Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence

Biochemical Pharmacology

Volumn 84, Issue 10, 2012, Pages 1332-1339

  Yao, Hongwei ^a   Rahman, Irfan ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Cellular senescence; DNA damage and repair; Inflammation; Senescence associated secretory phenotype; SIRT1; Telomere attrition

Indexed keywords

BETA CATENIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA 22; NOTCH RECEPTOR; PROTEIN P21; QUERCETIN; RESVERATROL; SIRTUIN 1; SULFORAPHANE; TRANSCRIPTION FACTOR FKHRL1; WERNER SYNDROME PROTEIN;

ACETYLATION; CELL AGING; CELL CYCLE ARREST; CHRONIC OBSTRUCTIVE LUNG DISEASE; DEACETYLATION; DISEASE COURSE; DNA DAMAGE; DNA REPAIR; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HISTONE ACETYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; HUMAN; INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SENESCENCE; TELOMERE; TRANSLATION INITIATION;

AGING, PREMATURE; ANIMALS; CELL AGING; DNA DAMAGE; HISTONES; HUMANS; INFLAMMATION; LUNG; OXIDATIVE STRESS; PNEUMONIA; POLYPHENOLS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIRTUIN 1; STEM CELLS; TELOMERE SHORTENING;

EID: 84867861519     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.06.031     Document Type: Review

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