A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

Cell

Volumn 162, Issue 5, 2015, Pages 1066-1077

  Patel, Avinash ^a   Lee, Hyun O ^a   Jawerth, Louise ^a,b   Maharana, Shovamayee ^a   Jahnel, Marcus ^a   Hein, Marco Y ^c   Stoynov, Stoyno ^d   Mahamid, Julia ^c   Saha, Shambaditya ^a   Franzmann, Titus M ^a   Pozniakovski, Andrej ^a   Poser, Ina ^a   Maghelli, Nicola ^a   Royer, Loic A ^a   Weigert, Martin ^a   Myers, Eugene W ^a   Grill, Stephan ^a   Drechsel, David ^a   Hyman, Anthony A ^a   Alberti, Simon ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^b MAX PLANCK INSTITUT FÜR PHYSIK KOMPLEXER SYSTEME   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d INSTITUTE OF MOLECULAR BIOLOGY   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN; PROTEIN AGGREGATE; FUS PROTEIN, HUMAN; PRION; RNA BINDING PROTEIN;

AGING; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL AGGREGATION; CELL STRESS; CYTOPLASM; DEGENERATIVE DISEASE; DNA DAMAGE; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN DOMAIN; RISK ASSESSMENT; SOLID; SOLID STATE; CELL NUCLEUS; CHEMISTRY; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PRION; PROTEIN TERTIARY STRUCTURE;

AGING; AMYOTROPHIC LATERAL SCLEROSIS; CELL NUCLEUS; CYTOPLASM; HUMANS; MUTATION; PRIONS; PROTEIN AGGREGATES; PROTEIN STRUCTURE, TERTIARY; RNA-BINDING PROTEIN FUS;

EID: 84940403835     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.07.047     Document Type: Article

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