Purinergic regulation of inflammasome activation after central nervous system injury

Journal of General Physiology

Volumn 140, Issue 5, 2012, Pages 571-575

  Bernier, Louis Philippe ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GAP JUNCTION PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; NERVE PROTEIN; POTASSIUM; PURINERGIC RECEPTOR;

ANIMAL; CENTRAL NERVOUS SYSTEM; HUMAN; METABOLISM; NOTE; PATHOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CENTRAL NERVOUS SYSTEM; CONNEXINS; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; NERVE TISSUE PROTEINS; POTASSIUM; RECEPTORS, PURINERGIC;

EID: 84870839150     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.201210875     Document Type: Note

References (29)

1. Bao, L., S. Locovei, and G. Dahl. 2004. Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett. 572:65-68. http://dx.doi.org/10.1016/j.febslet.2004.07.009
2. Bernier, L.P., A.R. Ase, E. Boué-Grabot, and P. Séguéla. 2012. P2X4 receptor channels form large noncytolytic pores in resting and activated microglia. Glia. 60:728-737. http://dx.doi.org/10.1002/glia.22301
3. Burnstock, G. 2008. Purinergic signalling and disorders of the central nervous system. Nat. Rev. Drug Discov. 7:575-590. http://dx.doi.org/10.1038/nrd2605
4. Clark, A.K., A.A. Staniland, F. Marchand, T.K. Kaan, S.B. McMahon, and M. Malcangio. 2010. P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide. J. Neurosci. 30:573-582. http://dx.doi.org/10.1523/JNEUROSCI.3295-09.2010
5. de Rivero Vaccari, J.P., G. Lotocki, A.E. Marcillo, W.D. Dietrich, and R.W. Keane. 2008. A molecular platform in neurons regulates inflammation after spinal cord injury. J. Neurosci. 28:3404-3414. http://dx.doi.org/10.1523/JNEUROSCI.0157-08.2008
6. de Rivero Vaccari, J.P., G. Lotocki, O.F. Alonso, H.M. Bramlett, W.D. Dietrich, and R.W. Keane. 2009. Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury. J. Cereb. Blood Flow Metab. 29:1251-1261. http://dx.doi.org/10.1038/jcbfm.2009.46
7. de Rivero Vaccari, J.P., D. Bastien, G. Yurcisin, I. Pineau, W.D. Dietrich, Y. De Koninck, R.W. Keane, and S. Lacroix. 2012. P2X4 receptors influence inflammasome activation after spinal cord injury. J. Neurosci. 32:3058-3066. http://dx.doi.org/10.1523/JNEUROSCI.4930-11.2012
8. Di Virgilio, F. 2007. Liaisons dangereuses: P2X(7) and the inflammasome. Trends Pharmacol. Sci. 28:465-472. http://dx.doi.org/10.1016/j.tips.2007.07.002
9. Ferrari, D., P. Chiozzi, S. Falzoni, S. Hanau, and F. Di Virgilio. 1997. Purinergic modulation of interleukin-1 β release from microglial cells stimulated with bacterial endotoxin. J. Exp. Med. 185:579-582. http://dx.doi.org/10.1084/jem.185.3.579
10. Gross, O., C.J. Thomas, G. Guarda, and J. Tschopp. 2011. The inflammasome: an integrated view. Immunol. Rev. 243:136-151. http://dx.doi.org/10.1111/j.1600-065X.2011.01046.x
11. Huang, Y.J., Y. Maruyama, G. Dvoryanchikov, E. Pereira, N. Chaudhari, and S.D. Roper. 2007. The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc. Natl. Acad. Sci. USA. 104:6436-6441. http://dx.doi.org/10.1073/pnas.0611280104
12. Kukulski, F., S.A. Lévesque, and J. Sévigny. 2011. Impact of ectoenzymes on p2 and p1 receptor signaling. Adv. Pharmacol. 61:263-299. http://dx.doi.org/10.1016/B978-0-12-385526-8.00009-6
13. Nadeau, S., M. Filali, J. Zhang, B.J. Kerr, S. Rivest, D. Soulet, Y. Iwakura, J.P. de Rivero Vaccari, R.W. Keane, and S. Lacroix. 2011. Functional recovery after peripheral nerve injury is dependent on the pro-inflammatory cytokines IL-1β and TNF: implications for neuropathic pain. J. Neurosci. 31:12533-12542. http://dx.doi.org/10.1523/JNEUROSCI.2840-11.2011
14. North, R.A., and A. Surprenant. 2000. Pharmacology of cloned P2X receptors. Annu. Rev. Pharmacol. Toxicol. 40:563-580. http://dx.doi.org/10.1146/annurev.pharmtox.40.1.563
15. Ohsawa, K., Y. Irino, Y. Nakamura, C. Akazawa, K. Inoue, and S. Kohsaka. 2007. Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis. Glia. 55:604-616. http://dx.doi.org/10.1002/glia.20489
16. Pelegrin, P., and A. Surprenant. 2006. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J. 25:5071-5082. http://dx.doi.org/10.1038/sj.emboj.7601378
17. Pelegrin, P., C. Barroso-Gutierrez, and A. Surprenant. 2008. P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J. Immunol. 180:7147-7157.
18. Pétrilli, V., S. Papin, C. Dostert, A. Mayor, F. Martinon, and J. Tschopp. 2007. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14:1583-1589. http://dx.doi.org/10.1038/sj.cdd.4402195
19. Qu, Y., S. Misaghi, K. Newton, L.L. Gilmour, S. Louie, J.E. Cupp, G.R. Dubyak, D. Hackos, and V.M. Dixit. 2011. Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation. J. Immunol. 186:6553-6561. http://dx.doi.org/10.4049/jimmunol.1100478
20. Rice, T., J. Larsen, S. Rivest, and V.W. Yong. 2007. Characterization of the early neuroinflammation after spinal cord injury in mice. J. Neuropathol. Exp. Neurol. 66:184-195. http://dx.doi.org/10.1097/01.jnen.0000248552.07338.7f
21. Scholz, J., and C.J. Woolf. 2007. The neuropathic pain triad: neurons, immune cells and glia. Nat. Neurosci. 10:1361-1368. http://dx.doi.org/10.1038/nn1992
22. Schwab, J.M., L. Guo, and H.J. Schluesener. 2005. Spinal cord injury induces early and persistent lesional P2X4 receptor expression. J. Neuroimmunol. 163:185-189. http://dx.doi.org/10.1016/j.jneuroim.2005.02.016
23. Seil, M., M. El Ouaaliti, U. Fontanils, I.G. Etxebarria, S. Pochet, G. Dal Moro, A. Marino, and J.P. Dehaye. 2010. Ivermectindependent release of IL-1beta in response to ATP by peritoneal macrophages from P2X(7)-KO mice. Purinergic Signal. 6:405-416. http://dx.doi.org/10.1007/s11302-010-9205-8
24. Silverman, W.R., J.P. de Rivero Vaccari, S. Locovei, F. Qiu, S.K. Carlsson, E. Scemes, R.W. Keane, and G. Dahl. 2009. The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J. Biol. Chem. 284:18143-18151. http://dx.doi.org/10.1074/jbc.M109.004804
25. Tsuda, M., Y. Shigemoto-Mogami, S. Koizumi, A. Mizokoshi, S. Kohsaka, M.W. Salter, and K. Inoue. 2003. P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature. 424:778-783. http://dx.doi.org/10.1038/nature01786
26. Tsuda, M., H. Tozaki-Saitoh, and K. Inoue. 2010. Pain and purinergic signaling. Brain Res. Rev. 63:222-232. http://dx.doi.org/10.1016/j.brainresrev.2009.11.003
27. Ulmann, L., J.P. Hatcher, J.P. Hughes, S. Chaumont, P.J. Green, F. Conquet, G.N. Buell, A.J. Reeve, I.P. Chessell, and F. Rassendren. 2008. Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain. J. Neurosci. 28:11263-11268. http://dx.doi.org/10.1523/JNEUROSCI.2308-08.2008
28. Virginio, C., A. MacKenzie, R.A. North, and A. Surprenant. 1999. Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor. J. Physiol. 519:335-346. http://dx.doi.org/10.1111/j.1469-7793.1999.0335m.x
29. Xia, J., J.C. Lim, W. Lu, J.M. Beckel, E.J. Macarak, A.M. Laties, and C.H. Mitchell. 2012. Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors. J. Physiol. 590:2285-2304.