-
1
-
-
61349088546
-
Inflammation in Alzheimer’s disease: Amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors
-
Salminen A, Ojala J, Kauppinen A, Kaamiranta K, Suuronen T. Inflammation in Alzheimer’s disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors. Progr Neurobiol 2009; 87(3): 181-94.
-
(2009)
Progr Neurobiol
, vol.87
, Issue.3
, pp. 181-194
-
-
Salminen, A.1
Ojala, J.2
Kauppinen, A.3
Kaamiranta, K.4
Suuronen, T.5
-
2
-
-
77949940198
-
Intracellular toll-like receptors
-
Blasius AL, Beutler B. Intracellular toll-like receptors. Immunity 2010; 32(3): 305-15.
-
(2010)
Immunity
, vol.32
, Issue.3
, pp. 305-315
-
-
Blasius, A.L.1
Beutler, B.2
-
3
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010; 11(5): 373-84.
-
(2010)
Nat Immunol
, vol.11
, Issue.5
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
4
-
-
75849151435
-
Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptor-mediated neuronal injury
-
Lehnardt S. Innate immunity and neuroinflammation in the CNS: the role of microglia in Toll-like receptor-mediated neuronal injury. Glia 2010; 58(3): 253-63.
-
(2010)
Glia
, vol.58
, Issue.3
, pp. 253-263
-
-
Lehnardt, S.1
-
5
-
-
79960973055
-
Regulation of innate immune responses in the central nervous system
-
Bajramovic JJ. Regulation of innate immune responses in the central nervous system. CNS Neurol Disord Drug Targets 2011; 10(1): 4-24.
-
(2011)
CNS Neurol Disord Drug Targets
, vol.10
, Issue.1
, pp. 4-24
-
-
Bajramovic, J.J.1
-
6
-
-
81155130797
-
TLR2-9 crosstalk dictates IL-12 family cytokine production in microglia
-
Holley MM, Zhang Y, Lehrmann E, et al. TLR2-9 crosstalk dictates IL-12 family cytokine production in microglia. Glia 2012; 60(1): 29-42.
-
(2012)
Glia
, vol.60
, Issue.1
, pp. 29-42
-
-
Holley, M.M.1
Zhang, Y.2
Lehrmann, E.3
-
7
-
-
84864464545
-
Immune surveillance in the central nervous system
-
Ousman SS, Kubes P. Immune surveillance in the central nervous system. Nat Neurosci 2012; 15(8): 1096-101.
-
(2012)
Nat Neurosci
, vol.15
, Issue.8
, pp. 1096-1101
-
-
Ousman, S.S.1
Kubes, P.2
-
8
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002; 23(11): 549-55.
-
(2002)
Trends Immunol
, vol.23
, Issue.11
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
9
-
-
24744467358
-
Microglial phagocytosis induced by fibrillar Aβ and IgGs are differentially regulated by proinflammatory cytokines
-
Koenigsknecht-Talboo J, Landreth GE. Microglial phagocytosis induced by fibrillar Aβ and IgGs are differentially regulated by proinflammatory cytokines. J Neurosci 2005; 25(36): 8240-9.
-
(2005)
J Neurosci
, vol.25
, Issue.36
, pp. 8240-8249
-
-
Koenigsknecht-Talboo, J.1
Landreth, G.E.2
-
10
-
-
34547531201
-
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver receptors
-
Zelcer N, Khanlou N, Clare R, et al. Attenuation of neuroinflammation and Alzheimer's disease pathology by liver receptors. Proc Natl Acad Sci USA 2007; 104(25): 10601-6.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.25
, pp. 10601-10606
-
-
Zelcer, N.1
Khanlou, N.2
Clare, R.3
-
11
-
-
33847099936
-
Astrocytes are active players in cerebral innate immunity
-
Farina C, Aloisi F, Meinl E. Astrocytes are active players in cerebral innate immunity. Trends Immunol 2007; 28(3): 138-45.
-
(2007)
Trends Immunol
, vol.28
, Issue.3
, pp. 138-145
-
-
Farina, C.1
Aloisi, F.2
Meinl, E.3
-
12
-
-
0034612175
-
Inflammation and Alzheimer’s disease
-
Akiyama H, Barger S, Barnum S, et al. Inflammation and Alzheimer’s disease. Neurobiol Aging 2000; 21(3): 383-421.
-
(2000)
Neurobiol Aging
, vol.21
, Issue.3
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
-
13
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer’s amyloid β- peptide
-
Haass C, Selkoe DJ. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer’s amyloid β- peptide. Nat Rev Mol Cell Biol 2007; 8(2): 101-12
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.2
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
14
-
-
66449130960
-
Regulation of innate immune responses in the brain
-
Rivest S. Regulation of innate immune responses in the brain. Nat Rev Immunol 2009; 9(6): 383-421.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.6
, pp. 383-421
-
-
Rivest, S.1
-
15
-
-
78149245073
-
Role of inflammation in cognitive impairment: Results of observational epidemiological studies and clinical trials
-
Gorelick PB. Role of inflammation in cognitive impairment: results of observational epidemiological studies and clinical trials. Ann NY Acad Sci 2010; 1207: 155-62.
-
(2010)
Ann NY Acad Sci
, vol.1207
, pp. 155-162
-
-
Gorelick, P.B.1
-
16
-
-
57449111231
-
Immune defects in Alzheimer’s disease: New medications development
-
Cashman JR, Ghirmai S, Abel KJ, Fiala M. Immune defects in Alzheimer’s disease: new medications development. BMC Neurosci 2008; 9(2): S13.
-
(2008)
BMC Neurosci
, vol.9
, Issue.2
, pp. S13
-
-
Cashman, J.R.1
Ghirmai, S.2
Abel, K.J.3
Fiala, M.4
-
17
-
-
79952574501
-
Epidemiology of Alzheimer disease
-
Reitz C, Brayne C, Mayeux R. Epidemiology of Alzheimer disease. Nat Rev Neurol 2011; 7(3): 137-52.
-
(2011)
Nat Rev Neurol
, vol.7
, Issue.3
, pp. 137-152
-
-
Reitz, C.1
Brayne, C.2
Mayeux, R.3
-
18
-
-
28444442999
-
Adrian M, et al. 3D structure of Alzheimer's amyloidbeta (1-42) fibrils
-
Luhrs T, Ritter C, Adrian M, et al. 3D structure of Alzheimer's amyloidbeta (1-42) fibrils. Proc Natl Acad Sci USA 2005; 102(48): 17342-7.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.48
, pp. 17342-17347
-
-
Luhrs, T.1
Ritter, C.2
-
19
-
-
26444587508
-
Macroautophagy- a novel β- amyloid peptide-generating pathway activated in Alzheimer's disease
-
Yu WH, Cuervo AM, Kumar A, et al. Macroautophagy- a novel β- amyloid peptide-generating pathway activated in Alzheimer's disease. J Cell Biol 2005; 171(1): 87-98.
-
(2005)
J Cell Biol
, vol.171
, Issue.1
, pp. 87-98
-
-
Yu, W.H.1
Cuervo, A.M.2
Kumar, A.3
-
20
-
-
38349046973
-
Autophagy, amyloidogenesis and Alzheimer disease
-
Nixon RA. Autophagy, amyloidogenesis and Alzheimer disease. J Cell Sci 2007; 120: 4081-91.
-
(2007)
J Cell Sci
, vol.120
, pp. 4081-4091
-
-
Nixon, R.A.1
-
21
-
-
20244364226
-
Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice
-
Abbas N, Bednar I, Mix E, et al. Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice. J Neuroimmunol 2002; 126(1-2): 50-7.
-
(2002)
J Neuroimmunol
, vol.126
, Issue.1-2
, pp. 50-57
-
-
Abbas, N.1
Bednar, I.2
Mix, E.3
-
22
-
-
70349323417
-
CD14 and TLR2 and 4 are required for Fibrillar AβStimulated Microglial Activation
-
Reed-Geaghan EG, Savage JC, Hise AG, Landreth GE. CD14 and TLR2 and 4 are required for Fibrillar AβStimulated Microglial Activation. J Neurosci 2009; 29(38): 11982-92.
-
(2009)
J Neurosci
, vol.29
, Issue.38
, pp. 11982-11992
-
-
Reed-Geaghan, E.G.1
Savage, J.C.2
Hise, A.G.3
Landreth, G.E.4
-
23
-
-
33646484491
-
TLRs mediate IFNgamma production by human uterine NK cells in endometrium
-
Eriksson M, Meadows SK, Basu S, et al. TLRs mediate IFNgamma production by human uterine NK cells in endometrium. J Immunol 2006; 176(10): 6219-24.
-
(2006)
J Immunol
, vol.176
, Issue.10
, pp. 6219-6224
-
-
Eriksson, M.1
Meadows, S.K.2
Basu, S.3
-
24
-
-
33646147362
-
Toll-like receptors function and signaling
-
Kaisho T, Akira S. Toll-like receptors function and signaling. J Allergy Clin Immunol 2006; 117(5): 979-87.
-
(2006)
J Allergy Clin Immunol
, vol.117
, Issue.5
, pp. 979-987
-
-
Kaisho, T.1
Akira, S.2
-
25
-
-
33745653534
-
Roles of IL-18 in basophils and mast cells
-
Yoshimoto T, Nakanishi K. Roles of IL-18 in basophils and mast cells. Allergol Int 2006; 55(2): 105-13.
-
(2006)
Allergol Int
, vol.55
, Issue.2
, pp. 105-113
-
-
Yoshimoto, T.1
Nakanishi, K.2
-
26
-
-
34548411427
-
Regulating B-cell activation and survival in response to TLR signals
-
Gerondakis S, Grumont RJ, Banerjee A. Regulating B-cell activation and survival in response to TLR signals. Immunol Cell Biol 2007; 85(6): 471-5.
-
(2007)
Immunol Cell Biol
, vol.85
, Issue.6
, pp. 471-475
-
-
Gerondakis, S.1
Grumont, R.J.2
Banerjee, A.3
-
27
-
-
37749042401
-
Toll-like receptors (TLR)-based networks regulate neutrophilic inflammation in respiratory disease
-
Sabroe I, Whyte MK. Toll-like receptors (TLR)-based networks regulate neutrophilic inflammation in respiratory disease. Biochem Soc Trans 2007; 35(Pt 6): 1492-5.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1492-1495
-
-
Sabroe, I.1
Whyte, M.K.2
-
28
-
-
35648960415
-
Regulatory T cells and tolllike receptors: Regulating the regulators
-
Sutmuller R, Garritsen A, Adema GJ. Regulatory T cells and tolllike receptors: regulating the regulators. Ann Rheum Dis 2007; 66(S3): 91-5.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 91-95
-
-
Sutmuller, R.1
Garritsen, A.2
Adema, G.J.3
-
29
-
-
41549134095
-
Toll-like receptors in the respiratory system: Their roles in inflammation
-
Iwamura C, Nakayama T. Toll-like receptors in the respiratory system: their roles in inflammation. Curr Allergy Asthma Rep 2008; 8(1): 7-13.
-
(2008)
Curr Allergy Asthma Rep
, vol.8
, Issue.1
, pp. 7-13
-
-
Iwamura, C.1
Nakayama, T.2
-
30
-
-
38449114645
-
Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosis
-
Gibson FC 3rd, Ukai T, Genco CA. Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosis. Front Biosci 2008; 13: 2041-59.
-
(2008)
Front Biosci
, vol.13
, pp. 2041-2059
-
-
Gibson, F.C.1
Ukai, T.2
Genco, C.A.3
-
31
-
-
79952575531
-
Evaluating the role of Toll-like receptors in diseases of the central nervous system
-
Carty M, Bowie AG. Evaluating the role of Toll-like receptors in diseases of the central nervous system. Biochem Pharmacol 2011; 81(7): 825-37.
-
(2011)
Biochem Pharmacol
, vol.81
, Issue.7
, pp. 825-837
-
-
Carty, M.1
Bowie, A.G.2
-
32
-
-
4644232615
-
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
-
Olson JK, Miller SD. Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol 2004; 173(6): 3916-24.
-
(2004)
J Immunol
, vol.173
, Issue.6
, pp. 3916-3924
-
-
Olson, J.K.1
Miller, S.D.2
-
33
-
-
0042377367
-
Cultured astrocytes express toll-like receptors for bacterial products
-
Bowman CC, Rasley A, Tranguch SL, Marriott I. Cultured astrocytes express toll-like receptors for bacterial products. Glia 2003; 43(3): 281-91.
-
(2003)
Glia
, vol.43
, Issue.3
, pp. 281-291
-
-
Bowman, C.C.1
Rasley, A.2
Tranguch, S.L.3
Marriott, I.4
-
34
-
-
35649003133
-
Toll-like receptors in defense and damage of the central nervous system
-
Aravalli RN, Peterson PK, Lokensgard JR. Toll-like receptors in defense and damage of the central nervous system. J Neuroimmune Pharmacol 2007; 2(4): 297-312.
-
(2007)
J Neuroimmune Pharmacol
, vol.2
, Issue.4
, pp. 297-312
-
-
Aravalli, R.N.1
Peterson, P.K.2
Lokensgard, J.R.3
-
35
-
-
35348860696
-
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
-
Tang SC, Arumugam TV, Xu X, et al. Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci USA 2007; 104(34): 13798-803.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.34
, pp. 13798-13803
-
-
Tang, S.C.1
Arumugam, T.V.2
Xu, X.3
-
36
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF. A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci USA 1998; 95(2): 588-93.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.2
, pp. 588-593
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
37
-
-
34547231172
-
Toll-like receptors in inflammation, infection and cancer
-
Chen K, Huang J, Gong W, et al. Toll-like receptors in inflammation, infection and cancer. Int Immunopharmacol 2007; 7(10): 1271-85.
-
(2007)
Int Immunopharmacol
, vol.7
, Issue.10
, pp. 1271-1285
-
-
Chen, K.1
Huang, J.2
Gong, W.3
-
38
-
-
33845786018
-
Current and future drugs targeting one class of innate immunity receptors: The Toll-like receptors
-
Romagne F. Current and future drugs targeting one class of innate immunity receptors: the Toll-like receptors. Drug Discov Toda 2007; 12(1-2): 80-7.
-
(2007)
Drug Discov Toda
, vol.12
, Issue.1-2
, pp. 80-87
-
-
Romagne, F.1
-
39
-
-
37849014248
-
Toll-like receptors and immune regulation: Implications for cancer therapy
-
Wang RF, Miyahara Y, Wang HY. Toll-like receptors and immune regulation: implications for cancer therapy. Oncogene 2008; 27(2): 181-9.
-
(2008)
Oncogene
, vol.27
, Issue.2
, pp. 181-189
-
-
Wang, R.F.1
Miyahara, Y.2
Wang, H.Y.3
-
40
-
-
65349162278
-
Innate recognition of intracellular pathogens: Detection and activation of the first line of defense
-
Rasmussen SB, Reinert LS, Paludan SR. Innate recognition of intracellular pathogens: detection and activation of the first line of defense. APMIS 2009; 117(5-6): 323-7.
-
(2009)
APMIS
, vol.117
, Issue.5-6
, pp. 323-327
-
-
Rasmussen, S.B.1
Reinert, L.S.2
Paludan, S.R.3
-
41
-
-
34548550594
-
Collaboration between the innate immune receptors dectin-1: TLRs, and Nods
-
Underhill DM. Collaboration between the innate immune receptors dectin-1: TLRs, and Nods. Immunol Rev 2007; 219: 75-87.
-
(2007)
Immunol Rev
, vol.219
, pp. 75-87
-
-
Underhill, D.M.1
-
42
-
-
2142762520
-
TLRs: Differential adapter utilization by Toll-like receptors mediates TLR-specific patterns of gene expression
-
Vogel SN, Fitzgerald KA, Fenton MJ. TLRs: differential adapter utilization by Toll-like receptors mediates TLR-specific patterns of gene expression. Mol Interv 2003; 3(8): 466-77.
-
(2003)
Mol Interv
, vol.3
, Issue.8
, pp. 466-477
-
-
Vogel, S.N.1
Fitzgerald, K.A.2
Fenton, M.J.3
-
43
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124(4): 783-801.
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
44
-
-
48749128643
-
Structures of the Toll-like receptor family and its ligand complexes
-
Jin MS, Lee JO. Structures of the Toll-like receptor family and its ligand complexes. Immunity 2008; 29(2): 182-91.
-
(2008)
Immunity
, vol.29
, Issue.2
, pp. 182-191
-
-
Jin, M.S.1
Lee, J.O.2
-
45
-
-
51349158231
-
Signaling adaptors used by Toll-like receptors: An update
-
Kenny EF, O’Neill LA. Signaling adaptors used by Toll-like receptors: an update. Cytokine 2008; 43(3): 342-9.
-
(2008)
Cytokine
, vol.43
, Issue.3
, pp. 342-349
-
-
Kenny, E.F.1
O’neill, L.A.2
-
46
-
-
68749115366
-
Recent insights into the structure of Tolllike receptors and post-translational modifications of their associated signaling proteins
-
Carpenter S, O’Neill LA. Recent insights into the structure of Tolllike receptors and post-translational modifications of their associated signaling proteins. Biochem J 2009; 422(1): 1-10.
-
(2009)
Biochem J
, vol.422
, Issue.1
, pp. 1-10
-
-
Carpenter, S.1
O’neill, L.A.2
-
47
-
-
58049220364
-
Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling
-
Monie TP, Moncrieffe MC, Gay NJ. Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling. Immunol Rev 2009; 227(1): 161-75.
-
(2009)
Immunol Rev
, vol.227
, Issue.1
, pp. 161-175
-
-
Monie, T.P.1
Moncrieffe, M.C.2
Gay, N.J.3
-
48
-
-
79953890803
-
The structural biology of Toll-like receptors
-
Botos I, Segal DM, Davies DR. The structural biology of Toll-like receptors. Structure 2011; 19(4): 447-59.
-
(2011)
Structure
, vol.19
, Issue.4
, pp. 447-459
-
-
Botos, I.1
Segal, D.M.2
Davies, D.R.3
-
49
-
-
80053221916
-
The essential roles of Toll-like receptor signaling pathways in sterile inflammatory diseases
-
Lin Q, Fang D, Fang J, Su SB. The essential roles of Toll-like receptor signaling pathways in sterile inflammatory diseases. Int Immunopharmacol 2011; 11(10): 1422-32.
-
(2011)
Int Immunopharmacol
, vol.11
, Issue.10
, pp. 1422-1432
-
-
Lin, Q.1
Fang, D.2
Fang, J.3
Su, S.B.4
-
50
-
-
0034623798
-
Structure and function of Toll-like receptor proteins
-
Means TK, Golenbock DT, Fenton MJ. Structure and function of Toll-like receptor proteins. Life Sci 2000; 68(3): 241-58.
-
(2000)
Life Sci
, vol.68
, Issue.3
, pp. 241-258
-
-
Means, T.K.1
Golenbock, D.T.2
Fenton, M.J.3
-
52
-
-
0742324860
-
TLR signaling pathways
-
Takeda K, Akira S. TLR signaling pathways. Semin Immunol 2004; 16(1): 3-9.
-
(2004)
Semin Immunol
, vol.16
, Issue.1
, pp. 3-9
-
-
Takeda, K.1
Akira, S.2
-
53
-
-
36049033394
-
Signaling to NF-kappa B by Toll-like receptors
-
Kawai T, Akira S. Signaling to NF-kappa B by Toll-like receptors. Trends Mol Med 2007; 13(11): 460-9.
-
(2007)
Trends Mol Med
, vol.13
, Issue.11
, pp. 460-469
-
-
Kawai, T.1
Akira, S.2
-
54
-
-
34548459895
-
Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins
-
Watters TM, Kenny EF, O’Neill LA. Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins. Immunol Cell Biol 2007; 85(6): 411-9.
-
(2007)
Immunol Cell Biol
, vol.85
, Issue.6
, pp. 411-419
-
-
Watters, T.M.1
Kenny, E.F.2
O’neill, L.A.3
-
55
-
-
0036606913
-
Lipopolysaccharide recognition: CD14: TLRs and the LPS-activation cluster
-
Triantafilou M, Triantafilou K. Lipopolysaccharide recognition: CD14: TLRs and the LPS-activation cluster. Trends Immunol 2002; 23(6): 301-4.
-
(2002)
Trends Immunol
, vol.23
, Issue.6
, pp. 301-304
-
-
Triantafilou, M.1
Triantafilou, K.2
-
56
-
-
85038643581
-
Toll-like receptors in central nervous system glial inflammation and homeostasis
-
Kielian T. Toll-like receptors in central nervous system glial inflammation and homeostasis. J Virol 2006; 83(5): 11362-9.
-
(2006)
J Virol
, vol.83
, Issue.5
, pp. 11362-11369
-
-
Kielian, T.1
-
57
-
-
78449254879
-
Deletion of CD14 attenuates Alzheimer’s disease pathology by influencing the brain’s inflammatory milieu
-
Reed-Geaghan EG, Reed QW, Cramer PE, Landreth GE. Deletion of CD14 attenuates Alzheimer’s disease pathology by influencing the brain’s inflammatory milieu. J Neurosci 2010; 30(46): 15369-773.
-
(2010)
J Neurosci
, vol.30
, Issue.46
, pp. 15369-15773
-
-
Reed-Geaghan, E.G.1
Reed, Q.W.2
Cramer, P.E.3
Landreth, G.E.4
-
58
-
-
78649434143
-
CD14 is a coreceptor of Toll-like receptors 7 and 9
-
Baumann CL, Aspalter IM, Sharif O, et al. CD14 is a coreceptor of Toll-like receptors 7 and 9. J Exp Med 2010; 207(12): 2689-701.
-
(2010)
J Exp Med
, vol.207
, Issue.12
, pp. 2689-2701
-
-
Baumann, C.L.1
Aspalter, I.M.2
Sharif, O.3
-
59
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
Hoebe K, Georgel P, Rutschmann S, et al. CD36 is a sensor of diacylglycerides. Nature 2005; 433(7025): 523-7.
-
(2005)
Nature
, vol.433
, Issue.7025
, pp. 523-527
-
-
Hoebe, K.1
Georgel, P.2
Rutschmann, S.3
-
60
-
-
33750070631
-
Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting
-
Triantafilou M, Gamper FG, Haston RM, et al. Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting. J Biol Chem 2006; 281(4): 31002-11.
-
(2006)
J Biol Chem
, vol.281
, Issue.4
, pp. 31002-31011
-
-
Triantafilou, M.1
Gamper, F.G.2
Haston, R.M.3
-
61
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart CR, Stuart LM, Wilkinson K, et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol 2010; 11(2): 155-61.
-
(2010)
Nat Immunol
, vol.11
, Issue.2
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
-
62
-
-
33750369226
-
Toll-like receptors in systemic autoimmune disease
-
Marshak-Rothstein A. Toll-like receptors in systemic autoimmune disease. Nat Rev Immunol 2006; 6(11): 823-35.
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.11
, pp. 823-835
-
-
Marshak-Rothstein, A.1
-
63
-
-
58049200734
-
Innate immunity to pathogens: Diversity in receptors for microbial recognition
-
Akira S. Innate immunity to pathogens: diversity in receptors for microbial recognition. Immunol Rev 2009; 227(1): 5-8.
-
(2009)
Immunol Rev
, vol.227
, Issue.1
, pp. 5-8
-
-
Akira, S.1
-
64
-
-
84870839150
-
Purinergic regulation of inflammasome activation after central nervous system injury
-
Bernier LP. Purinergic regulation of inflammasome activation after central nervous system injury. J Gen Physiol 2012; 140(5): 571-5.
-
(2012)
J Gen Physiol
, vol.140
, Issue.5
, pp. 571-575
-
-
Bernier, L.P.1
-
65
-
-
84869047004
-
Modulation of pathogen recognition by autophagy
-
Oh JE, Lee HK. Modulation of pathogen recognition by autophagy. Front Immunol 2012; 3: 44.
-
(2012)
Front Immunol
, vol.3
, pp. 44
-
-
Oh, J.E.1
Lee, H.K.2
-
66
-
-
84862274742
-
Microglial scavenger receptors and their roles in the pathogenesis of Alzheimer’s disease
-
Wilkinson K, El Khoury J. Microglial scavenger receptors and their roles in the pathogenesis of Alzheimer’s disease. Int J Alz Dis 2012; 489456.
-
(2012)
Int J Alz Dis
, pp. 489456
-
-
Wilkinson, K.1
El Khoury, J.2
-
67
-
-
80054934482
-
Targeting Toll-like receptors: Emerging therapeutics for multiple sclerosis management
-
Gambuzza M, Licata N, Palella E, et al. Targeting Toll-like receptors: emerging therapeutics for multiple sclerosis management. J Neuroimmunol 2011; 239(1-2): 1-12.
-
(2011)
J Neuroimmunol
, vol.239
, Issue.1-2
, pp. 1-12
-
-
Gambuzza, M.1
Licata, N.2
Palella, E.3
-
68
-
-
0036841178
-
Broad expression of Toll-like receptors in the human central nervous system
-
Bsibsi M, Ravid R, Gveric D, van Noort JM. Broad expression of Toll-like receptors in the human central nervous system. J Neuropathol Exp Neurol 2002; 61(11): 1013-21.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, Issue.11
, pp. 1013-1021
-
-
Bsibsi, M.1
Ravid, R.2
Gveric, D.3
Van Noort, J.M.4
-
69
-
-
0036548360
-
The Toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS
-
Lehnardt S, Lachance C, Patrizi S, et al. The Toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS. J Neurosci 2002; 22(7): 2478-86
-
(2002)
J Neurosci
, vol.22
, Issue.7
, pp. 2478-2486
-
-
Lehnardt, S.1
Lachance, C.2
Patrizi, S.3
-
70
-
-
25444498280
-
TLR signaling tailors innate immune responses in human microglia and astrocytes
-
Jack CS, Arbour N, Manusow J, et al. TLR signaling tailors innate immune responses in human microglia and astrocytes. J Immunol 2005; 175(7): 4320-30.
-
(2005)
J Immunol
, vol.175
, Issue.7
, pp. 4320-4330
-
-
Jack, C.S.1
Arbour, N.2
Manusow, J.3
-
71
-
-
33745292215
-
A mechanism for neurodegeneration-induced by group B streptococci through activation of TLR2/MyD88 pathway in microglia
-
Lehnardt S, Henneke P, Lien E, et al. A mechanism for neurodegeneration-induced by group B streptococci through activation of TLR2/MyD88 pathway in microglia. J Immunol 2006; 177(1): 583-92.
-
(2006)
J Immunol
, vol.177
, Issue.1
, pp. 583-592
-
-
Lehnardt, S.1
Henneke, P.2
Lien, E.3
-
72
-
-
33644833702
-
Microglia recognize double-stranded RNA via TLR3
-
Town T, Jeng D, Alexopoulou L, Tan J, Flavell RA. Microglia recognize double-stranded RNA via TLR3. J Immunol 2006; 176(6): 3304-12.
-
(2006)
J Immunol
, vol.176
, Issue.6
, pp. 3304-3312
-
-
Town, T.1
Jeng, D.2
Alexopoulou, L.3
Tan, J.4
Flavell, R.A.5
-
73
-
-
33750601026
-
The innate immune facet of brain: Human neurons express TLR3 and sense viral dsRNA
-
Lafon M, Megret F, Lafage M, Prehaud C. The innate immune facet of brain: human neurons express TLR3 and sense viral dsRNA. J Mol Neurosci 2006; 29(3): 185-94.
-
(2006)
J Mol Neurosci
, vol.29
, Issue.3
, pp. 185-194
-
-
Lafon, M.1
Megret, F.2
Lafage, M.3
Prehaud, C.4
-
74
-
-
33750333015
-
Toll-like receptor 8 function as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis
-
Ma Y, Li J, Chiu I, et al. Toll-like receptor 8 function as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis. J Cell Biol 2006; 175(2): 209-15.
-
(2006)
J Cell Biol
, vol.175
, Issue.2
, pp. 209-215
-
-
Ma, Y.1
Li, J.2
Chiu, I.3
-
75
-
-
36348955676
-
Toll-like receptor 3 is a potent regulator of axonal growth in mammals
-
Cameron JS, Alexopoulou L, Sloane JA, et al. Toll-like receptor 3 is a potent regulator of axonal growth in mammals. J Neurosci 2007; 27(47): 13033-41.
-
(2007)
J Neurosci
, vol.27
, Issue.47
, pp. 13033-13041
-
-
Cameron, J.S.1
Alexopoulou, L.2
Sloane, J.A.3
-
76
-
-
34447503938
-
A critical role of TLR2 in nerve injury-induced spinal cord glial cell activation and pain hypersensitivity
-
Kim D, Kim MA, Cho IH, et al. A critical role of TLR2 in nerve injury-induced spinal cord glial cell activation and pain hypersensitivity. J Biol Chem 2007; 282(20): 14975-83.
-
(2007)
J Biol Chem
, vol.282
, Issue.20
, pp. 14975-14983
-
-
Kim, D.1
Kim, M.A.2
Cho, I.H.3
-
77
-
-
84871241311
-
Immune-neural connections how the immune system’s response to infectious agents influences behavior
-
McCusker RH, Kelley KW. Immune-neural connections how the immune system’s response to infectious agents influences behavior. J Exp Biol 2013; 216(Pt 1): 84-98.
-
(2013)
J Exp Biol
, vol.216
, pp. 84-98
-
-
McCusker, R.H.1
Kelley, K.W.2
-
78
-
-
57649166494
-
Eating the enemy within: Autophagy in infectious diseases
-
Overdahl A, Levine B. Eating the enemy within: autophagy in infectious diseases. Cell Death Differ 2009; 16(1): 57-69.
-
(2009)
Cell Death Differ
, vol.16
, Issue.1
, pp. 57-69
-
-
Overdahl, A.1
Levine, B.2
-
79
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 2010; 11(1): 55-62.
-
(2010)
Nat Immunol
, vol.11
, Issue.1
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
-
80
-
-
79961055797
-
Intracellular recognition of pathogens and autophagy as an innate immune host defence
-
Yano T, Kurata S. Intracellular recognition of pathogens and autophagy as an innate immune host defence. J Biochem 2011; 150(2): 143-9.
-
(2011)
J Biochem
, vol.150
, Issue.2
, pp. 143-149
-
-
Yano, T.1
Kurata, S.2
-
81
-
-
41149108108
-
Bacterial lipopolysaccharide regulates nociceptin in sensory neurons
-
Acosta C, Davies A. Bacterial lipopolysaccharide regulates nociceptin in sensory neurons. J Neurosci Res 2008; 86(5): 1077-86.
-
(2008)
J Neurosci Res
, vol.86
, Issue.5
, pp. 1077-1086
-
-
Acosta, C.1
Davies, A.2
-
82
-
-
33745077384
-
Immunobiology of Toll-like receptors: Emerging trends
-
Pandey S, Agrawal DK. Immunobiology of Toll-like receptors: emerging trends. Immunol Cell Biol 2006; 84(4): 333-41.
-
(2006)
Immunol Cell Biol
, vol.84
, Issue.4
, pp. 333-341
-
-
Pandey, S.1
Agrawal, D.K.2
-
83
-
-
40449097556
-
A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS
-
Lehnardt S, Schott E, Trimbuch T, et al. A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS. J Neurosci 2008; 28(10): 2320-31.
-
(2008)
J Neurosci
, vol.28
, Issue.10
, pp. 2320-2331
-
-
Lehnardt, S.1
Schott, E.2
Trimbuch, T.3
-
84
-
-
33947629255
-
Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
-
Miyake K. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin Immunol 2007; 19(1): 3-10.
-
(2007)
Semin Immunol
, vol.19
, Issue.1
, pp. 3-10
-
-
Miyake, K.1
-
85
-
-
70449657872
-
CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns
-
Liu Y, Chen GY, Zheng P. CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns. Trends Immunol 2009; 30(12): 557-61.
-
(2009)
Trends Immunol
, vol.30
, Issue.12
, pp. 557-561
-
-
Liu, Y.1
Chen, G.Y.2
Zheng, P.3
-
86
-
-
46749110462
-
Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemochine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization
-
Shimada M, Yanai Y, Okazaki T, et al. Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemochine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization. Development 2008; 135(11): 2001-11.
-
(2008)
Development
, vol.135
, Issue.11
, pp. 2001-2011
-
-
Shimada, M.1
Yanai, Y.2
Okazaki, T.3
-
87
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 2007; 13(5): 552-9.
-
(2007)
Nat Med
, vol.13
, Issue.5
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
88
-
-
77956394741
-
A clear and present danger: Endogenous ligands of Toll-like receptors
-
Sloane JA, Blitz D, Margolin Z, Vartarian T. A clear and present danger: endogenous ligands of Toll-like receptors. Neuromol Med 2010; 12(2): 149-63.
-
(2010)
Neuromol Med
, vol.12
, Issue.2
, pp. 149-163
-
-
Sloane, J.A.1
Blitz, D.2
Margolin, Z.3
Vartarian, T.4
-
89
-
-
41249102142
-
Toll-like receptors: Roles in neuroprotection?
-
Hanisch U-K, Johnson TV, Kipnis J. Toll-like receptors: roles in neuroprotection? Trends Neurosci 2008; 31(4): 176-82.
-
(2008)
Trends Neurosci
, vol.31
, Issue.4
, pp. 176-182
-
-
Hanisch, U.-K.1
Johnson, T.V.2
Kipnis, J.3
-
90
-
-
33750576993
-
Role of TLR signaling in Aβuptake and clearance
-
Tahara K, Kim HD, Jin JJ, et al. Role of TLR signaling in Aβuptake and clearance. Brain 2006; 129(Pt 11): 3006-19.
-
(2006)
Brain
, vol.129
, pp. 3006-3019
-
-
Tahara, K.1
Kim, H.D.2
Jin, J.J.3
-
91
-
-
2342525996
-
Regulation of phagosome maturation by signals from toll-like receptors
-
Blander JM, Medzhitov R. Regulation of phagosome maturation by signals from toll-like receptors. Science 2004; 304(5673): 1014-8.
-
(2004)
Science
, vol.304
, Issue.5673
, pp. 1014-1018
-
-
Blander, J.M.1
Medzhitov, R.2
-
92
-
-
0347285351
-
Toll-like Receptors induce a phagocytic gene program through p38
-
Doyle SE, O’Connell RM, Miranda GA, et al. Toll-like Receptors induce a phagocytic gene program through p38. J Exp Med 2004; 199(1): 81-90.
-
(2004)
J Exp Med
, vol.199
, Issue.1
, pp. 81-90
-
-
Doyle, S.E.1
O’connell, R.M.2
Miranda, G.A.3
-
93
-
-
4344583898
-
Involvement of macroautophagy in the dissolution of neuronal inclusions
-
Rideout HJ, Lang-Rolling I, Stefanis L. Involvement of macroautophagy in the dissolution of neuronal inclusions. Int J Biochem Cell Biol 2004; 36(12): 2551-62.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, Issue.12
, pp. 2551-2562
-
-
Rideout, H.J.1
Lang-Rolling, I.2
Stefanis, L.3
-
94
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, Nakamura K, Matsui M, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441(7095): 885-9.
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
-
95
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M, Waguri S, Chiba T, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441(7095): 880-4.
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
-
96
-
-
53549084325
-
Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?
-
Klionsky DJ, Elazar Z, Seglen PO, Rubinsztein DC. Does bafilomycin A1 block the fusion of autophagosomes with lysosomes? Autophagy 2008; 4(7): 849-950.
-
(2008)
Autophagy
, vol.4
, Issue.7
, pp. 849-950
-
-
Klionsky, D.J.1
Elazar, Z.2
Seglen, P.O.3
Rubinsztein, D.C.4
-
97
-
-
57749100267
-
MyD88 and TRIF target beclin 1 to trigger autophagy in macrophages
-
Shi CS, Kehrl JH. MyD88 and TRIF target beclin 1 to trigger autophagy in macrophages. J Biol Chem 2008; 283(48): 33175-82.
-
(2008)
J Biol Chem
, vol.283
, Issue.48
, pp. 33175-33182
-
-
Shi, C.S.1
Kehrl, J.H.2
-
98
-
-
33847652900
-
Autophagy and neurodegeneration: When the cleaning crew goes on strike
-
Martinez-Vicente M, Cuervo AM. Autophagy and neurodegeneration: when the cleaning crew goes on strike. Lancet Neurol 2007; 6(4): 352-61.
-
(2007)
Lancet Neurol
, vol.6
, Issue.4
, pp. 352-361
-
-
Martinez-Vicente, M.1
Cuervo, A.M.2
-
99
-
-
0032473968
-
Human CD14 mediates recognition and phagocytosis of apoptotic cells
-
Dewitt A, Moffatt OD, Raykundalia C, et al. Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature 1998; 392(6675): 505-9.
-
(1998)
Nature
, vol.392
, Issue.6675
, pp. 505-509
-
-
Dewitt, A.1
Moffatt, O.D.2
Raykundalia, C.3
-
100
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction
-
Takuma K, Fang F, Zhang W, et al. RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction. Proc Natl Acad Sci USA 2009; 106(47): 20021-6.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.47
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
-
101
-
-
77955604553
-
Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Aβ42 uptake and lysosomal trafficking
-
Fuentealba RA, Liu Q, Zhang J, et al. Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Aβ42 uptake and lysosomal trafficking. PLoS One 2010; 5(7): e11884.
-
(2010)
PLoS One
, vol.5
, Issue.7
, pp. e11884
-
-
Fuentealba, R.A.1
Liu, Q.2
Zhang, J.3
-
102
-
-
77956955758
-
The role of microglia in amyloid clearance from the AD brain
-
Lee CYD, Landreth GE. The role of microglia in amyloid clearance from the AD brain. J Neural Transm 2010; 117(8): 949-60.
-
(2010)
J Neural Transm
, vol.117
, Issue.8
, pp. 949-960
-
-
Lee, C.Y.D.1
Landreth, G.E.2
-
103
-
-
84872466790
-
Eat-me: Autophagy, phagocytosis, and reactive oxygen species signaling
-
Vernon PJ, Tang D. Eat-me: autophagy, phagocytosis, and reactive oxygen species signaling. Antioxid Redox Signal 2012; 18(6): 677-91.
-
(2012)
Antioxid Redox Signal
, vol.18
, Issue.6
, pp. 677-691
-
-
Vernon, P.J.1
Tang, D.2
-
104
-
-
42249115877
-
Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
-
Koprich JB, Reske-Nielsen C, Mithal P, Isacson O. Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease. J Neuroinflammation 2008; 5: 8.
-
(2008)
J Neuroinflammation
, vol.5
, pp. 8
-
-
Koprich, J.B.1
Reske-Nielsen, C.2
Mithal, P.3
Isacson, O.4
-
105
-
-
38549176239
-
The role of TLR activation in inflammation
-
Sabroe I, Parker LC, Dower SK, Whyte MK. The role of TLR activation in inflammation. J Pathol 2008; 214(2): 126-35.
-
(2008)
J Pathol
, vol.214
, Issue.2
, pp. 126-135
-
-
Sabroe, I.1
Parker, L.C.2
Dower, S.K.3
Whyte, M.K.4
-
106
-
-
78649745833
-
The tolllike receptor-3 agonist polyinosinic:Polycytidylic acid triggers nigrostriatal dopaminergic degeneration
-
Deleidi M, Hallett PJ, Koprich JB, Chung CY, Isacson O. The tolllike receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration. J Neurosci 2010; 30(48): 16091-101.
-
(2010)
J Neurosci
, vol.30
, Issue.48
, pp. 16091-16101
-
-
Deleidi, M.1
Hallett, P.J.2
Koprich, J.B.3
Chung, C.Y.4
Isacson, O.5
-
107
-
-
0034507950
-
A perspective on inflammation in Alzheimer’s disease
-
Rogers J, Shen Y. A perspective on inflammation in Alzheimer’s disease. Ann NY Acad Sci 2000; 924: 132-5.
-
(2000)
Ann NY Acad Sci
, vol.924
, pp. 132-135
-
-
Rogers, J.1
Shen, Y.2
-
108
-
-
79960887486
-
Systemic inflammation and Alzheimer’s disease
-
Holmes C, Butchart J. Systemic inflammation and Alzheimer’s disease. Biochem Soc Trans 2011; 39(4): 898-901.
-
(2011)
Biochem Soc Trans
, vol.39
, Issue.4
, pp. 898-901
-
-
Holmes, C.1
Butchart, J.2
-
109
-
-
77953143687
-
Inflammation in AD: Relevance to pathogenesis and therapy
-
Zotova E, Nicoll JA, Kalaria R, Holmes C, Boche D. Inflammation in AD: relevance to pathogenesis and therapy. Alzheimers Res Ther 2010; 2(1): 1.
-
(2010)
Alzheimers Res Ther
, vol.2
, Issue.1
, pp. 1
-
-
Zotova, E.1
Nicoll, J.A.2
Kalaria, R.3
Holmes, C.4
Boche, D.5
-
110
-
-
0025129231
-
Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease
-
Van Duijn CM, Hofman A, Nagelkerken L. Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease. Neurosci Lett 1990; 108(3): 350-4.
-
(1990)
Neurosci Lett
, vol.108
, Issue.3
, pp. 350-354
-
-
Van Duijn, C.M.1
Hofman, A.2
Nagelkerken, L.3
-
111
-
-
0030446007
-
Blood levels of histamine, IL-1 beta, and TNF-alpha in patients with mild to moderate Alzheimer disease
-
Alvarez XA, Franco A, Fernandez-Novoa L, Cacabelos R. Blood levels of histamine, IL-1 beta, and TNF-alpha in patients with mild to moderate Alzheimer disease. Mol Chem Neuropathol 1996; 29(2-3): 237-52.
-
(1996)
Mol Chem Neuropathol
, vol.29
, Issue.2-3
, pp. 237-252
-
-
Alvarez, X.A.1
Franco, A.2
Fernandez-Novoa, L.3
Cacabelos, R.4
-
112
-
-
0027955685
-
Serum tumor necrosis factor (TNF) in Alzheimer's disease and multi-infarct dementia
-
Cacabelos R, Alvarez XA, Franco-Maside A, Fernandez-Novoa L, Caamano J. Serum tumor necrosis factor (TNF) in Alzheimer's disease and multi-infarct dementia. Methods Find Exp Clin Pharmacol 1994; 16(4): 2-35.
-
(1994)
Methods Find Exp Clin Pharmacol
, vol.16
, Issue.4
, pp. 2-35
-
-
Cacabelos, R.1
Alvarez, X.A.2
Franco-Maside, A.3
Fernandez-Novoa, L.4
Caamano, J.5
-
113
-
-
21344445485
-
Decline of immune responsiveness: A pathogenetic factor in Alzheimer disease?
-
Richartz E, Stransky E, Baltra A, et al. Decline of immune responsiveness: a pathogenetic factor in Alzheimer disease? J Psychiatr Res 2005; 39(5): 535-43.
-
(2005)
J Psychiatr Res
, vol.39
, Issue.5
, pp. 535-543
-
-
Richartz, E.1
Stransky, E.2
Baltra, A.3
-
115
-
-
0033966340
-
Increased plasma levels of interleukin-1: Interleukin-6: And alphachymotrypsin in patients with Alzheimer’s disease: Peripheral inflammation or signals from the brain?
-
Licastro F, Pedrini S, Caputo L, et al. Increased plasma levels of interleukin-1: interleukin-6: and alphachymotrypsin in patients with Alzheimer’s disease: Peripheral inflammation or signals from the brain? J Neuroimmunol 2000; 103(1): 97-102.
-
(2000)
J Neuroimmunol
, vol.103
, Issue.1
, pp. 97-102
-
-
Licastro, F.1
Pedrini, S.2
Caputo, L.3
-
116
-
-
0034811403
-
Inflammatory markers in Alzheimer’s disease and multi-infarct dementia
-
De Luigi A, Fragiacomo C, Lucca U, et al. Inflammatory markers in Alzheimer’s disease and multi-infarct dementia. Mech Ageing Dev 2001; 122(16): 1985-95.
-
(2001)
Mech Ageing Dev
, vol.122
, Issue.16
, pp. 1985-1995
-
-
De Luigi, A.1
Fragiacomo, C.2
Lucca, U.3
-
117
-
-
0036966388
-
Peripheral inflammatory response in Alzheimer’s disease and multiinfarct dementia
-
De Luigi A, Pizzimenti S, Quadri P, et al. Peripheral inflammatory response in Alzheimer’s disease and multiinfarct dementia. Neurobiol Dis 2002; 11(2): 308-14.
-
(2002)
Neurobiol Dis
, vol.11
, Issue.2
, pp. 308-314
-
-
De Luigi, A.1
Pizzimenti, S.2
Quadri, P.3
-
118
-
-
33947709910
-
Plasma cytokines profile in older subjects with late onset Alzheimer’s disease or vascular dementia
-
Zuliani G, Ranzini M, Guerra G, et al. Plasma cytokines profile in older subjects with late onset Alzheimer’s disease or vascular dementia. J Psychiatr Res 2007; 41(8): 686-93.
-
(2007)
J Psychiatr Res
, vol.41
, Issue.8
, pp. 686-693
-
-
Zuliani, G.1
Ranzini, M.2
Guerra, G.3
-
119
-
-
41449104291
-
Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer’s disease
-
Bermejo P, Martí-Aragón S, Benedí J, et al. Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer’s disease. Immunol Lett 2008; 117(2): 198-202
-
(2008)
Immunol Lett
, vol.117
, Issue.2
, pp. 198-202
-
-
Bermejo, P.1
Martí-Aragón, S.2
Benedí, J.3
-
120
-
-
71749104020
-
TNF-alpha antibodies to periodontal bacteria discriminate between Alzheimer’s disease patients and normal subjects
-
Kamer AR, Craig RG, Pirraglia E, et al. TNF-alpha antibodies to periodontal bacteria discriminate between Alzheimer’s disease patients and normal subjects. J Neuroimmunol 2009; 216(1-2): 92-7.
-
(2009)
J Neuroimmunol
, vol.216
, Issue.1-2
, pp. 92-97
-
-
Kamer, A.R.1
Craig, R.G.2
Pirraglia, E.3
-
121
-
-
70349891988
-
Peripheral cytokines and chemokines in Alzheimer’s disease
-
Lee KS, Chung JH, Choi TK, et al. Peripheral cytokines and chemokines in Alzheimer’s disease. Dement Geriatr Cogn Disord 2009; 28(4): 281-7.
-
(2009)
Dement Geriatr Cogn Disord
, vol.28
, Issue.4
, pp. 281-287
-
-
Lee, K.S.1
Chung, J.H.2
Choi, T.K.3
-
122
-
-
79959955207
-
Neuroinflamm-aging and neurodegenerative diseases: An overview
-
Pizza V, Agresta A, D’Acunto CW, Festa M, Capasso A. Neuroinflamm-aging and neurodegenerative diseases: an overview. CNS Neurol Disord Drug Targets 2011; 10(5): 621-34.
-
(2011)
CNS Neurol Disord Drug Targets
, vol.10
, Issue.5
, pp. 621-634
-
-
Pizza, V.1
Agresta, A.2
D’acunto, C.W.3
Festa, M.4
Capasso, A.5
-
123
-
-
84860346308
-
Expression of immunohistochemical markers on microglia in Creutzeldt-Jakob disease and Alzheimer’s disease: Morphometric study and review of the literature
-
Woitera M, Sobów T, Kloszewska I, et al. Expression of immunohistochemical markers on microglia in Creutzeldt-Jakob disease and Alzheimer’s disease: morphometric study and review of the literature. Folia Neuropathol 2012; 50(1): 74-84.
-
(2012)
Folia Neuropathol
, vol.50
, Issue.1
, pp. 74-84
-
-
Woitera, M.1
Sobów, T.2
Kloszewska, I.3
-
125
-
-
2442533101
-
Inflammatory proteins in plasma and the risk of dementia: The Rotterdam study
-
Engelhart MJ, Geerlingsm MI, Meijer J, et al. Inflammatory proteins in plasma and the risk of dementia: the Rotterdam study. Arch Neurol 2004; 61(5): 668-72.
-
(2004)
Arch Neurol
, vol.61
, Issue.5
, pp. 668-672
-
-
Engelhart, M.J.1
Geerlingsm, M.I.2
Meijer, J.3
-
126
-
-
1642275616
-
Predictors of cognitive decline and mortality of aged people over a 10-year period
-
Tilvis RS, Kahonen-Vare MH, Jolkkonen J, et al. Predictors of cognitive decline and mortality of aged people over a 10-year period. J Gerontol A Biol Sci Med Sci 2004; 59(3): 268-74.
-
(2004)
J Gerontol A Biol Sci Med Sci
, vol.59
, Issue.3
, pp. 268-274
-
-
Tilvis, R.S.1
Kahonen-Vare, M.H.2
Jolkkonen, J.3
-
127
-
-
19344365429
-
Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: Systematic review and meta-analysis
-
Kuo HK, Yen CJ, Chang CH, et al. Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis. Lancet Neurol 2005; 4(6): 371-80.
-
(2005)
Lancet Neurol
, vol.4
, Issue.6
, pp. 371-380
-
-
Kuo, H.K.1
Yen, C.J.2
Chang, C.H.3
-
128
-
-
34249784822
-
Inflammatory markers and the risk of Alzheimer disease: The Framingham study
-
Tan ZS, Beiser AS, Vasan RS, et al. Inflammatory markers and the risk of Alzheimer disease: the Framingham study. Neurology 2007; 68(22): 1902-8.
-
(2007)
Neurology
, vol.68
, Issue.22
, pp. 1902-1908
-
-
Tan, Z.S.1
Beiser, A.S.2
Vasan, R.S.3
-
129
-
-
0141740742
-
Intrathecal inflammation precedes development of Alzheimer’s disease
-
Tarkowski E, Andreasen N, Tarkowski A, Blennow K. Intrathecal inflammation precedes development of Alzheimer’s disease. J Neurol Neurosurg Psychiatry 2003; 74(9): 1200-5.
-
(2003)
J Neurol Neurosurg Psychiatry
, vol.74
, Issue.9
, pp. 1200-1205
-
-
Tarkowski, E.1
Andreasen, N.2
Tarkowski, A.3
Blennow, K.4
-
130
-
-
42549130059
-
Intrathecal levels of IL-6: IL-11 and LIF in Alzheimer's disease and frontotemporal lobar degeneration
-
Galimberti D, Venturelli E, Fenoglio C, et al. Intrathecal levels of IL-6: IL-11 and LIF in Alzheimer's disease and frontotemporal lobar degeneration. J Neurol 2008; 255(4): 539-44.
-
(2008)
J Neurol
, vol.255
, Issue.4
, pp. 539-544
-
-
Galimberti, D.1
Venturelli, E.2
Fenoglio, C.3
-
131
-
-
55949104665
-
TNF signaling inhibition in the CNS: Implications for normal brain function and neurodegenerative disease
-
McCoy MK, Tansey MG. TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease. J Neuroinflammation 2008; 5: 45.
-
(2008)
J Neuroinflammation
, vol.5
, pp. 45
-
-
McCoy, M.K.1
Tansey, M.G.2
-
132
-
-
0031983986
-
Glial-neuronal interactions in Alzheimer's disease: The potential role of a 'cytokine cycle' in disease progression
-
Griffin WS, Sheng JG, Royston MC, et al. Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression. Brain Pathol 1998; 8(1): 65-72.
-
(1998)
Brain Pathol
, vol.8
, Issue.1
, pp. 65-72
-
-
Griffin, W.S.1
Sheng, J.G.2
Royston, M.C.3
-
133
-
-
27744464859
-
The microglial “activation” continuum: From innate to adaptive responses
-
Town T, Nikolic V, Tan J. The microglial “activation” continuum: from innate to adaptive responses. J Neuroinflammation 2005; 2: 24.
-
(2005)
J Neuroinflammation
, vol.2
, pp. 24
-
-
Town, T.1
Nikolic, V.2
Tan, J.3
-
134
-
-
4944258716
-
The role of inflammation in Alzheimer’s disease
-
Tuppo EE, Arias HR. The role of inflammation in Alzheimer’s disease. Int J Biochem Cell Biol 2005; 37(2): 289-305.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, Issue.2
, pp. 289-305
-
-
Tuppo, E.E.1
Arias, H.R.2
-
135
-
-
79955671043
-
Targeting oligomers in neurodegenerative disorders: Lessons from α-synuclein, tau, and amyloid-β peptide
-
Gadad BS, Britton GB, Rao KS. Targeting oligomers in neurodegenerative disorders: lessons from α-synuclein, tau, and amyloid-β peptide. J Alzheimers Dis 2011; 24(Suppl 2): 223-32.
-
(2011)
J Alzheimers Dis
, vol.24
, pp. 223-232
-
-
Gadad, B.S.1
Britton, G.B.2
Rao, K.S.3
-
136
-
-
0035950225
-
Clearing the brain’s amyloid cobwebs
-
Selkoe DJ. Clearing the brain’s amyloid cobwebs. Neuron 2001; 32(2): 177-80.
-
(2001)
Neuron
, vol.32
, Issue.2
, pp. 177-180
-
-
Selkoe, D.J.1
-
137
-
-
36248957122
-
Mechanisms of A beta mediated neurodegeneration in Alzheimer’s disease
-
Crouch PJ, Harding SM, White AR, et al. Mechanisms of A beta mediated neurodegeneration in Alzheimer’s disease. Int J Biochem Cell Biol 2008; 40(2): 181-98.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, Issue.2
, pp. 181-198
-
-
Crouch, P.J.1
Harding, S.M.2
White, A.R.3
-
140
-
-
32844465483
-
Cytokine production by a human microglial cell line: Effects of β-amyloid and α-melanocyte-stimulating hormone
-
Lindberg C, Hjorth E, Post C, Winblad B, Schultzberg M. Cytokine production by a human microglial cell line: effects of β-amyloid and α-melanocyte-stimulating hormone. Neurotox Res 2005; 8(3- 4): 267-76.
-
(2005)
Neurotox Res
, vol.8
, Issue.3-4
, pp. 267-276
-
-
Lindberg, C.1
Hjorth, E.2
Post, C.3
Winblad, B.4
Schultzberg, M.5
-
141
-
-
0033951505
-
Alzheimer’s disease and inflammation: A review of cellular and therapeutic mechanisms
-
Halliday G, Robinson SR, Shepherd C, Kril J. Alzheimer’s disease and inflammation: a review of cellular and therapeutic mechanisms. Clin Exp Pharmacol Physiol 2000; 27(1-2): 1-8.
-
(2000)
Clin Exp Pharmacol Physiol
, vol.27
, Issue.1-2
, pp. 1-8
-
-
Halliday, G.1
Robinson, S.R.2
Shepherd, C.3
Kril, J.4
-
142
-
-
0041784698
-
Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
-
Brown GC, Bal-Price A. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol Neurobiol 2003; 27(3): 325-55.
-
(2003)
Mol Neurobiol
, vol.27
, Issue.3
, pp. 325-355
-
-
Brown, G.C.1
Bal-Price, A.2
-
143
-
-
84861078831
-
A rewiev: Inflammatory process in Alzheimer's disease, role of cytokines
-
Rubio-Perez JM, Morillaz-Ruiz JM. A rewiev: inflammatory process in Alzheimer's disease, role of cytokines. Sci World J 2012; 756357.
-
(2012)
Sci World J
, pp. 756357
-
-
Rubio-Perez, J.M.1
Morillaz-Ruiz, J.M.2
-
144
-
-
80053930850
-
The regulation of the CNS innate immune response is vital for the restoration of tissue homeostasis (repair) after acute brain injury: A brief review
-
Griffiths MR, Gasque P, Neal JW. The regulation of the CNS innate immune response is vital for the restoration of tissue homeostasis (repair) after acute brain injury: a brief review. Int J Inflam 2010; 151097.
-
(2010)
Int J Inflam
, pp. 151097
-
-
Griffiths, M.R.1
Gasque, P.2
Neal, J.W.3
-
145
-
-
56349166514
-
Mechanisms of microglia accumulation in Alzheimer’s disease: Therapeutic implications
-
El Khoury J, Luster AD. Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications. Trends Pharmacol Sci 2008; 29(12): 626-32.
-
(2008)
Trends Pharmacol Sci
, vol.29
, Issue.12
, pp. 626-632
-
-
El Khoury, J.1
Luster, A.D.2
-
146
-
-
66349120877
-
Autophagy protects neuron from Aβ-induced neurotoxicity
-
Hung S-Y, Wang W-P, Liou H-C, Fu W-M. Autophagy protects neuron from Aβ-induced neurotoxicity. Autophagy 2009; 5(4): 502-10.
-
(2009)
Autophagy
, vol.5
, Issue.4
, pp. 502-510
-
-
Hung, S.-Y.1
Wang, W.-P.2
Liou, H.-C.3
Fu, W.-M.4
-
147
-
-
84857058225
-
Control of autophagy as a therapy for neurodegenerative disease
-
Harris H, Rubinsztein DC. Control of autophagy as a therapy for neurodegenerative disease. Nat Rev Neurol 2011; 8(2): 108-17.
-
(2011)
Nat Rev Neurol
, vol.8
, Issue.2
, pp. 108-117
-
-
Harris, H.1
Rubinsztein, D.C.2
-
148
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
-
Nixon RA, Wegiel J, Kumar A, et al. Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J Neuropathol Exp Neurol 2005; 64(2): 113-22.
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, Issue.2
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
-
149
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer’s disease
-
Boland B, Kumar A, Lee S, et al. Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer’s disease. J Neurosci 2008; 28(27): 6926-37.
-
(2008)
J Neurosci
, vol.28
, Issue.27
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
-
150
-
-
34447636918
-
Phagocytosis of amyloid-beta and inflammation: Two faces of innate immunity in Alzheimer’s disease
-
Fiala M, Cribbs DH, Rosenthal M, Bernard G. Phagocytosis of amyloid-beta and inflammation: two faces of innate immunity in Alzheimer’s disease. J Alzheimers Dis 2007; 11(4): 457-63.
-
(2007)
J Alzheimers Dis
, vol.11
, Issue.4
, pp. 457-463
-
-
Fiala, M.1
Cribbs, D.H.2
Rosenthal, M.3
Bernard, G.4
-
151
-
-
79957490240
-
Monocytes in Alzheimer’s Disease
-
Feng Y, Li L. Monocytes in Alzheimer’s Disease. Neurosci Bull 2011; 27(2): 115-22.
-
(2011)
Neurosci Bull
, vol.27
, Issue.2
, pp. 115-122
-
-
Feng, Y.1
Li, L.2
-
152
-
-
84866734401
-
Inflammation and neurodegeneration: The story “retolled
-
Drouin-Quellet J, Cicchetti F. Inflammation and neurodegeneration: the story “retolled”. Trends Pharmacol Sci 2012; 33(10): 542-51.
-
(2012)
Trends Pharmacol Sci
, vol.33
, Issue.10
, pp. 542-551
-
-
Drouin-Quellet, J.1
Cicchetti, F.2
-
153
-
-
3242803587
-
Nonsteroidal antiinflammatory drugs for the prevention of AD
-
Szekely CA, Thorne JE, Zandi PP, et al. Nonsteroidal antiinflammatory drugs for the prevention of AD. Neuroepidemiology 2004; 23(4): 159-69.
-
(2004)
Neuroepidemiology
, vol.23
, Issue.4
, pp. 159-169
-
-
Szekely, C.A.1
Thorne, J.E.2
Zandi, P.P.3
-
154
-
-
85038643816
-
-
Northwestern University. www.northwestern.edu/newscenter/storie s/2012/07/brain-inflamation-drug.html
-
-
-
-
155
-
-
62349114515
-
Screening of innate immune receptors in neurodegenerative diseases: A similar pattern
-
Letiembre M, Liu Y, Walter S, et al. Screening of innate immune receptors in neurodegenerative diseases: a similar pattern. Neurobiol Aging 2009; 30(5): 759-68.
-
(2009)
Neurobiol Aging
, vol.30
, Issue.5
, pp. 759-768
-
-
Letiembre, M.1
Liu, Y.2
Walter, S.3
-
156
-
-
42649098547
-
Microglial degeneration in the aging brain-bad news for neurons?
-
Streit WJ, Miller KR, Lopes KO, Njie E. Microglial degeneration in the aging brain-bad news for neurons? Front Biosci 2008; 13: 3423-38.
-
(2008)
Front Biosci
, vol.13
, pp. 3423-3438
-
-
Streit, W.J.1
Miller, K.R.2
Lopes, K.O.3
Njie, E.4
-
157
-
-
35848963223
-
Role of the toll-like receptor 4 in neuroinflammation in Alzheimer’s disease
-
Walter J, Schulz-Schuffer W, Fassbender K. Role of the toll-like receptor 4 in neuroinflammation in Alzheimer’s disease. Cell Physiol Biochem 2007; 20(6): 947-56.
-
(2007)
Cell Physiol Biochem
, vol.20
, Issue.6
, pp. 947-956
-
-
Walter, J.1
Schulz-Schuffer, W.2
Fassbender, K.3
-
158
-
-
33747388358
-
Lysosomal system pathways: Genes to neurodegeneration in Alzheimer’s disease
-
Nixon RA, Cataldo AM. Lysosomal system pathways: genes to neurodegeneration in Alzheimer’s disease. J Alzheimers Dis 2006; 9(3 Suppl): 277-89.
-
(2006)
J Alzheimers Dis
, vol.9
, Issue.3
, pp. 277-289
-
-
Nixon, R.A.1
Cataldo, A.M.2
-
159
-
-
84874998766
-
The Ubiquitin- Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease
-
Ihara Y, Maho Morishima-Kawashima M, Nixon R. The Ubiquitin- Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease. Cold Spring Harb Perspect Med 2012; 2(8): 006361.
-
(2012)
Cold Spring Harb Perspect Med
, Issue.8
, pp. 2
-
-
Ihara, Y.1
Maho Morishima-Kawashima, M.2
Nixon, R.3
-
160
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, Homung V, Petzold GC, et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol 2008; 9(8): 857-65.
-
(2008)
Nat Immunol
, vol.9
, Issue.8
, pp. 857-865
-
-
Halle, A.1
Homung, V.2
Petzold, G.C.3
-
161
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
Davis BK, Wen H, Ting JPY. The inflammasome NLRs in immunity, inflammation, and associated diseases. Ann Rev Immunol 2011; 29: 707-35.
-
(2011)
Ann Rev Immunol
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, P.Y.3
-
162
-
-
58149181978
-
Fibrillar amyloid-β peptides activate microglia via TLR2: Implications for Alzheimer’s disease
-
Jana M, Palencia CA, Pahan K. Fibrillar amyloid-β peptides activate microglia via TLR2: implications for Alzheimer’s disease. J Immunol 2008; 181(10): 7254-62.
-
(2008)
J Immunol
, vol.181
, Issue.10
, pp. 7254-7262
-
-
Jana, M.1
Palencia, C.A.2
Pahan, K.3
-
163
-
-
1342332161
-
The LPS receptor (CD14) links innate immunity with Alzheimer’s disease
-
Fassbender K, Walter S, Kühl S, et al. The LPS receptor (CD14) links innate immunity with Alzheimer’s disease. FASEB J 2004; 18(1): 203-5.
-
(2004)
FASEB J
, vol.18
, Issue.1
, pp. 203-205
-
-
Fassbender, K.1
Walter, S.2
Kühl, S.3
-
164
-
-
23444448277
-
LPS receptor (CD14): A receptor for phagocytosis of Alzheimer's amyloid peptide
-
Liu Y, Walter S, Stagi M, et al. LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide. Brain 2005; 128(Pt 8): 1778-89.
-
(2005)
Brain
, vol.128
, pp. 1778-1789
-
-
Liu, Y.1
Walter, S.2
Stagi, M.3
-
165
-
-
34447643958
-
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity
-
Xu Y, Jagannath C, Liu XD, et al. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 2007; 27(1): 135-44.
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 135-144
-
-
Xu, Y.1
Jagannath, C.2
Liu, X.D.3
-
166
-
-
41949101594
-
TLR control autophagy
-
Delgado MA, Elmaoued RA, Davis AS, Kyei G, Deretic V. TLR control autophagy. EMBO 2008; 27(7): 1110-21.
-
(2008)
EMBO
, vol.27
, Issue.7
, pp. 1110-1121
-
-
Delgado, M.A.1
Elmaoued, R.A.2
Davis, A.S.3
Kyei, G.4
Deretic, V.5
-
167
-
-
45949106077
-
Toll-like receptor 2 acts as a natural innate immune receptor to clear Aβ(1-42) and delay the cognitive decline in a mouse model of Alzheimer disease
-
Richard KL, Filali M, Préfontaine P, Rivest S. Toll-like receptor 2 acts as a natural innate immune receptor to clear Aβ(1-42) and delay the cognitive decline in a mouse model of Alzheimer disease. J Neurosci 2008; 28(22): 5784-93.
-
(2008)
J Neurosci
, vol.28
, Issue.22
, pp. 5784-5793
-
-
Richard, K.L.1
Filali, M.2
Préfontaine, P.3
Rivest, S.4
-
168
-
-
37349069999
-
Toll-like receptors 2 and 4 mediate Aβ(1-42) activation of the innate immune response in a human monocytic cell line
-
Udan ML, Ajit D, Crouse NR, Nichols MR. Toll-like receptors 2 and 4 mediate Aβ(1-42) activation of the innate immune response in a human monocytic cell line. J Neurochem 2008; 104(2): 524-33.
-
(2008)
J Neurochem
, vol.104
, Issue.2
, pp. 524-533
-
-
Udan, M.L.1
Ajit, D.2
Crouse, N.R.3
Nichols, M.R.4
-
169
-
-
84865578627
-
Additive microglialmediated neuronal injury caused by amyloid-βand bacterial TLR agonists in murine neuron-microglia co-coltures quantified by an automated image analysis using cognition network technology
-
Schütze S, Loleit T, Zeretzke M, et al. Additive microglialmediated neuronal injury caused by amyloid-βand bacterial TLR agonists in murine neuron-microglia co-coltures quantified by an automated image analysis using cognition network technology. J Alzheimers Dis 2012; 31(3): 651-7.
-
(2012)
J Alzheimers Dis
, vol.31
, Issue.3
, pp. 651-657
-
-
Schütze, S.1
Loleit, T.2
Zeretzke, M.3
-
170
-
-
77956802559
-
Toll-Like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: Towards future therapeutic application
-
Trudler D, Farfara D, Frenkel D. Toll-Like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic application. Mediators Inflamm 2010; 497987.
-
(2010)
Mediators Inflamm
, pp. 497987
-
-
Trudler, D.1
Farfara, D.2
Frenkel, D.3
-
171
-
-
84862295506
-
Sweepers in the CNS: Microglial migration and phagocytosis in the Alzheimer disease pathogenesis
-
Noda M, Suzumura A. Sweepers in the CNS: microglial migration and phagocytosis in the Alzheimer disease pathogenesis. Int J Alzheimers Dis 2012; 891087.
-
(2012)
Int J Alzheimers Dis
, pp. 891087
-
-
Noda, M.1
Suzumura, A.2
-
172
-
-
0033575761
-
Internalization of monomeric lipopolysaccharide occurs after transfer out of cell surface CD14
-
Vasselon T, Hailman E, Thieringer R, Detmers PA. Internalization of monomeric lipopolysaccharide occurs after transfer out of cell surface CD14. J Exp Med 1999; 190(4): 509-21.
-
(1999)
J Exp Med
, vol.190
, Issue.4
, pp. 509-521
-
-
Vasselon, T.1
Hailman, E.2
Thieringer, R.3
Detmers, P.A.4
-
173
-
-
0036774947
-
CD14 signaling in lipid rafts: New ligands and co-receptors
-
Schmitz G, Orsó E. CD14 signaling in lipid rafts: new ligands and co-receptors. Curr Opin Lipidol 2002; 13(5): 513-21.
-
(2002)
Curr Opin Lipidol
, vol.13
, Issue.5
, pp. 513-521
-
-
Schmitz, G.1
Orsó, E.2
-
174
-
-
0032767781
-
CD14 and apoptosis
-
Gregory CD, Devitt A. CD14 and apoptosis. Apoptosis 1999; 4(1): 11-20.
-
(1999)
Apoptosis
, vol.4
, Issue.1
, pp. 11-20
-
-
Gregory, C.D.1
Devitt, A.2
-
175
-
-
3142655659
-
Microglia kill Aβ(1-42) damaged neurons by a CD14-dependent process
-
Bate C, Veerhuis R, Eikelenboom P, Williams A. Microglia kill Aβ(1-42) damaged neurons by a CD14-dependent process. Neuroreport 2004; 15(9): 1427-30.
-
(2004)
Neuroreport
, vol.15
, Issue.9
, pp. 1427-1430
-
-
Bate, C.1
Veerhuis, R.2
Eikelenboom, P.3
Williams, A.4
-
176
-
-
85038642713
-
TLR4-dependent up-regulation of cytokines in a transgenic mouse model of Alzheimer’s disease
-
Jin JJ, Kim HD, Maxwell JA, Li L, Fukuchi K. TLR4-dependent up-regulation of cytokines in a transgenic mouse model of Alzheimer’s disease. J Neuroinflammation 2008; 29: 5-23.
-
(2008)
J Neuroinflammation
, vol.29
, pp. 5-23
-
-
Jin, J.J.1
Kim, H.D.2
Maxwell, J.A.3
Li, L.4
Fukuchi, K.5
-
177
-
-
30744441143
-
Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells
-
Bate C, Kempster S, Williams A. Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. Neuropharmacology 2006; 50(2): 229-37.
-
(2006)
Neuropharmacology
, vol.50
, Issue.2
, pp. 229-237
-
-
Bate, C.1
Kempster, S.2
Williams, A.3
-
178
-
-
37349032870
-
Glial toll-like receptor signaling in central nervous system infection and autoimmunity
-
Carpentier PA, Duncan DS, Miller SD. Glial toll-like receptor signaling in central nervous system infection and autoimmunity. Brain Behav Immun 2008; 22(2): 140-7.
-
(2008)
Brain Behav Immun
, vol.22
, Issue.2
, pp. 140-147
-
-
Carpentier, P.A.1
Duncan, D.S.2
Miller, S.D.3
-
179
-
-
0037387147
-
A cell surface receptor complex for fibrillar β-amyloid mediates microglial activation
-
Bamberger ME, Harris ME, McDonald DR, Husemann J, Landreth GE. A cell surface receptor complex for fibrillar β-amyloid mediates microglial activation. J Neurosci 2003; 23(7): 2665-74.
-
(2003)
J Neurosci
, vol.23
, Issue.7
, pp. 2665-2674
-
-
Bamberger, M.E.1
Harris, M.E.2
McDonald, D.R.3
Husemann, J.4
Landreth, G.E.5
-
180
-
-
7744235869
-
Microglial phagocytosis of fibrillar Aβ-amyloid through a β1 integrin-dependent mechanism
-
Koenigsknecht J, Landreth GE. Microglial phagocytosis of fibrillar Aβ-amyloid through a β1 integrin-dependent mechanism. J Neurosci 2004; 24(44): 9838-46.
-
(2004)
J Neurosci
, vol.24
, Issue.44
, pp. 9838-9846
-
-
Koenigsknecht, J.1
Landreth, G.E.2
-
181
-
-
65849327576
-
Raft aggregation with specific receptors recruitment is required for microglial phagocytosis of Aβ42
-
Persaud-Sawin DA, Banach L, Harry J. Raft aggregation with specific receptors recruitment is required for microglial phagocytosis of Aβ42. Glia 2009; 57(3): 320-35.
-
(2009)
Glia
, vol.57
, Issue.3
, pp. 320-335
-
-
Persaud-Sawin, D.A.1
Banach, L.2
Harry, J.3
-
182
-
-
0346003785
-
A CD36-initiated signaling cascade mediates inflammatory effects of β-amyloid
-
Moore KJ, El Khoury J, Medeiros LA, et al. A CD36-initiated signaling cascade mediates inflammatory effects of β-amyloid. J Biol Chem 2002; 277(49): 47373-9.
-
(2002)
J Biol Chem
, vol.277
, Issue.49
, pp. 47373-47379
-
-
Moore, K.J.1
El Khoury, J.2
Medeiros, L.A.3
-
183
-
-
0038204838
-
CD36 mediates the innate host response to β-amyloid
-
El Khoury J, Moore KJ, Means TK, et al. CD36 mediates the innate host response to β-amyloid. J Exp Med 2003; 197(12): 1657-66.
-
(2003)
J Exp Med
, vol.197
, Issue.12
, pp. 1657-1666
-
-
El Khoury, J.1
Moore, K.J.2
Means, T.K.3
-
184
-
-
0034674421
-
Role of CD47 as a marker of self on red blood cells
-
Oldenborg PA, Zheleznyak A, Fang YF, et al. Role of CD47 as a marker of self on red blood cells. Science 2000; 288(5473): 2051-4.
-
(2000)
Science
, vol.288
, Issue.5473
, pp. 2051-2054
-
-
Oldenborg, P.A.1
Zheleznyak, A.2
Fang, Y.F.3
-
185
-
-
67650468281
-
Amyloid beta peptides trigger CD47-dependent mast cell secretory and phagocytic responses
-
Niederhoffer N, Lew R, Sick E, et al. Amyloid beta peptides trigger CD47-dependent mast cell secretory and phagocytic responses. Int J Immunopathol Pharmacol 2009; 22(2): 473-83.
-
(2009)
Int J Immunopathol Pharmacol
, vol.22
, Issue.2
, pp. 473-483
-
-
Niederhoffer, N.1
Lew, R.2
Sick, E.3
-
186
-
-
45949103746
-
Cooperation between NOD2 and TLR2 ligands in the up-regulation of mouse mFPR2: A G-protein coupled Abeta42 peptide receptor in microglial cells
-
Chen K, Zhang L, Huang J, et al. Cooperation between NOD2 and TLR2 ligands in the up-regulation of mouse mFPR2: a G-protein coupled Abeta42 peptide receptor in microglial cells. J Leukoc Biol 2008; 83(6): 1467-75.
-
(2008)
J Leukoc Biol
, vol.83
, Issue.6
, pp. 1467-1475
-
-
Chen, K.1
Zhang, L.2
Huang, J.3
-
187
-
-
49349097868
-
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal
-
Tang SC, Lathia JD, Selvaraj PK, et al. Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Exp Neurol 2008; 213(1): 114-21.
-
(2008)
Exp Neurol
, vol.213
, Issue.1
, pp. 114-121
-
-
Tang, S.C.1
Lathia, J.D.2
Selvaraj, P.K.3
-
188
-
-
1842477469
-
mRNA is an endogenous ligand for Toll-like receptor 3
-
Kariko K, Ni H, Capodici J, Lamphier M, Weissmann D. mRNA is an endogenous ligand for Toll-like receptor 3. J Biol Chem 2004; 279(13): 12542-50.
-
(2004)
J Biol Chem
, vol.279
, Issue.13
, pp. 12542-12550
-
-
Kariko, K.1
Ni, H.2
Capodici, J.3
Lamphier, M.4
Weissmann, D.5
-
189
-
-
65249108735
-
Autophagy genes in immunity
-
Virgin HW, Levine B. Autophagy genes in immunity. Nat Immunol 2009; 10(5): 461-70.
-
(2009)
Nat Immunol
, vol.10
, Issue.5
, pp. 461-470
-
-
Virgin, H.W.1
Levine, B.2
-
190
-
-
70349570588
-
Systemic inflammation and disease progression in Alzheimer disease
-
Holmes C, Cunningham C, Zotova E, et al. Systemic inflammation and disease progression in Alzheimer disease. Neurology 2009; 73(10): 768-74.
-
(2009)
Neurology
, vol.73
, Issue.10
, pp. 768-774
-
-
Holmes, C.1
Cunningham, C.2
Zotova, E.3
-
191
-
-
77954218298
-
Systemic challenge with TLR3 agonist poly I:C induces amplified IFNα/βand IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration
-
Field R, Campion S, Warren C, Murray C, Cunningham C. Systemic challenge with TLR3 agonist poly I:C induces amplified IFNα/βand IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration. Brain Behav Immun 2010; 24(6): 996-1007.
-
(2010)
Brain Behav Immun
, vol.24
, Issue.6
, pp. 996-1007
-
-
Field, R.1
Campion, S.2
Warren, C.3
Murray, C.4
Cunningham, C.5
-
192
-
-
0033044565
-
Predominance of neuronal mRNAs in individualAlzheimer’s disease senile plaques
-
Ginsberg SD, Crino PB, Hemby SE, et al. Predominance of neuronal mRNAs in individualAlzheimer’s disease senile plaques. Ann Neurol 1999; 45(2): 174-81.
-
(1999)
Ann Neurol
, vol.45
, Issue.2
, pp. 174-181
-
-
Ginsberg, S.D.1
Crino, P.B.2
Hemby, S.E.3
-
193
-
-
0036707495
-
BetaAPP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients
-
Marcinkiewicz M. BetaAPP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients. J Neuropathol Exp Neurol 2002; 61(9): 815-29.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, Issue.9
, pp. 815-829
-
-
Marcinkiewicz, M.1
-
194
-
-
84861577379
-
An unconventional role for miRNA: Let-7 activates Toll-like receptor 7 and causes neurodegeneration
-
Lehmann SM, Krüger C, Park B, et al. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat Neurosci 2012; 15(6): 827-35.
-
(2012)
Nat Neurosci
, vol.15
, Issue.6
, pp. 827-835
-
-
Lehmann, S.M.1
Krüger, C.2
Park, B.3
-
195
-
-
73649137143
-
Microglia activated with the TLR9 ligand CpG attenuate oligomeric amyloid β neurotoxicity in vitro and in vivo models of Alzheimer’s disease
-
Doy Y, Mizuno T, Maki Y, et al. Microglia activated with the TLR9 ligand CpG attenuate oligomeric amyloid β neurotoxicity in vitro and in vivo models of Alzheimer’s disease. Am J Pathol 2009; 175(5): 2121-32.
-
(2009)
Am J Pathol
, vol.175
, Issue.5
, pp. 2121-2132
-
-
Doy, Y.1
Mizuno, T.2
Maki, Y.3
-
196
-
-
60849137841
-
Induction of TLR9 as a method for ameliorating AD-related pathology
-
Scholtzova H, Kascsak R., Bates KA, et al. Induction of TLR9 as a method for ameliorating AD-related pathology. J Neurosci 2009; 29(6): 1846-54.
-
(2009)
J Neurosci
, vol.29
, Issue.6
, pp. 1846-1854
-
-
Scholtzova, H.1
Kascsak, R.2
Bates, K.A.3
-
197
-
-
0037093870
-
Immunostimulatory CpGDNA activates murine microglia
-
Dalpke A, Schäfer M, Frey M, et al. Immunostimulatory CpGDNA activates murine microglia. J Immunol 2002; 168(10): 4854-63.
-
(2002)
J Immunol
, vol.168
, Issue.10
, pp. 4854-4863
-
-
Dalpke, A.1
Schäfer, M.2
Frey, M.3
-
198
-
-
71349087314
-
CpG-ODNs induces upregulated expression of chemokine CCL9 in mouse macrophages and microglia
-
Ravindran C, Chengm YC, Liang SM. CpG-ODNs induces upregulated expression of chemokine CCL9 in mouse macrophages and microglia. Cell Immunol 2010; 260(2): 113-8.
-
(2010)
Cell Immunol
, vol.260
, Issue.2
, pp. 113-118
-
-
Ravindran, C.1
Chengm, Y.C.2
Liang, S.M.3
-
199
-
-
33646463619
-
Immune system’s Toll-like receptors have good opportunity for cancer treatment
-
Schmidt C. Immune system’s Toll-like receptors have good opportunity for cancer treatment. J Natl Cancer Inst 2006; 98(9): 574-5.
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.9
, pp. 574-575
-
-
Schmidt, C.1
-
200
-
-
72049122659
-
Drugs targeting Toll like receptors
-
Krishnan J, Lee G. Drugs targeting Toll like receptors. Arch Pharm Res 2009; 32(11): 1485-502.
-
(2009)
Arch Pharm Res
, vol.32
, Issue.11
, pp. 1485-1502
-
-
Krishnan, J.1
Lee, G.2
-
201
-
-
84867520059
-
Targeting neuroinflammation for therapeutic intervention in neurodegenerative pathologies: A role for the peptide analogue of thymulin (PAT)
-
Safieh-Garabedian B, Mayasi Y, Saadé NE. Targeting neuroinflammation for therapeutic intervention in neurodegenerative pathologies: a role for the peptide analogue of thymulin (PAT). Expert Opin Ther Targets 2012; 16(11): 1065-73.
-
(2012)
Expert Opin Ther Targets
, vol.16
, Issue.11
, pp. 1065-1073
-
-
Safieh-Garabedian, B.1
Mayasi, Y.2
Saadé, N.E.3
-
202
-
-
84862331908
-
Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer’s disease: Randomised, double-blind, placebo-controlled, first-in-human study
-
Winblad B, Andreasen N, Minthon L, et al. Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer’s disease: randomised, double-blind, placebo-controlled, first-in-human study. Lancet Neurol 2012; 11(7): 597-604.
-
(2012)
Lancet Neurol
, vol.11
, Issue.7
, pp. 597-604
-
-
Winblad, B.1
Andreasen, N.2
Minthon, L.3
-
203
-
-
84920562402
-
-
(accessed August 30: 2013)
-
InvivoGen. Innovation within Reach. http://www.invivogen.com/ review-vaccine-adjuvants (accessed August 30: 2013).
-
-
-
-
204
-
-
77957982756
-
Toll-like receptor agonists: Are they good adjuvants?
-
Gnjatic S, Sawhney NB, Bhardwaj N. Toll-like receptor agonists: are they good adjuvants? Cancer J 2010; 16(4): 382-91.
-
(2010)
Cancer J
, vol.16
, Issue.4
, pp. 382-391
-
-
Gnjatic, S.1
Sawhney, N.B.2
Bhardwaj, N.3
-
205
-
-
84855184185
-
Prophylactic and therapeutic implications of Toll-like receptor ligands
-
Hedayat M, Takeda K, Rezaei N. Prophylactic and therapeutic implications of Toll-like receptor ligands. Med Res Rev 2012; 32(2): 294-325.
-
(2012)
Med Res Rev
, vol.32
, Issue.2
, pp. 294-325
-
-
Hedayat, M.1
Takeda, K.2
Rezaei, N.3
-
206
-
-
35348922783
-
Stabilized immune modulatory RNA compound as agonists of TLR7 and 8
-
Lan T, Kandimalla DY, Bhagat L, et al. Stabilized immune modulatory RNA compound as agonists of TLR7 and 8. Proc Natl Acad Sci USA 2007; 104(34): 13750-5.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.34
, pp. 13750-13755
-
-
Lan, T.1
Kandimalla, D.Y.2
Bhagat, L.3
-
207
-
-
45849112914
-
Role of neutrophils in BCG immunotherapy for bladder cancer
-
Simon MP, O’Donnell MA. Role of neutrophils in BCG immunotherapy for bladder cancer. Urol Oncol 2008; 26(4): 341-5.
-
(2008)
Urol Oncol
, vol.26
, Issue.4
, pp. 341-345
-
-
Simon, M.P.1
O’donnell, M.A.2
-
208
-
-
78751474671
-
Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells
-
Lu H, Yang Y, Gad E, et al. Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells. Clin Cancer Res 2011; 17(1): 67-76.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.1
, pp. 67-76
-
-
Lu, H.1
Yang, Y.2
Gad, E.3
-
209
-
-
77954904799
-
Identification of novel synthetic toll-like receptor 2 agonists by high throughput screening
-
Guan Y, Omueti-Ayoade K, Mutha SK, Hergenrother PJ, Tapping RI. Identification of novel synthetic toll-like receptor 2 agonists by high throughput screening. J Biol Chem 2010; 285(31): 23755-62.
-
(2010)
J Biol Chem
, vol.285
, Issue.31
, pp. 23755-23762
-
-
Guan, Y.1
Omueti-Ayoade, K.2
Mutha, S.K.3
Hergenrother, P.J.4
Tapping, R.I.5
-
210
-
-
34250854079
-
The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
-
Mata-Haro V, Cekic C, Martin M, et al. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science 2007; 316(5831): 1628-32.
-
(2007)
Science
, vol.316
, Issue.5831
, pp. 1628-1632
-
-
Mata-Haro, V.1
Cekic, C.2
Martin, M.3
-
211
-
-
53849109907
-
Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant
-
Casella CR, Mitchell TC. Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant. Cell Mol Life Sci 2008; 65(20): 3231-40.
-
(2008)
Cell Mol Life Sci
, vol.65
, Issue.20
, pp. 3231-3240
-
-
Casella, C.R.1
Mitchell, T.C.2
-
212
-
-
33947187647
-
Toll-free vaccines
-
Krieg AM. Toll-free vaccines. Nat Biotechnol 2007; 25(3): 303-5.
-
(2007)
Nat Biotechnol
, vol.25
, Issue.3
, pp. 303-305
-
-
Krieg, A.M.1
-
213
-
-
56349127390
-
Intracutaneous injection of the macrophage-activating lipopeptide- 2 (MALP-2) which accelerates wound healing in mice a phase I trial in 12 patients
-
Niebuhr M, Mühlradt PF, Wittmann M, Kapp A, Werfel T. Intracutaneous injection of the macrophage-activating lipopeptide- 2 (MALP-2) which accelerates wound healing in mice a phase I trial in 12 patients. Exp Dermatol 2008; 17(12): 1052-6.
-
(2008)
Exp Dermatol
, vol.17
, Issue.12
, pp. 1052-1056
-
-
Niebuhr, M.1
Mühlradt, P.F.2
Wittmann, M.3
Kapp, A.4
Werfel, T.5
-
214
-
-
34247331022
-
Cancer relapse under chemotherapy: Why TLR2/4 receptor agonists can help
-
Garay RP, Viens P, Bauer J, et al. Cancer relapse under chemotherapy: why TLR2/4 receptor agonists can help. Eur J Pharmacol 2007; 563(1-3): 1-17.
-
(2007)
Eur J Pharmacol
, vol.563
, Issue.1-3
, pp. 1-17
-
-
Garay, R.P.1
Viens, P.2
Bauer, J.3
-
215
-
-
33846213140
-
Translational Mini-Review Series on Toll-like Receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders
-
Goldman M. Translational Mini-Review Series on Toll-like Receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders. Clin Exp Immunol 2007; 147(2): 208-16.
-
(2007)
Clin Exp Immunol
, vol.147
, Issue.2
, pp. 208-216
-
-
Goldman, M.1
-
216
-
-
27244449289
-
Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-smallcell lung cancer
-
Butts C, Murray N, Maksymiuk A, et al. Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-smallcell lung cancer. J Clin Oncol 2005; 23(27): 6674-81.
-
(2005)
J Clin Oncol
, vol.23
, Issue.27
, pp. 6674-6681
-
-
Butts, C.1
Murray, N.2
Maksymiuk, A.3
-
217
-
-
0034123135
-
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
-
Muzio M, Bosisio D, Polentarutti N, et al. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J Immunol 2000; 164(11): 5998-6004.
-
(2000)
J Immunol
, vol.164
, Issue.11
, pp. 5998-6004
-
-
Muzio, M.1
Bosisio, D.2
Polentarutti, N.3
-
218
-
-
0037080024
-
Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
-
Zarember KA, Godowski PJ. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 2002; 168(2): 554-61.
-
(2002)
J Immunol
, vol.168
, Issue.2
, pp. 554-561
-
-
Zarember, K.A.1
Godowski, P.J.2
-
219
-
-
37549051320
-
Immunoadjuvant effects of polyadenylic:Polyuridylic acids through TLR3 and TLR7
-
Sugiyama T, Hoshino K, Saito M, et al. Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7. Int Immunol 2008; 20(1): 1-9.
-
(2008)
Int Immunol
, vol.20
, Issue.1
, pp. 1-9
-
-
Sugiyama, T.1
Hoshino, K.2
Saito, M.3
-
220
-
-
67349117313
-
Ampligen: A potential toll-like 3 receptor adjuvant for immunotherapy of cancer
-
Jasani B, Navabi H, Adams M. Ampligen: a potential toll-like 3 receptor adjuvant for immunotherapy of cancer. Vaccine 2009; 27(25-26): 3401-4.
-
(2009)
Vaccine
, vol.27
, Issue.25-26
, pp. 3401-3404
-
-
Jasani, B.1
Navabi, H.2
Adams, M.3
-
221
-
-
85038653851
-
-
Hemispherx Biopharma, Inc. Available from: http://www.hemi spherx.net/content/investor/default.asp?goto=339; 93 (accessed June 02, 2008).
-
-
-
-
222
-
-
85038645954
-
-
Nventa Biopharmaceutical Corp Safety study of HspE7 and Poly- ICLC given in patients with cervical intraepithelial neoplasia. Available from: http://clinicaltrials.gov/ct2/show/NCT00493545? term=Nventa&rank=2.html (accessed August IPH 28, 2013).
-
-
-
-
223
-
-
85038653338
-
-
3102-TLR3 agonist- Targeted oncology therapeutic agent. Available from: http://www.innate-pharma.com/rna-targeting-tlr (accessed April 02, 2009).
-
-
-
-
225
-
-
84920562758
-
-
(accessed March 12, 2007
-
R & D Focus Drug News. CQ 07001 TNO, Clinquest licensing agreement. Available from: http://www.highbeam.com/doc/1G1- 161564190.html (accessed March 12, 2007).
-
CQ 07001 TNO, Clinquest licensing agreement
-
-
-
227
-
-
67650064587
-
Autophagy-mediated anti-tumoral activity of Imiquimod in Caco-2 cells
-
Yi J, Jung YJ, Choi S., Hwang J, Chung E. Autophagy-mediated anti-tumoral activity of Imiquimod in Caco-2 cells. Biochem Biophys Res Commun 2009; 386(3): 455-8.
-
(2009)
Biochem Biophys Res Commun
, vol.386
, Issue.3
, pp. 455-458
-
-
Yi, J.1
Jung, Y.J.2
Choi, S.3
Hwang, J.4
Chung, E.5
-
228
-
-
77957680668
-
The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice
-
Ma F, Zhang J, Zhang J, Zhang C. The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice. Cell Mol Immunol 2010; 7(5): 381-8.
-
(2010)
Cell Mol Immunol
, vol.7
, Issue.5
, pp. 381-388
-
-
Ma, F.1
Zhang, J.2
Zhang, J.3
Zhang, C.4
-
229
-
-
34447632621
-
Pharmacokinetics of 852A, an imidazoquinoline Toll-like receptor 7-specific agonist, following intravenous, subcutaneous, and oral administrations in humans
-
Harrison LI, Astry C, Kumar S, Yunis C. Pharmacokinetics of 852A, an imidazoquinoline Toll-like receptor 7-specific agonist, following intravenous, subcutaneous, and oral administrations in humans. J Clin Pharmacol 2007; 47(8): 962-9.
-
(2007)
J Clin Pharmacol
, vol.47
, Issue.8
, pp. 962-969
-
-
Harrison, L.I.1
Astry, C.2
Kumar, S.3
Yunis, C.4
-
230
-
-
79960554471
-
Randomised clinical trial anti-viral activity of ANA 773: An oral inducer of exogenous interferons acting via TLR7: In chronic HCV
-
Bergmann JF, de Bruijne J, Hotho DM, et al. Randomised clinical trial anti-viral activity of ANA 773: an oral inducer of exogenous interferons acting via TLR7: in chronic HCV. Aliment Pharmacol Ther 2011; 34(4): 443-53.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, Issue.4
, pp. 443-453
-
-
Bergmann, J.F.1
De Bruijne, J.2
Hotho, D.M.3
-
231
-
-
85038652798
-
IMO-4200; a novel TLR7 and TLR8 dual agonist, enhances antitumor effect of ofatumumab, rituximab and cytotoxics in preclinical models of hematological malignancies
-
Wang D, Procopio M, Reardon M, et al. IMO-4200; a novel TLR7 and TLR8 dual agonist, enhances antitumor effect of ofatumumab, rituximab and cytotoxics in preclinical models of hematological malignancies. Idera Pharmaceutical Inc 2001; 3724.
-
(2001)
Idera Pharmaceutical Inc
, pp. 3724
-
-
Wang, D.1
Procopio, M.2
Reardon, M.3
-
235
-
-
67650487106
-
Phase II study of a TLR- 9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma
-
Friedberg JW, Kelly JL, Neuberg D, et al. Phase II study of a TLR- 9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. Br J Haematol 2009; 146(3): 282-91.
-
(2009)
Br J Haematol
, vol.146
, Issue.3
, pp. 282-291
-
-
Friedberg, J.W.1
Kelly, J.L.2
Neuberg, D.3
-
236
-
-
61749098024
-
Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
-
Vollmer J, Krieg AM. Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists. Adv Drug Deliv Rev 2009; 61(3): 195-204.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.3
, pp. 195-204
-
-
Vollmer, J.1
Krieg, A.M.2
-
237
-
-
63849177560
-
Vaccine adjuvants scientific challenges and strategic initiatives
-
Harandi AM, Davies G, Olesen OF. Vaccine adjuvants scientific challenges and strategic initiatives. Expert Rev Vaccines 2009; 8(3): 293-8.
-
(2009)
Expert Rev Vaccines
, vol.8
, Issue.3
, pp. 293-298
-
-
Harandi, A.M.1
Davies, G.2
Olesen, O.F.3
-
238
-
-
85038642068
-
Focus on cancer therapies
-
Mologen AG. Focus on cancer therapies. DNA-based therapy as the main driver. Available from: http://s3.amazonaws.com/zanran_ storage/www.mologen.com/ContentPages/46175022.pdf (accessed July 10, 2009).
-
DNA-based therapy as the main driver
-
-
Mologen, A.G.1
-
239
-
-
85047690873
-
Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes
-
Meng G, Rutz M, Schiemann M, et al. Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes. J Clin Invest 2004; 113(10): 1473-81.
-
(2004)
J Clin Invest
, vol.113
, Issue.10
, pp. 1473-1481
-
-
Meng, G.1
Rutz, M.2
Schiemann, M.3
-
240
-
-
47149084387
-
Bridging innate immunity and myocardial ischemia/reperfusion in injury: The search for therapeutic targets
-
Arslan F, de Kielijn DP, Timmers L, Doevendands PA, Pasterkamp G. Bridging innate immunity and myocardial ischemia/reperfusion in injury: the search for therapeutic targets. Curr Pharm Des 2008; 14(12): 1205-16.
-
(2008)
Curr Pharm Des
, vol.14
, Issue.12
, pp. 1205-1216
-
-
Arslan, F.1
De Kielijn, D.P.2
Timmers, L.3
Doevendands, P.A.4
Pasterkamp, G.5
-
241
-
-
70349342913
-
Identification and characterization of oligonucleotides that inhibit Toll-like receptor 2-associated immune responses
-
Chang YC, Kao WC, Wang WY, Yang RB, Peck K. Identification and characterization of oligonucleotides that inhibit Toll-like receptor 2-associated immune responses. FASEB J 2009; 23(9): 3078-88.
-
(2009)
FASEB J
, vol.23
, Issue.9
, pp. 3078-3088
-
-
Chang, Y.C.1
Kao, W.C.2
Wang, W.Y.3
Yang, R.B.4
Peck, K.5
-
242
-
-
34248515435
-
SELEX experiments: New prospects, applications and data analysis in inferring regulatory pathways
-
Djordjevic M. SELEX experiments: new prospects, applications and data analysis in inferring regulatory pathways. Biomol Eng 2007; 24(2): 179-89.
-
(2007)
Biomol Eng
, vol.24
, Issue.2
, pp. 179-189
-
-
Djordjevic, M.1
-
243
-
-
34447529270
-
Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes
-
Ledeboer A, Hutchinson MR, Watkins LR, Johnson KW. Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opin Investig Drugs 2007; 16(7): 935-50.
-
(2007)
Expert Opin Investig Drugs
, vol.16
, Issue.7
, pp. 935-950
-
-
Ledeboer, A.1
Hutchinson, M.R.2
Watkins, L.R.3
Johnson, K.W.4
-
244
-
-
73149087272
-
Ibudilast: A review of its pharmacology, efficacy and safety in respiratory and neurological disease
-
Rolan P, Hutchinson MR, Johnson KW. Ibudilast: a review of its pharmacology, efficacy and safety in respiratory and neurological disease. Exp Opun Pharmacother 2009; 10(17): 2897-904.
-
(2009)
Exp Opun Pharmacother
, vol.10
, Issue.17
, pp. 2897-2904
-
-
Rolan, P.1
Hutchinson, M.R.2
Johnson, K.W.3
-
245
-
-
77954102531
-
Digestive Disease Week. Turning Science into Medicine-part 2
-
Hodgkinson L. Digestive Disease Week. Turning Science into Medicine-part 2. Idrugs 2010; 13(7): 424-6.
-
(2010)
Idrugs
, vol.13
, Issue.7
, pp. 424-426
-
-
Hodgkinson, L.1
-
246
-
-
36849069342
-
Pivotal involvement of Fcgamma receptor IIA in the neutralization of lipopolysaccharide signaling via a potent novel anti-TLR4 monoclonal antibody 15C1
-
Dunn-Siegrist I, Leger O, Daubeuf B, et al. Pivotal involvement of Fcgamma receptor IIA in the neutralization of lipopolysaccharide signaling via a potent novel anti-TLR4 monoclonal antibody 15C1. J Biol Chem 2007; 282(48): 34817-27.
-
(2007)
J Biol Chem
, vol.282
, Issue.48
, pp. 34817-34827
-
-
Dunn-Siegrist, I.1
Leger, O.2
Daubeuf, B.3
-
247
-
-
67049095880
-
A novel toll-like receptor 4 (TLR4) antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis
-
Ungaro R, Fukata M, Hsu D, et al. A novel toll-like receptor 4 (TLR4) antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. Am J Physiol Gastrointest Liver Physiol 2009; 296(6): G1167-79.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
, Issue.6
, pp. G1167-G1179
-
-
Ungaro, R.1
Fukata, M.2
Hsu, D.3
-
248
-
-
81755178372
-
In vivo” Toll-like receptor 4 antagonism restores cardiac function during endotoxemia
-
Ehrentraut S, Lohner R, Schwederski M, et al. “In vivo” Toll-like receptor 4 antagonism restores cardiac function during endotoxemia. Shock 2011; 36(6): 613-20.
-
(2011)
Shock
, vol.36
, Issue.6
, pp. 613-620
-
-
Ehrentraut, S.1
Lohner, R.2
Schwederski, M.3
-
249
-
-
79957588414
-
receptor-4 antagonist eritoran tetrasodium for severe sepsis
-
Tidswell M, La Rosa SP. Toll-like receptor-4 antagonist eritoran tetrasodium for severe sepsis. Expert Rev Anti Infect Ther 2011; 9(5): 507-20.
-
(2011)
Expert Rev Anti Infect Ther
, vol.9
, Issue.5
, pp. 507-520
-
-
Tidswell, M.1
La Rosa, S.P.2
-
250
-
-
20044370433
-
Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production
-
Johnson BJ, Le TT, Dobbin CA, et al. Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production. J Biol Chem 2005; 280(6): 4037-47.
-
(2005)
J Biol Chem
, vol.280
, Issue.6
, pp. 4037-4047
-
-
Johnson, B.J.1
Le, T.T.2
Dobbin, C.A.3
-
251
-
-
79956188587
-
Toll-like receptor modulators: A patent review (2006-2010)
-
Basith S, Manavalan B, Lee G, Kim SG, Choi S. Toll-like receptor modulators: a patent review (2006-2010). Expert Opin Ther Pat 2011; 21(6): 927-44.
-
(2011)
Expert Opin Ther Pat
, vol.21
, Issue.6
, pp. 927-944
-
-
Basith, S.1
Manavalan, B.2
Lee, G.3
Kim, S.G.4
Choi, S.5
-
252
-
-
78651300299
-
TAK-242 (resatorvid): A small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules
-
Matsunaga N, Tsuchimori N, Matsumoto T, Ii M. TAK-242 (resatorvid): a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. Mol Pharmacol 2011; 79(1): 34-41.
-
(2011)
Mol Pharmacol
, vol.79
, Issue.1
, pp. 34-41
-
-
Matsunaga, N.1
Tsuchimori, N.2
Matsumoto, T.3
Ii, M.4
-
253
-
-
84860012585
-
Morphine activates neuroinflammation in a manner parallel to endotoxin
-
Wang X, Loram LC, Ramos K, et al. Morphine activates neuroinflammation in a manner parallel to endotoxin. Proc Natl Acad Sci USA 2012; 109(16): 6325-30.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.16
, pp. 6325-6330
-
-
Wang, X.1
Loram, L.C.2
Ramos, K.3
-
254
-
-
85038641906
-
IMS Lifecycle R&D Focus part of IMS LifeCycle
-
IMS Lifecycle R&D Focus part of IMS LifeCycle. Drug News 2009; 18(13): 34. Available from: http://www.tcl-pharma.com/1Tc LPharma/pdf/DrugNewsV18N13.pdf
-
(2009)
Drug News
, Issue.13
, pp. 18
-
-
-
255
-
-
44949147193
-
Acrolein with an alpha, beta-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4
-
Lee JS, Lee JY, Lee MY, Hwang DH, Youn HS. Acrolein with an alpha, beta-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4. Mol Cells 2008; 25(2): 253-7.
-
(2008)
Mol Cells
, vol.25
, Issue.2
, pp. 253-257
-
-
Lee, J.S.1
Lee, J.Y.2
Lee, M.Y.3
Hwang, D.H.4
Youn, H.S.5
-
256
-
-
84860218860
-
Curcumins promote monocytic gene expression related to β-amyloid and superoxide dismutase clearance
-
Cashman JR, Gagliardi S, Lanier M, et al. Curcumins promote monocytic gene expression related to β-amyloid and superoxide dismutase clearance. Neurodegener Dis 2012; 10(1-4): 274-6.
-
(2012)
Neurodegener Dis
, vol.10
, Issue.1-4
, pp. 274-276
-
-
Cashman, J.R.1
Gagliardi, S.2
Lanier, M.3
-
257
-
-
58349110928
-
The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse model of autoimmune disorders
-
Hultqvist M, Nandakumar KS, Björklund U, Holmdah R. The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse model of autoimmune disorders. Ann Rheum Dis 2009; 68(1): 130-5.
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.1
, pp. 130-135
-
-
Hultqvist, M.1
Nandakumar, K.S.2
Björklund, U.3
Holmdah, R.4
-
258
-
-
77955452602
-
Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells
-
Hultqvist M, Nandakumar KS, Bjorklund U, Holmdahl R. Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells. Ann Rheum Dis 2010; 69(8): 1527-32.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.8
, pp. 1527-1532
-
-
Hultqvist, M.1
Nandakumar, K.S.2
Bjorklund, U.3
Holmdahl, R.4
-
259
-
-
78649505991
-
The novel anti-rheumatic compound Rabeximod impairs differentiation and function of human pro-inflammatory dendritic cells and macrophages
-
Giusti P, Frascaroli G, Tammik C, et al. The novel anti-rheumatic compound Rabeximod impairs differentiation and function of human pro-inflammatory dendritic cells and macrophages. Immunobiology 2011; 216(1-2): 243-50.
-
(2011)
Immunobiology
, vol.216
, Issue.1-2
, pp. 243-250
-
-
Giusti, P.1
Frascaroli, G.2
Tammik, C.3
-
260
-
-
34249915031
-
Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus
-
Pawar RD, Ramanjaneyulu A, Kulkarni OP, et al. Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus. J Am Soc Nephrol 2007; 18(6): 1721-6.
-
(2007)
J Am Soc Nephrol
, vol.18
, Issue.6
, pp. 1721-1726
-
-
Pawar, R.D.1
Ramanjaneyulu, A.2
Kulkarni, O.P.3
-
261
-
-
17844383756
-
Inhibitors of TLR9 act on multiple cell subsets in mouse and man “in vitro” and prevent death “in vivo” from systemic inflammation
-
Duramad O, Fearon KL, Chang B, et al. Inhibitors of TLR9 act on multiple cell subsets in mouse and man “in vitro” and prevent death “in vivo” from systemic inflammation. J Immunol 2005; 174(9): 5193-200.
-
(2005)
J Immunol
, vol.174
, Issue.9
, pp. 5193-5200
-
-
Duramad, O.1
Fearon, K.L.2
Chang, B.3
-
262
-
-
33847049885
-
DNA motifs suppressing TLR9 responses
-
Trieu A, Roberts TL, Dunn JA, Sweet MJ, Stacey KJ. DNA motifs suppressing TLR9 responses. Clin Rev Immunol 2006; 26(6): 527- 44.
-
(2006)
Clin Rev Immunol
, vol.527-44
, Issue.6
, pp. 26
-
-
Trieu, A.1
Roberts, T.L.2
Dunn, J.A.3
Sweet, M.J.4
Stacey, K.J.5
-
263
-
-
26844467349
-
Nucleic acids of mammalian origin can act as EL for Toll-like receptors and may promote systemic lupus erythematosus
-
Barrat FJ, Meeker T, Gregorio J, et al. Nucleic acids of mammalian origin can act as EL for Toll-like receptors and may promote systemic lupus erythematosus. J Exp Med 2005; 202(8): 1131-9.
-
(2005)
J Exp Med
, vol.202
, Issue.8
, pp. 1131-1139
-
-
Barrat, F.J.1
Meeker, T.2
Gregorio, J.3
-
264
-
-
37549066665
-
Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms
-
Barrat FJ, Meeker T, Chan JH, Guiducci C, Coffman RL. Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms. Eur J Immunol 2007; 37(12): 3582-6.
-
(2007)
Eur J Immunol
, vol.37
, Issue.12
, pp. 3582-3586
-
-
Barrat, F.J.1
Meeker, T.2
Chan, J.H.3
Guiducci, C.4
Coffman, R.L.5
-
265
-
-
47249092785
-
Development of TLR inhibitors for the treatment of autoimmune diseases
-
Barrat FJ, Coffman RL. Development of TLR inhibitors for the treatment of autoimmune diseases. Immunol Rev 2008; 223: 271- 83.
-
(2008)
Immunol Rev
, vol.271-83
, pp. 223
-
-
Barrat, F.J.1
Coffman, R.L.2
-
266
-
-
80054952277
-
Safety and pharmacodynamics of IMO-3100; a novel Toll-like receptor antagonist for autoimmune and inflammatory diseases, in a rising single-dose phase I clinical trial
-
Sullivan T, Atiee G, Bhagat L, et al. Safety and pharmacodynamics of IMO-3100; a novel Toll-like receptor antagonist for autoimmune and inflammatory diseases, in a rising single-dose phase I clinical trial. Proceedings of the 6th Annual Meeting of the Oligonucleotide Therapeutic Society being held in Dana Point California, October 20-23: 2010.
-
(2010)
Proceedings of the 6th Annual Meeting of the Oligonucleotide Therapeutic Society being held in Dana Point California, October 20-23
-
-
Sullivan, T.1
Atiee, G.2
Bhagat, L.3
-
267
-
-
84878893173
-
Inflammatory proteins in plasma are associated with severity of Alzheimer’s disease
-
Leung R, Proitsi P, Simmons A, et al. Inflammatory proteins in plasma are associated with severity of Alzheimer’s disease. PLoS One 2013; 8 (6): e64971.
-
(2013)
PLoS One
, vol.8
, Issue.6
, pp. e64971
-
-
Leung, R.1
Proitsi, P.2
Simmons, A.3
-
268
-
-
70449429345
-
The development of nanobodies for therapeutic applications
-
Van Bockstaele F, Holz JB, Revets H. The development of nanobodies for therapeutic applications. Curr Opin Investig Drugs 2009; 10(11): 1212-24.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, Issue.11
, pp. 1212-1224
-
-
Van Bockstaele, F.1
Holz, J.B.2
Revets, H.3
-
269
-
-
84863810986
-
Targeting Toll-like Receptor (TLR) Signaling by Toll/Interleukin-1 Receptor (TIR) Domain-containing Adapter Protein/MyD88 Adapter-like (TIRAP/Mal)-derived Decoy Peptides
-
Couture LA, Piao W, Ru LW, Vogel SN, Toshchakov VY. Targeting Toll-like Receptor (TLR) Signaling by Toll/Interleukin-1 Receptor (TIR) Domain-containing Adapter Protein/MyD88 Adapter-like (TIRAP/Mal)-derived Decoy Peptides. J Biol Chem 2012; 287(29): 24641-8.
-
(2012)
J Biol Chem
, vol.287
, Issue.29
, pp. 24641-24648
-
-
Couture, L.A.1
Piao, W.2
Ru, L.W.3
Vogel, S.N.4
Toshchakov, V.Y.5
-
271
-
-
84863115420
-
Branched, tripartite-interfering RNAs silence multiple target genes with long guide strands
-
Chang CI, Lee TY, Yoo JW, et al. Branched, tripartite-interfering RNAs silence multiple target genes with long guide strands. Nucleic Acid Ther 2012; 22(1): 30-9.
-
(2012)
Nucleic Acid Ther
, vol.22
, Issue.1
, pp. 30-39
-
-
Chang, C.I.1
Lee, T.Y.2
Yoo, J.W.3
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