A Network Diffusion Model of Disease Progression in Dementia

Neuron

Volumn 73, Issue 6, 2012, Pages 1204-1215

  Raj, Ashish ^a   Kuceyeski, Amy ^a   Weiner, Michael ^b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALZHEIMER DISEASE; ARTICLE; BOOTSTRAPPING; BRAIN ATROPHY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DEMENTIA; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; DIFFUSION TENSOR IMAGING; DISEASE COURSE; FALSE POSITIVE RESULT; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMAN; MALE; MATHEMATICAL MODEL; MORPHOMETRICS; NERVE CELL NETWORK; NEUROIMAGING; PREDICTIVE VALUE; PREVALENCE; PRIORITY JOURNAL; QUANTITATIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; VOLUMETRY;

ADOLESCENT; ADULT; AGE FACTORS; AGED; ALZHEIMER DISEASE; ATROPHY; BIOPHYSICS; BRAIN; BRAIN MAPPING; CASE-CONTROL STUDIES; DEMENTIA; DISEASE PROGRESSION; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MODELS, NEUROLOGICAL; NEURAL PATHWAYS; PREDICTIVE VALUE OF TESTS; PSYCHIATRIC STATUS RATING SCALES; REPRODUCIBILITY OF RESULTS; ROC CURVE; STATISTICS AS TOPIC; YOUNG ADULT;

EID: 84858648349     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2011.12.040     Document Type: Article

References (63)

1. Acosta-Cabronero Julio, Williams Guy B., Pengas George, Nestor Peter J. Absolute diffusivities define the landscape of white matter degeneration in Alzheimer's disease. Brain. 2010, 133:529-539.
2. Alemán-Gómez, Y., Melie-García, L., and Valdés-Hernandez, P. (2005). IBASPM: toolbox for automatic parcellation of brain structures. Presented at the 12th Annual Meeting of the Organization for Human Brain Mapping, Florence, Italy.
3. Almond D.P., Budd C.J., McCullen N.J. Emergent behaviour in large electrical networks. Approximation Algorithms for Complex Systems 2011, 3-26. Springer, New York. E. Georgoulis, A. Iske, J. Levesley (Eds.).
4. Apostolova L.G., Steiner C.A., Akopyan G.G., Dutton R.A., Hayashi K.M., Toga A.W., Cummings J.L., Thompson P.M. Three-dimensional gray matter atrophy mapping in mild cognitive impairment and mild Alzheimer disease. Arch. Neurol. 2007, 64:1489-1495.
5. Barreda J.L., Zhou H.-X. A solvable model for the diffusion and reaction of neurotransmitters in a synaptic junction. BMC Biophys. 2011, 4:5.
6. Bartzokis G. Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol. Aging 2004, 25:5-18, author reply 49-62.
7. Behrens T.E.J., Berg H.J., Jbabdi S., Rushworth M.F.S., Woolrich M.W. Probabilistic diffusion tractography with multiple fibre orientations: What can we gain?. Neuroimage 2007, 34:144-155.
8. Bhalla U.S. Understanding complex signaling networks through models and metaphors. Prog. Biophys. Mol. Biol. 2002, 81:45-65.
9. Boxer A.L., Miller B.L. Clinical features of frontotemporal dementia. Alzheimer Dis. Assoc. Disord. 2005, 19(Suppl 1):S3-S6.
10. Boxer A.L., Geschwind M.D., Belfor N., Gorno-Tempini M.L., Schauer G.F., Miller B.L., Weiner M.W., Rosen H.J. Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy. Arch. Neurol. 2006, 63:81-86.
11. Braak H., Del Tredici K., Schultz C., Braak E. Vulnerability of select neuronal types to Alzheimer's disease. Ann. N Y Acad. Sci. 2000, 924:53-61.
12. Broe M., Hodges J.R., Schofield E., Shepherd C.E., Kril J.J., Halliday G.M. Staging disease severity in pathologically confirmed cases of frontotemporal dementia. Neurology 2003, 60:1005-1011.
13. Buckner R.L., et al. Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J. Neurosci. 2005, 25:7709-7717.
14. Carlo A.D., et al. Incidence of dementia, Alzheimer's disease, and vascular dementia in Italy. The ILSA Study. J. Am. Geriatr. Soc. 2002, 50:41-48.
15. Curtis C.E., D'Esposito M. Persistent activity in the prefrontal cortex during working memory. Trends Cogn. Sci. 2003, 7:415-423.
16. Du A.-T., Schuff N., Kramer J.H., Rosen H.J., Gorno-Tempini M.L., Rankin K., Miller B.L., Weiner M.W. Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia. Brain. 2007, 130:1159-1166.
17. Englund E., Brun A., Alling C. White matter changes in dementia of Alzheimer's type. Biochemical and neuropathological correlates. Brain 1988, 111:1425-1439.
18. Fischl B., et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 2002, 33:341-355.
19. Forman M.S., et al. Frontotemporal dementia: clinicopathological correlations. Ann. Neurol. 2006, 59:952-962.
20. Frost B., Diamond M.I. Prion-like mechanisms in neurodegenerative diseases. Nat. Rev. Neurosci. 2010, 11:155-159.
21. Frost B., Jacks R.L., Diamond M.I. Propagation of tau misfolding from the outside to the inside of a cell. J. Biol. Chem. 2009, 284:12845-12852.
22. Frost B., Ollesch J., Wille H., Diamond M.I. Conformational diversity of wild-type Tau fibrils specified by templated conformation change. J. Biol. Chem. 2009, 284:3546-3551.
23. Goldberg I.I., Harel M., Malach R. When the brain loses its self: prefrontal inactivation during sensorimotor processing. Neuron 2006, 50:329-339.
24. Gorno-Tempini M.L., Dronkers N.F., Rankin K.P., Ogar J.M., Phengrasamy L., Rosen H.J., Johnson J.K., Weiner M.W., Miller B.L. Cognition and anatomy in three variants of primary progressive aphasia. Ann. Neurol. 2004, 55:335-346.
25. Hardy J. Expression of normal sequence pathogenic proteins for neurodegenerative disease contributes to disease risk: " permissive templating" as a general mechanism underlying neurodegeneration. Biochem. Soc. Trans. 2005, 33:578-581.
26. Harvey R.J. The prevalence and causes of dementia in people under the age of 65 years. J. Neurol. Neurosurg. Psychiatry 2003, 74:1206-1209.
27. He Y., Chen Z., Evans A. Structural insights into aberrant topological patterns of large-scale cortical networks in Alzheimer's disease. J. Neurosci. 2008, 28:4756-4766.
28. Hess C.P., Mukherjee P., Han E.T., Xu D., Vigneron D.B. Q-ball reconstruction of multimodal fiber orientations using the spherical harmonic basis. Magn. Res. Med. 2006, 56:104-117.
29. Iturria-Medina Y., Canales-Rodriguez E.J., Aleman-Gomez Y., Sotero R.C., Melie-Garcia L. Studying the human brain anatomical network via diffusion-weighted MRI and graph theory. Neuroimage 2008, 40:1064-1076.
30. Jellinger K.A., Attems J. Prevalence of dementia disorders in the oldest-old: an autopsy study. Acta Neuropathol. 2010, 119:421-433.
31. Klauschen F., Goldman A., Barra V., Meyer-Lindenberg A., Lundervold A. Evaluation of automated brain MR image segmentation and volumetry methods. Hum. Brain Mapp. 2009, 30:1310-1327.
32. Kobayashi M., Sato T., Sato A., Imamura T. Oldest-old dementia in a Japanese memory clinic. Brain and Nerve 2009, 61:972-978.
33. Kondor R.I., Lafferty J. Diffusion kernels on graphs and other discrete structures. Proc. 19th Intl. Conf. on Machine Learning 2002, 315-322.
34. Kuczynski B., Targan E., Madison C., Weiner M., Zhang Yu, Reed B., Chui H.C., Jagust W. White matter integrity and cortical metabolic associations in aging and dementia. Alzheimers Dement. 2010, 6:54-62.
35. Kukull W.A., Higdon R., Bowen J.D., McCormick W.C., Teri L., Schellenberg G.D., van Belle G., Jolley L., Larson E.B. Dementia and Alzheimer disease incidence: a prospective cohort study. Arch. Neurol. 2002, 59:1737-1746.
36. Lo C.-Y., Wang P.-N., Chou K.-H., Wang J., He Y., Lin C.-P. Diffusion tensor tractography reveals abnormal topological organization in structural cortical networks in Alzheimer's disease. J. Neurosci. 2010, 30:16876-16885.
37. Lomasko T., Lumsden C.J. One-hit stochastic decline in a mechanochemical model of cytoskeleton-induced neuron death III: diffusion pulse death zones. J. Theor. Biol. 2009, 256:104-116.
38. Martinez S., Cortes J., Bullo F. Motion coordination with distributed information. IEEE Contr. Syst. 2007, 27:75-88.
39. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
40. Morrison P.J. Accurate prevalence and uptake of testing for Huntington's disease. Lancet Neurol. 2010, 9:1147.
41. Neary D., Snowden J. Fronto-temporal dementia: nosology, neuropsychology, and neuropathology. Brain Cogn. 1996, 31:176-187.
42. Neary D., Snowden J.S., Gustafson L., Passant U., Stuss D., Black S., Freedman M., Kertesz A., Robert P.H., Albert M., et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998, 51:1546-1554.
43. Palop J.J., Mucke L. Amyloid-β-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat. Neurosci. 2010, 13:812-818.
44. Palop J.J., Chin J., Mucke L. A network dysfunction perspective on neurodegenerative diseases. Nature 2006, 443:768-773.
45. Pereira J.M.S., Williams G.B., Acosta-Cabronero J., Pengas G., Spillantini M.G., Xuereb J.H., Hodges J.R., Nestor P.J. Atrophy patterns in histologic vs clinical groupings of frontotemporal lobar degeneration. Neurology 2009, 72:1653-1660.
46. Plassman B.L., Langa K.M., Fisher G.G., Heeringa S.G., Weir D.R., Ofstedal M.B., Burke J.R., Hurd M.D., Potter G.G., Rodgers W.L., et al. Prevalence of dementia in the United States: the aging, demographics, and memory study. Neuroepidemiology 2007, 29:125-132.
47. Rabinovici G.D., Jagust W.J. Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo. Behav. Neurol. 2009, 21:117-128.
48. Rabinovici G.D., Furst A.J., Alkalay A., Racine C.A., O'Neil P.J., Janabi M., Baker S.L., Agarwal N., Bonasera S.J., Mormino E.C., et al. Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden. Brain 2010, 133:512-528.
49. Raj A., Chen Y. The wiring economy principle: connectivity determines anatomy in the human brain. PLoS ONE 2011, 6:e14832.
50. Ratnavalli E., Brayne C., Dawson K., Hodges J.R. The prevalence of frontotemporal dementia. Neurology 2002, 58:1615-1621.
51. Rosas H.D., Salat D.H., Lee S.Y., Zaleta A.K., Pappu V., Fischl B., Greve D., Hevelone N., Hersch S.M. Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity. Brain 2008, 131:1057-1068.
52. Santos S.F., Pierrot N., Octave J.-N. Network excitability dysfunction in Alzheimer's disease: insights from in vitro and in vivo models. Rev. Neurosci. 2010, 21:153-171.
53. Saxena S., Caroni P. Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration. Neuron 2011, 71:35-48.
54. Seeley W.W., Crawford R., Rascovsky K., Kramer J.H., Weiner M., Miller B.L., Gorno-Tempini M.L. Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia. Arch. Neurol. 2008, 65:249-255.
55. Seeley W.W., Crawford R.K., Zhou J., Miller B.L., Greicius M.D. Neurodegenerative diseases target large-scale human brain networks. Neuron 2009, 62:42-52.
56. Shalizi, C. (2001). Causal architecture, complexity and self-organization in time series and cellular automata. PhD thesis, University of Wisconsin, Madison, WI. (). http://www.cscs.umich.edu/crshalizi/thesis/.
57. Smith S.M., et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004, 23(Suppl 1):S208-S219.
58. Thompson P.M., et al. Dynamics of gray matter loss in Alzheimer's disease. J. Neurosci. 2003, 23:994-1005.
59. Villain N., Desgranges B., Viader F., Sayette V., de la, Mézenge F., Landeau B., Baron J.-C., Eustache F., Chételat G. Relationships between hippocampal atrophy, white matter disruption, and gray matter hypometabolism in Alzheimer's disease. J. Neurosci. 2008, 28:6174-6181.
60. Whitwell J.L., Josephs K.A., Rossor M.N., Stevens J.M., Revesz T., Holton J.L., Al-Sarraj S., Godbolt A.K., Fox N.C., Warren J.D. Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia. Arch. Neurol. 2005, 62:1402-1408.
61. Whitwell J.L., Jack C.R., Senjem M.L., Parisi J.E., Boeve B.F., Knopman D.S., Dickson D.W., Petersen R.C., Josephs K.A. MRI correlates of protein deposition and disease severity in postmortem frontotemporal lobar degeneration. Neurodegener. Dis. 2009, 6:106-117.
62. Wu M., Rosano C., Lopez-Garcia P., Carter C.S., Aizenstein H.J. Optimum template selection for atlas-based segmentation. Neuroimage 2007, 34:1612-1618.
63. Zhou J., et al. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain 2010, 133:1352-1367.