Conformational variations in an infectious protein determine prion strain differences

Nature

Volumn 428, Issue 6980, 2004, Pages 323-328

  Tanaka, Motomasa ^a   Chien, Peter ^a,b   Naber, Nariman ^b   Cooke, Roger ^b   Weissman, Jonathan S ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CONFORMATIONS; PARAMAGNETIC RESONANCE; YEAST;

INFECTIOUS MATERIALS; PRION BIOLOGY;

PROTEINS;

AMYLOID; PEPTIDE FRAGMENT; PRION PROTEIN; PROTEIN; RECOMBINANT PROTEIN; SUP35 NM AMYLOID; UNCLASSIFIED DRUG; SACCHAROMYCES CEREVISIAE PROTEIN; SUP35 PROTEIN, S CEREVISIAE;

MEDICINE;

ARTICLE; ELECTRON SPIN RESONANCE; NONHUMAN; PHENOTYPE; PRION; PRION SUP35; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN POLYMORPHISM; STRAIN DIFFERENCE; THERMOSTABILITY; VIRUS PARTICLE; VIRUS STRAIN; VIRUS TRANSMISSION; BIOLOGICAL MODEL; CHEMISTRY; CLASSIFICATION; GENETIC TRANSFORMATION; GENETICS; METABOLISM; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE; TEMPERATURE;

AMYLOID; ELECTRON SPIN RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; PEPTIDE FRAGMENTS; PRIONS; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPECIES SPECIFICITY; TEMPERATURE; TRANSFORMATION, GENETIC;

EID: 1642633056     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02392     Document Type: Article

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