Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils

Neurobiology of Disease

Volumn 73, Issue , 2015, Pages 244-253

  Tsujimura, Atsushi ^a   Taguchi, Katsutoshi ^a   Watanabe, Yoshihisa ^a   Tatebe, Harutsugu ^a   Tokuda, Takahiko ^a   Mizuno, Toshiki ^a   Tanaka, Masaki ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Aggregate formation; Cathepsin B; Fibril; Lysosome; Synuclein

Indexed keywords

ALPHA SYNUCLEIN; CATHEPSIN B; CYAN FLUORESCENT PROTEIN; SMALL INTERFERING RNA; AMYLOID; CATHEPSIN D;

ARTICLE; AUTOPHAGY; CELL AGGREGATION; CELL GROWTH; CELLULAR DISTRIBUTION; CTSB GENE; ENDOCYTOSIS; ENZYME ACTIVITY; GENE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LYSOSOME; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; RNA SEQUENCE; ANTAGONISTS AND INHIBITORS; HUMAN; METABOLISM; PROTEINOSIS;

ALPHA-SYNUCLEIN; AMYLOID; CATHEPSIN B; CATHEPSIN D; HUMANS; LYSOSOMES; PROTEIN AGGREGATION, PATHOLOGICAL;

EID: 84908518328     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.10.011     Document Type: Article

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