Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins

Biochemical Journal

Volumn 422, Issue 1, 2009, Pages 1-10

  Carpenter, Susan ^a   O'Neill, Luke A J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Innate immune system; Phosphorylation; Post translational modification; Signalling; Toll like receptor (TLR); Ubiquitination

Indexed keywords

INNATE IMMUNE SYSTEM; POST-TRANSLATIONAL MODIFICATION; SIGNALLING; TOLL-LIKE RECEPTOR (TLR); UBIQUITINATION;

IMMUNOLOGY; PHOSPHORYLATION; POLYSACCHARIDES; TUMORS;

INTERFERONS;

ADAPTOR PROTEIN; BACTERIUM LIPOPOLYSACCHARIDE; DOUBLE STRANDED RNA; I KAPPA B KINASE GAMMA; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; LYSINE; PELLINO; PROTEIN A20; PROTEIN MD 2; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; TWO RING FINGERS AND DOUBLE RING FINGER LINKED 3A; TYROSINE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; HUMAN; IMMUNOMODULATION; INNATE IMMUNITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; HUMANS; LIGANDS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 68749115366     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090616     Document Type: Review

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