3D structure of Alzheimer's amyloid-β(1-42) fibrils

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 48, 2005, Pages 17342-17347

  Lührs, Thorsten ^a   Ritter, Christiane ^a   Adrian, Marc ^b   Riek Loher, Dominique ^a   Bohrmann, Bernd ^c   Döbeli, Heinz ^c   Schubert, David ^a   Riek, Roland ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Hydrogen deuterium exchange; NMR

Indexed keywords

AMYLOID BETA PROTEIN[1-42];

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; DEGENERATIVE DISEASE; DEUTERIUM HYDROGEN EXCHANGE; HYDROGEN BOND; MOLECULAR INTERACTION; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID; DEUTERIUM; HUMANS; HYDROGEN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION;

EID: 28444442999     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0506723102     Document Type: Article

References (33)

1. Selkoe, D. J. (2003) Nature 426, 900-904.
2. Tycko, R. (2004) Curr. Opin. Struct. Biol. 14, 96-103.
3. Ritter, C., Maddelein, M. L., Siemer, A. B., Luhrs, T., Ernst, M., Meier, B. H., Saupe, S. J. & Riek, R. (2005) Nature 435, 844-848.
4. Nelson, R., Sawaya, M. R., Balbirnie, M., Madsen, A. O., Riekel, C., Grothe, R. & Eisenberg, D. (2005) Nature 435, 773-778.
5. Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L. & Beyreuther, K. (1985) Proc. Natl. Acad. Sci. USA 82, 4245-4249.
6. Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K. & Muller-Hill, B. (1987) Nature 325, 733-736.
7. Jarrett, J. T., Berger, E. P. & Lansbury, P. T., Jr. (1993) Biochemistry 32, 4693-4697.
8. Burdick, D., Soreghan, B., Kwon, M., Kosmoski, J., Knauer, M., Henschen, A., Yates, J., Cotman, C. & Glabe, C. (1992) J. Biol. Chem. 267, 546-554.
9. Riek, R., Guntert, P., Dobeli, H., Wipf, B. & Wuthrich, K. (2001) Eur. J. Biochem. 268, 5930-5936.
10. Kirschner, D. A., Abraham, C. & Selkoe, D. J. (1986) Proc. Natl. Acad. Sci. USA 83, 503-507.
11. Balbach, J. J., Petkova, A. T., Oyler, N. A., Antzutkin, O. N., Gordon, D. J., Meredith, S. C. & Tycko, R. (2002) Biophys. J. 83, 1205-1216.
12. Alexandrescu, A. T. (2001) Pac. Symp. Biocomput., 67-78.
13. Hoshino, M., Katou, H., Hagihara, Y., Hasegawa, K., Naiki, H. & Goto, Y. (2002) Nat. Struct. Biol. 9, 332-336.
14. Kheterpal, I., Zhou, S., Cook, K. D. & Wetzel, R. (2000) Proc. Natl. Acad. Sci. USA 97, 13597-13601.
15. Wang, S. S., Tobler, S. A., Good, T. A. & Fernandez, E. J. (2003) Biochemistry 42, 9507-9514.
16. Torok, M., Milton, S., Kayed, R., Wu, P., McIntire, T., Glabe, C. G. & Langen, R. (2002) J. Biol. Chem. 277, 40810-40815.
17. Kheterpal, I., Williams, A., Murphy, C., Bledsoe, B. & Wetzel, R. (2001) Biochemistry 40, 11757-11767.
18. Egnaczyk, G. F., Greis, K. D., Stimson, E. R. & Maggio, J. E. (2001) Biochemistry 40, 11706-11714.
19. Petkova, A. T., Ishii, Y., Balbach, J. J., Antzutkin, O. N., Leapman, R. D., Delaglio, F. & Tycko, R. (2002) Proc. Natl. Acad. Sci. USA 99, 16742-16747.
20. Dobeli, H., Draeger, N., Huber, G., Jakob, P., Schmidt, D., Seilheimer, B., Stuber, D., Wipf, B. & Zulauf, M. (1995) Bio/Technology 13, 988-993.
21. Seilheimer, B., Bohrmann, B., Bondolfi, L., Muller, F., Stuber, D. & Dobeli, H. (1997) J. Struct. Biol. 119, 59-71.
22. Bohrmann, B., Adrian, M., Dubochet, J., Kuner, P., Muller, F., Huber, W., Nordstedt, C. & Dobeli, H. (2000) J. Struct. Biol. 130, 232-246.
23. LeVine, H., III (1999) Methods Enzymol. 309, 274-284.
24. Gordon, D. J., Sciarretta, K. L. & Meredith, S. C. (2001) Biochemistry 40, 8237-8245.
25. Wuthrich, K. (1986) NMR of Proteins and Nucleic Acids (Wiley, New York).
26. Koradi, R., Billeter, M. & Wuthrich, K. (1996) J. Mol. Graphics 14, 51-55.
27. Ban, T., Hoshino, M., Takahashi, S., Hamada, D., Hasegawa, K., Naiki, H. & Goto, Y. (2004) J. Mol. Biol. 344, 757-767.
28. Bieler, S. & Soto, C. (2004) Curr. Drug Targets 5, 553-558.
29. Behl, C., Davis, J. B., Lesley, R. & Schubert, D. (1994) Cell 77, 817-827.
30. Hardy, J. & Selkoe, D. J. (2002) Science 297, 353-356.
31. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., et al. (1998) Proc. Natl. Acad. Sci. USA 95, 6448-6453.
32. Hartley, D. M., Walsh, D. M., Ye, C. P., Diehl, T., Vasquez, S., Vassilev, P. M., Teplow, D. B. & Selkoe, D. J. (1999) J. Neurosci. 19, 8876-8884.
33. Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W. & Glabe, C. G. (2003) Science 300, 486-489.