SCOPUS 정보 검색 플랫폼

Science

Volumn 318, Issue 5852, 2007, Pages 930-936

A general model of prion strains and their pathogenicity

(2) Collinge, John a Clarke, Anthony R a

a UNIVERSITY COLLEGE LONDON (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMAL; MOLECULAR ANALYSIS; NUCLEIC ACID; PATHOGENICITY; PRION DISEASE; PROTEIN; TOXIC SUBSTANCE; YEAST;

CONFORMATION; DISEASE TRANSMISSION; KINETICS; MUTATION; NEUROTOXICITY; NONHUMAN; PATHOGENICITY; PRION DISEASE; PRIORITY JOURNAL; REVIEW;

ANIMALS; BRAIN CHEMISTRY; HUMANS; MODELS, BIOLOGICAL; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPC PROTEINS; PRPSC PROTEINS; RECOMBINANT PROTEINS; SPECIES SPECIFICITY;

BOVINAE; FUNGI; MAMMALIA;

EID: 36049020231 PISSN: 00368075 EISSN: 10959203 Source Type: Journal
DOI: 10.1126/science.1138718 Document Type: Review

Times cited : (900)

References (87)

1
- 0014190760
- J. S. Griffith, Nature 215, 1043 (1967).
- (1967) Nature , vol.215 , pp. 1043
- Griffith, J.S.¹

2
- 0020321767
- S. B. Prusiner, Science 216, 136 (1982).
- (1982) Science , vol.216 , pp. 136
- Prusiner, S.B.¹

3
- 0034916581
- J. Collinge, Annu. Rev. Neurosci. 24, 519 (2001).
- (2001) Annu. Rev. Neurosci , vol.24 , pp. 519
- Collinge, J.¹

4
- 0242684410
- S. Mead et al., Science 300, 640 (2003).
- (2003) Science , vol.300 , pp. 640
- Mead, S.¹

5
- 0029831213
- J. Collinge, K. C. L. Sidle, J. Meads, J. Ironside, A. F. Hill, Nature 383, 685 (1996).
- (1996) Nature , vol.383 , pp. 685
- Collinge, J.¹ Sidle, K.C.L.² Meads, J.³ Ironside, J.⁴ Hill, A.F.⁵

6
- 0030820354
- A. F. Hill et al., Nature 389, 448 (1997).
- (1997) Nature , vol.389 , pp. 448
- Hill, A.F.¹

7
- 0030775632
- M. E. Bruce et al., Nature 389, 498 (1997).
- (1997) Nature , vol.389 , pp. 498
- Bruce, M.E.¹

8
- 0033600407
- J. Collinge, Lancet 354, 317 (1999).
- (1999) Lancet , vol.354 , pp. 317
- Collinge, J.¹

9
- 33745440706
- J. Collinge et al., Lancet 367, 2068 (2006).
- (2006) Lancet , vol.367 , pp. 2068
- Collinge, J.¹

10
- 33845227845
- S. J. Wroe et al., Lancet 368, 2061 (2006).
- (2006) Lancet , vol.368 , pp. 2061
- Wroe, S.J.¹

11
- 0024211952
- D. C. Gajdusek, J. Neuroimmunol. 20, 95 (1988).
- (1988) J. Neuroimmunol , vol.20 , pp. 95
- Gajdusek, D.C.¹

12
- 0027270578
- J. H. Come, P. E. Fraser, P. T. J. Lansbury, Proc. Natl. Acad. Sci. U.S.A. 90, 5959 (1993).
- (1993) Proc. Natl. Acad. Sci. U.S.A , vol.90 , pp. 5959
- Come, J.H.¹ Fraser, P.E.² Lansbury, P.T.J.³

13
- 0027195933
- J. T. Jarrett, P. T. J. Lansbury, Cell 73, 1055 (1993).
- (1993) Cell , vol.73 , pp. 1055
- Jarrett, J.T.¹ Lansbury, P.T.J.²

14
- 3442889359
- G. Legname et al., Science 305, 673 (2004).
- (2004) Science , vol.305 , pp. 673
- Legname, G.¹

15
- 0001074386
- C. J. Gajdusek, C. J. Gibbs, M. P. Alpers, Eds, U.S. Government Printing Office, Washington, DC
- I. H. Pattison, in Slow, Latent and Temperate Virus Infections, NINDB Monograph 2, C. J. Gajdusek, C. J. Gibbs, M. P. Alpers, Eds. (U.S. Government Printing Office, Washington, DC, 1965), pp. 249-257.
- (1965) Slow, Latent and Temperate Virus Infections, NINDB Monograph , vol.2 , pp. 249-257
- Pattison, I.H.¹

16
- 0025244011
- S. B. Prusiner et al., Cell 63, 673 (1990).
- (1990) Cell , vol.63 , pp. 673
- Prusiner, S.B.¹

17
- 0025859996
- J. Collinge, M. S. Palmer, A. J. Dryden, Lancet 337, 1441 (1991).
- (1991) Lancet , vol.337 , pp. 1441
- Collinge, J.¹ Palmer, M.S.² Dryden, A.J.³

18
- 0025820942
- M. S. Palmer, A. J. Dryden, J. T. Hughes, J. Collinge, Nature 352, 340 (1991).
- (1991) Nature , vol.352 , pp. 340
- Palmer, M.S.¹ Dryden, A.J.² Hughes, J.T.³ Collinge, J.⁴

19
- 0028782015
- M. Bruce et al., Philos. Trans. R. Soc. London B Biol. Sci. 343, 405 (1994).
- (1994) Philos. Trans. R. Soc. London B Biol. Sci , vol.343 , pp. 405
- Bruce, M.¹

20
- 13344293718
- J. Collinge et al., Nature 378, 779 (1995).
- (1995) Nature , vol.378 , pp. 779
- Collinge, J.¹

21
- 0015550206
- H. Fraser, A. G. Dickinson, J. Comp. Pathol. 83, 29 (1973).
- (1973) J. Comp. Pathol , vol.83 , pp. 29
- Fraser, H.¹ Dickinson, A.G.²

22
- 0026583834
- R. A. Bessen, R. F. Marsh, J. Virol. 66, 2096 (1992).
- (1992) J. Virol , vol.66 , pp. 2096
- Bessen, R.A.¹ Marsh, R.F.²

23
- 0028043661
- R. A. Bessen, R. F. Marsh, J. Virol. 68, 7859 (1994).
- (1994) J. Virol , vol.68 , pp. 7859
- Bessen, R.A.¹ Marsh, R.F.²

24
- 8944259890
- P. Parchi et al., Ann. Neurol. 39, 767 (1996).
- (1996) Ann. Neurol , vol.39 , pp. 767
- Parchi, P.¹

25
- 12644272790
- G. C. Telling et al., Science 274, 2079 (1996).
- (1996) Science , vol.274 , pp. 2079
- Telling, G.C.¹

26
- 0031720905
- J. Safar et al., Nat. Med. 4, 1157 (1998).
- (1998) Nat. Med , vol.4 , pp. 1157
- Safar, J.¹

27
- 0032813254
- T. Kuczius, M. H. Groschup, Mol. Med. 5, 406 (1999).
- (1999) Mol. Med , vol.5 , pp. 406
- Kuczius, T.¹ Groschup, M.H.²

28
- 85044700638
- J. Safar, F. E. Cohen, S. B. Prusiner, Arch. Virol. 16, 227 (2000).
- (2000) Arch. Virol , vol.16 , pp. 227
- Safar, J.¹ Cohen, F.E.² Prusiner, S.B.³

29
- 0033130083
- J. D. F. Wadsworth et al., Nat. Cell Biol. 1, 55 (1999).
- (1999) Nat. Cell Biol , vol.1 , pp. 55
- Wadsworth, J.D.F.¹

30
- 0027956109
- D. A. Kocisko et al., Nature 370, 471 (1994).
- (1994) Nature , vol.370 , pp. 471
- Kocisko, D.A.¹

31
- 0028997297
- R. A. Bessen et al., Nature 375, 698 (1995).
- (1995) Nature , vol.375 , pp. 698
- Bessen, R.A.¹

32
- 17444413067
- J. Castilla, P. Saa, C. Hetz, C. Soto, Cell 121, 195 (2005).
- (2005) Cell , vol.121 , pp. 195
- Castilla, J.¹ Saa, P.² Hetz, C.³ Soto, C.⁴

33
- 23844544189
- A. Khalili-Shirazi et al., J. Gen. Virol. 86, 2635 (2005).
- (2005) J. Gen. Virol , vol.86 , pp. 2635
- Khalili-Shirazi, A.¹

34
- 0028052363
- D. Westaway et al., Cell 76, 117 (1994).
- (1994) Cell , vol.76 , pp. 117
- Westaway, D.¹

35
- 84888732359
- Our unpublished data with aged tga20 mice
- Our unpublished data with aged tga20 mice.

36
- 0029740354
- G. C. Telling et al., Genes Dev. 10, 1736 (1996).
- (1996) Genes Dev , vol.10 , pp. 1736
- Telling, G.C.¹

37
- 22744448690
- K. E. Nazor et al., EMBO J. 24, 2472 (2005).
- (2005) EMBO J , vol.24 , pp. 2472
- Nazor, K.E.¹

38
- 84888650990
- In these experiments, 30 μl of PrP (0.5 mg/ml) was inoculated, which equates to >1014 molecules. An infectious unit of bona fide prion material approximates to 104 to 105 PrP molecules. Therefore, if composed primarily of infectious material, such a synthetic prion inoculum would contain 109 to 1010 infectious units. If dilution of the synthetic prion inoculum 10-fold resulted in no transmissions, this would imply <10 infectious units per undiluted inoculum and therefore that prions composed <1 in 10-8 of the material
- -8 of the material.

39
- 10944228369
- R. B. Wickner et al., Annu. Rev. Genet 38, 681 (2004).
- (2004) Annu. Rev. Genet , vol.38 , pp. 681
- Wickner, R.B.¹

40
- 1642617641
- C. Y. King, R. Diaz-Avalos, Nature 428, 319 (2004).
- (2004) Nature , vol.428 , pp. 319
- King, C.Y.¹ Diaz-Avalos, R.²

41
- 1642633056
- M. Tanaka, P. Chien, N. Naber, R. Cooke, J. S. Weissman, Nature 428, 323 (2004).
- (2004) Nature , vol.428 , pp. 323
- Tanaka, M.¹ Chien, P.² Naber, N.³ Cooke, R.⁴ Weissman, J.S.⁵

42
- 20444474976
- R. Krishnan, S. L. Lindquist, Nature 435, 765 (2005).
- (2005) Nature , vol.435 , pp. 765
- Krishnan, R.¹ Lindquist, S.L.²

43
- 22544450457
- R. Diaz-Avalos, C. Y. King, J. Wall, M. Simon, D. L. Caspar, Proc. Natl. Acad. Sci. U.S.A. 102, 10165 (2005).
- (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 10165
- Diaz-Avalos, R.¹ King, C.Y.² Wall, J.³ Simon, M.⁴ Caspar, D.L.⁵

44
- 17044435107
- M. Tanaka, P. Chien, K. Yonekura, J. S. Weissman, Cell 121, 49 (2005).
- (2005) Cell , vol.121 , pp. 49
- Tanaka, M.¹ Chien, P.² Yonekura, K.³ Weissman, J.S.⁴

45
- 27144451227
- A. Brachmann, U. Baxa, R. B. Wickner, EMBO J. 24, 3082 (2005).
- (2005) EMBO J , vol.24 , pp. 3082
- Brachmann, A.¹ Baxa, U.² Wickner, R.B.³

46
- 0034931126
- K. Wuthrich, R. Riek, Adv. Protein Chem. 57, 55 (2001).
- (2001) Adv. Protein Chem , vol.57 , pp. 55
- Wuthrich, K.¹ Riek, R.²

47
- 33746698975
- M. Tanaka, S. R. Collins, B. H. Toyama, J. S. Weissman, Nature 442, 585 (2006).
- (2006) Nature , vol.442 , pp. 585
- Tanaka, M.¹ Collins, S.R.² Toyama, B.H.³ Weissman, J.S.⁴

48
- 0028252571
- D. M. Taylor et al., Arch. Virol. 139, 313 (1994).
- (1994) Arch. Virol , vol.139 , pp. 313
- Taylor, D.M.¹

49
- 10044224475
- J. D. Wadsworth et al., Science 306, 1793 (2004).
- (2004) Science , vol.306 , pp. 1793
- Wadsworth, J.D.¹

50
- 0027740178
- M. E. Bruce, Br. Med. Bull. 49, 822 (1993).
- (1993) Br. Med. Bull , vol.49 , pp. 822
- Bruce, M.E.¹

51
- 3142615402
- L. L. Hosszu et al., J. Biol. Chem. 279, 28515 (2004).
- (2004) J. Biol. Chem , vol.279 , pp. 28515
- Hosszu, L.L.¹

52
- 18744362997
- E. A. Asante et al., EMBO J. 21, 6358 (2002).
- (2002) EMBO J , vol.21 , pp. 6358
- Asante, E.A.¹

53
- 4043154915
- S. E. Lloyd et al., J. Gen. Virol. 85, 2471 (2004).
- (2004) J. Gen. Virol , vol.85 , pp. 2471
- Lloyd, S.E.¹

54
- 0017866857
- R. H. Kimberlin, C. A. Walker, J. Gen. Virol. 39, 487 (1978).
- (1978) J. Gen. Virol , vol.39 , pp. 487
- Kimberlin, R.H.¹ Walker, C.A.²

55
- 27744459883
- M. Polymenidou et al., Lancet Neurol. 4, 805 (2005).
- (2005) Lancet Neurol , vol.4 , pp. 805
- Polymenidou, M.¹

56
- 30344438495
- H. M. Yull et al., Am. J. Pathol. 168, 151 (2006).
- (2006) Am. J. Pathol , vol.168 , pp. 151
- Yull, H.M.¹

57
- 0031765497
- D. M. Taylor, K. Fernie, I. McConnell, P. J. Steele, Vet. Microbiol. 64, 33 (1998).
- (1998) Vet. Microbiol , vol.64 , pp. 33
- Taylor, D.M.¹ Fernie, K.² McConnell, I.³ Steele, P.J.⁴

58
- 0001770148
- S. B. Prusiner, J. Collinge, J. Powell, B. Anderton, Eds, Horwood, London, chap. 22
- H. Fraser, M. E. Bruce, D. Davies, C. F. Farguhar, P. A. McBride, in Prion Diseases of Humans and Animals, S. B. Prusiner, J. Collinge, J. Powell, B. Anderton, Eds. (Horwood, London, 1992), chap. 22.
- (1992) Prion Diseases of Humans and Animals
- Fraser, H.¹ Bruce, M.E.² Davies, D.³ Farguhar, C.F.⁴ McBride, P.A.⁵

59
- 0032578283
- D. A. Hilton, E. Fathers, P. Edwards, J. W. Ironside, J. Zajicek, Lancet 352, 703 (1998).
- (1998) Lancet , vol.352 , pp. 703
- Hilton, D.A.¹ Fathers, E.² Edwards, P.³ Ironside, J.W.⁴ Zajicek, J.⁵

60
- 0033573778
- A. F. Hill et al., Lancet 353, 183 (1999).
- (1999) Lancet , vol.353 , pp. 183
- Hill, A.F.¹

61
- 0035928432
- J. D. F. Wadsworth et al., Lancet 358, 171 (2001).
- (2001) Lancet , vol.358 , pp. 171
- Wadsworth, J.D.F.¹

62
- 0026600865
- H. Bueler et al., Nature 356, 577 (1992).
- (1992) Nature , vol.356 , pp. 577
- Bueler, H.¹

63
- 0036470471
- G. R. Mallucci et al., EMBO J. 21, 202 (2002).
- (2002) EMBO J , vol.21 , pp. 202
- Mallucci, G.R.¹

64
- 0027319326
- H. Bueler et al., Cell 73, 1339 (1993).
- (1993) Cell , vol.73 , pp. 1339
- Bueler, H.¹

65
- 0028703452
- J. C. Manson, A. R. Clarke, P. A. McBride, I. McConnell, J. Hope, Neurodegeneration 3, 331 (1994).
- (1994) Neurodegeneration , vol.3 , pp. 331
- Manson, J.C.¹ Clarke, A.R.² McBride, P.A.³ McConnell, I.⁴ Hope, J.⁵

66
- 0027483615
- G. Forloni et al., Nature 362, 543 (1993).
- (1993) Nature , vol.362 , pp. 543
- Forloni, G.¹

67
- 0142105406
- C. Hetz, M. Russelakis-Carneiro, K. Maundrell, J. Castilla, C. Soto, EMBO J. 22, 5435 (2003).
- (2003) EMBO J , vol.22 , pp. 5435
- Hetz, C.¹ Russelakis-Carneiro, M.² Maundrell, K.³ Castilla, J.⁴ Soto, C.⁵

68
- 0029160006
- J. Collinge et al., Lancet 346, 569 (1995).
- (1995) Lancet , vol.346 , pp. 569
- Collinge, J.¹

69
- 0026690906
- R. Medori et al., Neurology 42, 669 (1992).
- (1992) Neurology , vol.42 , pp. 669
- Medori, R.¹

70
- 0025681138
- K. K. Hsiao et al., Science 250, 1587 (1990).
- (1990) Science , vol.250 , pp. 1587
- Hsiao, K.K.¹

71
- 0344030333
- C. I. Lasmézas et al., Science 275, 402 (1997).
- (1997) Science , vol.275 , pp. 402
- Lasmézas, C.I.¹

72
- 0028343093
- A. Sailer, H. Bueler, M. Fischer, A. Aguzzi, C. Weissmann, Cell 77, 967 (1994).
- (1994) Cell , vol.77 , pp. 967
- Sailer, A.¹ Bueler, H.² Fischer, M.³ Aguzzi, A.⁴ Weissmann, C.⁵

73
- 0030054010
- S. Brandner et al., Nature 379, 339 (1996).
- (1996) Nature , vol.379 , pp. 339
- Brandner, S.¹

74
- 0242363656
- G. Mallucci et al., Science 302, 871 (2003).
- (2003) Science , vol.302 , pp. 871
- Mallucci, G.¹

75
- 33846538022
- G. R. Mallucci et al., Neuron 53, 325 (2007).
- (2007) Neuron , vol.53 , pp. 325
- Mallucci, G.R.¹

76
- 12144291519
- L. Solforosi et al., Science 313, 1514 (2004).
- (2004) Science , vol.313 , pp. 1514
- Solforosi, L.¹

77
- 0032488777
- R. S. Hegde et al., Science 279, 827 (1998).
- (1998) Science , vol.279 , pp. 827
- Hegde, R.S.¹

78
- 0037195647
- J. Ma, R. Wollmann, S. Lindquist, Science 298, 1781 (2002).
- (2002) Science , vol.298 , pp. 1781
- Ma, J.¹ Wollmann, R.² Lindquist, S.³

79
- 20344394154
- B. Chesebro et al., Science 308, 1435 (2005).
- (2005) Science , vol.308 , pp. 1435
- Chesebro, B.¹

80
- 0034730170
- A. F. Hill et al., Proc. Natl. Acad. Sci. U.S.A. 97, 10248 (2000).
- (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 10248
- Hill, A.F.¹

81
- 0034790796
- R. Race, A. Raines, G. J. Raymond, B. Caughey, B. Chesebro, J. Virol. 75, 10106 (2001).
- (2001) J. Virol , vol.75 , pp. 10106
- Race, R.¹ Raines, A.² Raymond, G.J.³ Caughey, B.⁴ Chesebro, B.⁵

82
- 0344628645
- A. F. Hill, J. Collinge, Trends Microbiol. 11, 578 (2003).
- (2003) Trends Microbiol , vol.11 , pp. 578
- Hill, A.F.¹ Collinge, J.²

83
- 0029863648
- M. Fischer et al., EMBO J. 15, 1255 (1996).
- (1996) EMBO J , vol.15 , pp. 1255
- Fischer, M.¹

84
- 33847662852
- C. Haass, D. J. Selkoe, Nat. Rev. Mol. Cell Biol. 8, 101 (2007).
- (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 101
- Haass, C.¹ Selkoe, D.J.²

85
- 33749020837
- M. Meyer-Luehmann et al., Science 313, 1781 (2006).
- (2006) Science , vol.313 , pp. 1781
- Meyer-Luehmann, M.¹

86
- 84888721310
- L remains hypothetical and cannot yet be assayed directly.
- L remains hypothetical and cannot yet be assayed directly.

87
- 84888710999
- We are grateful to J. Wadsworth for discussion and to R. Young for preparation of figures. J.C. is a director of, and both J.C. and A.R.C. are shareholders in, D-Gen Ltd, a research-based biomedical company that identifies, develops, and exploits proprietary diagnostic and therapeutic targets and technologies for prion-related diseases
- We are grateful to J. Wadsworth for discussion and to R. Young for preparation of figures. J.C. is a director of, and both J.C. and A.R.C. are shareholders in, D-Gen Ltd., a research-based biomedical company that identifies, develops, and exploits proprietary diagnostic and therapeutic targets and technologies for prion-related diseases.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.