α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 3, 2015, Pages 273-281

  Fernández Galilea, Marta ^a,g   Pérez Matute, Patricia ^b   Prieto Hontoria, Pedro L ^a,c   Houssier, Marianne ^d   Burrell, María A ^a   Langin, Dominique ^d,e   Martínez, J Alfredo ^a,f   Moreno Aliaga, María J ^a,f  

^a UNIVERSITY OF NAVARRA   (Spain)

^b CENTER FOR BIOMEDICAL RESEARCH OF LA RIOJA CIBIR   (Spain)

^c Facultad de Estudios del Patrimonio Cultural   (Chile)

^d University Hospital of Toulouse   (France)

^e TOULOUSE UNIVERSITY HOSPITAL   (France)

^f Instituto de Salud Carlos III   (Spain)

^g PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Brown adipose tissue; Human adipocyte; Mitochondrial biogenesis; Obesity; Lipoic acid

Indexed keywords

ACYL COENZYME A OXIDASE; CARNITINE PALMITOYLTRANSFERASE I; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF1; UNCOUPLING PROTEIN 1; ACOX2 PROTEIN, HUMAN; ANTIOXIDANT; APOPTOSIS REGULATORY PROTEIN; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A, HUMAN; CIDEA PROTEIN, HUMAN; DNA BINDING PROTEIN; MITOCHONDRIAL PROTEIN; NRF1 PROTEIN, HUMAN; NUCLEAR RESPIRATORY FACTOR 1; OXIDOREDUCTASE; PPARGC1A PROTEIN, HUMAN; PRDM16 PROTEIN, HUMAN; SIRT1 PROTEIN, HUMAN; T BOX TRANSCRIPTION FACTOR; TBX1 PROTEIN, HUMAN; TFAM PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADIPOCYTE; ARTICLE; BIOGENESIS; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FATTY ACID METABOLISM; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; MITOCHONDRION; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SUBCUTANEOUS FAT; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; ACETYLATION; AGONISTS; BROWN ADIPOCYTE; CELL DIFFERENTIATION; COPY NUMBER VARIATION; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRIAL DYNAMICS; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ACETYLATION; ADIPOCYTES, BROWN; ANTIOXIDANTS; APOPTOSIS REGULATORY PROTEINS; CARNITINE O-PALMITOYLTRANSFERASE; CELL DIFFERENTIATION; DNA COPY NUMBER VARIATIONS; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MITOCHONDRIAL TURNOVER; NUCLEAR RESPIRATORY FACTOR 1; OBESITY; OXIDOREDUCTASES; OXYGEN CONSUMPTION; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; SIRTUIN 1; SUBCUTANEOUS FAT; T-BOX DOMAIN PROTEINS; THIOCTIC ACID; TRANSCRIPTION FACTORS;

EID: 84920771529     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.12.013     Document Type: Article

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