-
1
-
-
72149125838
-
The transcellular spread of cytosolic amyloids, prions, and prionoids
-
Aguzzi A., Rajendran L. The transcellular spread of cytosolic amyloids, prions, and prionoids. Neuron 2009, 64:783-790.
-
(2009)
Neuron
, vol.64
, pp. 783-790
-
-
Aguzzi, A.1
Rajendran, L.2
-
2
-
-
84899944338
-
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
-
Ahmed Z., Cooper J., Murray T.K., Garn K., McNaughton E., Clarke H., Parhizkar S., Ward M.A., Cavallini A., Jackson S., et al. A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity. Acta Neuropathol. 2014, 127:667-683.
-
(2014)
Acta Neuropathol.
, vol.127
, pp. 667-683
-
-
Ahmed, Z.1
Cooper, J.2
Murray, T.K.3
Garn, K.4
McNaughton, E.5
Clarke, H.6
Parhizkar, S.7
Ward, M.A.8
Cavallini, A.9
Jackson, S.10
-
3
-
-
84893508018
-
Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations
-
Alami N.H., Smith R.B., Carrasco M.A., Williams L.A., Winborn C.S., Han S.S.W., Kiskinis E., Winborn B., Freibaum B.D., Kanagaraj A., et al. Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations. Neuron 2014, 81:536-543.
-
(2014)
Neuron
, vol.81
, pp. 536-543
-
-
Alami, N.H.1
Smith, R.B.2
Carrasco, M.A.3
Williams, L.A.4
Winborn, C.S.5
Han, S.S.W.6
Kiskinis, E.7
Winborn, B.8
Freibaum, B.D.9
Kanagaraj, A.10
-
4
-
-
63049091236
-
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins
-
Alberti S., Halfmann R., King O., Kapila A., Lindquist S. A systematic survey identifies prions and illuminates sequence features of prionogenic proteins. Cell 2009, 137:146-158.
-
(2009)
Cell
, vol.137
, pp. 146-158
-
-
Alberti, S.1
Halfmann, R.2
King, O.3
Kapila, A.4
Lindquist, S.5
-
5
-
-
48749090279
-
Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies
-
Alonso A.C., Li B., Grundke-Iqbal I., Iqbal K. Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies. Curr. Alzheimer Res. 2008, 5:375-384.
-
(2008)
Curr. Alzheimer Res.
, vol.5
, pp. 375-384
-
-
Alonso, A.C.1
Li, B.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
6
-
-
84886654903
-
Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases
-
Arnold S.E., Toledo J.B., Appleby D.H., Xie S.X., Wang L.-S., Baek Y., Wolk D.A., Lee E.B., Miller B.L., Lee V.M.-Y., Trojanowski J.Q. Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases. J. Comp. Neurol. 2013, 521:4339-4355.
-
(2013)
J. Comp. Neurol.
, vol.521
, pp. 4339-4355
-
-
Arnold, S.E.1
Toledo, J.B.2
Appleby, D.H.3
Xie, S.X.4
Wang, L.-S.5
Baek, Y.6
Wolk, D.A.7
Lee, E.B.8
Miller, B.L.9
Lee, V.M.-Y.10
Trojanowski, J.Q.11
-
7
-
-
84904646033
-
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
-
Baroja-Mazo A., Martín-Sánchez F., Gomez A.I., Martínez C.M., Amores-Iniesta J., Compan V., Barberà-Cremades M., Yagüe J., Ruiz-Ortiz E., Antón J., et al. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nat. Immunol. 2014, 15:738-748.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 738-748
-
-
Baroja-Mazo, A.1
Martín-Sánchez, F.2
Gomez, A.I.3
Martínez, C.M.4
Amores-Iniesta, J.5
Compan, V.6
Barberà-Cremades, M.7
Yagüe, J.8
Ruiz-Ortiz, E.9
Antón, J.10
-
8
-
-
84879047960
-
Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease
-
Basurto-Islas G., Grundke-Iqbal I., Tung Y.C., Liu F., Iqbal K. Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease. J. Biol. Chem. 2013, 288:17495-17507.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 17495-17507
-
-
Basurto-Islas, G.1
Grundke-Iqbal, I.2
Tung, Y.C.3
Liu, F.4
Iqbal, K.5
-
9
-
-
0023888782
-
Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da
-
Bellinger-Kawahara C.G., Kempner E., Groth D., Gabizon R., Prusiner S.B. Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da. Virology 1988, 164:537-541.
-
(1988)
Virology
, vol.164
, pp. 537-541
-
-
Bellinger-Kawahara, C.G.1
Kempner, E.2
Groth, D.3
Gabizon, R.4
Prusiner, S.B.5
-
10
-
-
0028043661
-
Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy
-
Bessen R.A., Marsh R.F. Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. J. Virol. 1994, 68:7859-7868.
-
(1994)
J. Virol.
, vol.68
, pp. 7859-7868
-
-
Bessen, R.A.1
Marsh, R.F.2
-
11
-
-
84878577036
-
α-Synuclein posttranslational modification and alternative splicing as a trigger for neurodegeneration
-
Beyer K., Ariza A. α-Synuclein posttranslational modification and alternative splicing as a trigger for neurodegeneration. Mol. Neurobiol. 2013, 47:509-524.
-
(2013)
Mol. Neurobiol.
, vol.47
, pp. 509-524
-
-
Beyer, K.1
Ariza, A.2
-
12
-
-
0020490156
-
Identification of a protein that purifies with the scrapie prion
-
Bolton D.C., McKinley M.P., Prusiner S.B. Identification of a protein that purifies with the scrapie prion. Science 1982, 218:1309-1311.
-
(1982)
Science
, vol.218
, pp. 1309-1311
-
-
Bolton, D.C.1
McKinley, M.P.2
Prusiner, S.B.3
-
13
-
-
84929709813
-
Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brains
-
Boluda S., Iba M., Zhang B., Raible K.M., Lee V.M.-Y., Trojanowski J.Q. Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brains. Acta Neuropathol. 2015, 129:221-237.
-
(2015)
Acta Neuropathol.
, vol.129
, pp. 221-237
-
-
Boluda, S.1
Iba, M.2
Zhang, B.3
Raible, K.M.4
Lee, V.M.-Y.5
Trojanowski, J.Q.6
-
14
-
-
84892150877
-
Structural and functional characterization of two alpha-synuclein strains
-
Bousset L., Pieri L., Ruiz-Arlandis G., Gath J., Jensen P.H., Habenstein B., Madiona K., Olieric V., Böckmann A., Meier B.H., Melki R. Structural and functional characterization of two alpha-synuclein strains. Nat. Commun. 2013, 4:2575.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2575
-
-
Bousset, L.1
Pieri, L.2
Ruiz-Arlandis, G.3
Gath, J.4
Jensen, P.H.5
Habenstein, B.6
Madiona, K.7
Olieric, V.8
Böckmann, A.9
Meier, B.H.10
Melki, R.11
-
15
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991, 82:239-259.
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
16
-
-
0029013727
-
Staging of Alzheimer's disease-related neurofibrillary changes
-
discussion 278-284
-
Braak H., Braak E. Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol. Aging 1995, 16:271-278. discussion 278-284.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 271-278
-
-
Braak, H.1
Braak, E.2
-
17
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H., Del Tredici K., Rüb U., de Vos R.A.I., Jansen Steur E.N.H., Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 2003, 24:197-211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rüb, U.3
de Vos, R.A.I.4
Jansen Steur, E.N.H.5
Braak, E.6
-
18
-
-
85019299311
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
Braak, H., Alafuzoff, I., Arzberger, T., Kretzschmar, H., and Del Tredici, K. (2006). Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry.
-
(2006)
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Del Tredici, K.5
-
19
-
-
84893364894
-
Phase transitions and size scaling of membrane-less organelles
-
Brangwynne C.P. Phase transitions and size scaling of membrane-less organelles. J. Cell Biol. 2013, 203:875-881.
-
(2013)
J. Cell Biol.
, vol.203
, pp. 875-881
-
-
Brangwynne, C.P.1
-
20
-
-
67649976463
-
Germline P granules are liquid droplets that localize by controlled dissolution/condensation
-
Brangwynne C.P., Eckmann C.R., Courson D.S., Rybarska A., Hoege C., Gharakhani J., Jülicher F., Hyman A.A. Germline P granules are liquid droplets that localize by controlled dissolution/condensation. Science 2009, 324:1729-1732.
-
(2009)
Science
, vol.324
, pp. 1729-1732
-
-
Brangwynne, C.P.1
Eckmann, C.R.2
Courson, D.S.3
Rybarska, A.4
Hoege, C.5
Gharakhani, J.6
Jülicher, F.7
Hyman, A.A.8
-
21
-
-
84883292041
-
Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
-
Brettschneider J., Del Tredici K., Toledo J.B., Robinson J.L., Irwin D.J., Grossman M., Suh E., Van Deerlin V.M., Wood E.M., Baek Y., et al. Stages of pTDP-43 pathology in amyotrophic lateral sclerosis. Ann. Neurol. 2013, 74:20-38.
-
(2013)
Ann. Neurol.
, vol.74
, pp. 20-38
-
-
Brettschneider, J.1
Del Tredici, K.2
Toledo, J.B.3
Robinson, J.L.4
Irwin, D.J.5
Grossman, M.6
Suh, E.7
Van Deerlin, V.M.8
Wood, E.M.9
Baek, Y.10
-
22
-
-
84926513913
-
Spreading of pathology in neurodegenerative diseases: a focus on human studies
-
Brettschneider J., Del Tredici K., Lee V.M.-Y., Trojanowski J.Q. Spreading of pathology in neurodegenerative diseases: a focus on human studies. Nat. Rev. Neurosci. 2015, 16:109-120.
-
(2015)
Nat. Rev. Neurosci.
, vol.16
, pp. 109-120
-
-
Brettschneider, J.1
Del Tredici, K.2
Lee, V.M.-Y.3
Trojanowski, J.Q.4
-
23
-
-
0027740178
-
Scrapie strain variation and mutation
-
Bruce M.E. Scrapie strain variation and mutation. Br. Med. Bull. 1993, 49:822-838.
-
(1993)
Br. Med. Bull.
, vol.49
, pp. 822-838
-
-
Bruce, M.E.1
-
24
-
-
84879349589
-
Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function
-
Buchan J.R., Kolaitis R.-M., Taylor J.P., Parker R. Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function. Cell 2013, 153:1461-1474.
-
(2013)
Cell
, vol.153
, pp. 1461-1474
-
-
Buchan, J.R.1
Kolaitis, R.-M.2
Taylor, J.P.3
Parker, R.4
-
25
-
-
84922942705
-
Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains
-
Bushman D.M., Kaeser G.E., Siddoway B., Westra J.W., Rivera R.R., Rehen S.K., Yung Y.C., Chun J. Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains. eLife 2015, 4:4.
-
(2015)
eLife
, vol.4
, pp. 4
-
-
Bushman, D.M.1
Kaeser, G.E.2
Siddoway, B.3
Westra, J.W.4
Rivera, R.R.5
Rehen, S.K.6
Yung, Y.C.7
Chun, J.8
-
26
-
-
84915752004
-
Prion-like polymerization as a signaling mechanism
-
Cai X., Chen Z.J. Prion-like polymerization as a signaling mechanism. Trends Immunol. 2014, 35:622-630.
-
(2014)
Trends Immunol.
, vol.35
, pp. 622-630
-
-
Cai, X.1
Chen, Z.J.2
-
27
-
-
84896381627
-
Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation
-
Cai X., Chen J., Xu H., Liu S., Jiang Q.-X., Halfmann R., Chen Z.J. Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation. Cell 2014, 156:1207-1222.
-
(2014)
Cell
, vol.156
, pp. 1207-1222
-
-
Cai, X.1
Chen, J.2
Xu, H.3
Liu, S.4
Jiang, Q.-X.5
Halfmann, R.6
Chen, Z.J.7
-
28
-
-
84864935106
-
Constitutive secretion of tau protein by an unconventional mechanism
-
Chai X., Dage J.L., Citron M. Constitutive secretion of tau protein by an unconventional mechanism. Neurobiol. Dis. 2012, 48:356-366.
-
(2012)
Neurobiol. Dis.
, vol.48
, pp. 356-366
-
-
Chai, X.1
Dage, J.L.2
Citron, M.3
-
29
-
-
0029052468
-
Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]
-
Chernoff Y.O., Lindquist S.L., Ono B., Inge-Vechtomov S.G., Liebman S.W. Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]. Science 1995, 268:880-884.
-
(1995)
Science
, vol.268
, pp. 880-884
-
-
Chernoff, Y.O.1
Lindquist, S.L.2
Ono, B.3
Inge-Vechtomov, S.G.4
Liebman, S.W.5
-
30
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera F., Bolmont T., Crowther R.A., Abramowski D., Frank S., Probst A., Fraser G., Stalder A.K., Beibel M., Staufenbiel M., et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat. Cell Biol. 2009, 11:909-913.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
-
31
-
-
84878723720
-
Brain homogenates from human tauopathies induce tau inclusions in mouse brain
-
Clavaguera F., Akatsu H., Fraser G., Crowther R.A., Frank S., Hench J., Probst A., Winkler D.T., Reichwald J., Staufenbiel M., et al. Brain homogenates from human tauopathies induce tau inclusions in mouse brain. Proc. Natl. Acad. Sci. USA 2013, 110:9535-9540.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 9535-9540
-
-
Clavaguera, F.1
Akatsu, H.2
Fraser, G.3
Crowther, R.A.4
Frank, S.5
Hench, J.6
Probst, A.7
Winkler, D.T.8
Reichwald, J.9
Staufenbiel, M.10
-
32
-
-
36049020231
-
A general model of prion strains and their pathogenicity
-
Collinge J., Clarke A.R. A general model of prion strains and their pathogenicity. Science 2007, 318:930-936.
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
33
-
-
0029831213
-
Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD
-
Collinge J., Sidle K.C., Meads J., Ironside J., Hill A.F. Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature 1996, 383:685-690.
-
(1996)
Nature
, vol.383
, pp. 685-690
-
-
Collinge, J.1
Sidle, K.C.2
Meads, J.3
Ironside, J.4
Hill, A.F.5
-
34
-
-
8844247180
-
Mechanism of prion propagation: amyloid growth occurs by monomer addition
-
Collins S.R., Douglass A., Vale R.D., Weissman J.S. Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLoS Biol. 2004, 2:e321.
-
(2004)
PLoS Biol.
, vol.2
, pp. e321
-
-
Collins, S.R.1
Douglass, A.2
Vale, R.D.3
Weissman, J.S.4
-
35
-
-
84883348572
-
Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes
-
Costanzo M., Abounit S., Marzo L., Danckaert A., Chamoun Z., Roux P., Zurzolo C. Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes. J. Cell Sci. 2013, 126:3678-3685.
-
(2013)
J. Cell Sci.
, vol.126
, pp. 3678-3685
-
-
Costanzo, M.1
Abounit, S.2
Marzo, L.3
Danckaert, A.4
Chamoun, Z.5
Roux, P.6
Zurzolo, C.7
-
36
-
-
0030885650
-
The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog
-
Coustou V., Deleu C., Saupe S., Begueret J. The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog. Proc. Natl. Acad. Sci. USA 1997, 94:9773-9778.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9773-9778
-
-
Coustou, V.1
Deleu, C.2
Saupe, S.3
Begueret, J.4
-
37
-
-
84862908655
-
A yeast functional screen predicts new candidate ALS disease genes
-
Couthouis J., Hart M.P., Shorter J., DeJesus-Hernandez M., Erion R., Oristano R., Liu A.X., Ramos D., Jethava N., Hosangadi D., et al. A yeast functional screen predicts new candidate ALS disease genes. Proc. Natl. Acad. Sci. USA 2011, 108:20881-20890.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 20881-20890
-
-
Couthouis, J.1
Hart, M.P.2
Shorter, J.3
DeJesus-Hernandez, M.4
Erion, R.5
Oristano, R.6
Liu, A.X.7
Ramos, D.8
Jethava, N.9
Hosangadi, D.10
-
38
-
-
84863507711
-
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
-
Couthouis J., Hart M.P., Erion R., King O.D., Diaz Z., Nakaya T., Ibrahim F., Kim H.-J., Mojsilovic-Petrovic J., Panossian S., et al. Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Hum. Mol. Genet. 2012, 21:2899-2911.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2899-2911
-
-
Couthouis, J.1
Hart, M.P.2
Erion, R.3
King, O.D.4
Diaz, Z.5
Nakaya, T.6
Ibrahim, F.7
Kim, H.-J.8
Mojsilovic-Petrovic, J.9
Panossian, S.10
-
39
-
-
84891741302
-
Chaperone-mediated autophagy: roles in disease and aging
-
Cuervo A.M., Wong E. Chaperone-mediated autophagy: roles in disease and aging. Cell Res. 2014, 24:92-104.
-
(2014)
Cell Res.
, vol.24
, pp. 92-104
-
-
Cuervo, A.M.1
Wong, E.2
-
40
-
-
79251565507
-
Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity
-
Danzer K.M., Ruf W.P., Putcha P., Joyner D., Hashimoto T., Glabe C., Hyman B.T., McLean P.J. Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. FASEB J. 2011, 25:326-336.
-
(2011)
FASEB J.
, vol.25
, pp. 326-336
-
-
Danzer, K.M.1
Ruf, W.P.2
Putcha, P.3
Joyner, D.4
Hashimoto, T.5
Glabe, C.6
Hyman, B.T.7
McLean, P.J.8
-
41
-
-
0141741347
-
Parkinson's disease: mechanisms and models
-
Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
42
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
de Calignon A., Polydoro M., Suárez-Calvet M., William C., Adamowicz D.H., Kopeikina K.J., Pitstick R., Sahara N., Ashe K.H., Carlson G.A., et al. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron 2012, 73:685-697.
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
de Calignon, A.1
Polydoro, M.2
Suárez-Calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
Pitstick, R.7
Sahara, N.8
Ashe, K.H.9
Carlson, G.A.10
-
43
-
-
34547491652
-
Formation of native prions from minimal components in vitro
-
Deleault N.R., Harris B.T., Rees J.R., Supattapone S. Formation of native prions from minimal components in vitro. Proc. Natl. Acad. Sci. USA 2007, 104:9741-9746.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 9741-9746
-
-
Deleault, N.R.1
Harris, B.T.2
Rees, J.R.3
Supattapone, S.4
-
44
-
-
0030482356
-
Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae
-
Derkatch I.L., Chernoff Y.O., Kushnirov V.V., Inge-Vechtomov S.G., Liebman S.W. Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae. Genetics 1996, 144:1375-1386.
-
(1996)
Genetics
, vol.144
, pp. 1375-1386
-
-
Derkatch, I.L.1
Chernoff, Y.O.2
Kushnirov, V.V.3
Inge-Vechtomov, S.G.4
Liebman, S.W.5
-
45
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
-
Desplats P., Lee H.-J., Bae E.-J., Patrick C., Rockenstein E., Crews L., Spencer B., Masliah E., Lee S.-J. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc. Natl. Acad. Sci. USA 2009, 106:13010-13015.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.-J.2
Bae, E.-J.3
Patrick, C.4
Rockenstein, E.5
Crews, L.6
Spencer, B.7
Masliah, E.8
Lee, S.-J.9
-
46
-
-
0014500760
-
A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7
-
Dickinson A.G., Meikle V.M. A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7. Genet. Res. 1969, 13:213-225.
-
(1969)
Genet. Res.
, vol.13
, pp. 213-225
-
-
Dickinson, A.G.1
Meikle, V.M.2
-
47
-
-
84903535019
-
Ectosomes: a new mechanism for non-exosomal secretion of tau protein
-
Dujardin S., Bégard S., Caillierez R., Lachaud C., Delattre L., Carrier S., Loyens A., Galas M.-C., Bousset L., Melki R., et al. Ectosomes: a new mechanism for non-exosomal secretion of tau protein. PLoS ONE 2014, 9:e100760.
-
(2014)
PLoS ONE
, vol.9
, pp. e100760
-
-
Dujardin, S.1
Bégard, S.2
Caillierez, R.3
Lachaud, C.4
Delattre, L.5
Carrier, S.6
Loyens, A.7
Galas, M.-C.8
Bousset, L.9
Melki, R.10
-
48
-
-
84903541550
-
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
-
Dujardin S., Lécolle K., Caillierez R., Bégard S., Zommer N., Lachaud C., Carrier S., Dufour N., Aurégan G., Winderickx J., et al. Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies. Acta Neuropathol. Commun. 2014, 2:14.
-
(2014)
Acta Neuropathol. Commun.
, vol.2
, pp. 14
-
-
Dujardin, S.1
Lécolle, K.2
Caillierez, R.3
Bégard, S.4
Zommer, N.5
Lachaud, C.6
Carrier, S.7
Dufour, N.8
Aurégan, G.9
Winderickx, J.10
-
49
-
-
84930960021
-
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
-
Elbaum-Garfinkle S., Kim Y., Szczepaniak K., Chen C.C.-H., Eckmann C.R., Myong S., Brangwynne C.P. The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics. Proc. Natl. Acad. Sci. USA 2015, 112:7189-7194.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 7189-7194
-
-
Elbaum-Garfinkle, S.1
Kim, Y.2
Szczepaniak, K.3
Chen, C.C.-H.4
Eckmann, C.R.5
Myong, S.6
Brangwynne, C.P.7
-
50
-
-
77952648551
-
Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival
-
Emmanouilidou E., Melachroinou K., Roumeliotis T., Garbis S.D., Ntzouni M., Margaritis L.H., Stefanis L., Vekrellis K. Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J. Neurosci. 2010, 30:6838-6851.
-
(2010)
J. Neurosci.
, vol.30
, pp. 6838-6851
-
-
Emmanouilidou, E.1
Melachroinou, K.2
Roumeliotis, T.3
Garbis, S.D.4
Ntzouni, M.5
Margaritis, L.H.6
Stefanis, L.7
Vekrellis, K.8
-
51
-
-
84920901644
-
Conformation determines the seeding potencies of native and recombinant Tau aggregates
-
Falcon B., Cavallini A., Angers R., Glover S., Murray T.K., Barnham L., Jackson S., O'Neill M.J., Isaacs A.M., Hutton M.L., et al. Conformation determines the seeding potencies of native and recombinant Tau aggregates. J. Biol. Chem. 2015, 290:1049-1065.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 1049-1065
-
-
Falcon, B.1
Cavallini, A.2
Angers, R.3
Glover, S.4
Murray, T.K.5
Barnham, L.6
Jackson, S.7
O'Neill, M.J.8
Isaacs, A.M.9
Hutton, M.L.10
-
52
-
-
3042788972
-
Cells release prions in association with exosomes
-
Fevrier B., Vilette D., Archer F., Loew D., Faigle W., Vidal M., Laude H., Raposo G. Cells release prions in association with exosomes. Proc. Natl. Acad. Sci. USA 2004, 101:9683-9688.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9683-9688
-
-
Fevrier, B.1
Vilette, D.2
Archer, F.3
Loew, D.4
Faigle, W.5
Vidal, M.6
Laude, H.7
Raposo, G.8
-
53
-
-
84931574130
-
The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3
-
Fioriti L., Myers C., Huang Y.-Y., Li X., Stephan J.S., Trifilieff P., Colnaghi L., Kosmidis S., Drisaldi B., Pavlopoulos E., Kandel E.R. The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3. Neuron 2015, 86:1433-1448.
-
(2015)
Neuron
, vol.86
, pp. 1433-1448
-
-
Fioriti, L.1
Myers, C.2
Huang, Y.-Y.3
Li, X.4
Stephan, J.S.5
Trifilieff, P.6
Colnaghi, L.7
Kosmidis, S.8
Drisaldi, B.9
Pavlopoulos, E.10
Kandel, E.R.11
-
54
-
-
84904692363
-
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
-
Franklin B.S., Bossaller L., De Nardo D., Ratter J.M., Stutz A., Engels G., Brenker C., Nordhoff M., Mirandola S.R., Al-Amoudi A., et al. The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nat. Immunol. 2014, 15:727-737.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 727-737
-
-
Franklin, B.S.1
Bossaller, L.2
De Nardo, D.3
Ratter, J.M.4
Stutz, A.5
Engels, G.6
Brenker, C.7
Nordhoff, M.8
Mirandola, S.R.9
Al-Amoudi, A.10
-
55
-
-
0015550206
-
Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation
-
Fraser H., Dickinson A.G. Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation. J. Comp. Pathol. 1973, 83:29-40.
-
(1973)
J. Comp. Pathol.
, vol.83
, pp. 29-40
-
-
Fraser, H.1
Dickinson, A.G.2
-
56
-
-
0021930726
-
Targeting of scrapie lesions and spread of agent via the retino-tectal projection
-
Fraser H., Dickinson A.G. Targeting of scrapie lesions and spread of agent via the retino-tectal projection. Brain Res. 1985, 346:32-41.
-
(1985)
Brain Res.
, vol.346
, pp. 32-41
-
-
Fraser, H.1
Dickinson, A.G.2
-
57
-
-
84947865675
-
On the identification of low allele frequency mosaic mutations in the brains of Alzheimer disease patients
-
Frigerio C.S., Lau P., Troakes C., Deramecourt V., Gele P., Van Loo P., Voet T., De Strooper B. On the identification of low allele frequency mosaic mutations in the brains of Alzheimer disease patients. Alzheimers Dement. 2015, 11:1265-1276.
-
(2015)
Alzheimers Dement.
, vol.11
, pp. 1265-1276
-
-
Frigerio, C.S.1
Lau, P.2
Troakes, C.3
Deramecourt, V.4
Gele, P.5
Van Loo, P.6
Voet, T.7
De Strooper, B.8
-
58
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost B., Jacks R.L., Diamond M.I. Propagation of tau misfolding from the outside to the inside of a cell. J. Biol. Chem. 2009, 284:12845-12852.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
59
-
-
63649160214
-
Conformational diversity of wild-type Tau fibrils specified by templated conformation change
-
Frost B., Ollesch J., Wille H., Diamond M.I. Conformational diversity of wild-type Tau fibrils specified by templated conformation change. J. Biol. Chem. 2009, 284:3546-3551.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 3546-3551
-
-
Frost, B.1
Ollesch, J.2
Wille, H.3
Diamond, M.I.4
-
60
-
-
0014021742
-
Experimental transmission of a Kuru-like syndrome to chimpanzees
-
Gajdusek D.C., Gibbs C.J., Alpers M. Experimental transmission of a Kuru-like syndrome to chimpanzees. Nature 1966, 209:794-796.
-
(1966)
Nature
, vol.209
, pp. 794-796
-
-
Gajdusek, D.C.1
Gibbs, C.J.2
Alpers, M.3
-
61
-
-
84940897433
-
Human Hsp70 Disaggregase Reverses Parkinson's-Linked α-Synuclein Amyloid Fibrils
-
Gao X., Carroni M., Nussbaum-Krammer C., Mogk A., Nillegoda N.B., Szlachcic A., Guilbride D.L., Saibil H.R., Mayer M.P., Bukau B. Human Hsp70 Disaggregase Reverses Parkinson's-Linked α-Synuclein Amyloid Fibrils. Mol. Cell 2015, 59:781-793.
-
(2015)
Mol. Cell
, vol.59
, pp. 781-793
-
-
Gao, X.1
Carroni, M.2
Nussbaum-Krammer, C.3
Mogk, A.4
Nillegoda, N.B.5
Szlachcic, A.6
Guilbride, D.L.7
Saibil, H.R.8
Mayer, M.P.9
Bukau, B.10
-
62
-
-
0032503968
-
Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins
-
Glover J.R., Lindquist S. Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins. Cell 1998, 94:73-82.
-
(1998)
Cell
, vol.94
, pp. 73-82
-
-
Glover, J.R.1
Lindquist, S.2
-
63
-
-
61849178720
-
Prions hijack tunnelling nanotubes for intercellular spread
-
Gousset K., Schiff E., Langevin C., Marijanovic Z., Caputo A., Browman D.T., Chenouard N., de Chaumont F., Martino A., Enninga J., et al. Prions hijack tunnelling nanotubes for intercellular spread. Nat. Cell Biol. 2009, 11:328-336.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 328-336
-
-
Gousset, K.1
Schiff, E.2
Langevin, C.3
Marijanovic, Z.4
Caputo, A.5
Browman, D.T.6
Chenouard, N.7
de Chaumont, F.8
Martino, A.9
Enninga, J.10
-
64
-
-
2942616602
-
Evidence for assembly of prions with left-handed beta-helices into trimers
-
Govaerts C., Wille H., Prusiner S.B., Cohen F.E. Evidence for assembly of prions with left-handed beta-helices into trimers. Proc. Natl. Acad. Sci. USA 2004, 101:8342-8347.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8342-8347
-
-
Govaerts, C.1
Wille, H.2
Prusiner, S.B.3
Cohen, F.E.4
-
65
-
-
57749172272
-
Resting-state functional connectivity reflects structural connectivity in the default mode network
-
Greicius M.D., Supekar K., Menon V., Dougherty R.F. Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb. Cortex 2009, 19:72-78.
-
(2009)
Cereb. Cortex
, vol.19
, pp. 72-78
-
-
Greicius, M.D.1
Supekar, K.2
Menon, V.3
Dougherty, R.F.4
-
66
-
-
84879895467
-
Distinct α-synuclein strains differentially promote tau inclusions in neurons
-
Guo J.L., Covell D.J., Daniels J.P., Iba M., Stieber A., Zhang B., Riddle D.M., Kwong L.K., Xu Y., Trojanowski J.Q., Lee V.M. Distinct α-synuclein strains differentially promote tau inclusions in neurons. Cell 2013, 154:103-117.
-
(2013)
Cell
, vol.154
, pp. 103-117
-
-
Guo, J.L.1
Covell, D.J.2
Daniels, J.P.3
Iba, M.4
Stieber, A.5
Zhang, B.6
Riddle, D.M.7
Kwong, L.K.8
Xu, Y.9
Trojanowski, J.Q.10
Lee, V.M.11
-
67
-
-
84857097463
-
Prions are a common mechanism for phenotypic inheritance in wild yeasts
-
Halfmann R., Jarosz D.F., Jones S.K., Chang A., Lancaster A.K., Lindquist S. Prions are a common mechanism for phenotypic inheritance in wild yeasts. Nature 2012, 482:363-368.
-
(2012)
Nature
, vol.482
, pp. 363-368
-
-
Halfmann, R.1
Jarosz, D.F.2
Jones, S.K.3
Chang, A.4
Lancaster, A.K.5
Lindquist, S.6
-
68
-
-
79960842310
-
Neuropathology underlying clinical variability in patients with synucleinopathies
-
Halliday G.M., Holton J.L., Revesz T., Dickson D.W. Neuropathology underlying clinical variability in patients with synucleinopathies. Acta Neuropathol. 2011, 122:187-204.
-
(2011)
Acta Neuropathol.
, vol.122
, pp. 187-204
-
-
Halliday, G.M.1
Holton, J.L.2
Revesz, T.3
Dickson, D.W.4
-
69
-
-
84860863700
-
Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies
-
Han T.W., Kato M., Xie S., Wu L.C., Mirzaei H., Pei J., Chen M., Xie Y., Allen J., Xiao G., McKnight S.L. Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies. Cell 2012, 149:768-779.
-
(2012)
Cell
, vol.149
, pp. 768-779
-
-
Han, T.W.1
Kato, M.2
Xie, S.3
Wu, L.C.4
Mirzaei, H.5
Pei, J.6
Chen, M.7
Xie, Y.8
Allen, J.9
Xiao, G.10
McKnight, S.L.11
-
70
-
-
84887031600
-
Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice
-
Heilbronner G., Eisele Y.S., Langer F., Kaeser S.A., Novotny R., Nagarathinam A., Aslund A., Hammarström P., Nilsson K.P.R., Jucker M. Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice. EMBO Rep. 2013, 14:1017-1022.
-
(2013)
EMBO Rep.
, vol.14
, pp. 1017-1022
-
-
Heilbronner, G.1
Eisele, Y.S.2
Langer, F.3
Kaeser, S.A.4
Novotny, R.5
Nagarathinam, A.6
Aslund, A.7
Hammarström, P.8
Nilsson, K.P.R.9
Jucker, M.10
-
71
-
-
0035910638
-
Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke
-
Hesse C., Rosengren L., Andreasen N., Davidsson P., Vanderstichele H., Vanmechelen E., Blennow K. Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke. Neurosci. Lett. 2001, 297:187-190.
-
(2001)
Neurosci. Lett.
, vol.297
, pp. 187-190
-
-
Hesse, C.1
Rosengren, L.2
Andreasen, N.3
Davidsson, P.4
Vanderstichele, H.5
Vanmechelen, E.6
Blennow, K.7
-
72
-
-
84870061595
-
Cellular mechanisms of protein aggregate propagation
-
Holmes B.B., Diamond M.I. Cellular mechanisms of protein aggregate propagation. Curr. Opin. Neurol. 2012, 25:721-726.
-
(2012)
Curr. Opin. Neurol.
, vol.25
, pp. 721-726
-
-
Holmes, B.B.1
Diamond, M.I.2
-
73
-
-
84882306577
-
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
-
Holmes B.B., DeVos S.L., Kfoury N., Li M., Jacks R., Yanamandra K., Ouidja M.O., Brodsky F.M., Marasa J., Bagchi D.P., et al. Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds. Proc. Natl. Acad. Sci. USA 2013, 110:E3138-E3147.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. E3138-E3147
-
-
Holmes, B.B.1
DeVos, S.L.2
Kfoury, N.3
Li, M.4
Jacks, R.5
Yanamandra, K.6
Ouidja, M.O.7
Brodsky, F.M.8
Marasa, J.9
Bagchi, D.P.10
-
74
-
-
84875740522
-
Heritable remodeling of yeast multicellularity by an environmentally responsive prion
-
Holmes D.L., Lancaster A.K., Lindquist S., Halfmann R. Heritable remodeling of yeast multicellularity by an environmentally responsive prion. Cell 2013, 153:153-165.
-
(2013)
Cell
, vol.153
, pp. 153-165
-
-
Holmes, D.L.1
Lancaster, A.K.2
Lindquist, S.3
Halfmann, R.4
-
75
-
-
84907894705
-
Proteopathic tau seeding predicts tauopathy in vivo
-
Holmes B.B., Furman J.L., Mahan T.E., Yamasaki T.R., Mirbaha H., Eades W.C., Belaygorod L., Cairns N.J., Holtzman D.M., Diamond M.I. Proteopathic tau seeding predicts tauopathy in vivo. Proc. Natl. Acad. Sci. USA 2014, 111:E4376-E4385.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. E4376-E4385
-
-
Holmes, B.B.1
Furman, J.L.2
Mahan, T.E.3
Yamasaki, T.R.4
Mirbaha, H.5
Eades, W.C.6
Belaygorod, L.7
Cairns, N.J.8
Holtzman, D.M.9
Diamond, M.I.10
-
76
-
-
19444376451
-
Heparan sulfate is a cellular receptor for purified infectious prions
-
Horonchik L., Tzaban S., Ben-Zaken O., Yedidia Y., Rouvinski A., Papy-Garcia D., Barritault D., Vlodavsky I., Taraboulos A. Heparan sulfate is a cellular receptor for purified infectious prions. J. Biol. Chem. 2005, 280:17062-17067.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17062-17067
-
-
Horonchik, L.1
Tzaban, S.2
Ben-Zaken, O.3
Yedidia, Y.4
Rouvinski, A.5
Papy-Garcia, D.6
Barritault, D.7
Vlodavsky, I.8
Taraboulos, A.9
-
77
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
Hou F., Sun L., Zheng H., Skaug B., Jiang Q.-X., Chen Z.J. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 2011, 146:448-461.
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.1
Sun, L.2
Zheng, H.3
Skaug, B.4
Jiang, Q.-X.5
Chen, Z.J.6
-
78
-
-
84886617003
-
Translation repressors, an RNA helicase, and developmental cues control RNP phase transitions during early development
-
Hubstenberger A., Noble S.L., Cameron C., Evans T.C. Translation repressors, an RNA helicase, and developmental cues control RNP phase transitions during early development. Dev. Cell 2013, 27:161-173.
-
(2013)
Dev. Cell
, vol.27
, pp. 161-173
-
-
Hubstenberger, A.1
Noble, S.L.2
Cameron, C.3
Evans, T.C.4
-
79
-
-
84959300842
-
Modifiers of solid RNP granules control normal RNP dynamics and mRNA activity in early development
-
Hubstenberger A., Cameron C., Noble S.L., Keenan S., Evans T.C. Modifiers of solid RNP granules control normal RNP dynamics and mRNA activity in early development. J. Cell Biol. 2015, 211:703-716.
-
(2015)
J. Cell Biol.
, vol.211
, pp. 703-716
-
-
Hubstenberger, A.1
Cameron, C.2
Noble, S.L.3
Keenan, S.4
Evans, T.C.5
-
81
-
-
84872346089
-
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
-
Iba M., Guo J.L., McBride J.D., Zhang B., Trojanowski J.Q., Lee V.M.-Y. Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy. J. Neurosci. 2013, 33:1024-1037.
-
(2013)
J. Neurosci.
, vol.33
, pp. 1024-1037
-
-
Iba, M.1
Guo, J.L.2
McBride, J.D.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
82
-
-
84939569230
-
Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections
-
Iba M., McBride J.D., Guo J.L., Zhang B., Trojanowski J.Q., Lee V.M.-Y. Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections. Acta Neuropathol. 2015, 130:349-362.
-
(2015)
Acta Neuropathol.
, vol.130
, pp. 349-362
-
-
Iba, M.1
McBride, J.D.2
Guo, J.L.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
83
-
-
78649941297
-
Exome sequencing reveals VCP mutations as a cause of familial ALS
-
Johnson J.O., Mandrioli J., Benatar M., Abramzon Y., Van Deerlin V.M., Trojanowski J.Q., Gibbs J.R., Brunetti M., Gronka S., Wuu J., et al. Exome sequencing reveals VCP mutations as a cause of familial ALS. Neuron 2010, 68:857-864. ITALSGEN Consortium.
-
(2010)
Neuron
, vol.68
, pp. 857-864
-
-
Johnson, J.O.1
Mandrioli, J.2
Benatar, M.3
Abramzon, Y.4
Van Deerlin, V.M.5
Trojanowski, J.Q.6
Gibbs, J.R.7
Brunetti, M.8
Gronka, S.9
Wuu, J.10
-
84
-
-
74049124412
-
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
-
Ju J.-S., Fuentealba R.A., Miller S.E., Jackson E., Piwnica-Worms D., Baloh R.H., Weihl C.C. Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease. J. Cell Biol. 2009, 187:875-888.
-
(2009)
J. Cell Biol.
, vol.187
, pp. 875-888
-
-
Ju, J.-S.1
Fuentealba, R.A.2
Miller, S.E.3
Jackson, E.4
Piwnica-Worms, D.5
Baloh, R.H.6
Weihl, C.C.7
-
85
-
-
84938131681
-
Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s
-
Kajava A.V., Klopffleisch K., Chen S., Hofmann K. Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s. Sci. Rep. 2014, 4:7436.
-
(2014)
Sci. Rep.
, vol.4
, pp. 7436
-
-
Kajava, A.V.1
Klopffleisch, K.2
Chen, S.3
Hofmann, K.4
-
86
-
-
79551565625
-
Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake
-
Kanekiyo T., Zhang J., Liu Q., Liu C.-C., Zhang L., Bu G. Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake. J. Neurosci. 2011, 31:1644-1651.
-
(2011)
J. Neurosci.
, vol.31
, pp. 1644-1651
-
-
Kanekiyo, T.1
Zhang, J.2
Liu, Q.3
Liu, C.-C.4
Zhang, L.5
Bu, G.6
-
87
-
-
84871141635
-
Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies
-
Karch C.M., Jeng A.T., Goate A.M. Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies. J. Biol. Chem. 2012, 287:42751-42762.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 42751-42762
-
-
Karch, C.M.1
Jeng, A.T.2
Goate, A.M.3
-
88
-
-
84860872161
-
Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels
-
Kato M., Han T.W., Xie S., Shi K., Du X., Wu L.C., Mirzaei H., Goldsmith E.J., Longgood J., Pei J., et al. Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell 2012, 149:753-767.
-
(2012)
Cell
, vol.149
, pp. 753-767
-
-
Kato, M.1
Han, T.W.2
Xie, S.3
Shi, K.4
Du, X.5
Wu, L.C.6
Mirzaei, H.7
Goldsmith, E.J.8
Longgood, J.9
Pei, J.10
-
89
-
-
84884587610
-
Stress granules and cell signaling: more than just a passing phase?
-
Kedersha N., Ivanov P., Anderson P. Stress granules and cell signaling: more than just a passing phase?. Trends Biochem. Sci. 2013, 38:494-506.
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 494-506
-
-
Kedersha, N.1
Ivanov, P.2
Anderson, P.3
-
90
-
-
77049123465
-
Interneuronal transfer of human tau between Lamprey central neurons in situ
-
Kim W., Lee S., Jung C., Ahmed A., Lee G., Hall G.F. Interneuronal transfer of human tau between Lamprey central neurons in situ. J. Alzheimers Dis. 2010, 19:647-664.
-
(2010)
J. Alzheimers Dis.
, vol.19
, pp. 647-664
-
-
Kim, W.1
Lee, S.2
Jung, C.3
Ahmed, A.4
Lee, G.5
Hall, G.F.6
-
91
-
-
84866183670
-
Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C)
-
Kim C., Haldiman T., Surewicz K., Cohen Y., Chen W., Blevins J., Sy M.-S., Cohen M., Kong Q., Telling G.C., et al. Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C). PLoS Pathog. 2012, 8:e1002835.
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1002835
-
-
Kim, C.1
Haldiman, T.2
Surewicz, K.3
Cohen, Y.4
Chen, W.5
Blevins, J.6
Sy, M.-S.7
Cohen, M.8
Kong, Q.9
Telling, G.C.10
-
92
-
-
84875898265
-
Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
-
Kim C., Ho D.-H., Suk J.-E., You S., Michael S., Kang J., Joong Lee S., Masliah E., Hwang D., Lee H.-J., Lee S.J. Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia. Nat. Commun. 2013, 4:1562.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1562
-
-
Kim, C.1
Ho, D.-H.2
Suk, J.-E.3
You, S.4
Michael, S.5
Kang, J.6
Joong Lee, S.7
Masliah, E.8
Hwang, D.9
Lee, H.-J.10
Lee, S.J.11
-
93
-
-
84875605133
-
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
-
Kim H.J., Kim N.C., Wang Y.-D., Scarborough E.A., Moore J., Diaz Z., MacLea K.S., Freibaum B., Li S., Molliex A., et al. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature 2013, 495:467-473.
-
(2013)
Nature
, vol.495
, pp. 467-473
-
-
Kim, H.J.1
Kim, N.C.2
Wang, Y.-D.3
Scarborough, E.A.4
Moore, J.5
Diaz, Z.6
MacLea, K.S.7
Freibaum, B.8
Li, S.9
Molliex, A.10
-
94
-
-
84862151933
-
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
-
King O.D., Gitler A.D., Shorter J. The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. Brain Res. 2012, 1462:61-80.
-
(2012)
Brain Res.
, vol.1462
, pp. 61-80
-
-
King, O.D.1
Gitler, A.D.2
Shorter, J.3
-
95
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
-
Kordower J.H., Chu Y., Hauser R.A., Freeman T.B., Olanow C.W. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat. Med. 2008, 14:504-506.
-
(2008)
Nat. Med.
, vol.14
, pp. 504-506
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Freeman, T.B.4
Olanow, C.W.5
-
96
-
-
84888440451
-
Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains
-
Kwon I., Kato M., Xiang S., Wu L., Theodoropoulos P., Mirzaei H., Han T., Xie S., Corden J.L., McKnight S.L. Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains. Cell 2013, 155:1049-1060.
-
(2013)
Cell
, vol.155
, pp. 1049-1060
-
-
Kwon, I.1
Kato, M.2
Xiang, S.3
Wu, L.4
Theodoropoulos, P.5
Mirzaei, H.6
Han, T.7
Xie, S.8
Corden, J.L.9
McKnight, S.L.10
-
97
-
-
84907221451
-
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
-
Kwon I., Xiang S., Kato M., Wu L., Theodoropoulos P., Wang T., Kim J., Yun J., Xie Y., McKnight S.L. Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells. Science 2014, 345:1139-1145.
-
(2014)
Science
, vol.345
, pp. 1139-1145
-
-
Kwon, I.1
Xiang, S.2
Kato, M.3
Wu, L.4
Theodoropoulos, P.5
Wang, T.6
Kim, J.7
Yun, J.8
Xie, Y.9
McKnight, S.L.10
-
99
-
-
0142227208
-
The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state
-
Lee S., Sowa M.E., Watanabe Y.-H., Sigler P.B., Chiu W., Yoshida M., Tsai F.T.F. The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell 2003, 115:229-240.
-
(2003)
Cell
, vol.115
, pp. 229-240
-
-
Lee, S.1
Sowa, M.E.2
Watanabe, Y.-H.3
Sigler, P.B.4
Chiu, W.5
Yoshida, M.6
Tsai, F.T.F.7
-
100
-
-
21344456506
-
Intravesicular localization and exocytosis of alpha-synuclein and its aggregates
-
Lee H.-J., Patel S., Lee S.-J. Intravesicular localization and exocytosis of alpha-synuclein and its aggregates. J. Neurosci. 2005, 25:6016-6024.
-
(2005)
J. Neurosci.
, vol.25
, pp. 6016-6024
-
-
Lee, H.-J.1
Patel, S.2
Lee, S.-J.3
-
101
-
-
79955660630
-
Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers
-
Lee H.-J., Baek S.M., Ho D.-H., Suk J.-E., Cho E.-D., Lee S.-J. Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers. Exp. Mol. Med. 2011, 43:216-222.
-
(2011)
Exp. Mol. Med.
, vol.43
, pp. 216-222
-
-
Lee, H.-J.1
Baek, S.M.2
Ho, D.-H.3
Suk, J.-E.4
Cho, E.-D.5
Lee, S.-J.6
-
102
-
-
84863011855
-
Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model
-
Lee S., Kim W., Li Z., Hall G.F. Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model. Int. J. Alzheimers Dis. 2012, 2012:172837.
-
(2012)
Int. J. Alzheimers Dis.
, vol.2012
, pp. 172837
-
-
Lee, S.1
Kim, W.2
Li, Z.3
Hall, G.F.4
-
103
-
-
34447639732
-
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes
-
Legname G., Nguyen H.-O.B., Peretz D., Cohen F.E., DeArmond S.J., Prusiner S.B. Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proc. Natl. Acad. Sci. USA 2006, 103:19105-19110.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19105-19110
-
-
Legname, G.1
Nguyen, H.-O.B.2
Peretz, D.3
Cohen, F.E.4
DeArmond, S.J.5
Prusiner, S.B.6
-
104
-
-
43249110200
-
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
-
Li J.-Y., Englund E., Holton J.L., Soulet D., Hagell P., Lees A.J., Lashley T., Quinn N.P., Rehncrona S., Björklund A., et al. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nat. Med. 2008, 14:501-503.
-
(2008)
Nat. Med.
, vol.14
, pp. 501-503
-
-
Li, J.-Y.1
Englund, E.2
Holton, J.L.3
Soulet, D.4
Hagell, P.5
Lees, A.J.6
Lashley, T.7
Quinn, N.P.8
Rehncrona, S.9
Björklund, A.10
-
105
-
-
84864240409
-
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
-
Li J., McQuade T., Siemer A.B., Napetschnig J., Moriwaki K., Hsiao Y.-S., Damko E., Moquin D., Walz T., McDermott A., et al. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 2012, 150:339-350.
-
(2012)
Cell
, vol.150
, pp. 339-350
-
-
Li, J.1
McQuade, T.2
Siemer, A.B.3
Napetschnig, J.4
Moriwaki, K.5
Hsiao, Y.-S.6
Damko, E.7
Moquin, D.8
Walz, T.9
McDermott, A.10
-
106
-
-
84878661360
-
Stress granules as crucibles of ALS pathogenesis
-
Li Y.R., King O.D., Shorter J., Gitler A.D. Stress granules as crucibles of ALS pathogenesis. J. Cell Biol. 2013, 201:361-372.
-
(2013)
J. Cell Biol.
, vol.201
, pp. 361-372
-
-
Li, Y.R.1
King, O.D.2
Shorter, J.3
Gitler, A.D.4
-
107
-
-
84944884978
-
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
-
Lin Y., Protter D.S.W., Rosen M.K., Parker R. Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins. Mol. Cell 2015, 60:208-219.
-
(2015)
Mol. Cell
, vol.60
, pp. 208-219
-
-
Lin, Y.1
Protter, D.S.W.2
Rosen, M.K.3
Parker, R.4
-
108
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
Liu L., Drouet V., Wu J.W., Witter M.P., Small S.A., Clelland C., Duff K. Trans-synaptic spread of tau pathology in vivo. PLoS ONE 2012, 7:e31302.
-
(2012)
PLoS ONE
, vol.7
, pp. e31302
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
109
-
-
84896298823
-
ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor
-
Liu-Yesucevitz L., Lin A.Y., Ebata A., Boon J.Y., Reid W., Xu Y.-F., Kobrin K., Murphy G.J., Petrucelli L., Wolozin B. ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor. J. Neurosci. 2014, 34:4167-4174.
-
(2014)
J. Neurosci.
, vol.34
, pp. 4167-4174
-
-
Liu-Yesucevitz, L.1
Lin, A.Y.2
Ebata, A.3
Boon, J.Y.4
Reid, W.5
Xu, Y.-F.6
Kobrin, K.7
Murphy, G.J.8
Petrucelli, L.9
Wolozin, B.10
-
110
-
-
84884217594
-
Molecular structure of β-amyloid fibrils in Alzheimer's disease brain tissue
-
Lu J.-X., Qiang W., Yau W.-M., Schwieters C.D., Meredith S.C., Tycko R. Molecular structure of β-amyloid fibrils in Alzheimer's disease brain tissue. Cell 2013, 154:1257-1268.
-
(2013)
Cell
, vol.154
, pp. 1257-1268
-
-
Lu, J.-X.1
Qiang, W.2
Yau, W.-M.3
Schwieters, C.D.4
Meredith, S.C.5
Tycko, R.6
-
111
-
-
84896332642
-
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes
-
Lu A., Magupalli V.G., Ruan J., Yin Q., Atianand M.K., Vos M.R., Schröder G.F., Fitzgerald K.A., Wu H., Egelman E.H. Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell 2014, 156:1193-1206.
-
(2014)
Cell
, vol.156
, pp. 1193-1206
-
-
Lu, A.1
Magupalli, V.G.2
Ruan, J.3
Yin, Q.4
Atianand, M.K.5
Vos, M.R.6
Schröder, G.F.7
Fitzgerald, K.A.8
Wu, H.9
Egelman, E.H.10
-
112
-
-
72149119358
-
Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
-
Luk K.C., Song C., O'Brien P., Stieber A., Branch J.R., Brunden K.R., Trojanowski J.Q., Lee V.M.-Y. Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells. Proc. Natl. Acad. Sci. USA 2009, 106:20051-20056.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20051-20056
-
-
Luk, K.C.1
Song, C.2
O'Brien, P.3
Stieber, A.4
Branch, J.R.5
Brunden, K.R.6
Trojanowski, J.Q.7
Lee, V.M.-Y.8
-
113
-
-
84862609075
-
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
-
Luk K.C., Kehm V.M., Zhang B., O'Brien P., Trojanowski J.Q., Lee V.M.-Y. Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice. J. Exp. Med. 2012, 209:975-986.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 975-986
-
-
Luk, K.C.1
Kehm, V.M.2
Zhang, B.3
O'Brien, P.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
114
-
-
84869109864
-
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
-
Luk K.C., Kehm V., Carroll J., Zhang B., O'Brien P., Trojanowski J.Q., Lee V.M.-Y. Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. Science 2012, 338:949-953.
-
(2012)
Science
, vol.338
, pp. 949-953
-
-
Luk, K.C.1
Kehm, V.2
Carroll, J.3
Zhang, B.4
O'Brien, P.5
Trojanowski, J.Q.6
Lee, V.M.-Y.7
-
115
-
-
84862776939
-
Critical role of amyloid-like oligomers of Drosophila Orb2 in the persistence of memory
-
Majumdar A., Cesario W.C., White-Grindley E., Jiang H., Ren F., Khan M.R., Li L., Choi E.M.-L., Kannan K., Guo F., et al. Critical role of amyloid-like oligomers of Drosophila Orb2 in the persistence of memory. Cell 2012, 148:515-529.
-
(2012)
Cell
, vol.148
, pp. 515-529
-
-
Majumdar, A.1
Cesario, W.C.2
White-Grindley, E.3
Jiang, H.4
Ren, F.5
Khan, M.R.6
Li, L.7
Choi, E.M.-L.8
Kannan, K.9
Guo, F.10
-
116
-
-
33846538022
-
Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice
-
Mallucci G.R., White M.D., Farmer M., Dickinson A., Khatun H., Powell A.D., Brandner S., Jefferys J.G.R., Collinge J. Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron 2007, 53:325-335.
-
(2007)
Neuron
, vol.53
, pp. 325-335
-
-
Mallucci, G.R.1
White, M.D.2
Farmer, M.3
Dickinson, A.4
Khatun, H.5
Powell, A.D.6
Brandner, S.7
Jefferys, J.G.R.8
Collinge, J.9
-
117
-
-
67249099366
-
Identification of an intracellular site of prion conversion
-
Marijanovic Z., Caputo A., Campana V., Zurzolo C. Identification of an intracellular site of prion conversion. PLoS Pathog. 2009, 5:e1000426.
-
(2009)
PLoS Pathog.
, vol.5
, pp. e1000426
-
-
Marijanovic, Z.1
Caputo, A.2
Campana, V.3
Zurzolo, C.4
-
118
-
-
84876057762
-
Prion-like spreading of pathological α-synuclein in brain
-
Masuda-Suzukake M., Nonaka T., Hosokawa M., Oikawa T., Arai T., Akiyama H., Mann D.M.A., Hasegawa M. Prion-like spreading of pathological α-synuclein in brain. Brain 2013, 136:1128-1138.
-
(2013)
Brain
, vol.136
, pp. 1128-1138
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Oikawa, T.4
Arai, T.5
Akiyama, H.6
Mann, D.M.A.7
Hasegawa, M.8
-
119
-
-
85048243758
-
Pathological alpha-synuclein propagates through neural networks
-
Masuda-Suzukake M., Nonaka T., Hosokawa M., Kubo M., Shimozawa A., Akiyama H., Hasegawa M. Pathological alpha-synuclein propagates through neural networks. Acta Neuropathol. Commun. 2014, 2:88.
-
(2014)
Acta Neuropathol. Commun.
, vol.2
, pp. 88
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Kubo, M.4
Shimozawa, A.5
Akiyama, H.6
Hasegawa, M.7
-
121
-
-
84892672872
-
The neuropathology of sport
-
McKee A.C., Daneshvar D.H., Alvarez V.E., Stein T.D. The neuropathology of sport. Acta Neuropathol. 2014, 127:29-51.
-
(2014)
Acta Neuropathol.
, vol.127
, pp. 29-51
-
-
McKee, A.C.1
Daneshvar, D.H.2
Alvarez, V.E.3
Stein, T.D.4
-
122
-
-
65449120034
-
Virus entry by macropinocytosis
-
Mercer J., Helenius A. Virus entry by macropinocytosis. Nat. Cell Biol. 2009, 11:510-520.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 510-520
-
-
Mercer, J.1
Helenius, A.2
-
123
-
-
84907059487
-
The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis
-
Meyer H., Weihl C.C. The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis. J. Cell Sci. 2014, 127:3877-3883.
-
(2014)
J. Cell Sci.
, vol.127
, pp. 3877-3883
-
-
Meyer, H.1
Weihl, C.C.2
-
124
-
-
33749020837
-
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host
-
Meyer-Luehmann M., Coomaraswamy J., Bolmont T., Kaeser S., Schaefer C., Kilger E., Neuenschwander A., Abramowski D., Frey P., Jaton A.L., et al. Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 2006, 313:1781-1784.
-
(2006)
Science
, vol.313
, pp. 1781-1784
-
-
Meyer-Luehmann, M.1
Coomaraswamy, J.2
Bolmont, T.3
Kaeser, S.4
Schaefer, C.5
Kilger, E.6
Neuenschwander, A.7
Abramowski, D.8
Frey, P.9
Jaton, A.L.10
-
125
-
-
84891905725
-
Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology
-
Michel C.H., Kumar S., Pinotsi D., Tunnacliffe A., St George-Hyslop P., Mandelkow E., Mandelkow E.-M., Kaminski C.F., Kaminski Schierle G.S. Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology. J. Biol. Chem. 2014, 289:956-967.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 956-967
-
-
Michel, C.H.1
Kumar, S.2
Pinotsi, D.3
Tunnacliffe, A.4
St George-Hyslop, P.5
Mandelkow, E.6
Mandelkow, E.-M.7
Kaminski, C.F.8
Kaminski Schierle, G.S.9
-
126
-
-
84931281486
-
Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation
-
Mirbaha H., Holmes B.B., Sanders D.W., Bieschke J., Diamond M.I. Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation. J. Biol. Chem. 2015, 290:14893-14903.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 14893-14903
-
-
Mirbaha, H.1
Holmes, B.B.2
Sanders, D.W.3
Bieschke, J.4
Diamond, M.I.5
-
127
-
-
84904607788
-
Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons
-
Mohamed N.-V., Plouffe V., Rémillard-Labrosse G., Planel E., Leclerc N. Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons. Sci. Rep. 2014, 4:5715.
-
(2014)
Sci. Rep.
, vol.4
, pp. 5715
-
-
Mohamed, N.-V.1
Plouffe, V.2
Rémillard-Labrosse, G.3
Planel, E.4
Leclerc, N.5
-
128
-
-
84944907005
-
Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization
-
Molliex A., Temirov J., Lee J., Coughlin M., Kanagaraj A.P., Kim H.J., Mittag T., Taylor J.P. Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization. Cell 2015, 163:123-133.
-
(2015)
Cell
, vol.163
, pp. 123-133
-
-
Molliex, A.1
Temirov, J.2
Lee, J.3
Coughlin, M.4
Kanagaraj, A.P.5
Kim, H.J.6
Mittag, T.7
Taylor, J.P.8
-
129
-
-
79952743365
-
Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
-
Münch C., O'Brien J., Bertolotti A. Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc. Natl. Acad. Sci. USA 2011, 108:3548-3553.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3548-3553
-
-
Münch, C.1
O'Brien, J.2
Bertolotti, A.3
-
130
-
-
84960129723
-
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
-
Murakami T., Qamar S., Lin J.Q., Schierle G.S.K., Rees E., Miyashita A., Costa A.R., Dodd R.B., Chan F.T.S., Michel C.H., et al. ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function. Neuron 2015, 88:678-690.
-
(2015)
Neuron
, vol.88
, pp. 678-690
-
-
Murakami, T.1
Qamar, S.2
Lin, J.Q.3
Schierle, G.S.K.4
Rees, E.5
Miyashita, A.6
Costa, A.R.7
Dodd, R.B.8
Chan, F.T.S.9
Michel, C.H.10
-
131
-
-
84939559331
-
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation
-
Nillegoda N.B., Kirstein J., Szlachcic A., Berynskyy M., Stank A., Stengel F., Arnsburg K., Gao X., Scior A., Aebersold R., et al. Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation. Nature 2015, 524:247-251.
-
(2015)
Nature
, vol.524
, pp. 247-251
-
-
Nillegoda, N.B.1
Kirstein, J.2
Szlachcic, A.3
Berynskyy, M.4
Stank, A.5
Stengel, F.6
Arnsburg, K.7
Gao, X.8
Scior, A.9
Aebersold, R.10
-
132
-
-
84923878820
-
Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles
-
Nott T.J., Petsalaki E., Farber P., Jervis D., Fussner E., Plochowietz A., Craggs T.D., Bazett-Jones D.P., Pawson T., Forman-Kay J.D., Baldwin A.J. Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles. Mol. Cell 2015, 57:936-947.
-
(2015)
Mol. Cell
, vol.57
, pp. 936-947
-
-
Nott, T.J.1
Petsalaki, E.2
Farber, P.3
Jervis, D.4
Fussner, E.5
Plochowietz, A.6
Craggs, T.D.7
Bazett-Jones, D.P.8
Pawson, T.9
Forman-Kay, J.D.10
Baldwin, A.J.11
-
133
-
-
84898684536
-
A mesoscale connectome of the mouse brain
-
Oh S.W., Harris J.A., Ng L., Winslow B., Cain N., Mihalas S., Wang Q., Lau C., Kuan L., Henry A.M., et al. A mesoscale connectome of the mouse brain. Nature 2014, 508:207-214.
-
(2014)
Nature
, vol.508
, pp. 207-214
-
-
Oh, S.W.1
Harris, J.A.2
Ng, L.3
Winslow, B.4
Cain, N.5
Mihalas, S.6
Wang, Q.7
Lau, C.8
Kuan, L.9
Henry, A.M.10
-
134
-
-
68249130677
-
Cerebrospinal fluid tau as a marker of neuronal damage after epileptic seizure
-
Palmio J., Suhonen J., Keränen T., Hulkkonen J., Peltola J., Pirttilä T. Cerebrospinal fluid tau as a marker of neuronal damage after epileptic seizure. Seizure 2009, 18:474-477.
-
(2009)
Seizure
, vol.18
, pp. 474-477
-
-
Palmio, J.1
Suhonen, J.2
Keränen, T.3
Hulkkonen, J.4
Peltola, J.5
Pirttilä, T.6
-
135
-
-
0027332116
-
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
-
Pan K.M., Baldwin M., Nguyen J., Gasset M., Serban A., Groth D., Mehlhorn I., Huang Z., Fletterick R.J., Cohen F.E., et al. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. USA 1993, 90:10962-10966.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
Baldwin, M.2
Nguyen, J.3
Gasset, M.4
Serban, A.5
Groth, D.6
Mehlhorn, I.7
Huang, Z.8
Fletterick, R.J.9
Cohen, F.E.10
-
136
-
-
84940403835
-
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
-
Patel A., Lee H.O., Jawerth L., Maharana S., Jahnel M., Hein M.Y., Stoynov S., Mahamid J., Saha S., Franzmann T.M., et al. A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation. Cell 2015, 162:1066-1077.
-
(2015)
Cell
, vol.162
, pp. 1066-1077
-
-
Patel, A.1
Lee, H.O.2
Jawerth, L.3
Maharana, S.4
Jahnel, M.5
Hein, M.Y.6
Stoynov, S.7
Mahamid, J.8
Saha, S.9
Franzmann, T.M.10
-
137
-
-
0029780647
-
Support for the prion hypothesis for inheritance of a phenotypic trait in yeast
-
Patino M.M., Liu J.J., Glover J.R., Lindquist S. Support for the prion hypothesis for inheritance of a phenotypic trait in yeast. Science 1996, 273:622-626.
-
(1996)
Science
, vol.273
, pp. 622-626
-
-
Patino, M.M.1
Liu, J.J.2
Glover, J.R.3
Lindquist, S.4
-
138
-
-
0029888121
-
Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor
-
Paushkin S.V., Kushnirov V.V., Smirnov V.N., Ter-Avanesyan M.D. Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor. EMBO J. 1996, 15:3127-3134.
-
(1996)
EMBO J.
, vol.15
, pp. 3127-3134
-
-
Paushkin, S.V.1
Kushnirov, V.V.2
Smirnov, V.N.3
Ter-Avanesyan, M.D.4
-
139
-
-
84934983329
-
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
-
Peelaerts W., Bousset L., Van der Perren A., Moskalyuk A., Pulizzi R., Giugliano M., Van den Haute C., Melki R., Baekelandt V. α-Synuclein strains cause distinct synucleinopathies after local and systemic administration. Nature 2015, 522:340-344.
-
(2015)
Nature
, vol.522
, pp. 340-344
-
-
Peelaerts, W.1
Bousset, L.2
Van der Perren, A.3
Moskalyuk, A.4
Pulizzi, R.5
Giugliano, M.6
Van den Haute, C.7
Melki, R.8
Baekelandt, V.9
-
140
-
-
84908430607
-
Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
-
Peeraer E., Bottelbergs A., Van Kolen K., Stancu I.-C., Vasconcelos B., Mahieu M., Duytschaever H., Ver Donck L., Torremans A., Sluydts E., et al. Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice. Neurobiol. Dis. 2015, 73:83-95.
-
(2015)
Neurobiol. Dis.
, vol.73
, pp. 83-95
-
-
Peeraer, E.1
Bottelbergs, A.2
Van Kolen, K.3
Stancu, I.-C.4
Vasconcelos, B.5
Mahieu, M.6
Duytschaever, H.7
Ver Donck, L.8
Torremans, A.9
Sluydts, E.10
-
141
-
-
12244249201
-
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils
-
Petkova A.T., Leapman R.D., Guo Z., Yau W.-M., Mattson M.P., Tycko R. Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science 2005, 307:262-265.
-
(2005)
Science
, vol.307
, pp. 262-265
-
-
Petkova, A.T.1
Leapman, R.D.2
Guo, Z.3
Yau, W.-M.4
Mattson, M.P.5
Tycko, R.6
-
142
-
-
84871158190
-
Hyperphosphorylation and cleavage at D421 enhance tau secretion
-
Plouffe V., Mohamed N.-V., Rivest-McGraw J., Bertrand J., Lauzon M., Leclerc N. Hyperphosphorylation and cleavage at D421 enhance tau secretion. PLoS ONE 2012, 7:e36873.
-
(2012)
PLoS ONE
, vol.7
, pp. e36873
-
-
Plouffe, V.1
Mohamed, N.-V.2
Rivest-McGraw, J.3
Bertrand, J.4
Lauzon, M.5
Leclerc, N.6
-
143
-
-
84944906590
-
Determinants of amyloid fibril degradation by the PDZ protease HTRA1
-
Poepsel S., Sprengel A., Sacca B., Kaschani F., Kaiser M., Gatsogiannis C., Raunser S., Clausen T., Ehrmann M. Determinants of amyloid fibril degradation by the PDZ protease HTRA1. Nat. Chem. Biol. 2015, 11:862-869.
-
(2015)
Nat. Chem. Biol.
, vol.11
, pp. 862-869
-
-
Poepsel, S.1
Sprengel, A.2
Sacca, B.3
Kaschani, F.4
Kaiser, M.5
Gatsogiannis, C.6
Raunser, S.7
Clausen, T.8
Ehrmann, M.9
-
144
-
-
84881531940
-
Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease
-
Polydoro M., de Calignon A., Suárez-Calvet M., Sanchez L., Kay K.R., Nicholls S.B., Roe A.D., Pitstick R., Carlson G.A., Gómez-Isla T., et al. Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease. J. Neurosci. 2013, 33:13300-13311.
-
(2013)
J. Neurosci.
, vol.33
, pp. 13300-13311
-
-
Polydoro, M.1
de Calignon, A.2
Suárez-Calvet, M.3
Sanchez, L.4
Kay, K.R.5
Nicholls, S.B.6
Roe, A.D.7
Pitstick, R.8
Carlson, G.A.9
Gómez-Isla, T.10
-
145
-
-
80155157847
-
The seeds of neurodegeneration: prion-like spreading in ALS
-
Polymenidou M., Cleveland D.W. The seeds of neurodegeneration: prion-like spreading in ALS. Cell 2011, 147:498-508.
-
(2011)
Cell
, vol.147
, pp. 498-508
-
-
Polymenidou, M.1
Cleveland, D.W.2
-
146
-
-
27744459883
-
Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease
-
Polymenidou M., Stoeck K., Glatzel M., Vey M., Bellon A., Aguzzi A. Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease. Lancet Neurol. 2005, 4:805-814.
-
(2005)
Lancet Neurol.
, vol.4
, pp. 805-814
-
-
Polymenidou, M.1
Stoeck, K.2
Glatzel, M.3
Vey, M.4
Bellon, A.5
Aguzzi, A.6
-
147
-
-
84876459364
-
Physiological release of endogenous tau is stimulated by neuronal activity
-
Pooler A.M., Phillips E.C., Lau D.H.W., Noble W., Hanger D.P. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep. 2013, 14:389-394.
-
(2013)
EMBO Rep.
, vol.14
, pp. 389-394
-
-
Pooler, A.M.1
Phillips, E.C.2
Lau, D.H.W.3
Noble, W.4
Hanger, D.P.5
-
148
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner S.B. Novel proteinaceous infectious particles cause scrapie. Science 1982, 216:136-144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
150
-
-
0032763817
-
Sporadic Creutzfeldt-Jakob disease: co-occurrence of different types of PrP(Sc) in the same brain
-
Puoti G., Giaccone G., Rossi G., Canciani B., Bugiani O., Tagliavini F. Sporadic Creutzfeldt-Jakob disease: co-occurrence of different types of PrP(Sc) in the same brain. Neurology 1999, 53:2173-2176.
-
(1999)
Neurology
, vol.53
, pp. 2173-2176
-
-
Puoti, G.1
Giaccone, G.2
Rossi, G.3
Canciani, B.4
Bugiani, O.5
Tagliavini, F.6
-
151
-
-
84858648349
-
A network diffusion model of disease progression in dementia
-
Raj A., Kuceyeski A., Weiner M. A network diffusion model of disease progression in dementia. Neuron 2012, 73:1204-1215.
-
(2012)
Neuron
, vol.73
, pp. 1204-1215
-
-
Raj, A.1
Kuceyeski, A.2
Weiner, M.3
-
152
-
-
84882801549
-
Altered ribostasis: RNA-protein granules in degenerative disorders
-
Ramaswami M., Taylor J.P., Parker R. Altered ribostasis: RNA-protein granules in degenerative disorders. Cell 2013, 154:727-736.
-
(2013)
Cell
, vol.154
, pp. 727-736
-
-
Ramaswami, M.1
Taylor, J.P.2
Parker, R.3
-
153
-
-
84868525116
-
Metazoan Hsp70 machines use Hsp110 to power protein disaggregation
-
Rampelt H., Kirstein-Miles J., Nillegoda N.B., Chi K., Scholz S.R., Morimoto R.I., Bukau B. Metazoan Hsp70 machines use Hsp110 to power protein disaggregation. EMBO J. 2012, 31:4221-4235.
-
(2012)
EMBO J.
, vol.31
, pp. 4221-4235
-
-
Rampelt, H.1
Kirstein-Miles, J.2
Nillegoda, N.B.3
Chi, K.4
Scholz, S.R.5
Morimoto, R.I.6
Bukau, B.7
-
154
-
-
84903975926
-
Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice
-
Rao M.V., McBrayer M.K., Campbell J., Kumar A., Hashim A., Sershen H., Stavrides P.H., Ohno M., Hutton M., Nixon R.A. Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice. J. Neurosci. 2014, 34:9222-9234.
-
(2014)
J. Neurosci.
, vol.34
, pp. 9222-9234
-
-
Rao, M.V.1
McBrayer, M.K.2
Campbell, J.3
Kumar, A.4
Hashim, A.5
Sershen, H.6
Stavrides, P.H.7
Ohno, M.8
Hutton, M.9
Nixon, R.A.10
-
155
-
-
34248226362
-
Implications of ALS focality: rostral-caudal distribution of lower motor neuron loss postmortem
-
Ravits J., Laurie P., Fan Y., Moore D.H. Implications of ALS focality: rostral-caudal distribution of lower motor neuron loss postmortem. Neurology 2007, 68:1576-1582.
-
(2007)
Neurology
, vol.68
, pp. 1576-1582
-
-
Ravits, J.1
Laurie, P.2
Fan, Y.3
Moore, D.H.4
-
156
-
-
34248202138
-
Focality of upper and lower motor neuron degeneration at the clinical onset of ALS
-
Ravits J., Paul P., Jorg C. Focality of upper and lower motor neuron degeneration at the clinical onset of ALS. Neurology 2007, 68:1571-1575.
-
(2007)
Neurology
, vol.68
, pp. 1571-1575
-
-
Ravits, J.1
Paul, P.2
Jorg, C.3
-
157
-
-
84897977607
-
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
-
Recasens A., Dehay B., Bové J., Carballo-Carbajal I., Dovero S., Pérez-Villalba A., Fernagut P.-O., Blesa J., Parent A., Perier C., et al. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann. Neurol. 2014, 75:351-362.
-
(2014)
Ann. Neurol.
, vol.75
, pp. 351-362
-
-
Recasens, A.1
Dehay, B.2
Bové, J.3
Carballo-Carbajal, I.4
Dovero, S.5
Pérez-Villalba, A.6
Fernagut, P.-O.7
Blesa, J.8
Parent, A.9
Perier, C.10
-
158
-
-
59649095699
-
Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
-
Ren P.-H., Lauckner J.E., Kachirskaia I., Heuser J.E., Melki R., Kopito R.R. Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates. Nat. Cell Biol. 2009, 11:219-225.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 219-225
-
-
Ren, P.-H.1
Lauckner, J.E.2
Kachirskaia, I.3
Heuser, J.E.4
Melki, R.5
Kopito, R.R.6
-
159
-
-
84885470591
-
Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice
-
Rey N.L., Petit G.H., Bousset L., Melki R., Brundin P. Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice. Acta Neuropathol. 2013, 126:555-573.
-
(2013)
Acta Neuropathol.
, vol.126
, pp. 555-573
-
-
Rey, N.L.1
Petit, G.H.2
Bousset, L.3
Melki, R.4
Brundin, P.5
-
160
-
-
3142514201
-
Protein aggregation and neurodegenerative disease
-
Ross C.A., Poirier M.A. Protein aggregation and neurodegenerative disease. Nat. Med. 2004, 10(Suppl):S10-S17.
-
(2004)
Nat. Med.
, vol.10
, pp. S10-S17
-
-
Ross, C.A.1
Poirier, M.A.2
-
161
-
-
0025840546
-
The microtubule-associated protein tau forms a triple-stranded left-hand helical polymer
-
Ruben G.C., Iqbal K., Grundke-Iqbal I., Wisniewski H.M., Ciardelli T.L., Johnson J.E. The microtubule-associated protein tau forms a triple-stranded left-hand helical polymer. J. Biol. Chem. 1991, 266:22019-22027.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 22019-22027
-
-
Ruben, G.C.1
Iqbal, K.2
Grundke-Iqbal, I.3
Wisniewski, H.M.4
Ciardelli, T.L.5
Johnson, J.E.6
-
162
-
-
0035859102
-
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
-
Saborio G.P., Permanne B., Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 2001, 411:810-813.
-
(2001)
Nature
, vol.411
, pp. 810-813
-
-
Saborio, G.P.1
Permanne, B.2
Soto, C.3
-
163
-
-
0031720905
-
Eight prion strains have PrP(Sc) molecules with different conformations
-
Safar J., Wille H., Itri V., Groth D., Serban H., Torchia M., Cohen F.E., Prusiner S.B. Eight prion strains have PrP(Sc) molecules with different conformations. Nat. Med. 1998, 4:1157-1165.
-
(1998)
Nat. Med.
, vol.4
, pp. 1157-1165
-
-
Safar, J.1
Wille, H.2
Itri, V.3
Groth, D.4
Serban, H.5
Torchia, M.6
Cohen, F.E.7
Prusiner, S.B.8
-
164
-
-
23244431836
-
Search for a prion-specific nucleic acid
-
Safar J.G., Kellings K., Serban A., Groth D., Cleaver J.E., Prusiner S.B., Riesner D. Search for a prion-specific nucleic acid. J. Virol. 2005, 79:10796-10806.
-
(2005)
J. Virol.
, vol.79
, pp. 10796-10806
-
-
Safar, J.G.1
Kellings, K.2
Serban, A.3
Groth, D.4
Cleaver, J.E.5
Prusiner, S.B.6
Riesner, D.7
-
165
-
-
84929493525
-
Structural determinants of phenotypic diversity and replication rate of human prions
-
Safar J.G., Xiao X., Kabir M.E., Chen S., Kim C., Haldiman T., Cohen Y., Chen W., Cohen M.L., Surewicz W.K. Structural determinants of phenotypic diversity and replication rate of human prions. PLoS Pathog. 2015, 11:e1004832.
-
(2015)
PLoS Pathog.
, vol.11
, pp. e1004832
-
-
Safar, J.G.1
Xiao, X.2
Kabir, M.E.3
Chen, S.4
Kim, C.5
Haldiman, T.6
Cohen, Y.7
Chen, W.8
Cohen, M.L.9
Surewicz, W.K.10
-
166
-
-
84856707794
-
Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
-
Saman S., Kim W., Raya M., Visnick Y., Miro S., Saman S., Jackson B., McKee A.C., Alvarez V.E., Lee N.C.Y., Hall G.F. Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J. Biol. Chem. 2012, 287:3842-3849.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 3842-3849
-
-
Saman, S.1
Kim, W.2
Raya, M.3
Visnick, Y.4
Miro, S.5
Saman, S.6
Jackson, B.7
McKee, A.C.8
Alvarez, V.E.9
Lee, N.C.Y.10
Hall, G.F.11
-
167
-
-
84902486430
-
Distinct tau prion strains propagate in cells and mice and define different tauopathies
-
Sanders D.W., Kaufman S.K., DeVos S.L., Sharma A.M., Mirbaha H., Li A., Barker S.J., Foley A.C., Thorpe J.R., Serpell L.C., et al. Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron 2014, 82:1271-1288.
-
(2014)
Neuron
, vol.82
, pp. 1271-1288
-
-
Sanders, D.W.1
Kaufman, S.K.2
DeVos, S.L.3
Sharma, A.M.4
Mirbaha, H.5
Li, A.6
Barker, S.J.7
Foley, A.C.8
Thorpe, J.R.9
Serpell, L.C.10
-
168
-
-
84862003756
-
Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes
-
Santa-Maria I., Varghese M., Ksiezak-Reding H., Dzhun A., Wang J., Pasinetti G.M. Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes. J. Biol. Chem. 2012, 287:20522-20533.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 20522-20533
-
-
Santa-Maria, I.1
Varghese, M.2
Ksiezak-Reding, H.3
Dzhun, A.4
Wang, J.5
Pasinetti, G.M.6
-
169
-
-
0026686855
-
Scrapie in the central nervous system: neuroanatomical spread of infection and Sinc control of pathogenesis
-
Scott J.R., Davies D., Fraser H. Scrapie in the central nervous system: neuroanatomical spread of infection and Sinc control of pathogenesis. J. Gen. Virol. 1992, 73:1637-1644.
-
(1992)
J. Gen. Virol.
, vol.73
, pp. 1637-1644
-
-
Scott, J.R.1
Davies, D.2
Fraser, H.3
-
170
-
-
33847343843
-
Dissociable intrinsic connectivity networks for salience processing and executive control
-
Seeley W.W., Menon V., Schatzberg A.F., Keller J., Glover G.H., Kenna H., Reiss A.L., Greicius M.D. Dissociable intrinsic connectivity networks for salience processing and executive control. J. Neurosci. 2007, 27:2349-2356.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2349-2356
-
-
Seeley, W.W.1
Menon, V.2
Schatzberg, A.F.3
Keller, J.4
Glover, G.H.5
Kenna, H.6
Reiss, A.L.7
Greicius, M.D.8
-
171
-
-
64149093013
-
Neurodegenerative diseases target large-scale human brain networks
-
Seeley W.W., Crawford R.K., Zhou J., Miller B.L., Greicius M.D. Neurodegenerative diseases target large-scale human brain networks. Neuron 2009, 62:42-52.
-
(2009)
Neuron
, vol.62
, pp. 42-52
-
-
Seeley, W.W.1
Crawford, R.K.2
Zhou, J.3
Miller, B.L.4
Greicius, M.D.5
-
172
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth R.B., Sun L., Ea C.-K., Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005, 122:669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.-K.3
Chen, Z.J.4
-
173
-
-
80054699747
-
The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system
-
Shorter J. The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system. PLoS ONE 2011, 6:e26319.
-
(2011)
PLoS ONE
, vol.6
, pp. e26319
-
-
Shorter, J.1
-
174
-
-
2942722444
-
Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers
-
Shorter J., Lindquist S. Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers. Science 2004, 304:1793-1797.
-
(2004)
Science
, vol.304
, pp. 1793-1797
-
-
Shorter, J.1
Lindquist, S.2
-
175
-
-
0346186101
-
A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia
-
Si K., Giustetto M., Etkin A., Hsu R., Janisiewicz A.M., Miniaci M.C., Kim J.-H., Zhu H., Kandel E.R. A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia. Cell 2003, 115:893-904.
-
(2003)
Cell
, vol.115
, pp. 893-904
-
-
Si, K.1
Giustetto, M.2
Etkin, A.3
Hsu, R.4
Janisiewicz, A.M.5
Miniaci, M.C.6
Kim, J.-H.7
Zhu, H.8
Kandel, E.R.9
-
176
-
-
0348077417
-
A neuronal isoform of the aplysia CPEB has prion-like properties
-
Si K., Lindquist S., Kandel E.R. A neuronal isoform of the aplysia CPEB has prion-like properties. Cell 2003, 115:879-891.
-
(2003)
Cell
, vol.115
, pp. 879-891
-
-
Si, K.1
Lindquist, S.2
Kandel, E.R.3
-
177
-
-
75749134925
-
Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation
-
Si K., Choi Y.-B., White-Grindley E., Majumdar A., Kandel E.R. Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation. Cell 2010, 140:421-435.
-
(2010)
Cell
, vol.140
, pp. 421-435
-
-
Si, K.1
Choi, Y.-B.2
White-Grindley, E.3
Majumdar, A.4
Kandel, E.R.5
-
178
-
-
84655176335
-
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles
-
Simón D., García-García E., Royo F., Falcón-Pérez J.M., Avila J. Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles. FEBS Lett. 2012, 586:47-54.
-
(2012)
FEBS Lett.
, vol.586
, pp. 47-54
-
-
Simón, D.1
García-García, E.2
Royo, F.3
Falcón-Pérez, J.M.4
Avila, J.5
-
179
-
-
84897474790
-
Nuclear bodies: new insights into assembly/dynamics and disease relevance
-
Sleeman J.E., Trinkle-Mulcahy L. Nuclear bodies: new insights into assembly/dynamics and disease relevance. Curr. Opin. Cell Biol. 2014, 28:76-83.
-
(2014)
Curr. Opin. Cell Biol.
, vol.28
, pp. 76-83
-
-
Sleeman, J.E.1
Trinkle-Mulcahy, L.2
-
180
-
-
0035958040
-
Internalization of transthyretin. Evidence of a novel yet unidentified receptor-associated protein (RAP)-sensitive receptor
-
Sousa M.M., Saraiva M.J. Internalization of transthyretin. Evidence of a novel yet unidentified receptor-associated protein (RAP)-sensitive receptor. J. Biol. Chem. 2001, 276:14420-14425.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14420-14425
-
-
Sousa, M.M.1
Saraiva, M.J.2
-
181
-
-
84929707383
-
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
-
Stancu I.-C., Vasconcelos B., Ris L., Wang P., Villers A., Peeraer E., Buist A., Terwel D., Baatsen P., Oyelami T., et al. Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice. Acta Neuropathol. 2015, 129:875-894.
-
(2015)
Acta Neuropathol.
, vol.129
, pp. 875-894
-
-
Stancu, I.-C.1
Vasconcelos, B.2
Ris, L.3
Wang, P.4
Villers, A.5
Peeraer, E.6
Buist, A.7
Terwel, D.8
Baatsen, P.9
Oyelami, T.10
-
182
-
-
84901599537
-
Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions
-
Stein K.C., True H.L. Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions. PLoS Genet. 2014, 10:e1004337.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004337
-
-
Stein, K.C.1
True, H.L.2
-
183
-
-
84908446907
-
Structural variants of yeast prions show conformer-specific requirements for chaperone activity
-
Stein K.C., True H.L. Structural variants of yeast prions show conformer-specific requirements for chaperone activity. Mol. Microbiol. 2014, 93:1156-1171.
-
(2014)
Mol. Microbiol.
, vol.93
, pp. 1156-1171
-
-
Stein, K.C.1
True, H.L.2
-
184
-
-
84937634032
-
The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton
-
Stephan J.S., Fioriti L., Lamba N., Colnaghi L., Karl K., Derkatch I.L., Kandel E.R. The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton. Cell Rep. 2015, 11:1772-1785.
-
(2015)
Cell Rep.
, vol.11
, pp. 1772-1785
-
-
Stephan, J.S.1
Fioriti, L.2
Lamba, N.3
Colnaghi, L.4
Karl, K.5
Derkatch, I.L.6
Kandel, E.R.7
-
185
-
-
1642633056
-
Conformational variations in an infectious protein determine prion strain differences
-
Tanaka M., Chien P., Naber N., Cooke R., Weissman J.S. Conformational variations in an infectious protein determine prion strain differences. Nature 2004, 428:323-328.
-
(2004)
Nature
, vol.428
, pp. 323-328
-
-
Tanaka, M.1
Chien, P.2
Naber, N.3
Cooke, R.4
Weissman, J.S.5
-
186
-
-
33746698975
-
The physical basis of how prion conformations determine strain phenotypes
-
Tanaka M., Collins S.R., Toyama B.H., Weissman J.S. The physical basis of how prion conformations determine strain phenotypes. Nature 2006, 442:585-589.
-
(2006)
Nature
, vol.442
, pp. 585-589
-
-
Tanaka, M.1
Collins, S.R.2
Toyama, B.H.3
Weissman, J.S.4
-
187
-
-
84954385047
-
Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau
-
Taniguchi-Watanabe S., Arai T., Kametani F., Nonaka T., Masuda-Suzukake M., Tarutani A., Murayama S., Saito Y., Arima K., Yoshida M., et al. Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau. Acta Neuropathol. 2016, 131:267-280.
-
(2016)
Acta Neuropathol.
, vol.131
, pp. 267-280
-
-
Taniguchi-Watanabe, S.1
Arai, T.2
Kametani, F.3
Nonaka, T.4
Masuda-Suzukake, M.5
Tarutani, A.6
Murayama, S.7
Saito, Y.8
Arima, K.9
Yoshida, M.10
-
188
-
-
12644272790
-
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
-
Telling G.C., Parchi P., DeArmond S.J., Cortelli P., Montagna P., Gabizon R., Mastrianni J., Lugaresi E., Gambetti P., Prusiner S.B. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science 1996, 274:2079-2082.
-
(1996)
Science
, vol.274
, pp. 2079-2082
-
-
Telling, G.C.1
Parchi, P.2
DeArmond, S.J.3
Cortelli, P.4
Montagna, P.5
Gabizon, R.6
Mastrianni, J.7
Lugaresi, E.8
Gambetti, P.9
Prusiner, S.B.10
-
189
-
-
84885463056
-
Trimeric tau is toxic to human neuronal cells at low nanomolar concentrations
-
Tian H., Davidowitz E., Lopez P., Emadi S., Moe J., Sierks M. Trimeric tau is toxic to human neuronal cells at low nanomolar concentrations. Int. J. Cell Biol. 2013, 2013:260787.
-
(2013)
Int. J. Cell Biol.
, vol.2013
, pp. 260787
-
-
Tian, H.1
Davidowitz, E.2
Lopez, P.3
Emadi, S.4
Moe, J.5
Sierks, M.6
-
190
-
-
79953245314
-
Amyloid structure: conformational diversity and consequences
-
Toyama B.H., Weissman J.S. Amyloid structure: conformational diversity and consequences. Annu. Rev. Biochem. 2011, 80:557-585.
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 557-585
-
-
Toyama, B.H.1
Weissman, J.S.2
-
191
-
-
34548615995
-
The structural basis of yeast prion strain variants
-
Toyama B.H., Kelly M.J.S., Gross J.D., Weissman J.S. The structural basis of yeast prion strain variants. Nature 2007, 449:233-237.
-
(2007)
Nature
, vol.449
, pp. 233-237
-
-
Toyama, B.H.1
Kelly, M.J.S.2
Gross, J.D.3
Weissman, J.S.4
-
192
-
-
84903441419
-
A-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration
-
Tran H.T., Chung C.H.-Y., Iba M., Zhang B., Trojanowski J.Q., Luk K.C., Lee V.M.-Y. A-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration. Cell Rep. 2014, 7:2054-2065.
-
(2014)
Cell Rep.
, vol.7
, pp. 2054-2065
-
-
Tran, H.T.1
Chung, C.H.-Y.2
Iba, M.3
Zhang, B.4
Trojanowski, J.Q.5
Luk, K.C.6
Lee, V.M.-Y.7
-
193
-
-
0034727077
-
A yeast prion provides a mechanism for genetic variation and phenotypic diversity
-
True H.L., Lindquist S.L. A yeast prion provides a mechanism for genetic variation and phenotypic diversity. Nature 2000, 407:477-483.
-
(2000)
Nature
, vol.407
, pp. 477-483
-
-
True, H.L.1
Lindquist, S.L.2
-
194
-
-
4544235083
-
Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits
-
True H.L., Berlin I., Lindquist S.L. Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits. Nature 2004, 431:184-187.
-
(2004)
Nature
, vol.431
, pp. 184-187
-
-
True, H.L.1
Berlin, I.2
Lindquist, S.L.3
-
195
-
-
84908518328
-
Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils
-
Tsujimura A., Taguchi K., Watanabe Y., Tatebe H., Tokuda T., Mizuno T., Tanaka M. Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils. Neurobiol. Dis. 2015, 73:244-253.
-
(2015)
Neurobiol. Dis.
, vol.73
, pp. 244-253
-
-
Tsujimura, A.1
Taguchi, K.2
Watanabe, Y.3
Tatebe, H.4
Tokuda, T.5
Mizuno, T.6
Tanaka, M.7
-
196
-
-
84880025984
-
Caudo-rostral brain spreading of α-synuclein through vagal connections
-
Ulusoy A., Rusconi R., Pérez-Revuelta B.I., Musgrove R.E., Helwig M., Winzen-Reichert B., Di Monte D.A. Caudo-rostral brain spreading of α-synuclein through vagal connections. EMBO Mol. Med. 2013, 5:1051-1059.
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 1051-1059
-
-
Ulusoy, A.1
Rusconi, R.2
Pérez-Revuelta, B.I.3
Musgrove, R.E.4
Helwig, M.5
Winzen-Reichert, B.6
Di Monte, D.A.7
-
197
-
-
34247578209
-
Intrinsic functional architecture in the anaesthetized monkey brain
-
Vincent J.L., Patel G.H., Fox M.D., Snyder A.Z., Baker J.T., Van Essen D.C., Zempel J.M., Snyder L.H., Corbetta M., Raichle M.E. Intrinsic functional architecture in the anaesthetized monkey brain. Nature 2007, 447:83-86.
-
(2007)
Nature
, vol.447
, pp. 83-86
-
-
Vincent, J.L.1
Patel, G.H.2
Fox, M.D.3
Snyder, A.Z.4
Baker, J.T.5
Van Essen, D.C.6
Zempel, J.M.7
Snyder, L.H.8
Corbetta, M.9
Raichle, M.E.10
-
198
-
-
53749088102
-
Pathologic prion protein infects cells by lipid-raft dependent macropinocytosis
-
Wadia J.S., Schaller M., Williamson R.A., Dowdy S.F. Pathologic prion protein infects cells by lipid-raft dependent macropinocytosis. PLoS ONE 2008, 3:e3314.
-
(2008)
PLoS ONE
, vol.3
, pp. e3314
-
-
Wadia, J.S.1
Schaller, M.2
Williamson, R.A.3
Dowdy, S.F.4
-
199
-
-
0141849458
-
Molecular and clinical classification of human prion disease
-
Wadsworth J.D.F., Hill A.F., Beck J.A., Collinge J. Molecular and clinical classification of human prion disease. Br. Med. Bull. 2003, 66:241-254.
-
(2003)
Br. Med. Bull.
, vol.66
, pp. 241-254
-
-
Wadsworth, J.D.F.1
Hill, A.F.2
Beck, J.A.3
Collinge, J.4
-
200
-
-
84937392013
-
Neurodegenerative diseases: expanding the prion concept
-
Walker L.C., Jucker M. Neurodegenerative diseases: expanding the prion concept. Annu. Rev. Neurosci. 2015, 38:87-103.
-
(2015)
Annu. Rev. Neurosci.
, vol.38
, pp. 87-103
-
-
Walker, L.C.1
Jucker, M.2
-
201
-
-
84945450480
-
Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43
-
Walker A.K., Spiller K.J., Ge G., Zheng A., Xu Y., Zhou M., Tripathy K., Kwong L.K., Trojanowski J.Q., Lee V.M.-Y. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. Acta Neuropathol. 2015, 130:643-660.
-
(2015)
Acta Neuropathol.
, vol.130
, pp. 643-660
-
-
Walker, A.K.1
Spiller, K.J.2
Ge, G.3
Zheng, A.4
Xu, Y.5
Zhou, M.6
Tripathy, K.7
Kwong, L.K.8
Trojanowski, J.Q.9
Lee, V.M.-Y.10
-
202
-
-
70349987102
-
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
-
Wang Y., Martinez-Vicente M., Krüger U., Kaushik S., Wong E., Mandelkow E.-M., Cuervo A.M., Mandelkow E. Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Hum. Mol. Genet. 2009, 18:4153-4170.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4153-4170
-
-
Wang, Y.1
Martinez-Vicente, M.2
Krüger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.-M.6
Cuervo, A.M.7
Mandelkow, E.8
-
203
-
-
1842483843
-
Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
-
Watts G.D.J., Wymer J., Kovach M.J., Mehta S.G., Mumm S., Darvish D., Pestronk A., Whyte M.P., Kimonis V.E. Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat. Genet. 2004, 36:377-381.
-
(2004)
Nat. Genet.
, vol.36
, pp. 377-381
-
-
Watts, G.D.J.1
Wymer, J.2
Kovach, M.J.3
Mehta, S.G.4
Mumm, S.5
Darvish, D.6
Pestronk, A.7
Whyte, M.P.8
Kimonis, V.E.9
-
204
-
-
84888349390
-
Transmission of multiple system atrophy prions to transgenic mice
-
Watts J.C., Giles K., Oehler A., Middleton L., Dexter D.T., Gentleman S.M., DeArmond S.J., Prusiner S.B. Transmission of multiple system atrophy prions to transgenic mice. Proc. Natl. Acad. Sci. USA 2013, 110:19555-19560.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 19555-19560
-
-
Watts, J.C.1
Giles, K.2
Oehler, A.3
Middleton, L.4
Dexter, D.T.5
Gentleman, S.M.6
DeArmond, S.J.7
Prusiner, S.B.8
-
205
-
-
0028308104
-
[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae
-
Wickner R.B. [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. Science 1994, 264:566-569.
-
(1994)
Science
, vol.264
, pp. 566-569
-
-
Wickner, R.B.1
-
206
-
-
70350134002
-
Natural and synthetic prion structure from X-ray fiber diffraction
-
Wille H., Bian W., McDonald M., Kendall A., Colby D.W., Bloch L., Ollesch J., Borovinskiy A.L., Cohen F.E., Prusiner S.B., Stubbs G. Natural and synthetic prion structure from X-ray fiber diffraction. Proc. Natl. Acad. Sci. USA 2009, 106:16990-16995.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 16990-16995
-
-
Wille, H.1
Bian, W.2
McDonald, M.3
Kendall, A.4
Colby, D.W.5
Bloch, L.6
Ollesch, J.7
Borovinskiy, A.L.8
Cohen, F.E.9
Prusiner, S.B.10
Stubbs, G.11
-
207
-
-
0003986552
-
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease
-
Wischik C.M., Novak M., Thøgersen H.C., Edwards P.C., Runswick M.J., Jakes R., Walker J.E., Milstein C., Roth M., Klug A. Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc. Natl. Acad. Sci. USA 1988, 85:4506-4510.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4506-4510
-
-
Wischik, C.M.1
Novak, M.2
Thøgersen, H.C.3
Edwards, P.C.4
Runswick, M.J.5
Jakes, R.6
Walker, J.E.7
Milstein, C.8
Roth, M.9
Klug, A.10
-
208
-
-
84940969467
-
Propagation of prions causing synucleinopathies in cultured cells
-
Woerman A.L., Stöhr J., Aoyagi A., Rampersaud R., Krejciova Z., Watts J.C., Ohyama T., Patel S., Widjaja K., Oehler A., et al. Propagation of prions causing synucleinopathies in cultured cells. Proc. Natl. Acad. Sci. USA 2015, 112:E4949-E4958.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E4949-E4958
-
-
Woerman, A.L.1
Stöhr, J.2
Aoyagi, A.3
Rampersaud, R.4
Krejciova, Z.5
Watts, J.C.6
Ohyama, T.7
Patel, S.8
Widjaja, K.9
Oehler, A.10
-
209
-
-
84876221513
-
Higher-order assemblies in a new paradigm of signal transduction
-
Wu H. Higher-order assemblies in a new paradigm of signal transduction. Cell 2013, 153:287-292.
-
(2013)
Cell
, vol.153
, pp. 287-292
-
-
Wu, H.1
-
210
-
-
84872714502
-
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons
-
Wu J.W., Herman M., Liu L., Simoes S., Acker C.M., Figueroa H., Steinberg J.I., Margittai M., Kayed R., Zurzolo C., et al. Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J. Biol. Chem. 2013, 288:1856-1870.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 1856-1870
-
-
Wu, J.W.1
Herman, M.2
Liu, L.3
Simoes, S.4
Acker, C.M.5
Figueroa, H.6
Steinberg, J.I.7
Margittai, M.8
Kayed, R.9
Zurzolo, C.10
-
211
-
-
84902215812
-
Demystifying heparan sulfate-protein interactions
-
Xu D., Esko J.D. Demystifying heparan sulfate-protein interactions. Annu. Rev. Biochem. 2014, 83:129-157.
-
(2014)
Annu. Rev. Biochem.
, vol.83
, pp. 129-157
-
-
Xu, D.1
Esko, J.D.2
-
212
-
-
84898747432
-
Structural basis for the prion-like MAVS filaments in antiviral innate immunity
-
Xu H., He X., Zheng H., Huang L.J., Hou F., Yu Z., de la Cruz M.J., Borkowski B., Zhang X., Chen Z.J., Jiang Q.X. Structural basis for the prion-like MAVS filaments in antiviral innate immunity. eLife 2014, 3:e01489.
-
(2014)
eLife
, vol.3
, pp. e01489
-
-
Xu, H.1
He, X.2
Zheng, H.3
Huang, L.J.4
Hou, F.5
Yu, Z.6
de la Cruz, M.J.7
Borkowski, B.8
Zhang, X.9
Chen, Z.J.10
Jiang, Q.X.11
-
213
-
-
80052940324
-
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
-
Yamada K., Cirrito J.R., Stewart F.R., Jiang H., Finn M.B., Holmes B.B., Binder L.I., Mandelkow E.-M., Diamond M.I., Lee V.M.-Y., Holtzman D.M. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J. Neurosci. 2011, 31:13110-13117.
-
(2011)
J. Neurosci.
, vol.31
, pp. 13110-13117
-
-
Yamada, K.1
Cirrito, J.R.2
Stewart, F.R.3
Jiang, H.4
Finn, M.B.5
Holmes, B.B.6
Binder, L.I.7
Mandelkow, E.-M.8
Diamond, M.I.9
Lee, V.M.-Y.10
Holtzman, D.M.11
-
214
-
-
84896830709
-
Neuronal activity regulates extracellular tau in vivo
-
Yamada K., Holth J.K., Liao F., Stewart F.R., Mahan T.E., Jiang H., Cirrito J.R., Patel T.K., Hochgräfe K., Mandelkow E.-M., Holtzman D.M. Neuronal activity regulates extracellular tau in vivo. J. Exp. Med. 2014, 211:387-393.
-
(2014)
J. Exp. Med.
, vol.211
, pp. 387-393
-
-
Yamada, K.1
Holth, J.K.2
Liao, F.3
Stewart, F.R.4
Mahan, T.E.5
Jiang, H.6
Cirrito, J.R.7
Patel, T.K.8
Hochgräfe, K.9
Mandelkow, E.-M.10
Holtzman, D.M.11
-
215
-
-
0034737299
-
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
-
Yamamoto A., Lucas J.J., Hen R. Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell 2000, 101:57-66.
-
(2000)
Cell
, vol.101
, pp. 57-66
-
-
Yamamoto, A.1
Lucas, J.J.2
Hen, R.3
-
216
-
-
84964959825
-
Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex
-
Published online April 14, 2015
-
Yetman M.J., Lillehaug S., Bjaalie J.G., Leergaard T.B., Jankowsky J.L. Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex. Brain Struct. Funct. 2015, Published online April 14, 2015. 10.1007/s00429-015-1040-9.
-
(2015)
Brain Struct. Funct.
-
-
Yetman, M.J.1
Lillehaug, S.2
Bjaalie, J.G.3
Leergaard, T.B.4
Jankowsky, J.L.5
-
217
-
-
84928652748
-
The multivesicular body is the major internal site of prion conversion
-
Yim Y.-I., Park B.-C., Yadavalli R., Zhao X., Eisenberg E., Greene L.E. The multivesicular body is the major internal site of prion conversion. J. Cell Sci. 2015, 128:1434-1443.
-
(2015)
J. Cell Sci.
, vol.128
, pp. 1434-1443
-
-
Yim, Y.-I.1
Park, B.-C.2
Yadavalli, R.3
Zhao, X.4
Eisenberg, E.5
Greene, L.E.6
-
218
-
-
84910669129
-
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
-
Zhang Z., Song M., Liu X., Kang S.S., Kwon I.-S., Duong D.M., Seyfried N.T., Hu W.T., Liu Z., Wang J.-Z., et al. Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease. Nat. Med. 2014, 20:1254-1262.
-
(2014)
Nat. Med.
, vol.20
, pp. 1254-1262
-
-
Zhang, Z.1
Song, M.2
Liu, X.3
Kang, S.S.4
Kwon, I.-S.5
Duong, D.M.6
Seyfried, N.T.7
Hu, W.T.8
Liu, Z.9
Wang, J.-Z.10
-
219
-
-
84944884155
-
RNA Controls PolyQ Protein Phase Transitions
-
Zhang H., Elbaum-Garfinkle S., Langdon E.M., Taylor N., Occhipinti P., Bridges A.A., Brangwynne C.P., Gladfelter A.S. RNA Controls PolyQ Protein Phase Transitions. Mol. Cell 2015, 60:220-230.
-
(2015)
Mol. Cell
, vol.60
, pp. 220-230
-
-
Zhang, H.1
Elbaum-Garfinkle, S.2
Langdon, E.M.3
Taylor, N.4
Occhipinti, P.5
Bridges, A.A.6
Brangwynne, C.P.7
Gladfelter, A.S.8
-
220
-
-
84863337784
-
Predicting regional neurodegeneration from the healthy brain functional connectome
-
Zhou J., Gennatas E.D., Kramer J.H., Miller B.L., Seeley W.W. Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron 2012, 73:1216-1227.
-
(2012)
Neuron
, vol.73
, pp. 1216-1227
-
-
Zhou, J.1
Gennatas, E.D.2
Kramer, J.H.3
Miller, B.L.4
Seeley, W.W.5
-
221
-
-
84857408200
-
Highly neurotoxic monomeric α-helical prion protein
-
Zhou M., Ottenberg G., Sferrazza G.F., Lasmézas C.I. Highly neurotoxic monomeric α-helical prion protein. Proc. Natl. Acad. Sci. USA 2012, 109:3113-3118.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 3113-3118
-
-
Zhou, M.1
Ottenberg, G.2
Sferrazza, G.F.3
Lasmézas, C.I.4
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