Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

Molecular Cell

Volumn 57, Issue 5, 2015, Pages 936-947

  Nott, Timothy J ^a,b   Petsalaki, Evangelia ^a   Farber, Patrick ^c   Jervis, Dylan ^d   Fussner, Eden ^a   Plochowietz, Anne ^b   Craggs, Timothy D ^b   Bazett Jones, David P ^c,e   Pawson, Tony ^a   Forman Kay, Julie D ^c,e   Baldwin, Andrew J ^b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CATION; DDX4 PROTEIN; DOUBLE STRANDED DNA; INTRINSICALLY DISORDERED PROTEIN; NUCLEIC ACID; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; DDX4 PROTEIN, HUMAN; DEAD BOX PROTEIN; DNA; PHOTOPROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL ADHESION; CELL BODY; CELL GRANULE; CELL MEMBRANE; CELL NUCLEUS; CELL ORGANELLE; CELL STRUCTURE; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIC STRENGTH; METHYLATION; PHASE SEPARATION; PHASE TRANSITION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; SOLUBILITY; STATIC ELECTRICITY; TEMPERATURE; CHEMISTRY; CONFOCAL MICROSCOPY; FLUORESCENCE MICROSCOPY; GENETICS; INTRACELLULAR MEMBRANE; METABOLISM; MOLECULAR GENETICS; MUTATION; OSMOLARITY; SEQUENCE HOMOLOGY; TIME LAPSE IMAGING; TRANSITION TEMPERATURE;

AMINO ACID SEQUENCE; CELL NUCLEUS; CYTOPLASMIC GRANULES; DEAD-BOX RNA HELICASES; DNA; HELA CELLS; HUMANS; INTRACELLULAR MEMBRANES; LUMINESCENT PROTEINS; METHYLATION; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; ORGANELLES; OSMOLAR CONCENTRATION; PHASE TRANSITION; SEQUENCE HOMOLOGY, AMINO ACID; STATIC ELECTRICITY; TIME-LAPSE IMAGING; TRANSITION TEMPERATURE;

EID: 84923878820     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.01.013     Document Type: Article

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