Acrolein with an α,β-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4

Molecules and Cells

Volumn 25, Issue 2, 2008, Pages 253-257

  Lee, Jeon Soo ^a   Lee, Joo Young ^b   Lee, Mi Young ^a   Hwang, Daniel H ^c   Youn, Hyung Sun ^a  

^a Soonchunhyang University   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acrolein; Dimerization; IRF3; LPS; Michael addition; NF B; Toll like receptor

Indexed keywords

ACROLEIN; CARBONYL DERIVATIVE; CIGARETTE SMOKE; CYSTEINE; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN DERIVATIVE; PROTEIN KINASE; TANK BINDING KINASE 1; THIOL GROUP; TIR DOMAIN CONTAINING ADAPTER INDUCING INTERFERON BETA; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DIMERIZATION; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFECTION; INFLAMMATION; MICHAEL ADDITION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

ACROLEIN; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL LINE; DIMERIZATION; HUMANS; INTERFERON REGULATORY FACTOR-3; LIPOPOLYSACCHARIDES; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; TOLL-LIKE RECEPTOR 4;

EID: 44949147193     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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