Abnormal mitochondrial dynamics-a novel therapeutic target for alzheimer's disease?

Molecular Neurobiology

Volumn 41, Issue 2-3, 2010, Pages 87-96

  Su, Bo ^a   Wang, Xinglong ^a   Bonda, David ^a   Perry, Gorge ^a,b   Smith, Mark ^a   Zhu, Xiongwei ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b University of San Antonio   (United States)

Author keywords

Alzheimer's disease; Dimebon; Drug; Mitochondrial dynamics; Mitochondrial fission; Mitochondrial fusion

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; ANTIOXIDANT; APOLIPOPROTEIN E4; ASCORBIC ACID; CISPLATIN; DIMEBON; DONEPEZIL; DYNAMIN; DYNAMIN LIKE PROTEIN 1; GLUTATHIONE; GUANOSINE TRIPHOSPHATASE; LEVACECARNINE; NOOTROPIC AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PLACEBO; PRESENILIN; PROTEIN INHIBITOR; PROTEIN MDIVI 1; TAU PROTEIN; THIOCTIC ACID; UBIDECARENONE; UNCLASSIFIED DRUG; INDOLE DERIVATIVE;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; APOPTOSIS; BRAIN MITOCHONDRION; CELL FUNCTION; CELL SURVIVAL; CLINICAL TRIAL; CONFERENCE PAPER; DIET SUPPLEMENTATION; DISEASE COURSE; DRUG EFFICACY; DRUG TARGETING; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; META ANALYSIS; MOLECULAR DYNAMICS; NERVE CELL; NEUROFIBRILLARY TANGLE; NEUROPROTECTION; NITROSYLATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SYSTEMATIC REVIEW; UNSPECIFIED SIDE EFFECT; ANIMAL; CLINICAL TRIAL (TOPIC); CYTOLOGY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY;

ALZHEIMER DISEASE; ANIMALS; ANTIOXIDANTS; APOLIPOPROTEIN E4; CLINICAL TRIALS AS TOPIC; HUMANS; INDOLES; MITOCHONDRIA; NEURONS; PRESENILINS; TAU PROTEINS;

EID: 77955090213     PISSN: 08937648     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12035-009-8095-7     Document Type: Conference Paper

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