Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils

Science

Volumn 307, Issue 5707, 2005, Pages 262-265

  Petkova, Aneta T ^a   Leapman, Richard D ^b   Guo, Zhihong ^c   Yau, Wai Ming ^a   Mattson, Mark P ^c   Tycko, Robert ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC FORCE MICROSCOPY; CELL CULTURE; ELECTRON MICROSCOPES; IMAGE PROCESSING; MOLECULAR STRUCTURE; MORPHOLOGY; NANOSTRUCTURED MATERIALS; NUCLEAR MAGNETIC RESONANCE; TOXICITY;

ALZHEIMER'S DISEASES; AMYLOID FIBRILS; FIBRIL GROWTH; POLYMORPHISM;

DISEASES;

AMYLOID BETA PROTEIN;

SCIENCE AND TECHNOLOGY;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL STRUCTURE; CYTOTOXICITY; ELECTRON MICROSCOPY; ENZYME POLYMORPHISM; HUMAN; NERVE CELL CULTURE; NUCLEAR MAGNETIC RESONANCE; PRION DISEASE; PRIORITY JOURNAL;

AMINO ACID MOTIFS; AMYLOID BETA-PROTEIN; ANIMALS; CELLS, CULTURED; CHEMISTRY, PHYSICAL; HIPPOCAMPUS; HUMANS; HYDROGEN BONDING; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR STRUCTURE; NEURONS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RATS;

EID: 12244249201     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1105850     Document Type: Article

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