Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex i inhibition

Drug Development Research

Volumn 76, Issue 2, 2015, Pages 72-81

  Parameshwaran, Kodeeswaran ^a,e   Irwin, Michael H ^a   Steliou, Kosta ^b,f   Suppiramaniam, Vishnu ^c   Pinkert, Carl A ^a,d  

^a AUBURN UNIVERSITY   (United States)

^b PhenoMatriX Inc   (United States)

^c AUBURN UNIVERSITY   (United States)

^d UNIVERSITY OF ALABAMA   (United States)

^e TEXAS A AND M UNIVERSITY COMMERCE   (United States)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

antioxidants; complex I; hippocampus; mitochondria; rotenone; synaptic physiology

Indexed keywords

ANTIOXIDANT; LIPOYLCARNITINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; UNCLASSIFIED DRUG; CARNITINE; PMX-500FI; THIOCTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOENERGY; BRAIN ELECTROPHYSIOLOGY; BRAIN REGION; BRAIN SLICE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HIPPOCAMPAL CA1 REGION; LONG TERM POTENTIATION; MEMORY; MOUSE; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATIVE STRESS; RESPIRATORY CHAIN; SYNAPTIC TRANSMISSION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ELECTROPHYSIOLOGY; HIPPOCAMPUS; INSTITUTE FOR CANCER RESEARCH MOUSE; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; CARNITINE; ELECTRON TRANSPORT COMPLEX I; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; HIPPOCAMPUS; LONG-TERM POTENTIATION; MICE; MICE, INBRED ICR; MODELS, ANIMAL; ROTENONE; SIGNAL TRANSDUCTION; THIOCTIC ACID;

EID: 84927758763     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.21242     Document Type: Article

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