-
1
-
-
0022550260
-
Defective brain microtubule assembly in Alzheimer's disease
-
Iqbal K., Grundke-Iqbal I., Zaidi T., Defective brain microtubule assembly in Alzheimer's disease The Lancet 1986 2 8504 421 426 (Pubitemid 16047953)
-
(1986)
Lancet
, vol.2
, Issue.8504
, pp. 421-426
-
-
Iqbal, K.1
Grundke-Iqbal, I.2
Zaidi, T.3
-
2
-
-
0024455082
-
Microtubular reorganization and dendritic growth response in Alzheimer's disease
-
Mckee A. C., Kowall N. W., Kosik K. S., Microtubular reorganization and dendritic growth response in Alzheimer's disease Annals of Neurology 1989 26 5 652 659
-
(1989)
Annals of Neurology
, vol.26
, Issue.5
, pp. 652-659
-
-
McKee, A.C.1
Kowall, N.W.2
Kosik, K.S.3
-
3
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
-
DOI 10.1073/pnas.121119298
-
Alonso A. D. C., Zaidi T., Novak M., Grundke-Iqbal I., Iqbal K., Hyperphosphorylation induces self-assembly of into tangles of paired helical filaments/straight filaments Proceedings of the National Academy of Sciences of the United States of America 2001 98 12 6923 6928 (Pubitemid 32538318)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.12
, pp. 6923-6928
-
-
Alonso, A.D.C.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
4
-
-
33745140951
-
Tau phosphorylation and aggregation in Alzheimer's disease pathology
-
DOI 10.1016/j.febslet.2006.02.067, PII S0014579306002705
-
Avila J., Tau phosphorylation and aggregation in Alzheimer's disease pathology FEBS Letters 2006 580 12 2922 2927 (Pubitemid 44250900)
-
(2006)
FEBS Letters
, vol.580
, Issue.12
, pp. 2922-2927
-
-
Avila, J.1
-
6
-
-
0026799198
-
The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease
-
Crowther R. A., Olesen O. F., Jakes R., Goedert M., The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease FEBS Letters 1992 309 2 199 202
-
(1992)
FEBS Letters
, vol.309
, Issue.2
, pp. 199-202
-
-
Crowther, R.A.1
Olesen, O.F.2
Jakes, R.3
Goedert, M.4
-
7
-
-
0035808361
-
Tau filament formation in transgenic mice expressing P301L tau
-
DOI 10.1074/jbc.M006531200
-
Gtz J., Chen F., Barmettler R., Nitsch R. M., Tau filament formation in transgenic mice expressing P301L tau Journal of Biological Chemistry 2001 276 1 529 534 (Pubitemid 32050347)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.1
, pp. 529-534
-
-
Gotz, J.1
Chen, F.2
Barmettler, R.3
Nitsch, R.M.4
-
8
-
-
0034089887
-
Human tau filaments induce microtubule and synapse loss in an in vivo model of neurofibrillary degenerative disease
-
Hall G. F., Chu B., Lee G., Yao J., Human tau filaments induce microtubule and synapse loss in an in vivo model of neurofibrillary degenerative disease Journal of Cell Science 2000 113 8 1373 1387 (Pubitemid 30240556)
-
(2000)
Journal of Cell Science
, vol.113
, Issue.8
, pp. 1373-1387
-
-
Hall, G.F.1
Chu, B.2
Lee, G.3
Yao, J.4
-
9
-
-
0030894830
-
Human tau becomes phosphorylated and forms filamentous deposits when overexpressed in lamprey central neurons in situ
-
DOI 10.1073/pnas.94.9.4733
-
Hall G. F., Yao J., Lee G., Human tau becomes phosphorylated and forms filamentous deposits when overexpressed in lamprey central neurons in situ Proceedings of the National Academy of Sciences of the United States of America 1997 94 9 4733 4738 (Pubitemid 27194312)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.9
, pp. 4733-4738
-
-
Hall, G.F.1
Yao, J.2
Lee, G.3
-
10
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
Ishihara T., Hong M., Zhang B., Nakagawa Y., Lee M. K., Trojanowski J. Q., Lee V. M. Y., Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform Neuron 1999 24 3 751 762
-
(1999)
Neuron
, vol.24
, Issue.3
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
Lee, V.M.Y.7
-
11
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L)tau protein
-
DOI 10.1038/78078
-
Lewis J., McGowan E., Rockwood J., Melrose H., Nacharaju P., Van Slegtenhorst M., Gwinn-Hardy K., Murphy M. P., Baker M., Yu X., Duff K., Hardy J., Corral A., Lin W. L., Yen S. H., Dickson D. W., Davies P., Hutton M., Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein Nature Genetics 2000 25 4 402 405 (Pubitemid 32983430)
-
(2000)
Nature Genetics
, vol.25
, Issue.4
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
Melrose, H.4
Nacharaju, P.5
Van Slegtenhorst, M.6
Gwinn-Hardy, K.7
Murphy, M.P.8
Baker, M.9
Yu, X.10
Duff, K.11
Hardy, J.12
Corral, A.13
Lin, W.-L.14
Yen, S.-H.15
Dickson, D.W.16
Davies, P.17
Hutton, M.18
-
12
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
Wittmann C. W., Wszolek M. F., Shulman J. M., Salvaterra P. M., Lewis J., Hutton M., Feany M. B., Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles Science 2001 293 5530 711 714 (Pubitemid 32728676)
-
(2001)
Science
, vol.293
, Issue.5530
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
14
-
-
0032561415
-
Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly
-
DOI 10.1016/S0014-5793(98)01217-4, PII S0014579398012174
-
Hasegawa M., Smith M. J., Goedert M., Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly FEBS Letters 1998 437 3 207 210 (Pubitemid 28511158)
-
(1998)
FEBS Letters
, vol.437
, Issue.3
, pp. 207-210
-
-
Hasegawa, M.1
Smith, M.J.2
Goedert, M.3
-
15
-
-
0032484089
-
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17
-
Hong M., Zhukareva V., Vogelsberg-Ragaglia V., Wszolek Z., Reed L., Miller B. I., Geschwind D. H., Bird T. D., McKeel D., Coate A., Morris J. C., Wilhelmsen K. C., Schellenberg G. D., Trojanowski J. Q., Lee V. M. Y., Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17 Science 1998 282 5395 1914 1917 (Pubitemid 28555275)
-
(1998)
Science
, vol.282
, Issue.5395
, pp. 1914-1917
-
-
Hong, M.1
Zhukareva, V.2
Vogelsberg-Ragaglia, V.3
Wszolek, Z.4
Reed, L.5
Miller, B.I.6
Geschwind, D.H.7
Bird, T.D.8
McKeel, D.9
Coate, A.10
Morris, J.C.11
Wilhelmsen, K.C.12
Schellenberg, G.D.13
Trojanowski, J.Q.14
Lee, V.M.-Y.15
-
16
-
-
0033011181
-
Accelerated filament formation from tau protein with specific FTDP-17 missense mutations
-
DOI 10.1016/S0014-5793(99)00294-X, PII S001457939900294X
-
Nacharaju P., Lewis J., Easson C., Yen S., Hackett J., Hutton M., Yen S. H., Accelerated filament formation from tau protein with specific FTDP-17 missense mutations FEBS Letters 1999 447 2-3 195 199 (Pubitemid 29146084)
-
(1999)
FEBS Letters
, vol.447
, Issue.2-3
, pp. 195-199
-
-
Nacharaju, P.1
Lewis, J.2
Easson, C.3
Yen, S.4
Hackett, J.5
Hutton, M.6
Yen, S.-H.7
-
17
-
-
0034193290
-
Missense point mutations of tau to segregate with FTDP-17 exhibit site- specific effects on microtubule structure in COS cells: A novel action of R406W mutation
-
DOI 10.1002/(SICI)1097-4547(2000 0501)60:3<380::AID-JNR 13>3.0.CO;2-5
-
Sahara N., Tomiyama T., Mori H., Missense point mutations of tau to segregate with FTDP-17 exhibit site-specific effects on microtubule structure in COS cells: a novel action of R406W mutation Journal of Neuroscience Research 2000 60 3 380 387 (Pubitemid 30253602)
-
(2000)
Journal of Neuroscience Research
, vol.60
, Issue.3
, pp. 380-387
-
-
Sahara, N.1
Tomiyama, T.2
Mori, H.3
-
18
-
-
58849121778
-
Exonic point mutations of human tau enhance its toxicity and cause characteristic changes in neuronal morphology, tau distribution and tau phosphorylation in the lamprey cellular model of tauopathy
-
Lee S., Jung C., Lee G., Hall G. F., Exonic point mutations of human tau enhance its toxicity and cause characteristic changes in neuronal morphology, tau distribution and tau phosphorylation in the lamprey cellular model of tauopathy Journal of Alzheimer's Disease 2009 16 1 99 111
-
(2009)
Journal of Alzheimer's Disease
, vol.16
, Issue.1
, pp. 99-111
-
-
Lee, S.1
Jung, C.2
Lee, G.3
Hall, G.F.4
-
20
-
-
0003374626
-
Tau protein pathology in neurodegenerative diseases
-
DOI 10.1016/S0166-2236(98)01337-X
-
Spillantini M. G., Goedert M., Tau protein pathology in neurodegenerative diseases Trends in Neurosciences 1998 21 10 428 433 (Pubitemid 28449072)
-
(1998)
Trends in Neurosciences
, vol.21
, Issue.10
, pp. 428-433
-
-
Spillantini, M.G.1
Goedert, M.2
-
21
-
-
7944236911
-
The cytoskeleton in neurodegenerative diseases
-
DOI 10.1002/path.1650
-
Cairns N. J., Lee V. M. Y., Trojanowski J. Q., The cytoskeleton in neurodegenerative diseases Journal of Pathology 2004 204 4 438 449 (Pubitemid 39468155)
-
(2004)
Journal of Pathology
, vol.204
, Issue.4
, pp. 438-449
-
-
Cairns, N.J.1
Lee, V.M.-Y.2
Trojanowski, J.Q.3
-
22
-
-
20044381844
-
Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2004.09.019
-
Guillozet-Bongaarts A. L., Garcia-Sierra F., Reynolds M. R., Horowitz P. M., Fu Y., Wang T., Cahill M. E., Bigio E. H., Berry R. W., Binder L. I., Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease Neurobiology of Aging 2005 26 7 1015 1022 (Pubitemid 40312665)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.7
, pp. 1015-1022
-
-
Guillozet-Bongaarts, A.L.1
Garcia-Sierra, F.2
Reynolds, M.R.3
Horowitz, P.M.4
Fu, Y.5
Wang, T.6
Cahill, M.E.7
Bigio, E.H.8
Berry, R.W.9
Binder, L.I.10
-
23
-
-
38549129613
-
The potential for β-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
-
DOI 10.1523/JNEUROSCI.2824-07.2008
-
Mocanu M. M., Nissen A., Eckermann K., Khlistunova I., Biernat J., Drexler D., Petrova O., Schnig K., Bujard H., Mandelkow E., Zhou L., Rune G., Mandelkow E. M., The potential for -structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous tau in inducible mouse models of tauopathy Journal of Neuroscience 2008 28 3 737 748 (Pubitemid 351159036)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.3
, pp. 737-748
-
-
Mocanu, M.-M.1
Nissen, A.2
Eckermann, K.3
Khlistunova, I.4
Biernat, J.5
Drexler, D.6
Petrova, O.7
Schonig, K.8
Bujard, H.9
Mandelkow, E.10
Zhou, L.11
Rune, G.12
Mandelkow, E.-M.13
-
24
-
-
29344434456
-
C-terminal truncation modulates both nucleation and extension phases of τ fibrillization
-
DOI 10.1016/j.febslet.2005.11.077, PII S0014579305014559
-
Yin H., Kuret J., C-terminal truncation modulates both nucleation and extension phases of fibrillization FEBS Letters 2006 580 1 211 215 (Pubitemid 43005338)
-
(2006)
FEBS Letters
, vol.580
, Issue.1
, pp. 211-215
-
-
Yin, H.1
Kuret, J.2
-
25
-
-
33745152289
-
Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo
-
DOI 10.1016/j.febslet.2006.05.029, PII S0014579306006211
-
Zilka N., Filipcik P., Koson P., Fialova L., Skrabana R., Zilkova M., Rolkova G., Kontsekova E., Novak M., Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo FEBS Letters 2006 580 15 3582 3588 (Pubitemid 43902790)
-
(2006)
FEBS Letters
, vol.580
, Issue.15
, pp. 3582-3588
-
-
Zilka, N.1
Filipcik, P.2
Koson, P.3
Fialova, L.4
Skrabana, R.5
Zilkova, M.6
Rolkova, G.7
Kontsekova, E.8
Novak, M.9
-
26
-
-
33947691643
-
Granular tau oligomers as intermediates of tau filaments
-
DOI 10.1021/bi061359o
-
Maeda S., Sahara N., Saito Y., Murayama M., Yoshiike Y., Kim H., Miyasaka T., Murayama S., Ikai A., Takashima A., Granular tau oligomers as intermediates of tau filaments Biochemistry 2007 46 12 3856 3861 (Pubitemid 46493485)
-
(2007)
Biochemistry
, vol.46
, Issue.12
, pp. 3856-3861
-
-
Maeda, S.1
Sahara, N.2
Saito, Y.3
Murayama, M.4
Yoshiike, Y.5
Kim, H.6
Miyasaka, T.7
Murayama, S.8
Ikai, A.9
Takashima, A.10
-
27
-
-
0028785525
-
Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain
-
Brandt R., Léger J., Lee G., Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain Journal of Cell Biology 1995 131 5 1327 1340
-
(1995)
Journal of Cell Biology
, vol.131
, Issue.5
, pp. 1327-1340
-
-
Brandt, R.1
Léger, J.2
Lee, G.3
-
28
-
-
0037465354
-
Tau polymerization: Role of the amino terminus
-
DOI 10.1021/bi0272510
-
Gamblin T. C., Berry R. W., Binder L. I., Tau polymerization: role of the amino terminus Biochemistry 2003 42 7 2252 2257 (Pubitemid 36258700)
-
(2003)
Biochemistry
, vol.42
, Issue.7
, pp. 2252-2257
-
-
Gamblin, T.C.1
Berry, R.W.2
Binder, L.I.3
-
29
-
-
33750380827
-
N-terminal fragments of tau inhibit full-length tau polymerization in vitro
-
DOI 10.1021/bi061325g
-
Horowitz P. M., LaPointe N., Guillozet-Bongaarts A. L., Berry R. W., Binder L. I., N-terminal fragments of tau inhibit full-length tau polymerization in vitro Biochemistry 2006 45 42 12859 12866 (Pubitemid 44630872)
-
(2006)
Biochemistry
, vol.45
, Issue.42
, pp. 12859-12866
-
-
Horowitz, P.M.1
LaPointe, N.2
Guillozet-Bongaarts, A.L.3
Berry, R.W.4
Binder, L.I.5
-
30
-
-
10944244158
-
Cultured cell and transgenic mouse models for tau pathology linked to β-amyloid
-
DOI 10.1016/j.bbadis.2004.08.008, PII S0925443904001516
-
Bloom G. S., Ren K., Glabe C. G., Cultured cell and transgenic mouse models for tau pathology linked to -amyloid Biochimica et Biophysica Acta 2005 1739 2 116 124 (Pubitemid 40018533)
-
(2005)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1739
, Issue.2
, pp. 116-124
-
-
Bloom, G.S.1
Ren, K.2
Glabe, C.G.3
-
31
-
-
33751218015
-
Tau-dependent microtubule disassembly initiated by prefibrillar β-amyloid
-
DOI 10.1083/jcb.200605187
-
King M. E., Kan H. M., Baas P. W., Erisir A., Glabe C. G., Bloom G. S., Tau-dependent microtubule disassembly initiated by prefibrillar -amyloid Journal of Cell Biology 2006 175 4 541 546 (Pubitemid 44790607)
-
(2006)
Journal of Cell Biology
, vol.175
, Issue.4
, pp. 541-546
-
-
King, M.E.1
Kan, H.-M.2
Baas, P.W.3
Erisir, A.4
Glabe, C.G.5
Bloom, G.S.6
-
32
-
-
0742306778
-
Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons
-
DOI 10.1038/sj.cdd.4401314
-
Amadoro G., Serafino A. L., Barbato C., Ciotti M. T., Sacco A., Calissano P., Canu N., Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons Cell Death and Differentiation 2004 11 2 217 230 (Pubitemid 38159646)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.2
, pp. 217-230
-
-
Amadoro, G.1
Serafino, A.L.2
Barbato, C.3
Ciotti, M.T.4
Sacco, A.5
Calissano, P.6
Canu, N.7
-
33
-
-
20044370830
-
The generation of a 17 kDa neurotoxic fragment: An alternative mechanism by which tau mediates β-amyloid-induced neurodegeneration
-
DOI 10.1523/JNEUROSCI.1125-05.2005
-
Park S. Y., Ferreira A., The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates -amyloid-induced neurodegeneration Journal of Neuroscience 2005 25 22 5365 5375 (Pubitemid 40770916)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.22
, pp. 5365-5375
-
-
Park, S.-Y.1
Ferreira, A.2
-
34
-
-
45649083723
-
Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models
-
Corsetti V., Amadoro G., Gentile A., Capsoni S., Ciotti M. T., Cencioni M. T., Atlante A., Canu N., Rohn T. T., Cattaneo A., Calissano P., Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models Molecular and Cellular Neuroscience 2008 38 3 381 392
-
(2008)
Molecular and Cellular Neuroscience
, vol.38
, Issue.3
, pp. 381-392
-
-
Corsetti, V.1
Amadoro, G.2
Gentile, A.3
Capsoni, S.4
Ciotti, M.T.5
Cencioni, M.T.6
Atlante, A.7
Canu, N.8
Rohn, T.T.9
Cattaneo, A.10
Calissano, P.11
-
35
-
-
27444437758
-
Disease-related modifications in tau affect the interaction between Fyn and tau
-
DOI 10.1074/jbc.M505895200
-
Bhaskar K., Yen S. H., Lee G., Disease-related modifications in tau affect the interaction between fyn and tau Journal of Biological Chemistry 2005 280 42 35119 35125 (Pubitemid 41532698)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.42
, pp. 35119-35125
-
-
Bhaskar, K.1
Yen, S.-H.2
Lee, G.3
-
36
-
-
0344505849
-
Tau interacts with src-family non-receptor tyrosine kinases
-
Lee G., Todd Newman S., Gard D. L., Band H., Panchamoorthy G., Tau interacts with src-family non-receptor tyrosine kinases Journal of Cell Science 1998 111 21 3167 3177 (Pubitemid 28532427)
-
(1998)
Journal of Cell Science
, vol.111
, Issue.21
, pp. 3167-3177
-
-
Lee, G.1
Todd Newman, S.2
Gard, D.L.3
Band, H.4
Panchamoorthy, G.5
-
37
-
-
23744482703
-
Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates
-
DOI 10.1016/j.molbrainres.2005.04.015, PII S0169328X05001889
-
Vega I. E., Cui L., Propst J. A., Hutton M. L., Lee G., Yen S. H., Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates Molecular Brain Research 2005 138 2 135 144 (Pubitemid 41138032)
-
(2005)
Molecular Brain Research
, vol.138
, Issue.2
, pp. 135-144
-
-
Vega, I.E.1
Cui, L.2
Propst, J.A.3
Hutton, M.L.4
Lee, G.5
Yen, S.-H.6
-
38
-
-
33947286683
-
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
-
DOI 10.1038/ncb1528, PII NCB1528
-
Fulga T. A., Elson-Schwab I., Khurana V., Steinhilb M. L., Spires T. L., Hyman B. T., Feany M. B., Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo Nature Cell Biology 2007 9 2 139 148 (Pubitemid 46420856)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.2
, pp. 139-148
-
-
Fulga, T.A.1
Elson-Schwab, I.2
Khurana, V.3
Steinhilb, M.L.4
Spires, T.L.5
Hyman, B.T.6
Feany, M.B.7
-
39
-
-
33750553861
-
Tau interacts with golgi membranes and mediates their association with microtubules
-
DOI 10.1002/cm.20157
-
Farah C. A., Perreault S., Liazoghli D., Desjardins M., Anton A., Lauzon M., Paiement J., Leclerc N., Tau interacts with golgi membranes and mediates their association with microtubules Cell Motility and the Cytoskeleton 2006 63 11 710 724 (Pubitemid 44673949)
-
(2006)
Cell Motility and the Cytoskeleton
, vol.63
, Issue.11
, pp. 710-724
-
-
Farah, C.A.1
Perreault, S.2
Liazoghli, D.3
Desjardins, M.4
Anton, A.5
Lauzon, M.6
Paiement, J.7
Leclerc, N.8
-
40
-
-
77954176744
-
Secretion of human tau fragments resembling CSF-tau in Alzheimer's disease is modulated by the presence of the exon 2 insert
-
Kim W., Lee S., Hall G. F., Secretion of human tau fragments resembling CSF-tau in Alzheimer's disease is modulated by the presence of the exon 2 insert FEBS Letters 2010 584 14 3085 3088
-
(2010)
FEBS Letters
, vol.584
, Issue.14
, pp. 3085-3088
-
-
Kim, W.1
Lee, S.2
Hall, G.F.3
-
41
-
-
77049123465
-
Interneuronal transfer of human tau between lamprey central neurons in situ
-
Kim W., Lee S., Jung C., Ahmed A., Lee G., Hall G. F., Interneuronal transfer of human tau between lamprey central neurons in situ Journal of Alzheimer's Disease 2010 19 2 647 664
-
(2010)
Journal of Alzheimer's Disease
, vol.19
, Issue.2
, pp. 647-664
-
-
Kim, W.1
Lee, S.2
Jung, C.3
Ahmed, A.4
Lee, G.5
Hall, G.F.6
-
42
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost B., Jacks R. L., Diamond M. I., Propagation of tau misfolding from the outside to the inside of a cell Journal of Biological Chemistry 2009 284 19 12845 12852
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.19
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
43
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera F., Bolmont T., Crowther R. A., Abramowski D., Frank S., Probst A., Fraser G., Stalder A. K., Beibel M., Staufenbiel M., Jucker M., Goedert M., Tolnay M., Transmission and spreading of tauopathy in transgenic mouse brain Nature Cell Biology 2009 11 7 909 913
-
(2009)
Nature Cell Biology
, vol.11
, Issue.7
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
Jucker, M.11
Goedert, M.12
Tolnay, M.13
-
44
-
-
0024596556
-
Lamprey neurofilaments combine in one subunit the features of each mammalian NF triplet protein but are highly phosphorylated only in large axons
-
Pleasure S. J., Selzer M. E., Lee V. M. Y., Lamprey neurofilaments combine in one subunit the features of each mammalian NF triplet protein but are highly phosphorylated only in large axons Journal of Neuroscience 1989 9 2 698 709 (Pubitemid 19069513)
-
(1989)
Journal of Neuroscience
, vol.9
, Issue.2
, pp. 698-709
-
-
Pleasure, S.J.1
Selzer, M.E.2
Lee, V.M.-Y.3
-
45
-
-
0033841994
-
The single neurofilament subunit of the lamprey forms filaments and regulates axonal caliber and neuronal size in vivo
-
DOI 10.1002/10 97-0169(200 007)46:3<166::AID-CM 2>3.0.CO;2-8
-
Hall G. F., Chu B., Lee S., Liu Y., Yao J., The single neurofilament subunit of the lamprey forms filaments and regulates axonal caliber and neuronal size in vivo Cell Motility and the Cytoskeleton 2000 46 3 166 182 (Pubitemid 30650041)
-
(2000)
Cell Motility and the Cytoskeleton
, vol.46
, Issue.3
, pp. 166-182
-
-
Hall, G.F.1
Chu, B.2
Lee, S.3
Liu, Yu.4
Yao, J.5
-
46
-
-
0024500598
-
Sprouts emerging from the dendrites of axotomized Lamprey central neurons have axonlike ultrastructure
-
Hall G. F., Poulos A., Cohen M. J., Sprouts emerging from the dendrites of axotomized Lamprey central neurons have axonlike ultrastructure Journal of Neuroscience 1989 9 2 588 599 (Pubitemid 19069504)
-
(1989)
Journal of Neuroscience
, vol.9
, Issue.2
, pp. 588-599
-
-
Hall, G.F.1
Poulos, A.2
Cohen, M.J.3
-
47
-
-
0025729415
-
Microtubule destabilization and neurofilament phosphorylation precede dendritic sprouting after close axotomy of lamprey central neurons
-
Hall G. F., Lee V. M. Y., Kosik K. S., Microtubule destabilization and neurofilament phosphorylation precede dendritic sprouting after close axotomy of lamprey central neurons Proceedings of the National Academy of Sciences of the United States of America 1991 88 11 5016 5020 (Pubitemid 21914674)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.11
, pp. 5016-5020
-
-
Hall, G.F.1
Lee, V.M.-Y.2
Kosik, K.S.3
-
48
-
-
0030725450
-
Cytoskeletal changes correlated with the loss of neuronal polarity in axotomized lamprey central neurons
-
DOI 10.1023/A:1018562331003
-
Hall G. F., Yao J., Selzer M. E., Kosik K. S., Cytoskeletal changes correlated with the loss of neuronal polarity in axotomized lamprey central neurons Journal of Neurocytology 1997 26 11 733 753 (Pubitemid 27496246)
-
(1997)
Journal of Neurocytology
, vol.26
, Issue.11
, pp. 733-753
-
-
Hall, G.F.1
Yao, J.2
Selzer, M.E.3
Kosik, K.S.4
-
49
-
-
0028814709
-
Neurofilament sidearm proteolysis is a prominent early effect of axotomy in lamprey giant central neurons
-
Hall G. F., Lee V. M. Y., Neurofilament sidearm proteolysis is a prominent early effect of axotomy in lamprey giant central neurons Journal of Comparative Neurology 1995 353 1 38 49
-
(1995)
Journal of Comparative Neurology
, vol.353
, Issue.1
, pp. 38-49
-
-
Hall, G.F.1
Lee, V.M.Y.2
-
50
-
-
0029921658
-
Neurofilament spacing, phosphorylation, and axon diameter in regenerating and uninjured lamprey axons
-
Pijak D. S., Hall G. F., Tenicki P. J., Boulos A. S., Lurie D. I., Selzer M. E., Neurofilament spacing, phosphorylation, and axon diameter in regenerating and uninjured lamprey axons Journal of Comparative Neurology 1996 368 4 569 581
-
(1996)
Journal of Comparative Neurology
, vol.368
, Issue.4
, pp. 569-581
-
-
Pijak, D.S.1
Hall, G.F.2
Tenicki, P.J.3
Boulos, A.S.4
Lurie, D.I.5
Selzer, M.E.6
-
51
-
-
0029909180
-
PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans
-
Goedert M., Baur C. P., Ahringer J., Jakes R., Hasegawa M., Spillantini M. G., Smith M. J., Hill F., PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans Journal of Cell Science 1996 109 11 2661 2672 (Pubitemid 26388351)
-
(1996)
Journal of Cell Science
, vol.109
, Issue.11
, pp. 2661-2672
-
-
Goedert, M.1
Baur, C.P.2
Ahringer, J.3
Jakes, R.4
Hasegawa, M.5
Spillantini, M.G.6
Smith, M.J.7
Hill, F.8
-
52
-
-
0035139540
-
Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy
-
Hall G. F., Lee V. M. Y., Lee G., Yao J., Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy American Journal of Pathology 2001 158 1 235 246 (Pubitemid 32096489)
-
(2001)
American Journal of Pathology
, vol.158
, Issue.1
, pp. 235-246
-
-
Hall, G.F.1
Lee, V.M.-Y.2
Lee, G.3
Yao, J.4
-
53
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
-
Schneider A., Biernat J., Von Bergen M., Mandelkow E., Mandelkow E. M., Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments Biochemistry 1999 38 12 3549 3558
-
(1999)
Biochemistry
, vol.38
, Issue.12
, pp. 3549-3558
-
-
Schneider, A.1
Biernat, J.2
Von Bergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
54
-
-
70350234910
-
Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules
-
Fischer D., Mukrasch M. D., Biernat J., Bibow S., Blackledge M., Griesinger C., Mandelkow E., Zweckstetter M., Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules Biochemistry 2009 48 42 10047 10055
-
(2009)
Biochemistry
, vol.48
, Issue.42
, pp. 10047-10055
-
-
Fischer, D.1
Mukrasch, M.D.2
Biernat, J.3
Bibow, S.4
Blackledge, M.5
Griesinger, C.6
Mandelkow, E.7
Zweckstetter, M.8
-
55
-
-
0028978701
-
Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau
-
Seubert P., Mawal-Dewan M., Barbour R., Jakes R., Goedert M., Johnson G. V. W., Litersky J. M., Schenk D., Lieberburg I., Trojanowski J. Q., Lee V. M. Y., Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau Journal of Biological Chemistry 1995 270 32 18917 18922
-
(1995)
Journal of Biological Chemistry
, vol.270
, Issue.32
, pp. 18917-18922
-
-
Seubert, P.1
Mawal-Dewan, M.2
Barbour, R.3
Jakes, R.4
Goedert, M.5
Johnson, G.V.W.6
Litersky, J.M.7
Schenk, D.8
Lieberburg, I.9
Trojanowski, J.Q.10
Lee, V.M.Y.11
-
56
-
-
41949126489
-
Targeting green fluorescent protein to dendritic membrane in central neurons
-
Kameda H., Furuta T., Matsuda W., Ohira K., Nakamura K., Hioki H., Kaneko T., Targeting green fluorescent protein to dendritic membrane in central neurons Neuroscience Research 2008 61 1 79 91
-
(2008)
Neuroscience Research
, vol.61
, Issue.1
, pp. 79-91
-
-
Kameda, H.1
Furuta, T.2
Matsuda, W.3
Ohira, K.4
Nakamura, K.5
Hioki, H.6
Kaneko, T.7
-
57
-
-
0032744491
-
Functional roles for fatty acylated amino-terminal domains in subcellular localization
-
McCabe J. B., Berthiaume L. G., Functional roles for fatty acylated amino-terminal domains in subcellular localization Molecular Biology of the Cell 1999 10 11 3771 3786 (Pubitemid 29534024)
-
(1999)
Molecular Biology of the Cell
, vol.10
, Issue.11
, pp. 3771-3786
-
-
McCabe, J.B.1
Berthiaume, L.G.2
-
58
-
-
0345580607
-
Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease
-
Brion J.-P., Tremp G., Octave J.-N., Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease American Journal of Pathology 1999 154 1 255 270 (Pubitemid 29031633)
-
(1999)
American Journal of Pathology
, vol.154
, Issue.1
, pp. 255-270
-
-
Brion, J.-P.1
Trempdagger, G.2
Octavedagger, J.-N.3
-
59
-
-
0028965635
-
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform
-
Gotz J., Probst A., Spillantini M. G., Schafer T., Jakes R., Burki K., Goedert M., Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform The EMBO Journal 1995 14 7 1304 1313
-
(1995)
The EMBO Journal
, vol.14
, Issue.7
, pp. 1304-1313
-
-
Gotz, J.1
Probst, A.2
Spillantini, M.G.3
Schafer, T.4
Jakes, R.5
Burki, K.6
Goedert, M.7
-
60
-
-
0028838142
-
Sorting mechanisms of tau and MAP2 in neurons: Suppressed axonal transit of MAP2 and locally regulated microtubule binding
-
Kanai Y., Hirokawa N., Sorting mechanisms of tau and MAP2 in neurons: suppressed axonal transit of MAP2 and locally regulated microtubule binding Neuron 1995 14 2 421 432
-
(1995)
Neuron
, vol.14
, Issue.2
, pp. 421-432
-
-
Kanai, Y.1
Hirokawa, N.2
-
61
-
-
0027195313
-
Subcellular localization of tau mRNA in differentiating neuronal cell culture: Implications for neuronal polarity
-
DOI 10.1016/0896-6273(93)90165-N
-
Litman P., Barg J., Rindzoonski L., Ginzburg I., Subcellular localization of tau mRNA in differentiating neuronal cell culture: implications for neuronal polarity Neuron 1993 10 4 627 638 (Pubitemid 23127967)
-
(1993)
Neuron
, vol.10
, Issue.4
, pp. 627-638
-
-
Litman, P.1
Barg, J.2
Rindzoonski, L.3
Ginzburg, I.4
-
62
-
-
33847178181
-
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
-
Myers A. J., Pittman A. M., Zhao A. S., Rohrer K., Kaleem M., Marlowe L., Lees A., Leung D., McKeith I. G., Perry R. H., Morris C. M., Trojanowski J. Q., Clark C., Karlawish J., Arnold S., Forman M. S., Van Deerlin V., de Silva R., Hardy J., The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts Neurobiology of Disease 2007 25 3 561 570
-
(2007)
Neurobiology of Disease
, vol.25
, Issue.3
, pp. 561-570
-
-
Myers, A.J.1
Pittman, A.M.2
Zhao, A.S.3
Rohrer, K.4
Kaleem, M.5
Marlowe, L.6
Lees, A.7
Leung, D.8
McKeith, I.G.9
Perry, R.H.10
Morris, C.M.11
Trojanowski, J.Q.12
Clark, C.13
Karlawish, J.14
Arnold, S.15
Forman, M.S.16
Van Deerlin, V.17
De Silva, R.18
Hardy, J.19
-
63
-
-
12344301460
-
Tau interaction with microtubules in vivo
-
DOI 10.1242/jcs.01531
-
Samsonov A., Yu J. Z., Rasenick M., Popov S. V., Tau interaction with microtubules in vivo Journal of Cell Science 2004 117 25 6129 6141 (Pubitemid 40123977)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.25
, pp. 6129-6141
-
-
Samsonov, A.1
Yu, J.-Z.2
Rasenick, M.3
Popov, S.V.4
-
64
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
DOI 10.1126/science.1152993
-
Dixit R., Ross J. L., Goldman Y. E., Holzbaur E. L. F., Differential regulation of dynein and kinesin motor proteins by tau Science 2008 319 5866 1086 1089 (Pubitemid 351300789)
-
(2008)
Science
, vol.319
, Issue.5866
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.F.4
-
65
-
-
76749162221
-
Mixed microtubules steer dynein-driven cargo transport into dendrites
-
Kapitein L. C., Schlager M. A., Kuijpers M., Wulf P. S., van Spronsen M., MacKintosh F. C., Hoogenraad C. C., Mixed microtubules steer dynein-driven cargo transport into dendrites Current Biology 2010 20 4 290 299
-
(2010)
Current Biology
, vol.20
, Issue.4
, pp. 290-299
-
-
Kapitein, L.C.1
Schlager, M.A.2
Kuijpers, M.3
Wulf, P.S.4
Van Spronsen, M.5
MacKintosh, F.C.6
Hoogenraad, C.C.7
-
66
-
-
68949105821
-
Phosphorylated tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease
-
Ittner L. M., Ke Y. D., Gtz J., Phosphorylated tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease Journal of Biological Chemistry 2009 284 31 20909 20916
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.31
, pp. 20909-20916
-
-
Ittner, L.M.1
Ke, Y.D.2
Gtz, J.3
-
67
-
-
65949098412
-
Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects
-
Falzone T. L., Stokin G. B., Lillo C., Rodrigues E. M., Westerman E. L., Williams D. S., Goldstein L. S. B., Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects Journal of Neuroscience 2009 29 18 5758 5767
-
(2009)
Journal of Neuroscience
, vol.29
, Issue.18
, pp. 5758-5767
-
-
Falzone, T.L.1
Stokin, G.B.2
Lillo, C.3
Rodrigues, E.M.4
Westerman, E.L.5
Williams, D.S.6
Goldstein, L.S.B.7
-
68
-
-
0028362458
-
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
-
DOI 10.1007/s004010050124
-
Braak E., Braaak H., Mandelkow E. M., A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads Acta Neuropathologica 1994 87 6 554 567 (Pubitemid 24158408)
-
(1994)
Acta Neuropathologica
, vol.87
, Issue.6
, pp. 554-567
-
-
Braak, E.1
Braaak, H.2
Mandelkow, E.-M.3
-
69
-
-
0024587074
-
Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease
-
DOI 10.1016/0006-8993(89)91396-6
-
Bancher C., Brunner C., Lassmann H., Budka H., Jellinger K., Wiche G., Seitelberger F., Grundke-Iqbal I., Wisniewski H. M., Accumulation of abnormally phosphorylated precedes the formation of neurofibrillary tangles in Alzheimer's disease Brain Research 1989 477 1-2 90 99 (Pubitemid 19026942)
-
(1989)
Brain Research
, vol.477
, Issue.1-2
, pp. 90-99
-
-
Bancher, C.1
Brunner, C.2
Lassmann, H.3
Budka, H.4
Jellinger, K.5
Wiche, G.6
Seitelberger, F.7
Grundke-Iqbal, I.8
Wisniewski, H.M.9
-
70
-
-
58049214009
-
Tau oligomerization: A role for tau aggregation intermediates linked to neurodegeneration
-
Sahara N., Maeda S., Takashima A., Tau oligomerization: a role for tau aggregation intermediates linked to neurodegeneration Current Alzheimer Research 2008 5 6 591 598
-
(2008)
Current Alzheimer Research
, vol.5
, Issue.6
, pp. 591-598
-
-
Sahara, N.1
Maeda, S.2
Takashima, A.3
-
71
-
-
22344438508
-
Medicine: Tau suppression in a neurodegenerative mouse model improves memory function
-
DOI 10.1126/science.1113694
-
Santacruz K., Lewis J., Spires T., Paulson J., Kotilinek L., Ingelsson M., Guimaraes A., DeTure M., Ramsden M., McCowan E., Forster C., Yue M., Orne J., Janus C., Mariash A., Kuskowski M., Hyman B., Hutton M., Ashe K. H., Medicine: tau suppression in a neurodegenerative mouse model improves memory function Science 2005 309 5733 476 481 (Pubitemid 40994688)
-
(2005)
Science
, vol.309
, Issue.5733
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McCowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
72
-
-
0038152836
-
Anionic micelles and vesicles induce tau fibrillization in vitro
-
DOI 10.1074/jbc.M301663200
-
Chirita C. N., Necula M., Kuret J., Anionic micelles and vesicles induce tau fibrillization in vitro Journal of Biological Chemistry 2003 278 28 25644 25650 (Pubitemid 36835318)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.28
, pp. 25644-25650
-
-
Chirita, C.N.1
Necula, M.2
Kuret, J.3
-
73
-
-
33747790300
-
Folding of the Repeat Domain of Tau Upon Binding to Lipid Surfaces
-
DOI 10.1016/j.jmb.2006.07.018, PII S0022283606008709
-
Barré P., Eliezer D., Folding of the repeat domain of tau upon binding to lipid surfaces Journal of Molecular Biology 2006 362 2 312 326 (Pubitemid 44278850)
-
(2006)
Journal of Molecular Biology
, vol.362
, Issue.2
, pp. 312-326
-
-
Barre, P.1
Eliezer, D.2
-
76
-
-
0028220243
-
Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease
-
Cataldo A. M., Hamilton D. J., Nixon R. A., Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease Brain Research 1994 640 1-2 68 80 (Pubitemid 24086532)
-
(1994)
Brain Research
, vol.640
, Issue.1-2
, pp. 68-80
-
-
Cataldo, A.M.1
Hamilton, D.J.2
Nixon, R.A.3
-
77
-
-
41149085729
-
Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
-
DOI 10.1111/j.1460-9568.2008.06084.x
-
Hamano T., Gendron T. F., Causevic E., Yen S. H., Lin W. L., Isidoro C., Deture M., Ko L. W., Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression European Journal of Neuroscience 2008 27 5 1119 1130 (Pubitemid 351432336)
-
(2008)
European Journal of Neuroscience
, vol.27
, Issue.5
, pp. 1119-1130
-
-
Hamano, T.1
Gendron, T.F.2
Causevic, E.3
Yen, S.-H.4
Lin, W.-L.5
Isidoro, C.6
Deture, M.7
Ko, L.-W.8
-
78
-
-
77957340035
-
Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo
-
Khurana V., Elson-Schwab I., Fulga T. A., Sharp K. A., Loewen C. A., Mulkearns E., Tyynel J., Scherzer C. R., Feany M. B., Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo PLoS Genetics 2010 6 7 11
-
(2010)
PLoS Genetics
, vol.6
, Issue.7
, pp. 11
-
-
Khurana, V.1
Elson-Schwab, I.2
Fulga, T.A.3
Sharp, K.A.4
Loewen, C.A.5
Mulkearns, E.6
Tyynel, J.7
Scherzer, C.R.8
Feany, M.B.9
-
79
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
-
Boland B., Kumar A., Lee S., Platt F. M., Wegiel J., Yu W. H., Nixon R. A., Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease Journal of Neuroscience 2008 28 27 6926 6937
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.27
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
80
-
-
77954571538
-
A caspase cleaved form of tau is preferentially degraded through the autophagy pathway
-
Dolan P. J., Johnson G. V. W., A caspase cleaved form of tau is preferentially degraded through the autophagy pathway Journal of Biological Chemistry 2010 285 29 21978 21987
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.29
, pp. 21978-21987
-
-
Dolan, P.J.1
Johnson, G.V.W.2
-
81
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
-
Nixon R. A., Wegiel J., Kumar A., Yu W. H., Peterhoff C., Cataldo A., Cuervo A. M., Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study Journal of Neuropathology and Experimental Neurology 2005 64 2 113 122 (Pubitemid 40349309)
-
(2005)
Journal of Neuropathology and Experimental Neurology
, vol.64
, Issue.2
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
Yu, W.H.4
Peterhoff, C.5
Cataldo, A.6
Cuervo, A.M.7
-
82
-
-
84856707794
-
Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid (CSF) in early Alzheimer's Disease
-
In press
-
Saman S., Kim W., Raya M., Visnick Y., Miro S., Saman S., Jackson B., McKee A. C., Alvarez V. E., Lee N. C., Hall G. F., Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid (CSF) in early Alzheimer's Disease. The Journal of Biological Chemistry. In press
-
The Journal of Biological Chemistry
-
-
Saman, S.1
Kim, W.2
Raya, M.3
Visnick, Y.4
Miro, S.5
Saman, S.6
Jackson, B.7
McKee, A.C.8
Alvarez, V.E.9
Lee, N.C.10
Hall, G.F.11
-
83
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from A 1-42 are potent central nervous system neurotoxins
-
Lambert M. P., Barlow A. K., Chromy B. A., Edwards C., Freed R., Liosatos M., Morgan T. E., Rozovsky I., Trommer B., Viola K. L., Wals P., Zhang C., Finch C. E., Krafft G. A., Klein W. L., Diffusible, nonfibrillar ligands derived from A 1-42 are potent central nervous system neurotoxins Proceedings of the National Academy of Sciences of the United States of America 1998 95 11 6448 6453
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
84
-
-
0037197836
-
Tau is essential to -amyloid-induced neurotoxicity
-
Rapoport M., Dawson H. N., Binder L. I., Vitek M. P., Ferreira A., Tau is essential to -amyloid-induced neurotoxicity Proceedings of the National Academy of Sciences of the United States of America 2002 99 9 6364 6369
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.9
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
85
-
-
12144288564
-
Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease
-
DOI 10.1523/JNEUROSCI.4162-03.2004
-
Lee G., Thangavel R., Sharma V. M., Litersky J. M., Bhaskar K., Fang S. M., Do L. H., Andreadis A., Van Hoesen G., Ksiezak-Reding H., Phosphorylation of tau by fyn: implications for Alzheimer's disease Journal of Neuroscience 2004 24 9 2304 2312 (Pubitemid 38314562)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.9
, pp. 2304-2312
-
-
Lee, G.1
Thangavel, R.2
Sharma, V.M.3
Litersky, J.M.4
Bhaskar, K.5
Fang, S.M.6
Do, L.H.7
Andreadis, A.8
Van Hoesen, G.9
Ksiezak-Reding, H.10
-
86
-
-
13644251548
-
Fyn kinase expression accompanies disease progression in Alzheimer's disease: Implications for its functional role
-
DOI 10.1016/j.neurobiolaging.2004.06.016
-
Ho G. J., Hashimoto M., Adame A., Izu M., Alford M. F., Thal L. J., Hansen L. A., Masliah E., Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role Neurobiology of Aging 2005 26 5 625 635 (Pubitemid 40228754)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.5
, pp. 625-635
-
-
Ho, G.J.1
Hashimoto, M.2
Adame, A.3
Izu, M.4
Alford, M.F.5
Thal, L.J.6
Hansen, L.A.7
Masliah, E.8
-
87
-
-
0036533633
-
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/ζ complex
-
Blanchard N., Lankar D., Faure F., Regnault A., Dumont C., Raposo G., Hivroz C., TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/ complex Journal of Immunology 2002 168 7 3235 3241 (Pubitemid 34250383)
-
(2002)
Journal of Immunology
, vol.168
, Issue.7
, pp. 3235-3241
-
-
Blanchard, N.1
Lankar, D.2
Faure, F.3
Regnault, A.4
Dumont, C.5
Raposo, G.6
Hivroz, C.7
-
89
-
-
34250325547
-
Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes
-
Article E158
-
Fang Y., Wu N., Gan X., Yan W., Morrell J. C., Gould S. J., Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes PLoS Biology 2007 5 6, article e158
-
(2007)
PLoS Biology
, vol.5
, Issue.6
-
-
Fang, Y.1
Wu, N.2
Gan, X.3
Yan, W.4
Morrell, J.C.5
Gould, S.J.6
-
90
-
-
21844468743
-
Unconventional secretory routes: Direct protein export across the plasma membrane of mammalian cells
-
DOI 10.1111/j.1600-0854.2005.00302.x
-
Nickel W., Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells Traffic 2005 6 8 607 614 (Pubitemid 40959689)
-
(2005)
Traffic
, vol.6
, Issue.8
, pp. 607-614
-
-
Nickel, W.1
-
91
-
-
70349987102
-
Tau fragmentation, aggregation and clearance: The dual role of lysosomal processing
-
Wang Y., Martinez-Vicente M., Krger U., Kaushik S., Wong E., Mandelkow E. M., Cuervo A. M., Mandelkow E., Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing Human Molecular Genetics 2009 18 21 4153 4170
-
(2009)
Human Molecular Genetics
, vol.18
, Issue.21
, pp. 4153-4170
-
-
Wang, Y.1
Martinez-Vicente, M.2
Krger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.M.6
Cuervo, A.M.7
Mandelkow, E.8
-
92
-
-
45349096499
-
Cell motility through plasma membrane blebbing
-
DOI 10.1083/jcb.200802081
-
Fackler O. T., Grosse R., Cell motility through plasma membrane blebbing Journal of Cell Biology 2008 181 6 879 884 (Pubitemid 351846821)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.6
, pp. 879-884
-
-
Fackler, O.T.1
Grosse, R.2
-
93
-
-
77955322042
-
Dendritic function of tau mediates amyloid- toxicity in alzheimer's disease mouse models
-
Ittner L. M., Ke Y. D., Delerue F., Bi M., Gladbach A., van Eersel J., Wlfing H., Chieng B. C., Christie M. J., Napier I. A., Eckert A., Staufenbiel M., Hardeman E., Gtz J., Dendritic function of tau mediates amyloid- toxicity in alzheimer's disease mouse models Cell 2010 142 3 387 397
-
(2010)
Cell
, vol.142
, Issue.3
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
Bi, M.4
Gladbach, A.5
Van Eersel, J.6
Wlfing, H.7
Chieng, B.C.8
Christie, M.J.9
Napier, I.A.10
Eckert, A.11
Staufenbiel, M.12
Hardeman, E.13
Gtz, J.14
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