-
1
-
-
84877927154
-
Epigenetics: A novel therapeutic approach for the treatment of Alzheimer's disease
-
Adwan L, Zawia NH., 2013. Epigenetics: a novel therapeutic approach for the treatment of Alzheimer's disease. Pharmacol Therapeut 139: 41-50.
-
(2013)
Pharmacol Therapeut
, vol.139
, pp. 41-50
-
-
Adwan, L.1
Zawia, N.H.2
-
2
-
-
84889100159
-
Loss of iron triggers PINK1/Parkin-independent mitophagy
-
Allen GFG, Toth R, James J, Ganley IG., 2013. Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep 14: 1127-1135.
-
(2013)
EMBO Rep
, vol.14
, pp. 1127-1135
-
-
Allen, G.F.G.1
Toth, R.2
James, J.3
Ganley, I.G.4
-
3
-
-
77956190702
-
Optimal micronutrients delay mitochondrial decay and age-associated diseases
-
Ames BN., 2010. Optimal micronutrients delay mitochondrial decay and age-associated diseases. Mech Aging Dev 131: 473-479.
-
(2010)
Mech Aging Dev
, vol.131
, pp. 473-479
-
-
Ames, B.N.1
-
4
-
-
84951573991
-
Why therapies for Alzheimer's disease do not work: Do we have consensus over the path to follow?
-
Amtul Z., 2016. Why therapies for Alzheimer's disease do not work: do we have consensus over the path to follow? Ageing Res Rev 25: 70-84.
-
(2016)
Ageing Res Rev
, vol.25
, pp. 70-84
-
-
Amtul, Z.1
-
5
-
-
84886600387
-
Therapeutics of Alzheimer's disease: Past, present and future
-
Anand R, Gill KD, Mahdi AA., 2014. Therapeutics of Alzheimer's disease: past, present and future. Neuropharmacology 76: 27-50.
-
(2014)
Neuropharmacology
, vol.76
, pp. 27-50
-
-
Anand, R.1
Gill, K.D.2
Mahdi, A.A.3
-
6
-
-
84945474523
-
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
-
Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, Wolozin B, Butovsky O, Kügler S, Ikezu T., 2015. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nat Neurosci 18: 1584-1593.
-
(2015)
Nat Neurosci
, vol.18
, pp. 1584-1593
-
-
Asai, H.1
Ikezu, S.2
Tsunoda, S.3
Medalla, M.4
Luebke, J.5
Haydar, T.6
Wolozin, B.7
Butovsky, O.8
Kügler, S.9
Ikezu, T.10
-
7
-
-
84871005673
-
The pathways of mitophagy for quality control and clearance of mitochondria
-
Ashrafi G, Schwarz TL., 2013. The pathways of mitophagy for quality control and clearance of mitochondria. Nat Cell Death Differ 20: 31-42.
-
(2013)
Nat Cell Death Differ
, vol.20
, pp. 31-42
-
-
Ashrafi, G.1
Schwarz, T.L.2
-
8
-
-
84906861963
-
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
-
Ashrafi G, Schlehe JS, LaVoie MJ, Schwarz TL., 2014. Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J Cell Biol 206: 655-670.
-
(2014)
J Cell Biol
, vol.206
, pp. 655-670
-
-
Ashrafi, G.1
Schlehe, J.S.2
LaVoie, M.J.3
Schwarz, T.L.4
-
9
-
-
84905868301
-
When astrocytes become harmful: Functional and inflammatory responses that contribute to Alzheimer's disease
-
Avila-Muñoz E, Arias C., 2014. When astrocytes become harmful: functional and inflammatory responses that contribute to Alzheimer's disease. Ageing Res Rev 18: 29-40.
-
(2014)
Ageing Res Rev
, vol.18
, pp. 29-40
-
-
Avila-Muñoz, E.1
Arias, C.2
-
10
-
-
84867333272
-
Could decitabine treatment impair memory functions in humans?
-
Aydin B, Hocaoglu N, Gidener S., 2012. Could decitabine treatment impair memory functions in humans? Med Hypothesis 79: 639-641.
-
(2012)
Med Hypothesis
, vol.79
, pp. 639-641
-
-
Aydin, B.1
Hocaoglu, N.2
Gidener, S.3
-
11
-
-
84954289701
-
Case histories Parkinson's disease
-
Barnett R., 2016. Case histories Parkinson's disease. Lancet 387: 217.
-
(2016)
Lancet
, vol.387
, pp. 217
-
-
Barnett, R.1
-
12
-
-
84908217408
-
The role of dietary histone deacetylases (HDACs) inhibitors in health and disease
-
Bassett SA, Barnett MPG., 2014. The role of dietary histone deacetylases (HDACs) inhibitors in health and disease. Nutrients 6: 4273-4301.
-
(2014)
Nutrients
, vol.6
, pp. 4273-4301
-
-
Bassett, S.A.1
Barnett, M.P.G.2
-
14
-
-
0020371958
-
Possible functions of short-chain and medium-chain carnitine acyltransferases
-
Bieber LL, Emaus R, Valkner K, Farrell S., 1982. Possible functions of short-chain and medium-chain carnitine acyltransferases. Fed Proc 41: 2858-2862.
-
(1982)
Fed Proc
, vol.41
, pp. 2858-2862
-
-
Bieber, L.L.1
Emaus, R.2
Valkner, K.3
Farrell, S.4
-
15
-
-
0343092817
-
Enzymatic methods for the preparation of acetyl-CoA and analogs
-
Billhardt U-M, Stein P, Whitesides GM., 1989. Enzymatic methods for the preparation of acetyl-CoA and analogs. Bioorg Chem 17: 1-12.
-
(1989)
Bioorg Chem
, vol.17
, pp. 1-12
-
-
Billhardt, U.-M.1
Stein, P.2
Whitesides, G.M.3
-
16
-
-
84903179483
-
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
-
Bingol B, Tea JS, Phu L, Reichelt M, Bakalarski CE, Song Q, Foreman O, Kirkpatrick DS, Sheng M., 2014. The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. Nature 510: 370-375.
-
(2014)
Nature
, vol.510
, pp. 370-375
-
-
Bingol, B.1
Tea, J.S.2
Phu, L.3
Reichelt, M.4
Bakalarski, C.E.5
Song, Q.6
Foreman, O.7
Kirkpatrick, D.S.8
Sheng, M.9
-
17
-
-
84930206148
-
Comorbidities in neurology: Is adenosine the common link?
-
Boison D, Aronica E., 2015. Comorbidities in neurology: is adenosine the common link? Neuropharmacology 97: 18-34.
-
(2015)
Neuropharmacology
, vol.97
, pp. 18-34
-
-
Boison, D.1
Aronica, E.2
-
18
-
-
71549170836
-
Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications
-
Bolaños JP, Moro MA, Lizasoain I, Almeida A., 2009. Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: therapeutic implications. Adv Drug Deliv Rev 61: 1299-1315.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1299-1315
-
-
Bolaños, J.P.1
Moro, M.A.2
Lizasoain, I.3
Almeida, A.4
-
19
-
-
84863422150
-
Modeling mitochondrial dysfunctions in the brain: From mice to men
-
Breuer ME, Willems PHGM, Russel FGM, Koopman WJH, Smeitink JAM., 2012. Modeling mitochondrial dysfunctions in the brain: from mice to men. J Inherit Metab Dis 35: 193-210.
-
(2012)
J Inherit Metab Dis
, vol.35
, pp. 193-210
-
-
Breuer, M.E.1
Willems, P.H.G.M.2
Russel, F.G.M.3
Koopman, W.J.H.4
Smeitink, J.A.M.5
-
20
-
-
84872675883
-
The role of mitochondrial OXPHOS dysfunction in the development of neurologic diseases
-
Breuer ME, Koopman WJ, Koene S, Nooteboom M, Rodenburg RJ, Willems PH, Smeitink JAM., 2013. The role of mitochondrial OXPHOS dysfunction in the development of neurologic diseases. Neurobiol Dis 51: 27-34.
-
(2013)
Neurobiol Dis
, vol.51
, pp. 27-34
-
-
Breuer, M.E.1
Koopman, W.J.2
Koene, S.3
Nooteboom, M.4
Rodenburg, R.J.5
Willems, P.H.6
Smeitink, J.A.M.7
-
21
-
-
34248525050
-
Targeting lipoic acid to mitochondria: Synthesis and characterization of a triphenylphosphonium-conjugated α-lipoyl derivative
-
Brown SE, Ross MF, Sanjuan-Pla A, Manas A-RB, Smith RAJ, Murphy MP., 2007. Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated α-lipoyl derivative. Free Radic Bio Med 42: 1766-1780.
-
(2007)
Free Radic Bio Med
, vol.42
, pp. 1766-1780
-
-
Brown, S.E.1
Ross, M.F.2
Sanjuan-Pla, A.3
Manas, A.-R.4
Smith, R.A.J.5
Murphy, M.P.6
-
22
-
-
84949725441
-
Glia and alpha-synuclein in neurodegeneration: A complex interaction
-
Brück D, Wenning GK, Stefanova N, Fellner L., 2016. Glia and alpha-synuclein in neurodegeneration: a complex interaction. Neurobiol Dis 85: 262-274.
-
(2016)
Neurobiol Dis
, vol.85
, pp. 262-274
-
-
Brück, D.1
Wenning, G.K.2
Stefanova, N.3
Fellner, L.4
-
23
-
-
71649108692
-
Emerging cognitive enhancing drugs
-
Buccafusco JJ., 2009. Emerging cognitive enhancing drugs. Expert Opin Emerging Drugs 14: 577-589.
-
(2009)
Expert Opin Emerging Drugs
, vol.14
, pp. 577-589
-
-
Buccafusco, J.J.1
-
25
-
-
84949092821
-
Decreased amyloid-β and increased neuronal hyperactivity by immunotherapy in Alzheimer's models
-
Busche MA, Grienberger C, Keskin AD, Song B, Neumann U, Staufenbiel M, Förstl H, Konnerth A., 2015. Decreased amyloid-β and increased neuronal hyperactivity by immunotherapy in Alzheimer's models. Nat Neurosci 18: 1725-1727.
-
(2015)
Nat Neurosci
, vol.18
, pp. 1725-1727
-
-
Busche, M.A.1
Grienberger, C.2
Keskin, A.D.3
Song, B.4
Neumann, U.5
Staufenbiel, M.6
Förstl, H.7
Konnerth, A.8
-
26
-
-
84894437088
-
Environmental exposure and mitochondrial epigenetics: Study design and analytical challenges
-
Byun H-M., Baccarelli AA., 2014. Environmental exposure and mitochondrial epigenetics: study design and analytical challenges. Hum Genet 133: 247-257.
-
(2014)
Hum Genet
, vol.133
, pp. 247-257
-
-
Byun, H.-M.1
Baccarelli, A.A.2
-
27
-
-
84920553828
-
Amyotrophic lateral sclerosis: A focus on disease progression
-
925101
-
Calvo AC, Manzano R, Mendonça DMF, Muñoz MJ, Zaragoza P, Osta R., 2014. Amyotrophic lateral sclerosis: a focus on disease progression. Biomed Res Int 2014: ID 925101.
-
(2014)
Biomed Res Int
, vol.2014
, pp. ID
-
-
Calvo, A.C.1
Manzano, R.2
Mendonça, D.M.F.3
Muñoz, M.J.4
Zaragoza, P.5
Osta, R.6
-
28
-
-
84860229552
-
The epigenetic effects of butyrate: Potential therapeutic implications for clinical practice
-
Canani RB, Di Costanzo M, Leone L., 2012. The epigenetic effects of butyrate: potential therapeutic implications for clinical practice. Clin Epigenet 4: 4.
-
(2012)
Clin Epigenet
, vol.4
, pp. 4
-
-
Canani, R.B.1
Di Costanzo, M.2
Leone, L.3
-
29
-
-
37549020089
-
The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects
-
Carlson DA, Smith AR, Fischer SJ, Young KL, Packer L., 2007. The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects. Altern Med Rev 12: 343-351.
-
(2007)
Altern Med Rev
, vol.12
, pp. 343-351
-
-
Carlson, D.A.1
Smith, A.R.2
Fischer, S.J.3
Young, K.L.4
Packer, L.5
-
30
-
-
84955239862
-
Sulforaphane is anticonvulsant and improves mitochondrial function
-
Carrasco-Pozo C, Tan KN, Borges K., 2015. Sulforaphane is anticonvulsant and improves mitochondrial function. J Neurochem 135: 932-942.
-
(2015)
J Neurochem
, vol.135
, pp. 932-942
-
-
Carrasco-Pozo, C.1
Tan, K.N.2
Borges, K.3
-
31
-
-
84860599622
-
Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities
-
Carvalho C, Cardoso S, Correia SC, Santos RX, Santos MS, Baldeiras I, Oliveira CR, Moreira PI., 2012. Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes 61: 1234-1242.
-
(2012)
Diabetes
, vol.61
, pp. 1234-1242
-
-
Carvalho, C.1
Cardoso, S.2
Correia, S.C.3
Santos, R.X.4
Santos, M.S.5
Baldeiras, I.6
Oliveira, C.R.7
Moreira, P.I.8
-
32
-
-
84924053611
-
Defining pediatric traumatic brain injury using International Classification of Diseases Version 10 Codes: A systematic review
-
Chan V, Thurairajah P, Colantonio A., 2015. Defining pediatric traumatic brain injury using International Classification of Diseases Version 10 Codes: a systematic review. BMC Neurology 15: 7.
-
(2015)
BMC Neurology
, vol.15
, pp. 7
-
-
Chan, V.1
Thurairajah, P.2
Colantonio, A.3
-
34
-
-
84902583416
-
7,8-Dihydroxyflavone ameliorates scopolamine-induced Alzheimer-like pathologic dysfunction
-
Chen C, Li X-H, Zhang S, Tu Y, Wang Y-M, Sun H-T., 2014. 7,8-Dihydroxyflavone ameliorates scopolamine-induced Alzheimer-like pathologic dysfunction. Rejuv Res 17: 249-254.
-
(2014)
Rejuv Res
, vol.17
, pp. 249-254
-
-
Chen, C.1
Li, X.-H.2
Zhang, S.3
Tu, Y.4
Wang, Y.-M.5
Sun, H.-T.6
-
36
-
-
84942549950
-
Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment
-
Cheng L, Doecke JD, Sharples RA, Villemagne VL, Fowler CJ, Rembach A, Martins RN, Rowe CC, Macaulay SL, Masters CL, Hill AF., 2015. Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment. Nat Mol Psychiatry 20: 1188-1196.
-
(2015)
Nat Mol Psychiatry
, vol.20
, pp. 1188-1196
-
-
Cheng, L.1
Doecke, J.D.2
Sharples, R.A.3
Villemagne, V.L.4
Fowler, C.J.5
Rembach, A.6
Martins, R.N.7
Rowe, C.C.8
MacAulay, S.L.9
Masters, C.L.10
Hill, A.F.11
-
38
-
-
84912064761
-
A three-dimensional human neural cell culture model of Alzheimer's disease
-
Choi SH, Kim YH, Hebisch M, Sliwinski C, Lee S, D'Avanzo C, Chen H, Hooli B, Asselin C, Muffat J, et al., 2014. A three-dimensional human neural cell culture model of Alzheimer's disease. Nature 514: 274-278.
-
(2014)
Nature
, vol.514
, pp. 274-278
-
-
Choi, S.H.1
Kim, Y.H.2
Hebisch, M.3
Sliwinski, C.4
Lee, S.5
D'Avanzo, C.6
Chen, H.7
Hooli, B.8
Asselin, C.9
Muffat, J.10
-
39
-
-
84953259927
-
A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease
-
Choong C-J, Sasaki T, Hayakawa H, Yasuda T, Baba K, Hirata Y, Uesato S, Mochizuki H., 2016. A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease. Neurobiol Aging 37: 103-116.
-
(2016)
Neurobiol Aging
, vol.37
, pp. 103-116
-
-
Choong, C.-J.1
Sasaki, T.2
Hayakawa, H.3
Yasuda, T.4
Baba, K.5
Hirata, Y.6
Uesato, S.7
Mochizuki, H.8
-
40
-
-
70350018325
-
Multiple roles of HDAC inhibition in neurodegenerative conditions
-
Chuang D-M, Leng Y, Marinova Z, Kim H-J, Chiu C-T., 2009. Multiple roles of HDAC inhibition in neurodegenerative conditions. Trends Neurosci 32: 591-601.
-
(2009)
Trends Neurosci
, vol.32
, pp. 591-601
-
-
Chuang, D.-M.1
Leng, Y.2
Marinova, Z.3
Kim, H.-J.4
Chiu, C.-T.5
-
41
-
-
84858795033
-
The nuts and bolts of low-level laser (light) therapy
-
Chung H, Dai T, Sharma SK, Huang Y-Y, Carroll JD, Hamblin MR., 2012. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng 40: 516-533.
-
(2012)
Ann Biomed Eng
, vol.40
, pp. 516-533
-
-
Chung, H.1
Dai, T.2
Sharma, S.K.3
Huang, Y.-Y.4
Carroll, J.D.5
Hamblin, M.R.6
-
42
-
-
84945324691
-
Do glia drive synaptic and cognitive impairment in disease?
-
Chung W-S, Welsh CA, Barres BA, Stevens B., 2015. Do glia drive synaptic and cognitive impairment in disease? Nat Neurosci 18: 1539-1545.
-
(2015)
Nat Neurosci
, vol.18
, pp. 1539-1545
-
-
Chung, W.-S.1
Welsh, C.A.2
Barres, B.A.3
Stevens, B.4
-
43
-
-
84906271313
-
The potential of epigenetic therapies in neurodegenerative diseases
-
220
-
Coppedè F., 2014. The potential of epigenetic therapies in neurodegenerative diseases. Front Genet 5: ID 220.
-
(2014)
Front Genet
, vol.5
, pp. ID
-
-
Coppedè, F.1
-
44
-
-
84862777666
-
ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models
-
Cramer PE, Cirrito JR, Wesson DW, Lee CYD, Karlo JC, Zinn AE, Casali BT, Restivo JL, Goebel WD, James MJ, et al., 2012. ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models. Science 335: 1503-1506.
-
(2012)
Science
, vol.335
, pp. 1503-1506
-
-
Cramer, P.E.1
Cirrito, J.R.2
Wesson, D.W.3
Lee, C.Y.D.4
Karlo, J.C.5
Zinn, A.E.6
Casali, B.T.7
Restivo, J.L.8
Goebel, W.D.9
James, M.J.10
-
45
-
-
84923088647
-
Ageing and inflammation - A central role for mitochondria in brain health and disease
-
Currais A., 2015. Ageing and inflammation-a central role for mitochondria in brain health and disease. Ageing Res Rev 21: 30-42.
-
(2015)
Ageing Res Rev
, vol.21
, pp. 30-42
-
-
Currais, A.1
-
46
-
-
84907448267
-
The discovery and development of new potential antioxidant agents for the treatment of neurodegenerative diseases
-
Danta CC, Piplani P., 2014. The discovery and development of new potential antioxidant agents for the treatment of neurodegenerative diseases. Expert Opin Drug Discov 9: 1205-1222.
-
(2014)
Expert Opin Drug Discov
, vol.9
, pp. 1205-1222
-
-
Danta, C.C.1
Piplani, P.2
-
47
-
-
34548456881
-
Dietary histone deacetylase inhibitors: From cells to mice to man
-
Dashwood RH, Ho E., 2007. Dietary histone deacetylase inhibitors: from cells to mice to man. Semin Cancer Biol 17: 363-369.
-
(2007)
Semin Cancer Biol
, vol.17
, pp. 363-369
-
-
Dashwood, R.H.1
Ho, E.2
-
48
-
-
84945493528
-
Evidence of neurodegeneration in obstructive sleep apnea: Relationship between obstructive sleep apnea and cognitive dysfunction in the elderly
-
Daulatzai MA., 2015. Evidence of neurodegeneration in obstructive sleep apnea: relationship between obstructive sleep apnea and cognitive dysfunction in the elderly. J Neurosci Res 93: 1778-1794
-
(2015)
J Neurosci Res
, vol.93
, pp. 1778-1794
-
-
Daulatzai, M.A.1
-
49
-
-
84904011194
-
A mitochondrial expatriate: Nuclear pyruvate dehydrogenase
-
de Boer VCJ, Houten SM., 2014. A mitochondrial expatriate: nuclear pyruvate dehydrogenase. Cell 158: 9-10.
-
(2014)
Cell
, vol.158
, pp. 9-10
-
-
De Boer, V.C.J.1
Houten, S.M.2
-
50
-
-
84919784465
-
Alzheimer's disease: Early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
-
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, et al., 2014. Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nat Neurosci 17: 1156-1163.
-
(2014)
Nat Neurosci
, vol.17
, pp. 1156-1163
-
-
De Jager, P.L.1
Srivastava, G.2
Lunnon, K.3
Burgess, J.4
Schalkwyk, L.C.5
Yu, L.6
Eaton, M.L.7
Keenan, B.T.8
Ernst, J.9
McCabe, C.10
-
51
-
-
84892814749
-
Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits
-
De Vadder F, Kovatcheva-Datchary P, Goncalves D, Vinera J, Zitoun C, Duchampt A, Bäckhed F, Mithieux G., 2014. Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits. Cell 156: 84-96.
-
(2014)
Cell
, vol.156
, pp. 84-96
-
-
De Vadder, F.1
Kovatcheva-Datchary, P.2
Goncalves, D.3
Vinera, J.4
Zitoun, C.5
Duchampt, A.6
Bäckhed, F.7
Mithieux, G.8
-
52
-
-
84859723641
-
A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease
-
Deane R, Singh I, Sagare AP, Bell RD, Ross NT, LaRue B, Love R, Perry S, Paquette N, Deane RJ, et al., 2012. A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest 122: 1377-1392.
-
(2012)
J Clin Invest
, vol.122
, pp. 1377-1392
-
-
Deane, R.1
Singh, I.2
Sagare, A.P.3
Bell, R.D.4
Ross, N.T.5
LaRue, B.6
Love, R.7
Perry, S.8
Paquette, N.9
Deane, R.J.10
-
53
-
-
84949591390
-
Modulation of mitochondrial dysfunction in neurodegenerative diseases via activation of nuclear factor erythroid-2-related factor 2 by food-derived compounds
-
Denzer I, Münch G, Friedland K., 2016. Modulation of mitochondrial dysfunction in neurodegenerative diseases via activation of nuclear factor erythroid-2-related factor 2 by food-derived compounds. Pharmacol Res 103: 80-94.
-
(2016)
Pharmacol Res
, vol.103
, pp. 80-94
-
-
Denzer, I.1
Münch, G.2
Friedland, K.3
-
54
-
-
84863835423
-
Cracking the code: The promise of epigenetics
-
Dhanak D., 2012. Cracking the code: the promise of epigenetics. ACS Med Chem Lett 3: 521-523.
-
(2012)
ACS Med Chem Lett
, vol.3
, pp. 521-523
-
-
Dhanak, D.1
-
55
-
-
84969983910
-
The emerging role of Nrf2 in mitochondrial function
-
Dinkova-Kostova AT, Abramov AY., 2015. The emerging role of Nrf2 in mitochondrial function. Free Radic Bio Med 88: 179-188.
-
(2015)
Free Radic Bio Med
, vol.88
, pp. 179-188
-
-
Dinkova-Kostova, A.T.1
Abramov, A.Y.2
-
57
-
-
84918794600
-
In vitro ischemia decreases histone H4K16 acetylation in neural cells
-
Dmitriev RI, Papkovsky DB., 2015. In vitro ischemia decreases histone H4K16 acetylation in neural cells. FEBS Lett 589: 138-144.
-
(2015)
FEBS Lett
, vol.589
, pp. 138-144
-
-
Dmitriev, R.I.1
Papkovsky, D.B.2
-
58
-
-
84870389262
-
The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation
-
Donohoe DR, Collins LB, Wali A, Bigler R, Sun W, Bultman SJ., 2012. The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation. Mol Cell 48: 612-626.
-
(2012)
Mol Cell
, vol.48
, pp. 612-626
-
-
Donohoe, D.R.1
Collins, L.B.2
Wali, A.3
Bigler, R.4
Sun, W.5
Bultman, S.J.6
-
59
-
-
84942200293
-
Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil
-
Dörsam B, Göder A, Seiwert N, Kaina B, Fahrer J., 2015. Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil. Arch Toxicol 89: 1829-1846.
-
(2015)
Arch Toxicol
, vol.89
, pp. 1829-1846
-
-
Dörsam, B.1
Göder, A.2
Seiwert, N.3
Kaina, B.4
Fahrer, J.5
-
60
-
-
84951748654
-
The disulfide compound α-lipoic acid and its derivatives: A novel class of anticancer agents targeting mitochondria
-
Dörsam B, Fahrer J., 2016. The disulfide compound α-lipoic acid and its derivatives: a novel class of anticancer agents targeting mitochondria. Cancer Lett 371: 12-19.
-
(2016)
Cancer Lett
, vol.371
, pp. 12-19
-
-
Dörsam, B.1
Fahrer, J.2
-
61
-
-
84891815406
-
Comorbidity clusters in autism spectrum disorders: An electronic health record time-series analysis
-
Doshi-Velez F, Ge Y, Kohane I., 2014. Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Pediatrics 133: e54-e63.
-
(2014)
Pediatrics
, vol.133
, pp. e54-e63
-
-
Doshi-Velez, F.1
Ge, Y.2
Kohane, I.3
-
62
-
-
84948716908
-
Disorders of carnitine biosynthesis and transport
-
El-Hattab AW, Scaglia F., 2015. Disorders of carnitine biosynthesis and transport. Mol Genet Metabol 116: 107-112.
-
(2015)
Mol Genet Metabol
, vol.116
, pp. 107-112
-
-
El-Hattab, A.W.1
Scaglia, F.2
-
63
-
-
84877798095
-
Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: New insight into the probiotics for the gut-liver axis
-
Endo H, Niioka M, Kobayashi N, Tanaka M, Watanabe T., 2013. Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis. PLoS One 8: e63388.
-
(2013)
PLoS One
, vol.8
, pp. e63388
-
-
Endo, H.1
Niioka, M.2
Kobayashi, N.3
Tanaka, M.4
Watanabe, T.5
-
64
-
-
84933043202
-
Host microbiota constantly control maturation and function of microglia in the CNS
-
Erny D, Hrabě de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, et al., 2015. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci 18: 965-977.
-
(2015)
Nat Neurosci
, vol.18
, pp. 965-977
-
-
Erny, D.1
Hrabě De Angelis, A.L.2
Jaitin, D.3
Wieghofer, P.4
Staszewski, O.5
David, E.6
Keren-Shaul, H.7
Mahlakoiv, T.8
Jakobshagen, K.9
Buch, T.10
-
65
-
-
84937558111
-
Immune mediators in the brain and peripheral tissues in autism spectrum disorder
-
Estes ML, McAllister AK., 2015. Immune mediators in the brain and peripheral tissues in autism spectrum disorder. Nat Rev Neurosci 16: 469-486.
-
(2015)
Nat Rev Neurosci
, vol.16
, pp. 469-486
-
-
Estes, M.L.1
McAllister, A.K.2
-
66
-
-
84920870609
-
The medical treatment of Parkinson disease from James Parkinson to George Cotzias
-
Fahn S., 2015. The medical treatment of Parkinson disease from James Parkinson to George Cotzias. Mov Disord 30: 4-18.
-
(2015)
Mov Disord
, vol.30
, pp. 4-18
-
-
Fahn, S.1
-
67
-
-
84908265816
-
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
-
Falkenberg KJ, Johnstone RW., 2014. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat Rev Drug Discov 13: 673-691.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 673-691
-
-
Falkenberg, K.J.1
Johnstone, R.W.2
-
68
-
-
77954751786
-
-
Atlanta, GA: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. accessed February 15, 2016
-
Faul M, Xu L, Wald MM, Coronado VG., 2010. Traumatic brain injury in the United States: emergency department visits, hospitalizations and deaths 2002-2006. Atlanta, GA: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. http://www.cdc.gov/TraumaticBrainInjury/severe.html, accessed February 15, 2016.
-
(2010)
Traumatic Brain Injury in the United States: Emergency Department Visits, Hospitalizations and Deaths 2002-2006
-
-
Faul, M.1
Xu, L.2
Wald, M.M.3
Coronado, V.G.4
-
69
-
-
84867578930
-
Mitochondria, oxidative stress and neurodegeneration
-
Federico A, Cardaioli E, Da Pozzo P, Formichi P, Gallus GN, Radi E., 2012. Mitochondria, oxidative stress and neurodegeneration. J Neurol Sci 322: 254-262.
-
(2012)
J Neurol Sci
, vol.322
, pp. 254-262
-
-
Federico, A.1
Cardaioli, E.2
Da Pozzo, P.3
Formichi, P.4
Gallus, G.N.5
Radi, E.6
-
70
-
-
84915783117
-
Discovery of phosphodiesterase-4 inhibitors: Serendipity and rational drug design
-
Feil SC, Holien JK, Morton CJ, Hancock NC, Thompson PE, Parker MW., 2014. Discovery of phosphodiesterase-4 inhibitors: serendipity and rational drug design. Aust J Chem 67: 1780-1785.
-
(2014)
Aust J Chem
, vol.67
, pp. 1780-1785
-
-
Feil, S.C.1
Holien, J.K.2
Morton, C.J.3
Hancock, N.C.4
Thompson, P.E.5
Parker, M.W.6
-
71
-
-
84920771529
-
α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects
-
Fernández-Galilea M, Pérez-Matute P, Prieto-Hontoria PL, Houssier M, Burrell MA, Langin D, Martínez JA, Moreno-Aliaga MJ., 2015. α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects. BBA-Mol Cell Biol Lipid 1851: 273-281.
-
(2015)
BBA-Mol Cell Biol Lipid
, vol.1851
, pp. 273-281
-
-
Fernández-Galilea, M.1
Pérez-Matute, P.2
Prieto-Hontoria, P.L.3
Houssier, M.4
Burrell, M.A.5
Langin, D.6
Martínez, J.A.7
Moreno-Aliaga, M.J.8
-
72
-
-
84929378587
-
Mitochondria-targeted protective compounds in Parkinson's and Alzheimer's diseases
-
ID 408927
-
Fernández-Moriano C, González-Burgos E, Gómez-Serranillos MP., 2015. Mitochondria-targeted protective compounds in Parkinson's and Alzheimer's diseases. Oxid Med Cell Longev 2015:ID 408927 (http://dx.doi.org/10.1155/2015/408927).
-
(2015)
Oxid Med Cell Longev
, vol.2015
-
-
Fernández-Moriano, C.1
González-Burgos, E.2
Gómez-Serranillos, M.P.3
-
73
-
-
84964734987
-
Repetitive mild traumatic brain injury in the developing brain: Effects on long-term functional outcome and neuropathology
-
December 1
-
Fidan E, Lewis J, Kline AE, Garman RH, Alexander H, Cheng JP, Bondi CO, Clark R, Dezfulian C, Kochanek PM, et al., 2015. Repetitive mild traumatic brain injury in the developing brain: effects on long-term functional outcome and neuropathology. J Neurotrauma (December 1, doi: 10.1089/neu.2015.3958).
-
(2015)
J Neurotrauma
-
-
Fidan, E.1
Lewis, J.2
Kline, A.E.3
Garman, R.H.4
Alexander, H.5
Cheng, J.P.6
Bondi, C.O.7
Clark, R.8
Dezfulian, C.9
Kochanek, P.M.10
-
74
-
-
69249152289
-
Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease
-
Fonseca MI, Ager RR, Chu S-H, Yazan O, Sanderson SD, LaFerla FM, Taylor SM, Woodruff TM, Tenner AJ., 2009. Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. J Immunol 183: 1375-1383.
-
(2009)
J Immunol
, vol.183
, pp. 1375-1383
-
-
Fonseca, M.I.1
Ager, R.R.2
Chu, S.-H.3
Yazan, O.4
Sanderson, S.D.5
LaFerla, F.M.6
Taylor, S.M.7
Woodruff, T.M.8
Tenner, A.J.9
-
75
-
-
84898921407
-
The effects of bioactive compounds from plant foods on mitochondrial function: A focus on apoptotic mechanisms
-
Forbes-Hernández TY, Giampieri F, Gasparrini M, Mazzoni L, Quiles JL, Alvarez-Suarez JM, Battino M., 2014. The effects of bioactive compounds from plant foods on mitochondrial function: a focus on apoptotic mechanisms. Food Chem Toxicol 68: 154-182.
-
(2014)
Food Chem Toxicol
, vol.68
, pp. 154-182
-
-
Forbes-Hernández, T.Y.1
Giampieri, F.2
Gasparrini, M.3
Mazzoni, L.4
Quiles, J.L.5
Alvarez-Suarez, J.M.6
Battino, M.7
-
76
-
-
84950150383
-
Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain
-
Forsyth JK, Bachman P, Mathalon DH, Roach BJ, Asarnow RF., 2015. Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain. Proc Natl Acad Sci USA 11: 15331-15336.
-
(2015)
Proc Natl Acad Sci USA
, vol.11
, pp. 15331-15336
-
-
Forsyth, J.K.1
Bachman, P.2
Mathalon, D.H.3
Roach, B.J.4
Asarnow, R.F.5
-
77
-
-
84920426884
-
Autophagy and neurodegeneration
-
Frake RA, Ricketts T, Menzies FM, Rubinsztein DC., 2015. Autophagy and neurodegeneration. J Clin Invest 125: 65-74.
-
(2015)
J Clin Invest
, vol.125
, pp. 65-74
-
-
Frake, R.A.1
Ricketts, T.2
Menzies, F.M.3
Rubinsztein, D.C.4
-
78
-
-
84892600839
-
Mitochondrial form and function
-
Friedman JR, Nunnari J., 2014. Mitochondrial form and function. Nature 505: 335-343.
-
(2014)
Nature
, vol.505
, pp. 335-343
-
-
Friedman, J.R.1
Nunnari, J.2
-
79
-
-
84864928638
-
Tamibarotene: A candidate retinoid drug for Alzheimer's disease
-
Fukasawa H, Nakagomi M, Yamagata N, Katsuki H, Kawahara K, Kitaoka K, Miki T, Shudo K., 2012. Tamibarotene: a candidate retinoid drug for Alzheimer's disease. Biol Pharm Bull 35: 1206-1212.
-
(2012)
Biol Pharm Bull
, vol.35
, pp. 1206-1212
-
-
Fukasawa, H.1
Nakagomi, M.2
Yamagata, N.3
Katsuki, H.4
Kawahara, K.5
Kitaoka, K.6
Miki, T.7
Shudo, K.8
-
80
-
-
84922483772
-
Evidence to support mitochondrial neuroprotection, in severe traumatic brain injury
-
Gajavelli S, Sinha VK, Mazzeo AT, Spurlock MS, Lee SW, Ahmed AI, Yokobori S, Bullock RM., 2015. Evidence to support mitochondrial neuroprotection, in severe traumatic brain injury. J Bioenerg Biomembr 47: 133-148.
-
(2015)
J Bioenerg Biomembr
, vol.47
, pp. 133-148
-
-
Gajavelli, S.1
Sinha, V.K.2
Mazzeo, A.T.3
Spurlock, M.S.4
Lee, S.W.5
Ahmed, A.I.6
Yokobori, S.7
Bullock, R.M.8
-
81
-
-
84863798026
-
Antioxidants for Alzheimer disease: A randomized clinical trial with cerebrospinal fluid biomarker measures
-
Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman JM, Jicha GA, Cotman C, Cottrell B, Montine TJ, Thomas RG, et al., 2012. Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. Arch Neurol 69: 836-841.
-
(2012)
Arch Neurol
, vol.69
, pp. 836-841
-
-
Galasko, D.R.1
Peskind, E.2
Clark, C.M.3
Quinn, J.F.4
Ringman, J.M.5
Jicha, G.A.6
Cotman, C.7
Cottrell, B.8
Montine, T.J.9
Thomas, R.G.10
-
82
-
-
84871878648
-
Alzheimer's disease market: Hope deferred
-
Gerald Z, Ockert W., 2013. Alzheimer's disease market: hope deferred. Nat Rev Drug Discov 12: 19-20.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 19-20
-
-
Gerald, Z.1
Ockert, W.2
-
84
-
-
84954117316
-
BCL-2 Antagonism to target the intrinsic mitochondrial pathway of apoptosis
-
Gibson CJ, Davids MS., 2015. BCL-2 Antagonism to target the intrinsic mitochondrial pathway of apoptosis. Clin Cancer Res 21: 5021-5029.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 5021-5029
-
-
Gibson, C.J.1
Davids, M.S.2
-
85
-
-
84923377359
-
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease
-
Gjoneska E, Pfenning AR, Mathys H, Quon G, Kundaje A, Tsai L-H, Kellis M., 2015. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease. Nature 518: 365-369.
-
(2015)
Nature
, vol.518
, pp. 365-369
-
-
Gjoneska, E.1
Pfenning, A.R.2
Mathys, H.3
Quon, G.4
Kundaje, A.5
Tsai, L.-H.6
Kellis, M.7
-
86
-
-
84953868005
-
Therapeutic strategies for Alzheimer's disease in clinical trials
-
Godyń J, Jończyk J, Panek D, Malawska B., 2016. Therapeutic strategies for Alzheimer's disease in clinical trials. Pharmacol Rep 68: 127-138.
-
(2016)
Pharmacol Rep
, vol.68
, pp. 127-138
-
-
Godyń, J.1
Jończyk, J.2
Panek, D.3
Malawska, B.4
-
87
-
-
84871749760
-
Mitochondrial morphology in mitophagy and macroautophagy
-
Gomes LC, Scorrano L., 2013. Mitochondrial morphology in mitophagy and macroautophagy. BBA-Mol Cell Res 1833: 205-212.
-
(2013)
BBA-Mol Cell Res
, vol.1833
, pp. 205-212
-
-
Gomes, L.C.1
Scorrano, L.2
-
88
-
-
84904774071
-
Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases
-
Gomes MB, Negrato CA., 2014. Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases. Diabetol Metab Syndr 6: 80.
-
(2014)
Diabetol Metab Syndr
, vol.6
, pp. 80
-
-
Gomes, M.B.1
Negrato, C.A.2
-
89
-
-
58149381840
-
Synthesis of carnitine benzyl esters as prodrugs
-
Gong X-W, Li J-P, Wu J-F, Li X, Zhai H-M, Feng B, Wen-Fang Xu W-F, 2008. Synthesis of carnitine benzyl esters as prodrugs. J Chem Res 2008: 327-330.
-
(2008)
J Chem Res
, vol.2008
, pp. 327-330
-
-
Gong, X.-W.1
Li, J.-P.2
Wu, J.-F.3
Li, X.4
Zhai, H.-M.5
Feng, B.6
Wen-Fang Xu, W.-F.7
-
90
-
-
80053351784
-
Lipoic acid - Biological activity and therapeutic potential
-
G orąca A, Huk-Kolega H, Piechota A, Kleniewska P, Ciejka E, Skibska B., 2011. Lipoic acid-biological activity and therapeutic potential. Pharmacol Rep 63: 849-858.
-
(2011)
Pharmacol Rep
, vol.63
, pp. 849-858
-
-
Gorąca, A.1
Huk-Kolega, H.2
Piechota, A.3
Kleniewska, P.4
Ciejka, E.5
Skibska, B.6
-
91
-
-
80051984937
-
Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression
-
Govindarajan N, Agis-Balboa RC, Walter J, Sananbenesi F, Fischer A., 2012. Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression. J Alzheimers Dis 26: 187-197.
-
(2012)
J Alzheimers Dis
, vol.26
, pp. 187-197
-
-
Govindarajan, N.1
Agis-Balboa, R.C.2
Walter, J.3
Sananbenesi, F.4
Fischer, A.5
-
92
-
-
84862777943
-
An epigenetic blockade of cognitive functions in the neurodegenerating brain
-
Gräff J, Rei D, Guan J-S, Wang W-Y, Seo J, Hennig KM, Nieland TJF, Fass DM, Kao PF, Kahn M, et al., 2012. An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature 483: 222-226.
-
(2012)
Nature
, vol.483
, pp. 222-226
-
-
Gräff, J.1
Rei, D.2
Guan, J.-S.3
Wang, W.-Y.4
Seo, J.5
Hennig, K.M.6
Nieland, T.J.F.7
Fass, D.M.8
Kao, P.F.9
Kahn, M.10
-
93
-
-
74549200467
-
Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders?
-
Grayson DR, Kundakovic M, Sharma RP., 2010. Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders? Mol Pharmacol 77: 126-135.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 126-135
-
-
Grayson, D.R.1
Kundakovic, M.2
Sharma, R.P.3
-
94
-
-
84939958312
-
Phosphodiesterase-4 (PDE4) molecular pharmacology and Alzheimer's disease
-
Gurney ME, D'Amato EC, Burgin AB., 2015. Phosphodiesterase-4 (PDE4) molecular pharmacology and Alzheimer's disease. Neurotherapeutics 12: 49-56.
-
(2015)
Neurotherapeutics
, vol.12
, pp. 49-56
-
-
Gurney, M.E.1
D'Amato, E.C.2
Burgin, A.B.3
-
95
-
-
84883788666
-
Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?
-
Harrison IF, Dexter DT., 2013. Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease? Pharmacol Therapeut 140: 34-52.
-
(2013)
Pharmacol Therapeut
, vol.140
, pp. 34-52
-
-
Harrison, I.F.1
Dexter, D.T.2
-
96
-
-
84965190208
-
Movement disorders: Advances in 2015
-
Hattori N., 2016. Movement disorders: advances in 2015. Lancet Neurol 15: 8-9.
-
(2016)
Lancet Neurol
, vol.15
, pp. 8-9
-
-
Hattori, N.1
-
98
-
-
33947544175
-
Modulation of p38 mitogen-activated protein kinase cascade and metalloproteinase activity in diaphragm muscle in response to free radical scavenger administration in dystrophin-deficient mdx mice
-
Hnia K, Hugon G, Rivier F, Masmoudi A, Mercier J, Mornet D., 2007. Modulation of p38 mitogen-activated protein kinase cascade and metalloproteinase activity in diaphragm muscle in response to free radical scavenger administration in dystrophin-deficient mdx mice. Am J Pathol 170: 633-643.
-
(2007)
Am J Pathol
, vol.170
, pp. 633-643
-
-
Hnia, K.1
Hugon, G.2
Rivier, F.3
Masmoudi, A.4
Mercier, J.5
Mornet, D.6
-
99
-
-
77957608608
-
A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation
-
Houten SM, Wanders RJA., 2010. A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation. J Inherit Metab Dis 33: 469-477.
-
(2010)
J Inherit Metab Dis
, vol.33
, pp. 469-477
-
-
Houten, S.M.1
Wanders, R.J.A.2
-
100
-
-
78650736261
-
Cognitive enhancement by drugs in health and disease
-
Husain M, Mehta MA., 2011. Cognitive enhancement by drugs in health and disease. Trends Cogn Sci 15: 28-36.
-
(2011)
Trends Cogn Sci
, vol.15
, pp. 28-36
-
-
Husain, M.1
Mehta, M.A.2
-
102
-
-
84947318181
-
Transition rates between amyloid and neurodegeneration biomarker states and to dementia: A population-based, longitudinal cohort study
-
Jack CR Jr, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, et al., 2016. Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study. Lancet Neurol 15: 56-64.
-
(2016)
Lancet Neurol
, vol.15
, pp. 56-64
-
-
Jack, C.R.1
Therneau, T.M.2
Wiste, H.J.3
Weigand, S.D.4
Knopman, D.S.5
Lowe, V.J.6
Mielke, M.M.7
Vemuri, P.8
Roberts, R.O.9
MacHulda, M.M.10
-
103
-
-
84864700183
-
Epigenetic mechanisms in neurological disease
-
Jakovcevski M, Akbarian S., 2012. Epigenetic mechanisms in neurological disease. Nat Med 18: 1194-1204.
-
(2012)
Nat Med
, vol.18
, pp. 1194-1204
-
-
Jakovcevski, M.1
Akbarian, S.2
-
104
-
-
84861204926
-
PINK1 and Parkin mediated mitophagy at a glance
-
Jin SM, Youle RJ., 2012. PINK1 and Parkin mediated mitophagy at a glance. J Cell Sci 125: 795-799.
-
(2012)
J Cell Sci
, vol.125
, pp. 795-799
-
-
Jin, S.M.1
Youle, R.J.2
-
105
-
-
84969884761
-
Nrf2 - A therapeutic target for the treatment of neurodegenerative diseases
-
Johnson CA, Johnson JA., 2015. Nrf2-a therapeutic target for the treatment of neurodegenerative diseases. Free Radic Bio Med 88: 253-267.
-
(2015)
Free Radic Bio Med
, vol.88
, pp. 253-267
-
-
Johnson, C.A.1
Johnson, J.A.2
-
107
-
-
84922768870
-
Increased Alzheimer's disease-like pathology in the APP/PS1DE9 mouse model lacking Nrf2 through modulation of autophagy
-
Joshi G, Gan KA, Johnson DA, Johnson JA., 2015. Increased Alzheimer's disease-like pathology in the APP/PS1DE9 mouse model lacking Nrf2 through modulation of autophagy. Neurobiol Aging 36: 664-679.
-
(2015)
Neurobiol Aging
, vol.36
, pp. 664-679
-
-
Joshi, G.1
Gan, K.A.2
Johnson, D.A.3
Johnson, J.A.4
-
108
-
-
84947021141
-
Aging causes morphological alterations in astrocytes and microglia in human substantia nigra pars compacta
-
Jyothi HJ, Vidyadhara DJ, Mahadevan A, Philip M, Parmar SK, Manohari SG, Shankar SK, Raju TR, Alladi PA., 2015. Aging causes morphological alterations in astrocytes and microglia in human substantia nigra pars compacta. Neurobiol Aging 36: 3321-3333.
-
(2015)
Neurobiol Aging
, vol.36
, pp. 3321-3333
-
-
Jyothi, H.J.1
Vidyadhara, D.J.2
Mahadevan, A.3
Philip, M.4
Parmar, S.K.5
Manohari, S.G.6
Shankar, S.K.7
Raju, T.R.8
Alladi, P.A.9
-
109
-
-
84941598760
-
Disease-modifying strategies for Parkinson's Disease
-
Kalia LV, Kalia SK, Lang AE., 2015. Disease-modifying strategies for Parkinson's Disease. Mov Disord 30: 1442-1450.
-
(2015)
Mov Disord
, vol.30
, pp. 1442-1450
-
-
Kalia, L.V.1
Kalia, S.K.2
Lang, A.E.3
-
110
-
-
81055129611
-
PINK1 and Parkin flag Miro to direct mitochondrial traffic
-
Kane LA, Youle RJ., 2012. PINK1 and Parkin flag Miro to direct mitochondrial traffic. Cell 147: 721-723.
-
(2012)
Cell
, vol.147
, pp. 721-723
-
-
Kane, L.A.1
Youle, R.J.2
-
111
-
-
84862094662
-
Factors influencing epigenetic mechanisms and related diseases
-
Karagiannis TC, Maulik N., 2012. Factors influencing epigenetic mechanisms and related diseases. Antioxid Redox Sign 17: 192-194.
-
(2012)
Antioxid Redox Sign
, vol.17
, pp. 192-194
-
-
Karagiannis, T.C.1
Maulik, N.2
-
112
-
-
84877921767
-
Potential of chromatin modifying compounds for the treatment of Alzheimer's disease
-
Karagiannis TC, Ververis K., 2012. Potential of chromatin modifying compounds for the treatment of Alzheimer's disease. Pathobiol Aging Age-related Dis 2: 14980.
-
(2012)
Pathobiol Aging Age-related Dis
, vol.2
, pp. 14980
-
-
Karagiannis, T.C.1
Ververis, K.2
-
113
-
-
84907597179
-
A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease
-
Karran E, Hardy J., 2014. A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease. Annal Neurol 76. 185-205.
-
(2014)
Annal Neurol
, vol.76
, pp. 185-205
-
-
Karran, E.1
Hardy, J.2
-
114
-
-
84925940926
-
PINK1 and Parkin - Mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
-
Kazlauskaite A, Muqit MMK., 2015. PINK1 and Parkin-mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease. FEBS J 282: 215-223.
-
(2015)
FEBS J
, vol.282
, pp. 215-223
-
-
Kazlauskaite, A.1
Muqit, M.M.K.2
-
115
-
-
84864283631
-
Age and gender dependent bioavailability of R- and R,S- α-lipoic acid: A pilot study
-
Keith DJ, Butler JA, Bemer B, Dixon B, Johnson S, Garrard M, Sudakin DL, Christensen JM, Pereira C, Hagen TM., 2012. Age and gender dependent bioavailability of R- and R,S- α-lipoic acid: a pilot study. Pharmacol Res 66: 199-206.
-
(2012)
Pharmacol Res
, vol.66
, pp. 199-206
-
-
Keith, D.J.1
Butler, J.A.2
Bemer, B.3
Dixon, B.4
Johnson, S.5
Garrard, M.6
Sudakin, D.L.7
Christensen, J.M.8
Pereira, C.9
Hagen, T.M.10
-
116
-
-
84925500623
-
A mitochondrial bioenergetic basis of depression
-
Klinedinst NJ, Regenold WT., 2015. A mitochondrial bioenergetic basis of depression. J Bioenerg Biomembr 47: 155-171.
-
(2015)
J Bioenerg Biomembr
, vol.47
, pp. 155-171
-
-
Klinedinst, N.J.1
Regenold, W.T.2
-
117
-
-
0345687134
-
Der abbau aromatischer fettsäuren im tierkörper (The degradation of aromatic fatty acids in the animal body)
-
Knoop F., 1904. Der abbau aromatischer fettsäuren im tierkörper (The degradation of aromatic fatty acids in the animal body). Beitr Chem Physiol Pathol 6: 150-162.
-
(1904)
Beitr Chem Physiol Pathol
, vol.6
, pp. 150-162
-
-
Knoop, F.1
-
118
-
-
84964564795
-
Traumatic brain injury research highlights in 2015
-
Kochanek PM, Clark RSB., 2016. Traumatic brain injury research highlights in 2015. Lancet Neurol 15: 13-15.
-
(2016)
Lancet Neurol
, vol.15
, pp. 13-15
-
-
Kochanek, P.M.1
Clark, R.S.B.2
-
119
-
-
84947918250
-
Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model
-
Kratsman N, Getselter D, Evan Elliott E., 2016. Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. Neuropharmacology 102: 136-145.
-
(2016)
Neuropharmacology
, vol.102
, pp. 136-145
-
-
Kratsman, N.1
Getselter, D.2
Evan Elliott, E.3
-
120
-
-
0036217547
-
Differential effects of short-chain fatty acids on head and neck squamous carcinoma cells
-
Krishna S, Brown N, Faller DV, Spanjaard RA., 2002. Differential effects of short-chain fatty acids on head and neck squamous carcinoma cells. Laryngoscope 112: 645-650.
-
(2002)
Laryngoscope
, vol.112
, pp. 645-650
-
-
Krishna, S.1
Brown, N.2
Faller, D.V.3
Spanjaard, R.A.4
-
121
-
-
84920400982
-
Autophagy: A druggable process that is deregulated in aging and human disease
-
Kroemer G., 2015. Autophagy: a druggable process that is deregulated in aging and human disease. J Clin Invest 125: 1-4.
-
(2015)
J Clin Invest
, vol.125
, pp. 1-4
-
-
Kroemer, G.1
-
122
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, et al., 2015. Integrative analysis of 111 reference human epigenomes. Nature 518: 317-330.
-
(2015)
Nature
, vol.518
, pp. 317-330
-
-
Kundaje, A.1
Meuleman, W.2
Ernst, J.3
Bilenky, M.4
Yen, A.5
Heravi-Moussavi, A.6
Kheradpour, P.7
Zhang, Z.8
Wang, J.9
Ziller, M.J.10
-
123
-
-
84864693858
-
Preclinical success against Alzheimer's disease with an old drug
-
LaFerla FM., 2012. Preclinical success against Alzheimer's disease with an old drug. N Engl J Med 367: 570-572.
-
(2012)
N Engl J Med
, vol.367
, pp. 570-572
-
-
LaFerla, F.M.1
-
124
-
-
84949533451
-
NF-κB pathway controls mitochondrial dynamics
-
Laforge M, Rodrigues V, Silvestre R, Gautier C, Weil R, Corti O, Estaquier J., 2016. NF-κB pathway controls mitochondrial dynamics. Nat Cell Death Differ 23: 89-98.
-
(2016)
Nat Cell Death Differ
, vol.23
, pp. 89-98
-
-
Laforge, M.1
Rodrigues, V.2
Silvestre, R.3
Gautier, C.4
Weil, R.5
Corti, O.6
Estaquier, J.7
-
125
-
-
84941739003
-
The role of mitochondrial dysfunction in age-related diseases
-
Lane RK, Hilsabeck T, Rea SL., 2015. The role of mitochondrial dysfunction in age-related diseases. BBA-Bioenergetics 1847: 1387-1400.
-
(2015)
BBA-Bioenergetics
, vol.1847
, pp. 1387-1400
-
-
Lane, R.K.1
Hilsabeck, T.2
Rea, S.L.3
-
127
-
-
84857032953
-
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
-
Lazarou M, Jin SM, Kane LA, Youle RJ., 2012. Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell 22: 230-233.
-
(2012)
Dev Cell
, vol.22
, pp. 230-233
-
-
Lazarou, M.1
Jin, S.M.2
Kane, L.A.3
Youle, R.J.4
-
128
-
-
84942847632
-
Development of a histone deacetylase 6 inhibitor and its biological effects
-
Lee J-H, Yao Y, Mahendran A, Ngo L, Venta-Perez G, Choy ML, Breslow R, Marks PA., 2015. Development of a histone deacetylase 6 inhibitor and its biological effects. Proc Natl Acad Sci USA 112: 12005-12010.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 12005-12010
-
-
Lee, J.-H.1
Yao, Y.2
Mahendran, A.3
Ngo, L.4
Venta-Perez, G.5
Choy, M.L.6
Breslow, R.7
Marks, P.A.8
-
129
-
-
36248933672
-
th Birthday
-
th Birthday. Mov Disord 22: S327-S334.
-
(2007)
Mov Disord
, vol.22
, pp. S327-S334
-
-
Lees, A.J.1
-
130
-
-
84927605569
-
Biomarkers of Alzheimer's disease and mild cognitive impairment: A current perspective
-
Lewczuk P, Mroczko B, Fagan A, Kornhuber J., 2015. Biomarkers of Alzheimer's disease and mild cognitive impairment: a current perspective. Adv Med Sci 60: 76-82.
-
(2015)
Adv Med Sci
, vol.60
, pp. 76-82
-
-
Lewczuk, P.1
Mroczko, B.2
Fagan, A.3
Kornhuber, J.4
-
131
-
-
84964508545
-
Synthetic bioactive substances
-
PCK, Mehta B.M. editors. Berlin, Springer-Verlag
-
Li S., 2015. Synthetic bioactive substances, In: PCK, Mehta BM, editors. Handbook of food chemistry, Berlin, Springer-Verlag. p 1-20.
-
(2015)
Handbook of Food Chemistry
, pp. 1-20
-
-
Li, S.1
-
132
-
-
84941173776
-
Lipoic acid protects dopaminergic neurons in LPS-induced Parkinson's disease model
-
Li Y-H, He Q, Yu J-z, Liu C-y, Feng L, Chai Z, Wang Q, Zhang H-z, Zhang G-X, Xiao B-g, et al., 2015. Lipoic acid protects dopaminergic neurons in LPS-induced Parkinson's disease model. Metab Brain Dis 30: 1217-1226.
-
(2015)
Metab Brain Dis
, vol.30
, pp. 1217-1226
-
-
Li, Y.-H.1
He, Q.2
Yu, J.-Z.3
Liu, C.-Y.4
Feng, L.5
Chai, Z.6
Wang, Q.7
Zhang, H.-Z.8
Zhang, G.-X.9
Xiao, B.-G.10
-
133
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin M, Beal MF., 2006. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443: 787-795.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.1
Beal, M.F.2
-
134
-
-
84941944128
-
Mitochondria, autophagy and age-associated neurodegenerative diseases: New insights into a complex interplay
-
Lionaki E, Markaki M, Palikaras K, Tavernarakis N., 2015. Mitochondria, autophagy and age-associated neurodegenerative diseases: new insights into a complex interplay. BBA-Bioenergetics 1847: 1412-1423.
-
(2015)
BBA-Bioenergetics
, vol.1847
, pp. 1412-1423
-
-
Lionaki, E.1
Markaki, M.2
Palikaras, K.3
Tavernarakis, N.4
-
135
-
-
0037133319
-
Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and or R-α-lipoic acid
-
Liu J, Killilea DW, Ames BN., 2002a. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and or R-α-lipoic acid. Proc Natl Acad Sci USA 99: 1876-1881.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1876-1881
-
-
Liu, J.1
Killilea, D.W.2
Ames, B.N.3
-
136
-
-
0037133283
-
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-α-lipoic acid
-
Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN., 2002b. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-α-lipoic acid. Proc Natl Acad Sci USA 99: 2356-2361.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2356-2361
-
-
Liu, J.1
Head, E.2
Gharib, A.M.3
Yuan, W.4
Ingersoll, R.T.5
Hagen, T.M.6
Cotman, C.W.7
Ames, B.N.8
-
137
-
-
84887100129
-
Epigenetic studies in Alzheimer's Disease: Current findings, caveats, and considerations for future studies
-
Lunnon K, Mill J., 2013. Epigenetic studies in Alzheimer's Disease: current findings, caveats, and considerations for future studies. Am J Med Genet Part B 162B: 789-799.
-
(2013)
Am J Med Genet Part B
, vol.162 B
, pp. 789-799
-
-
Lunnon, K.1
Mill, J.2
-
138
-
-
51449084024
-
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease
-
Maczurek A, Hager K, Kenklies M, Sharman M, Martins R, Engel J, Carlson DA, Münch G., 2008. Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Adv Drug Deliver Rev 60: 1463-1470.
-
(2008)
Adv Drug Deliver Rev
, vol.60
, pp. 1463-1470
-
-
MacZurek, A.1
Hager, K.2
Kenklies, M.3
Sharman, M.4
Martins, R.5
Engel, J.6
Carlson, D.A.7
Münch, G.8
-
139
-
-
84859988979
-
Impaired mitochondrial function in psychiatric disorders
-
Manji H, Kato T, Di Prospero NA, Ness S, Beal MF, Krams M, Chen G., 2012. Impaired mitochondrial function in psychiatric disorders. Nat Rev Neurosci 13: 293-307.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 293-307
-
-
Manji, H.1
Kato, T.2
Di Prospero, N.A.3
Ness, S.4
Beal, M.F.5
Krams, M.6
Chen, G.7
-
140
-
-
84898447902
-
Plasma phospholipids identify antecedent memory impairment in older adults
-
Mapstone M, Cheema AK, Fiandaca MS, Zhong X, Mhyre TR, MacArthur LH, Hall WJ, Fisher SG, Peterson DR, Haley JM, et al., 2014. Plasma phospholipids identify antecedent memory impairment in older adults. Nat Med 20: 415-418.
-
(2014)
Nat Med
, vol.20
, pp. 415-418
-
-
Mapstone, M.1
Cheema, A.K.2
Fiandaca, M.S.3
Zhong, X.4
Mhyre, T.R.5
MacArthur, L.H.6
Hall, W.J.7
Fisher, S.G.8
Peterson, D.R.9
Haley, J.M.10
-
141
-
-
84946761723
-
Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease
-
Maqbool M, Mobashir M, Hoda N., 2016. Pivotal role of glycogen synthase kinase-3: a therapeutic target for Alzheimer's disease. Eur J Med Chem 107: 63-81.
-
(2016)
Eur J Med Chem
, vol.107
, pp. 63-81
-
-
Maqbool, M.1
Mobashir, M.2
Hoda, N.3
-
142
-
-
79958769568
-
Epigenetic mechanisms in Alzheimer's disease
-
Mastroeni D, Grover A, Delvaux E, Whiteside C, Coleman PD, Rogers J., 2011. Epigenetic mechanisms in Alzheimer's disease. Neurobiol Aging 32: 1161-1180.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1161-1180
-
-
Mastroeni, D.1
Grover, A.2
Delvaux, E.3
Whiteside, C.4
Coleman, P.D.5
Rogers, J.6
-
143
-
-
84940794366
-
Controlled and impaired mitochondrial quality in neurons: Molecular physiology and prospective pharmacology
-
Matic I, Strobbe D, Frison M, Campanella M., 2015. Controlled and impaired mitochondrial quality in neurons: molecular physiology and prospective pharmacology. Pharmacol Res 99: 410-424.
-
(2015)
Pharmacol Res
, vol.99
, pp. 410-424
-
-
Matic, I.1
Strobbe, D.2
Frison, M.3
Campanella, M.4
-
144
-
-
84947080762
-
Neuro-immune dysfunction during brain aging: New insights in microglial cell regulation
-
Matt SM, Johnson RW., 2016. Neuro-immune dysfunction during brain aging: new insights in microglial cell regulation. Curr Opin Pharmacol 26: 96-101.
-
(2016)
Curr Opin Pharmacol
, vol.26
, pp. 96-101
-
-
Matt, S.M.1
Johnson, R.W.2
-
145
-
-
84904093112
-
Lipoic acid biosynthesis defects
-
Mayr JA, Feichtinger RG, Tort F, Wolfgang Sperl W., 2014. Lipoic acid biosynthesis defects. J Inherit Metab Dis 37: 553-563.
-
(2014)
J Inherit Metab Dis
, vol.37
, pp. 553-563
-
-
Mayr, J.A.1
Feichtinger, R.G.2
Tort, F.3
Wolfgang Sperl, W.4
-
146
-
-
84897863239
-
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
-
McLelland G-L, Soubannier V, Chen CX, McBride HM, Fon EA., 2014. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J 33: 282-295.
-
(2014)
EMBO J
, vol.33
, pp. 282-295
-
-
McLelland, G.-L.1
Soubannier, V.2
Chen, C.X.3
McBride, H.M.4
Fon, E.A.5
-
147
-
-
84858148877
-
Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease
-
Mecocci P, Polidori MC., 2012. Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease. BBA-Mol Basis Dis 1822: 631-638.
-
(2012)
BBA-Mol Basis Dis
, vol.1822
, pp. 631-638
-
-
Mecocci, P.1
Polidori, M.C.2
-
148
-
-
84940719026
-
Mitochondrial degradation and energy metabolism
-
Melser S, Lavie J, Bénard G., 2015. Mitochondrial degradation and energy metabolism. BBA-Mol Cell Res 1853: 2812-2821.
-
(2015)
BBA-Mol Cell Res
, vol.1853
, pp. 2812-2821
-
-
Melser, S.1
Lavie, J.2
Bénard, G.3
-
149
-
-
84943259879
-
Microglial malfunction: The third rail in the development of Alzheimer's disease
-
Mhatre SD, Tsai CA, Rubin AJ, James ML, Andreasson KI., 2015. Microglial malfunction: the third rail in the development of Alzheimer's disease. Trends Neurosci 38: 621-636.
-
(2015)
Trends Neurosci
, vol.38
, pp. 621-636
-
-
Mhatre, S.D.1
Tsai, C.A.2
Rubin, A.J.3
James, M.L.4
Andreasson, K.I.5
-
150
-
-
84875217416
-
An epigenetic framework for neurodevelopmental disorders: From pathogenesis to potential therapy
-
Millan MJ., 2013. An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy. Neuropharmacology 68: 2-82.
-
(2013)
Neuropharmacology
, vol.68
, pp. 2-82
-
-
Millan, M.J.1
-
151
-
-
77949406726
-
The puzzling rise and fall of a dark-horse Alzheimer's drug
-
Miller G., 2010. The puzzling rise and fall of a dark-horse Alzheimer's drug. Science 327: 1309.
-
(2010)
Science
, vol.327
, pp. 1309
-
-
Miller, G.1
-
152
-
-
84860578029
-
Mitochondria, diabetes, and Alzheimer's disease
-
Milone M., 2012. Mitochondria, diabetes, and Alzheimer's disease. Diabetes 61: 991-992.
-
(2012)
Diabetes
, vol.61
, pp. 991-992
-
-
Milone, M.1
-
153
-
-
84910141948
-
Mitochondrial dynamics and inheritance during cell division, development and disease
-
Mishra P, Chan DC., 2014. Mitochondrial dynamics and inheritance during cell division, development and disease. Nat Rev Mol Cell Bio 15: 634-646.
-
(2014)
Nat Rev Mol Cell Bio
, vol.15
, pp. 634-646
-
-
Mishra, P.1
Chan, D.C.2
-
154
-
-
84951837246
-
Mitochondrial proteins moonlighting in the nucleus
-
Monaghan RM, Whitmarsh AJ., 2015. Mitochondrial proteins moonlighting in the nucleus. Trends Biochem Sci 40: 728-735.
-
(2015)
Trends Biochem Sci
, vol.40
, pp. 728-735
-
-
Monaghan, R.M.1
Whitmarsh, A.J.2
-
155
-
-
84887966412
-
Predictors of Parkinson's disease dementia: Towards targeted therapies for a heterogeneous disease
-
Moore SF, Barker RA., 2014. Predictors of Parkinson's disease dementia: towards targeted therapies for a heterogeneous disease. Parkinsonism Relat Disord 20S1: S104-S107.
-
(2014)
Parkinsonism Relat Disord
, vol.201
, pp. S104-S107
-
-
Moore, S.F.1
Barker, R.A.2
-
156
-
-
84958811524
-
Epigenetic treatment of neuropsychiatric disorders: Autism and Schizophrenia
-
press
-
Moos WH, Maneta E, Pinkert CA, Irwin MH, Hoffman ME, Faller DV, Steliou K., 2016. Epigenetic treatment of neuropsychiatric disorders: Autism and Schizophrenia. Drug Dev Res, in press.
-
(2016)
Drug Dev Res
-
-
Moos, W.H.1
Maneta, E.2
Pinkert, C.A.3
Irwin, M.H.4
Hoffman, M.E.5
Faller, D.V.6
Steliou, K.7
-
157
-
-
71849088759
-
Mitochondria: A therapeutic target in neurodegeneration
-
Moreira PI, Zhu X, Wang X, Lee H-g, Nunomura A, Petersen RB, Perry G, Smith MA., 2010. Mitochondria: a therapeutic target in neurodegeneration. BBA-Mol Basis Dis 1802: 212-220.
-
(2010)
BBA-Mol Basis Dis
, vol.1802
, pp. 212-220
-
-
Moreira, P.I.1
Zhu, X.2
Wang, X.3
Lee, H.-G.4
Nunomura, A.5
Petersen, R.B.6
Perry, G.7
Smith, M.A.8
-
158
-
-
84903441756
-
Is Alzheimer's disease a systemic disease?
-
Morris JK, Honea RA, Vidoni ED, Swerdlow RH, Burns JM., 2014. Is Alzheimer's disease a systemic disease? BBA-Mol Basis Dis 1842: 1340-1349.
-
(2014)
BBA-Mol Basis Dis
, vol.1842
, pp. 1340-1349
-
-
Morris, J.K.1
Honea, R.A.2
Vidoni, E.D.3
Swerdlow, R.H.4
Burns, J.M.5
-
159
-
-
84865153960
-
Burden of Alzheimer's disease-related mortality in the United States, 1999-2008
-
Moschetti K, Cummings PL, Sorvillo F, Kuo T., 2012. Burden of Alzheimer's disease-related mortality in the United States, 1999-2008. J Am Geriatr Soc 60: 1509-1514.
-
(2012)
J Am Geriatr Soc
, vol.60
, pp. 1509-1514
-
-
Moschetti, K.1
Cummings, P.L.2
Sorvillo, F.3
Kuo, T.4
-
160
-
-
84872730067
-
Alzheimer's therapeutics: Continued clinical failures question the validity of the amyloid hypothesis - But what lies beyond?
-
Mullane K, Williams M., 2013. Alzheimer's therapeutics: continued clinical failures question the validity of the amyloid hypothesis-but what lies beyond? Biochem Pharmacol 85: 289-305.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 289-305
-
-
Mullane, K.1
Williams, M.2
-
161
-
-
4444372351
-
Carnitine: Transport and physiological functions in the brain
-
Nałezcz KA, Miecz D, Berezowski V, Cecchelli R., 2004. Carnitine: transport and physiological functions in the brain. Mol Aspects Med 25: 551-567.
-
(2004)
Mol Aspects Med
, vol.25
, pp. 551-567
-
-
Nałezcz, K.A.1
Miecz, D.2
Berezowski, V.3
Cecchelli, R.4
-
162
-
-
84919335662
-
Increased acetyl and total histone levels in post-mortem Alzheimer's disease brain
-
Narayan PJ, Lill C, Faull R, Curtis MA, Dragunow M., 2015. Increased acetyl and total histone levels in post-mortem Alzheimer's disease brain. Neurobiol Dis 74: 281-294.
-
(2015)
Neurobiol Dis
, vol.74
, pp. 281-294
-
-
Narayan, P.J.1
Lill, C.2
Faull, R.3
Curtis, M.A.4
Dragunow, M.5
-
163
-
-
79954577302
-
Targeting mitochondrial dysfunction: Role for PINK1 and Parkin in mitochondrial quality control
-
Narendra DP, Youle RJ., 2011. Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control. Antioxid Redox Signal 14: 1929-1938.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 1929-1938
-
-
Narendra, D.P.1
Youle, R.J.2
-
164
-
-
84875278408
-
L-Acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors
-
Nasca C, Xenos D, Barone Y, Caruso A, Scaccianoce S, Matrisciano F, Battaglia G, Mathé AA, Pittaluga A, Lionetto L, et al., 2013. L-Acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. Proc Natl Acad Sci USA 110: 4804-4809.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 4804-4809
-
-
Nasca, C.1
Xenos, D.2
Barone, Y.3
Caruso, A.4
Scaccianoce, S.5
Matrisciano, F.6
Battaglia, G.7
Mathé, A.A.8
Pittaluga, A.9
Lionetto, L.10
-
165
-
-
84914145315
-
From microbe to man: The role of microbial short chain fatty acid metabolites in host cell biology
-
Natarajan N, Pluznick JL., 2014. From microbe to man: the role of microbial short chain fatty acid metabolites in host cell biology. Am J Physiol Cell Physiol 307: C979-C985.
-
(2014)
Am J Physiol Cell Physiol
, vol.307
, pp. C979-C985
-
-
Natarajan, N.1
Pluznick, J.L.2
-
166
-
-
84869874482
-
Trials with 'epigenetic' drugs: An update
-
Nebbioso A, Carafa V, Benedetti R, Lucia Altucci L., 2012. Trials with 'epigenetic' drugs: an update. Mol Oncol 6: 657-682.
-
(2012)
Mol Oncol
, vol.6
, pp. 657-682
-
-
Nebbioso, A.1
Carafa, V.2
Benedetti, R.3
Lucia Altucci, L.4
-
167
-
-
84948799893
-
Brain pathologies in extreme old age
-
Neltner JH, Abner EL, Jicha GA, Schmitt FA, Patel E, Poon LW, Marla G, Green RC, Davey A, Johnson MA, et al., 2016. Brain pathologies in extreme old age. Neurobiol Aging 37: 1-11.
-
(2016)
Neurobiol Aging
, vol.37
, pp. 1-11
-
-
Neltner, J.H.1
Abner, E.L.2
Jicha, G.A.3
Schmitt, F.A.4
Patel, E.5
Poon, L.W.6
Marla, G.7
Green, R.C.8
Davey, A.9
Johnson, M.A.10
-
168
-
-
84932627130
-
Neurodegenerative and fatiguing illnesses, infections and mitochondrial dysfunction: Use of natural supplements to improve mitochondrial function
-
Nicolson GL, Settineri R, Ellithorpe RR., 2014. Neurodegenerative and fatiguing illnesses, infections and mitochondrial dysfunction: use of natural supplements to improve mitochondrial function. Funct Food Health Dis 4: 23-65.
-
(2014)
Funct Food Health Dis
, vol.4
, pp. 23-65
-
-
Nicolson, G.L.1
Settineri, R.2
Ellithorpe, R.R.3
-
170
-
-
84863430453
-
Mitophagy: A complex mechanism of mitochondrial removal
-
Novak I., 2012. Mitophagy: a complex mechanism of mitochondrial removal. Antioxid Redox Sign 17: 794-802.
-
(2012)
Antioxid Redox Sign
, vol.17
, pp. 794-802
-
-
Novak, I.1
-
171
-
-
84949533347
-
Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons
-
Oettinghaus B, Schulz JM, Restelli LM, Licci M, Savoia C, Schmidt A, Schmitt K, Grimm A, Morè L, Hench J, et al., 2016. Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons. Nat Cell Differ 23: 18-28.
-
(2016)
Nat Cell Differ
, vol.23
, pp. 18-28
-
-
Oettinghaus, B.1
Schulz, J.M.2
Restelli, L.M.3
Licci, M.4
Savoia, C.5
Schmidt, A.6
Schmitt, K.7
Grimm, A.8
Morè, L.9
Hench, J.10
-
172
-
-
84918820798
-
Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice
-
Oliveras-Salvá M, Macchi F, Coessens V, Deleersnijder A, Gérard M, Van der Perren A, Van den Haute C, Baekelandt V., 2014. Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice. Neurobiol Aging 35: 2625-2636.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 2625-2636
-
-
Oliveras-Salvá, M.1
MacChi, F.2
Coessens, V.3
Deleersnijder, A.4
Gérard, M.5
Van Der Perren, A.6
Van Den Haute, C.7
Baekelandt, V.8
-
173
-
-
84946606692
-
Immunomodulation as a neuroprotective and therapeutic strategy for Parkinson's disease
-
Olson KE, Gendelman HE., 2016. Immunomodulation as a neuroprotective and therapeutic strategy for Parkinson's disease. Curr Opin Pharmacol 26: 87-95.
-
(2016)
Curr Opin Pharmacol
, vol.26
, pp. 87-95
-
-
Olson, K.E.1
Gendelman, H.E.2
-
175
-
-
84901933198
-
Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: Toward mitochondria-targeted clinical strategies. Oxid
-
Pagano G, Talamanca AA, Castello G, Cordero MD, d'Ischia M, Gadaleta MN, Pallardó FV, Petrovic S, Tiano L, Zatterale A., 2014. Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies. Oxid Med Cell Longev 2014: 1.
-
(2014)
Med Cell Longev
, vol.2014
, pp. 1
-
-
Pagano, G.1
Talamanca, A.A.2
Castello, G.3
Cordero, M.D.4
D'Ischia, M.5
Gadaleta, M.N.6
Pallardó, F.V.7
Petrovic, S.8
Tiano, L.9
Zatterale, A.10
-
176
-
-
84901826020
-
Mitochondrial homeostasis: The interplay between mitophagy and mitochondrial biogenesis
-
Palikaras K, Tavernarakis N., 2014. Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis. Exp Gerontol 56: 182-188.
-
(2014)
Exp Gerontol
, vol.56
, pp. 182-188
-
-
Palikaras, K.1
Tavernarakis, N.2
-
177
-
-
84910627065
-
Efficacy of α-lipoic acid in diabetic retinopathy
-
Papanas N, Ziegler D., 2015. Efficacy of α-lipoic acid in diabetic retinopathy. Expert Opin Pharmacother 15: 2721-2731.
-
(2015)
Expert Opin Pharmacother
, vol.15
, pp. 2721-2731
-
-
Papanas, N.1
Ziegler, D.2
-
178
-
-
78651284859
-
D-Galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice
-
Parameshwaran K, Irwin MH, Steliou K, Pinkert CA., 2010. D-Galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice. Rejuv Res 13: 729-735.
-
(2010)
Rejuv Res
, vol.13
, pp. 729-735
-
-
Parameshwaran, K.1
Irwin, M.H.2
Steliou, K.3
Pinkert, C.A.4
-
179
-
-
84857699370
-
Protection by an antioxidant of rotenone-induced neuromotor decline, reactive oxygen species generation and cellular stress in mouse brain
-
Parameshwaran K, Irwin MH, Steliou K, Pinkert CA., 2012. Protection by an antioxidant of rotenone-induced neuromotor decline, reactive oxygen species generation and cellular stress in mouse brain. Pharmacol Biochem Behav 101: 487-492.
-
(2012)
Pharmacol Biochem Behav
, vol.101
, pp. 487-492
-
-
Parameshwaran, K.1
Irwin, M.H.2
Steliou, K.3
Pinkert, C.A.4
-
180
-
-
84927758763
-
Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition
-
Parameshwaran K, Irwin MH, Steliou K, Suppiramaniam V, Pinkert CA., 2015. Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition. Drug Dev Res 76: 72-81.
-
(2015)
Drug Dev Res
, vol.76
, pp. 72-81
-
-
Parameshwaran, K.1
Irwin, M.H.2
Steliou, K.3
Suppiramaniam, V.4
Pinkert, C.A.5
-
181
-
-
84947596818
-
α-Lipoic acid as a triglyceride-lowering nutraceutical
-
Pashaj A, Xia M, Moreau R., 2015. α-Lipoic acid as a triglyceride-lowering nutraceutical. Can J Physiol Pharmacol 93: 1.
-
(2015)
Can J Physiol Pharmacol
, vol.93
, pp. 1
-
-
Pashaj, A.1
Xia, M.2
Moreau, R.3
-
182
-
-
84941734879
-
Mitochondrial dysfunction in aging: Much progress but many unresolved questions
-
Payne BAI, Chinnery PF., 2015. Mitochondrial dysfunction in aging: much progress but many unresolved questions. BBA-Bioenergetics 1847: 1347-1353.
-
(2015)
BBA-Bioenergetics
, vol.1847
, pp. 1347-1353
-
-
Payne, B.A.I.1
Chinnery, P.F.2
-
183
-
-
77952168294
-
Altered histone acetylation is associated with age-dependent memory impairment in mice
-
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Wittnam JL, Gogol-Doering A, Opitz L, et al., 2010. Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 328: 753-756.
-
(2010)
Science
, vol.328
, pp. 753-756
-
-
Peleg, S.1
Sananbenesi, F.2
Zovoilis, A.3
Burkhardt, S.4
Bahari-Javan, S.5
Agis-Balboa, R.C.6
Wittnam, J.L.7
Gogol-Doering, A.8
Opitz, L.9
-
184
-
-
84926334923
-
Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection
-
Pellegrino MW, Haynes CM., 2015. Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection. BMC Biology 13: 22.
-
(2015)
BMC Biology
, vol.13
, pp. 22
-
-
Pellegrino, M.W.1
Haynes, C.M.2
-
185
-
-
84867571826
-
Mitochondria and Alzheimer's disease
-
Piaceri I, Rinnoci V, Bagnoli S, Failli Y, Sorbi S., 2012. Mitochondria and Alzheimer's disease. J Neurol Sci 322: 31-34.
-
(2012)
J Neurol Sci
, vol.322
, pp. 31-34
-
-
Piaceri, I.1
Rinnoci, V.2
Bagnoli, S.3
Failli, Y.4
Sorbi, S.5
-
186
-
-
84921369563
-
The roles of PINK1, Parkin, and mitochondrial fidelity in Parkinson's disease
-
Pickrell AM, Youle RJ., 2015. The roles of PINK1, Parkin, and mitochondrial fidelity in Parkinson's disease. Neuron 85: 257-273.
-
(2015)
Neuron
, vol.85
, pp. 257-273
-
-
Pickrell, A.M.1
Youle, R.J.2
-
187
-
-
38849090084
-
Synthesis and characterization of carnitine nitro-derivatives
-
Piermatti O, Fringuelli F, Pochini L, Indiveri C, Palmerini CA., 2008. Synthesis and characterization of carnitine nitro-derivatives. Bioorg Med Chem 16: 1444-1451.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 1444-1451
-
-
Piermatti, O.1
Fringuelli, F.2
Pochini, L.3
Indiveri, C.4
Palmerini, C.A.5
-
188
-
-
84901828447
-
Mitochondrial import and degradation of amyloid-β peptide
-
Pinho CM, Teixeira PF, Glaser E., 2014. Mitochondrial import and degradation of amyloid-β peptide. BBA-Bioenergetics 1837: 1069-1174.
-
(2014)
BBA-Bioenergetics
, vol.1837
, pp. 1069-1174
-
-
Pinho, C.M.1
Teixeira, P.F.2
Glaser, E.3
-
189
-
-
84903267268
-
Mitochondrial genome changes and neurodegenerative diseases
-
Pinto M, Moraes CT., 2014. Mitochondrial genome changes and neurodegenerative diseases. BBA-Mol Basis Dis 1842: 1198-1207.
-
(2014)
BBA-Mol Basis Dis
, vol.1842
, pp. 1198-1207
-
-
Pinto, M.1
Moraes, C.T.2
-
190
-
-
84947927552
-
The immune system in traumatic brain injury
-
Plesnila N., 2016. The immune system in traumatic brain injury. Curr Opin Pharmacol 26: 110-117.
-
(2016)
Curr Opin Pharmacol
, vol.26
, pp. 110-117
-
-
Plesnila, N.1
-
191
-
-
84964534124
-
Simultaneous activation of Nrf2 and elevation of antioxidant chemicals in management of post-traumatic stress disorders and traumatic brain injury
-
Prasad KN., 2015. Simultaneous activation of Nrf2 and elevation of antioxidant chemicals in management of post-traumatic stress disorders and traumatic brain injury. Balkan Military Med Rev 18: 116-127.
-
(2015)
Balkan Military Med Rev
, vol.18
, pp. 116-127
-
-
Prasad, K.N.1
-
193
-
-
84919870857
-
Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases
-
Qureshi IA, Mehler MF., 2014. Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases. Neurotherapeutics 11: 708-720.
-
(2014)
Neurotherapeutics
, vol.11
, pp. 708-720
-
-
Qureshi, I.A.1
Mehler, M.F.2
-
194
-
-
84950280499
-
Potential compounds for the treatment of mitochondrial disease
-
Rai PK, Russell OM, Lightowlers RN, Turnbull DM., 2015. Potential compounds for the treatment of mitochondrial disease. Br Med Bull 116: 5-18.
-
(2015)
Br Med Bull
, vol.116
, pp. 5-18
-
-
Rai, P.K.1
Russell, O.M.2
Lightowlers, R.N.3
Turnbull, D.M.4
-
195
-
-
77649183649
-
Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger
-
Ralph SJ, Rodríguez-Enríquez S, Neuzil J, Moreno-Sánchez R., 2010. Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger. Mol Aspects Med 31: 29-59.
-
(2010)
Mol Aspects Med
, vol.31
, pp. 29-59
-
-
Ralph, S.J.1
Rodríguez-Enríquez, S.2
Neuzil, J.3
Moreno-Sánchez, R.4
-
196
-
-
84858281225
-
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics
-
Reddy PH, Tripathi R, Troung Q, Tirumala K, Reddy TP, Anekonda V, Shirendeb UP, Calkins MJ, Reddy AP, Mao P, et al., 2012. Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics. BBA-Mol Basis Dis 1822: 639-649.
-
(2012)
BBA-Mol Basis Dis
, vol.1822
, pp. 639-649
-
-
Reddy, P.H.1
Tripathi, R.2
Troung, Q.3
Tirumala, K.4
Reddy, T.P.5
Anekonda, V.6
Shirendeb, U.P.7
Calkins, M.J.8
Reddy, A.P.9
Mao, P.10
-
197
-
-
84901768886
-
Mitophagy mechanisms and role in human diseases
-
Redmann M, Dodson M, Boyer-Guittaut M, Darley-Usmar V, Zhang J., 2014. Mitophagy mechanisms and role in human diseases. Int J Biochem Cell Biol 53: 127-133.
-
(2014)
Int J Biochem Cell Biol
, vol.53
, pp. 127-133
-
-
Redmann, M.1
Dodson, M.2
Boyer-Guittaut, M.3
Darley-Usmar, V.4
Zhang, J.5
-
198
-
-
84887615195
-
L-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders
-
Ribas GS, Vargas CR, Wajner M., 2014. L-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders. Gene 533: 469-476.
-
(2014)
Gene
, vol.533
, pp. 469-476
-
-
Ribas, G.S.1
Vargas, C.R.2
Wajner, M.3
-
199
-
-
84859712559
-
Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
-
Ricobaraza A, Cuadrado-Tejedor M, Marco S, Pérez-Otanõ I, García-Osta A., 2012. Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease. Hippocampus 22: 1040-1050.
-
(2012)
Hippocampus
, vol.22
, pp. 1040-1050
-
-
Ricobaraza, A.1
Cuadrado-Tejedor, M.2
Marco, S.3
Pérez-Otanõ, I.4
García-Osta, A.5
-
200
-
-
84949579822
-
Can aging be 'drugged'?
-
Riera CE, Dillin A., 2016. Can aging be 'drugged'? Nat Med 21: 1400-1405.
-
(2016)
Nat Med
, vol.21
, pp. 1400-1405
-
-
Riera, C.E.1
Dillin, A.2
-
201
-
-
70349554140
-
Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag
-
Ripcke J, Zarse K, Ristow M, Birringer M., 2009. Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag. ChemBioChem 10: 1698-1696.
-
(2009)
ChemBioChem
, vol.10
, pp. 1698-1696
-
-
Ripcke, J.1
Zarse, K.2
Ristow, M.3
Birringer, M.4
-
202
-
-
84872146192
-
Direct and indirect antioxidant properties of alpha-lipoic acid and therapeutic potential
-
Rochette L, Ghibu S, Richard C, Zeller M, Cottin Y, Vergely C., 2013. Direct and indirect antioxidant properties of alpha-lipoic acid and therapeutic potential. Mol Nutr Food Res 57: 114-125.
-
(2013)
Mol Nutr Food Res
, vol.57
, pp. 114-125
-
-
Rochette, L.1
Ghibu, S.2
Richard, C.3
Zeller, M.4
Cottin, Y.5
Vergely, C.6
-
203
-
-
84947552707
-
Alpha-lipoic acid: Molecular mechanisms and therapeutic potential in diabetes
-
Rochette L, Ghibu S, Muresan A, Vergely C., 2015. Alpha-lipoic acid: molecular mechanisms and therapeutic potential in diabetes. Can J Physiol Pharmacol 93: 1.
-
(2015)
Can J Physiol Pharmacol
, vol.93
, pp. 1
-
-
Rochette, L.1
Ghibu, S.2
Muresan, A.3
Vergely, C.4
-
204
-
-
84899647287
-
Epigenetics and migraine; Complex mitochondrial interactions contributing to disease susceptibility
-
Roos-Araujo D, Stuart S, Lea RA, Haupt LM, Griffiths LR., 2014. Epigenetics and migraine; complex mitochondrial interactions contributing to disease susceptibility. Gene 533: 1-7.
-
(2014)
Gene
, vol.533
, pp. 1-7
-
-
Roos-Araujo, D.1
Stuart, S.2
Lea, R.A.3
Haupt, L.M.4
Griffiths, L.R.5
-
205
-
-
71549116704
-
Mitochondria in the elderly: Is acetylcarnitine a rejuvenator?
-
Rosca MG, Lemieux H, Hoppel CL,. 2009. Mitochondria in the elderly: Is acetylcarnitine a rejuvenator? Adv Drug Deliv Rev 61: 1332-1342.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1332-1342
-
-
Rosca, M.G.1
Lemieux, H.2
Hoppel, C.L.3
-
206
-
-
84964541716
-
Lysine (K)-deacetylase inhibitors: The real next step to neuropsychiatric and neurodegenerative disorders?
-
Rosenstock TR., 2013. Lysine (K)-deacetylase inhibitors: the real next step to neuropsychiatric and neurodegenerative disorders? Cell Biol 2: a8.
-
(2013)
Cell Biol
, vol.2
, pp. a8
-
-
Rosenstock, T.R.1
-
207
-
-
80054960254
-
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease
-
Rosini M, Simoni E, Bartolini M, Tarozzi A, Matera R, Milelli A, Hrelia P, Andrisano V, Bolognesi ML, Melchiorre C., 2011. Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. Eur J Med Chem 46: 5435-5442.
-
(2011)
Eur J Med Chem
, vol.46
, pp. 5435-5442
-
-
Rosini, M.1
Simoni, E.2
Bartolini, M.3
Tarozzi, A.4
Matera, R.5
Milelli, A.6
Hrelia, P.7
Andrisano, V.8
Bolognesi, M.L.9
Melchiorre, C.10
-
208
-
-
80755174513
-
Countrywide strategic plans on Alzheimer's disease: Developing the framework for the international battle against Alzheimer's disease
-
Rosow K, Holzapfel A, Karlawish JH, Baumgart M, Baind LJ, Khachaturian AS., 2011. Countrywide strategic plans on Alzheimer's disease: developing the framework for the international battle against Alzheimer's disease. Alzheimer's Dement 7: 615-621.
-
(2011)
Alzheimer's Dement
, vol.7
, pp. 615-621
-
-
Rosow, K.1
Holzapfel, A.2
Karlawish, J.H.3
Baumgart, M.4
Baind, L.J.5
Khachaturian, A.S.6
-
209
-
-
84947562946
-
Global neurotrauma research challenges and opportunities
-
Rubiano AM, Carney N, Chesnut R, Puyana JC., 2015. Global neurotrauma research challenges and opportunities. Nature 527: S193-S197.
-
(2015)
Nature
, vol.527
, pp. S193-S197
-
-
Rubiano, A.M.1
Carney, N.2
Chesnut, R.3
Puyana, J.C.4
-
210
-
-
84951128922
-
Alzheimer's disease in the 100 years since Alzheimer's death
-
Ryan NS, Rossor MN, Fox NC., 2015. Alzheimer's disease in the 100 years since Alzheimer's death. Brain 138: 3816-3821.
-
(2015)
Brain
, vol.138
, pp. 3816-3821
-
-
Ryan, N.S.1
Rossor, M.N.2
Fox, N.C.3
-
211
-
-
84932625953
-
Epigenetic study of Parkinson's disease in experimental animal model
-
Salama AF, Ibrahim W, Tousson E, Sakr S, Masoud A, Akela MA, Abd El-Rahman MA., 2015. Epigenetic study of Parkinson's disease in experimental animal model. Int J Clin Exp Neurol 3: 11-20.
-
(2015)
Int J Clin Exp Neurol
, vol.3
, pp. 11-20
-
-
Salama, A.F.1
Ibrahim, W.2
Tousson, E.3
Sakr, S.4
Masoud, A.5
Akela, M.A.6
Abd El-Rahman, M.A.7
-
212
-
-
84902685602
-
Krebs cycle intermediates regulate DNA and histone methylation: Epigenetic impact on the aging process
-
Salminen A, Kauppinen A, Hiltunen M, Kaarnirant K., 2014. Krebs cycle intermediates regulate DNA and histone methylation: epigenetic impact on the aging process. Ageing Res Rev 15: 45-65.
-
(2014)
Ageing Res Rev
, vol.15
, pp. 45-65
-
-
Salminen, A.1
Kauppinen, A.2
Hiltunen, M.3
Kaarnirant, K.4
-
214
-
-
84856108244
-
Alzheimer's therapeutics: Translation of preclinical science to clinical drug development
-
Savonenko AV, Melnikova T, Hiatt A, Li T, Worley PF, Troncoso JC, Wong PC, Price DL., 2012. Alzheimer's therapeutics: translation of preclinical science to clinical drug development. Nat Neuropsychopharmacol 37: 261-277.
-
(2012)
Nat Neuropsychopharmacol
, vol.37
, pp. 261-277
-
-
Savonenko, A.V.1
Melnikova, T.2
Hiatt, A.3
Li, T.4
Worley, P.F.5
Troncoso, J.C.6
Wong, P.C.7
Price, D.L.8
-
215
-
-
84860840558
-
Mitochondrial diseases
-
Schapira AHV., 2012. Mitochondrial diseases. Lancet 379: 1825-1834.
-
(2012)
Lancet
, vol.379
, pp. 1825-1834
-
-
Schapira, A.H.V.1
-
216
-
-
84901833411
-
Autophagy and human disease: Emerging themes
-
Schneider JL, Cuervo AM., 2014. Autophagy and human disease: emerging themes. Curr Opin Genet Dev 26: 16-23.
-
(2014)
Curr Opin Genet Dev
, vol.26
, pp. 16-23
-
-
Schneider, J.L.1
Cuervo, A.M.2
-
217
-
-
84871417031
-
Role of mitochondrial homeostasis and dynamics in Alzheimer's disease
-
Lezi E
-
Selfridge JE, Lezi E, Lu J, Swerdlow RH., 2013. Role of mitochondrial homeostasis and dynamics in Alzheimer's disease. Neurobiol Dis 51: 3-12.
-
(2013)
Neurobiol Dis
, vol.51
, pp. 3-12
-
-
Selfridge, J.E.1
Lu, J.2
Swerdlow, R.H.3
-
218
-
-
84866456583
-
Preventing Alzheimer's disease
-
Selkoe DJ., 2012. Preventing Alzheimer's disease. Science 337: 1488-1491.
-
(2012)
Science
, vol.337
, pp. 1488-1491
-
-
Selkoe, D.J.1
-
219
-
-
84908210952
-
Alzheimer's disease and epigenetic diet
-
Sezgin Z, Dincer Y., 2014. Alzheimer's disease and epigenetic diet. Neurochem Int 78: 105-116.
-
(2014)
Neurochem Int
, vol.78
, pp. 105-116
-
-
Sezgin, Z.1
Dincer, Y.2
-
220
-
-
84869883284
-
A vitamin for the brain
-
Shearer KD, Stoney PN, Morgan PJ, McCaffery PJ., 2012. A vitamin for the brain. Trends Neurosci 35: 733-741.
-
(2012)
Trends Neurosci
, vol.35
, pp. 733-741
-
-
Shearer, K.D.1
Stoney, P.N.2
Morgan, P.J.3
McCaffery, P.J.4
-
221
-
-
67249089661
-
The effect of acetyl-L-carnitine and R-α-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease
-
Shenk JC, Liu J, Fischbach K, Xu K, Puchowicz M, Obrenovich ME, Gasimov E, Alvarez LM, Ames BN, LaManna JC, et al., 2009. The effect of acetyl-L-carnitine and R-α-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease. J Neurol Sci 283: 199-206.
-
(2009)
J Neurol Sci
, vol.283
, pp. 199-206
-
-
Shenk, J.C.1
Liu, J.2
Fischbach, K.3
Xu, K.4
Puchowicz, M.5
Obrenovich, M.E.6
Gasimov, E.7
Alvarez, L.M.8
Ames, B.N.9
LaManna, J.C.10
-
222
-
-
84954619912
-
Pivotal trials for β-secretase inhibitors in Alzheimer's
-
Sheridan C., 2015. Pivotal trials for β-secretase inhibitors in Alzheimer's. Nat Biotechnol 33: 115-116.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 115-116
-
-
Sheridan, C.1
-
223
-
-
84938544529
-
ALCAR exerts neuroprotective and pro-neurogenic effects by inhibition of glial activation and oxidative stress via activation of the Wnt/β-catenin signaling in Parkinsonian rats
-
July 30
-
Singh S, Mishra A, Shukla S., 2015. ALCAR exerts neuroprotective and pro-neurogenic effects by inhibition of glial activation and oxidative stress via activation of the Wnt/β-catenin signaling in Parkinsonian rats. Mol Neurobiol (July 30, doi: 10.1007/s12035-015-9361-5).
-
(2015)
Mol Neurobiol
-
-
Singh, S.1
Mishra, A.2
Shukla, S.3
-
224
-
-
84964430836
-
-
London: Springer-Verlag
-
Smith R, Mill J., 2011. Epigenetics and chronic diseases: an overview. In: Roach HI, Bronner F, Oreffo ROC, editors. Epigenetic aspects of chronic diseases. London: Springer-Verlag.
-
(2011)
Epigenetics and Chronic Diseases: An Overview. In: Roach HI, Bronner F, Oreffo ROC, Editors. Epigenetic Aspects of Chronic Diseases
-
-
Smith, R.1
Mill, J.2
-
225
-
-
84907024448
-
Animal models of dementia and cognitive dysfunction
-
Sodhi N, Jaggi AS, Singh N., 2014. Animal models of dementia and cognitive dysfunction. Life Sci 109: 73-86.
-
(2014)
Life Sci
, vol.109
, pp. 73-86
-
-
Sodhi, N.1
Jaggi, A.S.2
Singh, N.3
-
226
-
-
84868530905
-
RAGE in tissue homeostasis, repair and regeneration
-
Sorci G, Riuzzi F, Giambanco I, Donato R., 2013. RAGE in tissue homeostasis, repair and regeneration. BBA-Mol Cell Res 1833: 101-109.
-
(2013)
BBA-Mol Cell Res
, vol.1833
, pp. 101-109
-
-
Sorci, G.1
Riuzzi, F.2
Giambanco, I.3
Donato, R.4
-
227
-
-
84875392161
-
Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer's disease
-
Sozio P, Cerasa LS, Laserra S, Cacciatore I, Cornacchia C, Di Filippo ES, Fulle S, Fontana A, Di Crescenzo A, Grilli M, et al., 2013. Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer's disease. Eur J Pharm Sci 49: 187-198.
-
(2013)
Eur J Pharm Sci
, vol.49
, pp. 187-198
-
-
Sozio, P.1
Cerasa, L.S.2
Laserra, S.3
Cacciatore, I.4
Cornacchia, C.5
Di Filippo, E.S.6
Fulle, S.7
Fontana, A.8
Di Crescenzo, A.9
Grilli, M.10
-
230
-
-
84860889760
-
The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases
-
Stacpoole PW., 2012. The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases. Aging Cell 11: 371-377.
-
(2012)
Aging Cell
, vol.11
, pp. 371-377
-
-
Stacpoole, P.W.1
-
231
-
-
84926656581
-
Beyond mitophagy: Cytosolic PINK1 as a messenger of mitochondrial health
-
Steer EK, Dail MK, Chu CT., 2015. Beyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial health. Antioxid Redox Signal 22: 1047-1059.
-
(2015)
Antioxid Redox Signal
, vol.22
, pp. 1047-1059
-
-
Steer, E.K.1
Dail, M.K.2
Chu, C.T.3
-
232
-
-
70649112278
-
Lactic acid in cancer and mitochondrial disease
-
Steliou K, Perrine SP, Faller DV., 2009. Lactic acid in cancer and mitochondrial disease. Drug Dev Res 70: 499-511.
-
(2009)
Drug Dev Res
, vol.70
, pp. 499-511
-
-
Steliou, K.1
Perrine, S.P.2
Faller, D.V.3
-
233
-
-
85043492396
-
Butyrate histone deacetylase inhibitors
-
Steliou K, Boosalis MS, Perrine SP, Sangerman J, Faller DV., 2012. Butyrate histone deacetylase inhibitors. BioResearch Open Access. 1: 192-198.
-
(2012)
BioResearch Open Access.
, vol.1
, pp. 192-198
-
-
Steliou, K.1
Boosalis, M.S.2
Perrine, S.P.3
Sangerman, J.4
Faller, D.V.5
-
234
-
-
84932604305
-
Bioprotective Carnitinoids: Lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury
-
Steliou K, Faller DV, Pinkert CA, Irwin MH, Moos WH., 2015. Bioprotective Carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury. Drug Dev Res 76: 167-175.
-
(2015)
Drug Dev Res
, vol.76
, pp. 167-175
-
-
Steliou, K.1
Faller, D.V.2
Pinkert, C.A.3
Irwin, M.H.4
Moos, W.H.5
-
235
-
-
84922506220
-
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
-
Strappazzon F, Nazio F, Corrado M, Cianfanelli V, Romagnoli A, Fimia GM, Campello S, Nardacci R, Piacentini M, Campanella M, et al., 2015. AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Nat Cell Death Differ 22: 419-432.
-
(2015)
Nat Cell Death Differ
, vol.22
, pp. 419-432
-
-
Strappazzon, F.1
Nazio, F.2
Corrado, M.3
Cianfanelli, V.4
Romagnoli, A.5
Fimia, G.M.6
Campello, S.7
Nardacci, R.8
Piacentini, M.9
Campanella, M.10
-
236
-
-
84858770007
-
Old drug, new hope for Alzheimer's disease
-
Strittmatter WJ., 2012. Old drug, new hope for Alzheimer's disease. Science 335: 1447-1448.
-
(2012)
Science
, vol.335
, pp. 1447-1448
-
-
Strittmatter, W.J.1
-
237
-
-
77955090213
-
Abnormal mitochondrial dynamics - A novel therapeutic target for Alzheimer's disease?
-
Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X., 2010. Abnormal mitochondrial dynamics-A novel therapeutic target for Alzheimer's disease? Mol Neurobiol 41: 87-96.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 87-96
-
-
Su, B.1
Wang, X.2
Bonda, D.3
Perry, G.4
Smith, M.5
Zhu, X.6
-
238
-
-
1542723493
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
-
Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu R-M, Hagen TM., 2004. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci USA 101: 3381-3386.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3381-3386
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
Liu, H.4
Jaiswal, A.K.5
Liu, R.-M.6
Hagen, T.M.7
-
239
-
-
84948809269
-
Mitochondrial quality control as a therapeutic target
-
Suliman HB, Piantadosi CA., 2016. Mitochondrial quality control as a therapeutic target. Pharmacol Rev 68: 20-48.
-
(2016)
Pharmacol Rev
, vol.68
, pp. 20-48
-
-
Suliman, H.B.1
Piantadosi, C.A.2
-
240
-
-
84947802088
-
Measuring in vivo mitophagy
-
Sun N, Yun J, Liu J, Malide D, Liu C, Rovira II, Holmström KM, Fergusson MM, Yoo YH, Combs CA, et al., 2015. Measuring in vivo mitophagy. Mol Cell 60: 685-696.
-
(2015)
Mol Cell
, vol.60
, pp. 685-696
-
-
Sun, N.1
Yun, J.2
Liu, J.3
Malide, D.4
Liu, C.5
Rovira, I.I.6
Holmström, K.M.7
Fergusson, M.M.8
Yoo, Y.H.9
Combs, C.A.10
-
241
-
-
84868549261
-
Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease
-
Sung YM, Lee T, Yoon H, DiBattista AM, Song JM, Sohn Y, Moffat EI, Turner RS, Jung M, Kim J, et al., 2013. Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease. Exp Neurol 239: 192-201.
-
(2013)
Exp Neurol
, vol.239
, pp. 192-201
-
-
Sung, Y.M.1
Lee, T.2
Yoon, H.3
DiBattista, A.M.4
Song, J.M.5
Sohn, Y.6
Moffat, E.I.7
Turner, R.S.8
Jung, M.9
Kim, J.10
-
242
-
-
84903954689
-
A nuclear pyruvate dehydrogenase complex is important for the generation of Acetyl-CoA and histone acetylation
-
Sutendra G, Kinnaird A, Dromparis P, Paulin R, Stenson TH, Haromy A, Hashimoto K, Zhang N, Flaim E, Michelakis ED., 2014. A nuclear pyruvate dehydrogenase complex is important for the generation of Acetyl-CoA and histone acetylation. Cell 158: 84-97.
-
(2014)
Cell
, vol.158
, pp. 84-97
-
-
Sutendra, G.1
Kinnaird, A.2
Dromparis, P.3
Paulin, R.4
Stenson, T.H.5
Haromy, A.6
Hashimoto, K.7
Zhang, N.8
Flaim, E.9
Michelakis, E.D.10
-
243
-
-
84887009499
-
The emerging field of neuroepigenetics
-
Sweatt JD., 2013. The emerging field of neuroepigenetics. Neuron 80: 624-632.
-
(2013)
Neuron
, vol.80
, pp. 624-632
-
-
Sweatt, J.D.1
-
244
-
-
84860210262
-
Mitochondria and cell bioenergetics: Increasingly recognized components and a possible etiologic cause of Alzheimer's disease
-
Swerdlow RH., 2012. Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease. Antioxid Redox Sign 16: 1434-1455.
-
(2012)
Antioxid Redox Sign
, vol.16
, pp. 1434-1455
-
-
Swerdlow, R.H.1
-
245
-
-
84903304968
-
The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
-
Swerdlow RH, Burns JM, Khan SM., 2014. The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives. BBA-Mol Basis Dis 1842: 1219-1231.
-
(2014)
BBA-Mol Basis Dis
, vol.1842
, pp. 1219-1231
-
-
Swerdlow, R.H.1
Burns, J.M.2
Khan, S.M.3
-
246
-
-
84934443570
-
Prospects for the development of epigenetic drugs for CNS conditions
-
Szyf M., 2015. Prospects for the development of epigenetic drugs for CNS conditions. Nat Rev Drug Discov 14: 461-474.
-
(2015)
Nat Rev Drug Discov
, vol.14
, pp. 461-474
-
-
Szyf, M.1
-
247
-
-
34250664327
-
Drug evaluation: MitoQ - A mitochondria-targeted antioxidant
-
Tauskela JS., 2007. Drug evaluation: MitoQ-a mitochondria-targeted antioxidant. IDrugs 10: 399-412.
-
(2007)
IDrugs
, vol.10
, pp. 399-412
-
-
Tauskela, J.S.1
-
248
-
-
84862806815
-
Pharmacotherapies for Alzheimer's disease: Beyond cholinesterase inhibitors
-
Tayeb HO, Yang HD, Price BH, Tarazi FI., 2012. Pharmacotherapies for Alzheimer's disease: beyond cholinesterase inhibitors. Pharmacol Therapeut 134: 8-25.
-
(2012)
Pharmacol Therapeut
, vol.134
, pp. 8-25
-
-
Tayeb, H.O.1
Yang, H.D.2
Price, B.H.3
Tarazi, F.I.4
-
249
-
-
84969900554
-
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
-
Tebay LE, Robertson H, Durant ST, Vitale SR, Penning TM, Dinkova-Kostova AT, Hayes JD., 2015. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease. Free Radic Bio Med 88: 108-146.
-
(2015)
Free Radic Bio Med
, vol.88
, pp. 108-146
-
-
Tebay, L.E.1
Robertson, H.2
Durant, S.T.3
Vitale, S.R.4
Penning, T.M.5
Dinkova-Kostova, A.T.6
Hayes, J.D.7
-
251
-
-
69849093083
-
Focal nature of neurological disorders necessitates isotype-selective histone deacetylase (HDAC) inhibitors
-
Thomas EA., 2009. Focal nature of neurological disorders necessitates isotype-selective histone deacetylase (HDAC) inhibitors. Mol Neurobiol 40: 33-45.
-
(2009)
Mol Neurobiol
, vol.40
, pp. 33-45
-
-
Thomas, E.A.1
-
252
-
-
78649983748
-
Alzheimer's disease: Effects of β-amyloid on mitochondria
-
Tillement L, Lecanu L, Papadopoulos V., 2011. Alzheimer's disease: effects of β-amyloid on mitochondria. Mitochondrion 11: 13-21.
-
(2011)
Mitochondrion
, vol.11
, pp. 13-21
-
-
Tillement, L.1
Lecanu, L.2
Papadopoulos, V.3
-
253
-
-
84879251778
-
Structure of parkin reveals mechanisms for ubiquitin ligase activation
-
Trempe J-F, Sauvé V, Grenier K, Seirafi M, Tang MY, Ménade M, Al-Abdul-Wahid S, Krett J, Wong K, Kozlov G, et al., 2013. Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science 340: 1451-1455.
-
(2013)
Science
, vol.340
, pp. 1451-1455
-
-
Trempe, J.-F.1
Sauvé, V.2
Grenier, K.3
Seirafi, M.4
Tang, M.Y.5
Ménade, M.6
Al-Abdul-Wahid, S.7
Krett, J.8
Wong, K.9
Kozlov, G.10
-
254
-
-
84938651909
-
Antagonistic pleiotropic effects of nitric oxide in the pathophysiology of Parkinson's disease
-
Tripathy D, Chakraborty J, Mohanakumar KP., 2015. Antagonistic pleiotropic effects of nitric oxide in the pathophysiology of Parkinson's disease. Free Radic Res 49: 1129-1139.
-
(2015)
Free Radic Res
, vol.49
, pp. 1129-1139
-
-
Tripathy, D.1
Chakraborty, J.2
Mohanakumar, K.P.3
-
255
-
-
84895904175
-
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease
-
Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, et al., 2014. Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease. Nat Cell Biol 16: 157-166.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 157-166
-
-
Tufi, R.1
Gandhi, S.2
De Castro, I.P.3
Lehmann, S.4
Angelova, P.R.5
Dinsdale, D.6
Deas, E.7
Plun-Favreau, H.8
Nicotera, P.9
Abramov, A.Y.10
-
256
-
-
84947024027
-
Caffeine prevents D-galactose-induced cognitive deficits, oxidative stress, neuroinflammation and neurodegeneration in the adult rat brain
-
Ullah F, Ali T, Ullah N, Kim MO., 2015. Caffeine prevents D-galactose-induced cognitive deficits, oxidative stress, neuroinflammation and neurodegeneration in the adult rat brain. Neurochem Int 90: 114-124.
-
(2015)
Neurochem Int
, vol.90
, pp. 114-124
-
-
Ullah, F.1
Ali, T.2
Ullah, N.3
Kim, M.O.4
-
257
-
-
84949034084
-
The final countdown
-
Underwood E., 2015. The final countdown. Science 350: 1188-1190.
-
(2015)
Science
, vol.350
, pp. 1188-1190
-
-
Underwood, E.1
-
258
-
-
84868701486
-
Approaches toward new Alzheimer's treatments
-
Vacca JP., 2012. Approaches toward new Alzheimer's treatments. ACS Med Chem Lett 3: 861.
-
(2012)
ACS Med Chem Lett
, vol.3
, pp. 861
-
-
Vacca, J.P.1
-
259
-
-
84925134208
-
The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: A review
-
Vahid F, Zanda H, Nosrat-Mirshekarlou E, Najafi R, Hekmatdoost A., 2015. The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: a review. Gene 562: 8-15.
-
(2015)
Gene
, vol.562
, pp. 8-15
-
-
Vahid, F.1
Zanda, H.2
Nosrat-Mirshekarlou, E.3
Najafi, R.4
Hekmatdoost, A.5
-
260
-
-
0037362060
-
Lipoic acid induces p27Kip-dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines
-
van de Mark K, Chen JS, Steliou K, Perrine SP, Faller DV., 2003. α- Lipoic acid induces p27Kip-dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines. J Cell Physiol 194: 325-340.
-
(2003)
J Cell Physiol
, vol.194
, pp. 325-340
-
-
Van De Mark, K.1
Chen, J.S.2
Steliou, K.3
Perrine, S.P.4
Faller, D.V.5
-
261
-
-
84945156273
-
Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease
-
Villegas-Llerena C, Phillips A, Garcia-Reitboeck P, Hardy J, Pocock JM., 2016. Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease. Curr Opin Neurobiol 36: 74-81.
-
(2016)
Curr Opin Neurobiol
, vol.36
, pp. 74-81
-
-
Villegas-Llerena, C.1
Phillips, A.2
Garcia-Reitboeck, P.3
Hardy, J.4
Pocock, J.M.5
-
262
-
-
84921895084
-
Emerging Concepts in Alzheimer's Disease
-
Vinters HV., 2015. Emerging Concepts in Alzheimer's Disease. Annu Rev Pathol Mech Dis 10: 291-319.
-
(2015)
Annu Rev Pathol Mech Dis
, vol.10
, pp. 291-319
-
-
Vinters, H.V.1
-
263
-
-
84922739209
-
Histone deacetylases (HDACs) and brain function
-
Volmar C-H, Wahlestedt C., 2015. Histone deacetylases (HDACs) and brain function. Neuroepigenetics 1: 20-27.
-
(2015)
Neuroepigenetics
, vol.1
, pp. 20-27
-
-
Volmar, C.-H.1
Wahlestedt, C.2
-
264
-
-
84947339771
-
Alzheimer's disease biomarker states
-
Vos SJB, Fagan AM., 2016. Alzheimer's disease biomarker states. Lancet Neurol 15: 25-26.
-
(2016)
Lancet Neurol
, vol.15
, pp. 25-26
-
-
Vos, S.J.B.1
Fagan, A.M.2
-
265
-
-
84886259329
-
Small molecule inhibitors of zinc-dependent histone deacetylases
-
Wagner FF, Weïwer M, Lewis MC, Holson EB., 2013. Small molecule inhibitors of zinc-dependent histone deacetylases. Neurotherapeutics 10: 589-604.
-
(2013)
Neurotherapeutics
, vol.10
, pp. 589-604
-
-
Wagner, F.F.1
Weïwer, M.2
Lewis, M.C.3
Holson, E.B.4
-
266
-
-
84875868055
-
A mitochondrial bioenergetic etiology of disease
-
Wallace DC., 2013. A mitochondrial bioenergetic etiology of disease. J Clin Invest 123: 1405-1412.
-
(2013)
J Clin Invest
, vol.123
, pp. 1405-1412
-
-
Wallace, D.C.1
-
267
-
-
84904322386
-
Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients
-
Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB., 2014. Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proc Natl Acad Sci USA 111: 10323-10328.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 10323-10328
-
-
Watts, J.C.1
Condello, C.2
Stöhr, J.3
Oehler, A.4
Lee, J.5
DeArmond, S.J.6
Lannfelt, L.7
Ingelsson, M.8
Giles, K.9
Prusiner, S.B.10
-
268
-
-
84940722108
-
Selective removal of mitochondria via mitophagy: Distinct pathways for different mitochondrial stresses
-
Wei H, Liu L, Chen Q., 2015. Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses. BBA-Mol Cell Res 1853: 2784-2790.
-
(2015)
BBA-Mol Cell Res
, vol.1853
, pp. 2784-2790
-
-
Wei, H.1
Liu, L.2
Chen, Q.3
-
269
-
-
84927954285
-
Differential diagnosis of Mendelian and mitochondrial disorders in patients with suspected multiple sclerosis
-
Weisfeld-Adams JD, Sand IBK, Honce JM, Lublin FD., 2015. Differential diagnosis of Mendelian and mitochondrial disorders in patients with suspected multiple sclerosis. Brain 138: 517-539.
-
(2015)
Brain
, vol.138
, pp. 517-539
-
-
Weisfeld-Adams, J.D.1
Sand, I.B.K.2
Honce, J.M.3
Lublin, F.D.4
-
270
-
-
79955979595
-
Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice
-
Wiley JC, Pettan-Brewer C, Ladiges WC., 2011. Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice. Aging Cell 10: 418-428.
-
(2011)
Aging Cell
, vol.10
, pp. 418-428
-
-
Wiley, J.C.1
Pettan-Brewer, C.2
Ladiges, W.C.3
-
271
-
-
77949335521
-
The worldwide societal costs of dementia: Estimates for 2009
-
Wimo A, Winblad B, Jönsson L., 2010. The worldwide societal costs of dementia: estimates for 2009. Alzheimer's Dement 6: 98-103.
-
(2010)
Alzheimer's Dement
, vol.6
, pp. 98-103
-
-
Wimo, A.1
Winblad, B.2
Jönsson, L.3
-
272
-
-
84925279976
-
Immunotherapeutic approaches for Alzheimer's disease
-
Wisniewski T, Goñi F., 2015. Immunotherapeutic approaches for Alzheimer's disease. Neuron 85: 1162-1176.
-
(2015)
Neuron
, vol.85
, pp. 1162-1176
-
-
Wisniewski, T.1
Goñi, F.2
-
273
-
-
84939969420
-
Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers
-
Woo JA, Zhao X, Khan H, Penn C, Wang X, Joly-Amado A, Weeber E, Morgan D, Kang DE., 2015. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Nat Cell Differ 22: 921-934.
-
(2015)
Nat Cell Differ
, vol.22
, pp. 921-934
-
-
Woo, J.A.1
Zhao, X.2
Khan, H.3
Penn, C.4
Wang, X.5
Joly-Amado, A.6
Weeber, E.7
Morgan, D.8
Kang, D.E.9
-
274
-
-
84965189418
-
Dementia in western Europe: Epidemiological evidence and implications for policy making
-
Wu Y-T, Fratiglioni L, Matthews FE, Lobo A, Breteler MMB, Skoog I, Brayne C., 2016. Dementia in western Europe: epidemiological evidence and implications for policy making. Lancet Neuro 15: 116-124.
-
(2016)
Lancet Neuro
, vol.15
, pp. 116-124
-
-
Wu, Y.-T.1
Fratiglioni, L.2
Matthews, F.E.3
Lobo, A.4
Breteler, M.M.B.5
Skoog, I.6
Brayne, C.7
-
275
-
-
84920911585
-
Biomarkers in the diagnosis and management of Alzheimer's disease
-
Wurtman R., 2015. Biomarkers in the diagnosis and management of Alzheimer's disease. Metabolism 64: S47-S50.
-
(2015)
Metabolism
, vol.64
, pp. S47-S50
-
-
Wurtman, R.1
-
276
-
-
84924262484
-
Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease
-
Xia D, Watanabe H, Wu B, Lee SH, Li Y, Tsvetkov E, Bolshakov VY, Shen J, Kelleher RJ III., 2015. Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease. Neuron 85: 967-981.
-
(2015)
Neuron
, vol.85
, pp. 967-981
-
-
Xia, D.1
Watanabe, H.2
Wu, B.3
Lee, S.H.4
Li, Y.5
Tsvetkov, E.6
Bolshakov, V.Y.7
Shen, J.8
Kelleher, R.J.9
-
277
-
-
84935900032
-
Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease
-
Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, et al., 2014. Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. PLoS Biol 12: e1001923.
-
(2014)
PLoS Biol
, vol.12
, pp. e1001923
-
-
Xu, J.1
Chatterjee, M.2
Baguley, T.D.3
Brouillette, J.4
Kurup, P.5
Ghosh, D.6
Kanyo, J.7
Zhang, Y.8
Seyb, K.9
Ononenyi, C.10
-
278
-
-
84865544952
-
Mitochondrial fission, fusion and stress
-
Youle RJ, van der Bliek A., 2012. Mitochondrial fission, fusion and stress. Science 337: 1062-1065.
-
(2012)
Science
, vol.337
, pp. 1062-1065
-
-
Youle, R.J.1
Van Der Bliek, A.2
-
279
-
-
77649163840
-
Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice
-
Yu S, Khor TO, Cheung K-L, Li W, Wu T-Y, Huang Y, Foster BA, Kan YW, Kong A-N., 2010. Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice. PLoS One 5: e8579.
-
(2010)
PLoS One
, vol.5
, pp. e8579
-
-
Yu, S.1
Khor, T.O.2
Cheung, K.-L.3
Li, W.4
Wu, T.-Y.5
Huang, Y.6
Foster, B.A.7
Kan, Y.W.8
Kong, A.-N.9
-
280
-
-
80755133485
-
Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
-
Zachar Z, Marecek J, Maturo C, Gupta S, Stuart SD, Howell K, Schauble A, Lem J, Piramzadian A, Karnik S, et al., 2011. Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo. J Mol Med 89: 1137-1148.
-
(2011)
J Mol Med
, vol.89
, pp. 1137-1148
-
-
Zachar, Z.1
Marecek, J.2
Maturo, C.3
Gupta, S.4
Stuart, S.D.5
Howell, K.6
Schauble, A.7
Lem, J.8
Piramzadian, A.9
Karnik, S.10
-
281
-
-
80053943300
-
Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy
-
Zaitone SA, Abo-Elmatty DM, Shaalan AA., 2012. Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy. Pharmacol Biochem Behav 100: 347-360.
-
(2012)
Pharmacol Biochem Behav
, vol.100
, pp. 347-360
-
-
Zaitone, S.A.1
Abo-Elmatty, D.M.2
Shaalan, A.A.3
-
282
-
-
84926408980
-
A new regulatory mechanism for bacterial lipoic acid synthesis
-
Zhang H, Luo Q, Gao H, Feng Y., 2015. A new regulatory mechanism for bacterial lipoic acid synthesis. MicrobiologyOpen 4: 282-300.
-
(2015)
MicrobiologyOpen
, vol.4
, pp. 282-300
-
-
Zhang, H.1
Luo, Q.2
Gao, H.3
Feng, Y.4
-
283
-
-
84905384868
-
Pink1, the first ubiquitin kinase
-
Zheng X, Hunter T., 2014. Pink1, the first ubiquitin kinase. EMBO J. 33: 1621-1623.
-
(2014)
EMBO J.
, vol.33
, pp. 1621-1623
-
-
Zheng, X.1
Hunter, T.2
|