mRNA Is an Endogenous Ligand for Toll-like Receptor 3

Journal of Biological Chemistry

Volumn 279, Issue 13, 2004, Pages 12542-12550

  Karikó, Katalin ^a   Ni, Houping ^a   Capodici, John ^a   Lamphier, Marc ^b   Weissman, Drew ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b EISAI RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; ENZYME KINETICS; IMMUNOLOGY; RNA; VIRUSES;

IMMUNE SYSTEMS; PATHOGENS;

BIOCHEMISTRY;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; LIGAND; LUCIFERASE; MESSENGER RNA; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNE SYSTEM; MESSENGER RNA SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; RNA REPLICATION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION;

BLOTTING, NORTHERN; CELL LINE; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENISTEIN; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-8; LIGANDS; LUCIFERASES; MEMBRANE GLYCOPROTEINS; NECROSIS; NF-KAPPA B; NUCLEIC ACID CONFORMATION; PLASMIDS; PROTEIN KINASES; RECEPTORS, CELL SURFACE; RNA; RNA, DOUBLE-STRANDED; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAUROSPORINE; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE; UP-REGULATION;

ANIMALIA;

EID: 1842477469     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310175200     Document Type: Article

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