miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

FASEB Journal

Volumn 24, Issue 9, 2010, Pages 3255-3263

  Tarantino, Carolina ^a,b   Paolella, Gaetana ^a,c   Cozzuto, Luca ^a   Minopoli, Giuseppina ^a,c   Pastore, Lucio ^a,c   Parisi, Silvia ^a,b   Russo, Tommaso ^a,c  

^a CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^b Scuola Europea di Medicina Molecolare SEMM   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Jarid1b; Pluripotency; Sirt1; Smarca5

Indexed keywords

MESSENGER RNA; MICRORNA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYONIC STEM CELL; GENE; GENE EXPRESSION; GENE REPRESSION; JARID1B GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; SIRT1 GENE; SMARCA5 GENE;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; EMBRYONIC STEM CELLS; HUMANS; MICE; MICRORNAS; POLYMERASE CHAIN REACTION; TRANSFECTION;

EID: 77956640572     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-152207     Document Type: Article

References (44)

1. Bartel, D. P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297
2. Pillai, R. S. (2005) MicroRNA function: multiple mechanisms for a tiny RNA? RNA 11, 1753-1761
3. Kato, M., Slack, F. J. (2008) microRNAs: small molecules with big roles - C. elegans to human cancer. Biol. Cell 100, 71-81 (Pubitemid 351266765)
4. Niwa, H. (2007) How is pluripotency determined and maintained? Development 134, 635-646
5. Kanellopoulou, C., Muljo, S. A., Kung, A. L., Ganesan, S., Drapkin, R., Jenuwein, T., Livingston, D. M., and Rajewsky, K. (2005) Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19, 489-501 (Pubitemid 40256280)
6. Murchison, E. P., Partridge, J. F., Tam, O. H., Cheloufi, S., and Hannon, G. J. (2005) Characterization of Dicer-deficient murine embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A. 102, 12135-12140 (Pubitemid 41291141)
7. Wang, Y., Medvid, R., Melton, C., Jaenisch, R., and Blelloch, R. (2007) DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Genet. 39, 380-385 (Pubitemid 46328490)
8. Houbaviy, H. B., Murray, M. F., Sharp, P. A. (2003) Embryonic stem cell-specific microRNAs. Dev. Cell. 5, 351-358
9. Wang, Y., Baskerville, S., Shenoy, A., Babiarz, J. E., Baehner, L., Blelloch, R. (2008) Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat. Genet. 40, 1478-1483
10. Sinkkonen, L., Hugenschmidt, T., Berninger, P., Gaidatzis, D., Mohn, F., Artus-Revel, C. G., Zavolan, M., Svoboda, P., and Filipowicz, W. (2008) MicroRNAs control de novo methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat. Struct. Mol. Biol. 15, 259-267 (Pubitemid 351654045)
11. Tay, Y., Zhang, J., Thomson, A. M., Lim, B., Rigoutsos, I. (2008) MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 455, 1124-1128
12. Lin, C. H., Jackson, A. L., Guo, J., Linsley, P. S., Eisenman, R. N. (2009) Myc-regulated microRNAs attenuate embryonic stem cell differentiation. EMBO J. 28, 3157-3170
13. Parisi, S., Passaro, F., Aloia, L., Manabe, I., Nagai, R., Pastore, L., and Russo, T. (2008) Klf5 is involved in self-renewal of mouse embryonic stem cells. J. Cell Sci. 121, 2629-2634
14. Nagy, A; Rossant, J; Nagy, R; Abramow-Newerly, W; Roder, J. C. (1993) Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A. 90, 8424-8428
15. Dressel, R., Schindehütte, J., Kuhlmann, T., Elsner, L., Novota, P., Baier, P. C., Schillert, A., Bickeböller, H., Herrmann, T., Trenkwalder, C., Paulus, W., Mansouri, A. (2008) The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response (Online). PLoS One 3, e2622
16. Loh, Y-H., Wu, Q., Chew, J. L., Vega, V. B., Zhang, W., Chen, X., Bourque, G., George, J., Leong, B., Liu, J., Wong, K. Y., Sung, K. W., Lee, C. W., Zhao, X. D., Chiu, K. P., Lipovich, L., Kuznetsov, V. A., Robson, P., Stanton, L. W., Wei, C. L., Ruan, Y., Lim, B., and Ng, H. H. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat. Genet. 38, 431-440
17. Visvanathan, J., Lee, S., Lee, B., Lee, J. W., Lee, S. K. (2007) The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749 (Pubitemid 46572354)
18. Ziegelbauer, J. M., Sullivan, C. S., and Ganem, D. (2009) Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAs. Nat. Genet. 41, 130-134
19. Li, X., and Zhao, X. (2008) Epigenetic regulation of mammalian stem cells. Stem Cells Dev. 17, 1043-1052
20. LeRoy, G., Loyola, A., Lane, W. S., and Reinberg, D. (2000) Purification and characterization of a human factor that assembles and remodels chromatin. J. Biol. Chem. 275, 14787-14790
21. Stopka, T., and Skoultchi, A. I. (2003) The ISWI ATPase Snf2h is required for early mouse development. Proc. Natl. Acad. Sci. U. S. A. 100, 14097-14102
22. Seward, D. J., Cubberley, G., Kim, S., Schonewald, M., Zhang, L., Tripet, B., and Bentley, D. L. (2007) Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins. Nat. Struct. Mol. Biol. 14, 240-242
23. Dey, B. K., Stalker, L., Schnerch, A., Bhatia, M., Taylor-Papidimitriou, J., and Wynder, C. (2008) The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation. Mol. Cell. Biol. 28, 5312-5327
24. Vaziri, H., Dessain, S. K., Ng, E. E., Imai, S. I., Frye, R. A., Pandita, T. K., Guarente, L., and Weinberg, R. A. (2001) hSIR2 (SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107, 149-159
25. Han, M. K., Song, E. K., Guo, Y., Ou, X., Mantel, C., and Broxmeyer, H. E. (2008) SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2, 241-251
26. Yamakuchi, M., Ferlito, M., and Lowenstein, C. J. (2008) miR- 34a repression of SIRT1 regulates apoptosis. Proc. Natl. Acad. Sci. U. S. A. 105, 13421-13426
27. Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Schöler, H., and Smith, A. (1998) Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391 (Pubitemid 28507326)
28. Mitsui, K., Tokuzawa, Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K., Maruyama, M., Maeda, M., and Yamanaka, S. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113, 631-642 (Pubitemid 36694188)
29. Rogers, M. B., Hosler, B. A., and Gudas, L. J. (1991) Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes. Development 113, 815-824
30. Krichevsky, A. M., Sonntag, K. C., Isacson, O., and Kosik, K. S. (2006) Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24, 857-864 (Pubitemid 44464719)
31. Calabrese, J. M., Seila, A. C., Yeo, G. W., and Sharp, P. A. (2007) RNA sequence analysis defines Dicer's role in mouse embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A. 104, 18097-18102
32. Ciaudo C., Servant, N., Cognat, V., Sarazin, A., Kieffer, E., Viville, S., Colot, V., Barillot, E., Heard, E., and Voinnet, O. (2009) Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation (Online). PLoS Genet 5, e1000620
33. Iorio, M. V., Visone, R., Di Leva, G., Donati, V., Petrocca, F., Casalini, P., Taccioli, C., Volinia, S., Liu, C. G., Alder, H., Calin, G. A., Ménard, S., and Croce, C. M. (2007) MicroRNA signatures in human ovarian cancer. Cancer Res. 67, 8699-8707
34. Yang, H., Kong, W., He, L., Zhao, J. J., O'Donnell, J. D., Wang, J., Wenham, R. M., Coppola, D., Kruk, P. A., Nicosia, S. V., and Cheng, J. Q. (2008) MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res. 68, 425-433
35. Henson, B. J., Bhattacharjee, S., O'Dee, D. M., Feingold, E., and Gollin, S. M. (2009) Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Genes Chromosomes Cancer 48, 569-582
36. Kozaki, K., Imoto, I., Mogi, S., Omura, K., and Inazawa, J. (2008) Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res. 68, 2094-2105 (Pubitemid 351521781)
37. Silber, J., Lim, D. A., Petritsch, C., Persson, A. I., Maunakea, A. K., Yu, M., Vandenberg, S. R., Ginzinger, D. G., James, C. D., Costello, J. F., Bergers, G., Weiss, W. A., Alvarez-Buylla, A., and Hodgson, J. G. (2008) miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med. 24, 6-14
38. Chang, T. C., Wentzel, E. A., Kent, O. A., Ramachandran, K., Mullendore, M., Lee, K. H., Feldmann, G., Yamakuchi, M., Ferlito, M., Lowenstein, C. J., Arking, D. E., Beer, M. A., Maitra, A., and Mendell, J. T. (2007) Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell. 26, 745-752
39. He, He, L., X., Lim, L. P., de Stanchina, E., Xuan, Z., Liang, Y., Xue, W., Zender, L., Magnus, J., Ridzon, D., Jackson, A. L., Linsley, P. S., Chen, C., Lowe, S. W., Cleary, M. A., and Hannon, G. J. (2007) A microRNA component of the p53 tumour suppressor network. Nature 447, 1130-1134
40. Hermeking, H. (2010) The miR-34 family in cancer and apoptosis. Cell Death Differ. 17, 193-199
41. Lin, T., Chao, C., Saito, S., Mazur, S. J., Murphy, M. E., Appella, E., and Xu, Y. (2005) p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat. Cell Biol. 7, 165-171 (Pubitemid 40268131)
42. Hashimi, S. T., Fulcher, J. A., Chang, M. H., Gov, L., Wang, S., and Lee, B. (2009) MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. Blood 114, 404-414
43. Miyabayashi, T., Teo, J. L., Yamamoto, M., McMillan, M., Nguyen, C., and Kahn, M. (2007) Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency, Proc. Natl. Acad. Sci. U. S. A. 104, 5668-5673 (Pubitemid 47175738)
44. Sampath, P., Pritchard, D. K., Pabon, L., Reinecke, H., Schwartz, S. M., Morris, D. R., and Murry, C. E. (2008) A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation. Cell Stem Cell 2, 448-460