Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

Science

Volumn 274, Issue 5295, 1996, Pages 2079-2082

  Telling, Glenn C ^a   Parchi, Piero ^b   DeArmond, Stephen J ^c   Cortelli, Pietro ^d   Montagna, Pasquale ^d   Gabizon, Ruth ^e   Mastrianni, James ^a   Lugaresi, Elio ^d   Gambetti, Pierluigi ^b   Prusiner, Stanley B ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF BOLOGNA   (Italy)

^e HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ANIMAL CELL; ARTICLE; BIODIVERSITY; CONFORMATIONAL TRANSITION; DEGLYCOSYLATION; FAMILIAL DISEASE; GENE EXPRESSION REGULATION; INSOMNIA; MOUSE; NONHUMAN; POINT MUTATION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN CONFORMATION;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CREUTZFELDT-JAKOB SYNDROME; HUMANS; MICE; MICE, TRANSGENIC; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PRPSC PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 12644272790     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5295.2079     Document Type: Article

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