-
1
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass CK, Saijo K, Winner B, et al. Mechanisms underlying inflammation in neurodegeneration. Cell 2010;140:918-34
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
-
2
-
-
77950365906
-
Nonresolving inflammation
-
Nathan C, Ding A. Nonresolving inflammation. Cell 2010;140:871-82
-
(2010)
Cell
, vol.140
, pp. 871-882
-
-
Nathan, C.1
Ding, A.2
-
3
-
-
47749126515
-
Why neurodegenerative diseases are progressive: Uncontrolled inflammation drives disease progression
-
Gao H-M, Hong J-S. Why neurodegenerative diseases are progressive: Uncontrolled inflammation drives disease progression. Trends Immunol 2008;29:357-65
-
(2008)
Trends Immunol
, vol.29
, pp. 357-365
-
-
Gao, H.-M.1
Hong, J.-S.2
-
4
-
-
33748743268
-
CNS immune privilege: Hiding in plain sight
-
Carson MJ, Doose JM, Melchior B, et al. CNS immune privilege: Hiding in plain sight. Immunol Rev 2006;213:48-65
-
(2006)
Immunol Rev
, vol.213
, pp. 48-65
-
-
Carson, M.J.1
Doose, J.M.2
Melchior, B.3
-
7
-
-
66449130960
-
Regulation of innate immune responses in the brain
-
Rivest S. Regulation of innate immune responses in the brain. Nat Rev Immunol 2009;9:429-39
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 429-439
-
-
Rivest, S.1
-
8
-
-
72449204160
-
Does neuroinflammation fan the flame in neurodegenerative diseases?
-
Frank-Cannon T, Alto L, McAlpine F, et al. Does neuroinflammation fan the flame in neurodegenerative diseases? Mol Neurodegener 2009;4:47
-
(2009)
Mol Neurodegener
, vol.4
, pp. 47
-
-
Frank-Cannon, T.1
Alto, L.2
McAlpine, F.3
-
9
-
-
70349795301
-
Harnessing immune alterations in neurodegenerative diseases
-
Bjorkqvist M, Wild EJ, Tabriz SJ. Harnessing immune alterations in neurodegenerative diseases. Neuron 2009;64:21-4
-
(2009)
Neuron
, vol.64
, pp. 21-24
-
-
Bjorkqvist, M.1
Wild, E.J.2
Tabriz, S.J.3
-
10
-
-
73949090103
-
Inflammation in neurodegenerative diseases
-
Amor S, Puentes F, Baker D, et al. Inflammation in neurodegenerative diseases. Immunol 2010;154-69
-
(2010)
Immunol
, pp. 154-169
-
-
Amor, S.1
Puentes, F.2
Baker, D.3
-
11
-
-
0035170589
-
T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: Involvement of metalloproteinases
-
Newman TA, Woolley ST, Hughes PM, et al. T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: involvement of metalloproteinases. Brain 2001;124:2203-14
-
(2001)
Brain
, vol.124
, pp. 2203-2214
-
-
Newman, T.A.1
Woolley, S.T.2
Hughes, P.M.3
-
12
-
-
0037530542
-
Vulnerability of human neurons to T cell mediated cytotoxicity
-
Giuliani F, Goodyer CG, Antel JP, et al. Vulnerability of human neurons to T cell mediated cytotoxicity. J. Immunol 2003;171:368-79
-
(2003)
J. Immunol
, vol.171
, pp. 368-379
-
-
Giuliani, F.1
Goodyer, C.G.2
Antel, J.P.3
-
13
-
-
33747890559
-
The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases
-
Zipp F, Aktas O. The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci 2006;29:518-27
-
(2006)
Trends Neurosci
, vol.29
, pp. 518-527
-
-
Zipp, F.1
Aktas, O.2
-
14
-
-
64249134817
-
CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis
-
Wolf SA, Steiner B, Akpinarli A, et al. CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis. J Immunol 2009;182:3979-84
-
(2009)
J Immunol
, vol.182
, pp. 3979-3984
-
-
Wolf, S.A.1
Steiner, B.2
Akpinarli, A.3
-
15
-
-
79957881476
-
Brain homeostasis is maintained by ''danger'' signals stimulating a supportive immune response within brain's borders
-
Ron-Harel N, Cardon M, Schwartz M. Brain homeostasis is maintained by ''danger'' signals stimulating a supportive immune response within brain's borders. Brain Behav Immun 2010;25:1036-43
-
(2010)
Brain Behav Immun
, vol.25
, pp. 1036-1043
-
-
Ron-Harel, N.1
Cardon, M.2
Schwartz, M.3
-
16
-
-
43949114888
-
Can the immune subsystem be harnessed to repair the CNS
-
Popovich PC, Longbrake EE. Can the immune subsystem be harnessed to repair the CNS. Nature Rev Neurosci 2008;9:481-93
-
(2008)
Nature Rev Neurosci
, vol.9
, pp. 481-493
-
-
Popovich, P.C.1
Longbrake, E.E.2
-
17
-
-
55749110043
-
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
-
Beers DR, Henkel JS, Zhao W, et al. CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc Natl Acad Sci USA 2008;105:15558-6
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15558-15566
-
-
Beers, D.R.1
Henkel, J.S.2
Zhao, W.3
-
18
-
-
0029972857
-
Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function
-
Elkabes S, DiCicco-loom EM, Black IB. Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function. J Neurosci 1996;16:2508-21
-
(1996)
J Neurosci
, vol.16
, pp. 2508-2521
-
-
Elkabes, S.1
DiCicco-loom, E.M.2
Black, I.B.3
-
19
-
-
0036845819
-
Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: Implications for multiple sclerosis therapy
-
Ziemssen T, Kumpfel T, Klinkert WEF, et al. Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain 2002;125:2381-91
-
(2002)
Brain
, vol.125
, pp. 2381-2391
-
-
Ziemssen, T.1
Kumpfel, T.2
Klinkert, W.E.F.3
-
21
-
-
80053289163
-
Toll-like receptors are key players in neurodegeneration
-
Arroyo DS, Soria JA, Gaviglio EA, et al. Toll-like receptors are key players in neurodegeneration. Int Immunopharmacol 2011;1:1415-21
-
(2011)
Int Immunopharmacol
, vol.1
, pp. 1415-1421
-
-
Arroyo, D.S.1
Soria, J.A.2
Gaviglio, E.A.3
-
22
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors. Nat Immunol 2010;11:373-84
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
23
-
-
30044442866
-
How Toll-like receptors signal: What we know and what we don't know
-
O'Neill LA. How Toll-like receptors signal: what we know and what we don't know. Curr Opin Immunol 2006;18:3-9
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 3-9
-
-
O'Neill, L.A.1
-
24
-
-
33748696772
-
The role of Toll-like receptors in CNS response to microbial challenge
-
Konat GW, Kielian T, Marriott I. The role of Toll-like receptors in CNS response to microbial challenge. J Neurochem 2006;99:1-12
-
(2006)
J Neurochem
, vol.99
, pp. 1-12
-
-
Konat, G.W.1
Kielian, T.2
Marriott, I.3
-
25
-
-
4644232615
-
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
-
Olson JK, Miller SD. Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol 2004;173:3916-24
-
(2004)
J Immunol
, vol.173
, pp. 3916-3924
-
-
Olson, J.K.1
Miller, S.D.2
-
26
-
-
80052513039
-
TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNS
-
Butchi NB, Woods T, Du M, et al. TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNS. Am J Pathol 2011;179:783-94
-
(2011)
Am J Pathol
, vol.179
, pp. 783-794
-
-
Butchi, N.B.1
Woods, T.2
Du, M.3
-
27
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005;308:1314-18
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
28
-
-
0036847816
-
Microglia as neuroprotective, immunocompetent cells of the CNS
-
Streit WL. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 2002;40:133-9
-
(2002)
Glia
, vol.40
, pp. 133-139
-
-
Streit, W.L.1
-
29
-
-
32344440522
-
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
-
Simard AR, Soulet D, Gowing G, et al. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 2006;49:489-502
-
(2006)
Neuron
, vol.49
, pp. 489-502
-
-
Simard, A.R.1
Soulet, D.2
Gowing, G.3
-
30
-
-
33748447845
-
Microglia, major player in the brain inflammation: Their role in the pathogenesis of Parkinson's disease
-
Kim YS, Joh TH. Microglia, major player in the brain inflammation: Their role in the pathogenesis of Parkinson's disease. Exp Mol Med 2006;38:333-47
-
(2006)
Exp Mol Med
, vol.38
, pp. 333-347
-
-
Kim, Y.S.1
Joh, T.H.2
-
31
-
-
24144453087
-
Microglia and inflammation mediated neurodegeneration: Multiple triggers with a common mechanism
-
Block ML, Hong JS. Microglia and inflammation mediated neurodegeneration: Multiple triggers with a common mechanism. Prog Neurobiol 2005;76:77-9
-
(2005)
Prog Neurobiol
, vol.76
, pp. 77-79
-
-
Block, M.L.1
Hong, J.S.2
-
32
-
-
0029883129
-
A femtomolar-acting neuroprotective peptide
-
Brenneman DE, Gozes I. A femtomolar-acting neuroprotective peptide. J Clin Invest 1996;97:2299-307
-
(1996)
J Clin Invest
, vol.97
, pp. 2299-2307
-
-
Brenneman, D.E.1
Gozes, I.2
-
33
-
-
14244264502
-
Prevention of Alzheimer's disease pathology by cannabinoids: Neuroprotection mediated by blockade of microglial activation
-
Ramirez BG, Blazquez C, Gomez del Pulgar T, et al. Prevention of Alzheimer's disease pathology by cannabinoids: Neuroprotection mediated by blockade of microglial activation. J Neurosci 2005;25:190-1913
-
(2005)
J Neurosci
, vol.25
, pp. 190-1913
-
-
Ramirez, B.G.1
Blazquez, C.2
Gomez Del Pulgar, T.3
-
34
-
-
73149113054
-
Anandamide enhances IL-10 production in activated microglia by targeting CB (2) receptors; roles of ERK1/2, JNK and NF-kappaB
-
Correa F, Hernangomez M, Mestre L, et al. Anandamide enhances IL-10 production in activated microglia by targeting CB (2) receptors; roles of ERK1/2, JNK and NF-kappaB. Glia 2010;58:135-47
-
(2010)
Glia
, vol.58
, pp. 135-147
-
-
Correa, F.1
Hernangomez, M.2
Mestre, L.3
-
35
-
-
33744832035
-
TGFbeta1 regulates the inflammatory response during chronic neurodegeneration
-
Boche D, Cunningham C, Docagne F, et al. TGFbeta1 regulates the inflammatory response during chronic neurodegeneration. Neurobiol Dis 2006;22:638-50
-
(2006)
Neurobiol Dis
, vol.22
, pp. 638-650
-
-
Boche, D.1
Cunningham, C.2
Docagne, F.3
-
36
-
-
0033944415
-
Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14 - prostaglandin J2 in the regulation of microglial functions
-
Bernardo A, Levi G, Minghetti L. Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14 - prostaglandin J2 in the regulation of microglial functions. Eur J Neurosci 2000;12:2215-23
-
(2000)
Eur J Neurosci
, vol.12
, pp. 2215-2223
-
-
Bernardo, A.1
Levi, G.2
Minghetti, L.3
-
37
-
-
33745573660
-
Control of microglial neurotoxicity by the fractalkine receptor
-
Cardona AE, Pioro EP, Sasse ME, et al. Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci 2006;9:917-24
-
(2006)
Nat Neurosci
, vol.9
, pp. 917-924
-
-
Cardona, A.E.1
Pioro, E.P.2
Sasse, M.E.3
-
38
-
-
20844449561
-
Role of fractalkine (CX3CL1) in regulating neuron-microglia interactions: Development of viral-based CX3CR1 antagonists
-
Streit WJ, Davis CN, Harrison JK. Role of fractalkine (CX3CL1) in regulating neuron-microglia interactions: development of viral-based CX3CR1 antagonists. Curr Alzheimer Res 2005;2:187-9
-
(2005)
Curr Alzheimer Res
, vol.2
, pp. 187-189
-
-
Streit, W.J.1
Davis, C.N.2
Harrison, J.K.3
-
39
-
-
0035278914
-
Cytokines and the central nervous system
-
Szelenyi J. Cytokines and the central nervous system. Brain Res Bull 2001;54:329-38
-
(2001)
Brain Res Bull
, vol.54
, pp. 329-338
-
-
Szelenyi, J.1
-
40
-
-
0030043899
-
Immune-neuro-endocrine interactions: Facts and hypotheses
-
Besedovsky HO, del Rey A. Immune-neuro-endocrine interactions: facts and hypotheses. Endocr. Rev 1996;17:64-102
-
(1996)
Endocr. Rev
, vol.17
, pp. 64-102
-
-
Besedovsky, H.O.1
Del Rey, A.2
-
41
-
-
84891744930
-
Harnessing a neural-immune circuit to control inflammation and shock
-
Blalock JE. Harnessing a neural-immune circuit to control inflammation and shock. J Exp Med 2002;18:195-F25-8
-
(2002)
J Exp Med
, vol.18
-
-
Blalock, J.E.1
-
42
-
-
0031938317
-
The proinflammatory cytokine network: Interactions in the CNS and blood of rhesus monkeys
-
Reyes TM, Coe CL. The proinflammatory cytokine network: interactions in the CNS and blood of rhesus monkeys. Am J Physiol 1998;274:R139-44
-
(1998)
Am J Physiol
, vol.274
-
-
Reyes, T.M.1
Coe, C.L.2
-
43
-
-
57449118499
-
Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide
-
Konsman JP, Veeneman J, Combe C, et al. Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide. Eur J Neurosci 2008;28:2499-510
-
(2008)
Eur J Neurosci
, vol.28
, pp. 2499-2510
-
-
Konsman, J.P.1
Veeneman, J.2
Combe, C.3
-
44
-
-
0026334912
-
Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism
-
Banks WA, Ortiz L, Plotkin SR, et al. Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism. J Pharmacol Exp Ther 1991;259:988-96
-
(1991)
J Pharmacol Exp Ther
, vol.259
, pp. 988-996
-
-
Banks, W.A.1
Ortiz, L.2
Plotkin, S.R.3
-
45
-
-
0032521331
-
Vagotomy blocks the induction of interleukin-1beta (IL-1beta) mRNA in the brain of rats in response to systemic IL-1beta
-
Hansen MK, Taishi P, Chen Z, et al. Vagotomy blocks the induction of interleukin-1beta (IL-1beta) mRNA in the brain of rats in response to systemic IL-1beta. J. Neurosci 1998;18:2247-53
-
(1998)
J. Neurosci
, vol.18
, pp. 2247-2253
-
-
Hansen, M.K.1
Taishi, P.2
Chen, Z.3
-
48
-
-
70350337098
-
Dual functionality of interleukin-1 family cytokines: Implications for anti-interleukin-1 therapy
-
Luheshi NM, Rothwell NJ, Brough D. Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy. Br J Pharmacol 2009;157:1318-29
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1318-1329
-
-
Luheshi, N.M.1
Rothwell, N.J.2
Brough, D.3
-
49
-
-
77950140276
-
Caspase inhibition by cardiotrophin-1 prevents neuronal death in vivo and in vitro
-
Peng H, Sola A, Moore J, et al. Caspase inhibition by cardiotrophin-1 prevents neuronal death in vivo and in vitro. J Neurosci Res 2010;88:1041-51
-
(2010)
J Neurosci Res
, vol.88
, pp. 1041-1051
-
-
Peng, H.1
Sola, A.2
Moore, J.3
-
50
-
-
45449113531
-
Inhibition of NMDA-induced outward currents by interleukin-1beta in hippocampal neurons
-
Zhang R, Yamada J, Hayashi Y, et al. Inhibition of NMDA-induced outward currents by interleukin-1beta in hippocampal neurons. Biochem Biophys Res Commun 2008;372:816-20
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 816-820
-
-
Zhang, R.1
Yamada, J.2
Hayashi, Y.3
-
51
-
-
7244251521
-
Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1expression in the brain
-
Ferrari CC, Depino AM, Prada F, et al. Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1expression in the brain. Am J Pathol 2004;165:1827-37
-
(2004)
Am J Pathol
, vol.165
, pp. 1827-1837
-
-
Ferrari, C.C.1
Depino, A.M.2
Prada, F.3
-
52
-
-
79956137679
-
Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin
-
Vaz AR, Silva SL, Barateiro A, et al. Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin. Exp Neurol 2011;229:381-90
-
(2011)
Exp Neurol
, vol.229
, pp. 381-390
-
-
Vaz, A.R.1
Silva, S.L.2
Barateiro, A.3
-
54
-
-
0036518997
-
Innate immunity: The missing link in neuroprotection and neurodegeneration?
-
Nguyen MD, Julien JP, Rivest S. Innate immunity: The missing link in neuroprotection and neurodegeneration? Nat Rev Neurosci 2002;3:216-27
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 216-227
-
-
Nguyen, M.D.1
Julien, J.P.2
Rivest, S.3
-
55
-
-
79957921767
-
IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection
-
Xin J, Wainwright DA, Mesnard NA, et al. IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection. Brain Beh Immunit 2011;25:820-9
-
(2011)
Brain Beh Immunit
, vol.25
, pp. 820-829
-
-
Xin, J.1
Wainwright, D.A.2
Mesnard, N.A.3
-
56
-
-
68949212050
-
Interleukin-10 provides direct trophic support to neurons
-
Zhou Z, Peng X, Insolera R, et al. Interleukin-10 provides direct trophic support to neurons. J Neurochem 2009;110:1617-27
-
(2009)
J Neurochem
, vol.110
, pp. 1617-1627
-
-
Zhou, Z.1
Peng, X.2
Insolera, R.3
-
57
-
-
23844524089
-
Intracellular protein therapy with SOCS-3 inhibits inflammation and apoptosis
-
Jo D, Liu D, Yao S, et al. Intracellular protein therapy with SOCS-3 inhibits inflammation and apoptosis. Nat Med 2005;11:892-8
-
(2005)
Nat Med
, vol.11
, pp. 892-898
-
-
Jo, D.1
Liu, D.2
Yao, S.3
-
58
-
-
66149103723
-
Cholinergic control of inflammation
-
Rosas-Ballina M, Tracey KJ. Cholinergic control of inflammation. J Int Med 2009;265:663-79
-
(2009)
J Int Med
, vol.265
, pp. 663-66679
-
-
Rosas-Ballina, M.1
Tracey, K.J.2
-
59
-
-
0034713266
-
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
-
Borovikova LV, Ivanova S, Zhang M, et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 2000;405:458-62
-
(2000)
Nature
, vol.405
, pp. 458-462
-
-
Borovikova, L.V.1
Ivanova, S.2
Zhang, M.3
-
60
-
-
0037128663
-
Pharmacological stimulation of the cholinergic antiinflammatory pathway
-
Bernik TR, Friedman SG, Ochani M, et al. Pharmacological stimulation of the cholinergic antiinflammatory pathway. J Exp Med 2002;195:781-8
-
(2002)
J Exp Med
, vol.195
, pp. 781-788
-
-
Bernik, T.R.1
Friedman, S.G.2
Ochani, M.3
-
61
-
-
0037461768
-
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
-
Wang H, Yu M, Ochani M, et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 2003;421:384-8
-
(2003)
Nature
, vol.421
, pp. 384-388
-
-
Wang, H.1
Yu, M.2
Ochani, M.3
-
62
-
-
79955008177
-
Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site
-
Gill JK, Savolainen M, Young GT, et al. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci USA 2011a;108:5867-72
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 5867-5872
-
-
Gill, J.K.1
Savolainen, M.2
Young, G.T.3
-
63
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J Mol Biol 2005;346:967-89
-
(2005)
J Mol Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
64
-
-
34548677767
-
Allosteric modulation of nicotinic acetylcholine receptors
-
Bertrand D, Gopalakrishnan M. Allosteric modulation of nicotinic acetylcholine receptors. Biochem Pharmacol 2007;74:1155-63
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1155-1163
-
-
Bertrand, D.1
Gopalakrishnan, M.2
-
65
-
-
79955008177
-
Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site
-
Gill JK, Savolainen M, Young GT, et al. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci USA 2011b;108:5867-72
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 5867-5872
-
-
Gill, J.K.1
Savolainen, M.2
Young, G.T.3
-
66
-
-
55849118078
-
Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor
-
Waldburger JM, Boyle Dl, Pavlov VA, et al. Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor. Arthritis Rheum 2008;58:3439-49
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3439-3449
-
-
Waldburger, J.M.1
Boyle, D.L.2
Pavlov, V.A.3
-
67
-
-
80053593864
-
Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit
-
Rosa-Ballina M, Olofsson PS, Ochani M, et al. Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science 2011;334:98-101
-
(2011)
Science
, Issue.334
, pp. 98-101
-
-
Rosa-Ballina, M.1
Olofsson, P.S.2
Ochani, M.3
-
68
-
-
77954215043
-
Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats
-
Loram LC, Harrison JA, Chao L, et al. Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats. Brain Behav Immun 2010;24:959-67
-
(2010)
Brain Behav Immun
, vol.24
, pp. 959-967
-
-
Loram, L.C.1
Harrison, J.A.2
Chao, L.3
-
69
-
-
77349114869
-
Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain
-
Gao BX, Hierl M, Clarkin K, et al. Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain. Pain 2010;149:33-49
-
(2010)
Pain
, vol.149
, pp. 33-49
-
-
Gao, B.X.1
Hierl, M.2
Clarkin, K.3
-
70
-
-
70350617803
-
A randomized double-blind, placebo controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain
-
Rowbotham MC, Duan WR, Thomas J, et al. A randomized double-blind, placebo controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain. Pain 2009;146:245-52
-
(2009)
Pain
, vol.146
, pp. 245-252
-
-
Rowbotham, M.C.1
Duan, W.R.2
Thomas, J.3
-
71
-
-
40149104224
-
alpha7 nicotinic acetylcholine receptor: A link between inflammation and neurodegeneration
-
Conejero-Goldberg C, Davies P. Ulloa l. alpha7 nicotinic acetylcholine receptor: A link between inflammation and neurodegeneration. Neurosci Biobehav Rev 2008;32:693-706
-
(2008)
Neurosci Biobehav Rev
, vol.32
, pp. 693-706
-
-
Conejero-Goldberg, C.1
Davies, P.2
Ulloa, L.3
-
72
-
-
0035120525
-
Evidence that neurons accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease
-
D'Andrea MR, Nagelke RG, Wang HY, et al. Evidence that neurons accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease. Histopathology 2001;38:120-34
-
(2001)
Histopathology
, vol.38
, pp. 120-134
-
-
D'Andrea, M.R.1
Nagelke, R.G.2
Wang, H.Y.3
-
73
-
-
0035251677
-
Nicotinic receptor abnormalities of Alzheimer's disease: Therapeutic implications
-
Nordberg A. Nicotinic receptor abnormalities of Alzheimer's disease: Therapeutic implications. Biol Psychiatry 2001;49:200-10
-
(2001)
Biol Psychiatry
, vol.49
, pp. 200-210
-
-
Nordberg, A.1
-
74
-
-
33744920090
-
Microglail alpha7 nicotinic acetylcholine receptors drive a phospholipase C/ IP3 pathway and modulate the cell activation toward a neuroprotective role
-
Suzuki T, Hide I, Matsubara A, et al. Microglail alpha7 nicotinic acetylcholine receptors drive a phospholipase C/ IP3 pathway and modulate the cell activation toward a neuroprotective role. J Neurosci Res 2006;83:1461-70
-
(2006)
J Neurosci Res
, vol.83
, pp. 1461-1470
-
-
Suzuki, T.1
Hide, I.2
Matsubara, A.3
-
75
-
-
13844275561
-
Relationship between alpha 7nAChR and apoptosis in human lymphocytes
-
DeRosa MJ, Esandi MC, Garelli A, et al. Relationship between alpha 7nAChR and apoptosis in human lymphocytes. J Neuroimmunol 2005;160:154-61
-
(2005)
J Neuroimmunol
, vol.160
, pp. 154-161
-
-
DeRosa, M.J.1
Esandi, M.C.2
Garelli, A.3
-
76
-
-
17844410317
-
Microglial activation in chronic neurodegenerative diseases: Roles of apoptotic neurons and chronic stimulation
-
Menghetti L, Ajmone-Cat MA, De Berardinis MA, et al. Microglial activation in chronic neurodegenerative diseases: Roles of apoptotic neurons and chronic stimulation. Brain Res Brain Res Rev 2005;48:251-6
-
(2005)
Brain Res Brain Res Rev
, vol.48
, pp. 251-256
-
-
Menghetti, L.1
Ajmone-Cat, M.A.2
De Berardinis, M.A.3
-
77
-
-
34547558959
-
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation
-
de Jonge WJ, Ulloa L. The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation. Br J Pharmacol 2007;151:915-29
-
(2007)
Br J Pharmacol
, vol.151
, pp. 915-929
-
-
De Jonge, W.J.1
Ulloa, L.2
-
78
-
-
0017353911
-
Biochemical characterization of a serum thymic hormone
-
Bach JF, Dardenne M, Pleau JM, et al. Biochemical characterization of a serum thymic hormone. Nature 1977;266:55-6
-
(1977)
Nature
, vol.266
, pp. 55-56
-
-
Bach, J.F.1
Dardenne, M.2
Pleau, J.M.3
-
80
-
-
0034027511
-
The role of cytokines and prostaglandin-E2 in thymulin induced hyperalgesia
-
Safieh-Garabedian B, Dardenne M, Kanaan SA, et al. The role of cytokines and prostaglandin-E2 in thymulin induced hyperalgesia. Neuropharmacol 2000;39:1653-61
-
(2000)
Neuropharmacol
, vol.39
, pp. 1653-1661
-
-
Safieh-Garabedian, B.1
Dardenne, M.2
Kanaan, S.A.3
-
81
-
-
0029882778
-
Thymulin reduces hyperalgesia induced by peripheral endotoxin injection in rats and mice
-
Safieh-Garabedian B, Jalakhian RH, Saade NE, et al. Thymulin reduces hyperalgesia induced by peripheral endotoxin injection in rats and mice. Brain Res 1996;717:179-83
-
(1996)
Brain Res
, vol.717
, pp. 179-183
-
-
Safieh-Garabedian, B.1
Jalakhian, R.H.2
Saade, N.E.3
-
82
-
-
50449087582
-
Thymulin inhibits monocrotaline-induced pulmonary hypertension modulating interleukin-6 expression and suppressing p38 pathway
-
Henriques-Coelho T, Oliveira SM, Moura RS, et al. Thymulin Inhibits Monocrotaline-Induced Pulmonary Hypertension Modulating Interleukin-6 Expression and Suppressing p38 Pathway. Endocrinology 2008;149:4367-73
-
(2008)
Endocrinology
, vol.149
, pp. 4367-4373
-
-
Henriques-Coelho, T.1
Oliveira, S.M.2
Moura, R.S.3
-
84
-
-
0018597211
-
Antagonistic analogue of serum thymic factor (FTS) interacting with FTS cellular receptor
-
Pleau JM, Dardenne M, Blanot D, et al. Antagonistic analogue of serum thymic factor (FTS) interacting with FTS cellular receptor. Immunol Lett 1979;1:179-82
-
(1979)
Immunol Lett
, vol.1
, pp. 179-182
-
-
Pleau, J.M.1
Dardenne, M.2
Blanot, D.3
-
85
-
-
0036022638
-
Potent analgesic and anti-inflammatory actions of a novel thymulin-related peptide in the rat
-
Safieh-Garabedian B, Dardenne M, Pleau JM, et al. Potent analgesic and anti-inflammatory actions of a novel thymulin-related peptide in the rat. Br J Pharmacol 2002;136:947-55
-
(2002)
Br J Pharmacol
, vol.136
, pp. 947-955
-
-
Safieh-Garabedian, B.1
Dardenne, M.2
Pleau, J.M.3
-
86
-
-
0037649980
-
A thymulin analogue peptide with powerful inhibitory effects on pain of neurogenic origin
-
Saade NE, Atweh SF, Jabbur SJ, et al. A thymulin analogue peptide with powerful inhibitory effects on pain of neurogenic origin. Neurosci 2003;119:155-65
-
(2003)
Neurosci
, vol.119
, pp. 155-165
-
-
Saade, N.E.1
Atweh, S.F.2
Jabbur, S.J.3
-
87
-
-
0142247469
-
Thymulin reverses inflammatory hyperalgesia and modulates the increased concentration of proinflammatory cytokines induced by i. cv. endotoxin injection
-
Safieh-Garabedian B, Ochoa-Chaar CI, Poole S, et al. Thymulin reverses inflammatory hyperalgesia and modulates the increased concentration of proinflammatory cytokines induced by i. c.v. endotoxin injection. Neurosci 2003;121:865-73
-
(2003)
Neurosci
, vol.121
, pp. 865-873
-
-
Safieh-Garabedian, B.1
Ochoa-Chaar, C.I.2
Poole, S.3
-
88
-
-
78650834290
-
Thymulin related peptide attenuates inflammation in the brain induced by intracerebroventricular endotoxin injection
-
Safieh-Garabedian B, Jabbur SJ, Dardenne M, et al. Thymulin related peptide attenuates inflammation in the brain induced by intracerebroventricular endotoxin injection. Neuropharmacol 2011;60:496-504
-
(2011)
Neuropharmacol
, Issue.60
, pp. 496-504
-
-
Safieh-Garabedian, B.1
Jabbur, S.J.2
Dardenne, M.3
-
90
-
-
84891739852
-
Inhibition of local inflammation and hyperalgesia by the peptide analogue to thymulin (PAT) is partially mediated by cholinergic mechanisms
-
Milano
-
Safieh-Garabedian B, Mardam Bey R, Barchini J, et al. Inhibition of local inflammation and hyperalgesia by the peptide analogue to thymulin (PAT) is partially mediated by cholinergic mechanisms. IASP Meeting; Milano; 2012
-
(2012)
IASP Meeting
-
-
Safieh-Garabedian, B.1
Mardam Bey, R.2
Barchini, J.3
-
91
-
-
33847759064
-
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
-
Qin L, Wu X, Block ML, et al. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia 2007;55:453-62
-
(2007)
Glia
, vol.55
, pp. 453-462
-
-
Qin, L.1
Wu, X.2
Block, M.L.3
-
92
-
-
79851514470
-
Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: Effects on brain cytokines and neurotrophins
-
Al-Amin H, Sarkis R, Atweh S, et al. Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: Effects on brain cytokines and neurotrophins. Exp Neurol 2011;228:30-40
-
(2011)
Exp Neurol
, vol.228
, pp. 30-40
-
-
Al-Amin, H.1
Sarkis, R.2
Atweh, S.3
-
95
-
-
0035135369
-
Activation of murine microglial cell lines by lipopolysaccharide and interferon-g causes NO-mediated decreases in mitochondrial and cellular function
-
Moss DW, Bates TE. Activation of murine microglial cell lines by lipopolysaccharide and interferon-g causes NO-mediated decreases in mitochondrial and cellular function. Eur J Neurosci 2001;13:529-38
-
(2001)
Eur J Neurosci
, vol.13
, pp. 529-538
-
-
Moss, D.W.1
Bates, T.E.2
-
96
-
-
0027354484
-
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
-
Dickson DW, Lee SC, Mattiace LA, et al. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 1993;71:75-83
-
(1993)
Glia
, vol.71
, pp. 75-83
-
-
Dickson, D.W.1
Lee, S.C.2
Mattiace, L.A.3
-
97
-
-
0027298505
-
Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 b
-
Lee SC, Liu W, Dickson DW, et al. Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 b. J Immunol 1993;150:2659-67
-
(1993)
J Immunol
, vol.150
, pp. 2659-2667
-
-
Lee, S.C.1
Liu, W.2
Dickson, D.W.3
-
99
-
-
1242336763
-
Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis
-
Nguyen MD, D'Aigle T, Gowing G, et al. Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis. J Neurosci 2004;24:1340-9
-
(2004)
J Neurosci
, vol.24
, pp. 1340-1349
-
-
Nguyen, M.D.1
D'Aigle, T.2
Gowing, G.3
-
100
-
-
0033951505
-
Alzheimer's disease and inflammation: A review of cellular and therapeutic mechanisms
-
Halliday G, Robinson S R, Shepherd C, et al. Alzheimer's disease and inflammation: A review of cellular and therapeutic mechanisms. Clin Exper Pharmacol Physiol 2000;27:1-8
-
(2000)
Clin Exper Pharmacol Physiol
, vol.27
, pp. 1-8
-
-
Halliday, G.1
Robinson, S.R.2
Shepherd, C.3
|