Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43

Acta Neuropathologica

Volumn 130, Issue 5, 2015, Pages 643-660

  Walker, Adam K ^a   Spiller, Krista J ^a   Ge, Guanghui ^a   Zheng, Allen ^a   Xu, Yan ^a   Zhou, Melissa ^a   Tripathy, Kalyan ^a   Kwong, Linda K ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Amyotrophic lateral sclerosis (ALS); Frontotemporal dementia (FTD); Frontotemporal lobar degeneration (FTLD); Motor neuron; Mouse model; Neurodegeneration; Spinal cord; TDP 43

Indexed keywords

DOXYCYCLINE; NEUROFILAMENT PROTEIN; TAR DNA BINDING PROTEIN; DNA BINDING PROTEIN; TDP-43 PROTEIN, HUMAN;

AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN ATROPHY; CASE REPORT; CELL INCLUSION; CONTROLLED STUDY; CONVALESCENCE; CORTICAL THICKNESS (BRAIN); DOWN REGULATION; FEMALE; FRONTOTEMPORAL DEMENTIA; FUNCTIONAL STATUS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MOTONEURON; MOTOR CORTEX; MOTOR DYSFUNCTION; MOUSE; MUSCLE ATROPHY; MUSCLE DENERVATION; MUSCLE INNERVATION; NEUROMUSCULAR SYNAPSE; NEUROPATHOLOGY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SOMATOSENSORY CORTEX; SPINAL CORD; TDP 43 PROTEINOPATHY; ANIMAL; ATROPHY; C3H MOUSE; C57BL MOUSE; CELL NUCLEUS; CYTOPLASM; DISEASE MODEL; GENETICS; INNERVATION; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION; SKELETAL MUSCLE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ATROPHY; BRAIN; CELL NUCLEUS; CYTOPLASM; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DOXYCYCLINE; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; MALE; MICE, INBRED C3H; MICE, INBRED C57BL; MOVEMENT DISORDERS; MUSCLE, SKELETAL; RANDOM ALLOCATION; RECOVERY OF FUNCTION; SPINAL CORD;

EID: 84945450480     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1460-x     Document Type: Article

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