Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart

Journal of Physiology

Volumn 592, Issue 12, 2014, Pages 2535-2548

  Sin, Thomas K ^a   Yu, Angus P ^a   Yung, Benjamin Y ^a   Yip, Shea Ping ^a   Chan, Lawrence W ^a   Wong, Cesar S ^a   Ying, Michael ^a   Rudd, John A ^b   Siu, Parco M ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b Chinese University of Hong Kong   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; BIM PROTEIN; PROTEIN BAX; PROTEIN P53; RESVERATROL; SIRTUIN 1; TRANSCRIPTION FACTOR FKHR; COLLAGEN; CYTOCHROME C OXIDASE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; SIRT1 PROTEIN, MOUSE; STILBENE DERIVATIVE;

ACETYLATION; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA FRAGMENTATION; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; HEART EJECTION FRACTION; HEART FUNCTION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSACTIVATION; TREATMENT DURATION; UPREGULATION; ANIMAL; DRUG EFFECTS; HEART; HEART LEFT VENTRICLE FUNCTION; HEART RATE; METABOLISM; PHYSIOLOGY;

ACETYLATION; AGING; ANIMALS; APOPTOSIS; COLLAGEN; ELECTRON TRANSPORT COMPLEX IV; FORKHEAD TRANSCRIPTION FACTORS; HEART; HEART RATE; MICE; SIGNAL TRANSDUCTION; SIRTUIN 1; STILBENES; VENTRICULAR FUNCTION, LEFT;

EID: 84902330009     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.271387     Document Type: Article

References (50)

1. Alamdari N, Aversa Z, Castillero E, Gurav A, Petkova V, Tizio S & Hasselgren PO (2012). Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism. Biochem Biophys Res Commun 417, 528-533.
2. Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF & Sadoshima J (2007). Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 100, 1512-1521.
3. Baar K, Wende AR, Jones TE, Marison M, Nolte LA, Chen M, Kelly DP & Holloszy JO (2002). Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J 16, 1879-1886.
4. Barger JL, Kayo T, Vann JM, Arias EB, Wang J, Hacker TA, Wang Y, Raederstorff D, Morrow JD, Leeuwenburgh C, Allison DB, Saupe KW, Cartee GD, Weindruch R & Prolla TA (2008). A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One 3, e2264.
5. Battiprolu PK, Hojayev B, Jiang N, Wang ZV, Luo X, Iglewski M, Shelton JM, Gerard RD, Rothermel BA, Gillette TG, Lavandero S & Hill JA (2012). Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice. J Clin Invest 122, 1109-1118.
6. Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS et al. (2006). Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342.
7. Biernacka A & Frangogiannis NG (2011). Aging and cardiac fibrosis. Aging Dis 2, 158-173.
8. Boyle AJ, Shih H, Hwang J, Ye J, Lee B, Zhang Y, Kwon D, Jun K, Zheng D, Sievers R, Angeli F, Yeghiazarians Y & Lee R (2011). Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Exp Gerontol 46, 549-559.
9. + metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS One 6, e19194.
10. Chan EC, Dusting GJ, Guo N, Peshavariya HM, Taylor CJ, Dilley R, Narumiya S & Jiang F (2010). Prostacyclin receptor suppresses cardiac fibrosis: role of CREB phosphorylation. J Mol Cell Cardiol 49, 176-185.
11. Chen CJ, Yu W, Fu YC, Wang X, Li JL & Wang W (2009). Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. Biochem Biophys Res Commun 378, 389-393.
12. Chen KH, Hung CC, Hsu HH, Jing YH, Yang CW & Chen JK (2011). Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats. Chem Biol Interact 190, 45-53.
13. Ferrara N, Rinaldi B, Corbi G, Conti V, Stiuso P, Boccuti S, Rengo G, Rossi F & Filippelli A (2008). Exercise training promotes SIRT1 activity in aged rats. Rejuvenation Res 11, 139-150.
14. Gazoti Debessa CR, Mesiano Maifrino LB & Rodrigues de Souza R (2001). Age related changes of the collagen network of the human heart. Mech Ageing Dev 122, 1049-1058.
15. Gu C, Xing Y, Jiang L, Chen M, Xu M, Yin Y, Li C, Yang Z, Yu L & Ma H (2013). Impaired cardiac SIRT1 activity by carbonyl stress contributes to aging-related ischemic intolerance. PLoS One 8, e74050.
16. Hancock CR, Han DH, Higashida K, Kim SH & Holloszy JO (2011). Does calorie restriction induce mitochondrial biogenesis? A reevaluation. FASEB J 25, 785-791.
17. Hariharan N, Maejima Y, Nakae J, Paik J, Depinho RA & Sadoshima J (2010). Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes. Circ Res 107, 1470-1482.
18. Higashida K, Kim SH, Jung SR, Asaka M, Holloszy JO & Han DH (2013). Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation. PLoS Biol 11, e1001603.
19. Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B & Sinclair DA (2003). Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425, 191-196.
20. Hsu CP, Zhai P, Yamamoto T, Maejima Y, Matsushima S, Hariharan N, Shao D, Takagi H, Oka S & Sadoshima J (2010). Silent information regulator 1 protects the heart from ischemia/reperfusion. Circulation 122, 2170-2182.
21. Hu YX, Cui H, Fan L, Pan XJ, Wu JH, Shi SZ, Cui SY, Wei ZM & Liu L (2013). Resveratrol attenuates left ventricular remodeling in old rats with COPD induced by cigarette smoke exposure and LPS instillation. Can J Physiol Pharmacol 91, 1044-1054.
22. Huang JP, Huang SS, Deng JY, Chang CC, Day YJ & Hung LM (2010). Insulin and resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the advantage of resveratrol in diabetics with acute heart attack is antagonized by insulin. Free Radic Biol Med 49, 1710-1721.
23. Jackson JR, Ryan MJ & Alway SE (2011). Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice. J Gerontol A Biol Sci Med Sci 66, 751-764.
24. Jothi M, Mal M, Keller C & Mal AK (2013). Small molecule inhibition of PAX3-FOXO1 through AKT activation suppresses malignant phenotypes of alveolar rhabdomyosarcoma. Mol Cancer Ther 12, 2663-2674.
25. Kuno A, Hori YS, Hosoda R, Tanno M, Miura T, Shimamoto K & Horio Y (2013). Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein. J Biol Chem 288, 5963-5972.
26. Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P & Auwerx J (2006). Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 127, 1109-1122.
27. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, Picard MH, Roman MJ, Seward J, Shanewise J, Solomon S, Spencer KT, St John SM & Stewart W (2006). Recommendations for chamber quantification. Eur J Echocardiogr 7, 79-108.
28. Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, de Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ et al. (2011). Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci 66, 191-201.
29. Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M & Guarente L (2004). Mammalian SIRT1 represses forkhead transcription factors. Cell 116, 551-563.
30. Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E, Moncada S & Carruba MO (2005). Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310, 314-317.
31. Olson ER, Naugle JE, Zhang X, Bomser JA & Meszaros JG (2005). Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol. Am J Physiol Heart Circ Physiol 288, H1131-H1138.
32. Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK et al. (2008). Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 8, 157-168.
33. Philp A, Chen A, Lan D, Meyer GA, Murphy AN, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K & Schenk S (2011). Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise. J Biol Chem 286, 30561-30570.
34. Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA & Colucci WS (2012). The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation 125, 1757-1764.
35. Rimbaud S, Ruiz M, Piquereau J, Mateo P, Fortin D, Veksler V, Garnier A & Ventura-Clapier R (2011). Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure. PLoS One 6, e26391.
36. Seymour EM, Bennink MR, Watts SW & Bolling SF (2010). Whole grape intake impacts cardiac peroxisome proliferator-activated receptor and nuclear factor kappaB activity and cytokine expression in rats with diastolic dysfunction. Hypertension 55, 1179-1185.
37. Shen B, Gao L, Hsu YT, Bledsoe G, Hagiwara M, Chao L & Chao J (2010). Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling. Am J Physiol Heart Circ Physiol 299, H1419-H1427.
38. + channels in both young and aged hearts. J Mol Cell Cardiol 39, 285-296.
39. Shinmura K, Tamaki K & Bolli R (2008). Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1. Am J Physiol Heart Circ Physiol 295, H2348-H2355.
40. Sin TK, Pei XM, Teng BT, Tam EW, Yung BY & Siu PM (2013). Oxidative stress and DNA damage signalling in skeletal muscle in pressure-induced deep tissue injury. Pflugers Arch 465, 295-317.
41. Sulaiman M, Matta MJ, Sunderesan NR, Gupta MP, Periasamy M & Gupta M (2010). Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 298, H833-H843.
42. Tanno M, Kuno A, Yano T, Miura T, Hisahara S, Ishikawa S, Shimamoto K & Horio Y (2010). Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure. J Biol Chem 285, 8375-8382.
43. Thandapilly SJ, Wojciechowski P, Behbahani J, Louis XL, Yu L, Juric D, Kopilas MA, Anderson HD & Netticadan T (2010). Resveratrol prevents the development of pathological cardiac hypertrophy and contractile dysfunction in the SHR without lowering blood pressure. Am J Hypertens 23, 192-196.
44. Van Der Heide LP, Hoekman MF & Smidt MP (2004). The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem J 380, 297-309.
45. Vucevic D, Mladenovic D, Ninkovic M, Aleksic V, Stankovic MN, Stankovic M, Jorgacevic B, Vukicevic RJ & Radosavljevic T (2013). The effects of caloric restriction against ethanol-induced oxidative and nitrosative cardiotoxicity and plasma lipids in rats. Exp Biol Med (Maywood) 238, 1396-1405.
46. Wei L, Wang M, Qu X, Mah A, Xiong X, Harris AG, Phillips LK, Martinez OM & Krams SM (2012). Differential expression of microRNAs during allograft rejection. Am J Transplant 12, 1113-1123.
47. Yang Y, Duan W, Lin Y, Yi W, Liang Z, Yan J, Wang N, Deng C, Zhang S, Li Y, Chen W, Yu S, Yi D & Jin Z (2013). SIRT1 activation by curcumin pretreatment attenuates mitochondrial oxidative damage induced by myocardial ischemia reperfusion injury. Free Radic Biol Med 65, 667-679.
48. Yang Y, Zhao Y, Liao W, Yang J, Wu L, Zheng Z, Yu Y, Zhou W, Li L, Feng J, Wang H & Zhu WG (2009). Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. Neoplasia 11, 313-324.
49. Zhang C, Feng Y, Qu S, Wei X, Zhu H, Luo Q, Liu M, Chen G & Xiao X (2011). Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53. Cardiovasc Res 90, 538-545.
50. Zhu W, Bijur GN, Styles NA & Li X (2004). Regulation of FOXO3a by brain-derived neurotrophic factor in differentiated human SH-SY5Y neuroblastoma cells. Brain Res Mol Brain Res 126, 45-56.