Small Protease Sensitive Oligomers of PrPSc in Distinct Human Prions Determine Conversion Rate of PrPC

PLoS Pathogens

Volumn 8, Issue 8, 2012, Pages

  Kim, Chae ^a   Haldiman, Tracy ^a   Surewicz, Krystyna ^a   Cohen, Yvonne ^a   Chen, Wei ^a   Blevins, Janis ^a   Sy, Man Sun ^a   Cohen, Mark ^a   Kong, Qingzhong ^a   Telling, Glenn C ^b   Surewicz, Witold K ^a   Safar, Jiri G ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGOMER; PRION PROTEIN;

ARTICLE; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN TISSUE; PRION; PROTEIN CONFORMATION; PROTEIN STABILITY; SPORADIC CREUTZFELDT JAKOB DISEASE; VIRUS REPLICATION; VIRUS STRAIN;

BRAIN; BRAIN CHEMISTRY; CREUTZFELDT-JAKOB SYNDROME; FEMALE; HUMANS; MALE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PRPSC PROTEINS;

MAMMALIAN PRION;

EID: 84866183670     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002835     Document Type: Article

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