-
1
-
-
2442557306
-
Molecular fingerprinting of carbohydrate structure phenotypes of three Porifera proteoglycan-like glyconectins
-
GuerardelY,Czeszak X, Sumanovski LT,Karamanos Y, PopescuO, et al. 2004. Molecular fingerprinting of carbohydrate structure phenotypes of three Porifera proteoglycan-like glyconectins. J. Biol. Chem. 279:15591-603
-
(2004)
J. Biol. Chem
, vol.279
, pp. 15591-15603
-
-
Guerardel, Y.1
Czeszak, X.2
Sumanovski, L.T.3
Karamanos, Y.4
Popescu, O.5
-
2
-
-
34547838399
-
Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): Demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans
-
Yamada S, Morimoto H, Fujisawa T, Sugahara K. 2007. Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans. Glycobiology 17:886-94
-
(2007)
Glycobiology
, vol.17
, pp. 886-894
-
-
Yamada, S.1
Morimoto, H.2
Fujisawa, T.3
Sugahara, K.4
-
3
-
-
57749107717
-
Evolutionary differences in glycosaminoglycan fine structure detected by quantitative glycan reductive isotope labeling
-
Lawrence R, Olson SK, Steele RE, Wang L, Warrior R, et al. 2008. Evolutionary differences in glycosaminoglycan fine structure detected by quantitative glycan reductive isotope labeling. J. Biol. Chem. 283:33674-84
-
(2008)
J. Biol. Chem
, vol.283
, pp. 33674-33684
-
-
Lawrence, R.1
Olson, S.K.2
Steele, R.E.3
Wang, L.4
Warrior, R.5
-
4
-
-
79957592466
-
A systems biology approach for the investigation of the heparin/heparan sulfate interactome
-
Ori A, Wilkinson MC, Fernig DG. 2011. A systems biology approach for the investigation of the heparin/heparan sulfate interactome. J. Biol. Chem. 286:19892-904
-
(2011)
J. Biol. Chem
, vol.286
, pp. 19892-19904
-
-
Ori, A.1
Wilkinson, M.C.2
Fernig, D.G.3
-
5
-
-
34247610845
-
Heparan sulphate proteoglycans fine-Tunemammalian physiology
-
Bishop JR, Schuksz M, Esko JD. 2007. Heparan sulphate proteoglycans fine-Tunemammalian physiology. Nature 446:1030-37
-
(2007)
Nature
, vol.446
, pp. 1030-1037
-
-
Bishop, J.R.1
Schuksz, M.2
Esko, J.D.3
-
6
-
-
0034663225
-
Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice
-
Lin X, Wei G, Shi ZZ, Dryer L, Esko JD, et al. 2000. Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev. Biol. 224:299-311
-
(2000)
Dev. Biol
, vol.224
, pp. 299-311
-
-
Lin, X.1
Wei, G.2
Shi, Z.Z.3
Dryer, L.4
Esko, J.D.5
-
7
-
-
28844450108
-
Mice deficient in Ext2 lack heparan sulfate and develop exostoses
-
Stickens D, Zak BM, Rougier N, Esko JD, Werb Z. 2005. Mice deficient in Ext2 lack heparan sulfate and develop exostoses. Development 132:5055-68
-
(2005)
Development
, vol.132
, pp. 5055-5068
-
-
Stickens, D.1
Zak, B.M.2
Rougier, N.3
Esko, J.D.4
Werb, Z.5
-
8
-
-
0029982564
-
-
Maccarana M, Sakura Y, Tawada A, Yoshida K, Lindahl U. 1996. J. Biol. Chem. 271:17804-10
-
(1996)
J. Biol. Chem
, vol.271
, pp. 17804-17810
-
-
Maccarana, M.1
Sakura, Y.2
Tawada, A.3
Yoshida, K.4
Lindahl, U.5
-
9
-
-
3042690685
-
-
Murphy KJ, Merry CL, Lyon M, Thompson JE, Roberts IS, Gallagher JT. 2004. J. Biol. Chem. 279:27239-45
-
(2004)
J. Biol. Chem
, vol.279
, pp. 27239-27245
-
-
Murphy, K.J.1
Merry, C.L.2
Lyon, M.3
Thompson, J.E.4
Roberts, I.S.5
Gallagher, J.T.6
-
10
-
-
0035997376
-
Order out of chaos: Assembly of ligand binding sites in heparan sulfate
-
Esko JD, Selleck SB. 2002. Order out of chaos: Assembly of ligand binding sites in heparan sulfate. Annu. Rev. Biochem. 71:435-71
-
(2002)
Annu. Rev. Biochem
, vol.71
, pp. 435-471
-
-
Esko, J.D.1
Selleck, S.B.2
-
11
-
-
84862777079
-
Disease-specific non-reducing end carbohydrate biomarkers for mucopolysaccharidoses
-
LawrenceR,Brown JR,Al-MafrajiK,LamannaWC,Beitel JR, et al. 2012. Disease-specific non-reducing end carbohydrate biomarkers for mucopolysaccharidoses. Nat. Chem. Biol. 8:197-204
-
(2012)
Nat. Chem. Biol
, vol.8
, pp. 197-204
-
-
Lawrence, R.1
Brown, J.R.2
Al-Mafraji, K.3
Lamanna, W.C.4
Beitel, J.R.5
-
13
-
-
84873024385
-
Heparan sulfate biosyn thesis: Regulation and variability
-
Kreuger J, Kjelleacute;n L. 2012. Heparan sulfate biosynthesis: regulation and variability. J. Histochem. Cytochem. 60:898-907
-
(2012)
J. Histochem. Cytochem
, vol.60
, pp. 898-907
-
-
Kreuger, J.1
Kjelleacute, L.N.2
-
14
-
-
80053022354
-
Microbial lectins: Hemagglutinins, adhesins, and toxins
-
ed. A Varki, RD Cummings, JD Esko, HH Freeze, P Stanley, et al. Cold Spring Harbor, N.Y.: Cold Spring Harb. Lab
-
Esko JD, Sharon N. 2009. Microbial lectins: hemagglutinins, adhesins, and toxins. In Essentials of Glycobiology, ed. A Varki, RD Cummings, JD Esko, HH Freeze, P Stanley, et al., pp. 489-500. Cold Spring Harbor, N.Y.: Cold Spring Harb. Lab.
-
(2009)
Essentials of Glycobiology
, pp. 489-500
-
-
Esko, J.D.1
Sharon, N.2
-
15
-
-
79952174904
-
Proteins that bind sulfated glyocosaminoglycans
-
ed. A Varki, RD Cummings, JD Esko, HH Freeze, P Stanley, et al. Cold Spring Harbor, N.Y.: Cold Spring Harb. Lab
-
Esko JD, Linhardt RJ. 2009. Proteins that bind sulfated glyocosaminoglycans. In Essentials of Glycobiology, ed. A Varki, RD Cummings, JD Esko, HH Freeze, P Stanley, et al., pp. 501-12. Cold Spring Harbor, N.Y.: Cold Spring Harb. Lab.
-
(2009)
Essentials of Glycobiology
, pp. 501-512
-
-
Esko, J.D.1
Linhardt, R.J.2
-
16
-
-
0023001195
-
Transport of heparan sulfate into the nuclei of hepatocytes
-
IshiharaM, Fedarko NS, Conrad HE. 1986. Transport of heparan sulfate into the nuclei of hepatocytes. J. Biol. Chem. 261:13575-80
-
(1986)
J. Biol. Chem
, vol.261
, pp. 13575-13580
-
-
Ishihara, M.1
Fedarko, N.S.2
Conrad, H.E.3
-
17
-
-
0034995996
-
Regulation of heparan sulfate proteoglycan nuclear localization by fibronectin
-
Richardson TP, Trinkaus-Randall V, Nugent MA. 2001. Regulation of heparan sulfate proteoglycan nuclear localization by fibronectin. J. Cell Sci. 114:1613-23
-
(2001)
J. Cell Sci
, vol.114
, pp. 1613-1623
-
-
Richardson, T.P.1
Trinkaus-Randall, V.2
Nugent, M.A.3
-
18
-
-
63349092054
-
Heparanase regulates levels of syndecan-1 in the nucleus
-
Chen L, Sanderson RD. 2009. Heparanase regulates levels of syndecan-1 in the nucleus. PLoS ONE 4:e4947
-
(2009)
PLoS ONE
, vol.4
-
-
Chen, L.1
Sanderson, R.D.2
-
19
-
-
70350038068
-
Syndecan-1 and FGF-2, but not FGF receptor-1, share a commontransport route and co-localize with heparanase in the nuclei ofmesenchymal tumor cells
-
Zong F, Fthenou E, Wolmer N, Holl ösi P,Kovalszky I, et al. 2009. Syndecan-1 and FGF-2, but not FGF receptor-1, share a commontransport route and co-localize with heparanase in the nuclei ofmesenchymal tumor cells. PLoS ONE 4:e7346
-
(2009)
PLoS ONE
, vol.4
-
-
Zong, F.1
Fthenou, E.2
Wolmer, N.3
Holl Ösi, P.4
Kovalszky, I.5
-
20
-
-
70449590867
-
Discovery and classification of glycan-binding proteins
-
ed. A Varki, RD Cummings, JD Esko, HH Freeze, P Stanley, et al. Cold Spring Harbor, N.Y.: Cold Spring Harb. Lab
-
Varki A, Etzler ME, Cummings RD, Esko JD. 2009. Discovery and classification of glycan-binding proteins. In Essentials of Glycobiology, ed. A Varki, RD Cummings, JD Esko, HH Freeze, P Stanley, et al., pp. 375-86. Cold Spring Harbor, N.Y.: Cold Spring Harb. Lab.
-
(2009)
Essentials of Glycobiology
, pp. 375-386
-
-
Varki, A.1
Etzler, M.E.2
Cummings, R.D.3
Esko, J.D.4
-
21
-
-
58449097021
-
FGF-10 and specific structural elements of dermatan sulfate size and sulfation promote maximal keratinocyte migration and cellular proliferation
-
Radek KA, Taylor KR,Gallo RL. 2009. FGF-10 and specific structural elements of dermatan sulfate size and sulfation promote maximal keratinocyte migration and cellular proliferation. Wound Repair Regen. 17:118-26
-
(2009)
Wound Repair Regen
, vol.17
, pp. 118-126
-
-
Radek, K.A.1
Taylor, K.R.2
Gallo, R.L.3
-
22
-
-
14044263531
-
Structural and sequencemotifs in dermatan sulfate for promoting fibroblast growth factor 2 (FGF-2) and FGF-7 activity
-
Taylor KR,Rudisill JA, Gallo RL. 2005. Structural and sequencemotifs in dermatan sulfate for promoting fibroblast growth factor 2 (FGF-2) and FGF-7 activity. J. Biol. Chem. 280:5300-6
-
(2005)
J. Biol. Chem
, vol.280
, pp. 5300-5306
-
-
Taylor, K.R.1
Rudisill, J.A.2
Gallo, R.L.3
-
23
-
-
0037044757
-
Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7)
-
Trowbridge JM, Rudisill JA, Ron D, Gallo RL. 2002. Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7). J. Biol. Chem. 277:42815-20
-
(2002)
J. Biol. Chem
, vol.277
, pp. 42815-42820
-
-
Trowbridge, J.M.1
Rudisill, J.A.2
Ron, D.3
Gallo, R.L.4
-
24
-
-
0036744549
-
Dermatan sulfate: New functions from an old glycosaminoglycan
-
Trowbridge JM, Gallo RL. 2002. Dermatan sulfate: new functions from an old glycosaminoglycan. Glycobiology 12:R117-25
-
(2002)
Glycobiology
, vol.12
-
-
Trowbridge, J.M.1
Gallo, R.L.2
-
25
-
-
42649106868
-
The heparanome and regulation of cell function: Structures, functions and challenges
-
Ori A, Wilkinson MC, Fernig DG. 2008. The heparanome and regulation of cell function: structures, functions and challenges. Front. Biosci. 13:4309-38
-
(2008)
Front. Biosci
, vol.13
, pp. 4309-4338
-
-
Ori, A.1
Wilkinson, M.C.2
Fernig, D.G.3
-
26
-
-
0026657360
-
Heparin-induced conformational change and activation of mucus proteinase inhibitor
-
Faller B, Mely Y, Gerard D, Bieth JG. 1992. Heparin-induced conformational change and activation of mucus proteinase inhibitor. Biochemistry 31:8285-90
-
(1992)
Biochemistry
, vol.31
, pp. 8285-8290
-
-
Faller, B.1
Mely, Y.2
Gerard, D.3
Bieth, J.G.4
-
27
-
-
0025730441
-
Quantitative characterization of the thrombin-heparin interaction. Discrimination between specific and nonspecific binding models
-
Olson ST, Halvorson HR, Björk I. 1991. Quantitative characterization of the thrombin-heparin interaction. Discrimination between specific and nonspecific binding models. J. Biol. Chem. 266:6342-52
-
(1991)
J. Biol. Chem
, vol.266
, pp. 6342-6352
-
-
Olson, S.T.1
Halvorson, H.R.2
Björk, I.3
-
28
-
-
0035968239
-
Structural and energetic characteristics of the heparin-binding site in antithrombotic protein C
-
Friedrich U, Blom AM, Dahlbck B, Villoutreix BO. 2001. Structural and energetic characteristics of the heparin-binding site in antithrombotic protein C. J. Biol. Chem. 276:24122-28
-
(2001)
J. Biol. Chem
, vol.276
, pp. 24122-24128
-
-
Friedrich, U.1
Blom, A.M.2
Dahlbck, B.3
Villoutreix, B.O.4
-
29
-
-
0028218987
-
Energetic characterization of the basic fibroblast growth factor-heparin interaction: Identification of the heparin binding domain
-
Thompson LD, Pantoliano MW, Springer BA. 1994. Energetic characterization of the basic fibroblast growth factor-heparin interaction: identification of the heparin binding domain. Biochemistry 33:3831-40
-
(1994)
Biochemistry
, vol.33
, pp. 3831-3840
-
-
Thompson, L.D.1
Pantoliano, M.W.2
Springer, B.A.3
-
30
-
-
70449408083
-
Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice
-
Stanford KI, Bishop JR, Foley EM, Gonzales JC, Niesman IR, et al. 2009. Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice. J. Clin. Investig. 119:3236-45
-
(2009)
J. Clin. Investig
, vol.119
, pp. 3236-3245
-
-
Stanford, K.I.1
Bishop, J.R.2
Foley, E.M.3
Gonzales, J.C.4
Niesman, I.R.5
-
31
-
-
0028923498
-
Thermodynamics of charged oligopeptide-heparin interactions
-
Mascotti DP, Lohman TM. 1995. Thermodynamics of charged oligopeptide-heparin interactions. Biochemistry 34:2908-15
-
(1995)
Biochemistry
, vol.34
, pp. 2908-2915
-
-
Mascotti, D.P.1
Lohman, T.M.2
-
33
-
-
84864472945
-
Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate
-
Duchesne L, Octeau V, Bearon RN, Beckett A, Prior IA, et al. 2012. Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate. PLoS Biol. 10:e1001361
-
(2012)
PLoS Biol
, vol.10
-
-
Duchesne, L.1
Octeau, V.2
Bearon, R.N.3
Beckett, A.4
Prior, I.A.5
-
34
-
-
6344284808
-
Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor 1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV
-
Sadir R, Imberty A, Baleux F, Lortat-Jacob H. 2004. Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor 1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. J. Biol. Chem. 279:43854-60
-
(2004)
J. Biol. Chem
, vol.279
, pp. 43854-43860
-
-
Sadir, R.1
Imberty, A.2
Baleux, F.3
Lortat-Jacob, H.4
-
35
-
-
0030055212
-
Heparin decreases the blood clearance of interferon-γ and increases its activity by limiting the processing of its carboxyl-Terminal sequence
-
Lortat-Jacob H, Baltzer F, Grimaud JA. 1996. Heparin decreases the blood clearance of interferon-γ and increases its activity by limiting the processing of its carboxyl-Terminal sequence. J. Biol. Chem. 271:16139-43
-
(1996)
J. Biol. Chem
, vol.271
, pp. 16139-16143
-
-
Lortat-Jacob, H.1
Baltzer, F.2
Grimaud, J.A.3
-
37
-
-
0032474837
-
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion
-
Bellaiche Y, The I, Perrimon N. 1998. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394:85-88
-
(1998)
Nature
, vol.394
, pp. 85-88
-
-
Bellaiche, Y.1
The, I.2
Perrimon, N.3
-
38
-
-
0035152025
-
Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution ofWingless
-
Baeg GH, Lin X, KhareN, Baumgartner S, PerrimonN. 2001. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution ofWingless. Development 128:87-94
-
(2001)
Development
, vol.128
, pp. 87-94
-
-
Baeg, G.H.1
Lin, X.2
Khare, N.3
Baumgartner, S.4
Perrimon, N.5
-
39
-
-
1342341864
-
Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans
-
Takei Y,Ozawa Y, SatoM,Watanabe A,TabataT. 2004. Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Development 131:73-82
-
(2004)
Development
, vol.131
, pp. 73-82
-
-
Takei, Y.1
Ozawa, Y.2
Sato, M.3
Watanabe, A.4
Tabata, T.5
-
40
-
-
14844365003
-
Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc
-
Han C, Yan D, Belenkaya TY, Lin X. 2005. Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc. Development 132:667-79
-
(2005)
Development
, vol.132
, pp. 667-679
-
-
Han, C.1
Yan, D.2
Belenkaya, T.Y.3
Lin, X.4
-
42
-
-
0032925156
-
Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
-
Carmeliet P, Ng YS, Nuyens D, Theilmeier G, Brusselmans K, et al. 1999. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat. Med. 5:495-502
-
(1999)
Nat. Med
, vol.5
, pp. 495-502
-
-
Carmeliet, P.1
Ng, Y.S.2
Nuyens, D.3
Theilmeier, G.4
Brusselmans, K.5
-
43
-
-
33751187897
-
Themolecular diversity of glycosaminoglycans shapes animal development
-
BulowHE, Hobert O. 2006. Themolecular diversity of glycosaminoglycans shapes animal development. Annu. Rev. Cell Dev. Biol. 22:375-407
-
(2006)
Annu. Rev. Cell Dev. Biol
, vol.22
, pp. 375-407
-
-
Bulow, H.E.1
Hobert, O.2
-
44
-
-
70349876852
-
The molecular basis and functional implications of chemokine interactions with heparan sulphate
-
Lortat-Jacob H. 2009. The molecular basis and functional implications of chemokine interactions with heparan sulphate. Curr. Opin. Struct. Biol. 19:543-48
-
(2009)
Curr. Opin. Struct. Biol
, vol.19
, pp. 543-548
-
-
Lortat-Jacob, H.1
-
45
-
-
84886859740
-
Live cell imaging of chemotactic dendritic cell migration in explanted mouse ear preparations
-
Weber M, Sixt M. 2013. Live cell imaging of chemotactic dendritic cell migration in explanted mouse ear preparations. Methods Mol. Biol. 1013:215-26
-
(2013)
Methods Mol. Biol
, vol.1013
, pp. 215-226
-
-
Weber, M.1
Sixt, M.2
-
47
-
-
84878942800
-
Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology
-
Belov AA, Mohammadi M. 2013. Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology. Cold Spring Harb. Perspect. Biol. 5:a015958
-
(2013)
Cold Spring Harb. Perspect. Biol
, vol.5
-
-
Belov, A.A.1
Mohammadi, M.2
-
49
-
-
0032566048
-
Structure of a heparin-linked biologically active dimer of fibroblast growth factor
-
DiGabriele AD, Lax I,Chen DI, SvahnCM, Jaye M, et al. 1998. Structure of a heparin-linked biologically active dimer of fibroblast growth factor. Nature 393:812-17
-
(1998)
Nature
, vol.393
, pp. 812-817
-
-
Digabriele, A.D.1
Lax, I.2
Chen, D.I.3
Svahn, C.M.4
Jaye, M.5
-
50
-
-
84876372433
-
Cooperative heparin-mediated oligomerization of fibroblast growth factor 1 (FGF1) precedes recruitment of FGFR2 to ternary complexes
-
Brown A, Robinson CJ, Gallagher JT, Blundell TL. 2013. Cooperative heparin-mediated oligomerization of fibroblast growth factor 1 (FGF1) precedes recruitment of FGFR2 to ternary complexes. Biophys. J. 104:1720-30
-
(2013)
Biophys. J
, vol.104
, pp. 1720-1730
-
-
Brown, A.1
Robinson, C.J.2
Gallagher, J.T.3
Blundell, T.L.4
-
51
-
-
0034718796
-
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
-
Pellegrini L, Burke DF,Von Delft F,Mulloy B, BlundellTL. 2000. Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin. Nature 407:1029-34
-
(2000)
Nature
, vol.407
, pp. 1029-1034
-
-
Pellegrini, L.1
Burke, D.F.2
Von Delft, F.3
Mulloy, B.4
Blundell, T.L.5
-
52
-
-
84856301540
-
Plasticity in interactions of fibroblast growth factor 1 (FGF1) N terminus with FGF receptors underlies promiscuity of FGF1
-
Beenken A, Eliseenkova AV, Ibrahimi OA, Olsen SK, Mohammadi M. 2012. Plasticity in interactions of fibroblast growth factor 1 (FGF1) N terminus with FGF receptors underlies promiscuity of FGF1. J. Biol. Chem. 287:3067-78
-
(2012)
J. Biol. Chem
, vol.287
, pp. 3067-3078
-
-
Beenken, A.1
Eliseenkova, A.V.2
Ibrahimi, O.A.3
Olsen, S.K.4
Mohammadi, M.5
-
53
-
-
84880555698
-
Stable RAGE-heparan sulfate complexes are essential for signal transduction
-
Xu D, Young JH, Krahn JM, Song D, Corbett KD, et al. 2013. Stable RAGE-heparan sulfate complexes are essential for signal transduction. Am. Chem. Soc. Chem. Biol. 8:1611-20
-
(2013)
Am. Chem. Soc. Chem. Biol
, vol.8
, pp. 1611-1620
-
-
Xu, D.1
Young, J.H.2
Krahn, J.M.3
Song, D.4
Corbett, K.D.5
-
54
-
-
82355181520
-
Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE)
-
Xu D, Young J, Song D, Esko JD. 2011. Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE). J. Biol. Chem. 286:41736-44
-
(2011)
J. Biol. Chem
, vol.286
, pp. 41736-41744
-
-
Xu, D.1
Young, J.2
Song, D.3
Esko, J.D.4
-
55
-
-
57649221135
-
Amyloid precursor protein trafficking, processing, and function
-
Thinakaran G, Koo EH. 2008. Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283:29615-19
-
(2008)
J. Biol. Chem
, vol.283
, pp. 29615-29619
-
-
Thinakaran, G.1
Koo, E.H.2
-
56
-
-
8144230876
-
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
-
Herms J, Anliker B, Heber S, Ring S, Fuhrmann M, et al. 2004. Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members. EMBO J. 23:4106-15
-
(2004)
EMBO J
, vol.23
, pp. 4106-4115
-
-
Herms, J.1
Anliker, B.2
Heber, S.3
Ring, S.4
Fuhrmann, M.5
-
57
-
-
27144547977
-
Homo- and heterodimerization of APP family members promotes intercellular adhesion
-
Soba P, Eggert S, Wagner K, Zentgraf H, Siehl K, et al. 2005. Homo- and heterodimerization of APP family members promotes intercellular adhesion. EMBO J. 24:3624-34
-
(2005)
EMBO J
, vol.24
, pp. 3624-3634
-
-
Soba, P.1
Eggert, S.2
Wagner, K.3
Zentgraf, H.4
Siehl, K.5
-
58
-
-
0023987430
-
Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimers disease
-
Dyrks T, Weidemann A, Multhaup G, Salbaum JM, Lemaire HG, et al. 1988. Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimers disease. EMBO J. 7:949-57
-
(1988)
EMBO J
, vol.7
, pp. 949-957
-
-
Dyrks, T.1
Weidemann, A.2
Multhaup, G.3
Salbaum, J.M.4
Lemaire, H.G.5
-
59
-
-
80051937835
-
Crystal structure of the E2 domain of amyloid precursor protein-like protein 1 in complex with sucrose octasulfate
-
Xue Y, Lee S, Wang Y, Ha Y. 2011. Crystal structure of the E2 domain of amyloid precursor protein-like protein 1 in complex with sucrose octasulfate. J. Biol. Chem. 286:29748-57
-
(2011)
J. Biol. Chem
, vol.286
, pp. 29748-29757
-
-
Xue, Y.1
Lee, S.2
Wang, Y.3
Ha, Y.4
-
60
-
-
67649366042
-
Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers
-
Gralle M, BotelhoMG, Wouters FS. 2009. Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers. J. Biol. Chem. 284:15016-25
-
(2009)
J. Biol. Chem
, vol.284
, pp. 15016-15025
-
-
Gralle, M.1
Botelho, M.G.2
Wouters, F.S.3
-
61
-
-
18844473445
-
Expression and analysis of heparinbinding regions of the amyloid precursor protein of Alzheimers disease
-
Mok SS, Sberna G, Heffernan D, Cappai R, Galatis D, et al. 1997. Expression and analysis of heparinbinding regions of the amyloid precursor protein of Alzheimers disease. FEBS Lett. 415:303-7
-
(1997)
FEBS Lett
, vol.415
, pp. 303-307
-
-
Mok, S.S.1
Sberna, G.2
Heffernan, D.3
Cappai, R.4
Galatis, D.5
-
62
-
-
79959284264
-
The E2 domains of APP and APLP1 share a conserved mode of dimerization
-
Lee S, Xue Y, Hu J, Wang Y, Liu X, et al. 2011. The E2 domains of APP and APLP1 share a conserved mode of dimerization. Biochemistry 50:5453-64
-
(2011)
Biochemistry
, vol.50
, pp. 5453-5464
-
-
Lee, S.1
Xue, Y.2
Hu, J.3
Wang, Y.4
Liu, X.5
-
63
-
-
0032945805
-
Crystal structure of theN-Terminal, growth factor-like domain of Alzheimer amyloid precursor protein
-
Rossjohn J, Cappai R, Feil SC, Henry A,McKinstry WJ, et al. 1999. Crystal structure of theN-Terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat. Struct. Biol. 6:327-31
-
(1999)
Nat. Struct. Biol
, vol.6
, pp. 327-331
-
-
Rossjohn, J.1
Cappai, R.2
Feil, S.C.3
Henry, A.4
McKinstry, W.J.5
-
64
-
-
77950385325
-
Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein
-
Dahms SO, Hoefgen S, Roeser D, Schlott B, Gührs KH, Than ME. 2010. Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein. Proc. Natl. Acad. Sci. USA 107:5381-86
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 5381-5386
-
-
Dahms, S.O.1
Hoefgen, S.2
Roeser, D.3
Schlott, B.4
Gührs, K.H.5
Than, M.E.6
-
65
-
-
80053620192
-
Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization
-
Xue Y, Lee S, Ha Y. 2011. Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization. Proc. Natl. Acad. Sci. USA 108:16229-34
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16229-16234
-
-
Xue, Y.1
Lee, S.2
Ha, Y.3
-
66
-
-
0037452728
-
Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines
-
Proudfoot AE, Handel TM, Johnson Z, Lau EK, LiWang P, et al. 2003. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc. Natl. Acad. Sci. USA 100:1885-90
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1885-1890
-
-
Proudfoot, A.E.1
Handel, T.M.2
Johnson, Z.3
Lau, E.K.4
Liwang, P.5
-
67
-
-
79952105330
-
Chemokine oligomerization and interactions with receptors and glycosaminoglycans: The role of structural dynamics in function
-
Salanga CL, Handel TM. 2011. Chemokine oligomerization and interactions with receptors and glycosaminoglycans: the role of structural dynamics in function. Exp. Cell Res. 317:590-601
-
(2011)
Exp. Cell Res
, vol.317
, pp. 590-601
-
-
Salanga, C.L.1
Handel, T.M.2
-
68
-
-
0030810177
-
Glycosaminoglycans mediate cell surface oligomerization of chemokines
-
Hoogewerf AJ, Kuschert GS, Proudfoot AE, Borlat F, Clark-Lewis I, et al. 1997. Glycosaminoglycans mediate cell surface oligomerization of chemokines. Biochemistry 36:13570-78
-
(1997)
Biochemistry
, vol.36
, pp. 13570-13578
-
-
Hoogewerf, A.J.1
Kuschert, G.S.2
Proudfoot, A.E.3
Borlat, F.4
Clark-Lewis, I.5
-
70
-
-
0032508361
-
Identification of a glycosaminoglycan binding surface on human interleukin-8
-
Kuschert GS, Hoogewerf AJ, Proudfoot AE, Chung CW, Cooke RM, et al. 1998. Identification of a glycosaminoglycan binding surface on human interleukin-8. Biochemistry 37:11193-201
-
(1998)
Biochemistry
, vol.37
, pp. 11193-11201
-
-
Kuschert, G.S.1
Hoogewerf, A.J.2
Proudfoot, A.E.3
Chung, C.W.4
Cooke, R.M.5
-
71
-
-
0028064302
-
Crystal structure of recombinant human platelet factor 4
-
Zhang X, Chen L, Bancroft DP, Lai CK, Maione TE. 1994. Crystal structure of recombinant human platelet factor 4. Biochemistry 33:8361-66
-
(1994)
Biochemistry
, vol.33
, pp. 8361-8366
-
-
Zhang, X.1
Chen, L.2
Bancroft, D.P.3
Lai, C.K.4
Maione, T.E.5
-
72
-
-
84872066189
-
Heparin oligosaccharides inhibit chemokine (CXC motif ) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif ) receptor 4 (CXCR4) N terminus
-
Ziarek JJ, Veldkamp CT, Zhang F, Murray NJ, Kartz GA, et al. 2013. Heparin oligosaccharides inhibit chemokine (CXC motif ) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif ) receptor 4 (CXCR4) N terminus. J. Biol. Chem. 288:737-46
-
(2013)
J. Biol. Chem
, vol.288
, pp. 737-746
-
-
Ziarek, J.J.1
Veldkamp, C.T.2
Zhang, F.3
Murray, N.J.4
Kartz, G.A.5
-
73
-
-
2542498611
-
Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: Implications for structure and function in vivo
-
Lau EK, Paavola CD, Johnson Z, Gaudry JP, Geretti E, et al. 2004. Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo. J. Biol. Chem. 279:22294-305
-
(2004)
J. Biol. Chem
, vol.279
, pp. 22294-22305
-
-
Lau, E.K.1
Paavola, C.D.2
Johnson, Z.3
Gaudry, J.P.4
Geretti, E.5
-
74
-
-
45149083078
-
Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms
-
Goodger SJ, Robinson CJ, Murphy KJ, Gasiunas N, Harmer NJ, et al. 2008. Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms. J. Biol. Chem. 283:13001-8
-
(2008)
J. Biol. Chem
, vol.283
, pp. 13001-13008
-
-
Goodger, S.J.1
Robinson, C.J.2
Murphy, K.J.3
Gasiunas, N.4
Harmer, N.J.5
-
75
-
-
42949124644
-
Heparin-induced cisand trans-dimerization modes of the thrombospondin-1N-Terminal domain
-
Tan K, Duquette M, Liu JH, Shanmugasundaram K, Joachimiak A, et al. 2008. Heparin-induced cisand trans-dimerization modes of the thrombospondin-1N- Terminal domain. J. Biol. Chem. 283:3932-41
-
(2008)
J. Biol. Chem
, vol.283
, pp. 3932-3941
-
-
Tan, K.1
Duquette, M.2
Liu, J.H.3
Shanmugasundaram, K.4
Joachimiak, A.5
-
76
-
-
0035887033
-
Crystal structures ofNK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor
-
Lietha D, Chirgadze DY, Mulloy B, Blundell TL, Gherardi E. 2001. Crystal structures ofNK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. EMBO J. 20:5543-55
-
(2001)
EMBO J
, vol.20
, pp. 5543-5555
-
-
Lietha, D.1
Chirgadze, D.Y.2
Mulloy, B.3
Blundell, T.L.4
Gherardi, E.5
-
77
-
-
34547520925
-
Structural basis for ligand and heparin binding to neuropilin B domains
-
Vander Kooi CW, Jusino MA, Perman B, Neau DB, Bellamy HD, Leahy DJ. 2007. Structural basis for ligand and heparin binding to neuropilin B domains. Proc. Natl. Acad. Sci. USA 104:6152-57
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6152-6157
-
-
Vander Kooi, C.W.1
Jusino, M.A.2
Perman, B.3
Neau, D.B.4
Bellamy, H.D.5
Leahy, D.J.6
-
78
-
-
79955470793
-
Proteoglycan-specific molecular switch for RPTPclustering and neuronal extension
-
Coles CH, Shen Y, Tenney AP, Siebold C, Sutton GC, et al. 2011. Proteoglycan-specific molecular switch for RPTPclustering and neuronal extension. Science 332:484-88
-
(2011)
Science
, vol.332
, pp. 484-488
-
-
Coles, C.H.1
Shen, Y.2
Tenney, A.P.3
Siebold, C.4
Sutton, G.C.5
-
79
-
-
58149083028
-
Scaffold proteins and immune-cell signalling
-
Shaw AS, Filbert EL. 2009. Scaffold proteins and immune-cell signalling. Nat. Rev. Immunol. 9:47-56
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 47-56
-
-
Shaw, A.S.1
Filbert, E.L.2
-
81
-
-
34250787144
-
Serpins in thrombosis, hemostasis and fibrinolysis
-
Rau JC, Beaulieu LM, Huntington JA, Church FC. 2007. Serpins in thrombosis, hemostasis and fibrinolysis. J. Thromb. Haemost. 5(Suppl. 1):102-15
-
(2007)
J. Thromb. Haemost
, vol.5 SUPPL. 1
, pp. 102-115
-
-
Rau, J.C.1
Beaulieu, L.M.2
Huntington, J.A.3
Church, F.C.4
-
82
-
-
0020457447
-
Mechanism of the anticoagulant action of heparin
-
Björk I, Lindahl U. 1982. Mechanism of the anticoagulant action of heparin. Mol. Cell Biochem. 48:161-82
-
(1982)
Mol. Cell Biochem
, vol.48
, pp. 161-182
-
-
Björk, I.1
Lindahl, U.2
-
83
-
-
0025831251
-
Predominant contribution of surface approximation to the mechanism of heparin acceleration of the antithrombin-Thrombin reaction. Elucidation from salt concentration effects
-
Olson ST, Björk I. 1991. Predominant contribution of surface approximation to the mechanism of heparin acceleration of the antithrombin-Thrombin reaction. Elucidation from salt concentration effects. J. Biol. Chem. 266:6353-64
-
(1991)
J. Biol. Chem
, vol.266
, pp. 6353-6364
-
-
Olson, S.T.1
Björk, I.2
-
84
-
-
4344590703
-
Structure of the antithrombin-Thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin
-
Li W, Johnson DJ, Esmon CT, Huntington JA. 2004. Structure of the antithrombin-Thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. Nat. Struct. Mol. Biol. 11:857-62
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 857-862
-
-
Li, W.1
Johnson, D.J.2
Esmon, C.T.3
Huntington, J.A.4
-
85
-
-
0024456056
-
Anti-Thrombin activities of heparin. Effect of saccharide chain length on thrombin inhibition by heparin cofactor II and by antithrombin
-
Bray B, Lane DA, Freyssinet JM, Pejler G, Lindahl U. 1989. Anti-Thrombin activities of heparin. Effect of saccharide chain length on thrombin inhibition by heparin cofactor II and by antithrombin. Biochem. J. 262:225-32
-
(1989)
Biochem. J
, vol.262
, pp. 225-232
-
-
Bray, B.1
Lane, D.A.2
Freyssinet, J.M.3
Pejler, G.4
Lindahl, U.5
-
86
-
-
33646581724
-
Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation
-
Johnson DJ, Li W, Adams TE, Huntington JA. 2006. Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation. EMBO J. 25:2029-37
-
(2006)
EMBO J
, vol.25
, pp. 2029-2037
-
-
Johnson, D.J.1
Li, W.2
Adams, T.E.3
Huntington, J.A.4
-
87
-
-
13244270050
-
Crystal structure of thrombin bound to heparin
-
Carter WJ, Cama E, Huntington JA. 2005. Crystal structure of thrombin bound to heparin. J. Biol. Chem. 280:2745-49
-
(2005)
J. Biol. Chem
, vol.280
, pp. 2745-2749
-
-
Carter, W.J.1
Cama, E.2
Huntington, J.A.3
-
88
-
-
4344710558
-
The ternary complex of antithrombin- anhydrothrombin-heparin reveals the basis of inhibitor specificity
-
Dementiev A, Petitou M, Herbert JM, Gettins PG. 2004. The ternary complex of antithrombin- anhydrothrombin-heparin reveals the basis of inhibitor specificity. Nat. Struct. Mol. Biol. 11:863-67
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 863-867
-
-
Dementiev, A.1
Petitou, M.2
Herbert, J.M.3
Gettins, P.G.4
-
89
-
-
0032126936
-
Contribution of basic residues of theDandHhelices in heparin binding to protein C inhibitor
-
Neese LL, Wolfe CA, Church FC. 1998. Contribution of basic residues of theDandHhelices in heparin binding to protein C inhibitor. Arch. Biochem. Biophys. 355:101-8
-
(1998)
Arch. Biochem. Biophys
, vol.355
, pp. 101-108
-
-
Neese, L.L.1
Wolfe, C.A.2
Church, F.C.3
-
90
-
-
42449150052
-
Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-Astructure of the heparin-bridged complex
-
LiW,AdamsTE, Nangalia J, EsmonCT, Huntington JA. 2008. Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-Astructure of the heparin-bridged complex. Proc. Natl. Acad. Sci. USA 105:4661-66
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4661-4666
-
-
Li, W.1
Adams, T.E.2
Nangalia, J.3
Esmon, C.T.4
Huntington, J.A.5
-
91
-
-
0037076527
-
Contribution of basic residues of the 70-80-loop to heparin binding and anticoagulant function of activated protein C
-
Yang L, Manithody C, Rezaie AR. 2002. Contribution of basic residues of the 70-80-loop to heparin binding and anticoagulant function of activated protein C. Biochemistry 41:6149-57
-
(2002)
Biochemistry
, vol.41
, pp. 6149-6157
-
-
Yang, L.1
Manithody, C.2
Rezaie, A.R.3
-
92
-
-
58149104094
-
The heparin binding site of protein C inhibitor is protease-dependent
-
Li W, Huntington JA. 2008. The heparin binding site of protein C inhibitor is protease-dependent. J. Biol. Chem. 283:36039-45
-
(2008)
J. Biol. Chem
, vol.283
, pp. 36039-36045
-
-
Li, W.1
Huntington, J.A.2
-
93
-
-
1942470528
-
Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly
-
Ibrahimi OA, Zhang F, Hrstka SC, Mohammadi M, Linhardt RJ. 2004. Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly. Biochemistry 43:4724-30
-
(2004)
Biochemistry
, vol.43
, pp. 4724-4730
-
-
Ibrahimi, O.A.1
Zhang, F.2
Hrstka, S.C.3
Mohammadi, M.4
Linhardt, R.J.5
-
94
-
-
84855775666
-
The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition
-
Kalinina J,Dutta K, IlghariD, Beenken A,Goetz R, et al. 2012. The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition. Structure 20:77-88
-
(2012)
Structure
, vol.20
, pp. 77-88
-
-
Kalinina, J.1
Dutta, K.2
Ilghari, D.3
Beenken, A.4
Goetz, R.5
-
95
-
-
0037047348
-
Fibroblast growth factor receptors 1 and 2 interact differently with heparin/heparan sulfate: Implications for dynamic assembly of a ternary signaling complex
-
Powell AK, Fernig DG, Turnbull JE. 2002. Fibroblast growth factor receptors 1 and 2 interact differently with heparin/heparan sulfate: implications for dynamic assembly of a ternary signaling complex. J. Biol. Chem. 277:28554-63
-
(2002)
J. Biol. Chem
, vol.277
, pp. 28554-28563
-
-
Powell, A.K.1
Fernig, D.G.2
Turnbull, J.E.3
-
96
-
-
0033635299
-
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization
-
Schlessinger J, Plotnikov AN, Ibrahimi OA, Eliseenkova AV, Yeh BK, et al. 2000. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol. Cell 6:743-50
-
(2000)
Mol. Cell
, vol.6
, pp. 743-750
-
-
Schlessinger, J.1
Plotnikov, A.N.2
Ibrahimi, O.A.3
Eliseenkova, A.V.4
Yeh, B.K.5
-
97
-
-
29644438840
-
Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1FGFR2cheparin ternary complexes
-
Robinson CJ, Harmer NJ, Goodger SJ, Blundell TL, Gallagher JT. 2005. Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1FGFR2cheparin ternary complexes. J. Biol. Chem. 280:42274-82
-
(2005)
J. Biol. Chem
, vol.280
, pp. 42274-42282
-
-
Robinson, C.J.1
Harmer, N.J.2
Goodger, S.J.3
Blundell, T.L.4
Gallagher, J.T.5
-
98
-
-
30944448671
-
Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
-
Olsen SK, Li JY, Bromleigh C, Eliseenkova AV, Ibrahimi OA, et al. 2006. Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain. Genes Dev. 20:185-98
-
(2006)
Genes Dev
, vol.20
, pp. 185-198
-
-
Olsen, S.K.1
Li, J.Y.2
Bromleigh, C.3
Eliseenkova, A.V.4
Ibrahimi, O.A.5
-
99
-
-
47049089676
-
Structural and functional analysis of slit and heparin binding to immunoglobulin-like domains 1 and 2 of Drosophila Robo
-
Fukuhara N, Howitt JA, Hussain SA, Hohenester E. 2008. Structural and functional analysis of slit and heparin binding to immunoglobulin-like domains 1 and 2 of Drosophila Robo. J. Biol. Chem. 283:16226-34
-
(2008)
J. Biol. Chem
, vol.283
, pp. 16226-16234
-
-
Fukuhara, N.1
Howitt, J.A.2
Hussain, S.A.3
Hohenester, E.4
-
100
-
-
68149157248
-
The origin of allosteric functional modulation: Multiple pre-existing pathways
-
del Sol A, Tsai CJ, Ma B, Nussinov R. 2009. The origin of allosteric functional modulation: multiple pre-existing pathways. Structure 17:1042-50
-
(2009)
Structure
, vol.17
, pp. 1042-1050
-
-
Del Sol, A.1
Tsai, C.J.2
Ma, B.3
Nussinov, R.4
-
101
-
-
41149104308
-
Allostery: Absence of a change in shape does not imply that allostery is not at play
-
Tsai CJ, del Sol A,Nussinov R. 2008. Allostery: Absence of a change in shape does not imply that allostery is not at play. J. Mol. Biol. 378:1-11
-
(2008)
J. Mol. Biol
, vol.378
, pp. 1-11
-
-
Tsai, C.J.1
Del Sol, A.2
Nussinov, R.3
-
102
-
-
60849096635
-
The critical role of hinge-region expulsion in the induced-fit heparin binding mechanism of antithrombin
-
Langdown J, Belzar KJ, SavoryWJ, Baglin TP, Huntington JA. 2009. The critical role of hinge-region expulsion in the induced-fit heparin binding mechanism of antithrombin. J. Mol. Biol. 386:1278-89
-
(2009)
J. Mol. Biol
, vol.386
, pp. 1278-1289
-
-
Langdown, J.1
Belzar, K.J.2
Savory, W.J.3
Baglin, T.P.4
Huntington, J.A.5
-
103
-
-
0031445112
-
The anticoagulant activation of antithrombin by heparin
-
Jin L, Abrahams JP, Skinner R, Petitou M, Pike RN, Carrell RW. 1997. The anticoagulant activation of antithrombin by heparin. Proc. Natl. Acad. Sci. USA 94:14683-88
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14683-14688
-
-
Jin, L.1
Abrahams, J.P.2
Skinner, R.3
Petitou, M.4
Pike, R.N.5
Carrell, R.W.6
-
104
-
-
76249089297
-
Molecular basis of factor IXa recognition by heparinactivated antithrombin revealed by a 1.7-Astructure of the ternary complex
-
Johnson DJ, Langdown J, Huntington JA. 2010. Molecular basis of factor IXa recognition by heparinactivated antithrombin revealed by a 1.7-Astructure of the ternary complex. Proc. Natl. Acad. Sci. USA 107:645-50
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 645-650
-
-
Johnson, D.J.1
Langdown, J.2
Huntington, J.A.3
-
105
-
-
0035957188
-
Vaccinia virus complement control protein is capable of protecting xenoendothelial cells from antibody binding and killing by human complement and cytotoxic cells
-
Al-Mohanna F, Parhar R, Kotwal GJ. 2001. Vaccinia virus complement control protein is capable of protecting xenoendothelial cells from antibody binding and killing by human complement and cytotoxic cells. Transplantation 71:796-801
-
(2001)
Transplantation
, vol.71
, pp. 796-801
-
-
Al-Mohanna, F.1
Parhar, R.2
Kotwal, G.J.3
-
106
-
-
84862183665
-
Bivalent and co-operative binding of complement factor H to heparan sulfate and heparin
-
Khan S, Nan R, Gor J, Mulloy B, Perkins SJ. 2012. Bivalent and co-operative binding of complement factor H to heparan sulfate and heparin. Biochem. J. 444:417-28
-
(2012)
Biochem. J
, vol.444
, pp. 417-428
-
-
Khan, S.1
Nan, R.2
Gor, J.3
Mulloy, B.4
Perkins, S.J.5
-
107
-
-
2942650136
-
Structure of Vaccinia complement protein in complex with heparin and potential implications for complement regulation
-
Ganesh VK, Smith SA, Kotwal GJ, Murthy KH. 2004. Structure of Vaccinia complement protein in complex with heparin and potential implications for complement regulation. Proc. Natl. Acad. Sci. USA 101:8924-29
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8924-8929
-
-
Ganesh, V.K.1
Smith, S.A.2
Kotwal, G.J.3
Murthy, K.H.4
-
108
-
-
0035951426
-
Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans
-
Murthy KHM, Smith SA, Ganesh VK, Judge KW,Mullin N, et al. 2001. Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans. Cell 104:301-11
-
(2001)
Cell
, vol.104
, pp. 301-311
-
-
Khm, M.1
Smith, S.A.2
Ganesh, V.K.3
Judge, K.W.4
Mullin, N.5
-
109
-
-
0025314311
-
Discrimination between activators and nonactivators of the alternative pathway of complement: Regulation via a sialic acid/polyanion binding site on factor H
-
Meri S, Pangburn MK. 1990. Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H. Proc. Natl. Acad. Sci. USA 87:3982-86
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3982-3986
-
-
Meri, S.1
Pangburn, M.K.2
-
110
-
-
33746614761
-
Interactions between heparan sulfate and proteins: The concept of specificity
-
Kreuger J, Spillmann D, Li JP, Lindahl U. 2006. Interactions between heparan sulfate and proteins: the concept of specificity. J. Cell Biol. 174:323-27
-
(2006)
J. Cell Biol
, vol.174
, pp. 323-327
-
-
Kreuger, J.1
Spillmann, D.2
Li, J.P.3
Lindahl, U.4
-
111
-
-
70149088868
-
Interactions between heparan sulfate and proteins-design and functional implications
-
Lindahl U, Li JP. 2009. Interactions between heparan sulfate and proteins-design and functional implications. Int. Rev. Cell Mol. Biol. 276:105-59
-
(2009)
Int. Rev. Cell Mol. Biol
, vol.276
, pp. 105-159
-
-
Lindahl, U.1
Li, J.P.2
-
112
-
-
70350442571
-
The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation
-
Richard B, Swanson R, Olson ST. 2009. The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation. J. Biol. Chem. 284:27054-64
-
(2009)
J. Biol. Chem
, vol.284
, pp. 27054-27064
-
-
Richard, B.1
Swanson, R.2
Olson, S.T.3
-
113
-
-
0026727774
-
Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate
-
Turnbull JE, Fernig DG, Ke Y, WilkinsonMC, Gallagher JT. 1992. Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate. J. Biol. Chem. 267:10337-41
-
(1992)
J. Biol. Chem
, vol.267
, pp. 10337-10341
-
-
Turnbull, J.E.1
Fernig, D.G.2
Ke, Y.3
Wilkinson, M.C.4
Gallagher, J.T.5
-
114
-
-
0029051004
-
Molecular organization of the interferon γ-binding domain in heparan sulphate
-
Lortat-Jacob H, Turnbull JE, Grimaud JA. 1995. Molecular organization of the interferon γ-binding domain in heparan sulphate. Biochem. J. 310:497-505
-
(1995)
Biochem. J
, vol.310
, pp. 497-505
-
-
Lortat-Jacob, H.1
Turnbull, J.E.2
Grimaud, J.A.3
-
115
-
-
0032546954
-
Defining the interleukin-8-binding domain of heparan sulfate
-
Spillmann D,Witt D, Lindahl U. 1998. Defining the interleukin-8-binding domain of heparan sulfate. J. Biol. Chem. 273:15487-93
-
(1998)
J. Biol. Chem
, vol.273
, pp. 15487-15493
-
-
Spillmann, D.1
Witt, D.2
Lindahl, U.3
-
116
-
-
33748527145
-
Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling
-
Kamimura K, Koyama T, Habuchi H, Ueda R, Masu M, et al. 2006. Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling. J. Cell Biol. 174:773-78
-
(2006)
J. Cell Biol
, vol.174
, pp. 773-778
-
-
Kamimura, K.1
Koyama, T.2
Habuchi, H.3
Ueda, R.4
Masu, M.5
-
117
-
-
0033582432
-
Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities
-
Liu J, Shworak NW, Sinay P, Schwartz JJ, Zhang L, et al. 1999. Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities. J. Biol. Chem. 274:5185-92
-
(1999)
J. Biol. Chem
, vol.274
, pp. 5185-5192
-
-
Liu, J.1
Shworak, N.W.2
Sinay, P.3
Schwartz, J.J.4
Zhang, L.5
-
118
-
-
84883257965
-
Differential roles for 3-OSTs in the regulation of cilia length and motility
-
Neugebauer JM, Cadwallader AB, Amack JD, Bisgrove BW, YostHJ. 2013. Differential roles for 3-OSTs in the regulation of cilia length and motility. Development 140:3892-902
-
(2013)
Development
, vol.140
, pp. 3892-3902
-
-
Neugebauer, J.M.1
Cadwallader, A.B.2
Amack, J.D.3
Bisgrove, B.W.4
Yost, H.J.5
-
119
-
-
0037163107
-
Biosynthetic oligosaccharide libraries for identification of protein-binding heparan sulfate motifs-exploring the structural diversity by screening for fibroblast growth factor (FGF) 1 and FGF2 binding
-
Jemth P, Kreuger J, Kusche-Gullberg M, Sturiale L, Gimnez-Gallego G, Lindahl U. 2002. Biosynthetic oligosaccharide libraries for identification of protein-binding heparan sulfate motifs-exploring the structural diversity by screening for fibroblast growth factor (FGF) 1 and FGF2 binding. J. Biol. Chem. 277:30567-73
-
(2002)
J. Biol. Chem
, vol.277
, pp. 30567-30573
-
-
Jemth, P.1
Kreuger, J.2
Kusche-Gullberg, M.3
Sturiale, L.4
Gimnez-Gallego, G.5
Lindahl, U.6
-
120
-
-
0029866647
-
Heparin structure and interactions with basic fibroblast growth factor
-
Faham S, Hileman RE, Fromm JR, Linhardt RJ, Rees DC. 1996. Heparin structure and interactions with basic fibroblast growth factor. Science 271:1116-20
-
(1996)
Science
, vol.271
, pp. 1116-1120
-
-
Faham, S.1
Hileman, R.E.2
Fromm, J.R.3
Linhardt, R.J.4
Rees, D.C.5
-
121
-
-
0032483520
-
-
Pye DA, Vives RR, Turnbull JE, Hyde P, Gallagher JT. 1998. J. Biol. Chem. 273:22936-42
-
(1998)
J. Biol. Chem
, vol.273
, pp. 22936-22942
-
-
Pye, D.A.1
Vives, R.R.2
Turnbull, J.E.3
Hyde, P.4
Gallagher, J.T.5
-
124
-
-
84863879494
-
Strategies in synthesis of heparin/heparan sulfate oligosaccharides 2000- present
-
Dulaney SB, Huang X. 2012. Strategies in synthesis of heparin/heparan sulfate oligosaccharides: 2000- present. Adv. Carbohydr. Chem. Biochem. 67:95-136
-
(2012)
Adv. Carbohydr. Chem. Biochem
, vol.67
, pp. 95-136
-
-
Dulaney, S.B.1
Huang, X.2
-
125
-
-
0025783711
-
Sequence analysis of heparan sulphate indicates defined location of N-sulphated glucosamine and iduronate 2-sulphate residues proximal to the protein-linkage region
-
Turnbull JE, Gallagher JT. 1991. Sequence analysis of heparan sulphate indicates defined location of N-sulphated glucosamine and iduronate 2-sulphate residues proximal to the protein-linkage region. Biochem. J. 277:297-303
-
(1991)
Biochem. J
, vol.277
, pp. 297-303
-
-
Turnbull, J.E.1
Gallagher, J.T.2
-
126
-
-
0030796217
-
Specific binding of the chemokine platelet factor 4 to heparan sulfate
-
Stringer SE, Gallagher JT. 1997. Specific binding of the chemokine platelet factor 4 to heparan sulfate. J. Biol. Chem. 272:20508-14
-
(1997)
J. Biol. Chem
, vol.272
, pp. 20508-20514
-
-
Stringer, S.E.1
Gallagher, J.T.2
-
127
-
-
0036721004
-
Characterization of the binding site on heparan sulfate for macrophage inflammatory protein 1alpha;
-
Stringer SE, Forster MJ, Mulloy B, Bishop CR, Graham GJ, Gallagher JT. 2002. Characterization of the binding site on heparan sulfate for macrophage inflammatory protein 1alpha;. Blood 100:1543-50
-
(2002)
Blood
, vol.100
, pp. 1543-1550
-
-
Stringer, S.E.1
Forster, M.J.2
Mulloy, B.3
Bishop, C.R.4
Graham, G.J.5
Gallagher, J.T.6
-
128
-
-
84865440249
-
Inactivation of heparan sulfate 2- O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice
-
Axelsson J, XuD,Na Kang B,Nussbacher JK,Handel TM, et al. 2012. Inactivation of heparan sulfate 2- O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice. Blood 120:1742-51
-
(2012)
Blood
, vol.120
, pp. 1742-1751
-
-
Axelsson, J.1
Xu, D.2
Na Kang, B.3
Nussbacher, J.K.4
Handel, T.M.5
-
129
-
-
0042829441
-
Endothelial inflammation: The role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate
-
Carter NM, Ali S, Kirby JA. 2003. Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate. J. Cell Sci. 116:3591-600
-
(2003)
J. Cell Sci
, vol.116
, pp. 3591-3600
-
-
Carter, N.M.1
Ali, S.2
Kirby, J.A.3
-
130
-
-
50849102274
-
Glycanogenomics: A qPCR-Approach to investigate biological glycan function
-
Krenn EC, Wille I, Gesslbauer B, Poteser M, van Kuppevelt TH, Kungl AJ. 2008. Glycanogenomics: A qPCR-Approach to investigate biological glycan function. Biochem. Biophys. Res. Commun. 375:297-302
-
(2008)
Biochem. Biophys. Res. Commun
, vol.375
, pp. 297-302
-
-
Krenn, E.C.1
Wille, I.2
Gesslbauer, B.3
Poteser, M.4
Van Kuppevelt, T.H.5
Kungl, A.J.6
-
131
-
-
41949105981
-
Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density
-
Catlow KR,Deakin JA, Wei Z,Delehedde M, Fernig DG, et al. 2008. Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. J. Biol. Chem. 283:5235-48
-
(2008)
J. Biol. Chem
, vol.283
, pp. 5235-5248
-
-
Catlow, K.R.1
Deakin, J.A.2
Wei, Z.3
Delehedde, M.4
Fernig, D.G.5
-
132
-
-
70450208952
-
The heparin-binding domain confers diverse functions ofVEGF-A in development and disease: A structure-function study
-
Krilleke D, Ng YS, Shima DT. 2009. The heparin-binding domain confers diverse functions ofVEGF-A in development and disease: A structure-function study. Biochem. Soc. Trans. 37:1201-6
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 1201-1206
-
-
Krilleke, D.1
Ng, Y.S.2
Shima, D.T.3
-
133
-
-
33845968160
-
Crystallographic analysis of calcium-dependent heparin binding to annexin A2
-
Shao C, Zhang F, Kemp MM, Linhardt RJ, Waisman DM, et al. 2006. Crystallographic analysis of calcium-dependent heparin binding to annexin A2. J. Biol. Chem. 281:31689-95
-
(2006)
J. Biol. Chem
, vol.281
, pp. 31689-31695
-
-
Shao, C.1
Zhang, F.2
Kemp, M.M.3
Linhardt, R.J.4
Waisman, D.M.5
-
134
-
-
0033026762
-
Interaction of heparin with annexin v
-
Capila I, VanderNoot VA,Mealy TR, Seaton BA, Linhardt RJ. 1999. Interaction of heparin with annexin V. FEBS Lett. 446:327-30
-
(1999)
FEBS Lett
, vol.446
, pp. 327-330
-
-
Capila, I.1
Vander Noot, V.A.2
Mealy, T.R.3
Seaton, B.A.4
Linhardt, R.J.5
-
135
-
-
0027248439
-
Calcium-dependent heparin-like ligands for L-selectin in nonlymphoid endothelial cells
-
Norgard-Sumnicht KE, Varki NM, Varki A. 1993. Calcium-dependent heparin-like ligands for L-selectin in nonlymphoid endothelial cells. Science 261:480-83
-
(1993)
Science
, vol.261
, pp. 480-483
-
-
Norgard-Sumnicht, K.E.1
Varki, N.M.2
Varki, A.3
-
136
-
-
0032519957
-
Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents
-
Koenig A, Norgard-Sumnicht K, Linhardt R, Varki A. 1998. Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents. J. Clin. Investig. 101:877-89
-
(1998)
J. Clin. Investig
, vol.101
, pp. 877-889
-
-
Koenig, A.1
Norgard-Sumnicht, K.2
Linhardt, R.3
Varki, A.4
-
137
-
-
33747162038
-
Structural requirements for heparin/heparan sulfate binding to type v collagen
-
Ricard-Blum S, Beraud M, Raynal N, Farndale RW, Ruggiero F. 2006. Structural requirements for heparin/heparan sulfate binding to type V collagen. J. Biol. Chem. 281:25195-204
-
(2006)
J. Biol. Chem
, vol.281
, pp. 25195-25204
-
-
Ricard-Blum, S.1
Beraud, M.2
Raynal, N.3
Farndale, R.W.4
Ruggiero, F.5
-
138
-
-
0032491615
-
Lysine 58 and histidine 66 at the C-Terminal alpha;-helix of monocyte chemoattractant protein 1 are essential for glycosaminoglycan binding
-
Chakravarty L, Rogers L, Quach T, Breckenridge S, Kolattukudy PE. 1998. Lysine 58 and histidine 66 at the C-Terminal alpha;-helix of monocyte chemoattractant protein 1 are essential for glycosaminoglycan binding. J. Biol. Chem. 273:29641-47
-
(1998)
J. Biol. Chem
, vol.273
, pp. 29641-29647
-
-
Chakravarty, L.1
Rogers, L.2
Quach, T.3
Breckenridge, S.4
Kolattukudy, P.E.5
-
140
-
-
36348962601
-
Structural and functional characterization of the interaction between cyclophilin B and a heparin-derived oligosaccharide
-
Hanoulle X, Melchior A, Sibille N, Parent B, Denys A, et al. 2007. Structural and functional characterization of the interaction between cyclophilin B and a heparin-derived oligosaccharide. J. Biol. Chem. 282:34148-58
-
(2007)
J. Biol. Chem
, vol.282
, pp. 34148-34158
-
-
Hanoulle, X.1
Melchior, A.2
Sibille, N.3
Parent, B.4
Denys, A.5
-
141
-
-
0024584913
-
Molecular modeling of protein-glycosaminoglycan interactions
-
Cardin AD, Weintraub HJ. 1989. Molecular modeling of protein- glycosaminoglycan interactions. Arteriosclerosis 9:21-32
-
(1989)
Arteriosclerosis
, vol.9
, pp. 21-32
-
-
Cardin, A.D.1
Weintraub, H.J.2
-
142
-
-
0026806511
-
Localization and characterization of a heparin binding domain peptide of human vonWillebrand factor
-
SobelM, Soler DF,Kermode JC,HarrisRB. 1992. Localization and characterization of a heparin binding domain peptide of human vonWillebrand factor. J. Biol. Chem. 267:8857-62
-
(1992)
J. Biol. Chem
, vol.267
, pp. 8857-8862
-
-
Sobel, M.1
Soler, D.F.2
Kermode, J.C.3
Harris, R.B.4
-
143
-
-
0027327277
-
Comparative analysis of structurally defined heparin binding sequences reveals a distinct spatial distribution of basic residues
-
Margalit H, Fischer N, Ben-Sasson SA. 1993. Comparative analysis of structurally defined heparin binding sequences reveals a distinct spatial distribution of basic residues. J. Biol. Chem. 268:19228-31
-
(1993)
J. Biol. Chem
, vol.268
, pp. 19228-19231
-
-
Margalit, H.1
Fischer, N.2
Ben-Sasson, S.A.3
-
145
-
-
84859467539
-
Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin
-
Moon AF, Xu Y,Woody SM, Krahn JM, Linhardt RJ, et al. 2012. Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin. Proc.Natl. Acad. Sci. USA109:5265-70
-
(2012)
Proc.Natl. Acad. Sci. USA109
, pp. 5265-5270
-
-
Moon, A.F.1
Xu, Y.2
Woody, S.M.3
Krahn, J.M.4
Linhardt, R.J.5
-
146
-
-
80055084998
-
Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins
-
Xu Y, Masuko S, Takieddin M, Xu H, Liu R, et al. 2011. Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins. Science 334:498-501
-
(2011)
Science
, vol.334
, pp. 498-501
-
-
Xu, Y.1
Masuko, S.2
Takieddin, M.3
Xu, H.4
Liu, R.5
-
147
-
-
84879605819
-
Multi-faceted substrate specificity of heparanase
-
Peterson SB, Liu J. 2013. Multi-faceted substrate specificity of heparanase. Matrix Biol. 32:223-27
-
(2013)
Matrix Biol
, vol.32
, pp. 223-227
-
-
Peterson, S.B.1
Liu, J.2
-
148
-
-
51349149624
-
Surfen, a small molecule antagonist of heparan sulfate
-
Schuksz M, Fuster MM, Brown JR, Crawford BE, Ditto DP, et al. 2008. Surfen, a small molecule antagonist of heparan sulfate. Proc. Natl. Acad. Sci. USA 105:13075-80
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 13075-13080
-
-
Schuksz, M.1
Fuster, M.M.2
Brown, J.R.3
Crawford, B.E.4
Ditto, D.P.5
|