-
1
-
-
84902593115
-
New drug development-Alzheimer disease
-
Apter JT. New drug development-Alzheimer disease. Neuropsychopharmacology 1994;11:264.
-
(1994)
Neuropsychopharmacology
, vol.11
, pp. 264
-
-
Apter, J.T.1
-
2
-
-
84872343747
-
Folate and Alzheimer: When time matters
-
Hinterberger M, Fischer P. Folate and Alzheimer: When time matters. J Neural Transm 2013;120:211-224.
-
(2013)
J Neural Transm
, vol.120
, pp. 211-224
-
-
Hinterberger, M.1
Fischer, P.2
-
3
-
-
83355173051
-
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
-
Chen Q, Prior M, Dargusch R, Roberts A, Riek R, Eichmann C, Chiruta C, Akaishi T, Abe K, Maher P, Schubert D. A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. PLoS One 2011;6:e27865.
-
(2011)
PLoS One
, vol.6
-
-
Chen, Q.1
Prior, M.2
Dargusch, R.3
Roberts, A.4
Riek, R.5
Eichmann, C.6
Chiruta, C.7
Akaishi, T.8
Abe, K.9
Maher, P.10
Schubert, D.11
-
4
-
-
84889590775
-
Nature of the neurotoxic membrane actions of amyloid-beta on hippocampal neurons in Alzheimer's disease
-
Sepulveda FJ, Fierro H, Fernandez E, Castillo C, Peoples RW, Opazo C, Aguayo LG. Nature of the neurotoxic membrane actions of amyloid-beta on hippocampal neurons in Alzheimer's disease. Neurobiol Aging 2014;35:472-481.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 472-481
-
-
Sepulveda, F.J.1
Fierro, H.2
Fernandez, E.3
Castillo, C.4
Peoples, R.W.5
Opazo, C.6
Aguayo, L.G.7
-
5
-
-
34547147090
-
The redox chemistry of the Alzheimer's disease amyloid βpeptide
-
DOI 10.1016/j.bbamem.2007.02.002, PII S0005273607000387
-
Smith DG, Cappai R, Barnham KJ. The redox chemistry of the Alzheimer's disease amyloid beta peptide. Biochim Biophys Acta 2007;1768:1976-1990. (Pubitemid 47125850)
-
(2007)
Biochimica et Biophysica Acta - Biomembranes
, vol.1768
, Issue.8
, pp. 1976-1990
-
-
Smith, D.G.1
Cappai, R.2
Barnham, K.J.3
-
6
-
-
84889596911
-
Betaamyloid impairs the regulation of N-methyl-D-aspartate receptors by glycogen synthase kinase 3
-
Deng, Y., Xiong Z, Chen P, Wei J, Chen S, Yan Z. Betaamyloid impairs the regulation of N-methyl-D-aspartate receptors by glycogen synthase kinase 3. Neurobiol Aging 2014;35:449-459.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 449-459
-
-
Deng, Y.1
Xiong, Z.2
Chen, P.3
Wei, J.4
Chen, S.5
Yan, Z.6
-
7
-
-
84873722112
-
Bis(9)-(-)-normeptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice
-
Liu T, Xia Z, Zhang WW, Xu JR, Ge XX, Li J, Cui Y, Qiu ZB, Xu J, Xie Q, Wang H, Chen HZ. Bis(9)-(-)-normeptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice. Pharmacol Biochem Behav 2013;104:138-143.
-
(2013)
Pharmacol Biochem Behav
, vol.104
, pp. 138-143
-
-
Liu, T.1
Xia, Z.2
Zhang, W.W.3
Xu, J.R.4
Ge, X.X.5
Li, J.6
Cui, Y.7
Qiu, Z.B.8
Xu, J.9
Xie, Q.10
Wang, H.11
Chen, H.Z.12
-
8
-
-
84866240546
-
Supplementation of Convolvulus pluricaulis attenuates scopolamine-induced increased tau and amyloid precursor protein (AbetaPP) expression in rat brain
-
Bihaqi SW, Singh AP, Tiwari M. Supplementation of Convolvulus pluricaulis attenuates scopolamine-induced increased tau and amyloid precursor protein (AbetaPP) expression in rat brain. Indian J Pharmacol 2012;44:593-598.
-
(2012)
Indian J Pharmacol
, vol.44
, pp. 593-598
-
-
Bihaqi, S.W.1
Singh, A.P.2
Tiwari, M.3
-
9
-
-
84864954221
-
Attenuation of scopolamine-induced cognitive dysfunction by obovatol
-
Choi DY, Lee YJ, Lee SY, Lee YM, Lee HH, Choi IS, Oh KW, Han SB, Nam SY, Hong JT. Attenuation of scopolamine-induced cognitive dysfunction by obovatol. Arch Pharm Res 2012;35:1279-1286.
-
(2012)
Arch Pharm Res
, vol.35
, pp. 1279-1286
-
-
Choi, D.Y.1
Lee, Y.J.2
Lee, S.Y.3
Lee, Y.M.4
Lee, H.H.5
Choi, I.S.6
Oh, K.W.7
Han, S.B.8
Nam, S.Y.9
Hong, J.T.10
-
10
-
-
83555161656
-
Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: A behavioral, biochemical and cerebral blood flow study
-
Pachauri SD, Tota S, Khandelwal K, Verma PR, Nath C, Hanif K, Shukla R, Saxena JK, Dwivedi AK. Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: A behavioral, biochemical and cerebral blood flow study. J Ethnopharmacol 2012;139:34-41.
-
(2012)
J Ethnopharmacol
, vol.139
, pp. 34-41
-
-
Pachauri, S.D.1
Tota, S.2
Khandelwal, K.3
Verma, P.R.4
Nath, C.5
Hanif, K.6
Shukla, R.7
Saxena, J.K.8
Dwivedi, A.K.9
-
11
-
-
84872501370
-
Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway
-
Wang X, Wang ZH, Wu YY, Tang H, Tan L, Wang X, Gao XY, Xiong YS, Liu D, Wang JZ, Zhu LQ. Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway. Mol Neurobiol 2013;47:373-381.
-
(2013)
Mol Neurobiol
, vol.47
, pp. 373-381
-
-
Wang, X.1
Wang, Z.H.2
Wu, Y.Y.3
Tang, H.4
Tan, L.5
Wang, X.6
Gao, X.Y.7
Xiong, Y.S.8
Liu, D.9
Wang, J.Z.10
Zhu, L.Q.11
-
12
-
-
84874153672
-
Pharmacological characterization of memoquin, a multi-target compound for the treatment of Alzheimer's disease
-
Capurro V, Busquet P, Lopes JP, Bertorelli R, Tarozzo G, Bolognesi ML, Piomelli D, Reggiani A, Cavalli A. Pharmacological characterization of memoquin, a multi-target compound for the treatment of Alzheimer's disease. PLoS One 2013;8:e56870.
-
(2013)
PLoS One
, vol.8
-
-
Capurro, V.1
Busquet, P.2
Lopes, J.P.3
Bertorelli, R.4
Tarozzo, G.5
Bolognesi, M.L.6
Piomelli, D.7
Reggiani, A.8
Cavalli, A.9
-
13
-
-
84858112837
-
Studies on effects of Emblica officinalis (Amla) on oxidative stress and cholinergic function in scopolamine induced amnesia in mice
-
Golechha M, Bhatia J, Arya DS. Studies on effects of Emblica officinalis (Amla) on oxidative stress and cholinergic function in scopolamine induced amnesia in mice. J Environ Biol 2012;33:95-100.
-
(2012)
J Environ Biol
, vol.33
, pp. 95-100
-
-
Golechha, M.1
Bhatia, J.2
Arya, D.S.3
-
14
-
-
84875647455
-
7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways
-
Tsai T, Klausmeyer A, Conrad R, Gottschling C, Leo M, Faissner A, Wiese S. 7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways. Mol Cell Neurosci 2013; 56C:18-28.
-
(2013)
Mol Cell Neurosci
, vol.56 C
, pp. 18-28
-
-
Tsai, T.1
Klausmeyer, A.2
Conrad, R.3
Gottschling, C.4
Leo, M.5
Faissner, A.6
Wiese, S.7
-
15
-
-
84864124228
-
7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats
-
Zeng Y, Lv F, Li L, Yu H, Dong M, Fu Q. 7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats. J Neurochem 2012;122:800-811.
-
(2012)
J Neurochem
, vol.122
, pp. 800-811
-
-
Zeng, Y.1
Lv, F.2
Li, L.3
Yu, H.4
Dong, M.5
Fu, Q.6
-
16
-
-
84886598792
-
Acetyl-L-carnitine rescues scopolamine-induced memory deficits by restoring insulin-like growth factor II via decreasing p53 oxidation
-
Wang X, Wang LP, Tang H, Shan WY, Wang X, Liu D, Wu YY, Tian Q, Wang JZ, Zhu LQ. Acetyl-L-carnitine rescues scopolamine-induced memory deficits by restoring insulin-like growth factor II via decreasing p53 oxidation. Neuropharmacology 2014;76(ptA):80-87.
-
(2014)
Neuropharmacology
, vol.76
, Issue.PART A
, pp. 80-87
-
-
Wang, X.1
Wang, L.P.2
Tang, H.3
Shan, W.Y.4
Wang, X.5
Liu, D.6
Wu, Y.Y.7
Tian, Q.8
Wang, J.Z.9
Zhu, L.Q.10
-
17
-
-
84879763913
-
The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease
-
Rantamaki T, Kemppainen S, Autio H, Stavén S, Koivisto H, Kojima M, Antila H, Miettinen PO, Kärkkäinen E, Karpova N, Vesa L, Lindemann L, Hoener MC, Tanila H, Castrén E. The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease. PLoS One 2013;8:e68722.
-
(2013)
PLoS One
, vol.8
-
-
Rantamaki, T.1
Kemppainen, S.2
Autio, H.3
Stavén, S.4
Koivisto, H.5
Kojima, M.6
Antila, H.7
Miettinen, P.O.8
Kärkkäinen, E.9
Karpova, N.10
Vesa, L.11
Lindemann, L.12
Hoener, M.C.13
Tanila, H.14
Castrén, E.15
-
18
-
-
77249168715
-
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
-
Jang SW, Liu X, Yepes M, Shepherd KR, Miller GW, Liu Y, Wilson WD, Xiao G, Blanchi B, Sun YE, Ye K. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proc Natl Acad Sci USA 2010; 107:2687-2692.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2687-2692
-
-
Jang, S.W.1
Liu, X.2
Yepes, M.3
Shepherd, K.R.4
Miller, G.W.5
Liu, Y.6
Wilson, W.D.7
Xiao, G.8
Blanchi, B.9
Sun, Y.E.10
Ye, K.11
-
19
-
-
84885102754
-
7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice
-
Bollen E, Vanmierlo T, Akkerman S, Wouters C, Steinbusch HM, Prickaerts J. 7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice. Behav Brain Res 2013;257C:8-12.
-
(2013)
Behav Brain Res
, vol.257 C
, pp. 8-12
-
-
Bollen, E.1
Vanmierlo, T.2
Akkerman, S.3
Wouters, C.4
Steinbusch, H.M.5
Prickaerts, J.6
-
20
-
-
84890442031
-
BDNF-induced local protein synthesis and synaptic plasticity
-
Leal G, Comprido D, Duarte CB. BDNF-induced local protein synthesis and synaptic plasticity. Neuropharmacology 2014;76(Pt C):639-656.
-
(2014)
Neuropharmacology
, vol.76
, Issue.PART C
, pp. 639-656
-
-
Leal, G.1
Comprido, D.2
Duarte, C.B.3
-
21
-
-
33846903377
-
Role of neurotrophic factors in depression
-
DOI 10.1016/j.coph.2006.08.009, PII S1471489206001718, Neurosciences
-
Castren E, Voikar V, Rantamaki T. Role of neurotrophic factors in depression. Curr Opin Pharmacol 2007;7:18-21. (Pubitemid 46238033)
-
(2007)
Current Opinion in Pharmacology
, vol.7
, Issue.1
, pp. 18-21
-
-
Castren, E.1
Voikar, V.2
Rantamaki, T.3
-
22
-
-
84874114021
-
Ginsenosides Rg5 and Rh3 protect scopolamine-induced memory deficits in mice
-
Kim EJ, Jung IH, Van Le TK, Jeong JJ, Kim NJ, Kim DH. Ginsenosides Rg5 and Rh3 protect scopolamine-induced memory deficits in mice. J Ethnopharmacol 2013;146:294-299.
-
(2013)
J Ethnopharmacol
, vol.146
, pp. 294-299
-
-
Kim, E.J.1
Jung, I.H.2
Van Le, T.K.3
Jeong, J.J.4
Kim, N.J.5
Kim, D.H.6
-
23
-
-
84872724945
-
Angelica keiskei ameliorates scopolamine-induced memory impairments in mice
-
Oh, S.R., Kim SJ, Kim DH, Ryu JH, Ahn EM, Jung JW. Angelica keiskei ameliorates scopolamine-induced memory impairments in mice. Biol Pharm Bull 2013;36:82-88.
-
(2013)
Biol Pharm Bull
, vol.36
, pp. 82-88
-
-
Oh, S.R.1
Kim, S.J.2
Kim, D.H.3
Ryu, J.H.4
Ahn, E.M.5
Jung, J.W.6
-
24
-
-
0037219345
-
Phosphatidylinositol 3-kinase: A molecule mediating BDNF-dependent spatial memory formation
-
DOI 10.1038/sj.mp.4001215
-
Mizuno M, Yamada K, Takei N, Tran MH, He J, Nakajima A, Nawa H, Nabeshima T. Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation. Mol Psychiatry 2003;8:217-224. (Pubitemid 36315230)
-
(2003)
Molecular Psychiatry
, vol.8
, Issue.2
, pp. 217-224
-
-
Mizuno, M.1
Yamada, K.2
Takei, N.3
Tran, M.H.4
He, J.5
Nakajima, A.6
Nawa, H.7
Nabeshima, T.8
-
25
-
-
84878791565
-
Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat
-
Zhang L, Zhao H, Zhang X, Chen L, Zhao X, Bai X, Zhang J. Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat. Brain Res Bull 2013; 96:45-53.
-
(2013)
Brain Res Bull
, vol.96
, pp. 45-53
-
-
Zhang, L.1
Zhao, H.2
Zhang, X.3
Chen, L.4
Zhao, X.5
Bai, X.6
Zhang, J.7
-
26
-
-
84875977924
-
Alzheimer's phenotypes induced by overexpression of human presenilin 2 mutant proteins stimulate significant changes in key factors of glucose metabolism
-
Lee YJ, Kim JE, Hwang IS, Kwak MH, Lee JH, Jung YJ, An BS, Kwon HS, Kim BC, Kim SJ, Kim JM, Hwang DY. Alzheimer's phenotypes induced by overexpression of human presenilin 2 mutant proteins stimulate significant changes in key factors of glucose metabolism. Mol Med Rep 2013;7:1571-1578.
-
(2013)
Mol Med Rep
, vol.7
, pp. 1571-1578
-
-
Lee, Y.J.1
Kim, J.E.2
Hwang, I.S.3
Kwak, M.H.4
Lee, J.H.5
Jung, Y.J.6
An, B.S.7
Kwon, H.S.8
Kim, B.C.9
Kim, S.J.10
Kim, J.M.11
Hwang, D.Y.12
-
27
-
-
84857039173
-
Agmatine protects against scopolamine-induced water maze performance impairment and hippocampal ERK and Akt inactivation
-
Moosavi M, Khales GY, Abbasi L, Zarifkar A, Rastegar K. Agmatine protects against scopolamine-induced water maze performance impairment and hippocampal ERK and Akt inactivation. Neuropharmacology 2012;62:2018-2023.
-
(2012)
Neuropharmacology
, vol.62
, pp. 2018-2023
-
-
Moosavi, M.1
Khales, G.Y.2
Abbasi, L.3
Zarifkar, A.4
Rastegar, K.5
-
28
-
-
84885461983
-
Neuroprotective role of a novel copper chelator against Abeta 42 induced neurotoxicity
-
Singh SK, Sinha P, Mishra L, Srikrishna S. Neuroprotective role of a novel copper chelator against Abeta 42 induced neurotoxicity. Int J Alzheimers Dis 2013;2013:567128.
-
(2013)
Int J Alzheimers Dis
, vol.2013
, pp. 567128
-
-
Singh, S.K.1
Sinha, P.2
Mishra, L.3
Srikrishna, S.4
|