Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 34, 2007, Pages 13798-13803

  Tang, Sung Chun ^a,b   Arumugam, Thiruma V ^a,c   Xu, Xiangru ^a   Cheng, Aiwu ^a   Mughal, Mohamed R ^a   Dong, Gyu Jo ^a,d   Lathia, Justin D ^a   Siler, Dominic A ^a   Chigurupati, Srinivasulu ^a   Ouyang, Xin ^a   Magnus, Tim ^a,f   Camandola, Simonetta ^a   Mattson, Mark P ^a,e  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^d Sungkyunkwan University   (South Korea)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF HAMBURG   (Germany)

Author keywords

AP 1; Apoptosis; Innate immunity; Ischemic stroke; Microglia

Indexed keywords

GLUCOSE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1; CASPASE 3; GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN INJURY; BRAIN ISCHEMIA; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; INNATE IMMUNITY; KNOCKOUT MOUSE; MICROARRAY ANALYSIS; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STROKE; TISSUE INJURY; ANIMAL; CEREBROVASCULAR ACCIDENT; DISEASE MODEL; DRUG EFFECT; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; TRANSGENIC MOUSE;

MUS;

ANIMALS; BRAIN ISCHEMIA; CASPASE 3; CELL DEATH; CEREBROVASCULAR ACCIDENT; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; INTERFERON TYPE II; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, TRANSGENIC; NEURONS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP-1;

EID: 35348860696     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0702553104     Document Type: Article

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