-
1
-
-
79960605742
-
Altered sirtuin deacetylase gene expression in patients with a mood disorder
-
Abe N., Uchida S., Otsuki K., Hobara T., Yamagata H., Higuchi F., Shibata T., Watanabe Y. Altered sirtuin deacetylase gene expression in patients with a mood disorder. J.Psychiatr. Res. 2011, 45:1106-1112.
-
(2011)
J.Psychiatr. Res.
, vol.45
, pp. 1106-1112
-
-
Abe, N.1
Uchida, S.2
Otsuki, K.3
Hobara, T.4
Yamagata, H.5
Higuchi, F.6
Shibata, T.7
Watanabe, Y.8
-
3
-
-
68949206606
-
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide
-
Albani D., Polito L., Batelli S., De Mauro S., Fracasso C., Martelli G., Colombo L., Manzoni C., Salmona M., Caccia S., et al. The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide. J.Neurochem. 2009, 110:1445-1456.
-
(2009)
J.Neurochem.
, vol.110
, pp. 1445-1456
-
-
Albani, D.1
Polito, L.2
Batelli, S.3
De Mauro, S.4
Fracasso, C.5
Martelli, G.6
Colombo, L.7
Manzoni, C.8
Salmona, M.9
Caccia, S.10
-
4
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai T., Hasegawa M., Akiyama H., Ikeda K., Nonaka T., Mori H., Mann D., Tsuchiya K., Yoshida M., Hashizume Y., Oda T. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 2006, 351:602-611.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
5
-
-
84866103537
-
Sub-cellular localization, expression and functions of Sirt6 during the cell cycle in HeLa cells
-
Ardestani P.M., Liang F. Sub-cellular localization, expression and functions of Sirt6 during the cell cycle in HeLa cells. Nucleus 2012, 3:442-451.
-
(2012)
Nucleus
, vol.3
, pp. 442-451
-
-
Ardestani, P.M.1
Liang, F.2
-
6
-
-
47749140333
-
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
-
Asher G., Gatfield D., Stratmann M., Reinke H., Dibner C., Kreppel F., Mostoslavsky R., Alt F.W., Schibler U. SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell 2008, 134:317-328.
-
(2008)
Cell
, vol.134
, pp. 317-328
-
-
Asher, G.1
Gatfield, D.2
Stratmann, M.3
Reinke, H.4
Dibner, C.5
Kreppel, F.6
Mostoslavsky, R.7
Alt, F.W.8
Schibler, U.9
-
7
-
-
79953752384
-
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
-
Bai P., Cantó C., Oudart H., Brunyánszki A., Cen Y., Thomas C., Yamamoto H., Huber A., Kiss B., Houtkooper R.H., et al. PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell Metab. 2011, 13:461-468.
-
(2011)
Cell Metab.
, vol.13
, pp. 461-468
-
-
Bai, P.1
Cantó, C.2
Oudart, H.3
Brunyánszki, A.4
Cen, Y.5
Thomas, C.6
Yamamoto, H.7
Huber, A.8
Kiss, B.9
Houtkooper, R.H.10
-
8
-
-
84863453769
-
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
-
Barber M.F., Michishita-Kioi E., Xi Y., Tasselli L., Kioi M., Moqtaderi Z., Tennen R.I., Paredes S., Young N.L., Chen K., et al. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature 2012, 487:114-118.
-
(2012)
Nature
, vol.487
, pp. 114-118
-
-
Barber, M.F.1
Michishita-Kioi, E.2
Xi, Y.3
Tasselli, L.4
Kioi, M.5
Moqtaderi, Z.6
Tennen, R.I.7
Paredes, S.8
Young, N.L.9
Chen, K.10
-
9
-
-
84867414913
-
The time of metabolism: NAD+, SIRT1, and the circadian clock
-
Bellet M.M., Orozco-Solis R., Sahar S., Eckel-Mahan K., Sassone-Corsi P. The time of metabolism: NAD+, SIRT1, and the circadian clock. Cold Spring Harb. Symp. Quant. Biol. 2011, 76:31-38.
-
(2011)
Cold Spring Harb. Symp. Quant. Biol.
, vol.76
, pp. 31-38
-
-
Bellet, M.M.1
Orozco-Solis, R.2
Sahar, S.3
Eckel-Mahan, K.4
Sassone-Corsi, P.5
-
10
-
-
84874484700
-
Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1
-
Bellet M.M., Nakahata Y., Boudjelal M., Watts E., Mossakowska D.E., Edwards K.A., Cervantes M., Astarita G., Loh C., Ellis J.L., et al. Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1. Proc. Natl. Acad. Sci. USA 2013, 110:3333-3338.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 3333-3338
-
-
Bellet, M.M.1
Nakahata, Y.2
Boudjelal, M.3
Watts, E.4
Mossakowska, D.E.5
Edwards, K.A.6
Cervantes, M.7
Astarita, G.8
Loh, C.9
Ellis, J.L.10
-
11
-
-
77950968403
-
Neuron dysfunction is induced by prion protein with an insertional mutation via a Fyn kinase and reversed by sirtuin activation in Caenorhabditis elegans
-
Bizat N., Peyrin J.M., Haïk S., Cochois V., Beaudry P., Laplanche J.L., Néri C. Neuron dysfunction is induced by prion protein with an insertional mutation via a Fyn kinase and reversed by sirtuin activation in Caenorhabditis elegans. J.Neurosci. 2010, 30:5394-5403.
-
(2010)
J.Neurosci.
, vol.30
, pp. 5394-5403
-
-
Bizat, N.1
Peyrin, J.M.2
Haïk, S.3
Cochois, V.4
Beaudry, P.5
Laplanche, J.L.6
Néri, C.7
-
12
-
-
49849091089
-
Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice
-
Blanchet J., Longpré F., Bureau G., Morissette M., DiPaolo T., Bronchti G., Martinoli M.G. Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32:1243-1250.
-
(2008)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.32
, pp. 1243-1250
-
-
Blanchet, J.1
Longpré, F.2
Bureau, G.3
Morissette, M.4
DiPaolo, T.5
Bronchti, G.6
Martinoli, M.G.7
-
13
-
-
84859732716
-
Classic and new animal models of Parkinson's disease
-
Blesa J., Phani S., Jackson-Lewis V., Przedborski S. Classic and new animal models of Parkinson's disease. J.Biomed. Biotechnol. 2012, 2012:845618.
-
(2012)
J.Biomed. Biotechnol.
, vol.2012
, pp. 845618
-
-
Blesa, J.1
Phani, S.2
Jackson-Lewis, V.3
Przedborski, S.4
-
14
-
-
84896399265
-
Mapping NAD metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence
-
Published online December 17, 2013
-
Braidy N., Poljak A., Grant R., Jayasena T., Mansour H., Chan-Ling T., Guillemin G.J., Smythe G., Sachdev P. Mapping NAD metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence. Biogerontology 2013, Published online December 17, 2013. 10.1007/s10522-013-9489-5.
-
(2013)
Biogerontology
-
-
Braidy, N.1
Poljak, A.2
Grant, R.3
Jayasena, T.4
Mansour, H.5
Chan-Ling, T.6
Guillemin, G.J.7
Smythe, G.8
Sachdev, P.9
-
15
-
-
80052936278
-
Molecular mechanisms of androgen action-a historical perspective
-
Brinkmann A.O. Molecular mechanisms of androgen action-a historical perspective. Methods Mol. Biol. 2011, 776:3-24.
-
(2011)
Methods Mol. Biol.
, vol.776
, pp. 3-24
-
-
Brinkmann, A.O.1
-
16
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004, 303:2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
17
-
-
78650048197
-
Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells
-
Byles V., Chmilewski L.K., Wang J., Zhu L., Forman L.W., Faller D.V., Dai Y. Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells. Int. J. Biol. Sci. 2010, 6:599-612.
-
(2010)
Int. J. Biol. Sci.
, vol.6
, pp. 599-612
-
-
Byles, V.1
Chmilewski, L.K.2
Wang, J.3
Zhu, L.4
Forman, L.W.5
Faller, D.V.6
Dai, Y.7
-
18
-
-
77949506721
-
Hypothalamic Sirt1 regulates food intake in a rodent model system
-
Cakir I., Perello M., Lansari O., Messier N.J., Vaslet C.A., Nillni E.A. Hypothalamic Sirt1 regulates food intake in a rodent model system. PLoS ONE 2009, 4:e8322.
-
(2009)
PLoS ONE
, vol.4
-
-
Cakir, I.1
Perello, M.2
Lansari, O.3
Messier, N.J.4
Vaslet, C.A.5
Nillni, E.A.6
-
19
-
-
84862022077
-
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
-
Cantó C., Houtkooper R.H., Pirinen E., Youn D.Y., Oosterveer M.H., Cen Y., Fernandez-Marcos P.J., Yamamoto H., Andreux P.A., Cettour-Rose P., et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab. 2012, 15:838-847.
-
(2012)
Cell Metab.
, vol.15
, pp. 838-847
-
-
Cantó, C.1
Houtkooper, R.H.2
Pirinen, E.3
Youn, D.Y.4
Oosterveer, M.H.5
Cen, Y.6
Fernandez-Marcos, P.J.7
Yamamoto, H.8
Andreux, P.A.9
Cettour-Rose, P.10
-
20
-
-
84879391795
-
SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging
-
Chang H.C., Guarente L. SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging. Cell 2013, 153:1448-1460.
-
(2013)
Cell
, vol.153
, pp. 1448-1460
-
-
Chang, H.C.1
Guarente, L.2
-
21
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
-
Chen J., Zhou Y., Mueller-Steiner S., Chen L.F., Kwon H., Yi S., Mucke L., Gan L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J.Biol. Chem. 2005, 280:40364-40374.
-
(2005)
J.Biol. Chem.
, vol.280
, pp. 40364-40374
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
Chen, L.F.4
Kwon, H.5
Yi, S.6
Mucke, L.7
Gan, L.8
-
22
-
-
56349151227
-
The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration
-
Chen D., Steele A.D., Hutter G., Bruno J., Govindarajan A., Easlon E., Lin S.J., Aguzzi A., Lindquist S., Guarente L. The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration. Exp. Gerontol. 2008, 43:1086-1093.
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 1086-1093
-
-
Chen, D.1
Steele, A.D.2
Hutter, G.3
Bruno, J.4
Govindarajan, A.5
Easlon, E.6
Lin, S.J.7
Aguzzi, A.8
Lindquist, S.9
Guarente, L.10
-
23
-
-
84871706585
-
The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models
-
Chopra V., Quinti L., Kim J., Vollor L., Narayanan K.L., Edgerly C., Cipicchio P.M., Lauver M.A., Choi S.H., Silverman R.B., et al. The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models. Cell Rep 2012, 2:1492-1497.
-
(2012)
Cell Rep
, vol.2
, pp. 1492-1497
-
-
Chopra, V.1
Quinti, L.2
Kim, J.3
Vollor, L.4
Narayanan, K.L.5
Edgerly, C.6
Cipicchio, P.M.7
Lauver, M.A.8
Choi, S.H.9
Silverman, R.B.10
-
24
-
-
84867131638
-
SIRT1 regulates dendritic development in hippocampal neurons
-
Codocedo J.F., Allard C., Godoy J.A., Varela-Nallar L., Inestrosa N.C. SIRT1 regulates dendritic development in hippocampal neurons. PLoS One 2012, 7:e47073.
-
(2012)
PLoS One
, vol.7
-
-
Codocedo, J.F.1
Allard, C.2
Godoy, J.A.3
Varela-Nallar, L.4
Inestrosa, N.C.5
-
25
-
-
72849130743
-
Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction
-
Cohen D.E., Supinski A.M., Bonkowski M.S., Donmez G., Guarente L.P. Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction. Genes Dev. 2009, 23:2812-2817.
-
(2009)
Genes Dev.
, vol.23
, pp. 2812-2817
-
-
Cohen, D.E.1
Supinski, A.M.2
Bonkowski, M.S.3
Donmez, G.4
Guarente, L.P.5
-
26
-
-
79953087890
-
The acetylation of tau inhibits its function and promotes pathological tau aggregation
-
Cohen T.J., Guo J.L., Hurtado D.E., Kwong L.K., Mills I.P., Trojanowski J.Q., Lee V.M. The acetylation of tau inhibits its function and promotes pathological tau aggregation. Nat Commun 2011, 2:252.
-
(2011)
Nat Commun
, vol.2
, pp. 252
-
-
Cohen, T.J.1
Guo, J.L.2
Hurtado, D.E.3
Kwong, L.K.4
Mills, I.P.5
Trojanowski, J.Q.6
Lee, V.M.7
-
27
-
-
0142195765
-
Synergistic protection of PC12 cells from beta-amyloid toxicity by resveratrol and catechin
-
Conte A., Pellegrini S., Tagliazucchi D. Synergistic protection of PC12 cells from beta-amyloid toxicity by resveratrol and catechin. Brain Res. Bull. 2003, 62:29-38.
-
(2003)
Brain Res. Bull.
, vol.62
, pp. 29-38
-
-
Conte, A.1
Pellegrini, S.2
Tagliazucchi, D.3
-
28
-
-
84858750516
-
Metabolic actions of hypothalamic SIRT1
-
Coppari R. Metabolic actions of hypothalamic SIRT1. Trends Endocrinol. Metab. 2012, 23:179-185.
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 179-185
-
-
Coppari, R.1
-
29
-
-
84865654196
-
Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention
-
Cozzolino M., Pesaresi M.G., Gerbino V., Grosskreutz J., Carrì M.T. Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention. Antioxid. Redox Signal. 2012, 17:1277-1330.
-
(2012)
Antioxid. Redox Signal.
, vol.17
, pp. 1277-1330
-
-
Cozzolino, M.1
Pesaresi, M.G.2
Gerbino, V.3
Grosskreutz, J.4
Carrì, M.T.5
-
30
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
DeJesus-Hernandez M., Mackenzie I.R., Boeve B.F., Boxer A.L., Baker M., Rutherford N.J., Nicholson A.M., Finch N.A., Flynn H., Adamson J., et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011, 72:245-256.
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
DeJesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
Boxer, A.L.4
Baker, M.5
Rutherford, N.J.6
Nicholson, A.M.7
Finch, N.A.8
Flynn, H.9
Adamson, J.10
-
31
-
-
80052580969
-
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
-
Deng H.X., Chen W., Hong S.T., Boycott K.M., Gorrie G.H., Siddique N., Yang Y., Fecto F., Shi Y., Zhai H., et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature 2011, 477:211-215.
-
(2011)
Nature
, vol.477
, pp. 211-215
-
-
Deng, H.X.1
Chen, W.2
Hong, S.T.3
Boycott, K.M.4
Gorrie, G.H.5
Siddique, N.6
Yang, Y.7
Fecto, F.8
Shi, Y.9
Zhai, H.10
-
32
-
-
77956241193
-
Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity
-
Dietrich M.O., Antunes C., Geliang G., Liu Z.W., Borok E., Nie Y., Xu A.W., Souza D.O., Gao Q., Diano S., et al. Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity. J.Neurosci. 2010, 30:11815-11825.
-
(2010)
J.Neurosci.
, vol.30
, pp. 11815-11825
-
-
Dietrich, M.O.1
Antunes, C.2
Geliang, G.3
Liu, Z.W.4
Borok, E.5
Nie, Y.6
Xu, A.W.7
Souza, D.O.8
Gao, Q.9
Diano, S.10
-
33
-
-
84864474183
-
AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors
-
Dietrich M.O., Bober J., Ferreira J.G., Tellez L.A., Mineur Y.S., Souza D.O., Gao X.B., Picciotto M.R., Araújo I., Liu Z.W., Horvath T.L. AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors. Nat. Neurosci. 2012, 15:1108-1110.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 1108-1110
-
-
Dietrich, M.O.1
Bober, J.2
Ferreira, J.G.3
Tellez, L.A.4
Mineur, Y.S.5
Souza, D.O.6
Gao, X.B.7
Picciotto, M.R.8
Araújo, I.9
Liu, Z.W.10
Horvath, T.L.11
-
34
-
-
36048958965
-
Histone deacetylase inhibitors: overview and perspectives
-
Dokmanovic M., Clarke C., Marks P.A. Histone deacetylase inhibitors: overview and perspectives. Mol. Cancer Res. 2007, 5:981-989.
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 981-989
-
-
Dokmanovic, M.1
Clarke, C.2
Marks, P.A.3
-
35
-
-
77955046461
-
SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
-
Donmez G., Wang D., Cohen D.E., Guarente L. SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell 2010, 142:320-332.
-
(2010)
Cell
, vol.142
, pp. 320-332
-
-
Donmez, G.1
Wang, D.2
Cohen, D.E.3
Guarente, L.4
-
36
-
-
84855929223
-
SIRT1 protects against α-synuclein aggregation by activating molecular chaperones
-
Donmez G., Arun A., Chung C.Y., McLean P.J., Lindquist S., Guarente L. SIRT1 protects against α-synuclein aggregation by activating molecular chaperones. J.Neurosci. 2012, 32:124-132.
-
(2012)
J.Neurosci.
, vol.32
, pp. 124-132
-
-
Donmez, G.1
Arun, A.2
Chung, C.Y.3
McLean, P.J.4
Lindquist, S.5
Guarente, L.6
-
37
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
-
Du J., Zhou Y., Su X., Yu J.J., Khan S., Jiang H., Kim J., Woo J., Kim J.H., Choi B.H., et al. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science 2011, 334:806-809.
-
(2011)
Science
, vol.334
, pp. 806-809
-
-
Du, J.1
Zhou, Y.2
Su, X.3
Yu, J.J.4
Khan, S.5
Jiang, H.6
Kim, J.7
Woo, J.8
Kim, J.H.9
Choi, B.H.10
-
38
-
-
84881034102
-
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection
-
Eskandarian H.A., Impens F., Nahori M.A., Soubigou G., Coppée J.Y., Cossart P., Hamon M.A. A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection. Science 2013, 341:1238858.
-
(2013)
Science
, vol.341
, pp. 1238858
-
-
Eskandarian, H.A.1
Impens, F.2
Nahori, M.A.3
Soubigou, G.4
Coppée, J.Y.5
Cossart, P.6
Hamon, M.A.7
-
39
-
-
84885156997
-
Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action
-
Ferguson D., Koo J.W., Feng J., Heller E., Rabkin J., Heshmati M., Renthal W., Neve R., Liu X., Shao N., et al. Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action. J.Neurosci. 2013, 33:16088-16098.
-
(2013)
J.Neurosci.
, vol.33
, pp. 16088-16098
-
-
Ferguson, D.1
Koo, J.W.2
Feng, J.3
Heller, E.4
Rabkin, J.5
Heshmati, M.6
Renthal, W.7
Neve, R.8
Liu, X.9
Shao, N.10
-
40
-
-
78751590932
-
Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial
-
Fernández-Rhodes L.E., Kokkinis A.D., White M.J., Watts C.A., Auh S., Jeffries N.O., Shrader J.A., Lehky T.J., Li L., Ryder J.E., et al. Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial. Lancet Neurol. 2011, 10:140-147.
-
(2011)
Lancet Neurol.
, vol.10
, pp. 140-147
-
-
Fernández-Rhodes, L.E.1
Kokkinis, A.D.2
White, M.J.3
Watts, C.A.4
Auh, S.5
Jeffries, N.O.6
Shrader, J.A.7
Lehky, T.J.8
Li, L.9
Ryder, J.E.10
-
41
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Ferrante R.J., Browne S.E., Shinobu L.A., Bowling A.C., Baik M.J., MacGarvey U., Kowall N.W., Brown R.H., Beal M.F. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J.Neurochem. 1997, 69:2064-2074.
-
(1997)
J.Neurochem.
, vol.69
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
MacGarvey, U.6
Kowall, N.W.7
Brown, R.H.8
Beal, M.F.9
-
42
-
-
84865851734
-
Resveratrol neuroprotection in a chronic mouse model of multiple sclerosis
-
Fonseca-Kelly Z., Nassrallah M., Uribe J., Khan R.S., Dine K., Dutt M., Shindler K.S. Resveratrol neuroprotection in a chronic mouse model of multiple sclerosis. Front. Neurol. 2012, 3:84.
-
(2012)
Front. Neurol.
, vol.3
, pp. 84
-
-
Fonseca-Kelly, Z.1
Nassrallah, M.2
Uribe, J.3
Khan, R.S.4
Dine, K.5
Dutt, M.6
Shindler, K.S.7
-
43
-
-
33744466971
-
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
-
Ford E., Voit R., Liszt G., Magin C., Grummt I., Guarente L. Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev. 2006, 20:1075-1080.
-
(2006)
Genes Dev.
, vol.20
, pp. 1075-1080
-
-
Ford, E.1
Voit, R.2
Liszt, G.3
Magin, C.4
Grummt, I.5
Guarente, L.6
-
44
-
-
0033600176
-
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
-
Frye R.A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 1999, 260:273-279.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.260
, pp. 273-279
-
-
Frye, R.A.1
-
45
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
Frye R.A. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem. Biophys. Res. Commun. 2000, 273:793-798.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
46
-
-
33750367457
-
Hormonal control of androgen receptor function through SIRT1
-
Fu M., Liu M., Sauve A.A., Jiao X., Zhang X., Wu X., Powell M.J., Yang T., Gu W., Avantaggiati M.L., et al. Hormonal control of androgen receptor function through SIRT1. Mol. Cell. Biol. 2006, 26:8122-8135.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 8122-8135
-
-
Fu, M.1
Liu, M.2
Sauve, A.A.3
Jiao, X.4
Zhang, X.5
Wu, X.6
Powell, M.J.7
Yang, T.8
Gu, W.9
Avantaggiati, M.L.10
-
47
-
-
77956185062
-
A novel pathway regulates memory and plasticity via SIRT1 and miR-134
-
Gao J., Wang W.Y., Mao Y.W., Gräff J., Guan J.S., Pan L., Mak G., Kim D., Su S.C., Tsai L.H. A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 2010, 466:1105-1109.
-
(2010)
Nature
, vol.466
, pp. 1105-1109
-
-
Gao, J.1
Wang, W.Y.2
Mao, Y.W.3
Gräff, J.4
Guan, J.S.5
Pan, L.6
Mak, G.7
Kim, D.8
Su, S.C.9
Tsai, L.H.10
-
48
-
-
84893442805
-
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
-
Gomes A.P., Price N.L., Ling A.J., Moslehi J.J., Montgomery M.K., Rajman L., White J.P., Teodoro J.S., Wrann C.D., Hubbard B.P., et al. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell 2013, 155:1624-1638.
-
(2013)
Cell
, vol.155
, pp. 1624-1638
-
-
Gomes, A.P.1
Price, N.L.2
Ling, A.J.3
Moslehi, J.J.4
Montgomery, M.K.5
Rajman, L.6
White, J.P.7
Teodoro, J.S.8
Wrann, C.D.9
Hubbard, B.P.10
-
49
-
-
1842578986
-
Molecular evolution ofthe histone deacetylase family: functional implications of phylogenetic analysis
-
Gregoretti I.V., Lee Y.M., Goodson H.V. Molecular evolution ofthe histone deacetylase family: functional implications of phylogenetic analysis. J.Mol. Biol. 2004, 338:17-31.
-
(2004)
J.Mol. Biol.
, vol.338
, pp. 17-31
-
-
Gregoretti, I.V.1
Lee, Y.M.2
Goodson, H.V.3
-
50
-
-
84885355365
-
Calorie restriction and sirtuins revisited
-
Guarente L. Calorie restriction and sirtuins revisited. Genes Dev. 2013, 27:2072-2085.
-
(2013)
Genes Dev.
, vol.27
, pp. 2072-2085
-
-
Guarente, L.1
-
51
-
-
80052645243
-
Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling
-
Guo W., Qian L., Zhang J., Zhang W., Morrison A., Hayes P., Wilson S., Chen T., Zhao J. Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling. J.Neurosci. Res. 2011, 89:1723-1736.
-
(2011)
J.Neurosci. Res.
, vol.89
, pp. 1723-1736
-
-
Guo, W.1
Qian, L.2
Zhang, J.3
Zhang, W.4
Morrison, A.5
Hayes, P.6
Wilson, S.7
Chen, T.8
Zhao, J.9
-
52
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
-
Haigis M.C., Mostoslavsky R., Haigis K.M., Fahie K., Christodoulou D.C., Murphy A.J., Valenzuela D.M., Yancopoulos G.D., Karow M., Blander G., et al. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 2006, 126:941-954.
-
(2006)
Cell
, vol.126
, pp. 941-954
-
-
Haigis, M.C.1
Mostoslavsky, R.2
Haigis, K.M.3
Fahie, K.4
Christodoulou, D.C.5
Murphy, A.J.6
Valenzuela, D.M.7
Yancopoulos, G.D.8
Karow, M.9
Blander, G.10
-
53
-
-
1942472491
-
Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C
-
Han Y.S., Zheng W.H., Bastianetto S., Chabot J.G., Quirion R. Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C. Br. J. Pharmacol. 2004, 141:997-1005.
-
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 997-1005
-
-
Han, Y.S.1
Zheng, W.H.2
Bastianetto, S.3
Chabot, J.G.4
Quirion, R.5
-
54
-
-
84867581334
-
Resveratrol upregulated heat shock proteins and extended the survival of G93A-SOD1 mice
-
Han S., Choi J.R., Soon Shin K., Kang S.J. Resveratrol upregulated heat shock proteins and extended the survival of G93A-SOD1 mice. Brain Res. 2012, 1483:112-117.
-
(2012)
Brain Res.
, vol.1483
, pp. 112-117
-
-
Han, S.1
Choi, J.R.2
Soon Shin, K.3
Kang, S.J.4
-
55
-
-
78349291479
-
Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease
-
Hathorn T., Snyder-Keller A., Messer A. Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease. Neurobiol. Dis. 2011, 41:43-50.
-
(2011)
Neurobiol. Dis.
, vol.41
, pp. 43-50
-
-
Hathorn, T.1
Snyder-Keller, A.2
Messer, A.3
-
56
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
Hirschey M.D., Shimazu T., Goetzman E., Jing E., Schwer B., Lombard D.B., Grueter C.A., Harris C., Biddinger S., Ilkayeva O.R., et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 2010, 464:121-125.
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
-
57
-
-
55749095213
-
Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
-
Hisahara S., Chiba S., Matsumoto H., Tanno M., Yagi H., Shimohama S., Sato M., Horio Y. Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. Proc. Natl. Acad. Sci. USA 2008, 105:15599-15604.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15599-15604
-
-
Hisahara, S.1
Chiba, S.2
Matsumoto, H.3
Tanno, M.4
Yagi, H.5
Shimohama, S.6
Sato, M.7
Horio, Y.8
-
58
-
-
77955660387
-
Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease
-
Ho D.J., Calingasan N.Y., Wille E., Dumont M., Beal M.F. Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease. Exp. Neurol. 2010, 225:74-84.
-
(2010)
Exp. Neurol.
, vol.225
, pp. 74-84
-
-
Ho, D.J.1
Calingasan, N.Y.2
Wille, E.3
Dumont, M.4
Beal, M.F.5
-
59
-
-
84866152559
-
Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals
-
Hong S.H., Lee K.S., Kwak S.J., Kim A.K., Bai H., Jung M.S., Kwon O.Y., Song W.J., Tatar M., Yu K. Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals. PLoS Genet. 2012, 8:e1002857.
-
(2012)
PLoS Genet.
, vol.8
-
-
Hong, S.H.1
Lee, K.S.2
Kwak, S.J.3
Kim, A.K.4
Bai, H.5
Jung, M.S.6
Kwon, O.Y.7
Song, W.J.8
Tatar, M.9
Yu, K.10
-
60
-
-
84874721105
-
Evidence for a common mechanism of SIRT1 regulation by allosteric activators
-
Hubbard B.P., Gomes A.P., Dai H., Li J., Case A.W., Considine T., Riera T.V., Lee J.E., e S.Y., Lamming D.W., et al. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science 2013, 339:1216-1219.
-
(2013)
Science
, vol.339
, pp. 1216-1219
-
-
Hubbard, B.P.1
Gomes, A.P.2
Dai, H.3
Li, J.4
Case, A.W.5
Considine, T.6
Riera, T.V.7
Lee, J.E.8
e, S.Y.9
Lamming, D.W.10
-
61
-
-
84865345111
-
Prognostic significance of sirtuin 2 protein nuclear localization in glioma: an immunohistochemical study
-
Imaoka N., Hiratsuka M., Osaki M., Kamitani H., Kambe A., Fukuoka J., Kurimoto M., Nagai S., Okada F., Watanabe T., et al. Prognostic significance of sirtuin 2 protein nuclear localization in glioma: an immunohistochemical study. Oncol. Rep. 2012, 28:923-930.
-
(2012)
Oncol. Rep.
, vol.28
, pp. 923-930
-
-
Imaoka, N.1
Hiratsuka, M.2
Osaki, M.3
Kamitani, H.4
Kambe, A.5
Fukuoka, J.6
Kurimoto, M.7
Nagai, S.8
Okada, F.9
Watanabe, T.10
-
62
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S., Armstrong C.M., Kaeberlein M., Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000, 403:795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
63
-
-
0037446328
-
Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death
-
Jang J.H., Surh Y.J. Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death. Free Radic. Biol. Med. 2003, 34:1100-1110.
-
(2003)
Free Radic. Biol. Med.
, vol.34
, pp. 1100-1110
-
-
Jang, J.H.1
Surh, Y.J.2
-
64
-
-
84855563516
-
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
-
Jeong H., Cohen D.E., Cui L., Supinski A., Savas J.N., Mazzulli J.R., Yates J.R., Bordone L., Guarente L., Krainc D. Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. Nat. Med. 2012, 18:159-165.
-
(2012)
Nat. Med.
, vol.18
, pp. 159-165
-
-
Jeong, H.1
Cohen, D.E.2
Cui, L.3
Supinski, A.4
Savas, J.N.5
Mazzulli, J.R.6
Yates, J.R.7
Bordone, L.8
Guarente, L.9
Krainc, D.10
-
65
-
-
84868139191
-
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
-
Jeong J.K., Moon M.H., Lee Y.J., Seol J.W., Park S.Y. Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity. Neurobiol. Aging 2013, 34:146-156.
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 146-156
-
-
Jeong, J.K.1
Moon, M.H.2
Lee, Y.J.3
Seol, J.W.4
Park, S.Y.5
-
66
-
-
84875881601
-
SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine
-
Jiang H., Khan S., Wang Y., Charron G., He B., Sebastian C., Du J., Kim R., Ge E., Mostoslavsky R., et al. SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine. Nature 2013, 496:110-113.
-
(2013)
Nature
, vol.496
, pp. 110-113
-
-
Jiang, H.1
Khan, S.2
Wang, Y.3
Charron, G.4
He, B.5
Sebastian, C.6
Du, J.7
Kim, R.8
Ge, E.9
Mostoslavsky, R.10
-
67
-
-
84855544817
-
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
-
Jiang M., Wang J., Fu J., Du L., Jeong H., West T., Xiang L., Peng Q., Hou Z., Cai H., et al. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat. Med. 2012, 18:153-158.
-
(2012)
Nat. Med.
, vol.18
, pp. 153-158
-
-
Jiang, M.1
Wang, J.2
Fu, J.3
Du, L.4
Jeong, H.5
West, T.6
Xiang, L.7
Peng, Q.8
Hou, Z.9
Cai, H.10
-
68
-
-
34548471739
-
Cytoplasm-localized SIRT1 enhances apoptosis
-
Jin Q., Yan T., Ge X., Sun C., Shi X., Zhai Q. Cytoplasm-localized SIRT1 enhances apoptosis. J.Cell. Physiol. 2007, 213:88-97.
-
(2007)
J.Cell. Physiol.
, vol.213
, pp. 88-97
-
-
Jin, Q.1
Yan, T.2
Ge, X.3
Sun, C.4
Shi, X.5
Zhai, Q.6
-
69
-
-
78649941297
-
Exome sequencing reveals VCP mutations as a cause of familial ALS
-
ITALSGEN Consortium
-
Johnson J.O., Mandrioli J., Benatar M., Abramzon Y., Van Deerlin V.M., Trojanowski J.Q., Gibbs J.R., Brunetti M., Gronka S., Wuu J., et al. Exome sequencing reveals VCP mutations as a cause of familial ALS. Neuron 2010, 68:857-864. ITALSGEN Consortium.
-
(2010)
Neuron
, vol.68
, pp. 857-864
-
-
Johnson, J.O.1
Mandrioli, J.2
Benatar, M.3
Abramzon, Y.4
Van Deerlin, V.M.5
Trojanowski, J.Q.6
Gibbs, J.R.7
Brunetti, M.8
Gronka, S.9
Wuu, J.10
-
70
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein M., McVey M., Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 1999, 13:2570-2580.
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
71
-
-
60249098801
-
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
-
Karuppagounder S.S., Pinto J.T., Xu H., Chen H.L., Beal M.F., Gibson G.E. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem. Int. 2009, 54:111-118.
-
(2009)
Neurochem. Int.
, vol.54
, pp. 111-118
-
-
Karuppagounder, S.S.1
Pinto, J.T.2
Xu, H.3
Chen, H.L.4
Beal, M.F.5
Gibson, G.E.6
-
72
-
-
18644379256
-
Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
-
Katsuno M., Adachi H., Kume A., Li M., Nakagomi Y., Niwa H., Sang C., Kobayashi Y., Doyu M., Sobue G. Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy. Neuron 2002, 35:843-854.
-
(2002)
Neuron
, vol.35
, pp. 843-854
-
-
Katsuno, M.1
Adachi, H.2
Kume, A.3
Li, M.4
Nakagomi, Y.5
Niwa, H.6
Sang, C.7
Kobayashi, Y.8
Doyu, M.9
Sobue, G.10
-
73
-
-
0038714285
-
Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy
-
Katsuno M., Adachi H., Doyu M., Minamiyama M., Sang C., Kobayashi Y., Inukai A., Sobue G. Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy. Nat. Med. 2003, 9:768-773.
-
(2003)
Nat. Med.
, vol.9
, pp. 768-773
-
-
Katsuno, M.1
Adachi, H.2
Doyu, M.3
Minamiyama, M.4
Sang, C.5
Kobayashi, Y.6
Inukai, A.7
Sobue, G.8
-
74
-
-
77955662063
-
Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial
-
Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group
-
Katsuno M., Banno H., Suzuki K., Takeuchi Y., Kawashima M., Yabe I., Sasaki H., Aoki M., Morita M., Nakano I., et al. Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2010, 9:875-884. Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group.
-
(2010)
Lancet Neurol.
, vol.9
, pp. 875-884
-
-
Katsuno, M.1
Banno, H.2
Suzuki, K.3
Takeuchi, Y.4
Kawashima, M.5
Yabe, I.6
Sasaki, H.7
Aoki, M.8
Morita, M.9
Nakano, I.10
-
75
-
-
0032831936
-
Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae
-
Kim S., Benguria A., Lai C.Y., Jazwinski S.M. Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol. Biol. Cell 1999, 10:3125-3136.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3125-3136
-
-
Kim, S.1
Benguria, A.2
Lai, C.Y.3
Jazwinski, S.M.4
-
76
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim D., Nguyen M.D., Dobbin M.M., Fischer A., Sananbenesi F., Rodgers J.T., Delalle I., Baur J.A., Sui G., Armour S.M., et al. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 2007, 26:3169-3179.
-
(2007)
EMBO J.
, vol.26
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
Delalle, I.7
Baur, J.A.8
Sui, G.9
Armour, S.M.10
-
77
-
-
77956268388
-
SIRT1 gene is associated with major depressive disorder in the Japanese population
-
Kishi T., Yoshimura R., Kitajima T., Okochi T., Okumura T., Tsunoka T., Yamanouchi Y., Kinoshita Y., Kawashima K., Fukuo Y., et al. SIRT1 gene is associated with major depressive disorder in the Japanese population. J.Affect. Disord. 2010, 126:167-173.
-
(2010)
J.Affect. Disord.
, vol.126
, pp. 167-173
-
-
Kishi, T.1
Yoshimura, R.2
Kitajima, T.3
Okochi, T.4
Okumura, T.5
Tsunoka, T.6
Yamanouchi, Y.7
Kinoshita, Y.8
Kawashima, K.9
Fukuo, Y.10
-
78
-
-
79953276539
-
SIRT1 gene, schizophrenia and bipolar disorder in the Japanese population: an association study
-
Kishi T., Fukuo Y., Kitajima T., Okochi T., Yamanouchi Y., Kinoshita Y., Kawashima K., Inada T., Kunugi H., Kato T., et al. SIRT1 gene, schizophrenia and bipolar disorder in the Japanese population: an association study. Genes Brain Behav. 2011, 10:257-263.
-
(2011)
Genes Brain Behav.
, vol.10
, pp. 257-263
-
-
Kishi, T.1
Fukuo, Y.2
Kitajima, T.3
Okochi, T.4
Yamanouchi, Y.5
Kinoshita, Y.6
Kawashima, K.7
Inada, T.8
Kunugi, H.9
Kato, T.10
-
79
-
-
80755189063
-
No significant association between SIRT1 gene and methamphetamine-induced psychosis in the Japanese population
-
Kishi T., Fukuo Y., Okochi T., Kitajima T., Ujike H., Inada T., Yamada M., Uchimura N., Sora I., Iyo M., et al. No significant association between SIRT1 gene and methamphetamine-induced psychosis in the Japanese population. Hum. Psychopharmacol. 2011, 26:445-450.
-
(2011)
Hum. Psychopharmacol.
, vol.26
, pp. 445-450
-
-
Kishi, T.1
Fukuo, Y.2
Okochi, T.3
Kitajima, T.4
Ujike, H.5
Inada, T.6
Yamada, M.7
Uchimura, N.8
Sora, I.9
Iyo, M.10
-
80
-
-
0018644035
-
MAR1-a Regulator of the HMa and HMalpha Loci in SACCHAROMYCES CEREVISIAE
-
Klar A.J., Fogel S., Macleod K. MAR1-a Regulator of the HMa and HMalpha Loci in SACCHAROMYCES CEREVISIAE. Genetics 1979, 93:37-50.
-
(1979)
Genetics
, vol.93
, pp. 37-50
-
-
Klar, A.J.1
Fogel, S.2
Macleod, K.3
-
81
-
-
84873096554
-
Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?
-
Körner S., Böselt S., Thau N., Rath K.J., Dengler R., Petri S. Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?. Neurodegener. Dis. 2013, 11:141-152.
-
(2013)
Neurodegener. Dis.
, vol.11
, pp. 141-152
-
-
Körner, S.1
Böselt, S.2
Thau, N.3
Rath, K.J.4
Dengler, R.5
Petri, S.6
-
82
-
-
84875543467
-
The current and projected economic burden of Parkinson's disease in the United States
-
Kowal S.L., Dall T.M., Chakrabarti R., Storm M.V., Jain A. The current and projected economic burden of Parkinson's disease in the United States. Mov. Disord. 2013, 28:311-318.
-
(2013)
Mov. Disord.
, vol.28
, pp. 311-318
-
-
Kowal, S.L.1
Dall, T.M.2
Chakrabarti, R.3
Storm, M.V.4
Jain, A.5
-
83
-
-
33748310632
-
Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms
-
Kumar P., Padi S.S., Naidu P.S., Kumar A. Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms. Behav. Pharmacol. 2006, 17:485-492.
-
(2006)
Behav. Pharmacol.
, vol.17
, pp. 485-492
-
-
Kumar, P.1
Padi, S.S.2
Naidu, P.S.3
Kumar, A.4
-
84
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski T.J., Bosco D.A., Leclerc A.L., Tamrazian E., Vanderburg C.R., Russ C., Davis A., Gilchrist J., Kasarskis E.J., Munsat T., et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009, 323:1205-1208.
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski, T.J.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
Davis, A.7
Gilchrist, J.8
Kasarskis, E.J.9
Munsat, T.10
-
85
-
-
84855519786
-
Finding a sirtuin truth in Huntington's disease
-
La Spada A.R. Finding a sirtuin truth in Huntington's disease. Nat. Med. 2012, 18:24-26.
-
(2012)
Nat. Med.
, vol.18
, pp. 24-26
-
-
La Spada, A.R.1
-
86
-
-
0025800526
-
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
-
La Spada A.R., Wilson E.M., Lubahn D.B., Harding A.E., Fischbeck K.H. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 1991, 352:77-79.
-
(1991)
Nature
, vol.352
, pp. 77-79
-
-
La Spada, A.R.1
Wilson, E.M.2
Lubahn, D.B.3
Harding, A.E.4
Fischbeck, K.H.5
-
87
-
-
0034705129
-
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
-
Landry J., Sutton A., Tafrov S.T., Heller R.C., Stebbins J., Pillus L., Sternglanz R. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc. Natl. Acad. Sci. USA 2000, 97:5807-5811.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
Heller, R.C.4
Stebbins, J.5
Pillus, L.6
Sternglanz, R.7
-
88
-
-
84855200886
-
Region-specific changes in the immunoreactivity of SIRT1 expression in the central nervous system of SOD1(G93A) transgenic mice as an invivo model of amyotrophic lateral sclerosis
-
Lee J.C., Shin J.H., Park B.W., Kim G.S., Kim J.C., Kang K.S., Cha C.I. Region-specific changes in the immunoreactivity of SIRT1 expression in the central nervous system of SOD1(G93A) transgenic mice as an invivo model of amyotrophic lateral sclerosis. Brain Res. 2012, 1433:20-28.
-
(2012)
Brain Res.
, vol.1433
, pp. 20-28
-
-
Lee, J.C.1
Shin, J.H.2
Park, B.W.3
Kim, G.S.4
Kim, J.C.5
Kang, K.S.6
Cha, C.I.7
-
89
-
-
84888004300
-
Sirt1 promotes axonogenesis by deacetylation of Akt and inactivation of GSK3
-
Li X.H., Chen C., Tu Y., Sun H.T., Zhao M.L., Cheng S.X., Qu Y., Zhang S. Sirt1 promotes axonogenesis by deacetylation of Akt and inactivation of GSK3. Mol. Neurobiol. 2013, 48:490-499.
-
(2013)
Mol. Neurobiol.
, vol.48
, pp. 490-499
-
-
Li, X.H.1
Chen, C.2
Tu, Y.3
Sun, H.T.4
Zhao, M.L.5
Cheng, S.X.6
Qu, Y.7
Zhang, S.8
-
90
-
-
84455169414
-
SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive
-
Libert S., Pointer K., Bell E.L., Das A., Cohen D.E., Asara J.M., Kapur K., Bergmann S., Preisig M., Otowa T., et al. SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive. Cell 2011, 147:1459-1472.
-
(2011)
Cell
, vol.147
, pp. 1459-1472
-
-
Libert, S.1
Pointer, K.2
Bell, E.L.3
Das, A.4
Cohen, D.E.5
Asara, J.M.6
Kapur, K.7
Bergmann, S.8
Preisig, M.9
Otowa, T.10
-
91
-
-
20444409132
-
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
-
Liszt G., Ford E., Kurtev M., Guarente L. Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase. J.Biol. Chem. 2005, 280:21313-21320.
-
(2005)
J.Biol. Chem.
, vol.280
, pp. 21313-21320
-
-
Liszt, G.1
Ford, E.2
Kurtev, M.3
Guarente, L.4
-
92
-
-
84879747965
-
MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration
-
Liu C.M., Wang R.Y., Saijilafu, Jiao Z.X., Zhang B.Y., Zhou F.Q. MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration. Genes Dev. 2013, 27:1473-1483.
-
(2013)
Genes Dev.
, vol.27
, pp. 1473-1483
-
-
Liu, C.M.1
Wang, R.Y.2
Saijilafu3
Jiao, Z.X.4
Zhang, B.Y.5
Zhou, F.Q.6
-
93
-
-
77956561879
-
A single-dose resveratrol treatment in a mouse model of amyotrophic lateral sclerosis
-
Markert C.D., Kim E., Gifondorwa D.J., Childers M.K., Milligan C.E. A single-dose resveratrol treatment in a mouse model of amyotrophic lateral sclerosis. J.Med. Food 2010, 13:1081-1085.
-
(2010)
J.Med. Food
, vol.13
, pp. 1081-1085
-
-
Markert, C.D.1
Kim, E.2
Gifondorwa, D.J.3
Childers, M.K.4
Milligan, C.E.5
-
94
-
-
84864401965
-
Age-associated changes in oxidative stress and NAD+ metabolism in human tissue
-
Massudi H., Grant R., Braidy N., Guest J., Farnsworth B., Guillemin G.J. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS ONE 2012, 7:e42357.
-
(2012)
PLoS ONE
, vol.7
-
-
Massudi, H.1
Grant, R.2
Braidy, N.3
Guest, J.4
Farnsworth, B.5
Guillemin, G.J.6
-
95
-
-
84876032463
-
Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses
-
Matarese G., Procaccini C., Menale C., Kim J.G., Kim J.D., Diano S., Diano N., De Rosa V., Dietrich M.O., Horvath T.L. Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses. Proc. Natl. Acad. Sci. USA 2013, 110:6193-6198.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 6193-6198
-
-
Matarese, G.1
Procaccini, C.2
Menale, C.3
Kim, J.G.4
Kim, J.D.5
Diano, S.6
Diano, N.7
De Rosa, V.8
Dietrich, M.O.9
Horvath, T.L.10
-
96
-
-
84870288862
-
Attacking the flank: targeting new pathways in SBMA
-
Merry D.E. Attacking the flank: targeting new pathways in SBMA. Nat. Med. 2012, 18:1461-1463.
-
(2012)
Nat. Med.
, vol.18
, pp. 1461-1463
-
-
Merry, D.E.1
-
97
-
-
77954855825
-
SIRT1 is essential for normal cognitive function and synaptic plasticity
-
Michán S., Li Y., Chou M.M., Parrella E., Ge H., Long J.M., Allard J.S., Lewis K., Miller M., Xu W., et al. SIRT1 is essential for normal cognitive function and synaptic plasticity. J.Neurosci. 2010, 30:9695-9707.
-
(2010)
J.Neurosci.
, vol.30
, pp. 9695-9707
-
-
Michán, S.1
Li, Y.2
Chou, M.M.3
Parrella, E.4
Ge, H.5
Long, J.M.6
Allard, J.S.7
Lewis, K.8
Miller, M.9
Xu, W.10
-
98
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
Michishita E., McCord R.A., Berber E., Kioi M., Padilla-Nash H., Damian M., Cheung P., Kusumoto R., Kawahara T.L., Barrett J.C., et al. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 2008, 452:492-496.
-
(2008)
Nature
, vol.452
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.9
Barrett, J.C.10
-
99
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
Michishita E., Park J.Y., Burneskis J.M., Barrett J.C., Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Biol. Cell 2005, 16:4623-4635.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
100
-
-
77957001697
-
Acetylation of tau inhibits its degradation and contributes to tauopathy
-
Min S.W., Cho S.H., Zhou Y., Schroeder S., Haroutunian V., Seeley W.W., Huang E.J., Shen Y., Masliah E., Mukherjee C., et al. Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron 2010, 67:953-966.
-
(2010)
Neuron
, vol.67
, pp. 953-966
-
-
Min, S.W.1
Cho, S.H.2
Zhou, Y.3
Schroeder, S.4
Haroutunian, V.5
Seeley, W.W.6
Huang, E.J.7
Shen, Y.8
Masliah, E.9
Mukherjee, C.10
-
101
-
-
82555200920
-
SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA
-
Montie H.L., Pestell R.G., Merry D.E. SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA. J.Neurosci. 2011, 31:17425-17436.
-
(2011)
J.Neurosci.
, vol.31
, pp. 17425-17436
-
-
Montie, H.L.1
Pestell, R.G.2
Merry, D.E.3
-
102
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
Mostoslavsky R., Chua K.F., Lombard D.B., Pang W.W., Fischer M.R., Gellon L., Liu P., Mostoslavsky G., Franco S., Murphy M.M., et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 2006, 124:315-329.
-
(2006)
Cell
, vol.124
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
-
103
-
-
84880517634
-
The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
-
Mouchiroud L., Houtkooper R.H., Moullan N., Katsyuba E., Ryu D., Cantó C., Mottis A., Jo Y.S., Viswanathan M., Schoonjans K., et al. The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling. Cell 2013, 154:430-441.
-
(2013)
Cell
, vol.154
, pp. 430-441
-
-
Mouchiroud, L.1
Houtkooper, R.H.2
Moullan, N.3
Katsyuba, E.4
Ryu, D.5
Cantó, C.6
Mottis, A.7
Jo, Y.S.8
Viswanathan, M.9
Schoonjans, K.10
-
104
-
-
84859159081
-
Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease
-
Mudò G., Mäkelä J., Di Liberto V., Tselykh T.V., Olivieri M., Piepponen P., Eriksson O., Mälkiä A., Bonomo A., Kairisalo M., et al. Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease. Cell. Mol. Life Sci. 2012, 69:1153-1165.
-
(2012)
Cell. Mol. Life Sci.
, vol.69
, pp. 1153-1165
-
-
Mudò, G.1
Mäkelä, J.2
Di Liberto, V.3
Tselykh, T.V.4
Olivieri, M.5
Piepponen, P.6
Eriksson, O.7
Mälkiä, A.8
Bonomo, A.9
Kairisalo, M.10
-
105
-
-
84890015150
-
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
-
Musiek E.S., Lim M.M., Yang G., Bauer A.Q., Qi L., Lee Y., Roh J.H., Ortiz-Gonzalez X., Dearborn J.T., Culver J.P., et al. Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. J.Clin. Invest. 2013, 123:5389-5400.
-
(2013)
J.Clin. Invest.
, vol.123
, pp. 5389-5400
-
-
Musiek, E.S.1
Lim, M.M.2
Yang, G.3
Bauer, A.Q.4
Qi, L.5
Lee, Y.6
Roh, J.H.7
Ortiz-Gonzalez, X.8
Dearborn, J.T.9
Culver, J.P.10
-
106
-
-
65249087389
-
SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle
-
Nakagawa T., Lomb D.J., Haigis M.C., Guarente L. SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle. Cell 2009, 137:560-570.
-
(2009)
Cell
, vol.137
, pp. 560-570
-
-
Nakagawa, T.1
Lomb, D.J.2
Haigis, M.C.3
Guarente, L.4
-
107
-
-
47549088250
-
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
-
Nakahata Y., Kaluzova M., Grimaldi B., Sahar S., Hirayama J., Chen D., Guarente L.P., Sassone-Corsi P. The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell 2008, 134:329-340.
-
(2008)
Cell
, vol.134
, pp. 329-340
-
-
Nakahata, Y.1
Kaluzova, M.2
Grimaldi, B.3
Sahar, S.4
Hirayama, J.5
Chen, D.6
Guarente, L.P.7
Sassone-Corsi, P.8
-
108
-
-
65549118773
-
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1
-
Nakahata Y., Sahar S., Astarita G., Kaluzova M., Sassone-Corsi P. Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science 2009, 324:654-657.
-
(2009)
Science
, vol.324
, pp. 654-657
-
-
Nakahata, Y.1
Sahar, S.2
Astarita, G.3
Kaluzova, M.4
Sassone-Corsi, P.5
-
109
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D.M., Kwong L.K., Truax A.C., Micsenyi M.C., Chou T.T., Bruce J., Schuck T., Grossman M., Clark C.M., et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006, 314:130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
-
110
-
-
84876789195
-
Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets
-
Nimmagadda V.K., Bever C.T., Vattikunta N.R., Talat S., Ahmad V., Nagalla N.K., Trisler D., Judge S.I., Royal W., Chandrasekaran K., et al. Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets. J.Immunol. 2013, 190:4595-4607.
-
(2013)
J.Immunol.
, vol.190
, pp. 4595-4607
-
-
Nimmagadda, V.K.1
Bever, C.T.2
Vattikunta, N.R.3
Talat, S.4
Ahmad, V.5
Nagalla, N.K.6
Trisler, D.7
Judge, S.I.8
Royal, W.9
Chandrasekaran, K.10
-
111
-
-
84878413968
-
Expression of SIRT1 and cortactin is associated with progression of non-small cell lung cancer
-
Noh S.J., Baek H.A., Park H.S., Jang K.Y., Moon W.S., Kang M.J., Lee D.G., Kim M.H., Lee J.H., Chung M.J. Expression of SIRT1 and cortactin is associated with progression of non-small cell lung cancer. Pathol. Res. Pract. 2013, 209:365-370.
-
(2013)
Pathol. Res. Pract.
, vol.209
, pp. 365-370
-
-
Noh, S.J.1
Baek, H.A.2
Park, H.S.3
Jang, K.Y.4
Moon, W.S.5
Kang, M.J.6
Lee, D.G.7
Kim, M.H.8
Lee, J.H.9
Chung, M.J.10
-
112
-
-
2942564591
-
Sirtuins: Sir2-related NAD-dependent protein deacetylases
-
North B.J., Verdin E. Sirtuins: Sir2-related NAD-dependent protein deacetylases. Genome Biol. 2004, 5:224.
-
(2004)
Genome Biol.
, vol.5
, pp. 224
-
-
North, B.J.1
Verdin, E.2
-
113
-
-
39149122568
-
Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis
-
North B.J., Verdin E. Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis. PloS One 2007, 2:e784.
-
(2007)
PloS One
, vol.2
-
-
North, B.J.1
Verdin, E.2
-
114
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North B.J., Marshall B.L., Borra M.T., Denu J.M., Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell 2003, 11:437-444.
-
(2003)
Mol. Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
115
-
-
0001158889
-
Experimental disseminated encephalomyelitis in white mice
-
Olitsky P.K., Yager R.H. Experimental disseminated encephalomyelitis in white mice. J.Exp. Med. 1949, 90:213-224.
-
(1949)
J.Exp. Med.
, vol.90
, pp. 213-224
-
-
Olitsky, P.K.1
Yager, R.H.2
-
116
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
Onyango P., Celic I., McCaffery J.M., Boeke J.D., Feinberg A.P. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc. Natl. Acad. Sci. USA 2002, 99:13653-13658.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
117
-
-
34547599329
-
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
-
Outeiro T.F., Kontopoulos E., Altmann S.M., Kufareva I., Strathearn K.E., Amore A.M., Volk C.B., Maxwell M.M., Rochet J.C., McLean P.J., et al. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science 2007, 317:516-519.
-
(2007)
Science
, vol.317
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
Volk, C.B.7
Maxwell, M.M.8
Rochet, J.C.9
McLean, P.J.10
-
118
-
-
53249114029
-
Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease
-
Pallos J., Bodai L., Lukacsovich T., Purcell J.M., Steffan J.S., Thompson L.M., Marsh J.L. Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. Hum. Mol. Genet. 2008, 17:3767-3775.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 3767-3775
-
-
Pallos, J.1
Bodai, L.2
Lukacsovich, T.3
Purcell, J.M.4
Steffan, J.S.5
Thompson, L.M.6
Marsh, J.L.7
-
119
-
-
84863011114
-
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
-
Park S.J., Ahmad F., Philp A., Baar K., Williams T., Luo H., Ke H., Rehmann H., Taussig R., Brown A.L., et al. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell 2012, 148:421-433.
-
(2012)
Cell
, vol.148
, pp. 421-433
-
-
Park, S.J.1
Ahmad, F.2
Philp, A.3
Baar, K.4
Williams, T.5
Luo, H.6
Ke, H.7
Rehmann, H.8
Taussig, R.9
Brown, A.L.10
-
120
-
-
16844375290
-
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
-
Parker J.A., Arango M., Abderrahmane S., Lambert E., Tourette C., Catoire H., Néri C. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat. Genet. 2005, 37:349-350.
-
(2005)
Nat. Genet.
, vol.37
, pp. 349-350
-
-
Parker, J.A.1
Arango, M.2
Abderrahmane, S.3
Lambert, E.4
Tourette, C.5
Catoire, H.6
Néri, C.7
-
121
-
-
84865704833
-
Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity
-
Parker J.A., Vazquez-Manrique R.P., Tourette C., Farina F., Offner N., Mukhopadhyay A., Orfila A.M., Darbois A., Menet S., Tissenbaum H.A., Neri C. Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity. J.Neurosci. 2012, 32:12630-12640.
-
(2012)
J.Neurosci.
, vol.32
, pp. 12630-12640
-
-
Parker, J.A.1
Vazquez-Manrique, R.P.2
Tourette, C.3
Farina, F.4
Offner, N.5
Mukhopadhyay, A.6
Orfila, A.M.7
Darbois, A.8
Menet, S.9
Tissenbaum, H.A.10
Neri, C.11
-
122
-
-
84884248040
-
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice
-
Peek C.B., Affinati A.H., Ramsey K.M., Kuo H.Y., Yu W., Sena L.A., Ilkayeva O., Marcheva B., Kobayashi Y., Omura C., et al. Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science 2013, 342:1243417.
-
(2013)
Science
, vol.342
, pp. 1243417
-
-
Peek, C.B.1
Affinati, A.H.2
Ramsey, K.M.3
Kuo, H.Y.4
Yu, W.5
Sena, L.A.6
Ilkayeva, O.7
Marcheva, B.8
Kobayashi, Y.9
Omura, C.10
-
123
-
-
83055173304
-
The first identification of lysine malonylation substrates and its regulatory enzyme
-
Peng C., Lu Z., Xie Z., Cheng Z., Chen Y., Tan M., Luo H., Zhang Y., He W., Yang K., et al. The first identification of lysine malonylation substrates and its regulatory enzyme. Mol. Cell. Proteomics 2011, 10:012658.
-
(2011)
Mol. Cell. Proteomics
, vol.10
, pp. 012658
-
-
Peng, C.1
Lu, Z.2
Xie, Z.3
Cheng, Z.4
Chen, Y.5
Tan, M.6
Luo, H.7
Zhang, Y.8
He, W.9
Yang, K.10
-
124
-
-
42349085704
-
Sirt1 contributes critically to the redox-dependent fate of neural progenitors
-
Prozorovski T., Schulze-Topphoff U., Glumm R., Baumgart J., Schröter F., Ninnemann O., Siegert E., Bendix I., Brüstle O., Nitsch R., et al. Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat. Cell Biol. 2008, 10:385-394.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 385-394
-
-
Prozorovski, T.1
Schulze-Topphoff, U.2
Glumm, R.3
Baumgart, J.4
Schröter, F.5
Ninnemann, O.6
Siegert, E.7
Bendix, I.8
Brüstle, O.9
Nitsch, R.10
-
126
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
-
Qin W., Yang T., Ho L., Zhao Z., Wang J., Chen L., Zhao W., Thiyagarajan M., MacGrogan D., Rodgers J.T., et al. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J.Biol. Chem. 2006, 281:21745-21754.
-
(2006)
J.Biol. Chem.
, vol.281
, pp. 21745-21754
-
-
Qin, W.1
Yang, T.2
Ho, L.3
Zhao, Z.4
Wang, J.5
Chen, L.6
Zhao, W.7
Thiyagarajan, M.8
MacGrogan, D.9
Rodgers, J.T.10
-
127
-
-
84878584955
-
Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain
-
Rafalski V.A., Ho P.P., Brett J.O., Ucar D., Dugas J.C., Pollina E.A., Chow L.M., Ibrahim A., Baker S.J., Barres B.A., et al. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat. Cell Biol. 2013, 15:614-624.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 614-624
-
-
Rafalski, V.A.1
Ho, P.P.2
Brett, J.O.3
Ucar, D.4
Dugas, J.C.5
Pollina, E.A.6
Chow, L.M.7
Ibrahim, A.8
Baker, S.J.9
Barres, B.A.10
-
128
-
-
54049158932
-
Brain SIRT1: anatomical distribution and regulation by energy availability
-
Ramadori G., Lee C.E., Bookout A.L., Lee S., Williams K.W., Anderson J., Elmquist J.K., Coppari R. Brain SIRT1: anatomical distribution and regulation by energy availability. J.Neurosci. 2008, 28:9989-9996.
-
(2008)
J.Neurosci.
, vol.28
, pp. 9989-9996
-
-
Ramadori, G.1
Lee, C.E.2
Bookout, A.L.3
Lee, S.4
Williams, K.W.5
Anderson, J.6
Elmquist, J.K.7
Coppari, R.8
-
129
-
-
77956644726
-
SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity
-
Ramadori G., Fujikawa T., Fukuda M., Anderson J., Morgan D.A., Mostoslavsky R., Stuart R.C., Perello M., Vianna C.R., Nillni E.A., et al. SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab. 2010, 12:78-87.
-
(2010)
Cell Metab.
, vol.12
, pp. 78-87
-
-
Ramadori, G.1
Fujikawa, T.2
Fukuda, M.3
Anderson, J.4
Morgan, D.A.5
Mostoslavsky, R.6
Stuart, R.C.7
Perello, M.8
Vianna, C.R.9
Nillni, E.A.10
-
130
-
-
80052700953
-
SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance
-
Ramadori G., Fujikawa T., Anderson J., Berglund E.D., Frazao R., Michán S., Vianna C.R., Sinclair D.A., Elias C.F., Coppari R. SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance. Cell Metab. 2011, 14:301-312.
-
(2011)
Cell Metab.
, vol.14
, pp. 301-312
-
-
Ramadori, G.1
Fujikawa, T.2
Anderson, J.3
Berglund, E.D.4
Frazao, R.5
Michán, S.6
Vianna, C.R.7
Sinclair, D.A.8
Elias, C.F.9
Coppari, R.10
-
131
-
-
38349112898
-
Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice
-
Ramsey K.M., Mills K.F., Satoh A., Imai S. Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice. Aging Cell 2008, 7:78-88.
-
(2008)
Aging Cell
, vol.7
, pp. 78-88
-
-
Ramsey, K.M.1
Mills, K.F.2
Satoh, A.3
Imai, S.4
-
132
-
-
84865246956
-
Heat shock and caloric restriction have a synergistic effect on the heat shock response in a sir2.1-dependent manner in Caenorhabditis elegans
-
Raynes R., Leckey B.D., Nguyen K., Westerheide S.D. Heat shock and caloric restriction have a synergistic effect on the heat shock response in a sir2.1-dependent manner in Caenorhabditis elegans. J.Biol. Chem. 2012, 287:29045-29053.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 29045-29053
-
-
Raynes, R.1
Leckey, B.D.2
Nguyen, K.3
Westerheide, S.D.4
-
133
-
-
65549142573
-
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins
-
Renthal W., Kumar A., Xiao G., Wilkinson M., Covington H.E., Maze I., Sikder D., Robison A.J., LaPlant Q., Dietz D.M., et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron 2009, 62:335-348.
-
(2009)
Neuron
, vol.62
, pp. 335-348
-
-
Renthal, W.1
Kumar, A.2
Xiao, G.3
Wilkinson, M.4
Covington, H.E.5
Maze, I.6
Sikder, D.7
Robison, A.J.8
LaPlant, Q.9
Dietz, D.M.10
-
134
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
ITALSGEN Consortium
-
Renton A.E., Majounie E., Waite A., Simón-Sánchez J., Rollinson S., Gibbs J.R., Schymick J.C., Laaksovirta H., van Swieten J.C., Myllykangas L., et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011, 72:257-268. ITALSGEN Consortium.
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
Simón-Sánchez, J.4
Rollinson, S.5
Gibbs, J.R.6
Schymick, J.C.7
Laaksovirta, H.8
van Swieten, J.C.9
Myllykangas, L.10
-
135
-
-
0018564390
-
A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci
-
Rine J., Strathern J.N., Hicks J.B., Herskowitz I. A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci. Genetics 1979, 93:877-901.
-
(1979)
Genetics
, vol.93
, pp. 877-901
-
-
Rine, J.1
Strathern, J.N.2
Hicks, J.B.3
Herskowitz, I.4
-
136
-
-
0021324896
-
DNA damage and chronic neuronal degenerations
-
Robison S.H., Bradley W.G. DNA damage and chronic neuronal degenerations. J.Neurol. Sci. 1984, 64:11-20.
-
(1984)
J.Neurol. Sci.
, vol.64
, pp. 11-20
-
-
Robison, S.H.1
Bradley, W.G.2
-
137
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J.P., Deng H.X., et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362:59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
138
-
-
84867280590
-
SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy
-
Sampaio-Marques B., Felgueiras C., Silva A., Rodrigues M., Tenreiro S., Franssens V., Reichert A.S., Outeiro T.F., Winderickx J., Ludovico P. SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy 2012, 8:1494-1509.
-
(2012)
Autophagy
, vol.8
, pp. 1494-1509
-
-
Sampaio-Marques, B.1
Felgueiras, C.2
Silva, A.3
Rodrigues, M.4
Tenreiro, S.5
Franssens, V.6
Reichert, A.S.7
Outeiro, T.F.8
Winderickx, J.9
Ludovico, P.10
-
139
-
-
77954470727
-
Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide
-
Sasaki T., Kim H.J., Kobayashi M., Kitamura Y.I., Yokota-Hashimoto H., Shiuchi T., Minokoshi Y., Kitamura T. Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide. Endocrinology 2010, 151:2556-2566.
-
(2010)
Endocrinology
, vol.151
, pp. 2556-2566
-
-
Sasaki, T.1
Kim, H.J.2
Kobayashi, M.3
Kitamura, Y.I.4
Yokota-Hashimoto, H.5
Shiuchi, T.6
Minokoshi, Y.7
Kitamura, T.8
-
140
-
-
77955344258
-
SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus
-
Satoh A., Brace C.S., Ben-Josef G., West T., Wozniak D.F., Holtzman D.M., Herzog E.D., Imai S. SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus. J.Neurosci. 2010, 30:10220-10232.
-
(2010)
J.Neurosci.
, vol.30
, pp. 10220-10232
-
-
Satoh, A.1
Brace, C.S.2
Ben-Josef, G.3
West, T.4
Wozniak, D.F.5
Holtzman, D.M.6
Herzog, E.D.7
Imai, S.8
-
141
-
-
84883476818
-
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
-
Satoh A., Brace C.S., Rensing N., Cliften P., Wozniak D.F., Herzog E.D., Yamada K.A., Imai S. Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab. 2013, 18:416-430.
-
(2013)
Cell Metab.
, vol.18
, pp. 416-430
-
-
Satoh, A.1
Brace, C.S.2
Rensing, N.3
Cliften, P.4
Wozniak, D.F.5
Herzog, E.D.6
Yamada, K.A.7
Imai, S.8
-
142
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
Schwer B., North B.J., Frye R.A., Ott M., Verdin E. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J.Cell Biol. 2002, 158:647-657.
-
(2002)
J.Cell Biol.
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
143
-
-
84859480382
-
SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death
-
Seo J.S., Moon M.H., Jeong J.K., Seol J.W., Lee Y.J., Park B.H., Park S.Y. SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death. Neurobiol. Aging 2012, 33:1110-1120.
-
(2012)
Neurobiol. Aging
, vol.33
, pp. 1110-1120
-
-
Seo, J.S.1
Moon, M.H.2
Jeong, J.K.3
Seol, J.W.4
Lee, Y.J.5
Park, B.H.6
Park, S.Y.7
-
144
-
-
34648837170
-
SIRT1 activation confers neuroprotection in experimental optic neuritis
-
Shindler K.S., Ventura E., Rex T.S., Elliott P., Rostami A. SIRT1 activation confers neuroprotection in experimental optic neuritis. Invest. Ophthalmol. Vis. Sci. 2007, 48:3602-3609.
-
(2007)
Invest. Ophthalmol. Vis. Sci.
, vol.48
, pp. 3602-3609
-
-
Shindler, K.S.1
Ventura, E.2
Rex, T.S.3
Elliott, P.4
Rostami, A.5
-
145
-
-
78650482951
-
Oral resveratrol reduces neuronal damage in a model of multiple sclerosis
-
Shindler K.S., Ventura E., Dutt M., Elliott P., Fitzgerald D.C., Rostami A. Oral resveratrol reduces neuronal damage in a model of multiple sclerosis. J.Neuroophthalmol. 2010, 30:328-339.
-
(2010)
J.Neuroophthalmol.
, vol.30
, pp. 328-339
-
-
Shindler, K.S.1
Ventura, E.2
Dutt, M.3
Elliott, P.4
Fitzgerald, D.C.5
Rostami, A.6
-
146
-
-
84876722719
-
Acute effects of resveratrol to enhance cocaine-induced dopamine neurotransmission in the striatum
-
Shuto T., Kuroiwa M., Koga Y., Kawahara Y., Sotogaku N., Toyomasu K., Nishi A. Acute effects of resveratrol to enhance cocaine-induced dopamine neurotransmission in the striatum. Neurosci. Lett. 2013, 542:107-112.
-
(2013)
Neurosci. Lett.
, vol.542
, pp. 107-112
-
-
Shuto, T.1
Kuroiwa, M.2
Koga, Y.3
Kawahara, Y.4
Sotogaku, N.5
Toyomasu, K.6
Nishi, A.7
-
147
-
-
36348975230
-
Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in Tcells involving activation of aryl hydrocarbon receptor and estrogen receptor
-
Singh N.P., Hegde V.L., Hofseth L.J., Nagarkatti M., Nagarkatti P. Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in Tcells involving activation of aryl hydrocarbon receptor and estrogen receptor. Mol. Pharmacol. 2007, 72:1508-1521.
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 1508-1521
-
-
Singh, N.P.1
Hegde, V.L.2
Hofseth, L.J.3
Nagarkatti, M.4
Nagarkatti, P.5
-
148
-
-
12944283150
-
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family
-
Smith J.S., Brachmann C.B., Celic I., Kenna M.A., Muhammad S., Starai V.J., Avalos J.L., Escalante-Semerena J.C., Grubmeyer C., Wolberger C., et al. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc. Natl. Acad. Sci. USA 2000, 97:6658-6663.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6658-6663
-
-
Smith, J.S.1
Brachmann, C.B.2
Celic, I.3
Kenna, M.A.4
Muhammad, S.5
Starai, V.J.6
Avalos, J.L.7
Escalante-Semerena, J.C.8
Grubmeyer, C.9
Wolberger, C.10
-
149
-
-
78651468722
-
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
Someya S., Yu W., Hallows W.C., Xu J., Vann J.M., Leeuwenburgh C., Tanokura M., Denu J.M., Prolla T.A. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 2010, 143:802-812.
-
(2010)
Cell
, vol.143
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
Xu, J.4
Vann, J.M.5
Leeuwenburgh, C.6
Tanokura, M.7
Denu, J.M.8
Prolla, T.A.9
-
151
-
-
77953724950
-
Protein deacetylase SIRT1 in the cytoplasm promotes nerve growthfactor-induced neurite outgrowth in PC12 cells
-
Sugino T., Maruyama M., Tanno M., Kuno A., Houkin K., Horio Y. Protein deacetylase SIRT1 in the cytoplasm promotes nerve growthfactor-induced neurite outgrowth in PC12 cells. FEBS Lett. 2010, 584:2821-2826.
-
(2010)
FEBS Lett.
, vol.584
, pp. 2821-2826
-
-
Sugino, T.1
Maruyama, M.2
Tanno, M.3
Kuno, A.4
Houkin, K.5
Horio, Y.6
-
152
-
-
0034795205
-
Oxidized lipoproteins, beta amyloid peptides and Alzheimer's disease
-
Sun A.Y., Draczynska-Lusiak B., Sun G.Y. Oxidized lipoproteins, beta amyloid peptides and Alzheimer's disease. Neurotox. Res. 2001, 3:167-178.
-
(2001)
Neurotox. Res.
, vol.3
, pp. 167-178
-
-
Sun, A.Y.1
Draczynska-Lusiak, B.2
Sun, G.Y.3
-
153
-
-
34250365395
-
Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1
-
Tanno M., Sakamoto J., Miura T., Shimamoto K., Horio Y. Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1. J.Biol. Chem. 2007, 282:6823-6832.
-
(2007)
J.Biol. Chem.
, vol.282
, pp. 6823-6832
-
-
Tanno, M.1
Sakamoto, J.2
Miura, T.3
Shimamoto, K.4
Horio, Y.5
-
154
-
-
0033598942
-
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
-
Tanny J.C., Dowd G.J., Huang J., Hilz H., Moazed D. An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell 1999, 99:735-745.
-
(1999)
Cell
, vol.99
, pp. 735-745
-
-
Tanny, J.C.1
Dowd, G.J.2
Huang, J.3
Hilz, H.4
Moazed, D.5
-
155
-
-
41449083867
-
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
-
Vakhrusheva O., Smolka C., Gajawada P., Kostin S., Boettger T., Kubin T., Braun T., Bober E. Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice. Circ. Res. 2008, 102:703-710.
-
(2008)
Circ. Res.
, vol.102
, pp. 703-710
-
-
Vakhrusheva, O.1
Smolka, C.2
Gajawada, P.3
Kostin, S.4
Boettger, T.5
Kubin, T.6
Braun, T.7
Bober, E.8
-
156
-
-
41949097891
-
C.elegans model identifies genetic modifiers ofalpha-synuclein inclusion formation during aging
-
van Ham T.J., Thijssen K.L., Breitling R., Hofstra R.M., Plasterk R.H., Nollen E.A. C.elegans model identifies genetic modifiers ofalpha-synuclein inclusion formation during aging. PLoS Genet. 2008, 4:e1000027.
-
(2008)
PLoS Genet.
, vol.4
-
-
van Ham, T.J.1
Thijssen, K.L.2
Breitling, R.3
Hofstra, R.M.4
Plasterk, R.H.5
Nollen, E.A.6
-
157
-
-
79953183390
-
The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin
-
Velásquez D.A., Martínez G., Romero A., Vázquez M.J., Boit K.D., Dopeso-Reyes I.G., López M., Vidal A., Nogueiras R., Diéguez C. The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin. Diabetes 2011, 60:1177-1185.
-
(2011)
Diabetes
, vol.60
, pp. 1177-1185
-
-
Velásquez, D.A.1
Martínez, G.2
Romero, A.3
Vázquez, M.J.4
Boit, K.D.5
Dopeso-Reyes, I.G.6
López, M.7
Vidal, A.8
Nogueiras, R.9
Diéguez, C.10
-
158
-
-
77950575506
-
AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism
-
Vingtdeux V., Giliberto L., Zhao H., Chandakkar P., Wu Q., Simon J.E., Janle E.M., Lobo J., Ferruzzi M.G., Davies P., Marambaud P. AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J.Biol. Chem. 2010, 285:9100-9113.
-
(2010)
J.Biol. Chem.
, vol.285
, pp. 9100-9113
-
-
Vingtdeux, V.1
Giliberto, L.2
Zhao, H.3
Chandakkar, P.4
Wu, Q.5
Simon, J.E.6
Janle, E.M.7
Lobo, J.8
Ferruzzi, M.G.9
Davies, P.10
Marambaud, P.11
-
159
-
-
80053223811
-
Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis
-
Wang J., Zhang Y., Tang L., Zhang N., Fan D. Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis. Neurosci. Lett. 2011, 503:250-255.
-
(2011)
Neurosci. Lett.
, vol.503
, pp. 250-255
-
-
Wang, J.1
Zhang, Y.2
Tang, L.3
Zhang, N.4
Fan, D.5
-
160
-
-
84875967350
-
Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer
-
Wauters E., Sanchez-Arevalo Lobo V.J., Pinho A.V., Mawson A., Herranz D., Wu J., Cowley M.J., Colvin E.K., Njicop E.N., Sutherland R.L., et al. Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer. Cancer Res. 2013, 73:2357-2367.
-
(2013)
Cancer Res.
, vol.73
, pp. 2357-2367
-
-
Wauters, E.1
Sanchez-Arevalo Lobo, V.J.2
Pinho, A.V.3
Mawson, A.4
Herranz, D.5
Wu, J.6
Cowley, M.J.7
Colvin, E.K.8
Njicop, E.N.9
Sutherland, R.L.10
-
161
-
-
60749101582
-
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
-
Westerheide S.D., Anckar J., Stevens S.M., Sistonen L., Morimoto R.I. Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 2009, 323:1063-1066.
-
(2009)
Science
, vol.323
, pp. 1063-1066
-
-
Westerheide, S.D.1
Anckar, J.2
Stevens, S.M.3
Sistonen, L.4
Morimoto, R.I.5
-
162
-
-
80052359850
-
Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease
-
Wu Y., Li X., Zhu J.X., Xie W., Le W., Fan Z., Jankovic J., Pan T. Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease. Neurosignals 2011, 19:163-174.
-
(2011)
Neurosignals
, vol.19
, pp. 163-174
-
-
Wu, Y.1
Li, X.2
Zhu, J.X.3
Xie, W.4
Le, W.5
Fan, Z.6
Jankovic, J.7
Pan, T.8
-
163
-
-
80055078948
-
CSF from amyotrophic lateral sclerosis patients produces glutamate independent death of rat motor brain cortical neurons: protection by resveratrol but not riluzole
-
Yáñez M., Galán L., Matías-Guiu J., Vela A., Guerrero A., García A.G. CSF from amyotrophic lateral sclerosis patients produces glutamate independent death of rat motor brain cortical neurons: protection by resveratrol but not riluzole. Brain Res. 2011, 1423:77-86.
-
(2011)
Brain Res.
, vol.1423
, pp. 77-86
-
-
Yáñez, M.1
Galán, L.2
Matías-Guiu, J.3
Vela, A.4
Guerrero, A.5
García, A.G.6
-
164
-
-
80053920774
-
Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice
-
Yoshino J., Mills K.F., Yoon M.J., Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011, 14:528-536.
-
(2011)
Cell Metab.
, vol.14
, pp. 528-536
-
-
Yoshino, J.1
Mills, K.F.2
Yoon, M.J.3
Imai, S.4
-
165
-
-
84878990866
-
Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway
-
Zhao Y.N., Li W.F., Li F., Zhang Z., Dai Y.D., Xu A.L., Qi C., Gao J.M., Gao J. Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway. Biochem. Biophys. Res. Commun. 2013, 435:597-602.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.435
, pp. 597-602
-
-
Zhao, Y.N.1
Li, W.F.2
Li, F.3
Zhang, Z.4
Dai, Y.D.5
Xu, A.L.6
Qi, C.7
Gao, J.M.8
Gao, J.9
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