-
2
-
-
0021008492
-
Carnitine
-
Borum P.R. Carnitine. Annu Rev Nutr 3 (1983) 233-259
-
(1983)
Annu Rev Nutr
, vol.3
, pp. 233-259
-
-
Borum, P.R.1
-
3
-
-
4444311812
-
Carnitine acyltransferases and their influence on CoA pools in health and disease
-
Ramsay R.R., and Zammit V.A. Carnitine acyltransferases and their influence on CoA pools in health and disease. Mol Aspects Med 25 (2004) 475-493
-
(2004)
Mol Aspects Med
, vol.25
, pp. 475-493
-
-
Ramsay, R.R.1
Zammit, V.A.2
-
4
-
-
10644253401
-
The role of the carnitine system in human metabolism
-
Foster D.W. The role of the carnitine system in human metabolism. Ann NY Acad Sci 1033 (2004) 1-16
-
(2004)
Ann NY Acad Sci
, vol.1033
, pp. 1-16
-
-
Foster, D.W.1
-
5
-
-
0038128249
-
Structure of human carnitine acetyltransferase - molecular basis for fatty acyl transfer
-
Wu D.H., Govindasamy L., Lian W., et al. Structure of human carnitine acetyltransferase - molecular basis for fatty acyl transfer. J Biol Chem 278 (2003) 13159-13165
-
(2003)
J Biol Chem
, vol.278
, pp. 13159-13165
-
-
Wu, D.H.1
Govindasamy, L.2
Lian, W.3
-
6
-
-
3843062433
-
Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase
-
Hsiao Y.S., Jogl G., and Tong L. Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase. J Biol Chem 279 (2004) 31584-31589
-
(2004)
J Biol Chem
, vol.279
, pp. 31584-31589
-
-
Hsiao, Y.S.1
Jogl, G.2
Tong, L.3
-
7
-
-
1642483426
-
Changes in blood carnitine and acylcarnitine profiles of very long-chain acyl-CoA dehydrogenase-deficient mice subjected to stress
-
Spiekerkoetter U., Tokunaga C., Wendel U., et al. Changes in blood carnitine and acylcarnitine profiles of very long-chain acyl-CoA dehydrogenase-deficient mice subjected to stress. Eur J Clin Invest 34 (2004) 191-196
-
(2004)
Eur J Clin Invest
, vol.34
, pp. 191-196
-
-
Spiekerkoetter, U.1
Tokunaga, C.2
Wendel, U.3
-
8
-
-
0036840197
-
Acylcarnitine profiles of preterm infants over the first four weeks of life
-
Meyburg J., Schulze A., Kohlmueller D., et al. Acylcarnitine profiles of preterm infants over the first four weeks of life. Pediatr Res 52 (2002) 720-723
-
(2002)
Pediatr Res
, vol.52
, pp. 720-723
-
-
Meyburg, J.1
Schulze, A.2
Kohlmueller, D.3
-
9
-
-
17744413018
-
Diagnosis of very long chain acyl-dehydrogenase deficiency from an infant's newborn screening card
-
Wood J.C., Magera M.J., Rinaldo P., Seashore M.R., Strauss A.W., and Friedman A. Diagnosis of very long chain acyl-dehydrogenase deficiency from an infant's newborn screening card. Pediatrics 108 (2001) E19
-
(2001)
Pediatrics
, vol.108
-
-
Wood, J.C.1
Magera, M.J.2
Rinaldo, P.3
Seashore, M.R.4
Strauss, A.W.5
Friedman, A.6
-
10
-
-
36649020263
-
Metabolomics identifies perturbations in human disorders of propionate metabolism
-
Wikoff W.R., Gangoiti J.A., Barshop B.A., and Siuzdak G. Metabolomics identifies perturbations in human disorders of propionate metabolism. Clin Chem 53 (2007) 2169-2176
-
(2007)
Clin Chem
, vol.53
, pp. 2169-2176
-
-
Wikoff, W.R.1
Gangoiti, J.A.2
Barshop, B.A.3
Siuzdak, G.4
-
11
-
-
0036133045
-
Neonatal biochemical screening for disease
-
Clague A., and Thomas A. Neonatal biochemical screening for disease. Clin Chim Acta 315 (2002) 99-110
-
(2002)
Clin Chim Acta
, vol.315
, pp. 99-110
-
-
Clague, A.1
Thomas, A.2
-
12
-
-
0035197204
-
Postnatal changes in neonatal acylcarnitine profile
-
Meyburg J., Schulze A., Kohlmueller D., Linderkamp O., and Mayatepek E. Postnatal changes in neonatal acylcarnitine profile. Pediatr Res 49 (2001) 125-129
-
(2001)
Pediatr Res
, vol.49
, pp. 125-129
-
-
Meyburg, J.1
Schulze, A.2
Kohlmueller, D.3
Linderkamp, O.4
Mayatepek, E.5
-
13
-
-
0036405455
-
The application of tandem mass spectrometry to neonatal screening for inherited disorders of intermediary metabolism
-
Chace D.H., Kalas T.A., and Naylor E.W. The application of tandem mass spectrometry to neonatal screening for inherited disorders of intermediary metabolism. Annu Rev Genom Hum Genet 3 (2002) 17-45
-
(2002)
Annu Rev Genom Hum Genet
, vol.3
, pp. 17-45
-
-
Chace, D.H.1
Kalas, T.A.2
Naylor, E.W.3
-
14
-
-
10744220582
-
Rare disorders of metabolism with elevated butyryl- and isobutyryl-carnitine detected by tandem mass spectrometry newborn screening
-
Koeberl D.D., Young S.P., Gregersen N., et al. Rare disorders of metabolism with elevated butyryl- and isobutyryl-carnitine detected by tandem mass spectrometry newborn screening. Pediatr Res 54 (2003) 219-223
-
(2003)
Pediatr Res
, vol.54
, pp. 219-223
-
-
Koeberl, D.D.1
Young, S.P.2
Gregersen, N.3
-
15
-
-
16244409538
-
Age-related variations in acylcarnitine and free carnitine concentrations measured by tandem mass spectrometry
-
Cavedon C.T., Bourdoux P., Mertens K., et al. Age-related variations in acylcarnitine and free carnitine concentrations measured by tandem mass spectrometry. Clin Chem 51 (2005) 745-752
-
(2005)
Clin Chem
, vol.51
, pp. 745-752
-
-
Cavedon, C.T.1
Bourdoux, P.2
Mertens, K.3
-
17
-
-
0020035186
-
Luminal ions and short chain fatty acids as markers of functional activity of the mucosa in ulcerative colitis
-
Roediger W.E., Heyworth M., Willoughby P., Piris J., Moore A., and Truelove S.C. Luminal ions and short chain fatty acids as markers of functional activity of the mucosa in ulcerative colitis. J Clin Pathol 35 (1982) 323-326
-
(1982)
J Clin Pathol
, vol.35
, pp. 323-326
-
-
Roediger, W.E.1
Heyworth, M.2
Willoughby, P.3
Piris, J.4
Moore, A.5
Truelove, S.C.6
-
18
-
-
30444447247
-
Plasma carnitine ester profile in adult celiac disease patients maintained on long-term gluten free diet
-
Bene J., Komlosi K., Gasztonyi B., Juhasz M., Tulassay Z., and Melegh B. Plasma carnitine ester profile in adult celiac disease patients maintained on long-term gluten free diet. World J Gastroenterol 11 (2005)
-
(2005)
World J Gastroenterol
, vol.11
-
-
Bene, J.1
Komlosi, K.2
Gasztonyi, B.3
Juhasz, M.4
Tulassay, Z.5
Melegh, B.6
-
19
-
-
31144471584
-
Changes of plasma fasting carnitine ester profile in patients with ulcerative colitis
-
Bene J., Komlosi K., Havasi V., et al. Changes of plasma fasting carnitine ester profile in patients with ulcerative colitis. World J Gastroenterol 12 (2006) 110-113
-
(2006)
World J Gastroenterol
, vol.12
, pp. 110-113
-
-
Bene, J.1
Komlosi, K.2
Havasi, V.3
-
20
-
-
66749094133
-
Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women
-
Adams S.H., Hoppel C.L., Lok K.H., et al. Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women. J Nutr 139 (2009) 1073-1081
-
(2009)
J Nutr
, vol.139
, pp. 1073-1081
-
-
Adams, S.H.1
Hoppel, C.L.2
Lok, K.H.3
-
21
-
-
33646521552
-
Biochemical findings in common inborn errors of metabolism
-
Pasquali M., Monsen G., Richardson L., Alston M., and Longo N. Biochemical findings in common inborn errors of metabolism. Am J Med Genet C Semin Med Genet 142C (2006) 64-76
-
(2006)
Am J Med Genet C Semin Med Genet
, vol.142 C
, pp. 64-76
-
-
Pasquali, M.1
Monsen, G.2
Richardson, L.3
Alston, M.4
Longo, N.5
-
22
-
-
34547955729
-
Propionyl-l-carnitine prevents age-related myocardial remodeling in the rabbit
-
Orlandi A., Francesconi A., Ferlosio A., et al. Propionyl-l-carnitine prevents age-related myocardial remodeling in the rabbit. J Cardiovasc Pharmacol 50 (2007) 168-175
-
(2007)
J Cardiovasc Pharmacol
, vol.50
, pp. 168-175
-
-
Orlandi, A.1
Francesconi, A.2
Ferlosio, A.3
-
23
-
-
34547653749
-
Palmitoylcarnitine regulates estrification of lipids and promotes palmitoylation of GAP-43
-
Nalecz K.A., Szczepankowska D., Czeredys M., Kulikova N., and Grzeskiewicz S. Palmitoylcarnitine regulates estrification of lipids and promotes palmitoylation of GAP-43. FEBS Lett 581 (2007) 3950-3954
-
(2007)
FEBS Lett
, vol.581
, pp. 3950-3954
-
-
Nalecz, K.A.1
Szczepankowska, D.2
Czeredys, M.3
Kulikova, N.4
Grzeskiewicz, S.5
-
24
-
-
0000646490
-
Carnitine and derivatives in rat tissues
-
Pearson D.J., and Tubbs P.K. Carnitine and derivatives in rat tissues. Biochem J 105 (1967) 953-963
-
(1967)
Biochem J
, vol.105
, pp. 953-963
-
-
Pearson, D.J.1
Tubbs, P.K.2
-
25
-
-
0018150670
-
Effect of fasting on free and esterified carnitine levels in human serum and urine: correlation with serum levels of free fatty acids and B-hydroxybutyrate
-
Frohlich J., Seccombe D.W., Hahn P., Dodek P., and Hynie I. Effect of fasting on free and esterified carnitine levels in human serum and urine: correlation with serum levels of free fatty acids and B-hydroxybutyrate. Metabolism 27 (1978) 555-561
-
(1978)
Metabolism
, vol.27
, pp. 555-561
-
-
Frohlich, J.1
Seccombe, D.W.2
Hahn, P.3
Dodek, P.4
Hynie, I.5
-
26
-
-
0018694393
-
Plasma and urine carnitine in diabetic ketosis
-
Genuth S.M., and Hoppel C.L. Plasma and urine carnitine in diabetic ketosis. Diabetes 28 (1979) 1083-1087
-
(1979)
Diabetes
, vol.28
, pp. 1083-1087
-
-
Genuth, S.M.1
Hoppel, C.L.2
-
27
-
-
0019015876
-
Carnitine metabolism in normal-weight and obese human subjects during fasting
-
Hoppel C.L., and Genuth S.M. Carnitine metabolism in normal-weight and obese human subjects during fasting. Am J Physiol 238 (1980) E409-E415
-
(1980)
Am J Physiol
, vol.238
-
-
Hoppel, C.L.1
Genuth, S.M.2
-
28
-
-
0030983840
-
The effect of starvation on brain carnitine concentration in neonatal rats
-
Murakami R., Tanaka A., and Nakamura H. The effect of starvation on brain carnitine concentration in neonatal rats. J Pediatr Gastroenterol Nutr 25 (1997) 385-387
-
(1997)
J Pediatr Gastroenterol Nutr
, vol.25
, pp. 385-387
-
-
Murakami, R.1
Tanaka, A.2
Nakamura, H.3
-
29
-
-
0344069640
-
Dynamic changes of plasma acylcarnitine levels induced by fasting and sunflower oil challenge test in children
-
Costa C.C.G., de Almeida I.T., Jakobs C., Poll-The B.T., and Duran M. Dynamic changes of plasma acylcarnitine levels induced by fasting and sunflower oil challenge test in children. Pediatr Res 46 (1999) 440-444
-
(1999)
Pediatr Res
, vol.46
, pp. 440-444
-
-
Costa, C.C.G.1
de Almeida, I.T.2
Jakobs, C.3
Poll-The, B.T.4
Duran, M.5
-
30
-
-
0025107323
-
Brain and liver pathology in a patient with carnitine deficiency
-
Kimura S., and Amemiya F. Brain and liver pathology in a patient with carnitine deficiency. Brain Dev 12 (1990) 436-439
-
(1990)
Brain Dev
, vol.12
, pp. 436-439
-
-
Kimura, S.1
Amemiya, F.2
-
31
-
-
0037707488
-
Energy contribution of octanoate to intact rat brain metabolism measured by C-13 nuclear magnetic resonance spectroscopy
-
Ebert D., Haller R.G., and Walton M.E. Energy contribution of octanoate to intact rat brain metabolism measured by C-13 nuclear magnetic resonance spectroscopy. J Neurosci 23 (2003) 5928-5935
-
(2003)
J Neurosci
, vol.23
, pp. 5928-5935
-
-
Ebert, D.1
Haller, R.G.2
Walton, M.E.3
-
32
-
-
0029950626
-
Carnitine - a known compound, a novel function in neural cells
-
Nalecz K.A., and Nalecz M.J. Carnitine - a known compound, a novel function in neural cells. Acta Neurobiol Exp [Warsz] 56 (1996) 597-609
-
(1996)
Acta Neurobiol Exp [Warsz]
, vol.56
, pp. 597-609
-
-
Nalecz, K.A.1
Nalecz, M.J.2
-
33
-
-
0020376142
-
Carnitine, carnitine acyltransferases, and rat brain function
-
Bresolin N., Freddo L., Vergani L., and Angelini C. Carnitine, carnitine acyltransferases, and rat brain function. Exp Neurol 78 (1982) 285-292
-
(1982)
Exp Neurol
, vol.78
, pp. 285-292
-
-
Bresolin, N.1
Freddo, L.2
Vergani, L.3
Angelini, C.4
-
34
-
-
0019310364
-
Tissue distribution of carnitine biosynthetic enzymes in man
-
Rebouche C.J., and Engel A.J. Tissue distribution of carnitine biosynthetic enzymes in man. Biochim Biophys Acta 630 (1980) 22-29
-
(1980)
Biochim Biophys Acta
, vol.630
, pp. 22-29
-
-
Rebouche, C.J.1
Engel, A.J.2
-
35
-
-
0021907294
-
Carnitine acyltransferase activities in rat brain mitochondria
-
Bird M.I., Munday L.A., Saggerson E.D., and Clark J.B. Carnitine acyltransferase activities in rat brain mitochondria. Biochem J 226 (1985) 323-330
-
(1985)
Biochem J
, vol.226
, pp. 323-330
-
-
Bird, M.I.1
Munday, L.A.2
Saggerson, E.D.3
Clark, J.B.4
-
36
-
-
0035209172
-
Functional relevance of carnitine transporter OCTN2 to brain distribution of l-carnitine and acetyl-l-carnitine across the blood-brain barrier
-
Kido Y., Tamai I., Ohnari A., et al. Functional relevance of carnitine transporter OCTN2 to brain distribution of l-carnitine and acetyl-l-carnitine across the blood-brain barrier. J Neurochem 79 (2001) 959-969
-
(2001)
J Neurochem
, vol.79
, pp. 959-969
-
-
Kido, Y.1
Tamai, I.2
Ohnari, A.3
-
37
-
-
0035870096
-
--coupled active transport of carnitine by the amino acid transporter ATB[0, +] from mouse colon expressed in HRPE cells and Xenopus oocytes
-
--coupled active transport of carnitine by the amino acid transporter ATB[0, +] from mouse colon expressed in HRPE cells and Xenopus oocytes. J Physiol-London 532 (2001) 297-304
-
(2001)
J Physiol-London
, vol.532
, pp. 297-304
-
-
Nakanishi, T.1
Hatanaka, T.2
Huang, T.3
-
38
-
-
0033588179
-
Cloning and functional expression of a human Na[+] and Cl[-]-dependent neutral and cationic amino acid transporter B[0, +]
-
Sloan J.L., and Mager S. Cloning and functional expression of a human Na[+] and Cl[-]-dependent neutral and cationic amino acid transporter B[0, +]. J Biol Chem 274 (1999) 23740-23745
-
(1999)
J Biol Chem
, vol.274
, pp. 23740-23745
-
-
Sloan, J.L.1
Mager, S.2
-
40
-
-
37249013935
-
Localization of organic cation/carnitine transporter [OCTN2] in cells forming the blood-brain barrier
-
Miecz D., Januszewicz E., Czeredys M., et al. Localization of organic cation/carnitine transporter [OCTN2] in cells forming the blood-brain barrier. J Neurochem 104 (2008) 113-123
-
(2008)
J Neurochem
, vol.104
, pp. 113-123
-
-
Miecz, D.1
Januszewicz, E.2
Czeredys, M.3
-
41
-
-
0029010899
-
Effect of externally added carnitine on the synthesis of acetylcholine in rat cerebral cortex cells
-
Wawrzenczyk A., Nalecz K.A., and Nalecz M.J. Effect of externally added carnitine on the synthesis of acetylcholine in rat cerebral cortex cells. Neurochem Int 26 (1995) 635-641
-
(1995)
Neurochem Int
, vol.26
, pp. 635-641
-
-
Wawrzenczyk, A.1
Nalecz, K.A.2
Nalecz, M.J.3
-
43
-
-
37349065551
-
Expression patterns of the organic cation/carnitine transporter family in adult murine brain
-
Lamhonwah A.M., Hawkins C.E., Tam C., Wong J., Mai L., and Tein I. Expression patterns of the organic cation/carnitine transporter family in adult murine brain. Brain Dev 30 (2008) 31-42
-
(2008)
Brain Dev
, vol.30
, pp. 31-42
-
-
Lamhonwah, A.M.1
Hawkins, C.E.2
Tam, C.3
Wong, J.4
Mai, L.5
Tein, I.6
-
44
-
-
0028107682
-
Neuroprotective activity of acetyl-l-carnitine: Studies in vitro
-
Forloni G., Angeretti N., and Smiroldo S. Neuroprotective activity of acetyl-l-carnitine: Studies in vitro. J Neurosci Res 37 (1994) 92-96
-
(1994)
J Neurosci Res
, vol.37
, pp. 92-96
-
-
Forloni, G.1
Angeretti, N.2
Smiroldo, S.3
-
45
-
-
0026002366
-
Long-term acetyl-l-carnitine treatment in Alzheimer's disease
-
Spagnoli A., Lucca U., Menasce G., et al. Long-term acetyl-l-carnitine treatment in Alzheimer's disease. Neurology 41 (1991) 1726-1732
-
(1991)
Neurology
, vol.41
, pp. 1726-1732
-
-
Spagnoli, A.1
Lucca, U.2
Menasce, G.3
-
46
-
-
0018580076
-
In vitro effects of palmitylcarnitine on cardiac plasma membrane Na, K-ATPase, and sarcoplasmic reticulum Ca2+ ATPase and Ca2+ transport
-
Adams R.J., Cohen D.W., Gupte S., et al. In vitro effects of palmitylcarnitine on cardiac plasma membrane Na, K-ATPase, and sarcoplasmic reticulum Ca2+ ATPase and Ca2+ transport. J Biol Chem 254 (1979) 12404-12410
-
(1979)
J Biol Chem
, vol.254
, pp. 12404-12410
-
-
Adams, R.J.1
Cohen, D.W.2
Gupte, S.3
-
47
-
-
0034494263
-
Alteration of the membrane lipid environment by l-palmitoylcarnitine modulates K[ATP] channels in guinea-pig ventricular myocytes
-
Haruna T., Horie M., Takano M., et al. Alteration of the membrane lipid environment by l-palmitoylcarnitine modulates K[ATP] channels in guinea-pig ventricular myocytes. Pflugers Arch 441 (2000) 200-207
-
(2000)
Pflugers Arch
, vol.441
, pp. 200-207
-
-
Haruna, T.1
Horie, M.2
Takano, M.3
-
48
-
-
0030581644
-
Activation and inhibition of reconstituted cardiac l-type calcium channels by palmitoyl-l-carnitine
-
Liu Q.Y., and Rosenberg R.L. Activation and inhibition of reconstituted cardiac l-type calcium channels by palmitoyl-l-carnitine. Biochem Biophys Res Commun 228 (1996) 252-258
-
(1996)
Biochem Biophys Res Commun
, vol.228
, pp. 252-258
-
-
Liu, Q.Y.1
Rosenberg, R.L.2
-
49
-
-
0028911037
-
Palmitoyl-l-carnitine acts like ouabain on voltage, current, and contraction in guinea pig ventricular cells
-
Shen J.B., and Pappano A.J. Palmitoyl-l-carnitine acts like ouabain on voltage, current, and contraction in guinea pig ventricular cells. Am J Physiol Heart Circ Physiol 268 (1995) H1027-H1036
-
(1995)
Am J Physiol Heart Circ Physiol
, vol.268
-
-
Shen, J.B.1
Pappano, A.J.2
-
50
-
-
0026622948
-
Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes
-
Arduini A., Mancinelli G., Radatti G.L., Dottori S., Molajoni F., and Ramsay R.R. Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes. J Biol Chem 267 (1992) 12673-12681
-
(1992)
J Biol Chem
, vol.267
, pp. 12673-12681
-
-
Arduini, A.1
Mancinelli, G.2
Radatti, G.L.3
Dottori, S.4
Molajoni, F.5
Ramsay, R.R.6
-
51
-
-
0028331437
-
Evidence for the involvement of carnitine-dependent long-chain acyltransferases in neuronal triglyceride and phospholipid fatty acid turnover
-
Arduini A., Denisova N., Virmani A., Avrova N., Federici G., and Arrigoni-Martelli E. Evidence for the involvement of carnitine-dependent long-chain acyltransferases in neuronal triglyceride and phospholipid fatty acid turnover. J Neurochem 62 (1994) 1530-1538
-
(1994)
J Neurochem
, vol.62
, pp. 1530-1538
-
-
Arduini, A.1
Denisova, N.2
Virmani, A.3
Avrova, N.4
Federici, G.5
Arrigoni-Martelli, E.6
-
52
-
-
0037375697
-
Palmitoylcarnitine modulates palmitoylatjion of proteins: implication for differentiation of neural cells
-
Szczepankowska D., and Nalecz K.A. Palmitoylcarnitine modulates palmitoylatjion of proteins: implication for differentiation of neural cells. Neurochem Res 28 (2003) 645-651
-
(2003)
Neurochem Res
, vol.28
, pp. 645-651
-
-
Szczepankowska, D.1
Nalecz, K.A.2
-
53
-
-
0036421318
-
A novel brain-expressed protein related to carnitine palmitoyltransferase I
-
Price N.T., van der Leij F.R., Jackson V.N., et al. A novel brain-expressed protein related to carnitine palmitoyltransferase I. Genomics 80 (2002) 433-442
-
(2002)
Genomics
, vol.80
, pp. 433-442
-
-
Price, N.T.1
van der Leij, F.R.2
Jackson, V.N.3
-
54
-
-
42549146972
-
Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight
-
Wolfgang M.J., Cha S.H., Millington D.S., et al. Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight. J Neurochem 105 (2008) 1550-1559
-
(2008)
J Neurochem
, vol.105
, pp. 1550-1559
-
-
Wolfgang, M.J.1
Cha, S.H.2
Millington, D.S.3
-
55
-
-
43749088942
-
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
-
Sierra A.Y., Gratacos E., Carrasco P., et al. CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity. J Biol Chem 283 (2008) 6878-6885
-
(2008)
J Biol Chem
, vol.283
, pp. 6878-6885
-
-
Sierra, A.Y.1
Gratacos, E.2
Carrasco, P.3
-
56
-
-
0034726059
-
Regulation of the activity of caspases by l-carnitine and palmitoylcarnitine
-
Mutomba M.C., Yuan H., Konyavko M., et al. Regulation of the activity of caspases by l-carnitine and palmitoylcarnitine. FEBS Lett 478 (2000) 19-25
-
(2000)
FEBS Lett
, vol.478
, pp. 19-25
-
-
Mutomba, M.C.1
Yuan, H.2
Konyavko, M.3
-
57
-
-
0043066788
-
A novel action of palmitoyl-l-carnitine in human vascular endothelial cells
-
Muraki K., and Imaizumi Y. A novel action of palmitoyl-l-carnitine in human vascular endothelial cells. J Pharmacol Sci 92 (2003) 252-258
-
(2003)
J Pharmacol Sci
, vol.92
, pp. 252-258
-
-
Muraki, K.1
Imaizumi, Y.2
-
58
-
-
0031456381
-
Effect of palmitoylcarnitine on the cellular differentiation, proliferation and protein kinase C activity in neuroblastoma nb-2a cells
-
Nalecz K.A., Mroczkowska J.E., Berent U., and Nalecz M.J. Effect of palmitoylcarnitine on the cellular differentiation, proliferation and protein kinase C activity in neuroblastoma nb-2a cells. Acta Neurobiol Exp [Warsz] 57 (1997) 263-274
-
(1997)
Acta Neurobiol Exp [Warsz]
, vol.57
, pp. 263-274
-
-
Nalecz, K.A.1
Mroczkowska, J.E.2
Berent, U.3
Nalecz, M.J.4
-
59
-
-
0037210368
-
Interaction of palmitoylcarnitine with protein kinase C in neuroblastoma NB-2a cells
-
Sobiesiak-Mirska J., Nalecz M.J., and Nalecz K.A. Interaction of palmitoylcarnitine with protein kinase C in neuroblastoma NB-2a cells. Neurochem Int 42 (2003) 45-55
-
(2003)
Neurochem Int
, vol.42
, pp. 45-55
-
-
Sobiesiak-Mirska, J.1
Nalecz, M.J.2
Nalecz, K.A.3
-
60
-
-
0031897255
-
Accumulation of palmitoylcarnitine in neuroblastoma NB-2a cells affects the expression, phosphorylation and localization of B-50 protein
-
Mizgalska J.A., Berent U., Mac M., et al. Accumulation of palmitoylcarnitine in neuroblastoma NB-2a cells affects the expression, phosphorylation and localization of B-50 protein. Neurosci Res Commun 22 (1998) 73-82
-
(1998)
Neurosci Res Commun
, vol.22
, pp. 73-82
-
-
Mizgalska, J.A.1
Berent, U.2
Mac, M.3
-
61
-
-
0020423164
-
The distribution and role of carnitine in the mammalian brain
-
Shug A.L., Schmidt M.J., Golden G.T., and Fariello R.G. The distribution and role of carnitine in the mammalian brain. Life Sci 31 (1982) 2869-2874
-
(1982)
Life Sci
, vol.31
, pp. 2869-2874
-
-
Shug, A.L.1
Schmidt, M.J.2
Golden, G.T.3
Fariello, R.G.4
-
62
-
-
0026516050
-
Pharmacokinetics of IV and oral acetyl-l-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type
-
Parnetti L., Gaiti A., Mecocci P., Cadini D., and Senin U. Pharmacokinetics of IV and oral acetyl-l-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type. Eur J Clin Pharmacol 42 (1992) 89-93
-
(1992)
Eur J Clin Pharmacol
, vol.42
, pp. 89-93
-
-
Parnetti, L.1
Gaiti, A.2
Mecocci, P.3
Cadini, D.4
Senin, U.5
-
63
-
-
0032527045
-
Acetyl-l-carnitine modulates glucose metabolism and stimulates glycogen synthesis in rat brain
-
Aureli T., Di Cocco M.E., Pucetti C., et al. Acetyl-l-carnitine modulates glucose metabolism and stimulates glycogen synthesis in rat brain. Brain Res 796 (1998) 75-81
-
(1998)
Brain Res
, vol.796
, pp. 75-81
-
-
Aureli, T.1
Di Cocco, M.E.2
Pucetti, C.3
-
64
-
-
0031769321
-
Action of l-acetylcarnitine on different cerebral mitochondrial populations from cerebral cortex
-
Gorini A., D'Angelo A., and Villa R.F. Action of l-acetylcarnitine on different cerebral mitochondrial populations from cerebral cortex. Neurochem Res 23 (1998) 1485-1491
-
(1998)
Neurochem Res
, vol.23
, pp. 1485-1491
-
-
Gorini, A.1
D'Angelo, A.2
Villa, R.F.3
-
65
-
-
30544442097
-
Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes
-
Calabrese V., Stella A.M.G., Calvani M., and Butterfield D.A. Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes. J Nutr Biochem 17 (2006) 73-88
-
(2006)
J Nutr Biochem
, vol.17
, pp. 73-88
-
-
Calabrese, V.1
Stella, A.M.G.2
Calvani, M.3
Butterfield, D.A.4
-
66
-
-
71749114771
-
-
New York Acad Sciences, New York
-
Zanelli S.A., Solenski N.J., Rosenthal R.E., and Fiskum G. Mechanisms of ischemic neuroprotection by acetyl-l-carnitine (2005), New York Acad Sciences, New York
-
(2005)
Mechanisms of ischemic neuroprotection by acetyl-l-carnitine
-
-
Zanelli, S.A.1
Solenski, N.J.2
Rosenthal, R.E.3
Fiskum, G.4
-
67
-
-
4444289045
-
Role of carnitine esters in brain neuropathology
-
Virmani A., and Binienda Z. Role of carnitine esters in brain neuropathology. Mol Aspects Med 25 (2004) 533-549
-
(2004)
Mol Aspects Med
, vol.25
, pp. 533-549
-
-
Virmani, A.1
Binienda, Z.2
-
68
-
-
0033653231
-
Acetyl-l-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression
-
Pettegrew J.W., Levine J., and McClure R.J. Acetyl-l-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. Mol Psychiatry 5 (2000) 616-632
-
(2000)
Mol Psychiatry
, vol.5
, pp. 616-632
-
-
Pettegrew, J.W.1
Levine, J.2
McClure, R.J.3
-
69
-
-
0022475988
-
Entry of acetyl-l-carnitine into biosynthetic pathways
-
Farrell S., Vogel J., and Bieber L.L. Entry of acetyl-l-carnitine into biosynthetic pathways. Biochim Biophys Acta 876 (1986) 175-177
-
(1986)
Biochim Biophys Acta
, vol.876
, pp. 175-177
-
-
Farrell, S.1
Vogel, J.2
Bieber, L.L.3
-
70
-
-
0031797265
-
Role of acetyl-l-carnitine in rat brain lipogenesis: Implications for polyunsaturated fatty acid biosynthesis
-
Ricciolini R., Scalibastri M., Kelleher J.K., Carminati P., Calvani M., and Arduini A. Role of acetyl-l-carnitine in rat brain lipogenesis: Implications for polyunsaturated fatty acid biosynthesis. J Neurochem 71 (1998) 2510-2517
-
(1998)
J Neurochem
, vol.71
, pp. 2510-2517
-
-
Ricciolini, R.1
Scalibastri, M.2
Kelleher, J.K.3
Carminati, P.4
Calvani, M.5
Arduini, A.6
-
71
-
-
0028891690
-
Clinical and neurochemical effects of acetyl-l-carnitine in Alzheimer's disease
-
Pettegrew J.W., Klunk W.E., Panchalingam K., Kanfer J.N., and McClure R.J. Clinical and neurochemical effects of acetyl-l-carnitine in Alzheimer's disease. Neurobiol Aging 16 (1995) 1-4
-
(1995)
Neurobiol Aging
, vol.16
, pp. 1-4
-
-
Pettegrew, J.W.1
Klunk, W.E.2
Panchalingam, K.3
Kanfer, J.N.4
McClure, R.J.5
-
72
-
-
0025026205
-
Et al. Aging brain: effect of acetyl-l-carnitine treatment on rat brain energy and phospholipid metabolism. A study by 31P and 1H NMR spectroscopy
-
Aureli T., Miccheli A., and Ricciolini R. Et al. Aging brain: effect of acetyl-l-carnitine treatment on rat brain energy and phospholipid metabolism. A study by 31P and 1H NMR spectroscopy. Brain Res 526 (1990) 108-112
-
(1990)
Brain Res
, vol.526
, pp. 108-112
-
-
Aureli, T.1
Miccheli, A.2
Ricciolini, R.3
-
73
-
-
0028347621
-
Effect of acetyl-l-carnitine on recovery of brain phosphorus metabolites and lactic acid level during reperfusion after cerebral ischemia in the rat-Study by 13P- and 1H-NMR spectroscopy
-
Aureli T., Miccheli A., Di Cocco M.E., et al. Effect of acetyl-l-carnitine on recovery of brain phosphorus metabolites and lactic acid level during reperfusion after cerebral ischemia in the rat-Study by 13P- and 1H-NMR spectroscopy. Brain Res 643 (1994) 92-99
-
(1994)
Brain Res
, vol.643
, pp. 92-99
-
-
Aureli, T.1
Miccheli, A.2
Di Cocco, M.E.3
-
74
-
-
0026667916
-
Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-l-carnitine
-
Rosenthal R.E., Williams R., Bogaert Y.E., Getson P.R., and Fiskum G. Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-l-carnitine. Stroke 23 (1992) 1312-1318
-
(1992)
Stroke
, vol.23
, pp. 1312-1318
-
-
Rosenthal, R.E.1
Williams, R.2
Bogaert, Y.E.3
Getson, P.R.4
Fiskum, G.5
-
76
-
-
0032482999
-
Acetyl-l-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity
-
Hagen T.M., Ingersoll R.T., Wehr C.M., et al. Acetyl-l-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Proc Natl Acad Sci USA 95 (1998) 9562-9566
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9562-9566
-
-
Hagen, T.M.1
Ingersoll, R.T.2
Wehr, C.M.3
-
77
-
-
10644232862
-
Delaying the mitochondrial decay of aging with acetylcarnitine
-
Ames B.N., and Liu J. Delaying the mitochondrial decay of aging with acetylcarnitine. Ann NY Acad Sci 1033 (2004) 108-116
-
(2004)
Ann NY Acad Sci
, vol.1033
, pp. 108-116
-
-
Ames, B.N.1
Liu, J.2
-
78
-
-
0034062617
-
Effect of long-term feeding with acetyl-l-carnitine on the age-related changes in rat brain lipid composition: a study by P-31 NMR spectroscopy
-
Aureli T., Di Cocco M.E., Capuani G., et al. Effect of long-term feeding with acetyl-l-carnitine on the age-related changes in rat brain lipid composition: a study by P-31 NMR spectroscopy. Neurochem Res 25 (2000) 395-399
-
(2000)
Neurochem Res
, vol.25
, pp. 395-399
-
-
Aureli, T.1
Di Cocco, M.E.2
Capuani, G.3
-
79
-
-
0037133304
-
Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
-
Hagen T.M., Liu J.K., Lykkesfeldt J., et al. Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA 99 (2002) 1870-1875
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1870-1875
-
-
Hagen, T.M.1
Liu, J.K.2
Lykkesfeldt, J.3
-
80
-
-
62349088898
-
Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-l-carnitine
-
Long J.G., Gao F., Tong L.Q., Cotman C.W., Ames B.N., and Liu J.K. Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-l-carnitine. Neurochem Res 34 (2009) 755-763
-
(2009)
Neurochem Res
, vol.34
, pp. 755-763
-
-
Long, J.G.1
Gao, F.2
Tong, L.Q.3
Cotman, C.W.4
Ames, B.N.5
Liu, J.K.6
-
81
-
-
61349084847
-
Neuronal mitochondrial amelioration by feeding acetyl-l-carnitine and lipoic acid to aged rats
-
Aliev G., Liu J., Shenk J.C., et al. Neuronal mitochondrial amelioration by feeding acetyl-l-carnitine and lipoic acid to aged rats. J Cell Mol Med 13 (2009) 320-333
-
(2009)
J Cell Mol Med
, vol.13
, pp. 320-333
-
-
Aliev, G.1
Liu, J.2
Shenk, J.C.3
-
82
-
-
33748965936
-
Acetyl-l-carnitine feeding to unloaded rats triggers in soleus muscle the coordinated expression of genes involved in mitochondrial biogenesis
-
Cassano P., Sciancalepore A.G., Pesce V., et al. Acetyl-l-carnitine feeding to unloaded rats triggers in soleus muscle the coordinated expression of genes involved in mitochondrial biogenesis. Biochim Biophys Acta-Bioenerg 1757 (2006) 1421-1428
-
(2006)
Biochim Biophys Acta-Bioenerg
, vol.1757
, pp. 1421-1428
-
-
Cassano, P.1
Sciancalepore, A.G.2
Pesce, V.3
-
83
-
-
0027263979
-
Behavioural and biochemical effects of acute central metabolic inhibition: effects of acetyl-l-carnitine
-
Blokland A., Bothmer J., Honig W., and Jolles J. Behavioural and biochemical effects of acute central metabolic inhibition: effects of acetyl-l-carnitine. Eur J Pharmacol 235 (1993) 275-281
-
(1993)
Eur J Pharmacol
, vol.235
, pp. 275-281
-
-
Blokland, A.1
Bothmer, J.2
Honig, W.3
Jolles, J.4
-
84
-
-
0029551141
-
Protective actions of l-carnitine and acetyl-l-carnitine on the neurotoxicity evoked by mitochondrial uncoupling or inhibitors
-
Virmani M.A., Biselli R., Spadoni A., et al. Protective actions of l-carnitine and acetyl-l-carnitine on the neurotoxicity evoked by mitochondrial uncoupling or inhibitors. Pharmacol Res 32 (1995) 383-389
-
(1995)
Pharmacol Res
, vol.32
, pp. 383-389
-
-
Virmani, M.A.1
Biselli, R.2
Spadoni, A.3
-
85
-
-
0034937436
-
The action of acetyl-l-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones
-
Virmani M.A., Caso V., Spadoni A., Rossi S., Russo F., and Gaetani F. The action of acetyl-l-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones. Neuroprotect Agents 939 (2001) 162-178
-
(2001)
Neuroprotect Agents
, vol.939
, pp. 162-178
-
-
Virmani, M.A.1
Caso, V.2
Spadoni, A.3
Rossi, S.4
Russo, F.5
Gaetani, F.6
-
86
-
-
34247330919
-
Modulation of inflammation in brain: a matter of fat
-
Farooqui A.A., Horrocks L.A., and Farooqui T. Modulation of inflammation in brain: a matter of fat. J Neurochem 101 (2007) 577-599
-
(2007)
J Neurochem
, vol.101
, pp. 577-599
-
-
Farooqui, A.A.1
Horrocks, L.A.2
Farooqui, T.3
-
87
-
-
0034625739
-
Phospholipid composition and levels are altered in down syndrome brain
-
Murphy E.J., Schapiro M.B., Rapoport S.I., and Shetty H.U. Phospholipid composition and levels are altered in down syndrome brain. Brain Res 867 (2000) 9-18
-
(2000)
Brain Res
, vol.867
, pp. 9-18
-
-
Murphy, E.J.1
Schapiro, M.B.2
Rapoport, S.I.3
Shetty, H.U.4
-
88
-
-
0030893109
-
Membrane phospholipid alterations in Alzheimer's disease: deficiency of ethanolamine plasmalogens
-
Farooqui A.A., Rapoport S.I., and Horrocks L.A. Membrane phospholipid alterations in Alzheimer's disease: deficiency of ethanolamine plasmalogens. Neurochem Res 22 (1997) 523-527
-
(1997)
Neurochem Res
, vol.22
, pp. 523-527
-
-
Farooqui, A.A.1
Rapoport, S.I.2
Horrocks, L.A.3
-
89
-
-
0025913434
-
Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease
-
Söderberg M., Edlund C., Kristensson K., and Dallner G. Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease. Lipids 26 (1991) 421-425
-
(1991)
Lipids
, vol.26
, pp. 421-425
-
-
Söderberg, M.1
Edlund, C.2
Kristensson, K.3
Dallner, G.4
-
90
-
-
0034793503
-
Impaired phospholipid-related signal transduction in advanced Huntington's disease
-
Puri B.K. Impaired phospholipid-related signal transduction in advanced Huntington's disease. Exp Physiol 86 (2001) 683-685
-
(2001)
Exp Physiol
, vol.86
, pp. 683-685
-
-
Puri, B.K.1
-
91
-
-
0031041126
-
On the molecular etiology of decreased arachidonic [20:4n-6], docosapentaenoic [22:5n-6] and docosahexaenoic [22:6n-3] acids in Zellweger syndrome and other peroxisomal disorders
-
Infante J.P., and Huszagh V.A. On the molecular etiology of decreased arachidonic [20:4n-6], docosapentaenoic [22:5n-6] and docosahexaenoic [22:6n-3] acids in Zellweger syndrome and other peroxisomal disorders. Mol Cell Biochem 168 (1997) 101-115
-
(1997)
Mol Cell Biochem
, vol.168
, pp. 101-115
-
-
Infante, J.P.1
Huszagh, V.A.2
-
92
-
-
0032987352
-
A function for the vitamin E metabolite alpha-tocopherol quinone as an essential enzyme cofactor for the mitochondrial fatty acid desaturases
-
Infante J.P. A function for the vitamin E metabolite alpha-tocopherol quinone as an essential enzyme cofactor for the mitochondrial fatty acid desaturases. FEBS Lett 446 (1999) 1-5
-
(1999)
FEBS Lett
, vol.446
, pp. 1-5
-
-
Infante, J.P.1
-
93
-
-
0033955887
-
Secondary carnitine deficiency and impaired docosahexaenoic [22:6n-3] acid synthesis: a common denominator in the pathophysiology of diseases of oxidative phosphorylation and beta-oxidation
-
Infante J.P., and Huszagh V.A. Secondary carnitine deficiency and impaired docosahexaenoic [22:6n-3] acid synthesis: a common denominator in the pathophysiology of diseases of oxidative phosphorylation and beta-oxidation. FEBS Lett 468 (2000) 1-5
-
(2000)
FEBS Lett
, vol.468
, pp. 1-5
-
-
Infante, J.P.1
Huszagh, V.A.2
-
94
-
-
1842453667
-
Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function
-
Horrocks L.A., and Farooqui A.A. Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function. Prostag Leukotr Essent Fatty Acids 70 (2004) 361-372
-
(2004)
Prostag Leukotr Essent Fatty Acids
, vol.70
, pp. 361-372
-
-
Horrocks, L.A.1
Farooqui, A.A.2
-
95
-
-
0942298545
-
Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice
-
Hinerfeld D., Traini M.D., Weinberger R.P., et al. Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. J Neurochem 88 (2004) 657-667
-
(2004)
J Neurochem
, vol.88
, pp. 657-667
-
-
Hinerfeld, D.1
Traini, M.D.2
Weinberger, R.P.3
-
96
-
-
47149086766
-
Acetyl-l-Carnitine selectively prevents post-ischemic LTP via a possible action on mitochondrial energy metabolism
-
Bagetta V., Barone I., Ghiglieri V., et al. Acetyl-l-Carnitine selectively prevents post-ischemic LTP via a possible action on mitochondrial energy metabolism. Neuropharmacology 55 (2008) 223-229
-
(2008)
Neuropharmacology
, vol.55
, pp. 223-229
-
-
Bagetta, V.1
Barone, I.2
Ghiglieri, V.3
-
97
-
-
58149463913
-
Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain
-
Alves E., Binienda Z., Carvalho F., et al. Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain. Neuroscience 158 (2009) 514-523
-
(2009)
Neuroscience
, vol.158
, pp. 514-523
-
-
Alves, E.1
Binienda, Z.2
Carvalho, F.3
-
98
-
-
10444276598
-
Role of mitochondrial dysfunction in neurotoxicity of MPP+ - Partial protection of PC12 cells by acetyl-l-carnitine
-
Virmani A, Gaetani F, Binienda Z, Xu A, Duhart H, Ali SF. Role of mitochondrial dysfunction in neurotoxicity of MPP+ - Partial protection of PC12 cells by acetyl-l-carnitine. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity 2004;1025:267-73.
-
(2004)
Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity
, vol.1025
, pp. 267-273
-
-
Virmani, A.1
Gaetani, F.2
Binienda, Z.3
Xu, A.4
Duhart, H.5
Ali, S.F.6
-
100
-
-
0038433337
-
Acetyl-l-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells
-
Mazzio E., Yoon K.J., and Soliman K.F.A. Acetyl-l-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. Biochem Pharmacol 66 (2003) 297-306
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 297-306
-
-
Mazzio, E.1
Yoon, K.J.2
Soliman, K.F.A.3
-
101
-
-
0033396459
-
Protective effect of l-carnitine in the neurotoxicity induced by the mitochondrial inhibitor 3-nitropropionic acid [3-NPA]
-
Binienda Z., Johnson J.R., Tyler-Hashemi A.A., et al. Protective effect of l-carnitine in the neurotoxicity induced by the mitochondrial inhibitor 3-nitropropionic acid [3-NPA]. Neuroprotect Agents: Fourth Int Conf 890 (1999) 173-178
-
(1999)
Neuroprotect Agents: Fourth Int Conf
, vol.890
, pp. 173-178
-
-
Binienda, Z.1
Johnson, J.R.2
Tyler-Hashemi, A.A.3
-
102
-
-
0038389442
-
Neuroprotective effects of l-carnitine in induced mitochondrial dysfunction
-
Binienda Z.K. Neuroprotective effects of l-carnitine in induced mitochondrial dysfunction. Neuroprotect Agents 993 (2003) 289-295
-
(2003)
Neuroprotect Agents
, vol.993
, pp. 289-295
-
-
Binienda, Z.K.1
-
103
-
-
42449104975
-
Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l-carnitine
-
Silva-Adaya D., Perez-De La Cruz V., Herrera-Mundo M.N., et al. Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l-carnitine. J Neurochem 105 (2008) 677-689
-
(2008)
J Neurochem
, vol.105
, pp. 677-689
-
-
Silva-Adaya, D.1
Perez-De La Cruz, V.2
Herrera-Mundo, M.N.3
-
104
-
-
0033032999
-
Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia
-
Schapira A.H.V. Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia. Biochim Biophys Acta-Bioenerg 1410 (1999) 159-170
-
(1999)
Biochim Biophys Acta-Bioenerg
, vol.1410
, pp. 159-170
-
-
Schapira, A.H.V.1
-
105
-
-
4344617955
-
Neuroprotective effect of l-carnitine in the 3-nitropropionic acid [3-NPA]-evoked neurotoxicity in rats
-
Binienda Z., Virmani A., Przybyla-Zawislak B., and Schmued L. Neuroprotective effect of l-carnitine in the 3-nitropropionic acid [3-NPA]-evoked neurotoxicity in rats. Neurosci Lett 367 (2004) 264-267
-
(2004)
Neurosci Lett
, vol.367
, pp. 264-267
-
-
Binienda, Z.1
Virmani, A.2
Przybyla-Zawislak, B.3
Schmued, L.4
-
106
-
-
23644442534
-
l-carnitine inhibits hypoglycemia-induced brain damage in the rat
-
Hino K., Nishikawa M., Sato E., and Inoue M. l-carnitine inhibits hypoglycemia-induced brain damage in the rat. Brain Res 1053 (2005) 77-87
-
(2005)
Brain Res
, vol.1053
, pp. 77-87
-
-
Hino, K.1
Nishikawa, M.2
Sato, E.3
Inoue, M.4
-
107
-
-
0033525773
-
Mitochondrial diseases in man and mouse
-
Wallace D.C. Mitochondrial diseases in man and mouse. Science 283 (1999) 1482-1488
-
(1999)
Science
, vol.283
, pp. 1482-1488
-
-
Wallace, D.C.1
-
108
-
-
0031804542
-
Nuclear power and mitochondrial disease
-
DiMauro S., and Schon E.A. Nuclear power and mitochondrial disease. Nat Genet 19 (1998) 214-215
-
(1998)
Nat Genet
, vol.19
, pp. 214-215
-
-
DiMauro, S.1
Schon, E.A.2
-
109
-
-
0032924831
-
Neonatal presentations of mitochondrial metabolic disorders
-
Sue C.M., Hirano M., DiMauro S., and De Vivo D.C. Neonatal presentations of mitochondrial metabolic disorders. Semin Perinatol 23 (1999) 113-124
-
(1999)
Semin Perinatol
, vol.23
, pp. 113-124
-
-
Sue, C.M.1
Hirano, M.2
DiMauro, S.3
De Vivo, D.C.4
-
110
-
-
0023682615
-
The relationship between alpha-tocopherol and phospholipid fatty acids in rat liver subcellular membrane fractions
-
Buttriss J.L., and Diplock A.T. The relationship between alpha-tocopherol and phospholipid fatty acids in rat liver subcellular membrane fractions. Biochim Biophys Acta 962 (1988) 81-90
-
(1988)
Biochim Biophys Acta
, vol.962
, pp. 81-90
-
-
Buttriss, J.L.1
Diplock, A.T.2
-
111
-
-
0026009326
-
Hypothyroidism and thyroxin substitution affect the n-3 fatty acid composition of rat liver mitochondria
-
Raederstorff D., Meier C.A., Moser U., and Walter P. Hypothyroidism and thyroxin substitution affect the n-3 fatty acid composition of rat liver mitochondria. Lipids 26 (1991) 781-787
-
(1991)
Lipids
, vol.26
, pp. 781-787
-
-
Raederstorff, D.1
Meier, C.A.2
Moser, U.3
Walter, P.4
-
112
-
-
14144255699
-
Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: Involvement of the transcription factor Nrf2
-
Calabrese V., Ravagna A., Colombrita C., et al. Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: Involvement of the transcription factor Nrf2. J Neurosci Res 79 (2005) 509-521
-
(2005)
J Neurosci Res
, vol.79
, pp. 509-521
-
-
Calabrese, V.1
Ravagna, A.2
Colombrita, C.3
-
113
-
-
33646675336
-
Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function
-
Calabrese V., Colombrita C., Sultana R., et al. Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function. Antioxid Redox Signal 8 (2006) 404-416
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 404-416
-
-
Calabrese, V.1
Colombrita, C.2
Sultana, R.3
-
114
-
-
33646699107
-
Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by l-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress
-
Poon H.F., Calabrese V., Calvani M., and Butterfield D.A. Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by l-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress. Antioxid Redox Signal 8 (2006) 381-394
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 381-394
-
-
Poon, H.F.1
Calabrese, V.2
Calvani, M.3
Butterfield, D.A.4
-
115
-
-
33746468121
-
Acetyl-l-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease
-
Abdul H.M., Calabrese V., Calvani M., and Butterfield D.A. Acetyl-l-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. J Neurosci Res 84 (2006) 398-408
-
(2006)
J Neurosci Res
, vol.84
, pp. 398-408
-
-
Abdul, H.M.1
Calabrese, V.2
Calvani, M.3
Butterfield, D.A.4
-
116
-
-
33845933757
-
Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-l-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease
-
Abdul H.M., and Butterfield D.A. Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-l-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease. Free Radic Biol Med 42 (2007) 371-384
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 371-384
-
-
Abdul, H.M.1
Butterfield, D.A.2
-
117
-
-
0029004336
-
Acetyl-l-carnitine corrects the altered peripheral nerve function of experimental diabetes
-
Lowitt S., Malone J.I., Salem A.F., Korthals J., and Benford S. Acetyl-l-carnitine corrects the altered peripheral nerve function of experimental diabetes. Metabolism 44 (1995) 677-680
-
(1995)
Metabolism
, vol.44
, pp. 677-680
-
-
Lowitt, S.1
Malone, J.I.2
Salem, A.F.3
Korthals, J.4
Benford, S.5
-
118
-
-
10644223303
-
Comparison of the effects of l-carnitine and acetyl-l-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats
-
Liu J., Head E., Kuratsune H., Cotman C.W., and Ames B.N. Comparison of the effects of l-carnitine and acetyl-l-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Ann NY Acad Sci 1033 (2004) 117-131
-
(2004)
Ann NY Acad Sci
, vol.1033
, pp. 117-131
-
-
Liu, J.1
Head, E.2
Kuratsune, H.3
Cotman, C.W.4
Ames, B.N.5
-
119
-
-
0028887004
-
Effects of l-carnitine on serum triglyceride and cytokine levels in rat models of cachexia and septic shock
-
Winter B.K., Fiskum G., and Gallo L.L. Effects of l-carnitine on serum triglyceride and cytokine levels in rat models of cachexia and septic shock. Br J Cancer 72 (1995) 1173-1179
-
(1995)
Br J Cancer
, vol.72
, pp. 1173-1179
-
-
Winter, B.K.1
Fiskum, G.2
Gallo, L.L.3
-
120
-
-
0035501243
-
Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition
-
Furuno T., Kanno T., Arita K., et al. Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition. Biochem Pharmacol 62 (2001) 1037-1046
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 1037-1046
-
-
Furuno, T.1
Kanno, T.2
Arita, K.3
-
121
-
-
18844439697
-
Reduction of apoptosis through the mitochondrial pathway by the administration of acetyl-l-carnitine to mouse fibroblasts in culture
-
Pillich R.T., Scarsella G., and Risuleo G. Reduction of apoptosis through the mitochondrial pathway by the administration of acetyl-l-carnitine to mouse fibroblasts in culture. Exp Cell Res 306 (2005) 1-8
-
(2005)
Exp Cell Res
, vol.306
, pp. 1-8
-
-
Pillich, R.T.1
Scarsella, G.2
Risuleo, G.3
-
122
-
-
0033922436
-
Anti-apoptotic effect of acetyl-l-carnitine and l-carnitine in primary cultured neurons
-
Ishii T., Shimpo Y., Kinoshita K., and Kinoshita K. Anti-apoptotic effect of acetyl-l-carnitine and l-carnitine in primary cultured neurons. Jpn J Pharmacol 83 (2000) 119-124
-
(2000)
Jpn J Pharmacol
, vol.83
, pp. 119-124
-
-
Ishii, T.1
Shimpo, Y.2
Kinoshita, K.3
Kinoshita, K.4
-
123
-
-
52049105602
-
Acetyl-l-carnitine suppresses apoptosis of thioredoxin 2-deficient DT40 cells
-
Zhu X.P., Sato E.F., Wang Y., Nakamura H., Yodoi J., and Inoue M. Acetyl-l-carnitine suppresses apoptosis of thioredoxin 2-deficient DT40 cells. Arch Biochem Biophys 478 (2008) 154-160
-
(2008)
Arch Biochem Biophys
, vol.478
, pp. 154-160
-
-
Zhu, X.P.1
Sato, E.F.2
Wang, Y.3
Nakamura, H.4
Yodoi, J.5
Inoue, M.6
-
124
-
-
0002188416
-
Acetyl-l-carnitine: metabolism and applications in clinical practice
-
Furlong J.H. Acetyl-l-carnitine: metabolism and applications in clinical practice. Altern Med Rev 1 (1996) 85-93
-
(1996)
Altern Med Rev
, vol.1
, pp. 85-93
-
-
Furlong, J.H.1
-
125
-
-
0028814185
-
Effects of acetyl-l-carnitine treatment and stress exposure on the nerve growth factor receptor [p75NGFR] mRNA level in the central nervous system of aged rats
-
Foreman P.J., Perez-Polo J.R., Angelucci L., Ramacci M.T., and Taglialatela G. Effects of acetyl-l-carnitine treatment and stress exposure on the nerve growth factor receptor [p75NGFR] mRNA level in the central nervous system of aged rats. Prog Neuropsychopharmacol Biol Psychiat 19 (1995) 117-133
-
(1995)
Prog Neuropsychopharmacol Biol Psychiat
, vol.19
, pp. 117-133
-
-
Foreman, P.J.1
Perez-Polo, J.R.2
Angelucci, L.3
Ramacci, M.T.4
Taglialatela, G.5
-
126
-
-
0029986949
-
Primary preventive and secondary interventionary effects of acetyl-l-carnitine on diabetic neuropathy in the bio-breeding Worcester rat
-
Sima A.A.F., Ristic H., Merry A., et al. Primary preventive and secondary interventionary effects of acetyl-l-carnitine on diabetic neuropathy in the bio-breeding Worcester rat. J Clin Invest 97 (1996) 1900-1907
-
(1996)
J Clin Invest
, vol.97
, pp. 1900-1907
-
-
Sima, A.A.F.1
Ristic, H.2
Merry, A.3
-
127
-
-
0027935884
-
Acetyl-l-carnitine prevents age-dependent structural alterations in rat peripheral nerves and promotes regeneration following sciatic nerve injury in young and senescent rats
-
De Angelis C., Scarfò C., Falcinelli M., et al. Acetyl-l-carnitine prevents age-dependent structural alterations in rat peripheral nerves and promotes regeneration following sciatic nerve injury in young and senescent rats. Exp Neurol 128 (1994) 103-114
-
(1994)
Exp Neurol
, vol.128
, pp. 103-114
-
-
De Angelis, C.1
Scarfò, C.2
Falcinelli, M.3
-
128
-
-
0037031529
-
Acetyl-l-carnitine shows neuroprotective and neurotrophic activity in primary culture of rat embryo motoneurons
-
Bigini P., Larini S., Pasquali C., Muzio V., and Mennini T. Acetyl-l-carnitine shows neuroprotective and neurotrophic activity in primary culture of rat embryo motoneurons. Neurosci Lett 329 (2002) 334-338
-
(2002)
Neurosci Lett
, vol.329
, pp. 334-338
-
-
Bigini, P.1
Larini, S.2
Pasquali, C.3
Muzio, V.4
Mennini, T.5
-
129
-
-
56049128205
-
Role of acetyl-l-carnitine in the treatment of diabetic peripheral neuropathy
-
Evans J.D., Jacobs T.F., and Evans E.W. Role of acetyl-l-carnitine in the treatment of diabetic peripheral neuropathy. Ann Pharmacother 42 (2008) 1686-1691
-
(2008)
Ann Pharmacother
, vol.42
, pp. 1686-1691
-
-
Evans, J.D.1
Jacobs, T.F.2
Evans, E.W.3
-
130
-
-
4444225469
-
Acetyl-l-carnitine induces a sustained potentiation of the after hyperpolarization
-
Lombardo P., Scuri R., Cataldo E., et al. Acetyl-l-carnitine induces a sustained potentiation of the after hyperpolarization. Neuroscience 128 (2004) 293-303
-
(2004)
Neuroscience
, vol.128
, pp. 293-303
-
-
Lombardo, P.1
Scuri, R.2
Cataldo, E.3
-
131
-
-
0036429750
-
Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain
-
Kuratsune H., Yamaguti K., Lindh G., et al. Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain. Neuroimage 17 (2002) 1256-1265
-
(2002)
Neuroimage
, vol.17
, pp. 1256-1265
-
-
Kuratsune, H.1
Yamaguti, K.2
Lindh, G.3
-
132
-
-
38949140508
-
Acetyl-l-carnitine [ALC] treatment in elderly patients with fatigue
-
Malaguarnera M., Gargante M.P., Cristaldi E., et al. Acetyl-l-carnitine [ALC] treatment in elderly patients with fatigue. Arch Gerontol Geriatr 46 (2008) 181-190
-
(2008)
Arch Gerontol Geriatr
, vol.46
, pp. 181-190
-
-
Malaguarnera, M.1
Gargante, M.P.2
Cristaldi, E.3
-
133
-
-
0025284835
-
Acetyl-l-carnitine as a precursor of acetylcholine
-
White H.L., and Scates P.W. Acetyl-l-carnitine as a precursor of acetylcholine. Neurochem Res 15 (1990) 597-601
-
(1990)
Neurochem Res
, vol.15
, pp. 597-601
-
-
White, H.L.1
Scates, P.W.2
-
134
-
-
0035888178
-
Enhancement of learning capacity and cholinergic synaptic function by carnitine in aging rats
-
Ando S., Tadenuma T., Tanaka Y., et al. Enhancement of learning capacity and cholinergic synaptic function by carnitine in aging rats. J Neurosci Res 66 (2001) 266-271
-
(2001)
J Neurosci Res
, vol.66
, pp. 266-271
-
-
Ando, S.1
Tadenuma, T.2
Tanaka, Y.3
-
135
-
-
0024971871
-
Acetyl-l-carnitine enhances acetylcholine release in the striatum and hippocampus of awake freely moving rats
-
Imperato A., Ramacci M.T., and Angelucci L. Acetyl-l-carnitine enhances acetylcholine release in the striatum and hippocampus of awake freely moving rats. Neurosci Lett 107 (1989) 251-255
-
(1989)
Neurosci Lett
, vol.107
, pp. 251-255
-
-
Imperato, A.1
Ramacci, M.T.2
Angelucci, L.3
-
136
-
-
33646899542
-
Acetyl-l-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine
-
Picconi B., Barone I., Pisani A., et al. Acetyl-l-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine. Neuropharmacology 50 (2006) 917-923
-
(2006)
Neuropharmacology
, vol.50
, pp. 917-923
-
-
Picconi, B.1
Barone, I.2
Pisani, A.3
-
137
-
-
0027058797
-
Action of acetyl-l-carnitine in neurodegeneration and Alzheimer's disease
-
Calvani M., Carta A., Caruso G., Benedetti N., and Iannuccelli M. Action of acetyl-l-carnitine in neurodegeneration and Alzheimer's disease. Ann NY Acad Sci 663 (1992) 483-486
-
(1992)
Ann NY Acad Sci
, vol.663
, pp. 483-486
-
-
Calvani, M.1
Carta, A.2
Caruso, G.3
Benedetti, N.4
Iannuccelli, M.5
-
138
-
-
12244307865
-
Nerve growth factor and acetyl-l-carnitine evoked shifts in acetyl-CoA and cholinergic SN56 cell vulnerability to neurotoxic inputs
-
Szutowicz A., Bielarczyk H., Gul S., Zielinski P., Pawelczyk T., and Tomaszewicz M. Nerve growth factor and acetyl-l-carnitine evoked shifts in acetyl-CoA and cholinergic SN56 cell vulnerability to neurotoxic inputs. J Neurosci Res 79 (2005) 185-192
-
(2005)
J Neurosci Res
, vol.79
, pp. 185-192
-
-
Szutowicz, A.1
Bielarczyk, H.2
Gul, S.3
Zielinski, P.4
Pawelczyk, T.5
Tomaszewicz, M.6
-
139
-
-
71749107861
-
Chronicle of the development of an endogenous substance for dementia: acetyl-l-carnitine
-
Bes A. (Ed), John Libbey Eurotext
-
Calvani M., Lannuccelli M., Colasimone D., and Orfalian Z. Chronicle of the development of an endogenous substance for dementia: acetyl-l-carnitine. In: Bes A. (Ed). Senile dementias: early detection (1986), John Libbey Eurotext 394-400
-
(1986)
Senile dementias: early detection
, pp. 394-400
-
-
Calvani, M.1
Lannuccelli, M.2
Colasimone, D.3
Orfalian, Z.4
-
140
-
-
0022494388
-
Study of the efficacy and tolerability of l-acetylcarnitine therapy in the senile brain
-
Bonavita E. Study of the efficacy and tolerability of l-acetylcarnitine therapy in the senile brain. Int J Clin Pharmacol 24 (1986) 511-516
-
(1986)
Int J Clin Pharmacol
, vol.24
, pp. 511-516
-
-
Bonavita, E.1
-
141
-
-
0025720701
-
Effect of acetyl-l-carnitine on the dopaminergic system in aging brain
-
Sershen H., Harsing Jr. L.G., Banay-Schwartz M., Hashim A., Ramacci M.T., and Lajtha A. Effect of acetyl-l-carnitine on the dopaminergic system in aging brain. J Neurosci Res 30 (1991) 555-559
-
(1991)
J Neurosci Res
, vol.30
, pp. 555-559
-
-
Sershen, H.1
Harsing Jr., L.G.2
Banay-Schwartz, M.3
Hashim, A.4
Ramacci, M.T.5
Lajtha, A.6
-
142
-
-
0023747172
-
Systemic acetyl-l-carnitine elevates NigralLevels of glutathione and GABA
-
Fariello R.G., Ferraro T.N., Golden G.T., and DeMattei M. Systemic acetyl-l-carnitine elevates NigralLevels of glutathione and GABA. Life Sci 43 (1988) 289-292
-
(1988)
Life Sci
, vol.43
, pp. 289-292
-
-
Fariello, R.G.1
Ferraro, T.N.2
Golden, G.T.3
DeMattei, M.4
-
143
-
-
0028304915
-
GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?
-
Bahring R., Standhardt H., Martelli E.A., and Grantyn R. GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?. Eur J Neurosci 6 (1994) 1089-1099
-
(1994)
Eur J Neurosci
, vol.6
, pp. 1089-1099
-
-
Bahring, R.1
Standhardt, H.2
Martelli, E.A.3
Grantyn, R.4
-
144
-
-
0038095287
-
Role of acetyl-l-carnitine in the brain: revealed by bioradiography
-
Tanaka M., Nakamura F., Mizokawa S., Matsumura A., Matsumura K., and Watanabe Y. Role of acetyl-l-carnitine in the brain: revealed by bioradiography. Biochem Biophys Res Commun 306 (2003) 1064-1069
-
(2003)
Biochem Biophys Res Commun
, vol.306
, pp. 1064-1069
-
-
Tanaka, M.1
Nakamura, F.2
Mizokawa, S.3
Matsumura, A.4
Matsumura, K.5
Watanabe, Y.6
-
145
-
-
35848951163
-
Covalent modifications of histones during development and disease pathogenesis
-
Bhaumik S.R., Smith E., and Shilatifard A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14 (2007) 1008-1016
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1008-1016
-
-
Bhaumik, S.R.1
Smith, E.2
Shilatifard, A.3
-
146
-
-
8844286158
-
Identification of differentially expressed genes induced in the rat brain by acetyl-l-carnitine as evidenced by suppression subtractive hybridisation
-
Traina G., Valleggi S., Bernardi R., et al. Identification of differentially expressed genes induced in the rat brain by acetyl-l-carnitine as evidenced by suppression subtractive hybridisation. Mol Brain Res 132 (2004) 57-63
-
(2004)
Mol Brain Res
, vol.132
, pp. 57-63
-
-
Traina, G.1
Valleggi, S.2
Bernardi, R.3
-
147
-
-
66149090372
-
Cytoprotective effect of acetyl-l-carnitine evidenced by analysis of gene expression in the rat brain
-
Traina G., Federighi G., Brunelli M., and Scuri R. Cytoprotective effect of acetyl-l-carnitine evidenced by analysis of gene expression in the rat brain. Mol Neurobiol 39 (2009) 101-106
-
(2009)
Mol Neurobiol
, vol.39
, pp. 101-106
-
-
Traina, G.1
Federighi, G.2
Brunelli, M.3
Scuri, R.4
-
148
-
-
58149146893
-
In the rat brain acetyl-l-carnitine treatment modulates the expression of genes involved in neuronal ceroid lipofuscinosis
-
Traina G., Bernardi R., Cataldo E., Macchi M., Durante M., and Brunelli M. In the rat brain acetyl-l-carnitine treatment modulates the expression of genes involved in neuronal ceroid lipofuscinosis. Mol Neurobiol 38 (2008) 146-152
-
(2008)
Mol Neurobiol
, vol.38
, pp. 146-152
-
-
Traina, G.1
Bernardi, R.2
Cataldo, E.3
Macchi, M.4
Durante, M.5
Brunelli, M.6
-
149
-
-
56349128625
-
Up-regulation of kinesin light-chain 1 gene expression by acetyl-l-carnitine: therapeutic possibility in Alzheimer's disease
-
Traina G., Federighi G., and Brunelli M. Up-regulation of kinesin light-chain 1 gene expression by acetyl-l-carnitine: therapeutic possibility in Alzheimer's disease. Neurochem Int 53 (2008) 244-247
-
(2008)
Neurochem Int
, vol.53
, pp. 244-247
-
-
Traina, G.1
Federighi, G.2
Brunelli, M.3
-
150
-
-
0028175091
-
Raf meets Ras: completing the framework of a signal transduction pathway
-
Avruch J., Zhang X.F., and Kyriakis J.M. Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biochem Sci 19 (1994) 279-283
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 279-283
-
-
Avruch, J.1
Zhang, X.F.2
Kyriakis, J.M.3
-
151
-
-
0031841424
-
14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity
-
Thorson J.A., Yu L.W., Hsu A.L., et al. 14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity. Mol Cell Biol 18 (1998) 5229-5238
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5229-5238
-
-
Thorson, J.A.1
Yu, L.W.2
Hsu, A.L.3
-
152
-
-
0032585827
-
Increased levels of 14-3-3 gamma and epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome
-
Fountoulakis M., Cairns N., and Lubec G. Increased levels of 14-3-3 gamma and epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome. J Neural Transm Suppl 57 (1999) 323-335
-
(1999)
J Neural Transm Suppl
, vol.57
, pp. 323-335
-
-
Fountoulakis, M.1
Cairns, N.2
Lubec, G.3
-
153
-
-
39149104664
-
Gene-gene interaction between 14-3-3 zeta and butyrylcholinesterase modulates Alzheimer's disease risk
-
Mateo I., Llorca J., Infante J., Rodriguez-Rodriguez E., Berciano J., and Combarros O. Gene-gene interaction between 14-3-3 zeta and butyrylcholinesterase modulates Alzheimer's disease risk. Eur J Neurol 15 (2008) 219-222
-
(2008)
Eur J Neurol
, vol.15
, pp. 219-222
-
-
Mateo, I.1
Llorca, J.2
Infante, J.3
Rodriguez-Rodriguez, E.4
Berciano, J.5
Combarros, O.6
-
154
-
-
0028556714
-
Sequence analysis and mapping of a novel human mitochondrial ATP synthase subunit 9 cDNA [ATP5G3]
-
Yan W.L., Lerner T.J., Haines J.L., and Gusella J.F. Sequence analysis and mapping of a novel human mitochondrial ATP synthase subunit 9 cDNA [ATP5G3]. Genomics 24 (1994) 375-377
-
(1994)
Genomics
, vol.24
, pp. 375-377
-
-
Yan, W.L.1
Lerner, T.J.2
Haines, J.L.3
Gusella, J.F.4
-
155
-
-
1842525777
-
Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state
-
Calabrese V., Scapagnini G., Ravagna A., et al. Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state. Mech Ageing Dev 125 (2004) 325-335
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 325-335
-
-
Calabrese, V.1
Scapagnini, G.2
Ravagna, A.3
-
156
-
-
33746223208
-
Acetyl-l-carnitine up-regulates expression of voltage-dependent anion channel in the rat brain
-
Traina G., Bernardi R., Rizzo M., Calvani M., Durante M., and Brunelli M. Acetyl-l-carnitine up-regulates expression of voltage-dependent anion channel in the rat brain. Neurochem Int 48 (2006) 673-678
-
(2006)
Neurochem Int
, vol.48
, pp. 673-678
-
-
Traina, G.1
Bernardi, R.2
Rizzo, M.3
Calvani, M.4
Durante, M.5
Brunelli, M.6
-
157
-
-
4444315751
-
Carnitine: a nutritional, biosynthetic, and functional perspective
-
Steiber A., Kerner J., and Hoppel C.L. Carnitine: a nutritional, biosynthetic, and functional perspective. Mol Aspects Med 25 (2004) 455-473
-
(2004)
Mol Aspects Med
, vol.25
, pp. 455-473
-
-
Steiber, A.1
Kerner, J.2
Hoppel, C.L.3
-
158
-
-
18344385695
-
l-acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors
-
Chiechio S., Caricasole A., Barletta E., et al. l-acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. Mol Pharmacol 61 (2002) 989-996
-
(2002)
Mol Pharmacol
, vol.61
, pp. 989-996
-
-
Chiechio, S.1
Caricasole, A.2
Barletta, E.3
-
159
-
-
33747611426
-
Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappa B pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of l-acetylcarnitine
-
Chiechio S., Copani A., De Petris L., Morales M.E.P., Nicoletti F., and Gereau R.W. Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappa B pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of l-acetylcarnitine. Molecular Pain 2 (2006)
-
(2006)
Molecular Pain
, vol.2
-
-
Chiechio, S.1
Copani, A.2
De Petris, L.3
Morales, M.E.P.4
Nicoletti, F.5
Gereau, R.W.6
-
160
-
-
11044222846
-
Relative carnitine deficiency in autism
-
Filipek P.A., Juranek J., Nguyen M.T., Cummings C., and Gargus J.J. Relative carnitine deficiency in autism. J Autism Dev Disord 34 (2004) 615-623
-
(2004)
J Autism Dev Disord
, vol.34
, pp. 615-623
-
-
Filipek, P.A.1
Juranek, J.2
Nguyen, M.T.3
Cummings, C.4
Gargus, J.J.5
-
161
-
-
0037379314
-
Bioenergetic approaches for neuroprotection in Parkinson's disease
-
Beal M.F. Bioenergetic approaches for neuroprotection in Parkinson's disease. Ann Neurol 53 (2003) S39-S47
-
(2003)
Ann Neurol
, vol.53
-
-
Beal, M.F.1
-
162
-
-
33749067148
-
The effect of acetyl-l-carnitine administration on persons with Down syndrome
-
Pueschel S.M. The effect of acetyl-l-carnitine administration on persons with Down syndrome. Res Dev Disabil 27 (2006) 599-604
-
(2006)
Res Dev Disabil
, vol.27
, pp. 599-604
-
-
Pueschel, S.M.1
-
163
-
-
0142241197
-
l-carnitine reduces brain injury after hypoxia-ischemia in newborn rats
-
Wainwright M.S., Mannix M.K., Brown J., and Stumpf D.A. l-carnitine reduces brain injury after hypoxia-ischemia in newborn rats. Pediatr Res 54 (2003) 688-695
-
(2003)
Pediatr Res
, vol.54
, pp. 688-695
-
-
Wainwright, M.S.1
Mannix, M.K.2
Brown, J.3
Stumpf, D.A.4
-
164
-
-
0025050646
-
l-acetyl-carnitine in Huntington's disease: double-blind placebo controlled crossover study of drug effects on movement disorder and dementia
-
Goety C.G., Tanner C.M., Cohen J.A., et al. l-acetyl-carnitine in Huntington's disease: double-blind placebo controlled crossover study of drug effects on movement disorder and dementia. Mov Disord 5 (1990) 263-265
-
(1990)
Mov Disord
, vol.5
, pp. 263-265
-
-
Goety, C.G.1
Tanner, C.M.2
Cohen, J.A.3
-
165
-
-
0034004462
-
Double-blind, crossover, placebo-controlled clinical trial with l-acetylcarnitine in patients with degenerative cerebellar ataxia
-
Sorbi S., Forleo P., Fani C., and Piacentini S. Double-blind, crossover, placebo-controlled clinical trial with l-acetylcarnitine in patients with degenerative cerebellar ataxia. Clin Neuropharmacol 23 (2000) 114-118
-
(2000)
Clin Neuropharmacol
, vol.23
, pp. 114-118
-
-
Sorbi, S.1
Forleo, P.2
Fani, C.3
Piacentini, S.4
-
166
-
-
0027933594
-
l-acetylcarnitine treatment of mental decline in the elderly
-
Salvioli G., and Neri M. l-acetylcarnitine treatment of mental decline in the elderly. Drugs Exp Clin Res 20 (1994) 169-176
-
(1994)
Drugs Exp Clin Res
, vol.20
, pp. 169-176
-
-
Salvioli, G.1
Neri, M.2
-
167
-
-
0025001584
-
Pharmaco-electroencephalographic and clinical effects of the cholinergic substance - acetyl-l-carnitine - in patients with organic brain syndrome
-
Herrmann W.M., Dietrich B., and Hiersemenzel R. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance - acetyl-l-carnitine - in patients with organic brain syndrome. Int J Clin Pharmacol Res 10 (1990) 81-84
-
(1990)
Int J Clin Pharmacol Res
, vol.10
, pp. 81-84
-
-
Herrmann, W.M.1
Dietrich, B.2
Hiersemenzel, R.3
-
168
-
-
53849128200
-
Acetyl-l-carnitine treatment in minimal hepatic encephalopathy
-
Malaguarnera M., Gargante M.P., Cristaldi E., et al. Acetyl-l-carnitine treatment in minimal hepatic encephalopathy. Dig Dis Sci 53 (2008) 3018-3025
-
(2008)
Dig Dis Sci
, vol.53
, pp. 3018-3025
-
-
Malaguarnera, M.1
Gargante, M.P.2
Cristaldi, E.3
-
169
-
-
0027182347
-
Comparison of the effects of l-carnitine, d-carnitine and acetyl-l-carnitine on the neurotoxicity of ammonia
-
Matsuoka M., and Igisu H. Comparison of the effects of l-carnitine, d-carnitine and acetyl-l-carnitine on the neurotoxicity of ammonia. Biochem Pharmacol 46 (1993) 159-164
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 159-164
-
-
Matsuoka, M.1
Igisu, H.2
-
170
-
-
67651053228
-
Branched chain amino acids supplemented with l-acetylcarnitine versus BCAA treatment in hepatic coma: a randomized and controlled double blind study
-
Malaguarnera M., Risino C., Cammalleri L., et al. Branched chain amino acids supplemented with l-acetylcarnitine versus BCAA treatment in hepatic coma: a randomized and controlled double blind study. Eur J Gastroenterol Hepatol 21 (2009) 762-770
-
(2009)
Eur J Gastroenterol Hepatol
, vol.21
, pp. 762-770
-
-
Malaguarnera, M.1
Risino, C.2
Cammalleri, L.3
-
171
-
-
59649125048
-
Comparison of pharmacokinetics of l-carnitine, acetyl-l-carnitine and propionyl-l-carnitine after single oral administration of l-carnitine in healthy volunteers
-
Cao Y., Wang Y.X., Liu C.J., Wang L.X., Han Z.W., and Wang C.B. Comparison of pharmacokinetics of l-carnitine, acetyl-l-carnitine and propionyl-l-carnitine after single oral administration of l-carnitine in healthy volunteers. Clin Invest Med 32 (2009) E13-E19
-
(2009)
Clin Invest Med
, vol.32
-
-
Cao, Y.1
Wang, Y.X.2
Liu, C.J.3
Wang, L.X.4
Han, Z.W.5
Wang, C.B.6
-
172
-
-
55949117892
-
Determination of the reference range of endogenous plasma carnitines in healthy adults
-
Reuter S.E., Evans A.M., Chace D.H., and Fornasini G. Determination of the reference range of endogenous plasma carnitines in healthy adults. Ann Clin Biochem 45 (2008) 585-592
-
(2008)
Ann Clin Biochem
, vol.45
, pp. 585-592
-
-
Reuter, S.E.1
Evans, A.M.2
Chace, D.H.3
Fornasini, G.4
-
173
-
-
37349034239
-
Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases
-
Keating D.J. Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases. J Neurochem 104 (2008) 298-305
-
(2008)
J Neurochem
, vol.104
, pp. 298-305
-
-
Keating, D.J.1
-
174
-
-
77049268148
-
Synapses in the central nervous system
-
PALAY S.L. Synapses in the central nervous system. J Biophys Biochem Cytol 2 (1956) 193-202
-
(1956)
J Biophys Biochem Cytol
, vol.2
, pp. 193-202
-
-
PALAY, S.L.1
-
175
-
-
0036591533
-
Acetyl-l-carnitine protects against amyloid-beta neurotoxicity: roles of oxidative buffering and ATP levels
-
Dhitavat S., Ortiz D., Shea T.B., and Rivera E.R. Acetyl-l-carnitine protects against amyloid-beta neurotoxicity: roles of oxidative buffering and ATP levels. Neurochem Res 27 (2002) 501-505
-
(2002)
Neurochem Res
, vol.27
, pp. 501-505
-
-
Dhitavat, S.1
Ortiz, D.2
Shea, T.B.3
Rivera, E.R.4
-
176
-
-
0037347231
-
Meta-analysis of double blind randomized controlled clinical trials of acetyl-l-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease
-
Montgomery S.A., Thal L.J., and Amrein R. Meta-analysis of double blind randomized controlled clinical trials of acetyl-l-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. Int Clin Psychopharmacol 18 (2003) 61-71
-
(2003)
Int Clin Psychopharmacol
, vol.18
, pp. 61-71
-
-
Montgomery, S.A.1
Thal, L.J.2
Amrein, R.3
-
177
-
-
0034718466
-
A 1-year controlled trial of acetyl-l-carnitine in early-onset AD
-
Thal L.J., Calvani M., Amato A., and Carta A. A 1-year controlled trial of acetyl-l-carnitine in early-onset AD. Neurology 55 (2000) 805-810
-
(2000)
Neurology
, vol.55
, pp. 805-810
-
-
Thal, L.J.1
Calvani, M.2
Amato, A.3
Carta, A.4
-
178
-
-
34547624611
-
Supply and demand in cerebral energy metabolism: the role of nutrient transporters
-
Simpson I.A., Carruthers A., and Vannucci S.J. Supply and demand in cerebral energy metabolism: the role of nutrient transporters. J Cereb Blood Flow Metab 27 (2007) 1766-1791
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1766-1791
-
-
Simpson, I.A.1
Carruthers, A.2
Vannucci, S.J.3
-
180
-
-
0018406126
-
Enhancement of mitochondrial carnitine and carnitine acylcarnitine translocase-mediated transport of fatty acids into liver mitochondria under ketogenic conditions
-
Parvin R., and Pande S.V. Enhancement of mitochondrial carnitine and carnitine acylcarnitine translocase-mediated transport of fatty acids into liver mitochondria under ketogenic conditions. J Biol Chem 254 (1979) 5423-5429
-
(1979)
J Biol Chem
, vol.254
, pp. 5423-5429
-
-
Parvin, R.1
Pande, S.V.2
-
181
-
-
0019325901
-
Relationship between acid-soluble carnitine and coenzyme a pools in vivo
-
Brass E.P., and Hoppel C.L. Relationship between acid-soluble carnitine and coenzyme a pools in vivo. Biochem J 190 (1980) 495-504
-
(1980)
Biochem J
, vol.190
, pp. 495-504
-
-
Brass, E.P.1
Hoppel, C.L.2
-
182
-
-
33748072794
-
Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis
-
Hack A., Busch V., Pascher B., et al. Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis. Pediatr Res 60 (2006) 93-96
-
(2006)
Pediatr Res
, vol.60
, pp. 93-96
-
-
Hack, A.1
Busch, V.2
Pascher, B.3
-
183
-
-
0014466113
-
Effect of carnitine on blood acetoacetate in fasting children
-
Gravina E., and Gravina-Sanvitale G. Effect of carnitine on blood acetoacetate in fasting children. Clin Chim Acta 23 (1969) 376-377
-
(1969)
Clin Chim Acta
, vol.23
, pp. 376-377
-
-
Gravina, E.1
Gravina-Sanvitale, G.2
-
184
-
-
0031566238
-
High uptake of [2-[11]]acetyl-l-carnitine into the brain: a pet study
-
Kuratsune H., Watanabe Y., Yamaguti K., et al. High uptake of [2-[11]]acetyl-l-carnitine into the brain: a pet study. Biochem Biophys Res Commun 231 (1997) 488-493
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 488-493
-
-
Kuratsune, H.1
Watanabe, Y.2
Yamaguti, K.3
-
185
-
-
33746848935
-
Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet
-
Bough K.J., Wetherington J., Hassel B., et al. Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet. Ann Neurol 60 (2006) 223-235
-
(2006)
Ann Neurol
, vol.60
, pp. 223-235
-
-
Bough, K.J.1
Wetherington, J.2
Hassel, B.3
-
187
-
-
34147189503
-
Ketogenic diet metabolites reduce firing in central neurons by opening K[ATP] channels
-
Ma W., Berg J., and Yellen G. Ketogenic diet metabolites reduce firing in central neurons by opening K[ATP] channels. J Neurosci 27 (2007) 3618-3625
-
(2007)
J Neurosci
, vol.27
, pp. 3618-3625
-
-
Ma, W.1
Berg, J.2
Yellen, G.3
-
188
-
-
21444448717
-
High-fat diet enhances visceral advanced glycation end products, nuclear O-Glc-Nac modification, p38 mitogen-activated protein kinase activation and apoptosis
-
Li S.Y., Liu Y., Sigmon V.K., McCort A., and Ren J. High-fat diet enhances visceral advanced glycation end products, nuclear O-Glc-Nac modification, p38 mitogen-activated protein kinase activation and apoptosis. Diabetes Obes Metab 7 (2005) 448-454
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 448-454
-
-
Li, S.Y.1
Liu, Y.2
Sigmon, V.K.3
McCort, A.4
Ren, J.5
|