PPARβ/δ regulates the human SIRT1 gene transcription via Sp1

Endocrine Journal

Volumn 57, Issue 5, 2010, Pages 403-413

  Okazaki, Mizuho ^a   Iwasaki, Yasumasa ^b   Nishiyama, Mitsuru ^a   Taguchi, Takafumi ^a   Tsugita, Makoto ^a   Nakayama, Shuichi ^a   Kambayashi, Machiko ^a   Hashimoto, Kozo ^c   Terada, Yoshio ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b KOCHI UNIVERSITY   (Japan)

^c Hosogi Unity Hospital   (Japan)

Author keywords

Longevity; PPAR ; SIRT1; Sirtuin; Sp1

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; CYCLIC AMP; GLUCAGON; GLUCOCORTICOID; INSULIN; MITHRAMYCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SIRTUIN 1; TRANSCRIPTION FACTOR SP1; HORMONE; SIRT1 PROTEIN, HUMAN; THIAZOLE DERIVATIVE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; GENE DELETION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; BIOLOGICAL MODEL; CELL CULTURE; DRUG EFFECT; DRUG POTENTIATION; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING;

BASE SEQUENCE; BINDING SITES; CELLS, CULTURED; GENE EXPRESSION REGULATION; HORMONES; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PPAR DELTA; PPAR-BETA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SIRTUIN 1; SP1 TRANSCRIPTION FACTOR; SUBSTRATE SPECIFICITY; THIAZOLES; TRANSCRIPTION, GENETIC;

EID: 77953633702     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K10E-004     Document Type: Article

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