-
1
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada, P.V., J.H. Growdon, E.T. Hedley-Whyte, and B.T. Hyman. 1992. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology. 42:631-639. http://dx.doi.org/10.1212/WNL.42.3.631
-
(1992)
Neurology.
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-whyte, E.T.3
Hyman, B.T.4
-
2
-
-
0027451311
-
Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients
-
Bancher, C., H. Braak, P. Fischer, and K.A. Jellinger. 1993. Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients. Neurosci. Lett. 162:179-182. http://dx.doi.org/10.1016/0304-3940(93)90590-H
-
(1993)
Neurosci. Lett.
, vol.162
, pp. 179-182
-
-
Bancher, C.1
Braak, H.2
Fischer, P.3
Jellinger, K.A.4
-
3
-
-
79960809092
-
Neuronal activity regulates the regional vulnerability to amyloid-β deposition
-
Bero, A.W., P. Yan, J.H. Roh, J.R. Cirrito, F.R. Stewart, M.E. Raichle, J.-M. Lee, and D.M. Holtzman. 2011. Neuronal activity regulates the regional vulnerability to amyloid-β deposition. Nat. Neurosci. 14:750-756. http://dx.doi.org/10.1038/nn.2801
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 750-756
-
-
Bero, A.W.1
Yan, P.2
Roh, J.H.3
Cirrito, J.R.4
Stewart, F.R.5
Raichle, M.E.6
Lee, J.-M.7
Holtzman, D.M.8
-
4
-
-
0029013727
-
Staging of Alzheimer's disease-related neurofibrillary changes
-
Braak, H., and E. Braak. 1995. Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol. Aging. 16:271-278. http://dx.doi.org/10.1016/0197-4580(95)00021-6
-
(1995)
Neurobiol. Aging.
, vol.16
, pp. 271-278
-
-
Braak, H.1
Braak, E.2
-
5
-
-
79959772357
-
Human apoE isoforms differentially regulate brain amyloid- β peptide clearance
-
89ra57
-
Castellano, J.M., J. Kim, F.R. Stewart, H. Jiang, R.B. DeMattos, B.W. Patterson, A.M. Fagan, J.C. Morris, K.G. Mawuenyega, C. Cruchaga, et al. 2011. Human apoE isoforms differentially regulate brain amyloid- β peptide clearance. Sci. Transl. Med. 3:89ra57.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Castellano, J.M.1
Kim, J.2
Stewart, F.R.3
Jiang, H.4
DeMattos, R.B.5
Patterson, B.W.6
Fagan, A.M.7
Morris, J.C.8
Mawuenyega, K.G.9
Cruchaga, C.10
-
6
-
-
84864935106
-
Constitutive secretion of tau protein by an unconventional mechanism
-
Chai, X., J.L. Dage, and M. Citron. 2012. Constitutive secretion of tau protein by an unconventional mechanism. Neurobiol. Dis. 48:356-366. http://dx.doi.org/10.1016/j.nbd.2012.05.021
-
(2012)
Neurobiol. Dis.
, vol.48
, pp. 356-366
-
-
Chai, X.1
Dage, J.L.2
Citron, M.3
-
7
-
-
29144487182
-
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
-
Cirrito, J.R., K.A. Yamada, M.B. Finn, R.S. Sloviter, K.R. Bales, P.C. May, D.D. Schoepp, S.M. Paul, S. Mennerick, and D.M. Holtzman. 2005. Synaptic activity regulates interstitial fluid amyloid-β levels in vivo. Neuron. 48:913-922. http://dx.doi.org/10.1016/j.neuron.2005.10.028
-
(2005)
Neuron.
, vol.48
, pp. 913-922
-
-
Cirrito, J.R.1
Yamada, K.A.2
Finn, M.B.3
Sloviter, R.S.4
Bales, K.R.5
May, P.C.6
Schoepp, D.D.7
Paul, S.M.8
Mennerick, S.9
Holtzman, D.M.10
-
8
-
-
41549155927
-
Endocytosis is required for synaptic activity-dependent release of amyloid-β in vivo
-
Cirrito, J.R., J.-E. Kang, J. Lee, F.R. Stewart, D.K. Verges, L.M. Silverio, G. Bu, S. Mennerick, and D.M. Holtzman. 2008. Endocytosis is required for synaptic activity-dependent release of amyloid-β in vivo. Neuron. 58:42-51. http://dx.doi.org/10.1016/j.neuron.2008.02.003
-
(2008)
Neuron.
, vol.58
, pp. 42-51
-
-
Cirrito, J.R.1
Kang, J.-E.2
Lee, J.3
Stewart, F.R.4
Verges, D.K.5
Silverio, L.M.6
Bu, G.7
Mennerick, S.8
Holtzman, D.M.9
-
9
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera, F., T. Bolmont, R.A. Crowther, D. Abramowski, S. Frank, A. Probst, G. Fraser, A.K. Stalder, M. Beibel, M. Staufenbiel, et al. 2009. Transmission and spreading of tauopathy in transgenic mouse brain. Nat. Cell Biol. 11:909-913. http://dx.doi.org/10.1038/ncb1901
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
-
10
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
de Calignon, A., M. Polydoro, M. Suárez-Calvet, C. William, D.H. Adamowicz, K.J. Kopeikina, R. Pitstick, N. Sahara, K.H. Ashe, G.A. Carlson, et al. 2012. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron. 73:685-697. http://dx.doi.org/10.1016/j.neuron.2011.11.033
-
(2012)
Neuron.
, vol.73
, pp. 685-697
-
-
Calignon, D.A.1
Polydoro, M.2
Suárez-calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
Pitstick, R.7
Sahara, N.8
Ashe, K.H.9
Carlson, G.A.10
-
11
-
-
35748954923
-
The β-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy
-
Eckermann, K., M.-M. Mocanu, I. Khlistunova, J. Biernat, A. Nissen, A. Hofmann, K. Schönig, H. Bujard, A. Haemisch, E. Mandelkow, et al. 2007. The β-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy. J. Biol. Chem. 282:31755- 31765. http://dx.doi.org/10.1074/jbc.M705282200
-
(2007)
J. Biol. Chem.
, vol.282
-
-
Eckermann, K.1
Mocanu, M.-M.2
Khlistunova, I.3
Biernat, J.4
Nissen, A.5
Hofmann, A.6
Schönig, K.7
Bujard, H.8
Haemisch, A.9
Mandelkow, E.10
-
12
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost, B., R.L. Jacks, and M.I. Diamond. 2009. Propagation of tau misfolding from the outside to the inside of a cell. J. Biol. Chem. 284:12845- 12852. http://dx.doi.org/10.1074/jbc.M808759200
-
(2009)
J. Biol. Chem.
, vol.284
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
13
-
-
79955441814
-
Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles
-
Guo, J.L., and V.M.-Y. Lee. 2011. Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles. J. Biol. Chem. 286:15317-15331. http://dx.doi.org/10.1074/jbc.M110.209296
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 15317-15331
-
-
Guo, J.L.1
Lee, V.M.-Y.2
-
14
-
-
84866681445
-
Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits
-
Harris, J.A., A. Koyama, S. Maeda, K. Ho, N. Devidze, D.B. Dubal, G.-Q. Yu, E. Masliah, and L. Mucke. 2012. Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits. PLoS ONE. 7:e45881. http://dx.doi.org/10.1371/journal.pone.0045881
-
(2012)
PLoS ONE.
, vol.7
-
-
Harris, J.A.1
Koyama, A.2
Maeda, S.3
Ho, K.4
Devidze, N.5
Dubal, D.B.6
Yu, G.-Q.7
Masliah, E.8
Mucke, L.9
-
15
-
-
84885836119
-
Making the brain glow: in vivo bioluminescence imaging to study neurodegeneration
-
Hochgräfe, K., and E.-M. Mandelkow. 2013. Making the brain glow: in vivo bioluminescence imaging to study neurodegeneration. Mol. Neurobiol. 47:868-882. http://dx.doi.org/10.1007/s12035-012-8379-1
-
(2013)
Mol. Neurobiol.
, vol.47
, pp. 868-882
-
-
Hochgräfe, K.1
Mandelkow, E.-M.2
-
16
-
-
84872346089
-
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
-
Iba, M., J.L. Guo, J.D. McBride, B. Zhang, J.Q. Trojanowski, and V.M.-Y. Lee. 2013. Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy. J. Neurosci. 33:1024-1037. http://dx.doi.org/10.1523/JNEUROSCI.2642-12.2013
-
(2013)
J. Neurosci.
, vol.33
, pp. 1024-1037
-
-
Iba, M.1
Guo, J.L.2
McBride, J.D.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
17
-
-
84872379077
-
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
-
Jack, C.R. Jr., D.S. Knopman, W.J. Jagust, R.C. Petersen, M.W. Weiner, P.S. Aisen, L.M. Shaw, P. Vemuri, H.J. Wiste, S.D. Weigand, et al. 2013. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol. 12:207-216. http://dx.doi.org/10.1016/S1474-4422(12)70291-0
-
(2013)
Lancet Neurol.
, vol.12
, pp. 207-216
-
-
Jack Jr., C.R.1
Knopman, D.S.2
Jagust, W.J.3
Petersen, R.C.4
Weiner, M.W.5
Aisen, P.S.6
Shaw, L.M.7
Vemuri, P.8
Wiste, H.J.9
Weigand, S.D.10
-
18
-
-
84871141635
-
Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies
-
Karch, C.M., A.T. Jeng, and A.M. Goate. 2012. Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies. J. Biol. Chem. 287:42751-42762. http://dx.doi.org/10.1074/jbc.M112.380642
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 42751-42762
-
-
Karch, C.M.1
Jeng, A.T.2
Goate, A.M.3
-
19
-
-
84861758226
-
Trans-cellular propagation of Tau aggregation by fibrillar species
-
Kfoury, N., B.B. Holmes, H. Jiang, D.M. Holtzman, and M.I. Diamond. 2012. Trans-cellular propagation of Tau aggregation by fibrillar species. J. Biol. Chem. 287:19440-19451. http://dx.doi.org/10.1074/jbc.M112.346072
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 19440-19451
-
-
Kfoury, N.1
Holmes, B.B.2
Jiang, H.3
Holtzman, D.M.4
Diamond, M.I.5
-
20
-
-
21344456506
-
Intravesicular localization and exocytosis of β-synuclein and its aggregates
-
Lee, H.-J., S. Patel, and S.-J. Lee. 2005. Intravesicular localization and exocytosis of β-synuclein and its aggregates. J. Neurosci. 25:6016-6024. http://dx.doi.org/10.1523/JNEUROSCI.0692-05.2005
-
(2005)
J. Neurosci.
, vol.25
, pp. 6016-6024
-
-
Lee, H.-J.1
Patel, S.2
Lee, S.-J.3
-
21
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
Liu, L., V. Drouet, J.W. Wu, M.P. Witter, S.A. Small, C. Clelland, and K. Duff. 2012. Trans-synaptic spread of tau pathology in vivo. PLoS ONE. 7:e31302. http://dx.doi.org/10.1371/journal.pone.0031302
-
(2012)
PLoS ONE.
, vol.7
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
22
-
-
84869109864
-
Pathological β-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
-
Luk, K.C., V. Kehm, J. Carroll, B. Zhang, P. O'Brien, J.Q. Trojanowski, and V.M.-Y. Lee. 2012. Pathological β-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. Science. 338:949-953. http://dx.doi.org/10.1126/science.1227157
-
(2012)
Science.
, vol.338
, pp. 949-953
-
-
Luk, K.C.1
Kehm, V.2
Carroll, J.3
Zhang, B.4
O'Brien, P.5
Trojanowski, J.Q.6
Lee, V.M.-Y.7
-
23
-
-
84880527880
-
Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein
-
Maia, L.F., S.A. Kaeser, J. Reichwald, M. Hruscha, P. Martus, M. Staufenbiel, and M. Jucker. 2013. Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein. Sci. Transl. Med. 5:re2.
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Maia, L.F.1
Kaeser, S.A.2
Reichwald, J.3
Hruscha, M.4
Martus, P.5
Staufenbiel, M.6
Jucker, M.7
-
24
-
-
84879232559
-
Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission
-
Mohamed, N.-V., T. Herrou, V. Plouffe, N. Piperno, and N. Leclerc. 2013. Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission. Eur. J. Neurosci. 37:1939-1948. http://dx.doi.org/10.1111/ejn.12229
-
(2013)
Eur. J. Neurosci.
, vol.37
, pp. 1939-1948
-
-
Mohamed, N.-V.1
Herrou, T.2
Plouffe, V.3
Piperno, N.4
Leclerc, N.5
-
25
-
-
84876459364
-
Physiological release of endogenous tau is stimulated by neuronal activity
-
Pooler, A.M., E.C. Phillips, D.H.W. Lau, W. Noble, and D.P. Hanger. 2013. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep. 14:389-394. http://dx.doi.org/10.1038/embor.2013.15
-
(2013)
EMBO Rep.
, vol.14
, pp. 389-394
-
-
Pooler, A.M.1
Phillips, E.C.2
Lau, D.H.W.3
Noble, W.4
Hanger, D.P.5
-
26
-
-
77956271728
-
Analysis of proteome dynamics in the mouse brain
-
Price, J.C., S. Guan, A. Burlingame, S.B. Prusiner, and S. Ghaemmaghami. 2010. Analysis of proteome dynamics in the mouse brain. Proc. Natl. Acad. Sci. USA. 107:14508-14513. http://dx.doi.org/10.1073/pnas.1006551107
-
(2010)
Proc. Natl. Acad. Sci. USA.
, vol.107
, pp. 14508-14513
-
-
Price, J.C.1
Guan, S.2
Burlingame, A.3
Prusiner, S.B.4
Ghaemmaghami, S.5
-
27
-
-
84864382491
-
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
-
Van der Jeugd, A., K. Hochgräfe, T. Ahmed, J.M. Decker, A. Sydow, A. Hofmann, D. Wu, L. Messing, D. Balschun, R. D'Hooge, and E.-M. Mandelkow. 2012. Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau. Acta Neuropathol. 123:787-805. http://dx.doi.org/10.1007/s00401-012-0987-3
-
(2012)
Acta Neuropathol.
, vol.123
, pp. 787-805
-
-
Van Jeugd, D.A.1
Hochgräfe, K.2
Ahmed, T.3
Decker, J.M.4
Sydow, A.5
Hofmann, A.6
Wu, D.7
Messing, L.8
Balschun, D.9
D'Hooge, R.10
Mandelkow, E.-M.11
-
28
-
-
79961228576
-
Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo
-
Verges, D.K., J.L. Restivo, W.D. Goebel, D.M. Holtzman, and J.R. Cirrito. 2011. Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo. J. Neurosci. 31:11328-11337. http://dx.doi.org/10.1523/JNEUROSCI.0607-11.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 11328-11337
-
-
Verges, D.K.1
Restivo, J.L.2
Goebel, W.D.3
Holtzman, D.M.4
Cirrito, J.R.5
-
29
-
-
80052940324
-
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
-
Yamada, K., J.R. Cirrito, F.R. Stewart, H. Jiang, M.B. Finn, B.B. Holmes, L.I. Binder, E.-M. Mandelkow, M.I. Diamond, V.M.-Y. Lee, and D.M. Holtzman. 2011. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J. Neurosci. 31:13110-13117. http://dx.doi.org/10.1523/JNEUROSCI.2569-11.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 13110-13117
-
-
Yamada, K.1
Cirrito, J.R.2
Stewart, F.R.3
Jiang, H.4
Finn, M.B.5
Holmes, B.B.6
Binder, L.I.7
Mandelkow, E.-M.8
Diamond, M.I.9
Lee, V.M.-Y.10
Holtzman, D.M.11
|