-392. (Pubitemid 38938153)
40. Nisoli E, et al. (2005) Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310:314-317. (Pubitemid 41457197)
41. Bedogni B, et al. (2003) Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival. J Biol Chem 278:16510-16519. (Pubitemid 36799511)
42. Dawson VL, Dawson TM (1998) Nitric oxide in neurodegeneration. Prog Brain Res 118: 215-229. (Pubitemid 28530669)
43. St-Pierre J, et al. (2006) Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397-408. (Pubitemid 44572377)