메뉴 건너뛰기




Volumn 1, Issue 4, 2012, Pages 192-198

Butyrate histone deacetylase inhibitors

Author keywords

Acylcarnitine; Butyrate; Butyrylcarnitine; Carnitine; Histone deacetylase

Indexed keywords

BUTYRIC ACID; HEMOGLOBIN F; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; PIVALOYLOXYMETHYL BUTYRATE; SHORT CHAIN FATTY ACID; TRIBUTYRIN; TRICHOSTATIN A; VORINOSTAT;

EID: 85043492396     PISSN: None     EISSN: 21647860     Source Type: Journal    
DOI: 10.1089/biores.2012.0223     Document Type: Article
Times cited : (138)

References (142)
  • 1
    • 0024996768 scopus 로고
    • Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
    • Yoshida M, Kijima M, Akita M, et al. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J Biol Chem. 1990;265:17174-17179.
    • (1990) J Biol Chem , vol.265 , pp. 17174-17179
    • Yoshida, M.1    Kijima, M.2    Akita, M.3
  • 2
    • 34548456881 scopus 로고    scopus 로고
    • Dietary histone deacetylase inhibitors: From cells to mice to man
    • Dashwood RH, Ho E. Dietary histone deacetylase inhibitors: From cells to mice to man. Semin Cancer Biol. 2007; 17:363-369.
    • (2007) Semin Cancer Biol , vol.17 , pp. 363-369
    • Dashwood, R.H.1    Ho, E.2
  • 3
    • 67349227787 scopus 로고    scopus 로고
    • Isoform-specific histone deacetylase inhibitors: The next step?
    • Balasubramanian S, Verner E, Buggy JJ. Isoform-specific histone deacetylase inhibitors: The next step? Cancer Lett. 2009;280:211-221.
    • (2009) Cancer Lett , vol.280 , pp. 211-221
    • Balasubramanian, S.1    Verner, E.2    Buggy, J.J.3
  • 4
    • 64249135764 scopus 로고    scopus 로고
    • Novel agents on the horizon for cancer therapy
    • Ma WW, Adjei AA. Novel agents on the horizon for cancer therapy. CA Cancer J Clin. 2009;59:111-137.
    • (2009) CA Cancer J Clin , vol.59 , pp. 111-137
    • Ma, W.W.1    Adjei, A.A.2
  • 5
    • 70349525349 scopus 로고    scopus 로고
    • Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors
    • Newkirk TL, Bowersab AA, Williams RM. Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors. Nat Prod Rep. 2009;26:1293-1320.
    • (2009) Nat Prod Rep , vol.26 , pp. 1293-1320
    • Newkirk, T.L.1    Bowersab, A.A.2    Williams, R.M.3
  • 6
    • 33947275876 scopus 로고    scopus 로고
    • A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies
    • Perrine SP, Hermine O, Small T, et al. A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies. Blood. 2007;109:2571-2578.
    • (2007) Blood , vol.109 , pp. 2571-2578
    • Perrine, S.P.1    Hermine, O.2    Small, T.3
  • 7
    • 71449109387 scopus 로고    scopus 로고
    • New patented histone deacetylase inhibitors
    • Wang H, Dymock BW. New patented histone deacetylase inhibitors. Expert Opin Ther Patents. 2009;19:1727-1757.
    • (2009) Expert Opin Ther Patents , vol.19 , pp. 1727-1757
    • Wang, H.1    Dymock, B.W.2
  • 8
    • 82955173014 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Emerging mechanisms of resistance
    • Robey RW, Chakraborty AR, Basseville A, et al. Histone deacetylase inhibitors: Emerging mechanisms of resistance. Mol Pharm. 2011;8:2021-2031.
    • (2011) Mol Pharm , vol.8 , pp. 2021-2031
    • Robey, R.W.1    Chakraborty, A.R.2    Basseville, A.3
  • 9
    • 67449145358 scopus 로고    scopus 로고
    • Rational combinations using HDAC inhibitors
    • Bots M, Johnstone RW. Rational combinations using HDAC inhibitors. Clin Cancer Res. 2009;15:3970-3977.
    • (2009) Clin Cancer Res , vol.15 , pp. 3970-3977
    • Bots, M.1    Johnstone, R.W.2
  • 10
    • 64049097640 scopus 로고    scopus 로고
    • The promises and pitfalls of epigenetic therapies in solid tumours
    • Graham JS, Kaye SB, Brown R. The promises and pitfalls of epigenetic therapies in solid tumours. Eur J Cancer. 2009; 45:1129-1136.
    • (2009) Eur J Cancer , vol.45 , pp. 1129-1136
    • Graham, J.S.1    Kaye, S.B.2    Brown, R.3
  • 11
    • 73949140461 scopus 로고    scopus 로고
    • Carboplatin and paclitaxel in combination with either vorinostat or placebo for first-line therapy of advanced non-small-cell lung cancer
    • Ramalingam SS, Maitland ML, Frankel P, et al. Carboplatin and paclitaxel in combination with either vorinostat or placebo for first-line therapy of advanced non-small-cell lung cancer. J Clin Oncol. 2010;28:56-62.
    • (2010) J Clin Oncol , vol.28 , pp. 56-62
    • Ramalingam, S.S.1    Maitland, M.L.2    Frankel, P.3
  • 12
    • 77649171884 scopus 로고    scopus 로고
    • Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
    • Tan J, Cang S, Ma Y, et al. Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents. J Hematol Oncol. 2010;3:5.
    • (2010) J Hematol Oncol , vol.3 , pp. 5
    • Tan, J.1    Cang, S.2    Ma, Y.3
  • 13
    • 70449345822 scopus 로고    scopus 로고
    • A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity
    • Griffith D, Morgan MP, Marmion CJ. A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity. Chem Commun. 2009;45:6735-6737.
    • (2009) Chem Commun , vol.45 , pp. 6735-6737
    • Griffith, D.1    Morgan, M.P.2    Marmion, C.J.3
  • 15
    • 74649085655 scopus 로고    scopus 로고
    • Novel therapeutic approaches to the treatment of metastatic breast cancer
    • Fernández Y, Cueva J, Palomo AG, et al. Novel therapeutic approaches to the treatment of metastatic breast cancer. Cancer Treat Rev. 2010;36:33-42.
    • (2010) Cancer Treat Rev , vol.36 , pp. 33-42
    • Fernández, Y.1    Cueva, J.2    Palomo, A.G.3
  • 16
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • Minucci S, Pelicci PG. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat Rev Cancer. 2006;6:38-51.
    • (2006) Nat Rev Cancer , vol.6 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 17
    • 70350524083 scopus 로고    scopus 로고
    • Resveratrol is not a direct activator of SIRT1 enzyme activity
    • Beher D, Wu J, Cumine S, et al. Resveratrol is not a direct activator of SIRT1 enzyme activity. Chem Biol Drug Des. 2009;74:619-624.
    • (2009) Chem Biol Drug Des , vol.74 , pp. 619-624
    • Beher, D.1    Wu, J.2    Cumine, S.3
  • 18
    • 70450231612 scopus 로고    scopus 로고
    • Energetics, epigenetics, mitochondrial genetics
    • Wallace DC, Fan W. Energetics, epigenetics, mitochondrial genetics. Mitochondrion. 2010;10:12-31.
    • (2010) Mitochondrion , vol.10 , pp. 12-31
    • Wallace, D.C.1    Fan, W.2
  • 19
    • 77953417440 scopus 로고    scopus 로고
    • Transcriptional regulation by class III histone deacetylases (sirtuins)
    • Dai Y, Faller DV. Transcriptional regulation by class III histone deacetylases (sirtuins). Transl Oncogenomics. 2008;3: 53-65.
    • (2008) Transl Oncogenomics , vol.3 , pp. 53-65
    • Dai, Y.1    Faller, D.V.2
  • 20
    • 53649086367 scopus 로고    scopus 로고
    • Mechanisms and molecular probes of sirtuins
    • Smith BC, Hallows WC, Denu JM. Mechanisms and molecular probes of sirtuins. Chem Biol. 2008;15:1002-1013.
    • (2008) Chem Biol , vol.15 , pp. 1002-1013
    • Smith, B.C.1    Hallows, W.C.2    Denu, J.M.3
  • 21
    • 55949129628 scopus 로고    scopus 로고
    • Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation
    • Bäckdahl L, Bushell A, Beck S. Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation. Int J Biochem Cell Biol. 2009;41:176-184.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 176-184
    • Bääckdahl, L.1    Bushell, A.2    Beck, S.3
  • 22
    • 67649379393 scopus 로고    scopus 로고
    • Histone acetyltransferase inhibitors and preclinical studies
    • Manzo F, Tambaro FP, Mai A, et al. Histone acetyltransferase inhibitors and preclinical studies. Expert Opin Ther Patents. 2009;19:761-774.
    • (2009) Expert Opin Ther Patents , vol.19 , pp. 761-774
    • Manzo, F.1    Tambaro, F.P.2    Mai, A.3
  • 23
    • 59849126153 scopus 로고    scopus 로고
    • Histone modifications dictate specific biological readouts
    • Munshi A, Shafi G, Aliya N, et al. Histone modifications dictate specific biological readouts. J Genet Genomics. 2009;36: 75-88.
    • (2009) J Genet Genomics , vol.36 , pp. 75-88
    • Munshi, A.1    Shafi, G.2    Aliya, N.3
  • 24
    • 67649619244 scopus 로고    scopus 로고
    • Putting the 'HAT' back on survival signalling: The promises and challenges of HDAC inhibition in the treatment of neurological conditions
    • Sleiman SF, Basso M, Mahishi L, et al. Putting the 'HAT' back on survival signalling: The promises and challenges of HDAC inhibition in the treatment of neurological conditions. Expert Opin Investig Drugs. 2009;18:573-584.
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 573-584
    • Sleiman, S.F.1    Basso, M.2    Mahishi, L.3
  • 25
    • 70350350917 scopus 로고    scopus 로고
    • Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells
    • Mellert HS, McMahon SB. Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells. Trends Biochem Sci. 2009;34:571-578.
    • (2009) Trends Biochem Sci , vol.34 , pp. 571-578
    • Mellert, H.S.1    McMahon, S.B.2
  • 26
    • 68949212379 scopus 로고    scopus 로고
    • Lysine acetylation targets protein complexes and co-regulates major cellular functions
    • Choudhary C, Kumar C, Gnad F, et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science. 2009;325:834-840.
    • (2009) Science , vol.325 , pp. 834-840
    • Choudhary, C.1    Kumar, C.2    Gnad, F.3
  • 27
  • 28
    • 77149179080 scopus 로고    scopus 로고
    • Rise of the rival
    • Norvell A, McMahon SB. Rise of the rival. Science. 2010; 327:964-968.
    • (2010) Science , vol.327 , pp. 964-968
    • Norvell, A.1    McMahon, S.B.2
  • 29
    • 77149148756 scopus 로고    scopus 로고
    • Regulation of cellular metabolism by protein lysine acetylation
    • Zhao S, Xu W, Jiang W, et al. Regulation of cellular metabolism by protein lysine acetylation. Science. 2010;327:1000-1004.
    • (2010) Science , vol.327 , pp. 1000-1004
    • Zhao, S.1    Xu, W.2    Jiang, W.3
  • 30
    • 0034654011 scopus 로고    scopus 로고
    • Acetylation: A regulatory modification to rival phosphorylation?
    • Kouzarides T. Acetylation: A regulatory modification to rival phosphorylation? EMBO J. 2000;19:1176-1179.
    • (2000) EMBO J , vol.19 , pp. 1176-1179
    • Kouzarides, T.1
  • 31
    • 34248640428 scopus 로고    scopus 로고
    • Lysine propionylation and butyrylation are novel post-translational modifications in histones
    • Chen Y, Sprung R, Tang Y, et al. Lysine propionylation and butyrylation are novel post-translational modifications in histones. Mol Cell Proteomics. 2007;6:812-819.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 812-819
    • Chen, Y.1    Sprung, R.2    Tang, Y.3
  • 32
    • 57049152851 scopus 로고    scopus 로고
    • Catalysis and substrate selection by histone/protein lysine acetyltransferases
    • Berndsen CE, Denu JM. Catalysis and substrate selection by histone/protein lysine acetyltransferases. Curr Opin Struct Biol. 2008;18:682-689.
    • (2008) Curr Opin Struct Biol , vol.18 , pp. 682-689
    • Berndsen, C.E.1    Denu, J.M.2
  • 33
    • 61849108746 scopus 로고    scopus 로고
    • Identificationandverification of lysine propionylation and butyrylation in yeast core histones using PTMap software
    • ZhangK, ChenY, ZhangZ, et al. Identificationandverification of lysine propionylation and butyrylation in yeast core histones using PTMap software. J Proteome Res. 2009;8:900-906.
    • (2009) J Proteome Res , vol.8 , pp. 900-906
    • Zhang, K.1    Chen, Y.2    Zhang, Z.3
  • 34
    • 70449534077 scopus 로고    scopus 로고
    • Synergistic interactions between histone deacetylase inhibitors and drugs of abuse
    • Adachi M, Monteggia LM. Synergistic interactions between histone deacetylase inhibitors and drugs of abuse. Nat Neuropsychopharmacol. 2009;34:2619-2620.
    • (2009) Nat Neuropsychopharmacol , vol.34 , pp. 2619-2620
    • Adachi, M.1    Monteggia, L.M.2
  • 35
    • 50949132079 scopus 로고    scopus 로고
    • Dietary manipulation of histone structure and function
    • Delage B, Dashwood RH. Dietary manipulation of histone structure and function. Annu Rev Nutr. 2008;28:347-366.
    • (2008) Annu Rev Nutr , vol.28 , pp. 347-366
    • Delage, B.1    Dashwood, R.H.2
  • 36
    • 53349103842 scopus 로고    scopus 로고
    • Diet and the epigenetic (re)programming of phenotypic differences in behavior
    • McGowan PO, Meaney MJ, Szyf M. Diet and the epigenetic (re)programming of phenotypic differences in behavior. Brain Res. 2008;1237:12-24.
    • (2008) Brain Res , vol.1237 , pp. 12-24
    • McGowan, P.O.1    Meaney, M.J.2    Szyf, M.3
  • 37
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl BD, Allis D. The language of covalent histone modifications. Nature. 2000;403:41-45.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, D.2
  • 38
    • 77954067539 scopus 로고    scopus 로고
    • Histone code-breakers: The technologies of an epigenetic enigma
    • Perkel JM. Histone code-breakers: The technologies of an epigenetic enigma. Biotechniques. 2010;48:185-191.
    • (2010) Biotechniques , vol.48 , pp. 185-191
    • Perkel, J.M.1
  • 39
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer, Past, present and future
    • Yoo CB, Jones PA. Epigenetic therapy of cancer: Past, present and future. Nat Rev Drug Discov. 2006;5:37-50.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 40
    • 73349092441 scopus 로고    scopus 로고
    • Histones: Annotating chromatin
    • Campos EI, Reinberg D. Histones: Annotating chromatin. Annu Rev Genet. 2009;43:559-599.
    • (2009) Annu Rev Genet , vol.43 , pp. 559-599
    • Campos, E.I.1    Reinberg, D.2
  • 41
    • 74049144159 scopus 로고    scopus 로고
    • Primer: Induced pluripotency
    • de Souza M. Primer: Induced pluripotency. Nat Methods. 2010;7:20-21.
    • (2010) Nat Methods , vol.7 , pp. 20-21
    • de Souza, M.1
  • 42
    • 76149134398 scopus 로고    scopus 로고
    • IPSCs: One cell to rule them all?
    • Eisenstein M. IPSCs: One cell to rule them all? Nat Methods. 2010;7:81-85.
    • (2010) Nat Methods , vol.7 , pp. 81-85
    • Eisenstein, M.1
  • 43
    • 71449125977 scopus 로고    scopus 로고
    • Forcing cells to change lineages
    • Graf T, Enver T. Forcing cells to change lineages. Nature. 2009;462:587-504.
    • (2009) Nature , vol.462 , pp. 587-504
    • Graf, T.1    Enver, T.2
  • 46
    • 35848945959 scopus 로고    scopus 로고
    • Design, synthesis, structure-selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors
    • Itoh Y, Suzuki T, Kouketsu A, et al. Design, synthesis, structure-selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem. 2007;50:5425-5438.
    • (2007) J Med Chem , vol.50 , pp. 5425-5438
    • Itoh, Y.1    Suzuki, T.2    Kouketsu, A.3
  • 47
    • 34548494128 scopus 로고    scopus 로고
    • 2-Aroylindoles and 2-aroylbenzofurans with N-hydroxyacrylamide substructures as a novel series of rationally designed histone deacetylase inhibitors
    • Mahboobi S, Sellmer A, Höcher H, et al. 2-Aroylindoles and 2-aroylbenzofurans with N-hydroxyacrylamide substructures as a novel series of rationally designed histone deacetylase inhibitors. J Med Chem. 2007;50:4405-4418.
    • (2007) J Med Chem , vol.50 , pp. 4405-4418
    • Mahboobi, S.1    Sellmer, A.2    Höcher, H.3
  • 48
    • 38749136234 scopus 로고    scopus 로고
    • Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1 2)
    • Methot JL, Chakravarty PK, Chenard M, et al. Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2). Bioorg Med Chem Lett. 2008;18:973-978.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 973-978
    • Methot, J.L.1    Chakravarty, P.K.2    Chenard, M.3
  • 49
    • 66749129628 scopus 로고    scopus 로고
    • Discovery of a potent class I selective ketone histone deacetylase inhibitor with antitumor activity in vivo and optimized pharmacokinetic properties
    • Kinzel O, Llauger-Bufi L, Pescatore G, et al. Discovery of a potent class I selective ketone histone deacetylase inhibitor with antitumor activity in vivo and optimized pharmacokinetic properties. J Med Chem. 2009;52:3453-3456.
    • (2009) J Med Chem , vol.52 , pp. 3453-3456
    • Kinzel, O.1    Llauger-Bufi, L.2    Pescatore, G.3
  • 50
    • 77955480670 scopus 로고    scopus 로고
    • Strategies in developing promising histone deacetylase inhibitors
    • Zhang L, Fang H, Xu W. Strategies in developing promising histone deacetylase inhibitors. Med Res Rev. 2010;30:585-602.
    • (2010) Med Res Rev , vol.30 , pp. 585-602
    • Zhang, L.1    Fang, H.2    Xu, W.3
  • 51
    • 84055190790 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: History and new QSAR perspectives
    • Pontiki E, Hadjipavlou-Litina D. Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: History and new QSAR perspectives. Med Res Rev. 2012;32:1-165.
    • (2012) Med Res Rev , vol.32 , pp. 1-165
    • Pontiki, E.1    Hadjipavlou-Litina, D.2
  • 52
    • 51449109026 scopus 로고    scopus 로고
    • The use of lamb rennet paste in traditional sheep milk cheese production
    • Addis M, Piredda G, Pirisi A. The use of lamb rennet paste in traditional sheep milk cheese production. Small Ruminant Res. 2008;79:2-10.
    • (2008) Small Ruminant Res , vol.79 , pp. 2-10
    • Addis, M.1    Piredda, G.2    Pirisi, A.3
  • 53
    • 65249168646 scopus 로고    scopus 로고
    • Probiotic in lamb rennet paste enhances rennet lipolytic activity, and conjugated linoleic acid and linoleic acid content in pecorino cheese
    • Santillo A, Albenzio M, Quinto M, et al. Probiotic in lamb rennet paste enhances rennet lipolytic activity, and conjugated linoleic acid and linoleic acid content in pecorino cheese. J Dairy Sci. 2009;92:1330-1337.
    • (2009) J Dairy Sci , vol.92 , pp. 1330-1337
    • Santillo, A.1    Albenzio, M.2    Quinto, M.3
  • 54
    • 4444247315 scopus 로고    scopus 로고
    • Cellular and physiological effects of short-chain fatty acids
    • Miller SJ. Cellular and physiological effects of short-chain fatty acids. Mini Rev Med Chem. 2004;4:839-845.
    • (2004) Mini Rev Med Chem , vol.4 , pp. 839-845
    • Miller, S.J.1
  • 55
    • 48649087037 scopus 로고    scopus 로고
    • Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon
    • Waldecker M, Kautenburger T, Daumann H, et al. Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. J Nutr Biochem. 2008;19:587-593.
    • (2008) J Nutr Biochem , vol.19 , pp. 587-593
    • Waldecker, M.1    Kautenburger, T.2    Daumann, H.3
  • 56
    • 68749119436 scopus 로고    scopus 로고
    • Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fiber
    • Scharlau D, Borowicki A, Habermann N, et al. Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fiber. Mutat Res. 2009;682:39-53.
    • (2009) Mutat Res , vol.682 , pp. 39-53
    • Scharlau, D.1    Borowicki, A.2    Habermann, N.3
  • 57
    • 78649877232 scopus 로고    scopus 로고
    • Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells
    • Serpa J, Caiado F, Carvalho T, et al. Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells. J Biol Chem. 2010;285:39211-39223.
    • (2010) J Biol Chem , vol.285 , pp. 39211-39223
    • Serpa, J.1    Caiado, F.2    Carvalho, T.3
  • 58
    • 79956362344 scopus 로고    scopus 로고
    • Metabolism as a key to histone deacetylase inhibition
    • Rajendran P, Williams DE, Ho E, et al. Metabolism as a key to histone deacetylase inhibition. Crit Rev Biochem Mol. 2011;46:181-199.
    • (2011) Crit Rev Biochem Mol , vol.46 , pp. 181-199
    • Rajendran, P.1    Williams, D.E.2    Ho, E.3
  • 59
    • 0035888083 scopus 로고    scopus 로고
    • Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecological cancer cells
    • Terao Y, Nishida J-I, Horiuchi S, et al. Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecological cancer cells. Int J Cancer. 2001;94:257-267.
    • (2001) Int J Cancer , vol.94 , pp. 257-267
    • Terao, Y.1    Nishida, J.-I.2    Horiuchi, S.3
  • 60
    • 79952384705 scopus 로고    scopus 로고
    • Cancer epigenetics reaches mainstream oncology
    • Rodríguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat Med. 2011;17:330-339.
    • (2011) Nat Med , vol.17 , pp. 330-339
    • Rodríguez-Paredes, M.1    Esteller, M.2
  • 61
    • 58149145317 scopus 로고    scopus 로고
    • Butyrate metabolism in human colon carcinoma cells: Implications concerning its growth-inhibitory effect
    • Andriamihaja M, Chaumontet C, Tome D, et al. Butyrate metabolism in human colon carcinoma cells: Implications concerning its growth-inhibitory effect. J Cell Physiol. 2009;218:58-65.
    • (2009) J Cell Physiol , vol.218 , pp. 58-65
    • Andriamihaja, M.1    Chaumontet, C.2    Tome, D.3
  • 62
    • 77952306758 scopus 로고    scopus 로고
    • Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells
    • Zhang Y, Zhou L, Bao YL, et al. Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells. Chem-Biol Interact. 2010; 185:174-181.
    • (2010) Chem-Biol Interact , vol.185 , pp. 174-181
    • Zhang, Y.1    Zhou, L.2    Bao, Y.L.3
  • 63
    • 80054084433 scopus 로고    scopus 로고
    • Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies
    • Crea F, Nobili S, Paolicchi E, et al. Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies. Drug Resist Updates. 2011;14:280-296.
    • (2011) Drug Resist Updates , vol.14 , pp. 280-296
    • Crea, F.1    Nobili, S.2    Paolicchi, E.3
  • 64
    • 84858281362 scopus 로고    scopus 로고
    • Effect of butyrate on aromatase cytochrome P450 levels in HT29, DLD-1 and LoVo colon cancer cells
    • Raw1uszko AA, S1awek S, Gollogly A, et al. Effect of butyrate on aromatase cytochrome P450 levels in HT29, DLD-1 and LoVo colon cancer cells. Biomed Pharmacother. 2012; 66:77-82.
    • (2012) Biomed Pharmacother , vol.66 , pp. 77-82
    • Raw1uszko, A.A.1    S1awek, S.2    Gollogly, A.3
  • 65
    • 84855178148 scopus 로고    scopus 로고
    • Histone deacetylase inhibition as an anticancer telomerase-targeting strategy
    • Rahman R, Grundy R. Histone deacetylase inhibition as an anticancer telomerase-targeting strategy. Int J Cancer. 2011; 129:2765-2774.
    • (2011) Int J Cancer , vol.129 , pp. 2765-2774
    • Rahman, R.1    Grundy, R.2
  • 66
    • 77955501968 scopus 로고    scopus 로고
    • Butyrate promotes induced pluripotent stem cell generation
    • Liang G, Taranova O, Xia K, et al. Butyrate promotes induced pluripotent stem cell generation. J Biol Chem. 2010; 285:25516-25521.
    • (2010) J Biol Chem , vol.285 , pp. 25516-25521
    • Liang, G.1    Taranova, O.2    Xia, K.3
  • 67
    • 77950965653 scopus 로고    scopus 로고
    • Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes
    • Mali P, Chou B-K, Yen J, et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells. 2010;28:713-720.
    • (2010) Stem Cells , vol.28 , pp. 713-720
    • Mali, P.1    Chou, B.-K.2    Yen, J.3
  • 68
    • 74949106388 scopus 로고    scopus 로고
    • Differentiation of mouse embryonic stem cells into hepatocytes induced by a combination of cytokines and sodium butyrate
    • Zhou M, Li P, Tan L, et al. Differentiation of mouse embryonic stem cells into hepatocytes induced by a combination of cytokines and sodium butyrate. J Cell Biochem. 2010; 109:606-614.
    • (2010) J Cell Biochem , vol.109 , pp. 606-614
    • Zhou, M.1    Li, P.2    Tan, L.3
  • 69
    • 78650680751 scopus 로고    scopus 로고
    • Chemical control of stem cell fate and developmental potential
    • Lyssiotis CA, Lairson LL, Boitano AE, et al. Chemical control of stem cell fate and developmental potential. Angew Chem Int Ed. 2011;50:200-242.
    • (2011) Angew Chem Int Ed , vol.50 , pp. 200-242
    • Lyssiotis, C.A.1    Lairson, L.L.2    Boitano, A.E.3
  • 70
    • 84855867526 scopus 로고    scopus 로고
    • Epigenetic regulation of self-renewal and fate determination in neural stem cells
    • Ariff IM, Mitra A, Anirban Basu A. Epigenetic regulation of self-renewal and fate determination in neural stem cells. J Neurosci Res. 2012;90:529-539.
    • (2012) J Neurosci Res , vol.90 , pp. 529-539
    • Ariff, I.M.1    Mitra, A.2    Anirban Basu, A.3
  • 71
    • 84855398949 scopus 로고    scopus 로고
    • Concise review, Human cell engineering: Cellular reprogramming and genome editing
    • Mali P, Cheng L. Concise review: Human cell engineering: Cellular reprogramming and genome editing. Stem Cells. 2012;30:75-81.
    • (2012) Stem Cells , vol.30 , pp. 75-81
    • Mali, P.1    Cheng, L.2
  • 72
    • 70349931949 scopus 로고    scopus 로고
    • In vitro studies on the inhibition of colon cancer by butyrate and carnitine
    • Roy M-J, Dionne S, Marx G, et al. In vitro studies on the inhibition of colon cancer by butyrate and carnitine. Nutrition. 2009;25:1193-1201.
    • (2009) Nutrition , vol.25 , pp. 1193-1201
    • Roy, M.-J.1    Dionne, S.2    Marx, G.3
  • 73
    • 79953309326 scopus 로고    scopus 로고
    • Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex
    • Blouin J-M, Penot G, Collinet M, et al. Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex. Int J Cancer. 2011;128: 2591-2601.
    • (2011) Int J Cancer , vol.128 , pp. 2591-2601
    • Blouin, J.-M.1    Penot, G.2    Collinet, M.3
  • 74
    • 84860229552 scopus 로고    scopus 로고
    • The epigenetic effects of butyrate: Potential therapeutic implications for clinical practice
    • Canani RB, Di Costanzo M, Leone L. The epigenetic effects of butyrate: Potential therapeutic implications for clinical practice. Clin Epigenetics. 2012;4:4.
    • (2012) Clin Epigenetics , vol.4 , pp. 4
    • Canani, R.B.1    Di Costanzo, M.2    Leone, L.3
  • 75
    • 65549123471 scopus 로고    scopus 로고
    • HDAC2 negatively regulates memory formation and synaptic plasticity
    • Guan J-S, Haggarty SJ, Giacometti E, et al. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature. 2009, 459:55-60.
    • (2009) Nature , vol.459 , pp. 55-60
    • Guan, J.-S.1    Haggarty, S.J.2    Giacometti, E.3
  • 76
    • 67651146826 scopus 로고    scopus 로고
    • The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain
    • Kim HJ, Leeds P, Chuang D-M. The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain. J Neurochem. 2009;110:1226-1240.
    • (2009) J Neurochem , vol.110 , pp. 1226-1240
    • Kim, H.J.1    Leeds, P.2    Chuang, D.-M.3
  • 77
    • 78649636357 scopus 로고    scopus 로고
    • Epigenetic therapies for non-oncology indications
    • Best JD, Carey N. Epigenetic therapies for non-oncology indications. Drug Discov Today. 2010;15:1008-1014.
    • (2010) Drug Discov Today , vol.15 , pp. 1008-1014
    • Best, J.D.1    Carey, N.2
  • 78
    • 79952003783 scopus 로고    scopus 로고
    • Histone deacetylases in skeletal development and bone mass maintenance
    • McGee-Lawrence ME, Westendorf JJ. Histone deacetylases in skeletal development and bone mass maintenance. Gene. 2011;474:1-11.
    • (2011) Gene , vol.474 , pp. 1-11
    • McGee-Lawrence, M.E.1    Westendorf, J.J.2
  • 79
    • 33845518649 scopus 로고    scopus 로고
    • Targeting glycosylation pathways and the cell cycle: Sugardependent activity of butyrate-carbohydrate cancer prodrugs
    • Sampathkumar S-G, Jones MB, Meledeo MA, et al. Targeting glycosylation pathways and the cell cycle: Sugardependent activity of butyrate-carbohydrate cancer prodrugs. Chem Biol. 2006;13:1265-1275.
    • (2006) Chem Biol , vol.13 , pp. 1265-1275
    • Sampathkumar, S.-G.1    Jones, M.B.2    Meledeo, M.A.3
  • 80
    • 39749091215 scopus 로고    scopus 로고
    • Molecular basis of sodium butyrate-dependent proapoptotic activity in cancer cells
    • Pajak B, Orzechowski A, Gajkowska B. Molecular basis of sodium butyrate-dependent proapoptotic activity in cancer cells. Adv Med Sci. 2007;52:83-88.
    • (2007) Adv Med Sci , vol.52 , pp. 83-88
    • Pajak, B.1    Orzechowski, A.2    Gajkowska, B.3
  • 81
    • 70350461683 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells
    • Lee S, Park J-R, Seo M-S, et al. Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells. Cell Prolif. 2009;42:711-722.
    • (2009) Cell Prolif , vol.42 , pp. 711-722
    • Lee, S.1    Park, J.-R.2    Seo, M.-S.3
  • 82
    • 67649238355 scopus 로고    scopus 로고
    • Butyrate improves insulin sensitivity and increases energy expenditure in mice
    • Gao Z, Yin J, Zhang J, et al. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes. 2009;58:1509-1517.
    • (2009) Diabetes , vol.58 , pp. 1509-1517
    • Gao, Z.1    Yin, J.2    Zhang, J.3
  • 83
    • 0037114756 scopus 로고    scopus 로고
    • Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo
    • Pace BS, White GL, Dover GJ, et al. Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo. Blood. 2002;100:4640-4648.
    • (2002) Blood , vol.100 , pp. 4640-4648
    • Pace, B.S.1    White, G.L.2    Dover, G.J.3
  • 84
    • 33344459039 scopus 로고    scopus 로고
    • Fetal globin induction-can it cure b thalassemia?
    • Perrine SP. Fetal globin induction-can it cure b thalassemia? Hematology. 2005;1:38-44.
    • (2005) Hematology , vol.1 , pp. 38-44
    • Perrine, S.P.1
  • 85
    • 65349157826 scopus 로고    scopus 로고
    • Erythroid Kruppel-like factor (EKLF) is recruited to the c-globin gene promoter as a co-activator and is required for c-globin gene induction by short-chain fatty acid derivatives
    • Perrine SP, Mankidy R, Boosalis MS, et al. Erythroid Kruppel-like factor (EKLF) is recruited to the c-globin gene promoter as a co-activator and is required for c-globin gene induction by short-chain fatty acid derivatives. Eur J Haematol. 2009;82:466-476.
    • (2009) Eur J Haematol , vol.82 , pp. 466-476
    • Perrine, S.P.1    Mankidy, R.2    Boosalis, M.S.3
  • 86
    • 79955932718 scopus 로고    scopus 로고
    • Potential beneficial effects of butyrate in intestinal and extraintestinal diseases
    • Canani RB, Di Costanzo M, Leone L, et al. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol. 2011;17:1519-1528.
    • (2011) World J Gastroenterol , vol.17 , pp. 1519-1528
    • Canani, R.B.1    Di Costanzo, M.2    Leone, L.3
  • 87
    • 82355175410 scopus 로고    scopus 로고
    • Histone deacetylases and mood disorders: Epigenetic programming in gene-environment interactions
    • Machado-Vieira R, Ibrahim L, Zarate, Jr., CA. Histone deacetylases and mood disorders: Epigenetic programming in gene-environment interactions. CNS Neurosci Ther. 2011;17:699-704.
    • (2011) CNS Neurosci Ther , vol.17 , pp. 699-704
    • Machado-Vieira, R.1    Ibrahim, L.2    Zarate Jr., C.A.3
  • 88
    • 84862938325 scopus 로고    scopus 로고
    • Butyrate activates the cAMPprotein kinase A cAMP response element-binding protein signaling pathway in Caco-2 cells
    • Wang A, Si H, Liu D, et al. Butyrate activates the cAMPprotein kinase A cAMP response element-binding protein signaling pathway in Caco-2 cells. J Nutr. 2012;142:1-6.
    • (2012) J Nutr , vol.142 , pp. 1-6
    • Wang, A.1    Si, H.2    Liu, D.3
  • 89
    • 0037369256 scopus 로고    scopus 로고
    • Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin
    • Witt O, Mönkemeyer S, Rönndahl G, et al. Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. Blood. 2003;101:2001-2007.
    • (2003) Blood , vol.101 , pp. 2001-2007
    • Witt, O.1    Mönkemeyer, S.2    Rönndahl, G.3
  • 90
    • 30344476415 scopus 로고    scopus 로고
    • Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas
    • Entin-Meer M, Rephaeli A, Yang X, et al. Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas. Mol Cancer Ther. 2005;4:1952-1961.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1952-1961
    • Entin-Meer, M.1    Rephaeli, A.2    Yang, X.3
  • 91
    • 33745183358 scopus 로고    scopus 로고
    • Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models
    • Bohacek R, Boosalis MS, McMartin C, et al. Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models. Chem Biol Drug Des. 2006;67:318-328.
    • (2006) Chem Biol Drug Des , vol.67 , pp. 318-328
    • Bohacek, R.1    Boosalis, M.S.2    McMartin, C.3
  • 92
    • 34248644319 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors-turning epigenic mechanisms of gene regulation into tools of therapeutic intervention in malignant and other diseases
    • Riester D, Hildmann C, Schwienhorst A. Histone deacetylase inhibitors-turning epigenic mechanisms of gene regulation into tools of therapeutic intervention in malignant and other diseases. Appl Microbiol Biotechnol. 2007;75: 499-514.
    • (2007) Appl Microbiol Biotechnol , vol.75 , pp. 499-514
    • Riester, D.1    Hildmann, C.2    Schwienhorst, A.3
  • 93
    • 38649087344 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid 2,2-dimethylbutyrate (NSC 741804), in rat plasma
    • Parise RA, Beumera JH, Kangani CO, et al. Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma. J Chromatogr B. 2008;862:168-174.
    • (2008) J Chromatogr B , vol.862 , pp. 168-174
    • Parise, R.A.1    Beumera, J.H.2    Kangani, C.O.3
  • 94
    • 64249133886 scopus 로고    scopus 로고
    • Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors, Efficacy of tributyrin, a butyric acid prodrug
    • Kuroiwa-Trzmielina J, de Conti A, Scolastici C, et al. Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: Efficacy of tributyrin, a butyric acid prodrug. Int J Cancer. 2009;124:2520-2527.
    • (2009) Int J Cancer , vol.124 , pp. 2520-2527
    • Kuroiwa-Trzmielina, J.1    de Conti, A.2    Scolastici, C.3
  • 95
    • 84863039812 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents
    • Ghosh SK, Perrine SP, Williams RM, et al. Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents. Blood. 2012;119:1008-1017.
    • (2012) Blood , vol.119 , pp. 1008-1017
    • Ghosh, S.K.1    Perrine, S.P.2    Williams, R.M.3
  • 96
    • 0035111343 scopus 로고    scopus 로고
    • Prodrugs of butyric acid. Novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases
    • Nudelman A, Gnizi E, Katz Y, et al. Prodrugs of butyric acid. Novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases. Eur J Med. 2001;36:63-74.
    • (2001) Eur J Med , vol.36 , pp. 63-74
    • Nudelman, A.1    Gnizi, E.2    Katz, Y.3
  • 97
    • 84857916369 scopus 로고    scopus 로고
    • A histone deacetylase inhibitory prodrug-butyroyloxymethyl diethyl phosphate-protects the heart and cardiomyocytes against ischemia injury
    • Kessler-Icekson G, Hochhauser E, Sinai T, et al. A histone deacetylase inhibitory prodrug-butyroyloxymethyl diethyl phosphate-protects the heart and cardiomyocytes against ischemia injury. Eur J Pharm Sci. 2012;45:592-599.
    • (2012) Eur J Pharm Sci , vol.45 , pp. 592-599
    • Kessler-Icekson, G.1    Hochhauser, E.2    Sinai, T.3
  • 98
    • 33745021853 scopus 로고    scopus 로고
    • The selectivity and anti-metastatic activity of oral bioavailable butyric acid prodrugs
    • Rephaeli A, Entin-Meer M, Angel D, et al. The selectivity and anti-metastatic activity of oral bioavailable butyric acid prodrugs. Invest New Drugs. 2006;24:383-392.
    • (2006) Invest New Drugs , vol.24 , pp. 383-392
    • Rephaeli, A.1    Entin-Meer, M.2    Angel, D.3
  • 99
    • 41649109389 scopus 로고    scopus 로고
    • Prodrugs for the treatment of neglected diseases
    • Chung MC, Ferreira EI, Santos JL, et al. Prodrugs for the treatment of neglected diseases. Molecules. 2008;13:616-677.
    • (2008) Molecules , vol.13 , pp. 616-677
    • Chung, M.C.1    Ferreira, E.I.2    Santos, J.L.3
  • 100
    • 53949087611 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors, The anticancer, antimetastatic and antiangiogenic activities of AN-7 are superior to those of the clinically tested AN-9 (Pivanex)
    • Tarasenko N, Nudelman A, Tarasenko I, et al. Histone deacetylase inhibitors: The anticancer, antimetastatic and antiangiogenic activities of AN-7 are superior to those of the clinically tested AN-9 (Pivanex). Clin Exp Metastasis. 2008;25:703-716.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 703-716
    • Tarasenko, N.1    Nudelman, A.2    Tarasenko, I.3
  • 101
    • 56149090684 scopus 로고    scopus 로고
    • Epi-drugs to fight cancer, From chemistry to cancer treatment, the road ahead
    • Mai A, Altucci L. Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead. Int J Biochem Cell Biol. 2009;41:199-213.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 199-213
    • Mai, A.1    Altucci, L.2
  • 102
    • 0027078611 scopus 로고
    • A short-term trial of butyrate to stimulate fetal globin gene expression in the b globin gene disorders
    • Perrine SP, Ginder G, Faller DV, et al. A short-term trial of butyrate to stimulate fetal globin gene expression in the b globin gene disorders. N Engl J Med. 1993;328:81-86.
    • (1993) N Engl J Med , vol.328 , pp. 81-86
    • Perrine, S.P.1    Ginder, G.2    Faller, D.V.3
  • 103
    • 0033559320 scopus 로고    scopus 로고
    • Hematologic responses to pulse butyrate therapy in the beta-hemoglobinopathies
    • Atweh GF, Dover GJ, Ikuta T, et al. Hematologic responses to pulse butyrate therapy in the beta-hemoglobinopathies. Blood. 1999;93:1790-1797.
    • (1999) Blood , vol.93 , pp. 1790-1797
    • Atweh, G.F.1    Dover, G.J.2    Ikuta, T.3
  • 104
    • 77955906235 scopus 로고    scopus 로고
    • Fetal globin gene inducersd: Novel agents and new potential
    • Perrine SP, Castaneda SA, Chui DH, et al. Fetal globin gene inducers: Novel agents and new potential. Ann NY Acad Sci. 2010;1202:158-164.
    • (2010) Ann NY Acad Sci , vol.1202 , pp. 158-164
    • Perrine, S.P.1    Castaneda, S.A.2    Chui, D.H.3
  • 105
    • 78349240687 scopus 로고    scopus 로고
    • A randomized phase II trial of arginine butyrate with standard local therapy in refractory sickle cell leg ulcers
    • McMahon L, Tamary H, Askin M, et al. A randomized phase II trial of arginine butyrate with standard local therapy in refractory sickle cell leg ulcers. Br J Haematol. 2010;151:516-524.
    • (2010) Br J Haematol , vol.151 , pp. 516-524
    • McMahon, L.1    Tamary, H.2    Askin, M.3
  • 106
    • 67650078931 scopus 로고    scopus 로고
    • Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies
    • Bora-Tatar G, Dayangaç-Erden D, Demir AS, et al. Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies. Bioorg Med Chem. 2009;17:5219-5228.
    • (2009) Bioorg Med Chem , vol.17 , pp. 5219-5228
    • Bora-Tatar, G.1    Dayangaç-Erden, D.2    Demir, A.S.3
  • 107
    • 84862596071 scopus 로고    scopus 로고
    • Sodium valproate inhibits MDA-MB-231 breast cancer cell migration by upregulating NM23H1 expression
    • Li G-F, Qian T-L, Li G-S, et al. Sodium valproate inhibits MDA-MB-231 breast cancer cell migration by upregulating NM23H1 expression. Genet Mol Res. 2012;11:77-86.
    • (2012) Genet Mol Res , vol.11 , pp. 77-86
    • Li, G.-F.1    Qian, T.-L.2    Li, G.-S.3
  • 108
    • 33645233142 scopus 로고    scopus 로고
    • Structure- activity relationship between carboxylic acids and T cell cycle blockade
    • Gilbert KM, DeLoose A, Valentine JL, et al. Structure- activity relationship between carboxylic acids and T cell cycle blockade. Life Sci. 2006;78:2159-2165.
    • (2006) Life Sci , vol.78 , pp. 2159-2165
    • Gilbert, K.M.1    DeLoose, A.2    Valentine, J.L.3
  • 109
    • 0035874544 scopus 로고    scopus 로고
    • Shortchain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation
    • Boosalis MS, Bandyopadhyay R, Bresnick EH, et al. Shortchain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation. Blood. 2001;97:3259-3267.
    • (2001) Blood , vol.97 , pp. 3259-3267
    • Boosalis, M.S.1    Bandyopadhyay, R.2    Bresnick, E.H.3
  • 110
    • 24644449060 scopus 로고    scopus 로고
    • Enhancement of growth and survival and alterations in Bcl-family proteins in β-thalassemic erythroid progenitors by novel shortchain fatty acid derivatives
    • Castaneda S, Boosalis MS, Emery D, et al. Enhancement of growth and survival and alterations in Bcl-family proteins in β-thalassemic erythroid progenitors by novel shortchain fatty acid derivatives. Blood Cells Mol Dis. 2005;35: 217-226.
    • (2005) Blood Cells Mol Dis , vol.35 , pp. 217-226
    • Castaneda, S.1    Boosalis, M.S.2    Emery, D.3
  • 111
    • 0348223762 scopus 로고    scopus 로고
    • 2+ -chelating motiftethered short-chain fatty acids as a novel class of histone deacetylase inhibitors
    • 2+ -chelating motiftethered short-chain fatty acids as a novel class of histone deacetylase inhibitors. J Med Chem. 2004;47:467-474.
    • (2004) J Med Chem , vol.47 , pp. 467-474
    • Lu, Q.1    Yang, Y.-T.2    Chen, C.-S.3
  • 112
    • 23944487678 scopus 로고    scopus 로고
    • Structure-based optimization of phenylbutyrate-derived histone deacetylase inhibitors
    • Lu Q, Wang D-S, Chen C-S, et al. Structure-based optimization of phenylbutyrate-derived histone deacetylase inhibitors. J Med Chem. 2005;48:5530-5535.
    • (2005) J Med Chem , vol.48 , pp. 5530-5535
    • Lu, Q.1    Wang, D.-S.2    Chen, C.-S.3
  • 113
    • 33947594149 scopus 로고    scopus 로고
    • Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid
    • Bieliauskas AV, Weerasinghe SVW, Pflum MKH. Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid. Bioorg Med Chem Lett. 2007;17:2216-2219.
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 2216-2219
    • Bieliauskas, A.V.1    Weerasinghe, S.V.W.2    Pflum, M.K.H.3
  • 114
    • 38149079799 scopus 로고    scopus 로고
    • Optimization of biaryl selective HDAC1&2 inhibitors (SHI-1 2)
    • Witter DJ, Harrington P, Wilson KJ, et al. Optimization of biaryl selective HDAC1&2 inhibitors (SHI-1:2). Bioorg Med Chem Lett. 2008;18:726-731.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 726-731
    • Witter, D.J.1    Harrington, P.2    Wilson, K.J.3
  • 115
    • 60549095162 scopus 로고    scopus 로고
    • Novel amide derivatives as inhibitors of histone deacetylase, Design, synthesis and SAR
    • Andrianov V, Gailite V, Lola D, et al. Novel amide derivatives as inhibitors of histone deacetylase: Design, synthesis and SAR. Eur J Med Chem. 2009;44:1067-1085.
    • (2009) Eur J Med Chem , vol.44 , pp. 1067-1085
    • Andrianov, V.1    Gailite, V.2    Lola, D.3
  • 116
    • 79957839068 scopus 로고    scopus 로고
    • Interpreting clinical assays for histone deacetylase inhibitors
    • Martinet N, Bertrand P. Interpreting clinical assays for histone deacetylase inhibitors. Cancer Manage Res. 2011;3: 117-141.
    • (2011) Cancer Manage Res , vol.3 , pp. 117-141
    • Martinet, N.1    Bertrand, P.2
  • 117
    • 58249089741 scopus 로고    scopus 로고
    • Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3
    • Thangaraju M, Carswell KN, Prasad PD, et al. Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. Biochem J. 2009; 417:379-389.
    • (2009) Biochem J , vol.417 , pp. 379-389
    • Thangaraju, M.1    Carswell, K.N.2    Prasad, P.D.3
  • 118
    • 70649112278 scopus 로고    scopus 로고
    • Lactic acid in cancer and mitochondrial disease
    • Steliou K, Perrine SP, Faller DV. Lactic acid in cancer and mitochondrial disease. Drug Dev Res. 2009;70:499-511.
    • (2009) Drug Dev Res , vol.70 , pp. 499-511
    • Steliou, K.1    Perrine, S.P.2    Faller, D.V.3
  • 119
    • 33645969256 scopus 로고    scopus 로고
    • SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter
    • Gupta N, Martin PM, Prasad PD, et al. SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter. Life Sci. 2006; 78:2419-2425.
    • (2006) Life Sci , vol.78 , pp. 2419-2425
    • Gupta, N.1    Martin, P.M.2    Prasad, P.D.3
  • 120
    • 57749111596 scopus 로고    scopus 로고
    • Nutrient transporters in cancerp: Relevance to Warburg hypothesis and beyond
    • Ganapathy V, Thangaraju M, Prasad PD. Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond. Pharmacol Therapeut. 2009;121:29-40.
    • (2009) Pharmacol Therapeut , vol.121 , pp. 29-40
    • Ganapathy, V.1    Thangaraju, M.2    Prasad, P.D.3
  • 121
    • 11844275233 scopus 로고    scopus 로고
    • A family of fatty acid binding receptors
    • Brown AJ, Jupe S, Briscoe CP. A family of fatty acid binding receptors. DNA Cell Biol. 2005;24:54-61.
    • (2005) DNA Cell Biol , vol.24 , pp. 54-61
    • Brown, A.J.1    Jupe, S.2    Briscoe, C.P.3
  • 122
    • 80855160956 scopus 로고    scopus 로고
    • Non-natural sugar analogues, Chemical probes for metabolic oligosaccharide engineering
    • Fraser-Reid B, Tatsuta K, Thiem J. (eds.) Springer-Verlag, Berlin, Germany
    • Aich U, Yarema KJ. Non-natural sugar analogues: Chemical probes for metabolic oligosaccharide engineering. In: Glycoscience. Fraser-Reid B, Tatsuta K, Thiem J. (eds.) Springer-Verlag: Berlin, Germany; pp. 2133-2190; 2008.
    • (2008) Glycoscience , pp. 2133-2190
    • Aich, U.1    Yarema, K.J.2
  • 123
    • 77249174795 scopus 로고    scopus 로고
    • Recent developments in carbohydrate-decorated targeted drug/gene delivery
    • Zhang H, Ma Y, Sun X-L. Recent developments in carbohydrate-decorated targeted drug/gene delivery. Med Res Rev. 2010;30:270-289.
    • (2010) Med Res Rev , vol.30 , pp. 270-289
    • Zhang, H.1    Ma, Y.2    Sun, X.-L.3
  • 124
    • 84859573465 scopus 로고    scopus 로고
    • In vitro 2-deoxy-2-[18F]fluoro-D-glucose uptake: Practical considerations
    • Mertens K, Mees G, Lambert B, et al. In vitro 2-deoxy-2-[18F]fluoro-D-glucose uptake: Practical considerations. Cancer Biother Radiopharm. 2012;27:183-188.
    • (2012) Cancer Biother Radiopharm , vol.27 , pp. 183-188
    • Mertens, K.1    Mees, G.2    Lambert, B.3
  • 125
    • 65249090141 scopus 로고    scopus 로고
    • Hexosamine template: A platform for modulating gene expression and for sugar-based drug discovery
    • Elmouelhi N, Aich U, Paruchuri VDP, et al. Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. J Med Chem. 2009;52: 2515-2530.
    • (2009) J Med Chem , vol.52 , pp. 2515-2530
    • Elmouelhi, N.1    Aich, U.2    Paruchuri, V.D.P.3
  • 126
    • 70349208720 scopus 로고    scopus 로고
    • Carbohydrates: A frontier in medicinal chemistry
    • Stallforth P, Lepenies B, Adibekian A, et al. Carbohydrates: A frontier in medicinal chemistry. J Med Chem. 2009;52: 5561-5577.
    • (2009) J Med Chem , vol.52 , pp. 5561-5577
    • Stallforth, P.1    Lepenies, B.2    Adibekian, A.3
  • 127
    • 70549098258 scopus 로고    scopus 로고
    • Hexosamine analogs: From metabolic glycoengineering to drug discovery
    • Wang Z, Du J, Che P-L, et al. Hexosamine analogs: From metabolic glycoengineering to drug discovery. Curr Opin Chem Biol. 2009;13:565-572.
    • (2009) Curr Opin Chem Biol , vol.13 , pp. 565-572
    • Wang, Z.1    Du, J.2    Che, P.-L.3
  • 128
    • 10044232836 scopus 로고    scopus 로고
    • Establishment of N-acetylmannosamine (ManNAc) analogue-resistant cell lines as improved hosts for sialic acid engineering applications
    • Kim EJ, Jones MB, Rhee JK, et al. Establishment of N-acetylmannosamine (ManNAc) analogue-resistant cell lines as improved hosts for sialic acid engineering applications. Biotechnol Prog. 2004;20:1674-1682.
    • (2004) Biotechnol Prog , vol.20 , pp. 1674-1682
    • Kim, E.J.1    Jones, M.B.2    Rhee, J.K.3
  • 129
    • 33847131811 scopus 로고    scopus 로고
    • Metabolic oligosaccharide engineering, Perspectives, applications, and future directions
    • Campbell CT, Sampathkumar S-G, Yarema KJ. Metabolic oligosaccharide engineering: Perspectives, applications, and future directions. Mol Biosyst. 2007;3:187-194.
    • (2007) Mol Biosyst , vol.3 , pp. 187-194
    • Campbell, C.T.1    Sampathkumar, S.-G.2    Yarema, K.J.3
  • 130
    • 58149097138 scopus 로고    scopus 로고
    • Targeting proinvasive oncogenes with short chain fatty acid-hexosamine analogues inhibits the mobility of metastatic MDA-MB-231 breast cancer cells
    • Campbell CT, Aich U, Weier CA, et al. Targeting proinvasive oncogenes with short chain fatty acid-hexosamine analogues inhibits the mobility of metastatic MDA-MB-231 breast cancer cells. J Med Chem. 2008;51:8135-8147.
    • (2008) J Med Chem , vol.51 , pp. 8135-8147
    • Campbell, C.T.1    Aich, U.2    Weier, C.A.3
  • 131
    • 84857440170 scopus 로고    scopus 로고
    • Metabolic oligosaccharide engineering with N-acyl functionalized ManNAc analogs, Cytotoxicity, metabolic flux, and glycan-display considerations
    • Almaraz RT, Aich U, Khanna HS, et al. Metabolic oligosaccharide engineering with N-acyl functionalized ManNAc analogs: Cytotoxicity, metabolic flux, and glycan-display considerations. Biotechnol Bioeng. 2012;109:992-1006.
    • (2012) Biotechnol Bioeng , vol.109 , pp. 992-1006
    • Almaraz, R.T.1    Aich, U.2    Khanna, H.S.3
  • 132
    • 78651284859 scopus 로고    scopus 로고
    • D-Galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice
    • Parameshwaran K, Irwin MH, Steliou K, et al. D-Galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice. Rejuv Res. 2010;13:729-735.
    • (2010) Rejuv Res , vol.13 , pp. 729-735
    • Parameshwaran, K.1    Irwin, M.H.2    Steliou, K.3
  • 133
    • 84857699370 scopus 로고    scopus 로고
    • Antioxidant protection of rotenone-induced neuromotor decline, ROS generation and cellular stress in mouse brain
    • Parameshwaran K, Irwin MH, Steliou K, et al. Antioxidant protection of rotenone-induced neuromotor decline, ROS generation and cellular stress in mouse brain. Pharmacol Biochem Behav. 2012;101:487-492.
    • (2012) Pharmacol Biochem Behav , vol.101 , pp. 487-492
    • Parameshwaran, K.1    Irwin, M.H.2    Steliou, K.3
  • 134
    • 4444372351 scopus 로고    scopus 로고
    • Carnitine: Transport and physiological functions in the brain
    • Na1ezcz KA, Miecz D, Berezowski V, et al. Carnitine: Transport and physiological functions in the brain. Mol Aspects Med. 2004;25:551-567.
    • (2004) Mol Aspects Med , vol.25 , pp. 551-567
    • Na1ezcz, K.A.1    Miecz, D.2    Berezowski, V.3
  • 136
    • 58149381840 scopus 로고    scopus 로고
    • Synthesis of carnitine benzyl esters as prodrugs
    • Gong X-w, Li J-p, Wu J-f, et al. Synthesis of carnitine benzyl esters as prodrugs. J Chem Res. 2008;2008:327-330.
    • (2008) J Chem Res , vol.2008 , pp. 327-330
    • Gong, X.-W.1    Li, J.-P.2    Wu, J.-F.3
  • 137
    • 38849090084 scopus 로고    scopus 로고
    • Synthesis and characterization of carnitine nitro-derivatives
    • Piermatti O, Fringuelli F, Pochini L, et al. Synthesis and characterization of carnitine nitro-derivatives. Bioorg Med Chem. 2008;16:1444-1451.
    • (2008) Bioorg Med Chem , vol.16 , pp. 1444-1451
    • Piermatti, O.1    Fringuelli, F.2    Pochini, L.3
  • 138
    • 71549116704 scopus 로고    scopus 로고
    • Mitochondria in the elderly: Is acetylcarnitine a rejuvenator?
    • Rosca MG, Lemieux H, Hoppel CL. Mitochondria in the elderly: Is acetylcarnitine a rejuvenator? Adv Drug Deliver Rev. 2009;61:1332-1342.
    • (2009) Adv Drug Deliver Rev , vol.61 , pp. 1332-1342
    • Rosca, M.G.1    Lemieux, H.2    Hoppel, C.L.3
  • 139
    • 0345687134 scopus 로고
    • Der abbau aromatischer fettsäuren im tierkörper (The degradation of aromatic fatty acids in the animal body)
    • Knoop F. Der abbau aromatischer fettsäuren im tierkörper (The degradation of aromatic fatty acids in the animal body). Beitr Chem Physiol Pathol. 1904;6:150-162.
    • (1904) Beitr Chem Physiol Pathol , vol.6 , pp. 150-162
    • Knoop, F.1
  • 140
    • 77957608608 scopus 로고    scopus 로고
    • A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation
    • Houten SM, Wanders RJA. A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation. J Inherit Metab Dis. 2010;33:469-477.
    • (2010) J Inherit Metab Dis , vol.33 , pp. 469-477
    • Houten, S.M.1    Wanders, R.J.A.2
  • 142
    • 0020371958 scopus 로고
    • Possible functions of short-chain and medium-chain carnitine acyltransferases
    • Bieber LL, Emaus R, Valkner K, et al. Possible functions of short-chain and medium-chain carnitine acyltransferases. Fed Proc. 1982;41:2858-2862.
    • (1982) Fed Proc , vol.41 , pp. 2858-2862
    • Bieber, L.L.1    Emaus, R.2    Valkner, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.