-
1
-
-
80054765940
-
Bioenergetic consequences of PINK1 mutations in Parkinson disease
-
A.Y. Abramov, M. Gegg, A. Grunewald, N.W. Wood, C. Klein, and A.H. Schapira Bioenergetic consequences of PINK1 mutations in Parkinson disease PLoS ONE 6 2011 e25622
-
(2011)
PLoS ONE
, vol.6
, pp. 25622
-
-
Abramov, A.Y.1
Gegg, M.2
Grunewald, A.3
Wood, N.W.4
Klein, C.5
Schapira, A.H.6
-
2
-
-
84889100159
-
Loss of iron triggers PINK1/Parkin-independent mitophagy
-
G.F. Allen, R. Toth, J. James, and I.G. Ganley Loss of iron triggers PINK1/Parkin-independent mitophagy EMBO Rep 14 2013 1127 1135
-
(2013)
EMBO Rep
, vol.14
, pp. 1127-1135
-
-
Allen, G.F.1
Toth, R.2
James, J.3
Ganley, I.G.4
-
3
-
-
84913546616
-
Mitophagy is required for acute cardioprotection by simvastatin
-
[Epub ahead of print]
-
A.M. Andres, G. Hernandez, P. Lee, C. Huang, E.P. Ratliff, and J. Sin et al. Mitophagy is required for acute cardioprotection by simvastatin Antioxid Redox Signal 2013 [Epub ahead of print]
-
(2013)
Antioxid Redox Signal
-
-
Andres, A.M.1
Hernandez, G.2
Lee, P.3
Huang, C.4
Ratliff, E.P.5
Sin, J.6
-
4
-
-
80052197610
-
Phosphorylation of Ser114 on Atg32 mediates mitophagy
-
Y. Aoki, T. Kanki, Y. Hirota, Y. Kurihara, T. Saigusa, and T. Uchiumi et al. Phosphorylation of Ser114 on Atg32 mediates mitophagy Mol Biol Cell 2011
-
(2011)
Mol Biol Cell
-
-
Aoki, Y.1
Kanki, T.2
Hirota, Y.3
Kurihara, Y.4
Saigusa, T.5
Uchiumi, T.6
-
5
-
-
78650006375
-
PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells
-
A. Berthier, S. Navarro, J. Jimenez-Sainz, I. Rogla, F. Ripoll, and J. Cervera et al. PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells Hum Pathol 42 2011 75 87
-
(2011)
Hum Pathol
, vol.42
, pp. 75-87
-
-
Berthier, A.1
Navarro, S.2
Jimenez-Sainz, J.3
Rogla, I.4
Ripoll, F.5
Cervera, J.6
-
6
-
-
77949541314
-
High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer
-
A. Berthier, S. Seguin, A.J. Sasco, J.Y. Bobin, G. De Laroche, and J. Datchary et al. High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer Br J Cancer 102 2010 1024 1031
-
(2010)
Br J Cancer
, vol.102
, pp. 1024-1031
-
-
Berthier, A.1
Seguin, S.2
Sasco, A.J.3
Bobin, J.Y.4
De Laroche, G.5
Datchary, J.6
-
7
-
-
79959344616
-
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
-
F. Billia, L. Hauck, F. Konecny, V. Rao, J. Shen, and T.W. Mak PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function Proc Natl Acad Sci USA 108 2011 9572 9577
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9572-9577
-
-
Billia, F.1
Hauck, L.2
Konecny, F.3
Rao, V.4
Shen, J.5
Mak, T.W.6
-
8
-
-
84883462430
-
The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy
-
V.S. Burchell, D.E. Nelson, A. Sanchez-Martinez, M. gado-Camprubi, R.M. Ivatt, and J.H. Pogson et al. The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy Nat Neurosci 16 2013 1257 1265
-
(2013)
Nat Neurosci
, vol.16
, pp. 1257-1265
-
-
Burchell, V.S.1
Nelson, D.E.2
Sanchez-Martinez, A.3
Gado-Camprubi, M.4
Ivatt, R.M.5
Pogson, J.H.6
-
9
-
-
84858701257
-
Spatial Parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons
-
Q. Cai, H.M. Zakaria, A. Simone, and Z.H. Sheng Spatial Parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons Curr Biol 22 2012 545 552
-
(2012)
Curr Biol
, vol.22
, pp. 545-552
-
-
Cai, Q.1
Zakaria, H.M.2
Simone, A.3
Sheng, Z.H.4
-
10
-
-
34848881905
-
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma
-
DOI 10.1172/JCI31457
-
D.F. Calvisi, S. Ladu, A. Gorden, M. Farina, J.S. Lee, and E.A. Conner et al. Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma J Clin Invest 117 2007 2713 2722 (Pubitemid 47494371)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.9
, pp. 2713-2722
-
-
Calvisi, D.F.1
Ladu, S.2
Gorden, A.3
Farina, M.4
Lee, J.-S.5
Conner, E.A.6
Schroeder, I.7
Factor, V.M.8
Thorgeirsson, S.S.9
-
11
-
-
77953728406
-
GABARAPL1 (GEC1) associates with autophagic vesicles
-
F.Z. Chakrama, S. Seguin-Py, J.N. Le Grand, A. Fraichard, R. age-Mourroux, and G. Despouy et al. GABARAPL1 (GEC1) associates with autophagic vesicles Autophagy 6 2010
-
(2010)
Autophagy
, vol.6
-
-
Chakrama, F.Z.1
Seguin-Py, S.2
Le Grand, J.N.3
Fraichard, A.4
Age-Mourroux, R.5
Despouy, G.6
-
12
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
-
N.C. Chan, A.M. Salazar, A.H. Pham, M.J. Sweredoski, N.J. Kolawa, and R.L. Graham et al. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy Hum Mol Genet 20 2011 1726 1737
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
-
13
-
-
84876531457
-
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
-
Y. Chen, and G.W. Dorn PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria Science 340 2013 471 475
-
(2013)
Science
, vol.340
, pp. 471-475
-
-
Chen, Y.1
Dorn, G.W.2
-
14
-
-
84885176082
-
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells 3
-
C.T. Chu, J. Ji, R.K. Dagda, J.F. Jiang, Y.Y. Tyurina, and A.A. Kapralov et al. Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells 3 Nat Cell Biol 15 2013 1197 1205
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1197-1205
-
-
Chu, C.T.1
Ji, J.2
Dagda, R.K.3
Jiang, J.F.4
Tyurina, Y.Y.5
Kapralov, A.A.6
-
15
-
-
61449137784
-
Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival
-
A. de Reynies, G. Assie, D.S. Rickman, F. Tissier, L. Groussin, and F. Rene-Corail et al. Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival J Clin Oncol 27 2009 1108 1115
-
(2009)
J Clin Oncol
, vol.27
, pp. 1108-1115
-
-
De Reynies, A.1
Assie, G.2
Rickman, D.S.3
Tissier, F.4
Groussin, L.5
Rene-Corail, F.6
-
16
-
-
84879047011
-
Cellular metabolic and autophagic pathways: Traffic control by redox signaling
-
M. Dodson, V. Darley-Usmar, and J. Zhang Cellular metabolic and autophagic pathways: traffic control by redox signaling Free Radic Biol Med 63 2013 207 221
-
(2013)
Free Radic Biol Med
, vol.63
, pp. 207-221
-
-
Dodson, M.1
Darley-Usmar, V.2
Zhang, J.3
-
17
-
-
77955514158
-
Mitochondrial pruning by Nix and BNip3: An essential function for cardiac-expressed death factors
-
G.W. Dorn Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factors J Cardiovasc Transl Res 3 2010 374 383
-
(2010)
J Cardiovasc Transl Res
, vol.3
, pp. 374-383
-
-
Dorn, G.W.1
-
18
-
-
84859896427
-
Contribution of impaired mitochondrial autophagy to cardiac aging: Mechanisms and therapeutic opportunities
-
D. Dutta, R. Calvani, R. Bernabei, C. Leeuwenburgh, and E. Marzetti Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities Circ Res 110 2012 1125 1138
-
(2012)
Circ Res
, vol.110
, pp. 1125-1138
-
-
Dutta, D.1
Calvani, R.2
Bernabei, R.3
Leeuwenburgh, C.4
Marzetti, E.5
-
19
-
-
33845976357
-
Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology
-
DOI 10.1074/jbc.M606059200
-
S. Duvezin-Caubet, R. Jagasia, J. Wagener, S. Hofmann, A. Trifunovic, and A. Hansson et al. Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology J Biol Chem 281 2006 37972 37979 (Pubitemid 46042101)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.49
, pp. 37972-37979
-
-
Duvezin-Caubet, S.1
Jagasia, R.2
Wagener, J.3
Hofmann, S.4
Trifunovic, A.5
Hansson, A.6
Chomyn, A.7
Bauer, M.F.8
Attardi, G.9
Larsson, N.-G.10
Neupert, W.11
Reichert, A.S.12
-
20
-
-
0035487007
-
The mitochondrial permeability transition initiates autophagy in rat hepatocytes
-
S.P. Elmore, T. Qian, S.F. Grissom, and J.J. Lemasters The mitochondrial permeability transition initiates autophagy in rat hepatocytes FASEB J 15 2001 2286 2287
-
(2001)
FASEB J
, vol.15
, pp. 2286-2287
-
-
Elmore, S.P.1
Qian, T.2
Grissom, S.F.3
Lemasters, J.J.4
-
21
-
-
21744434389
-
Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis
-
DOI 10.1038/sj.onc.1208642
-
M. Erkan, J. Kleeff, I. Esposito, T. Giese, K. Ketterer, and M.W. Buchler et al. Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis Oncogene 24 2005 4421 4432 (Pubitemid 40961765)
-
(2005)
Oncogene
, vol.24
, Issue.27
, pp. 4421-4432
-
-
Erkan, M.1
Kleeff, J.2
Esposito, I.3
Giese, T.4
Ketterer, K.5
Buchler, M.W.6
Giese, N.A.7
Friess, H.8
-
22
-
-
84055199656
-
Combined expression of BUB1B, DLGAP5, and PINK1 as predictors of poor outcome in adrenocortical tumors: Validation in a Brazilian cohort of adult and pediatric patients
-
M.C. Fragoso, M.Q. Almeida, T.L. Mazzuco, B.M. Mariani, L.P. Brito, and T.C. Goncalves et al. Combined expression of BUB1B, DLGAP5, and PINK1 as predictors of poor outcome in adrenocortical tumors: validation in a Brazilian cohort of adult and pediatric patients Eur J Endocrinol 166 2012 61 67
-
(2012)
Eur J Endocrinol
, vol.166
, pp. 61-67
-
-
Fragoso, M.C.1
Almeida, M.Q.2
Mazzuco, T.L.3
Mariani, B.M.4
Brito, L.P.5
Goncalves, T.C.6
-
23
-
-
0035487808
-
The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis
-
DOI 10.1016/S1534-5807(01)00055-7, PII S1534580701000557
-
S. Frank, B. Gaume, E.S. Bergmann-Leitner, W.W. Leitner, E.G. Robert, and F. Catez et al. The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis Dev Cell 1 2001 515 525 (Pubitemid 33586103)
-
(2001)
Developmental Cell
, vol.1
, Issue.4
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
24
-
-
53649108020
-
Parkin as a tumor suppressor gene for hepatocellular carcinoma
-
M. Fujiwara, H. Marusawa, H.Q. Wang, A. Iwai, K. Ikeuchi, and Y. Imai et al. Parkin as a tumor suppressor gene for hepatocellular carcinoma Oncogene 27 2008 6002 6011
-
(2008)
Oncogene
, vol.27
, pp. 6002-6011
-
-
Fujiwara, M.1
Marusawa, H.2
Wang, H.Q.3
Iwai, A.4
Ikeuchi, K.5
Imai, Y.6
-
25
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
M.E. Gegg, J.M. Cooper, K.Y. Chau, M. Rojo, A.H. Schapira, and J.W. Taanman Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin- dependent manner upon induction of mitophagy Hum Mol Genet 19 2010 4861 4870
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
26
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
S. Geisler, K.M. Holmstrom, D. Skujat, F.C. Fiesel, O.C. Rothfuss, and P.J. Kahle et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 Nat Cell Biol 12 2010 119 131
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
-
27
-
-
77957673363
-
The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
-
S. Geisler, K.M. Holmstrom, A. Treis, D. Skujat, S.S. Weber, and F.C. Fiesel et al. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations Autophagy 6 2010 871 878
-
(2010)
Autophagy
, vol.6
, pp. 871-878
-
-
Geisler, S.1
Holmstrom, K.M.2
Treis, A.3
Skujat, D.4
Weber, S.S.5
Fiesel, F.C.6
-
28
-
-
84856951239
-
Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition
-
R.W. Gilkerson, R.L. de Vries, P. Lebot, J.D. Wikstrom, E. Torgyekes, and O.S. Shirihai et al. Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition Hum Mol Genet 21 2012 978 990
-
(2012)
Hum Mol Genet
, vol.21
, pp. 978-990
-
-
Gilkerson, R.W.1
De Vries, R.L.2
Lebot, P.3
Wikstrom, J.D.4
Torgyekes, E.5
Shirihai, O.S.6
-
29
-
-
84864015441
-
BNip3 regulates mitochondrial function and lipid metabolism in the liver
-
D. Glick, W. Zhang, M. Beaton, G. Marsboom, M. Gruber, and M.C. Simon et al. BNip3 regulates mitochondrial function and lipid metabolism in the liver Mol Cell Biol 32 2012 2570 2584
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2570-2584
-
-
Glick, D.1
Zhang, W.2
Beaton, M.3
Marsboom, G.4
Gruber, M.5
Simon, M.C.6
-
30
-
-
84877014607
-
AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease
-
J. Haskin, R. Szargel, V. Shani, L.N. Mekies, R. Rott, and G.G. Lim et al. AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease Hum Mol Genet 22 2013 2083 2096
-
(2013)
Hum Mol Genet
, vol.22
, pp. 2083-2096
-
-
Haskin, J.1
Szargel, R.2
Shani, V.3
Mekies, L.N.4
Rott, R.5
Lim, G.G.6
-
31
-
-
84890429468
-
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
-
S.A. Hasson, L.A. Kane, K. Yamano, C.H. Huang, D.A. Sliter, and E. Buehler et al. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy Nature 504 2013 291 295
-
(2013)
Nature
, vol.504
, pp. 291-295
-
-
Hasson, S.A.1
Kane, L.A.2
Yamano, K.3
Huang, C.H.4
Sliter, D.A.5
Buehler, E.6
-
32
-
-
84859475104
-
Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: The protective role of autophagy
-
A.N. Higdon, G.A. Benavides, B.K. Chacko, X. Ouyang, M.S. Johnson, and A. Landar et al. Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy Am J Physiol Heart Circ Physiol 302 2012 H1394 H1409
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
-
-
Higdon, A.N.1
Benavides, G.A.2
Chacko, B.K.3
Ouyang, X.4
Johnson, M.S.5
Landar, A.6
-
33
-
-
84869388804
-
Integration of cellular bioenergetics with mitochondrial quality control and autophagy
-
B.G. Hill, G.A. Benavides, J.R. Lancaster Jr., S. Ballinger, L. Dell'italia, and J. Zhang et al. Integration of cellular bioenergetics with mitochondrial quality control and autophagy Biol Chem 393 2012 1485 1512
-
(2012)
Biol Chem
, vol.393
, pp. 1485-1512
-
-
Hill, B.G.1
Benavides, G.A.2
Lancaster Jr., J.R.3
Ballinger, S.4
Dell'Italia, L.5
Zhang, J.6
-
34
-
-
84155180848
-
P53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia
-
A. Hoshino, S. Matoba, E. Iwai-Kanai, H. Nakamura, M. Kimata, and M. Nakaoka et al. p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia J Mol Cell Cardiol 52 2012 175 184
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 175-184
-
-
Hoshino, A.1
Matoba, S.2
Iwai-Kanai, E.3
Nakamura, H.4
Kimata, M.5
Nakaoka, M.6
-
35
-
-
84882425828
-
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
-
A. Hoshino, Y. Mita, Y. Okawa, M. Ariyoshi, E. Iwai-Kanai, and T. Ueyama et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart Nat Commun 4 2013 2308
-
(2013)
Nat Commun
, vol.4
, pp. 2308
-
-
Hoshino, A.1
Mita, Y.2
Okawa, Y.3
Ariyoshi, M.4
Iwai-Kanai, E.5
Ueyama, T.6
-
36
-
-
79958172986
-
Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1
-
C. Huang, A.M. Andres, E.P. Ratliff, G. Hernandez, P. Lee, and R.A. Gottlieb Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1 PLoS ONE 6 2011 e20975
-
(2011)
PLoS ONE
, vol.6
, pp. 20975
-
-
Huang, C.1
Andres, A.M.2
Ratliff, E.P.3
Hernandez, G.4
Lee, P.5
Gottlieb, R.A.6
-
37
-
-
84867031150
-
Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
-
Y. Imaizumi, Y. Okada, W. Akamatsu, M. Koike, N. Kuzumaki, and H. Hayakawa et al. Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue Mol Brain 5 2012 35
-
(2012)
Mol Brain
, vol.5
, pp. 35
-
-
Imaizumi, Y.1
Okada, Y.2
Akamatsu, W.3
Koike, M.4
Kuzumaki, N.5
Hayakawa, H.6
-
38
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
I. Irrcher, H. Aleyasin, E.L. Seifert, S.J. Hewitt, S. Chhabra, and M. Phillips et al. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics Hum Mol Genet 19 2010 3734 3746
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
-
39
-
-
78649685455
-
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
-
S.M. Jin, M. Lazarou, C. Wang, L.A. Kane, D.P. Narendra, and R.J. Youle Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL J Cell Biol 191 2010 933 942
-
(2010)
J Cell Biol
, vol.191
, pp. 933-942
-
-
Jin, S.M.1
Lazarou, M.2
Wang, C.3
Kane, L.A.4
Narendra, D.P.5
Youle, R.J.6
-
40
-
-
84887486172
-
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
-
S.M. Jin, and R.J. Youle The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria Autophagy 9 2013 1750 1757
-
(2013)
Autophagy
, vol.9
, pp. 1750-1757
-
-
Jin, S.M.1
Youle, R.J.2
-
41
-
-
84868087279
-
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
-
A.P. Joselin, S.J. Hewitt, S.M. Callaghan, R.H. Kim, Y.H. Chung, and T.W. Mak et al. ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons Hum Mol Genet 21 2012 4888 4903
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4888-4903
-
-
Joselin, A.P.1
Hewitt, S.J.2
Callaghan, S.M.3
Kim, R.H.4
Chung, Y.H.5
Mak, T.W.6
-
42
-
-
84883487916
-
Casein kinase 2 is essential for mitophagy
-
T. Kanki, Y. Kurihara, X. Jin, T. Goda, Y. Ono, and M. Aihara et al. Casein kinase 2 is essential for mitophagy EMBO Rep 14 2013 788 794
-
(2013)
EMBO Rep
, vol.14
, pp. 788-794
-
-
Kanki, T.1
Kurihara, Y.2
Jin, X.3
Goda, T.4
Ono, Y.5
Aihara, M.6
-
43
-
-
67650264633
-
Atg32 is a mitochondrial protein that confers selectivity during mitophagy
-
T. Kanki, K. Wang, Y. Cao, M. Baba, and D.J. Klionsky Atg32 is a mitochondrial protein that confers selectivity during mitophagy Dev Cell 17 2009 98 109
-
(2009)
Dev Cell
, vol.17
, pp. 98-109
-
-
Kanki, T.1
Wang, K.2
Cao, Y.3
Baba, M.4
Klionsky, D.J.5
-
44
-
-
79251574964
-
Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation
-
I. Kim, and J.J. Lemasters Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation Am J Physiol Cell Physiol 300 2011 C308 C317
-
(2011)
Am J Physiol Cell Physiol
, vol.300
-
-
Kim, I.1
Lemasters, J.J.2
-
45
-
-
4644273585
-
Uth1p is involved in the autophagic degradation of mitochondria
-
DOI 10.1074/jbc.M406960200
-
I. Kissova, M. Deffieu, S. Manon, and N. Camougrand Uth1p is involved in the autophagic degradation of mitochondria J Biol Chem 279 2004 39068 39074 (Pubitemid 39296069)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.37
, pp. 39068-39074
-
-
Kissova, I.1
Deffieu, M.2
Manon, S.3
Camougrand, N.4
-
46
-
-
84872283780
-
Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction
-
D.A. Kubli, X. Zhang, Y. Lee, R.A. Hanna, M.N. Quinsay, and C.K. Nguyen et al. Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction J Biol Chem 288 2013 915 926
-
(2013)
J Biol Chem
, vol.288
, pp. 915-926
-
-
Kubli, D.A.1
Zhang, X.2
Lee, Y.3
Hanna, R.A.4
Quinsay, M.N.5
Nguyen, C.K.6
-
47
-
-
80053430056
-
GABARAPL1 (GEC1): Original or copycat?
-
J.N. Le Grand, F.Z. Chakrama, S. Seguin-Py, A. Fraichard, R. age-Mourroux, and M. Jouvenot et al. GABARAPL1 (GEC1): original or copycat? Autophagy 7 2011
-
(2011)
Autophagy
, vol.7
-
-
Le Grand, J.N.1
Chakrama, F.Z.2
Seguin-Py, S.3
Fraichard, A.4
Age-Mourroux, R.5
Jouvenot, M.6
-
48
-
-
84555195856
-
Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling
-
J. Lee, S. Giordano, and J. Zhang Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling Biochem J 441 2012 523 540
-
(2012)
Biochem J
, vol.441
, pp. 523-540
-
-
Lee, J.1
Giordano, S.2
Zhang, J.3
-
49
-
-
77952326081
-
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
-
J.Y. Lee, Y. Nagano, J.P. Taylor, K.L. Lim, and T.P. Yao Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy J Cell Biol 189 2010 671 679
-
(2010)
J Cell Biol
, vol.189
, pp. 671-679
-
-
Lee, J.Y.1
Nagano, Y.2
Taylor, J.P.3
Lim, K.L.4
Yao, T.P.5
-
50
-
-
84887464921
-
Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy
-
V. Lefebvre, Q. Du, S. Baird, A.C. Ng, M. Nascimento, and M. Campanella et al. Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy Autophagy 9 2013
-
(2013)
Autophagy
, vol.9
-
-
Lefebvre, V.1
Du, Q.2
Baird, S.3
Ng, A.C.4
Nascimento, M.5
Campanella, M.6
-
51
-
-
16844366524
-
Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging
-
J.J. Lemasters Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging Rejuvenation Res 8 2005 3 5
-
(2005)
Rejuvenation Res
, vol.8
, pp. 3-5
-
-
Lemasters, J.J.1
-
52
-
-
33846200292
-
Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer
-
DOI 10.1038/sj.onc.1209772, PII 1209772
-
A. Letessier, S. Garrido-Urbani, C. Ginestier, G. Fournier, B. Esterni, and F. Monville et al. Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer Oncogene 26 2007 298 307 (Pubitemid 46095741)
-
(2007)
Oncogene
, vol.26
, Issue.2
, pp. 298-307
-
-
Letessier, A.1
Garrido-Urbani, S.2
Ginestier, C.3
Fournier, G.4
Esterni, B.5
Monville, F.6
Adelaide, J.7
Geneix, J.8
Xerri, L.9
Dubreuil, P.10
Viens, P.11
Charafe-Jauffret, E.12
Jacquemier, J.13
Birnbaum, D.14
Lopez, M.15
Chaffanet, M.16
-
53
-
-
84896744676
-
Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria
-
K. Liu, Y. Shi, X.H. Guo, Y.B. Ouyang, S.S. Wang, and D.J. Liu et al. Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria Cell Death Dis 5 2014 e1078
-
(2014)
Cell Death Dis
, vol.5
, pp. 1078
-
-
Liu, K.1
Shi, Y.2
Guo, X.H.3
Ouyang, Y.B.4
Wang, S.S.5
Liu, D.J.6
-
54
-
-
84862789618
-
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
-
L. Liu, D. Feng, G. Chen, M. Chen, Q. Zheng, and P. Song et al. Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells Nat Cell Biol 14 2012 177 185
-
(2012)
Nat Cell Biol
, vol.14
, pp. 177-185
-
-
Liu, L.1
Feng, D.2
Chen, G.3
Chen, M.4
Zheng, Q.5
Song, P.6
-
56
-
-
84898864538
-
Recent advances in Parkinson's disease genetics
-
S. Lubbe, and H.R. Morris Recent advances in Parkinson's disease genetics J Neurol 261 2014 259 266
-
(2014)
J Neurol
, vol.261
, pp. 259-266
-
-
Lubbe, S.1
Morris, H.R.2
-
57
-
-
84880506979
-
The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy
-
K. Mao, K. Wang, X. Liu, and D.J. Klionsky The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy Dev Cell 26 2013 9 18
-
(2013)
Dev Cell
, vol.26
, pp. 9-18
-
-
Mao, K.1
Wang, K.2
Liu, X.3
Klionsky, D.J.4
-
58
-
-
79955701611
-
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
-
M.K. McCoy, and M.R. Cookson DJ-1 regulation of mitochondrial function and autophagy through oxidative stress Autophagy 7 2011
-
(2011)
Autophagy
, vol.7
-
-
McCoy, M.K.1
Cookson, M.R.2
-
59
-
-
84897863239
-
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
-
G.L. McLelland, V. Soubannier, C.X. Chen, H.M. McBride, and E.A. Fon Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control EMBO J 33 2014 282 295
-
(2014)
EMBO J
, vol.33
, pp. 282-295
-
-
McLelland, G.L.1
Soubannier, V.2
Chen, C.X.3
McBride, H.M.4
Fon, E.A.5
-
60
-
-
84877578621
-
Rheb regulates mitophagy induced by mitochondrial energetic status
-
S. Melser, E.H. Chatelain, J. Lavie, W. Mahfouf, C. Jose, and E. Obre et al. Rheb regulates mitophagy induced by mitochondrial energetic status Cell Metab 17 2013 719 730
-
(2013)
Cell Metab
, vol.17
, pp. 719-730
-
-
Melser, S.1
Chatelain, E.H.2
Lavie, J.3
Mahfouf, W.4
Jose, C.5
Obre, E.6
-
61
-
-
77952242572
-
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy
-
S. Michiorri, V. Gelmetti, E. Giarda, F. Lombardi, F. Romano, and R. Marongiu et al. The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy Cell Death Differ 17 2010 962 974
-
(2010)
Cell Death Differ
, vol.17
, pp. 962-974
-
-
Michiorri, S.1
Gelmetti, V.2
Giarda, E.3
Lombardi, F.4
Romano, F.5
Marongiu, R.6
-
62
-
-
84873197455
-
Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: Implications for mitochondrial therapeutics
-
T. Mitchell, B. Chacko, S.W. Ballinger, S.M. Bailey, J. Zhang, and V. Darley-Usmar Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics Biochem Soc Trans 41 2013 127 133
-
(2013)
Biochem Soc Trans
, vol.41
, pp. 127-133
-
-
Mitchell, T.1
Chacko, B.2
Ballinger, S.W.3
Bailey, S.M.4
Zhang, J.5
Darley-Usmar, V.6
-
63
-
-
84883792140
-
Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita+/Ins2-derived beta-cells
-
T. Mitchell, M.S. Johnson, X. Ouyang, B.K. Chacko, K. Mitra, and X. Lei et al. Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita+/Ins2-derived beta-cells Am J Physiol Endocrinol Metab 305 2013 E585 E599
-
(2013)
Am J Physiol Endocrinol Metab
, vol.305
-
-
Mitchell, T.1
Johnson, M.S.2
Ouyang, X.3
Chacko, B.K.4
Mitra, K.5
Lei, X.6
-
64
-
-
84884494185
-
SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria
-
H. Murata, M. Sakaguchi, K. Kataoka, and N.H. Huh SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria Mol Biol Cell 24 2013 2772 2784
-
(2013)
Mol Biol Cell
, vol.24
, pp. 2772-2784
-
-
Murata, H.1
Sakaguchi, M.2
Kataoka, K.3
Huh, N.H.4
-
65
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
M.P. Murphy How mitochondria produce reactive oxygen species Biochem J 417 2009 1 13
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
66
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
DOI 10.1038/nm1574, PII NM1574
-
A. Nakai, O. Yamaguchi, T. Takeda, Y. Higuchi, S. Hikoso, and M. Taniike et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress Nat Med 13 2007 619 624 (Pubitemid 46828485)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
Higuchi, Y.4
Hikoso, S.5
Taniike, M.6
Omiya, S.7
Mizote, I.8
Matsumura, Y.9
Asahi, M.10
Nishida, K.11
Hori, M.12
Mizushima, N.13
Otsu, K.14
-
67
-
-
78649300971
-
P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
-
D. Narendra, L.A. Kane, D.N. Hauser, I.M. Fearnley, and R.J. Youle p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both Autophagy 6 2010 1090 1106
-
(2010)
Autophagy
, vol.6
, pp. 1090-1106
-
-
Narendra, D.1
Kane, L.A.2
Hauser, D.N.3
Fearnley, I.M.4
Youle, R.J.5
-
68
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
D. Narendra, A. Tanaka, D.F. Suen, and R.J. Youle Parkin is recruited selectively to impaired mitochondria and promotes their autophagy J Cell Biol 183 2008 795 803
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
69
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
D.P. Narendra, S.M. Jin, A. Tanaka, D.F. Suen, C.A. Gautier, and J. Shen et al. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin PLoS Biol 8 2010 e1000298
-
(2010)
PLoS Biol
, vol.8
, pp. 1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
-
70
-
-
0037459081
-
Mitochondria: Releasing power for life and unleashing the machineries of death
-
DOI 10.1016/S0092-8674(03)00116-8
-
D.D. Newmeyer, and S. Ferguson-Miller Mitochondria: releasing power for life and unleashing the machineries of death Cell 112 2003 481 490 (Pubitemid 36263081)
-
(2003)
Cell
, vol.112
, Issue.4
, pp. 481-490
-
-
Newmeyer, D.D.1
Ferguson-Miller, S.2
-
71
-
-
84883763522
-
Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver
-
H.M. Ni, J.A. Williams, H. Jaeschke, and W.X. Ding Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver Redox Biol 1 2013 427 432
-
(2013)
Redox Biol
, vol.1
, pp. 427-432
-
-
Ni, H.M.1
Williams, J.A.2
Jaeschke, H.3
Ding, W.X.4
-
72
-
-
74049153002
-
Nix is a selective autophagy receptor for mitochondrial clearance
-
I. Novak, V. Kirkin, D.G. McEwan, J. Zhang, P. Wild, and A. Rozenknop et al. Nix is a selective autophagy receptor for mitochondrial clearance EMBO Rep 11 2010 45 51
-
(2010)
EMBO Rep
, vol.11
, pp. 45-51
-
-
Novak, I.1
Kirkin, V.2
McEwan, D.G.3
Zhang, J.4
Wild, P.5
Rozenknop, A.6
-
73
-
-
84860705893
-
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
-
T. Oka, S. Hikoso, O. Yamaguchi, M. Taneike, T. Takeda, and T. Tamai et al. Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure Nature 485 2012 251 255
-
(2012)
Nature
, vol.485
, pp. 251-255
-
-
Oka, T.1
Hikoso, S.2
Yamaguchi, O.3
Taneike, M.4
Takeda, T.5
Tamai, T.6
-
74
-
-
3442888541
-
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer
-
DOI 10.1158/0008-5472.CAN-04-0089
-
J. Okami, D.M. Simeone, and C.D. Logsdon Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer Cancer Res 64 2004 5338 5346 (Pubitemid 39006554)
-
(2004)
Cancer Research
, vol.64
, Issue.15
, pp. 5338-5346
-
-
Okami, J.1
Simeone, D.M.2
Logsdon, C.D.3
-
75
-
-
67650246357
-
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
-
K. Okamoto, N. Kondo-Okamoto, and Y. Ohsumi Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy Dev Cell 17 2009 87 97
-
(2009)
Dev Cell
, vol.17
, pp. 87-97
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
Ohsumi, Y.3
-
76
-
-
84868384387
-
Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase
-
K. Okatsu, S. Iemura, F. Koyano, E. Go, M. Kimura, and T. Natsume et al. Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase Biochem Biophys Res Commun 428 2012 197 202
-
(2012)
Biochem Biophys Res Commun
, vol.428
, pp. 197-202
-
-
Okatsu, K.1
Iemura, S.2
Koyano, F.3
Go, E.4
Kimura, M.5
Natsume, T.6
-
77
-
-
0037424239
-
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
-
DOI 10.1074/jbc.C200677200
-
A. Olichon, L. Baricault, N. Gas, E. Guillou, A. Valette, and P. Belenguer et al. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis J Biol Chem 278 2003 7743 7746 (Pubitemid 36800505)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.10
, pp. 7743-7746
-
-
Olichon, A.1
Baricault, L.2
Gas, N.3
Guillou, E.4
Valette, A.5
Belenguer, P.6
Lenaers, G.7
-
78
-
-
82555187810
-
Image-based genome-wide siRNA screen identifies selective autophagy factors
-
A. Orvedahl, R. Sumpter Jr., G. Xiao, A. Ng, Z. Zou, and Y. Tang et al. Image-based genome-wide siRNA screen identifies selective autophagy factors Nature 480 2011 113 117
-
(2011)
Nature
, vol.480
, pp. 113-117
-
-
Orvedahl, A.1
Sumpter Jr., R.2
Xiao, G.3
Ng, A.4
Zou, Z.5
Tang, Y.6
-
79
-
-
84887504016
-
Dynamin 1-like-dependent mitochondrial fission initiates overactive mitophagy in the hepatotoxicity of cadmium
-
H. Pi, S. Xu, L. Zhang, P. Guo, Y. Li, and J. Xie et al. Dynamin 1-like-dependent mitochondrial fission initiates overactive mitophagy in the hepatotoxicity of cadmium Autophagy 9 2013 1780 1800
-
(2013)
Autophagy
, vol.9
, pp. 1780-1800
-
-
Pi, H.1
Xu, S.2
Zhang, L.3
Guo, P.4
Li, Y.5
Xie, J.6
-
80
-
-
77955844260
-
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
-
A.C. Poole, R.E. Thomas, S. Yu, E.S. Vincow, and L. Pallanck The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway PLoS ONE 5 2010 e10054
-
(2010)
PLoS ONE
, vol.5
, pp. 10054
-
-
Poole, A.C.1
Thomas, R.E.2
Yu, S.3
Vincow, E.S.4
Pallanck, L.5
-
81
-
-
77956990244
-
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
-
G. Poulogiannis, R.E. McIntyre, M. Dimitriadi, J.R. Apps, C.H. Wilson, and K. Ichimura et al. PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice Proc Natl Acad Sci USA 107 2010 15145 15150
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15145-15150
-
-
Poulogiannis, G.1
McIntyre, R.E.2
Dimitriadi, M.3
Apps, J.R.4
Wilson, C.H.5
Ichimura, K.6
-
82
-
-
79952369437
-
Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts
-
A. Rakovic, A. Grunewald, J. Kottwitz, N. Bruggemann, P.P. Pramstaller, and K. Lohmann et al. Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts PLoS ONE 6 2011 e16746
-
(2011)
PLoS ONE
, vol.6
, pp. 16746
-
-
Rakovic, A.1
Grunewald, A.2
Kottwitz, J.3
Bruggemann, N.4
Pramstaller, P.P.5
Lohmann, K.6
-
83
-
-
77955029885
-
Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
-
A. Rakovic, A. Grunewald, P. Seibler, A. Ramirez, N. Kock, and S. Orolicki et al. Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients Hum Mol Genet 19 2010 3124 3137
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3124-3137
-
-
Rakovic, A.1
Grunewald, A.2
Seibler, P.3
Ramirez, A.4
Kock, N.5
Orolicki, S.6
-
84
-
-
84873843566
-
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
-
A. Rakovic, K. Shurkewitsch, P. Seibler, A. Grunewald, A. Zanon, and J. Hagenah et al. Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons J Biol Chem 288 2013 2223 2237
-
(2013)
J Biol Chem
, vol.288
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grunewald, A.4
Zanon, A.5
Hagenah, J.6
-
85
-
-
79959987510
-
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
-
A.S. Rambold, B. Kostelecky, N. Elia, and J. Lippincott-Schwartz Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation Proc Natl Acad Sci USA 108 2011 10190 10195
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 10190-10195
-
-
Rambold, A.S.1
Kostelecky, B.2
Elia, N.3
Lippincott-Schwartz, J.4
-
86
-
-
84860914473
-
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
-
J. Rehman, H.J. Zhang, P.T. Toth, Y. Zhang, G. Marsboom, and Z. Hong et al. Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer FASEB J 26 2012 2175 2186
-
(2012)
FASEB J
, vol.26
, pp. 2175-2186
-
-
Rehman, J.1
Zhang, H.J.2
Toth, P.T.3
Zhang, Y.4
Marsboom, G.5
Hong, Z.6
-
87
-
-
84874601438
-
Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment
-
A.F. Salem, M.S. Al-Zoubi, D. Whitaker-Menezes, U.E. Martinez-Outschoorn, R. Lamb, and J. Hulit et al. Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment Cell Cycle 12 2013 818 825
-
(2013)
Cell Cycle
, vol.12
, pp. 818-825
-
-
Salem, A.F.1
Al-Zoubi, M.S.2
Whitaker-Menezes, D.3
Martinez-Outschoorn, U.E.4
Lamb, R.5
Hulit, J.6
-
88
-
-
47049100413
-
Essential role for Nix in autophagic maturation of erythroid cells
-
DOI 10.1038/nature07006, PII NATURE07006
-
H. Sandoval, P. Thiagarajan, S.K. Dasgupta, A. Schumacher, J.T. Prchal, and M. Chen et al. Essential role for Nix in autophagic maturation of erythroid cells Nature 454 2008 232 235 (Pubitemid 351969889)
-
(2008)
Nature
, vol.454
, Issue.7201
, pp. 232-235
-
-
Sandoval, H.1
Thiagarajan, P.2
Dasgupta, S.K.3
Schumacher, A.4
Prchal, J.T.5
Chen, M.6
Wang, J.7
-
89
-
-
84876296881
-
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
-
S.A. Sarraf, M. Raman, V. Guarani-Pereira, M.E. Sowa, E.L. Huttlin, and S.P. Gygi et al. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization Nature 496 2013 372 376
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
Gygi, S.P.6
-
90
-
-
84891822234
-
Mutations in Fis1 disrupt orderly disposal of defective mitochondria
-
Q. Shen, K. Yamano, B.P. Head, S. Kawajiri, J.T. Cheung, and C. Wang et al. Mutations in Fis1 disrupt orderly disposal of defective mitochondria Mol Biol Cell 25 2014 145 159
-
(2014)
Mol Biol Cell
, vol.25
, pp. 145-159
-
-
Shen, Q.1
Yamano, K.2
Head, B.P.3
Kawajiri, S.4
Cheung, J.T.5
Wang, C.6
-
91
-
-
84875909195
-
Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation
-
X. Sun, M. Liu, J. Hao, D. Li, Y. Luo, and X. Wang et al. Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation Cell Cycle 12 2013 1133 1141
-
(2013)
Cell Cycle
, vol.12
, pp. 1133-1141
-
-
Sun, X.1
Liu, M.2
Hao, J.3
Li, D.4
Luo, Y.5
Wang, X.6
-
92
-
-
34247172582
-
Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival
-
DOI 10.1074/jbc.M605940200
-
R. Tal, G. Winter, N. Ecker, D.J. Klionsky, and H. Abeliovich Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival J Biol Chem 282 2007 5617 5624 (Pubitemid 47093789)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.8
, pp. 5617-5624
-
-
Tal, R.1
Winter, G.2
Ecker, N.3
Klionsky, D.J.4
Abeliovich, H.5
-
93
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
A. Tanaka, M.M. Cleland, S. Xu, D.P. Narendra, D.F. Suen, and M. Karbowski et al. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin J Cell Biol 191 2010 1367 1380
-
(2010)
J Cell Biol
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
-
94
-
-
79958050965
-
High-mobility group box 1 is essential for mitochondrial quality control
-
D. Tang, R. Kang, K.M. Livesey, G. Kroemer, T.R. Billiar, and H.B. Van et al. High-mobility group box 1 is essential for mitochondrial quality control Cell Metab 13 2011 701 711
-
(2011)
Cell Metab
, vol.13
, pp. 701-711
-
-
Tang, D.1
Kang, R.2
Livesey, K.M.3
Kroemer, G.4
Billiar, T.R.5
Van, H.B.6
-
95
-
-
79955557808
-
Rotenone, paraquat, and Parkinson's disease
-
C.M. Tanner, F. Kamel, G.W. Ross, J.A. Hoppin, S.M. Goldman, and M. Korell et al. Rotenone, paraquat, and Parkinson's disease Environ Health Perspect 119 2011 866 872
-
(2011)
Environ Health Perspect
, vol.119
, pp. 866-872
-
-
Tanner, C.M.1
Kamel, F.2
Ross, G.W.3
Hoppin, J.A.4
Goldman, S.M.5
Korell, M.6
-
96
-
-
84866641257
-
Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model
-
K.J. Thomas, and M.R. Jacobson Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model PLoS ONE 7 2012 e45319
-
(2012)
PLoS ONE
, vol.7
, pp. 45319
-
-
Thomas, K.J.1
Jacobson, M.R.2
-
97
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
-
K.J. Thomas, M.K. McCoy, J. Blackinton, A. Beilina, B.M. van der, and A. Sandebring et al. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy Hum Mol Genet 20 2011 40 50
-
(2011)
Hum Mol Genet
, vol.20
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
Beilina, A.4
Van Der, B.M.5
Sandebring, A.6
-
98
-
-
84881376726
-
Advances in the genetics of Parkinson disease
-
J. Trinh, and M. Farrer Advances in the genetics of Parkinson disease Nat Rev Neurol 9 2013 445 454
-
(2013)
Nat Rev Neurol
, vol.9
, pp. 445-454
-
-
Trinh, J.1
Farrer, M.2
-
99
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
DOI 10.1038/sj.emboj.7601963, PII 7601963
-
G. Twig, A. Elorza, A.J. Molina, H. Mohamed, J.D. Wikstrom, and G. Walzer et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy EMBO J 27 2008 433 446 (Pubitemid 351161653)
-
(2008)
EMBO Journal
, vol.27
, Issue.2
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.A.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
100
-
-
79954571354
-
The interplay between mitochondrial dynamics and mitophagy
-
G. Twig, and O.S. Shirihai The interplay between mitochondrial dynamics and mitophagy Antioxid Redox Signal 14 2011 1939 1951
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 1939-1951
-
-
Twig, G.1
Shirihai, O.S.2
-
101
-
-
79960407069
-
Parkin interacts with Ambra1 to induce mitophagy
-
H.C. Van, T. Cornelissen, H. Hofkens, W. Mandemakers, K. Gevaert, and S.B. De et al. Parkin interacts with Ambra1 to induce mitophagy J Neurosci 31 2011 10249 10261
-
(2011)
J Neurosci
, vol.31
, pp. 10249-10261
-
-
Van, H.C.1
Cornelissen, T.2
Hofkens, H.3
Mandemakers, W.4
Gevaert, K.5
De, S.B.6
-
102
-
-
79551603345
-
Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
-
L.V. Van, B. Arnold, S.J. Cassady, C.T. Chu, E.A. Burton, and S.B. Berman Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization Hum Mol Genet 20 2011 927 940
-
(2011)
Hum Mol Genet
, vol.20
, pp. 927-940
-
-
Van, L.V.1
Arnold, B.2
Cassady, S.J.3
Chu, C.T.4
Burton, E.A.5
Berman, S.B.6
-
103
-
-
73349125417
-
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies
-
S. Veeriah, B.S. Taylor, S. Meng, F. Fang, E. Yilmaz, and I. Vivanco et al. Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies Nat Genet 42 2010 77 82
-
(2010)
Nat Genet
, vol.42
, pp. 77-82
-
-
Veeriah, S.1
Taylor, B.S.2
Meng, S.3
Fang, F.4
Yilmaz, E.5
Vivanco, I.6
-
104
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
C. Vives-Bauza, C. Zhou, Y. Huang, M. Cui, R.L. de Vries, and J. Kim et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy Proc Natl Acad Sci USA 107 2010 378 383
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.5
Kim, J.6
-
105
-
-
84887472941
-
Proteolytic processing of Atg32 by the mitochondrial i-AAA protease Yme1 regulates mitophagy
-
K. Wang, M. Jin, X. Liu, and D.J. Klionsky Proteolytic processing of Atg32 by the mitochondrial i-AAA protease Yme1 regulates mitophagy Autophagy 9 2013
-
(2013)
Autophagy
, vol.9
-
-
Wang, K.1
Jin, M.2
Liu, X.3
Klionsky, D.J.4
-
106
-
-
84887597972
-
Restricted mitochondrial protein acetylation initiates mitochondrial autophagy
-
B.R. Webster, I. Scott, K. Han, J.H. Li, Z. Lu, and M.V. Stevens et al. Restricted mitochondrial protein acetylation initiates mitochondrial autophagy J Cell Sci 126 2013 4843 4849
-
(2013)
J Cell Sci
, vol.126
, pp. 4843-4849
-
-
Webster, B.R.1
Scott, I.2
Han, K.3
Li, J.H.4
Lu, Z.5
Stevens, M.V.6
-
107
-
-
84898652320
-
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
-
K. Yamano, A.I. Fogel, C. Wang, A.M. van der Bliek, and R.J. Youle Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy Elife 3 2014 e01612
-
(2014)
Elife
, vol.3
, pp. 01612
-
-
Yamano, K.1
Fogel, A.I.2
Wang, C.3
Van Der Bliek, A.M.4
Youle, R.J.5
-
108
-
-
79957472437
-
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
-
S.R. Yoshii, C. Kishi, N. Ishihara, and N. Mizushima Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane J Biol Chem 286 2011 19630 19640
-
(2011)
J Biol Chem
, vol.286
, pp. 19630-19640
-
-
Yoshii, S.R.1
Kishi, C.2
Ishihara, N.3
Mizushima, N.4
-
109
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
H. Zhang, M. Bosch-Marce, L.A. Shimoda, Y.S. Tan, J.H. Baek, and J.B. Wesley et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia J Biol Chem 283 2008 10892 10903
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
-
110
-
-
84879475204
-
Autophagy and mitophagy in cellular damage control
-
J. Zhang Autophagy and mitophagy in cellular damage control Redox Biol 1 2013 19 23
-
(2013)
Redox Biol
, vol.1
, pp. 19-23
-
-
Zhang, J.1
-
111
-
-
84885181954
-
Mitochondrial dynamics regulates migration and invasion of breast cancer cells
-
J. Zhao, J. Zhang, M. Yu, Y. Xie, Y. Huang, and D.W. Wolff et al. Mitochondrial dynamics regulates migration and invasion of breast cancer cells Oncogene 32 2013 4814 4824
-
(2013)
Oncogene
, vol.32
, pp. 4814-4824
-
-
Zhao, J.1
Zhang, J.2
Yu, M.3
Xie, Y.4
Huang, Y.5
Wolff, D.W.6
-
112
-
-
33847048316
-
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
-
DOI 10.2353/ajpath.2007.060524
-
J.H. Zhu, C. Horbinski, F. Guo, S. Watkins, Y. Uchiyama, and C.T. Chu Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death Am J Pathol 170 2007 75 86 (Pubitemid 47339191)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.1
, pp. 75-86
-
-
Zhu, J.-H.1
Horbinski, C.2
Guo, F.3
Watkins, S.4
Uchiyama, Y.5
Chu, C.T.6
-
113
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
E. Ziviani, R.N. Tao, and A.J. Whitworth Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin Proc Natl Acad Sci USA 107 2010 5018 5023
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
|