-
2
-
-
0038363378
-
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
-
Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278: 11312-11319, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 11312-11319
-
-
Brown, A.J.1
Goldsworthy, S.M.2
Barnes, A.A.3
Eilert, M.M.4
Tcheang, L.5
Daniels, D.6
Muir, A.I.7
Wigglesworth, M.J.8
Kinghorn, I.9
Fraser, N.J.10
Pike, N.B.11
Strum, J.C.12
Steplewski, K.M.13
Murdock, P.R.14
Holder, J.C.15
Marshall, F.H.16
Szekeres, P.G.17
Wilson, S.18
Ignar, D.M.19
Foord, S.M.20
Wise, A.21
Dowell, S.J.22
more..
-
3
-
-
0037008676
-
Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE
-
Buyse M, Sitaraman SV, Liu X, Bado A, Merlin D. Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE. J Biol Chem 277: 28182-28190, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 28182-28190
-
-
Buyse, M.1
Sitaraman, S.V.2
Liu, X.3
Bado, A.4
Merlin, D.5
-
4
-
-
4143152851
-
Butyrate as an effective treatment of congenital chloride diarrhea
-
Canani RB, Terrin G, Cirillo P, Castaldo G, Salvatore F, Cardillo G, Coruzzo A, Troncone R. Butyrate as an effective treatment of congenital chloride diarrhea. Gastroenterology 127: 630-634, 2004.
-
(2004)
Gastroenterology
, vol.127
, pp. 630-634
-
-
Canani, R.B.1
Terrin, G.2
Cirillo, P.3
Castaldo, G.4
Salvatore, F.5
Cardillo, G.6
Coruzzo, A.7
Troncone, R.8
-
5
-
-
0038107464
-
Differential effects of short-chain fatty acids on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes
-
Cavaglieri CR, Nishiyama A, Fernandes LC, Curi R, Miles EA, Calder PC. Differential effects of short-chain fatty acids on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes. Life Sci 73: 1683-1690, 2003.
-
(2003)
Life Sci
, vol.73
, pp. 1683-1690
-
-
Cavaglieri, C.R.1
Nishiyama, A.2
Fernandes, L.C.3
Curi, R.4
Miles, E.A.5
Calder, P.C.6
-
6
-
-
0036432303
-
Carnitine membrane transporter deficiency: A long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency
-
Cederbaum SD, Koo-McCoy S, Tein I, Hsu BY, Ganguly A, Vilain E, Dipple K, Cvitanovic-Sojat L, Stanley C. Carnitine membrane transporter deficiency: a long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency. Mol Genet Metab 77: 195-201, 2002.
-
(2002)
Mol Genet Metab
, vol.77
, pp. 195-201
-
-
Cederbaum, S.D.1
Koo-McCoy, S.2
Tein, I.3
Hsu, B.Y.4
Ganguly, A.5
Vilain, E.6
Dipple, K.7
Cvitanovic-Sojat, L.8
Stanley, C.9
-
7
-
-
33645884705
-
Effects of L-carnitine on oxidant/antioxidant status in acetic acid-induced colitis
-
Cetinkaya A, Bulbuloglu E, Kantarceken B, Ciralik H, Kurutas EB, Buyukbese MA, Gumusalan Y. Effects of L-carnitine on oxidant/antioxidant status in acetic acid-induced colitis. Dig Dis Sci 51: 488-494, 2006.
-
(2006)
Dig Dis Sci
, vol.51
, pp. 488-494
-
-
Cetinkaya, A.1
Bulbuloglu, E.2
Kantarceken, B.3
Ciralik, H.4
Kurutas, E.B.5
Buyukbese, M.A.6
Gumusalan, Y.7
-
8
-
-
33845639988
-
Experimental colitis: Decreased Octn2 and Atb0+ expression in rat colonocytes induces carnitine depletion that is reversible by carnitineloaded liposomes
-
D'Argenio G, Calvani M, Casamassimi A, Petillo O, Margarucci S, Rienzo M, Peluso I, Calvani R, Ciccodicola A, Caporaso N, Peluso G. Experimental colitis: decreased Octn2 and Atb0+ expression in rat colonocytes induces carnitine depletion that is reversible by carnitineloaded liposomes. FASEB J 20: 2544-2546, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 2544-2546
-
-
D'Argenio, G.1
Calvani, M.2
Casamassimi, A.3
Petillo, O.4
Margarucci, S.5
Rienzo, M.6
Peluso, I.7
Calvani, R.8
Ciccodicola, A.9
Caporaso, N.10
Peluso, G.11
-
9
-
-
33845663225
-
The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation
-
Dass NB, John AK, Bassil AK, Crumbley CW, Shehee WR, Maurio FP, Moore GB, Taylor CM, Sanger GJ. The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation. Neurogastroenterol Motil 19: 66-74, 2007.
-
(2007)
Neurogastroenterol Motil
, vol.19
, pp. 66-74
-
-
Dass, N.B.1
John, A.K.2
Bassil, A.K.3
Crumbley, C.W.4
Shehee, W.R.5
Maurio, F.P.6
Moore, G.B.7
Taylor, C.M.8
Sanger, G.J.9
-
10
-
-
0036145235
-
Functional characterization of intestinal L-carnitine transport
-
Duran JM, Peral MJ, Calonge ML, Ilundain AA. Functional characterization of intestinal L-carnitine transport. J Membr Biol 185: 65-74, 2002.
-
(2002)
J Membr Biol
, vol.185
, pp. 65-74
-
-
Duran, J.M.1
Peral, M.J.2
Calonge, M.L.3
Ilundain, A.A.4
-
11
-
-
0037403719
-
Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells
-
Elimrani I, Lahjouji K, Seidman E, Roy MJ, Mitchell GA, Qureshi I. Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells. Am J Physiol Gastrointest Liver Physiol 284: G863-G871, 2003.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Elimrani, I.1
Lahjouji, K.2
Seidman, E.3
Roy, M.J.4
Mitchell, G.A.5
Qureshi, I.6
-
12
-
-
0034604611
-
Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+-and H+-coupled glutamine transporter
-
Fei YJ, Sugawara M, Nakanishi T, Huang W, Wang H, Prasad PD, Leibach FH, Ganapathy V. Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+-and H+-coupled glutamine transporter. J Biol Chem 275: 23707-23717, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 23707-23717
-
-
Fei, Y.J.1
Sugawara, M.2
Nakanishi, T.3
Huang, W.4
Wang, H.5
Prasad, P.D.6
Leibach, F.H.7
Ganapathy, V.8
-
13
-
-
33646789498
-
Relationship between CARD15, SLC22A4/5, and DLG5 polymorphisms and early-onset inflammatory bowel diseases: An Italian multicentric study
-
Ferraris A, Torres B, Knafelz D, Barabino A, Lionetti P, de Angelis GL, Iacono G, Papadatou B, D'Amato G, Di Ciommo V, Dallapiccola B, Castro M. Relationship between CARD15, SLC22A4/5, and DLG5 polymorphisms and early-onset inflammatory bowel diseases: an Italian multicentric study. Inflamm Bowel Dis 12: 355-361, 2006.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 355-361
-
-
Ferraris, A.1
Torres, B.2
Knafelz, D.3
Barabino, A.4
Lionetti, P.5
de Angelis, G.L.6
Iacono, G.7
Papadatou, B.8
D'Amato, G.9
Di Ciommo, V.10
Dallapiccola, B.11
Castro, M.12
-
14
-
-
33746935094
-
Direct or indirect association in a complex disease: The role of SLC22A4 and SLC22A5 functional variants in Crohn disease
-
Fisher SA, Hampe J, Onnie CM, Daly MJ, Curley C, Purcell S, Sanderson J, Mansfield J, Annese V, Forbes A, Lewis CM, Schreiber S, Rioux JD, Mathew CG. Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease. Hum Mutat 27: 778-785, 2006.
-
(2006)
Hum Mutat
, vol.27
, pp. 778-785
-
-
Fisher, S.A.1
Hampe, J.2
Onnie, C.M.3
Daly, M.J.4
Curley, C.5
Purcell, S.6
Sanderson, J.7
Mansfield, J.8
Annese, V.9
Forbes, A.10
Lewis, C.M.11
Schreiber, S.12
Rioux, J.D.13
Mathew, C.G.14
-
15
-
-
31544434271
-
Developmental maturation and segmental distribution of rat small intestinal L-carnitine uptake
-
Garcia-Miranda P, Duran JM, Peral MJ, Ilundain AA. Developmental maturation and segmental distribution of rat small intestinal L-carnitine uptake. J Membr Biol 206: 9-16, 2005.
-
(2005)
J Membr Biol
, vol.206
, pp. 9-16
-
-
Garcia-Miranda, P.1
Duran, J.M.2
Peral, M.J.3
Ilundain, A.A.4
-
16
-
-
0141763537
-
Effects of propionyl-L- carnitine topical irrigation in distal ulcerative colitis: A preliminary report
-
Gasbarrini G, Mingrone G, Giancaterini A, De Gaetano A, Scarfone A, Capristo E, Calvani M, Caso V, Greco AV. Effects of propionyl-L- carnitine topical irrigation in distal ulcerative colitis: a preliminary report. Hepatogastroenterology 50: 1385-1389, 2003.
-
(2003)
Hepatogastroenterology
, vol.50
, pp. 1385-1389
-
-
Gasbarrini, G.1
Mingrone, G.2
Giancaterini, A.3
De Gaetano, A.4
Scarfone, A.5
Capristo, E.6
Calvani, M.7
Caso, V.8
Greco, A.V.9
-
17
-
-
31144473386
-
Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease
-
Gazouli M, Mantzaris G, Archimandritis AJ, Nasioulas G, Anagnou NP. Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease. World J Gastroenterol 11: 7525-7530, 2005.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 7525-7530
-
-
Gazouli, M.1
Mantzaris, G.2
Archimandritis, A.J.3
Nasioulas, G.4
Anagnou, N.P.5
-
18
-
-
0034947072
-
Effects of propyonil-L-carnitine topical irrigation in distal ulcerative colitis: A preliminary report
-
Giancaterini A, Mingrone G, De Gaetano A, Capristo E, Calvani M, Caso V, Greco AV, Gasbarrini G. Effects of propyonil-L-carnitine topical irrigation in distal ulcerative colitis: a preliminary report. Am J Gastroenterol 96: 2275-2276, 2001.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 2275-2276
-
-
Giancaterini, A.1
Mingrone, G.2
De Gaetano, A.3
Capristo, E.4
Calvani, M.5
Caso, V.6
Greco, A.V.7
Gasbarrini, G.8
-
19
-
-
25444509244
-
Expression and membrane localization of MCT isoforms along the length of the human intestine
-
Gill RK, Saksena S, Alrefai WA, Sarwar Z, Goldstein JL, Carroll RE, Ramaswamy K, Dudeja PK. Expression and membrane localization of MCT isoforms along the length of the human intestine. Am J Physiol Cell Physiol 289: C846-C852, 2005.
-
(2005)
Am J Physiol Cell Physiol
, vol.289
-
-
Gill, R.K.1
Saksena, S.2
Alrefai, W.A.3
Sarwar, Z.4
Goldstein, J.L.5
Carroll, R.E.6
Ramaswamy, K.7
Dudeja, P.K.8
-
20
-
-
33847164080
-
Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract
-
Gopal E, Miyauchi S, Martin PM, Ananth S, Roon P, Smith SB, Ganapathy V. Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract. Pharm Res XX: XXX-XXX, 2007.
-
(2007)
Pharm Res
, vol.20
-
-
Gopal, E.1
Miyauchi, S.2
Martin, P.M.3
Ananth, S.4
Roon, P.5
Smith, S.B.6
Ganapathy, V.7
-
21
-
-
33645969256
-
SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter
-
Gupta N, Martin PM, Prasad PD, Ganapathy V. SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter. Life Sci 78: 2419-2425, 2006.
-
(2006)
Life Sci
, vol.78
, pp. 2419-2425
-
-
Gupta, N.1
Martin, P.M.2
Prasad, P.D.3
Ganapathy, V.4
-
22
-
-
1342329731
-
Transport of amino acid-based prodrugs by the Na+- and Cl(-)-coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery
-
Hatanaka T, Haramura M, Fei YJ, Miyauchi S, Bridges CC, Ganapathy PS, Smith SB, Ganapathy V, Ganapathy ME. Transport of amino acid-based prodrugs by the Na+- and Cl(-)-coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. J Pharmacol Exp Ther 308: 1138-1147, 2004.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 1138-1147
-
-
Hatanaka, T.1
Haramura, M.2
Fei, Y.J.3
Miyauchi, S.4
Bridges, C.C.5
Ganapathy, P.S.6
Smith, S.B.7
Ganapathy, V.8
Ganapathy, M.E.9
-
23
-
-
31644449014
-
Alterations in intestinal fatty acid metabolism in inflammatory bowel disease
-
Heimerl S, Moehle C, Zahn A, Boettcher A, Stremmel W, Langmann T, Schmitz G. Alterations in intestinal fatty acid metabolism in inflammatory bowel disease. Biochim Biophys Acta 1762: 341-350, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 341-350
-
-
Heimerl, S.1
Moehle, C.2
Zahn, A.3
Boettcher, A.4
Stremmel, W.5
Langmann, T.6
Schmitz, G.7
-
24
-
-
33646376658
-
Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine
-
Karaki S, Mitsui R, Hayashi H, Kato I, Sugiya H, Iwanaga T, Furness JB, Kuwahara A. Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res 324: 353-360, 2006.
-
(2006)
Cell Tissue Res
, vol.324
, pp. 353-360
-
-
Karaki, S.1
Mitsui, R.2
Hayashi, H.3
Kato, I.4
Sugiya, H.5
Iwanaga, T.6
Furness, J.B.7
Kuwahara, A.8
-
25
-
-
33747618018
-
Organic cation/carnitine transporter OCTN2 (Slc22a5) is responsible for carnitine transport across apical membranes of small intestinal epithelial cells in mouse
-
Kato Y, Sugiura M, Sugiura T, Wakayama T, Kubo Y, Kobayashi D, Sai Y, Tamai I, Iseki S, Tsuji A. Organic cation/carnitine transporter OCTN2 (Slc22a5) is responsible for carnitine transport across apical membranes of small intestinal epithelial cells in mouse. Mol Pharmacol 70: 829-837, 2006.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 829-837
-
-
Kato, Y.1
Sugiura, M.2
Sugiura, T.3
Wakayama, T.4
Kubo, Y.5
Kobayashi, D.6
Sai, Y.7
Tamai, I.8
Iseki, S.9
Tsuji, A.10
-
26
-
-
0036294943
-
Butyrate reduces colonic paracellular permeability by enhancing PPARgamma activation
-
Kinoshita M, Suzuki Y, Saito Y. Butyrate reduces colonic paracellular permeability by enhancing PPARgamma activation. Biochem Biophys Res Commun 293: 827-831, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 827-831
-
-
Kinoshita, M.1
Suzuki, Y.2
Saito, Y.3
-
27
-
-
0032746479
-
Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency
-
Koizumi A, Nozaki J, Ohura T, Kayo T, Wada Y, Nezu J, Ohashi R, Tamai I, Shoji Y, Takada G, Kibira S, Matsuishi T, Tsuji A. Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency. Hum Mol Genet 8: 2247-2254, 1999.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 2247-2254
-
-
Koizumi, A.1
Nozaki, J.2
Ohura, T.3
Kayo, T.4
Wada, Y.5
Nezu, J.6
Ohashi, R.7
Tamai, I.8
Shoji, Y.9
Takada, G.10
Kibira, S.11
Matsuishi, T.12
Tsuji, A.13
-
28
-
-
0038491435
-
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation
-
Le Poul E, Loison C, Struyf S, Springael JY, Lannoy V, Decobecq ME, Brezillon S, Dupriez V, Vassart G, Van Damme J, Parmentier M, Detheux M. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem 278: 25481-25489, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 25481-25489
-
-
Le Poul, E.1
Loison, C.2
Struyf, S.3
Springael, J.Y.4
Lannoy, V.5
Decobecq, M.E.6
Brezillon, S.7
Dupriez, V.8
Vassart, G.9
Van Damme, J.10
Parmentier, M.11
Detheux, M.12
-
29
-
-
33644751624
-
Polymorphisms in the organic cation transporter genes SLC22A4 and SLC22A5 and Crohn's disease in a New Zealand Caucasian cohort
-
Leung E, Hong J, Fraser AG, Merriman TR, Vishnu P, Krissansen GW. Polymorphisms in the organic cation transporter genes SLC22A4 and SLC22A5 and Crohn's disease in a New Zealand Caucasian cohort. Immunol Cell Biol 84: 233-236, 2006.
-
(2006)
Immunol Cell Biol
, vol.84
, pp. 233-236
-
-
Leung, E.1
Hong, J.2
Fraser, A.G.3
Merriman, T.R.4
Vishnu, P.5
Krissansen, G.W.6
-
30
-
-
31344451235
-
Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population
-
Martinez A, Del Carmen Martin M, Mendoza JL, Taxonera C, Diaz-Rubio M, de la Concha EG, Urcelay E. Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population. Eur J Hum Genet 14: 222-226, 2006.
-
(2006)
Eur J Hum Genet
, vol.14
, pp. 222-226
-
-
Martinez, A.1
Del Carmen Martin, M.2
Mendoza, J.L.3
Taxonera, C.4
Diaz-Rubio, M.5
de la Concha, E.G.6
Urcelay, E.7
-
31
-
-
0032523921
-
Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate
-
Matthews JB, Hassan I, Meng S, Archer SY, Hrnjez BJ, Hodin RA. Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate. J Clin Invest 101: 2072-2079, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 2072-2079
-
-
Matthews, J.B.1
Hassan, I.2
Meng, S.3
Archer, S.Y.4
Hrnjez, B.J.5
Hodin, R.A.6
-
32
-
-
4444247315
-
Cellular and physiological effects of short-chain fatty acids
-
Miller SJ. Cellular and physiological effects of short-chain fatty acids. Mini Rev Med Chem 4: 839-845, 2004.
-
(2004)
Mini Rev Med Chem
, vol.4
, pp. 839-845
-
-
Miller, S.J.1
-
33
-
-
1842778906
-
Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids
-
Miyauchi S, Gopal E, Fei YJ, Ganapathy V. Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids. J Biol Chem 279: 13293-13296, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 13293-13296
-
-
Miyauchi, S.1
Gopal, E.2
Fei, Y.J.3
Ganapathy, V.4
-
34
-
-
0035870096
-
Na+- and Cl-coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes
-
Nakanishi T, Hatanaka T, Huang W, Prasad PD, Leibach FH, Ganapathy ME, Ganapathy V. Na+- and Cl-coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes. J Physiol 532: 297-304, 2001.
-
(2001)
J Physiol
, vol.532
, pp. 297-304
-
-
Nakanishi, T.1
Hatanaka, T.2
Huang, W.3
Prasad, P.D.4
Leibach, F.H.5
Ganapathy, M.E.6
Ganapathy, V.7
-
35
-
-
14944356373
-
A risk haplotype in the solute carrier family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease
-
Newman B, Gu X, Wintle R, Cescon D, Yazdanpanah M, Liu X, Peltekova V, Van Oene M, Amos CI, Siminovitch KA. A risk haplotype in the solute carrier family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease. Gastroenterology 128: 260-269, 2005.
-
(2005)
Gastroenterology
, vol.128
, pp. 260-269
-
-
Newman, B.1
Gu, X.2
Wintle, R.3
Cescon, D.4
Yazdanpanah, M.5
Liu, X.6
Peltekova, V.7
Van Oene, M.8
Amos, C.I.9
Siminovitch, K.A.10
-
36
-
-
28844509940
-
The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease
-
Noble CL, Nimmo ER, Drummond H, Ho GT, Tenesa A, Smith L, Anderson N, Arnott ID, Satsangi J. The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease. Gastroenterology 129: 1854-1864, 2005.
-
(2005)
Gastroenterology
, vol.129
, pp. 1854-1864
-
-
Noble, C.L.1
Nimmo, E.R.2
Drummond, H.3
Ho, G.T.4
Tenesa, A.5
Smith, L.6
Anderson, N.7
Arnott, I.D.8
Satsangi, J.9
-
37
-
-
33644924311
-
Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis
-
Palmieri O, Latiano A, Valvano R, D'Inca R, Vecchi M, Sturniolo GC, Saibeni S, Peyvandi F, Bossa F, Zagaria C, Andriulli A, Devoto M, Annese V. Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther 23: 497-506, 2006.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 497-506
-
-
Palmieri, O.1
Latiano, A.2
Valvano, R.3
D'Inca, R.4
Vecchi, M.5
Sturniolo, G.C.6
Saibeni, S.7
Peyvandi, F.8
Bossa, F.9
Zagaria, C.10
Andriulli, A.11
Devoto, M.12
Annese, V.13
-
38
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova VD, Wintle RF, Rubin LA, Amos CI, Huang Q, Gu X, Newman B, Van Oene M, Cescon D, Greenberg G, Griffiths AM, St. George-Hyslop PH, Siminovitch KA. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat Genet 36: 471-475, 2004.
-
(2004)
Nat Genet
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
Wintle, R.F.2
Rubin, L.A.3
Amos, C.I.4
Huang, Q.5
Gu, X.6
Newman, B.7
Van Oene, M.8
Cescon, D.9
Greenberg, G.10
Griffiths, A.M.11
St. George-Hyslop, P.H.12
Siminovitch, K.A.13
-
39
-
-
0025366260
-
The effects of enterotoxins and short-chain fatty acids on water and electrolyte fluxes in ileal and colonic loops in vivo in the rat
-
Ramakrishna BS, Nance SH, Roberts-Thomson IC, Roediger WE. The effects of enterotoxins and short-chain fatty acids on water and electrolyte fluxes in ileal and colonic loops in vivo in the rat. Digestion 45: 93-101, 1990.
-
(1990)
Digestion
, vol.45
, pp. 93-101
-
-
Ramakrishna, B.S.1
Nance, S.H.2
Roberts-Thomson, I.C.3
Roediger, W.E.4
-
40
-
-
0035203147
-
Fatty acid transport and mitochondrial oxidation disorders
-
Rinaldo P. Fatty acid transport and mitochondrial oxidation disorders. Semin Liver Dis 21: 489-500, 2001.
-
(2001)
Semin Liver Dis
, vol.21
, pp. 489-500
-
-
Rinaldo, P.1
-
42
-
-
0031751184
-
Clinical and biochemical features of fatty acid oxidation disorders
-
Rinaldo P, Raymond K, al-Odaib A, Bennett MJ. Clinical and biochemical features of fatty acid oxidation disorders. Curr Opin Pediatr 10: 615-621, 1998.
-
(1998)
Curr Opin Pediatr
, vol.10
, pp. 615-621
-
-
Rinaldo, P.1
Raymond, K.2
al-Odaib, A.3
Bennett, M.J.4
-
43
-
-
0023013994
-
Metabolic induction of experimental ulcerative colitis by inhibition of fatty acid oxidation
-
Roediger WE, Nance S. Metabolic induction of experimental ulcerative colitis by inhibition of fatty acid oxidation. Br J Exp Pathol 67: 773-782, 1986.
-
(1986)
Br J Exp Pathol
, vol.67
, pp. 773-782
-
-
Roediger, W.E.1
Nance, S.2
-
44
-
-
0025012338
-
Selective reduction of fatty acid oxidation in colonocytes: Correlation with ulcerative colitis
-
Roediger WE, Nance S. Selective reduction of fatty acid oxidation in colonocytes: correlation with ulcerative colitis. Lipids 25: 646-652, 1990.
-
(1990)
Lipids
, vol.25
, pp. 646-652
-
-
Roediger, W.E.1
Nance, S.2
-
45
-
-
33646061100
-
Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease
-
Russell RK, Drummond HE, Nimmo ER, Anderson NH, Noble CL, Wilson DC, Gillett PM, McGrogan P, Hassan K, Weaver LT, Bisset WM, Mahdi G, Satsangi J. Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease. Gut 55: 1114-1123, 2006.
-
(2006)
Gut
, vol.55
, pp. 1114-1123
-
-
Russell, R.K.1
Drummond, H.E.2
Nimmo, E.R.3
Anderson, N.H.4
Noble, C.L.5
Wilson, D.C.6
Gillett, P.M.7
McGrogan, P.8
Hassan, K.9
Weaver, L.T.10
Bisset, W.M.11
Mahdi, G.12
Satsangi, J.13
-
47
-
-
0003720078
-
-
New York: McGraw Hill
-
Scriver CR, Beaudet AL, Sly WS, Valle D, Childs B. The Metabolic and Molecular basis of Inherited Diseases. New York: McGraw Hill, 2001.
-
(2001)
The Metabolic and Molecular basis of Inherited Diseases
-
-
Scriver, C.R.1
Beaudet, A.L.2
Sly, W.S.3
Valle, D.4
Childs, B.5
-
48
-
-
0033585084
-
Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function
-
Seth P, Wu X, Huang W, Leibach FH, Ganapathy V. Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function. J Biol Chem 274: 33388-33392, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 33388-33392
-
-
Seth, P.1
Wu, X.2
Huang, W.3
Leibach, F.H.4
Ganapathy, V.5
-
49
-
-
0038177998
-
Human placenta metabolizes fatty acids: Implications for fetal fatty acid oxidation disorders and maternal liver diseases
-
Shekhawat P, Bennett MJ, Sadovsky Y, Nelson DM, Rakheja D, Strauss AW. Human placenta metabolizes fatty acids: implications for fetal fatty acid oxidation disorders and maternal liver diseases. Am J Physiol Endocrinol Metab 284: E1098-E1105, 2003.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
-
-
Shekhawat, P.1
Bennett, M.J.2
Sadovsky, Y.3
Nelson, D.M.4
Rakheja, D.5
Strauss, A.W.6
-
50
-
-
36248946755
-
-/--) mice
-
In Press
-
-/--) mice. Mol Genet Metab. In Press.
-
Mol Genet Metab
-
-
Shekhawat, P.S.1
Srinivas, S.R.2
Matern, D.3
Bennett, M.J.4
Boriack, R.5
George, V.6
Xu, H.7
Prasad, P.D.8
Roon, P.9
Ganapathy, V.10
-
51
-
-
0142151107
-
Silent and symptomatic primary carnitine deficiency within the same family due to identical mutations in the organic cation/carnitine transporter OCTN2
-
Spiekerkoetter U, Huener G, Baykal T, Demirkol M, Duran M, Wanders R, Nezu J, Mayatepek E. Silent and symptomatic primary carnitine deficiency within the same family due to identical mutations in the organic cation/carnitine transporter OCTN2. J Inherit Metab Dis 26: 613-615, 2003.
-
(2003)
J Inherit Metab Dis
, vol.26
, pp. 613-615
-
-
Spiekerkoetter, U.1
Huener, G.2
Baykal, T.3
Demirkol, M.4
Duran, M.5
Wanders, R.6
Nezu, J.7
Mayatepek, E.8
-
52
-
-
33847021854
-
Neutral Na-amino acid cotransport is differentially regulated by glucocorticoids in the normal and chronically inflamed rabbit small intestine
-
Sundaram U, Wisel S, Coon S. Neutral Na-amino acid cotransport is differentially regulated by glucocorticoids in the normal and chronically inflamed rabbit small intestine. Am J Physiol Gastrointest Liver Physiol 292: G467-G474, 2007.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
-
-
Sundaram, U.1
Wisel, S.2
Coon, S.3
-
53
-
-
1842531133
-
Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition
-
Tong X, Yin L, Giardina C. Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition. Biochem Biophys Res Commun 317: 463-471, 2004.
-
(2004)
Biochem Biophys Res Commun
, vol.317
, pp. 463-471
-
-
Tong, X.1
Yin, L.2
Giardina, C.3
-
54
-
-
33846949327
-
Contribution of the IBD5 locus to Crohn's disease in the Swedish population
-
Torkvist L, Noble CL, Lordal M, Sjoqvist U, Lindforss U, Nimmo ER, Lofberg R, Russell RK, Satsangi J. Contribution of the IBD5 locus to Crohn's disease in the Swedish population. Scand J Gastroenterol 42: 200-206, 2007.
-
(2007)
Scand J Gastroenterol
, vol.42
, pp. 200-206
-
-
Torkvist, L.1
Noble, C.L.2
Lordal, M.3
Sjoqvist, U.4
Lindforss, U.5
Nimmo, E.R.6
Lofberg, R.7
Russell, R.K.8
Satsangi, J.9
-
55
-
-
21344449654
-
Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease
-
Torok HP, Glas J, Tonenchi L, Lohse P, Muller-Myhsok B, Limbersky O, Neugebauer C, Schnitzler F, Seiderer J, Tillack C, Brand S, Brunnler G, Jagiello P, Epplen JT, Griga T, Klein W, Schiemann U, Folwaczny M, Ochsenkuhn T, Folwaczny C. Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. Gut 54: 1421-1427, 2005.
-
(2005)
Gut
, vol.54
, pp. 1421-1427
-
-
Torok, H.P.1
Glas, J.2
Tonenchi, L.3
Lohse, P.4
Muller-Myhsok, B.5
Limbersky, O.6
Neugebauer, C.7
Schnitzler, F.8
Seiderer, J.9
Tillack, C.10
Brand, S.11
Brunnler, G.12
Jagiello, P.13
Epplen, J.T.14
Griga, T.15
Klein, W.16
Schiemann, U.17
Folwaczny, M.18
Ochsenkuhn, T.19
Folwaczny, C.20
more..
-
56
-
-
28844459843
-
Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD
-
Vermeire S, Pierik M, Hlavaty T, Claessens G, van Schuerbeeck N, Joossens S, Ferrante M, Henckaerts L, Bueno de Mesquita M, Vlietinck R, Rutgeerts P. Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD. Gastroenterology 129: 1845-1853, 2005.
-
(2005)
Gastroenterology
, vol.129
, pp. 1845-1853
-
-
Vermeire, S.1
Pierik, M.2
Hlavaty, T.3
Claessens, G.4
van Schuerbeeck, N.5
Joossens, S.6
Ferrante, M.7
Henckaerts, L.8
Bueno de Mesquita, M.9
Vlietinck, R.10
Rutgeerts, P.11
-
57
-
-
28544444993
-
Current status of genetics research in inflammatory bowel disease
-
Vermeire S, Rutgeerts P. Current status of genetics research in inflammatory bowel disease. Genes Immun 6: 637-645, 2005.
-
(2005)
Genes Immun
, vol.6
, pp. 637-645
-
-
Vermeire, S.1
Rutgeerts, P.2
-
58
-
-
0033834091
-
+-carnitine cotransporter hOCTN2
-
+-carnitine cotransporter hOCTN2. Am J Physiol Renal Physiol 279: F584-F591, 2000.
-
(2000)
Am J Physiol Renal Physiol
, vol.279
-
-
Wagner, C.A.1
Lukewille, U.2
Kaltenbach, S.3
Moschen, I.4
Broer, A.5
Risler, T.6
Broer, S.7
Lang, F.8
-
59
-
-
33646779514
-
Evidence for association of OCTN genes and IBD5 with ulcerative colitis
-
Waller S, Tremelling M, Bredin F, Godfrey L, Howson J, Parkes M. Evidence for association of OCTN genes and IBD5 with ulcerative colitis. Gut 55: 809-814, 2006.
-
(2006)
Gut
, vol.55
, pp. 809-814
-
-
Waller, S.1
Tremelling, M.2
Bredin, F.3
Godfrey, L.4
Howson, J.5
Parkes, M.6
-
60
-
-
0034049311
-
A missense mutation in the OCTN2 gene associated with residual carnitine transport activity
-
Wang Y, Kelly MA, Cowan TM, Longo N. A missense mutation in the OCTN2 gene associated with residual carnitine transport activity. Hum Mutat 15: 238-245, 2000.
-
(2000)
Hum Mutat
, vol.15
, pp. 238-245
-
-
Wang, Y.1
Kelly, M.A.2
Cowan, T.M.3
Longo, N.4
-
61
-
-
0033515017
-
Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency
-
Wang Y, Ye J, Ganapathy V, Longo N. Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency. Proc Natl Acad Sci USA 96: 2356-2360, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2356-2360
-
-
Wang, Y.1
Ye, J.2
Ganapathy, V.3
Longo, N.4
-
62
-
-
0035052047
-
Carnitine transporter defect diagnosed by newborn screening with electrospray tandem mass spectrometry
-
Wilcken B, Wiley V, Sim KG, Carpenter K. Carnitine transporter defect diagnosed by newborn screening with electrospray tandem mass spectrometry. J Pediatr 138: 581-584, 2001.
-
(2001)
J Pediatr
, vol.138
, pp. 581-584
-
-
Wilcken, B.1
Wiley, V.2
Sim, K.G.3
Carpenter, K.4
-
63
-
-
0032767691
-
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter
-
Wu X, Huang W, Prasad PD, Seth P, Rajan DP, Leibach FH, Chen J, Conway SJ, Ganapathy V. Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. J Pharmacol Exp Ther 290: 1482-1492, 1999.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 1482-1492
-
-
Wu, X.1
Huang, W.2
Prasad, P.D.3
Seth, P.4
Rajan, D.P.5
Leibach, F.H.6
Chen, J.7
Conway, S.J.8
Ganapathy, V.9
-
64
-
-
0032577202
-
cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family
-
Wu X, Prasad PD, Leibach FH, Ganapathy V. cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family. Biochem Biophys Res Commun 246: 589-595, 1998.
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 589-595
-
-
Wu, X.1
Prasad, P.D.2
Leibach, F.H.3
Ganapathy, V.4
-
65
-
-
0742305675
-
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
-
Xiong Y, Miyamoto N, Shibata K, Valasek MA, Motoike T, Kedzierski RM, Yanagisawa M. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci USA 101: 1045-1050, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1045-1050
-
-
Xiong, Y.1
Miyamoto, N.2
Shibata, K.3
Valasek, M.A.4
Motoike, T.5
Kedzierski, R.M.6
Yanagisawa, M.7
-
66
-
-
12744274602
-
Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease
-
Yamazaki K, Takazoe M, Tanaka T, Ichimori T, Saito S, Iida A, Onouchi Y, Hata A, Nakamura Y. Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease. J Hum Genet 49: 664-668, 2004.
-
(2004)
J Hum Genet
, vol.49
, pp. 664-668
-
-
Yamazaki, K.1
Takazoe, M.2
Tanaka, T.3
Ichimori, T.4
Saito, S.5
Iida, A.6
Onouchi, Y.7
Hata, A.8
Nakamura, Y.9
-
67
-
-
0032952772
-
Decreased tissue distribution of L-carnitine in juvenile visceral steatosis mice
-
Yokogawa K, Higashi Y, Tamai I, Nomura M, Hashimoto N, Nikaido H, Hayakawa J, Miyamoto K, Tsuji A. Decreased tissue distribution of L-carnitine in juvenile visceral steatosis mice. J Pharmacol Exp Ther 289: 224-230, 1999.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 224-230
-
-
Yokogawa, K.1
Higashi, Y.2
Tamai, I.3
Nomura, M.4
Hashimoto, N.5
Nikaido, H.6
Hayakawa, J.7
Miyamoto, K.8
Tsuji, A.9
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