메뉴 건너뛰기




Volumn 22, Issue 3, 2015, Pages 398-407

Autophagy in the physiology and pathology of the central nervous system

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ASTROCYTE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL EXPANSION; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; DEVELOPMENTAL DISORDER; ENDOSOME; ENVIRONMENTAL STRESS; GOLGI COMPLEX; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIPOPHAGOCYTOSIS; LONG TERM DEPRESSION; LONG TERM POTENTIATION; LYSOSOME; LYSOSOME STORAGE DISEASE; MACROAUTOPHAGY; MICROTUBULE; MITOCHONDRION; MITOPHAGY; NECROSIS; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROLOGIC DISEASE; NIEMANN PICK DISEASE; NONHUMAN; NUCLEOPHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; RETINITIS PIGMENTOSA; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; PATHOLOGY; PHYSIOLOGY;

EID: 84922507788     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.204     Document Type: Review
Times cited : (166)

References (109)
  • 1
    • 84880376355 scopus 로고    scopus 로고
    • Emerging regulation and functions of autophagy
    • Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol 2013; 15: 713-720.
    • (2013) Nat Cell Biol , vol.15 , pp. 713-720
    • Boya, P.1    Reggiori, F.2    Codogno, P.3
  • 2
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011; 147: 728-741.
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 3
    • 77956178939 scopus 로고    scopus 로고
    • Chaperone-mediated autophagy: Molecular mechanisms and physiological relevance
    • Orenstein SJ, Cuervo AM. Chaperone-mediated autophagy: molecular mechanisms and physiological relevance. Semin Cell Dev Biol 2010; 21: 719-726.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 719-726
    • Orenstein, S.J.1    Cuervo, A.M.2
  • 4
    • 84866155363 scopus 로고    scopus 로고
    • Neuronal autophagy: A housekeeper or a fighter in neuronal cell survival?
    • Lee JA. Neuronal autophagy: a housekeeper or a fighter in neuronal cell survival? Exp Neurobiol 2012; 21: 1-8.
    • (2012) Exp Neurobiol , vol.21 , pp. 1-8
    • Lee, J.A.1
  • 5
    • 79955631150 scopus 로고    scopus 로고
    • Autophagy in the cellular energetic balance
    • Singh R, Cuervo AM. Autophagy in the cellular energetic balance. Cell Metab 2011; 13: 495-504.
    • (2011) Cell Metab , vol.13 , pp. 495-504
    • Singh, R.1    Cuervo, A.M.2
  • 6
    • 0042322394 scopus 로고    scopus 로고
    • Autophagy in yeast: A TOR-mediated response to nutrient starvation
    • Kamada Y, Sekito T, Ohsumi Y. Autophagy in yeast: a TOR-mediated response to nutrient starvation. Curr Top Microbiol Immunol 2004; 279: 73-84.
    • (2004) Curr Top Microbiol Immunol , vol.279 , pp. 73-84
    • Kamada, Y.1    Sekito, T.2    Ohsumi, Y.3
  • 7
    • 77951227871 scopus 로고    scopus 로고
    • TOR-dependent control of autophagy: Biting the hand that feeds
    • Neufeld TP. TOR-dependent control of autophagy: biting the hand that feeds. Curr Opin Cell Biol 2010; 22: 157-168.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 157-168
    • Neufeld, T.P.1
  • 8
    • 84884634690 scopus 로고    scopus 로고
    • Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: Autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
    • Sarkar S. Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers. Biochem Soc Trans 2013; 41: 1103-1130.
    • (2013) Biochem Soc Trans , vol.41 , pp. 1103-1130
    • Sarkar, S.1
  • 9
    • 65249119430 scopus 로고    scopus 로고
    • Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
    • Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell 2009; 20: 1981-1991.
    • (2009) Mol Biol Cell , vol.20 , pp. 1981-1991
    • Hosokawa, N.1    Hara, T.2    Kaizuka, T.3    Kishi, C.4    Takamura, A.5    Miura, Y.6
  • 10
    • 50249084987 scopus 로고    scopus 로고
    • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
    • Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182: 685-701.
    • (2008) J Cell Biol , vol.182 , pp. 685-701
    • Axe, E.L.1    Walker, S.A.2    Manifava, M.3    Chandra, P.4    Roderick, H.L.5    Habermann, A.6
  • 11
    • 77954184503 scopus 로고    scopus 로고
    • Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae
    • Geng J, Nair U, Yasumura-Yorimitsu K, Klionsky DJ. Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae. Mol Biol Cell 2010; 21: 2257-2269.
    • (2010) Mol Biol Cell , vol.21 , pp. 2257-2269
    • Geng, J.1    Nair, U.2    Yasumura-Yorimitsu, K.3    Klionsky, D.J.4
  • 13
    • 78649281871 scopus 로고    scopus 로고
    • Plasma membrane helps autophagosomes grow
    • Ravikumar B, Moreau K, Rubinsztein DC. Plasma membrane helps autophagosomes grow. Autophagy 2010; 6: 1184-1186.
    • (2010) Autophagy , vol.6 , pp. 1184-1186
    • Ravikumar, B.1    Moreau, K.2    Rubinsztein, D.C.3
  • 14
    • 8044257699 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
    • Blommaart EF, Krause U, Schellens JP, Vreeling-Sindelarova H, Meijer AJ. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur J Biochem 1997; 243 (1-2): 240-246.
    • (1997) Eur J Biochem , vol.243 , Issue.1-2 , pp. 240-246
    • Blommaart, E.F.1    Krause, U.2    Schellens, J.P.3    Vreeling-Sindelarova, H.4    Meijer, A.J.5
  • 16
    • 0035809160 scopus 로고    scopus 로고
    • Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
    • Kihara A, Noda T, Ishihara N, Ohsumi Y. Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 2001; 152: 519-530.
    • (2001) J Cell Biol , vol.152 , pp. 519-530
    • Kihara, A.1    Noda, T.2    Ishihara, N.3    Ohsumi, Y.4
  • 17
    • 50249089984 scopus 로고    scopus 로고
    • Beyond autophagy: The role of UVRAG in membrane trafficking
    • Liang C, Sir D, Lee S, Ou JH, Jung JU. Beyond autophagy: the role of UVRAG in membrane trafficking. Autophagy 2008; 4: 817-820.
    • (2008) Autophagy , vol.4 , pp. 817-820
    • Liang, C.1    Sir, D.2    Lee, S.3    Ou, J.H.4    Jung, J.U.5
  • 18
    • 66449083078 scopus 로고    scopus 로고
    • ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
    • Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 2009; 284: 12297-12305.
    • (2009) J Biol Chem , vol.284 , pp. 12297-12305
    • Ganley, I.G.1    Lam Du, H.2    Wang, J.3    Ding, X.4    Chen, S.5    Jiang, X.6
  • 19
    • 0038325675 scopus 로고    scopus 로고
    • Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
    • Mizushima N, Kuma A, Kobayashi Y, Yamamoto A, Matsubae M, Takao T et al. Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci 2003; 116(Pt 9): 1679-1688.
    • (2003) J Cell Sci , vol.116 , pp. 1679-1688
    • Mizushima, N.1    Kuma, A.2    Kobayashi, Y.3    Yamamoto, A.4    Matsubae, M.5    Takao, T.6
  • 20
    • 0033565655 scopus 로고    scopus 로고
    • Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway
    • Mizushima N, Noda T, Ohsumi Y. Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J 1999; 18: 3888-3896.
    • (1999) EMBO J , vol.18 , pp. 3888-3896
    • Mizushima, N.1    Noda, T.2    Ohsumi, Y.3
  • 22
    • 0035910423 scopus 로고    scopus 로고
    • The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
    • Tanida I, Tanida-Miyake E, Ueno T, Kominami E. The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J Biol Chem 2001; 276: 1701-1706.
    • (2001) J Biol Chem , vol.276 , pp. 1701-1706
    • Tanida, I.1    Tanida-Miyake, E.2    Ueno, T.3    Kominami, E.4
  • 24
    • 34447099450 scopus 로고    scopus 로고
    • Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion
    • Nakatogawa H, Ichimura Y, Ohsumi Y. Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. Cell 2007; 130: 165-178.
    • (2007) Cell , vol.130 , pp. 165-178
    • Nakatogawa, H.1    Ichimura, Y.2    Ohsumi, Y.3
  • 25
    • 79954544250 scopus 로고    scopus 로고
    • LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis
    • Weidberg H, Shpilka T, Shvets E, Abada A, Shimron F, Elazar Z. LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis. Dev Cell 2011; 20: 444-454.
    • (2011) Dev Cell , vol.20 , pp. 444-454
    • Weidberg, H.1    Shpilka, T.2    Shvets, E.3    Abada, A.4    Shimron, F.5    Elazar, Z.6
  • 27
    • 0024299286 scopus 로고
    • Prelysosomal convergence of autophagic and endocytic pathways
    • Gordon PB, Seglen PO. Prelysosomal convergence of autophagic and endocytic pathways. Biochem Biophys Res Commun 1988; 151: 40-47.
    • (1988) Biochem Biophys Res Commun , vol.151 , pp. 40-47
    • Gordon, P.B.1    Seglen, P.O.2
  • 28
    • 0032532323 scopus 로고    scopus 로고
    • Purification and characterization of autophagosomes from rat hepatocytes
    • Stromhaug PE, Berg TO, Fengsrud M, Seglen PO. Purification and characterization of autophagosomes from rat hepatocytes. Biochem J 1998; 335(Pt 2): 217-224.
    • (1998) Biochem J , vol.335 , pp. 217-224
    • Stromhaug, P.E.1    Berg, T.O.2    Fengsrud, M.3    Seglen, P.O.4
  • 30
    • 26844531363 scopus 로고    scopus 로고
    • Maturation of autophagic vacuoles in mammalian cells
    • Eskelinen EL. Maturation of autophagic vacuoles in mammalian cells. Autophagy 2005; 1: 1-10.
    • (2005) Autophagy , vol.1 , pp. 1-10
    • Eskelinen, E.L.1
  • 31
    • 77953792923 scopus 로고    scopus 로고
    • Mediatory molecules that fuse autophagosomes and lysosomes
    • Furuta N, Yoshimori T, Amano A. Mediatory molecules that fuse autophagosomes and lysosomes. Autophagy 2010; 6: 417-418.
    • (2010) Autophagy , vol.6 , pp. 417-418
    • Furuta, N.1    Yoshimori, T.2    Amano, A.3
  • 32
    • 34548492271 scopus 로고    scopus 로고
    • ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
    • Lee JA, Beigneux A, Ahmad ST, Young SG, Gao FB. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr Biol 2007; 17: 1561-1567.
    • (2007) Curr Biol , vol.17 , pp. 1561-1567
    • Lee, J.A.1    Beigneux, A.2    Ahmad, S.T.3    Young, S.G.4    Gao, F.B.5
  • 33
    • 79551546749 scopus 로고    scopus 로고
    • Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex
    • Renna M, Schaffner C, Winslow AR, Menzies FM, Peden AA, Floto RA et al. Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex. J Cell Sci 2011; 124 (Pt 3): 469-482.
    • (2011) J Cell Sci , vol.124 , pp. 469-482
    • Renna, M.1    Schaffner, C.2    Winslow, A.R.3    Menzies, F.M.4    Peden, A.A.5    Floto, R.A.6
  • 34
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004; 15: 1101-1111.
    • (2004) Mol Biol Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 35
    • 0034304390 scopus 로고    scopus 로고
    • The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: A review
    • Nixon RA, Cataldo AM, Mathews PM. The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review. Neurochem Res 2000; 25: 1161-1172.
    • (2000) Neurochem Res , vol.25 , pp. 1161-1172
    • Nixon, R.A.1    Cataldo, A.M.2    Mathews, P.M.3
  • 36
    • 49049096562 scopus 로고    scopus 로고
    • Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
    • Boland B, Kumar A, Lee S, Platt FM, Wegiel J, Yu WH et al. Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J Neurosci 2008; 28: 6926-6937.
    • (2008) J Neurosci , vol.28 , pp. 6926-6937
    • Boland, B.1    Kumar, A.2    Lee, S.3    Platt, F.M.4    Wegiel, J.5    Yu, W.H.6
  • 37
    • 82855181986 scopus 로고    scopus 로고
    • Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy
    • Lee S, Sato Y, Nixon RA. Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy. Autophagy 2011; 7: 1562-1563.
    • (2011) Autophagy , vol.7 , pp. 1562-1563
    • Lee, S.1    Sato, Y.2    Nixon, R.A.3
  • 38
    • 84904266112 scopus 로고    scopus 로고
    • Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway
    • Maday S, Holzbaur EL. Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway. Dev Cell 2014; 30: 71-85.
    • (2014) Dev Cell , vol.30 , pp. 71-85
    • Maday, S.1    Holzbaur, E.L.2
  • 39
    • 33745192802 scopus 로고    scopus 로고
    • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
    • Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441: 885-889.
    • (2006) Nature , vol.441 , pp. 885-889
    • Hara, T.1    Nakamura, K.2    Matsui, M.3    Yamamoto, A.4    Nakahara, Y.5    Suzuki-Migishima, R.6
  • 40
    • 33646800306 scopus 로고    scopus 로고
    • Loss of autophagy in the central nervous system causes neurodegeneration in mice
    • Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441: 880-884.
    • (2006) Nature , vol.441 , pp. 880-884
    • Komatsu, M.1    Waguri, S.2    Chiba, T.3    Murata, S.4    Iwata, J.5    Tanida, I.6
  • 41
    • 21044455137 scopus 로고    scopus 로고
    • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
    • Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005; 169: 425-434.
    • (2005) J Cell Biol , vol.169 , pp. 425-434
    • Komatsu, M.1    Waguri, S.2    Ueno, T.3    Iwata, J.4    Murata, S.5    Tanida, I.6
  • 42
    • 84878811164 scopus 로고    scopus 로고
    • Mitochondria and quality control defects in a mouse model of Gaucher disease-links to Parkinson's disease
    • Osellame LD, Rahim AA, Hargreaves IP, Gegg ME, Richard-Londt A, Brandner S et al. Mitochondria and quality control defects in a mouse model of Gaucher disease-links to Parkinson's disease. Cell Metab 2013; 17: 941-953.
    • (2013) Cell Metab , vol.17 , pp. 941-953
    • Osellame, L.D.1    Rahim, A.A.2    Hargreaves, I.P.3    Gegg, M.E.4    Richard-Londt, A.5    Brandner, S.6
  • 43
    • 84865531819 scopus 로고    scopus 로고
    • Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder
    • Di Malta C, Fryer JD, Settembre C, Ballabio A. Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder. Proc Natl Acad Sci U S A 2012; 109: E2334-E2342.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E2334-E2342
    • Di Malta, C.1    Fryer, J.D.2    Settembre, C.3    Ballabio, A.4
  • 44
    • 77954064073 scopus 로고    scopus 로고
    • Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition
    • Calkins MJ, Vargas MR, Johnson DA, Johnson JA. Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition. Toxicol Sci 2010; 115: 557-568.
    • (2010) Toxicol Sci , vol.115 , pp. 557-568
    • Calkins, M.J.1    Vargas, M.R.2    Johnson, D.A.3    Johnson, J.A.4
  • 45
    • 62449132771 scopus 로고    scopus 로고
    • Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
    • Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, Kan YW et al. Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: critical role for the astrocyte. Proc Natl Acad Sci USA 2009; 106: 2933-2938.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2933-2938
    • Chen, P.C.1    Vargas, M.R.2    Pani, A.K.3    Smeyne, R.J.4    Johnson, D.A.5    Kan, Y.W.6
  • 46
    • 58149379610 scopus 로고    scopus 로고
    • Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis
    • Vargas MR, Johnson DA, Sirkis DW, Messing A, Johnson JA. Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J Neurosci 2008; 28: 13574-13581.
    • (2008) J Neurosci , vol.28 , pp. 13574-13581
    • Vargas, M.R.1    Johnson, D.A.2    Sirkis, D.W.3    Messing, A.4    Johnson, J.A.5
  • 47
    • 84870549095 scopus 로고    scopus 로고
    • Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model
    • Gan L, Vargas MR, Johnson DA, Johnson JA. Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model. J Neurosci 2012; 32: 17775-17787.
    • (2012) J Neurosci , vol.32 , pp. 17775-17787
    • Gan, L.1    Vargas, M.R.2    Johnson, D.A.3    Johnson, J.A.4
  • 48
    • 84889650334 scopus 로고    scopus 로고
    • Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance
    • Motori E, Puyal J, Toni N, Ghanem A, Angeloni C, Malaguti M et al. Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance. Cell Metab 2013; 18: 844-859.
    • (2013) Cell Metab , vol.18 , pp. 844-859
    • Motori, E.1    Puyal, J.2    Toni, N.3    Ghanem, A.4    Angeloni, C.5    Malaguti, M.6
  • 50
    • 35448938087 scopus 로고    scopus 로고
    • Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
    • Komatsu M, Wang QJ, Holstein GR, Friedrich Jr VL, Iwata J, Kominami E et al. Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc Natl Acad Sci USA 2007; 104: 14489-14494.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14489-14494
    • Komatsu, M.1    Wang, Q.J.2    Holstein, G.R.3    Friedrich, V.L.4    Iwata, J.5    Kominami, E.6
  • 51
    • 61949092852 scopus 로고    scopus 로고
    • Qualitative and quantitative characterization of autophagy in Caenorhabditis elegans by electron microscopy
    • Sigmond T, Feher J, Baksa A, Pasti G, Palfia Z, Takacs-Vellai K et al. Qualitative and quantitative characterization of autophagy in Caenorhabditis elegans by electron microscopy. Methods Enzymol 2008; 451: 467-491.
    • (2008) Methods Enzymol , vol.451 , pp. 467-491
    • Sigmond, T.1    Feher, J.2    Baksa, A.3    Pasti, G.4    Palfia, Z.5    Takacs-Vellai, K.6
  • 52
    • 0034727876 scopus 로고    scopus 로고
    • Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: Possible role of vesicular transport in axonal elongation
    • Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y et al. Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation. Brain Res Mol Brain Res 2000; 85: 1-12.
    • (2000) Brain Res Mol Brain Res , vol.85 , pp. 1-12
    • Okazaki, N.1    Yan, J.2    Yuasa, S.3    Ueno, T.4    Kominami, E.5    Masuho, Y.6
  • 53
    • 77449094358 scopus 로고    scopus 로고
    • Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration
    • Liang CC, Wang C, Peng X, Gan B, Guan JL. Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration. J Biol Chem 2010; 285: 3499-3509.
    • (2010) J Biol Chem , vol.285 , pp. 3499-3509
    • Liang, C.C.1    Wang, C.2    Peng, X.3    Gan, B.4    Guan, J.L.5
  • 54
    • 0014828952 scopus 로고
    • Neuromuscular transmission in new-born rats
    • Redfern PA. Neuromuscular transmission in new-born rats. J Physiol 1970; 209: 701-709.
    • (1970) J Physiol , vol.209 , pp. 701-709
    • Redfern, P.A.1
  • 55
    • 0017716765 scopus 로고
    • The reorganization of synaptic connexions in the rat submandibular ganglion during post-natal development
    • Lichtman JW. The reorganization of synaptic connexions in the rat submandibular ganglion during post-natal development. J Physiol 1977; 273: 155-177.
    • (1977) J Physiol , vol.273 , pp. 155-177
    • Lichtman, J.W.1
  • 56
    • 0018910426 scopus 로고
    • The elimination of redundant preganglionic innervation to hamster sympathetic ganglion cells in early post-natal life
    • Lichtman JW, Purves D. The elimination of redundant preganglionic innervation to hamster sympathetic ganglion cells in early post-natal life. J Physiol 1980; 301: 213-228.
    • (1980) J Physiol , vol.301 , pp. 213-228
    • Lichtman, J.W.1    Purves, D.2
  • 57
    • 0017057659 scopus 로고
    • Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the Weaver Mutant Mouse
    • Crepel F, Mariani J. Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the Weaver Mutant Mouse. J Neurobiol 1976; 7: 579-582.
    • (1976) J Neurobiol , vol.7 , pp. 579-582
    • Crepel, F.1    Mariani, J.2
  • 58
    • 0030055566 scopus 로고    scopus 로고
    • Synapse elimination in the central nervous system: Functional significance and cellular mechanisms
    • Lohof AM, Delhaye-Bouchaud N, Mariani J. Synapse elimination in the central nervous system: functional significance and cellular mechanisms. Rev Neurosci 1996; 7: 85-101.
    • (1996) Rev Neurosci , vol.7 , pp. 85-101
    • Lohof, A.M.1    Delhaye-Bouchaud, N.2    Mariani, J.3
  • 59
    • 0034517718 scopus 로고    scopus 로고
    • Developmental remodeling of the retinogeniculate synapse
    • Chen C, Regehr WG. Developmental remodeling of the retinogeniculate synapse. Neuron 2000; 28: 955-966.
    • (2000) Neuron , vol.28 , pp. 955-966
    • Chen, C.1    Regehr, W.G.2
  • 60
    • 33646381622 scopus 로고    scopus 로고
    • Developmental remodelling of the lemniscal synapse in the ventral basal thalamus of the mouse
    • Arsenault D, Zhang ZW. Developmental remodelling of the lemniscal synapse in the ventral basal thalamus of the mouse. J Physiol 2006; 573(Pt 1): 121-132.
    • (2006) J Physiol , vol.573 , pp. 121-132
    • Arsenault, D.1    Zhang, Z.W.2
  • 62
    • 0037039358 scopus 로고    scopus 로고
    • A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
    • Tang SJ, Reis G, Kang H, Gingras AC, Sonenberg N, Schuman EM. A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus. Proc Natl Acad Sci USA 2002; 99: 467-472.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 467-472
    • Tang, S.J.1    Reis, G.2    Kang, H.3    Gingras, A.C.4    Sonenberg, N.5    Schuman, E.M.6
  • 63
    • 84876893671 scopus 로고    scopus 로고
    • FIP200 is required for maintenance and differentiation of postnatal neural stem cells
    • Wang C, Liang CC, Bian ZC, Zhu Y, Guan JL. FIP200 is required for maintenance and differentiation of postnatal neural stem cells. Nat Neurosci 2013; 16: 532-542.
    • (2013) Nat Neurosci , vol.16 , pp. 532-542
    • Wang, C.1    Liang, C.C.2    Bian, Z.C.3    Zhu, Y.4    Guan, J.L.5
  • 64
    • 84893116073 scopus 로고    scopus 로고
    • Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites
    • Brot S, Auger C, Bentata R, Rogemond V, Menigoz S, Chounlamountri N et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem 2014; 289: 2261-2276.
    • (2014) J Biol Chem , vol.289 , pp. 2261-2276
    • Brot, S.1    Auger, C.2    Bentata, R.3    Rogemond, V.4    Menigoz, S.5    Chounlamountri, N.6
  • 65
    • 84885176082 scopus 로고    scopus 로고
    • Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
    • Chu CT, Ji J, Dagda RK, Jiang JF, Tyurina YY, Kapralov AA et al. Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. Nat Cell Biol 2013; 15: 1197-1205.
    • (2013) Nat Cell Biol , vol.15 , pp. 1197-1205
    • Chu, C.T.1    Ji, J.2    Dagda, R.K.3    Jiang, J.F.4    Tyurina, Y.Y.5    Kapralov, A.A.6
  • 66
    • 84894293156 scopus 로고    scopus 로고
    • FOXO3 determines the accumulation of alpha-synuclein and controls the fate of dopaminergic neurons in the substantia nigra
    • Pino E, Amamoto R, Zheng L, Cacquevel M, Sarria JC, Knott GW et al. FOXO3 determines the accumulation of alpha-synuclein and controls the fate of dopaminergic neurons in the substantia nigra. Hum Mol Genet 2014; 23: 1435-1452.
    • (2014) Hum Mol Genet , vol.23 , pp. 1435-1452
    • Pino, E.1    Amamoto, R.2    Zheng, L.3    Cacquevel, M.4    Sarria, J.C.5    Knott, G.W.6
  • 68
    • 84886797274 scopus 로고    scopus 로고
    • Autophagy in infection, inflammation and immunity
    • Deretic V, Saitoh T, Akira S. Autophagy in infection, inflammation and immunity. Nat Rev Immunol 2013; 13: 722-737.
    • (2013) Nat Rev Immunol , vol.13 , pp. 722-737
    • Deretic, V.1    Saitoh, T.2    Akira, S.3
  • 70
    • 72449161077 scopus 로고    scopus 로고
    • Role of the arcuate nucleus of the hypothalamus in regulation of body weight during energy deficit
    • Sainsbury A, Zhang L. Role of the arcuate nucleus of the hypothalamus in regulation of body weight during energy deficit. Mol Cell Endocrinol 2010; 316: 109-119.
    • (2010) Mol Cell Endocrinol , vol.316 , pp. 109-119
    • Sainsbury, A.1    Zhang, L.2
  • 71
    • 84859952517 scopus 로고    scopus 로고
    • Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis
    • Thelen M, Damme M, Schweizer M, Hagel C, Wong AM, Cooper JD et al. Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis. PLoS One 2012; 7: e35493.
    • (2012) PLoS One , vol.7 , pp. e35493
    • Thelen, M.1    Damme, M.2    Schweizer, M.3    Hagel, C.4    Wong, A.M.5    Cooper, J.D.6
  • 72
    • 84870924926 scopus 로고    scopus 로고
    • Autophagy in astrocytes: A novel culprit in lysosomal storage disorders
    • Di Malta C, Fryer JD, Settembre C, Ballabio A. Autophagy in astrocytes: a novel culprit in lysosomal storage disorders. Autophagy 2012; 8: 1871-1872.
    • (2012) Autophagy , vol.8 , pp. 1871-1872
    • Di Malta, C.1    Fryer, J.D.2    Settembre, C.3    Ballabio, A.4
  • 75
    • 0035821438 scopus 로고    scopus 로고
    • Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease
    • German DC, Quintero EM, Liang CL, Ng B, Punia S, Xie C et al. Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease. J Comp Neurol 2001; 433: 415-425.
    • (2001) J Comp Neurol , vol.433 , pp. 415-425
    • German, D.C.1    Quintero, E.M.2    Liang, C.L.3    Ng, B.4    Punia, S.5    Xie, C.6
  • 77
    • 84868102987 scopus 로고    scopus 로고
    • Impaired proteolysis underlies autophagic dysfunction in Niemann-Pick type C disease
    • Elrick MJ, Yu T, Chung C, Lieberman AP. Impaired proteolysis underlies autophagic dysfunction in Niemann-Pick type C disease. Hum Mol Genet 2012; 21: 4876-4887.
    • (2012) Hum Mol Genet , vol.21 , pp. 4876-4887
    • Elrick, M.J.1    Yu, T.2    Chung, C.3    Lieberman, A.P.4
  • 78
    • 84866118530 scopus 로고    scopus 로고
    • Defective mitophagy in human Niemann-Pick type C1 neurons is due to abnormal autophagy activation
    • Ordonez MP. Defective mitophagy in human Niemann-Pick type C1 neurons is due to abnormal autophagy activation. Autophagy 2012; 8: 1157-1158.
    • (2012) Autophagy , vol.8 , pp. 1157-1158
    • Ordonez, M.P.1
  • 79
    • 84899957348 scopus 로고    scopus 로고
    • High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A
    • Gabande-Rodriguez E, Boya P, Labrador V, Dotti CG, Ledesma MD. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A. Cell Death Differ 2014; 21: 864-875.
    • (2014) Cell Death Differ , vol.21 , pp. 864-875
    • Gabande-Rodriguez, E.1    Boya, P.2    Labrador, V.3    Dotti, C.G.4    Ledesma, M.D.5
  • 81
    • 80655144753 scopus 로고    scopus 로고
    • Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy
    • Farkas T, Daugaard M, Jaattela M. Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy. J Biol Chem 2011; 286: 38904-38912.
    • (2011) J Biol Chem , vol.286 , pp. 38904-38912
    • Farkas, T.1    Daugaard, M.2    Jaattela, M.3
  • 82
    • 54349123772 scopus 로고    scopus 로고
    • Autophagic and apoptotic cell death in amniotic epithelial cells
    • Shen ZY, Li EM, Lu SQ, Shen J, Cai YM, Wu YE et al. Autophagic and apoptotic cell death in amniotic epithelial cells. Placenta 2008; 29: 956-961.
    • (2008) Placenta , vol.29 , pp. 956-961
    • Shen, Z.Y.1    Li, E.M.2    Lu, S.Q.3    Shen, J.4    Cai, Y.M.5    Wu, Y.E.6
  • 83
    • 77951171023 scopus 로고    scopus 로고
    • Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
    • Bonapace L, Bornhauser BC, Schmitz M, Cario G, Ziegler U, Niggli FK et al. Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. J Clin Invest 2010; 120: 1310-1323.
    • (2010) J Clin Invest , vol.120 , pp. 1310-1323
    • Bonapace, L.1    Bornhauser, B.C.2    Schmitz, M.3    Cario, G.4    Ziegler, U.5    Niggli, F.K.6
  • 84
    • 40849135481 scopus 로고    scopus 로고
    • The Sirtuin family: Therapeutic targets to treat diseases of aging
    • Milne JC, Denu JM. The Sirtuin family: therapeutic targets to treat diseases of aging. Curr Opin Chem Biol 2008; 12: 11-17.
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 11-17
    • Milne, J.C.1    Denu, J.M.2
  • 85
    • 84870999850 scopus 로고    scopus 로고
    • The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
    • Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G et al. The NAD-dependent deacetylase SIRT2 is required for programmed necrosis. Nature 2012; 492: 199-204.
    • (2012) Nature , vol.492 , pp. 199-204
    • Narayan, N.1    Lee, I.H.2    Borenstein, R.3    Sun, J.4    Wong, R.5    Tong, G.6
  • 86
    • 84859151852 scopus 로고    scopus 로고
    • PKD at the crossroads of necrosis and autophagy
    • Eisenberg-Lerner A, Kimchi A. PKD at the crossroads of necrosis and autophagy. Autophagy 2012; 8: 433-434.
    • (2012) Autophagy , vol.8 , pp. 433-434
    • Eisenberg-Lerner, A.1    Kimchi, A.2
  • 87
    • 34347234160 scopus 로고    scopus 로고
    • Protein kinase D1: A protein of emerging translational interest
    • Jaggi M, Du C, Zhang W, Balaji KC. Protein kinase D1: a protein of emerging translational interest. Front Biosci 2007; 12: 3757-3767.
    • (2007) Front Biosci , vol.12 , pp. 3757-3767
    • Jaggi, M.1    Du, C.2    Zhang, W.3    Balaji, K.C.4
  • 88
    • 79953765274 scopus 로고    scopus 로고
    • A one and a two expanding roles for poly(ADP-ribose) polymerases in metabolism
    • Luo X, Kraus WL. A one and a two expanding roles for poly(ADP-ribose) polymerases in metabolism. Cell Metab 2011; 13: 353-355.
    • (2011) Cell Metab , vol.13 , pp. 353-355
    • Luo, X.1    Kraus, W.L.2
  • 89
    • 2642536197 scopus 로고    scopus 로고
    • Alkylating DNA damage stimulates a regulated form of necrotic cell death
    • Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004; 18: 1272-1282.
    • (2004) Genes Dev , vol.18 , pp. 1272-1282
    • Zong, W.X.1    Ditsworth, D.2    Bauer, D.E.3    Wang, Z.Q.4    Thompson, C.B.5
  • 91
    • 84892575595 scopus 로고    scopus 로고
    • Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from 'liponecrosis', a previously unknown form of programmed cell death
    • Sheibani S, Richard VR, Beach A, Leonov A, Feldman R, Mattie S et al. Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from 'liponecrosis', a previously unknown form of programmed cell death. Cell Cycle 2014; 13: 138-147.
    • (2014) Cell Cycle , vol.13 , pp. 138-147
    • Sheibani, S.1    Richard, V.R.2    Beach, A.3    Leonov, A.4    Feldman, R.5    Mattie, S.6
  • 92
    • 13744255990 scopus 로고    scopus 로고
    • The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: Implications for necrosis initiation
    • Bianchi L, Gerstbrein B, Frokjaer-Jensen C, Royal DC, Mukherjee G, Royal MA et al. The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation. Nat Neurosci 2004; 7: 1337-1344.
    • (2004) Nat Neurosci , vol.7 , pp. 1337-1344
    • Bianchi, L.1    Gerstbrein, B.2    Frokjaer-Jensen, C.3    Royal, D.C.4    Mukherjee, G.5    Royal, M.A.6
  • 93
    • 36148960499 scopus 로고    scopus 로고
    • Induction of autophagy in neurite degeneration of mouse superior cervical ganglion neurons
    • Yang Y, Fukui K, Koike T, Zheng X. Induction of autophagy in neurite degeneration of mouse superior cervical ganglion neurons. Eur J Neurosci 2007; 26: 2979-2988.
    • (2007) Eur J Neurosci , vol.26 , pp. 2979-2988
    • Yang, Y.1    Fukui, K.2    Koike, T.3    Zheng, X.4
  • 94
    • 33644861728 scopus 로고    scopus 로고
    • ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function
    • Lange PF, Wartosch L, Jentsch TJ, Fuhrmann JC. ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function. Nature 2006; 440: 220-223.
    • (2006) Nature , vol.440 , pp. 220-223
    • Lange, P.F.1    Wartosch, L.2    Jentsch, T.J.3    Fuhrmann, J.C.4
  • 98
    • 84900460616 scopus 로고    scopus 로고
    • Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy
    • Zavodszky E, Seaman MN, Moreau K, Jimenez-Sanchez M, Breusegem SY, Harbour ME et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun 2014; 5: 3828.
    • (2014) Nat Commun , vol.5 , pp. 3828
    • Zavodszky, E.1    Seaman, M.N.2    Moreau, K.3    Jimenez-Sanchez, M.4    Breusegem, S.Y.5    Harbour, M.E.6
  • 99
    • 84881147729 scopus 로고    scopus 로고
    • Autophagic failure promotes the exocytosis and intercellular transfer of alpha-synuclein
    • Lee HJ, Cho ED, Lee KW, Kim JH, Cho SG, Lee SJ. Autophagic failure promotes the exocytosis and intercellular transfer of alpha-synuclein. Exp Mol Med 2013; 45: e22.
    • (2013) Exp Mol Med , vol.45 , pp. e22
    • Lee, H.J.1    Cho, E.D.2    Lee, K.W.3    Kim, J.H.4    Cho, S.G.5    Lee, S.J.6
  • 100
    • 69149089036 scopus 로고    scopus 로고
    • Molecular pathogenesis of Parkinson disease: Insights from genetic studies
    • Gasser T. Molecular pathogenesis of Parkinson disease: insights from genetic studies. Expert Rev Mol Med 2009; 11: e22.
    • (2009) Expert Rev Mol Med , vol.11 , pp. e22
    • Gasser, T.1
  • 102
    • 83455243339 scopus 로고    scopus 로고
    • Autophagy dysregulation in amyotrophic lateral sclerosis
    • Chen S, Zhang X, Song L, Le W. Autophagy dysregulation in amyotrophic lateral sclerosis. Brain Pathol 2012; 22: 110-116.
    • (2012) Brain Pathol , vol.22 , pp. 110-116
    • Chen, S.1    Zhang, X.2    Song, L.3    Le, W.4
  • 103
  • 104
    • 84873267192 scopus 로고    scopus 로고
    • Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process
    • Salminen A, Kaarniranta K, Kauppinen A. Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the aging process. Ageing Res Rev 2013; 12: 520-534.
    • (2013) Ageing Res Rev , vol.12 , pp. 520-534
    • Salminen, A.1    Kaarniranta, K.2    Kauppinen, A.3
  • 105
    • 84884185631 scopus 로고    scopus 로고
    • Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease
    • Lucin KM, O'Brien CE, Bieri G, Czirr E, Mosher KI, Abbey RJ et al. Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron 2013; 79: 873-886.
    • (2013) Neuron , vol.79 , pp. 873-886
    • Lucin, K.M.1    O'Brien, C.E.2    Bieri, G.3    Czirr, E.4    Mosher, K.I.5    Abbey, R.J.6
  • 106
    • 84885736277 scopus 로고    scopus 로고
    • Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy
    • Tian Y, Chang JC, Fan EY, Flajolet M, Greengard P. Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy. Proc Natl Acad Sci USA 2013; 110: 17071-17076.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 17071-17076
    • Tian, Y.1    Chang, J.C.2    Fan, E.Y.3    Flajolet, M.4    Greengard, P.5
  • 107
    • 84897386660 scopus 로고    scopus 로고
    • REST and stress resistance in ageing and Alzheimer's disease
    • Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y et al. REST and stress resistance in ageing and Alzheimer's disease. Nature 2014; 507: 448-454.
    • (2014) Nature , vol.507 , pp. 448-454
    • Lu, T.1    Aron, L.2    Zullo, J.3    Pan, Y.4    Kim, H.5    Chen, Y.6
  • 108
    • 80054825045 scopus 로고    scopus 로고
    • Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
    • Martinez J, Almendinger J, Oberst A, Ness R, Dillon CP, Fitzgerald P et al. Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells. Proc Natl Acad Sci USA 2011; 108: 17396-17401.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 17396-17401
    • Martinez, J.1    Almendinger, J.2    Oberst, A.3    Ness, R.4    Dillon, C.P.5    Fitzgerald, P.6
  • 109
    • 84901380438 scopus 로고    scopus 로고
    • Heterozygous ambra1 deficiency in mice: A genetic trait with autism-like behavior restricted to the female gender
    • Dere E, Dahm L, Lu D, Hammerschmidt K, Ju A, Tantra M et al. Heterozygous ambra1 deficiency in mice: a genetic trait with autism-like behavior restricted to the female gender. Front Behav Neurosci 2014; 8: 181.
    • (2014) Front Behav Neurosci , vol.8 , pp. 181
    • Dere, E.1    Dahm, L.2    Lu, D.3    Hammerschmidt, K.4    Ju, A.5    Tantra, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.